The state of Ohio currently has 148 active clinical trials seeking participants for Lung Cancer research studies. These trials are conducted in various cities, including Cincinnati, Columbus, Cleveland and Dayton.
Evaluating Modifiable Biomarkers for the Prediction of Immunotherapy Response and Toxicity
Recruiting
This study evaluates gut microbiome and functional status as modifiable biomarkers in predicting immunotherapy response and toxicity in patients with stage IV non-squamous non-small cell lung cancer receiving pembrolizumab alone or in combination with pemetrexed and carboplatin on the INSIGNIA trial. The goal of this study is to estimate the extent to which future interventions that seek to rationally modify the gut microbiome and/or functional status can improve outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/20/2023
Locations: Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Conditions: Lung Non-Squamous Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
Screening for High Frequency Malignant Disease
Recruiting
The SHIELD (Screening for High Frequency Malignant Disease) study is a prospective, observational, multi-site basket design trial without randomization. The primary objective of the study is to evaluate the sensitivity and specificity of a blood-based GuardantLUNAR-2 test to detect high frequency cancer in screen-relevant populations.
Gender:
All
Ages:
Between 50 years and 80 years
Trial Updated:
04/10/2023
Locations: Gabrail Cancer Center, Canton, Ohio
Conditions: Lung Cancer
Volatile Anaesthesia and Perioperative Outcomes Related to Cancer: The VAPOR-C Trial
Recruiting
VAPOR-C is a randomised study of the impact of IV versus inhaled anaesthesia (propofol versus sevoflurane) and lidocaine versus no lidocaine on duration of disease free survival inpatients with either colorectal or non small cell lung cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/21/2023
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Colonic Cancer, Rectal Cancer, Non Small Cell Lung Cancer
Real World Treatment Experience of Patients With Breast, Lung, or GI Cancer or Multiple Myeloma Using Remote Symptom Monitoring
Recruiting
The Carevive registry collects patient characteristics, patient symptoms, and treatment experience data from patients receiving cancer treatment for breast, lung, GI or multiple myeloma. For this study, a core set of variables is collected on each patient in the Carevive platform. Patients will complete a baseline survey in person using a secured device or remotely using their own electronic device in a location of their choice. Weekly electronic Patient Reported Outcome surveys are collected fr... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/18/2022
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Breast Cancer, Lung Cancer, Gastrointestinal Cancer, Multiple Myeloma