The state of Ohio currently has 26 active clinical trials seeking participants for Migraine research studies. These trials are conducted in various cities, including Cincinnati, Columbus, Cleveland and Dayton.
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine
Recruiting
The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
02/24/2025
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio +1 locations
Conditions: Migraine
A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine
Recruiting
The reason for this 12-month, open-label study is to see if the study drug lasmiditan is safe and effective for the intermittent acute treatment of migraine in children aged 6 to 17. The study will last about 12 months and may include up to 7 visits.
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
02/24/2025
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio +1 locations
Conditions: Migraine
A Study of Galcanezumab (LY2951742) in Participants 12 to 17 Years of Age With Chronic Migraine
Recruiting
The main purpose of this study is to evaluate the efficacy and safety of galcanezumab for the preventive treatment of chronic migraine in participants 12 to 17 years of age. The primary objective is to demonstrate the superiority of galcanezumab versus placebo in the reduction of monthly migraine headache days across the 3-month double-blind treatment period.
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
02/24/2025
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio +1 locations
Conditions: Chronic Migraine
A Study of Eptinezumab in Pediatric Participants With Episodic Migraine
Recruiting
The main goal of this trial is to learn whether eptinezumab helps reduce the number of days with episodic migraine in pediatric participants.
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
02/12/2025
Locations: Childrens Hospital Medical Center of Akron, Akron, Ohio +1 locations
Conditions: Episodic Migraine
Qudexy XR for the Prevention of Migraine in Children 6 to 11 Years Old
Recruiting
A Phase 4 study to evaluate Qudexy XR for the prevention of migraine in children 6 to 11 years of age.
Gender:
ALL
Ages:
Between 6 years and 11 years
Trial Updated:
01/22/2025
Locations: Upsher-Smith Clinical Trial Site #4, Cincinnati, Ohio
Conditions: Migraine Disorders
A Trial of Eptinezumab in Participants With Migraine and Insufficient Response to Anti-CGRP Medications
Recruiting
The main goal of this trial is to learn whether eptinezumab improves migraine symptoms and quality of life of participants with migraine who did not perceive a sufficient improvement during previous treatment with therapies targeting calcitonin gene-related peptide (CGRP).
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/14/2025
Locations: Neuroscience Research Center, LLC, Canton, Ohio
Conditions: Migraine
Supraspinal Processing of Sensory Aspects of Pain
Recruiting
The goal of this basic science study is to learn about the brain mechanisms of chronic pain across different chronic pain syndromes in pediatric patients. The main questions it aims to answer are: * Are there shared and distinct brain systems engaged by different forms of pediatric chronic pain? * What are predictors of recovery from chronic pain? * What brain systems are associated with the spread of pain? For this study participants will undergo: * Functional Magnetic Resonance Imaging (fMR... Read More
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
01/03/2025
Locations: Cincinnati Children's Hospital, Cincinnati, Ohio
Conditions: Migraine in Children, Complex Regional Pain Syndromes, Musculoskeletal Pain, Functional Abdominal Pain Syndrome, Fibromyalgia
Mind Body Balance for Pediatric Migraine
Recruiting
This study uses a factorial research design to evaluate a nurse delivered mind body intervention using different doses of 3 treatment components to determine the optimized treatment for headache day reduction.
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
01/02/2025
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Headache, Headache Disorders, Headache, Migraine, Migraine, Migraine Disorders, Migraine With Aura, Migraine Without Aura, Chronic Migraine
A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine
Recruiting
To find out if eptinezumab is better than placebo (normal saline solution) in lowering the number of days with migraine in young people ages 12 to 17 with chronic migraine.
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
12/09/2024
Locations: Cincinnati Children's Hospital Medical Center - PIN, Cincinnati, Ohio
Conditions: Chronic Migraine in Children
Treatment for Migraine and Mood
Recruiting
The researchers propose a three-arm pilot study of Mindfulness-Based Cognitive Therapy (MBCT) delivered via telephone (MBCT-T), video (MBCT-V) or Enhanced Usual Care (EUC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/26/2024
Locations: The Cleveland Clinic, Cleveland, Ohio
Conditions: Migraine, Depressive Symptoms
Overlapping Pain Trajectory Study
Recruiting
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1. If spatial and temporal filtering of nociceptive information is disrupted in youth with COPCs compared with youth with localized pain conditions and healthy controls. 2. If disrupted nociceptive processing at baseline is associated with the transition from a single localized pain condition... Read More
Gender:
ALL
Ages:
Between 10 years and 19 years
Trial Updated:
08/20/2024
Locations: Cincinnati Children's Hospital, Cincinnati, Ohio
Conditions: Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain, Widespread Chronic Pain, Low Back Pain, Healthy Volunteers
Responding With Evidence and Access for Childhood Headaches
Recruiting
This comparative effectiveness study will clarify current first-line preventive treatment approaches for use by neurologists, psychologists, and primary care providers in the context of real world care, and will demonstrate the feasibility of Cognitive Behavioral Therapy (CBT) via telehealth for youth with migraine. The focus is on applying evidence-based care and enhancing access to it. CBT via telehealth while taking a clinically-prescribed, pill-based prevention therapy (amitriptyline) will b... Read More
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
05/13/2024
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio +1 locations
Conditions: Headache, Headache Disorders, Headache, Migraine, Migraine, Migraine Disorders, Migraine With Aura, Migraine Without Aura, Chronic Migraine