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Diabetes Paid Clinical Trials in Oklahoma
A listing of 12 Diabetes clinical trials in Oklahoma actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 12
The state of Oklahoma currently has 12 active clinical trials seeking participants for Diabetes research studies. These trials are conducted in various cities, including Oklahoma City, Tulsa, Norman and Edmond.
Featured Trial
Studying an Investigational Treatment in Children with Type 2 Diabetes
Recruiting
The main objectives of this study are to confirm the effectiveness and safety of an investigational treatment in adolescents and children with type 2 diabetes. The study will also assess whether the investigational treatment can improve glucose control and reduce body weight. Participants will be randomly assigned to receive either the investigational treatment or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Pediatric
Type 2 Diabetes (T2DM)
Adolescent Trials
All Conditions
Featured Trial
Heart Failure Clinical Trial
Recruiting
You or someone you love may be eligible for a heart failure clinical study. Eligible participants will receive study-related assessments, care, and treatment at no cost. You may be reimbursed for travel while participating. See if you are eligible.
Conditions:
Heart Failure
Congestive Heart Failure
Chronic Heart Failure
Heart Failure
Congestive
Featured Trial
Studying an Investigational Medication to Manage Pain
Recruiting
This Phase 3 study aims to evaluate the safety and effectiveness of an investigational medication for adults experiencing pain associated with diabetes, specifically in the lower legs. The focus will be on the investigational medication's ability to reduce daily pain levels. Throughout the 14-week study, participants will be randomly assigned to receive either the investigational medication, an already-in-market drug, or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about compensation, study requirements, and risks/benefits. Expressing interest does not commit you to participating in the study; it simply allows you to learn more about it from the research site before making an informed decision.
Conditions:
All Conditions
Diabetic peripheral neuropathy (DPN)
Diabetes
Featured Trial
Assessing an Investigational Medication on Major Adverse Cardiovascular Events Such as Heart Attack and Stroke
Recruiting
The main purpose of this study is to evaluate the cardiovascular safety of the investigational medication compared with a placebo in participants who are at an increased risk of adverse cardiovascular outcomes (ie. heart attack and stroke). Participants will be randomly assigned to receive either the investigational medication or a placebo, with safety and tolerability being monitored throughout. Should you express interest, you will be contacted directly by the research site, who will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Ischemic heart disease (IHD)
Overweight
Metabolic syndrome
Diabetes related diseases
Cardiovascular Disease
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Investigational Combined COVID-19 and Influenza Vaccine
Recruiting
This study aims to evaluate the safety, immune response, and tolerability of an investigational vaccine designed to protect against both COVID-19 and seasonal influenza in adults aged 18 to 64 years. Participants will be randomly assigned to receive the investigational vaccine or a currently available vaccine. The study involves a single vaccination followed by monitoring over several months. Should you express interest, the research site will contact you directly to provide further details and address any questions you may have about study requirements, risks/benefits, and compensation.
Conditions:
Interested in vaccine studies
All Conditions
Healthy
Preventative Trials
A Study of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus (T2DM)
Recruiting
The main purpose of this study is to assess the dose-response relationship of maridebart cafraglutide on glucose control compared with placebo.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/12/2025
Locations: Alliance for Multispecialty Research, Norman, Oklahoma
Conditions: Type 2 Diabetes Mellitus (T2DM)
DISCOVERY of Risk Factors for Type 2 Diabetes in Youth
Recruiting
The goal of the DISCOVERY study is to provide innovative critical information regarding the unique natural history of glycemic control, insulin sensitivity, and β-cell function, and their mechanistic determinates, in obese adolescents at risk for developing type 2 diabetes.
Gender:
ALL
Ages:
Between 9 years and 14 years
Trial Updated:
03/10/2025
Locations: The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Conditions: Diabetes Mellitus Type 2, Childhood-Onset
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Recruiting
TRANSFORM is a prospective, randomized, open blinded endpoint (PROBE), event-driven, pragmatic trial in patients who are at increased risk for atherosclerotic cardiovascular (CV) disease but with no known symptomatic CV disease. The trial tests the hypothesis that a Cleerly Coronary Artery Disease (CAD) Staging System-based care strategy reduces CV events compared with risk factor-based care.
Gender:
ALL
Ages:
55 years and above
Trial Updated:
03/10/2025
Locations: Medical Research International, LLC, Oklahoma City, Oklahoma +1 locations
Conditions: Diabetes Mellitus, Type 2, PreDiabetes, Metabolic Syndrome
A Study of CT-388 in Participants Who Are Overweight or Obese with Type 2 Diabetes Mellitus
Recruiting
This is a multi-center, randomized, double-blind, placebo-controlled, parallel group dose-finding study to evaluate the efficacy and safety of CT-388 at low, middle, and high doses in participants who are overweight or obese with Type 2 diabetes mellitus (T2DM).
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/28/2025
Locations: Alliance for Multispecialty Research, LLC (AMR Norman), Norman, Oklahoma
Conditions: Overweight or Obese, Type 2 Diabetes Mellitus (T2DM)
Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)
Recruiting
The purpose of this study is to investigate the efficacy and safety of retatrutide compared with semaglutide in participants with Type 2 Diabetes and inadequate glycemic control with metformin with or without sodium-glucose cotransporter-2 inhibitor (SGLT2i). The study will last about 26 months and may include up to 24 visits.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2025
Locations: Alliance for Multispecialty Research, LLC, Norman, Oklahoma +1 locations
Conditions: Diabetes Mellitus, Type 2
Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)
Recruiting
The purpose of this study is to investigate the efficacy and safety of retatrutide compared with placebo in participants with Type 2 Diabetes and renal impairment, with inadequate glycemic control on basal insulin alone or a combination of basal insulin with or without metformin and/or sodium-glucose cotransporter-2 (SGLT2) inhibitor. The study will last about 14 months and may include up to 22 visits.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: Central States Research, Tulsa, Oklahoma
Conditions: Type 2 Diabetes
SPYRAL AFFIRM Global Study of RDN with the Symplicity Spyral RDN System in Subjects with Uncontrolled HTN
Recruiting
The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in subjects treated with renal denervation.
Additionally, long-term follow-up data will also be collected from eligible subjects previously treated in the SPYRAL PIVOTAL-SPYRAL HTN-OFF MED and SPYRAL HTN-ON MED studies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/17/2025
Locations: Oklahoma Heart Hospital, Oklahoma City, Oklahoma
Conditions: Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
A Research Study to See How Much CagriSema (1.0 mg Once Weekly) Lowers Blood Sugar and Body Weight Compared to Tirzepatide (5 mg Once Weekly) in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both
Recruiting
This study will look at how much CagriSema lowers blood sugar and body weight in people with type 2 diabetes. CagriSema is a new investigational medicine. Doctors cannot yet prescribe CagriSema. CagriSema will be compared to a medicine called tirzepatide. Doctors can prescribe tirzepatide in some countries. Participants will either receive CagriSema or tirzepatide. Which treatment the participant will receive is decided by chance. For each participant, the study will last for up to 1 year and 4... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/12/2025
Locations: Triad Research Institute, Norman, Oklahoma
Conditions: Diabetes Mellitus, Type 2
Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics
Recruiting
The purpose of this research study is to determine if rifampin, an antibiotic (a medicine that treats infections), is effective in treating osteomyelitis (infection of the bone) of the foot in diabetic patients. Despite use of powerful antibiotics prescribed over a long period of time, many diabetic patients remain at a high risk for needing an amputation of part of the foot or lower leg because the osteomyelitis is not cured. Some small research studies have shown that addition of rifampin to o... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
10/03/2024
Locations: Oklahoma City VA Medical Center, Oklahoma City, OK, Oklahoma City, Oklahoma
Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes
Recruiting
This is a multicenter randomized clinical trial of 828 overweight and obese individuals with gestational diabetes designed to compare standard to intensive glycemic targets.
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
06/09/2024
Locations: University of Oklahoma, Norman, Oklahoma
Conditions: Gestational Diabetes, Pregnancy, High Risk, Overweight and Obesity
Dapagliflozin in Patients With Atrial Fibrillation (DAPA-AF)
Recruiting
The study will investigate the effect of Dapagliflozin on atrial fibrillation (AF) burden. AF burden will be defined as the percent of time spent in AF over a 2-week period, assessed by noninvasive continuous heart rhythm monitoring at baseline and at 3 months, quality of life (QOL) and validated echocardiographic indices of atrial myopathy. This knowledge will enable us to study the therapeutic potential of SGLT2i as a novel adjunct treatment for patients with DM and AF. Patients with paroxysma... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
04/29/2024
Locations: University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Conditions: Atrial Fibrillation, Diabetes Mellitus
Continuous Monitoring and Control of Hypoglycemia
Recruiting
Evaluate safety of non-adjunctive CGM use in CGM naive participants.
Gender:
All
Ages:
2 years and above
Trial Updated:
09/17/2021
Locations: University of Oklahoma Health Sciences Center Department of Pediatric Diabetes and Endocrinology, Oklahoma City, Oklahoma
Conditions: Diabetes