The state of Oklahoma currently has 5 active clinical trials seeking participants for Alzheimer's Disease research studies. These trials are conducted in various cities, including Oklahoma City, Tulsa, Norman and Edmond.
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)
Recruiting
This is a Phase 3, 38-week, randomized, double-blind, placebo-controlled, multicenter, outpatient study in subjects with psychosis associated with Alzheimer's Disease. The primary objective of the study is to evaluate relapse prevention in subjects with psychosis associated with Alzheimer's Disease treated with KarXT compared to placebo. The secondary objectives of the study are to evaluate the time from randomization to discontinuation for any reason and safety and tolerability in subjects wit... Read More
Gender:
ALL
Ages:
Between 55 years and 90 years
Trial Updated:
01/06/2025
Locations: Local Institution - 1028, Oklahoma City, Oklahoma +1 locations
Conditions: Psychosis Associated With Alzheimer's Disease
Clinical Trial on Agitation in Alzheimer's Dementia
Recruiting
The purpose of this study is to assess the efficacy of the oral medication IGC-AD1, a THC-based (Delta-9-Tetrahydrocannabinol) formulation administered twice a day on Agitation in patients with mild to severe dementia from Alzheimer's.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
01/06/2025
Locations: Lynn Health Science Institute (LHSI), Oklahoma City, Oklahoma
Conditions: Alzheimer Disease, Agitation,Psychomotor, Care Giving Burden, NPS, Aggression
Efficacy and Safety of GSK4527226 [AL101] in Participants With Early Alzheimer's Disease
Recruiting
The aim of this study is to assess the efficacy and safety of GSK4527226 in participants with early Alzheimer's Disease (AD) (including mild cognitive impairment \[MCI\] and mild dementia due to AD) of 2 dose levels of GSK4527226 compared to placebo.
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
12/04/2024
Locations: GSK Investigational Site, Oklahoma City, Oklahoma
Conditions: Alzheimer's Disease
A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease
Recruiting
This is a multicenter randomized, double-blind, placebo-controlled Phase 2 study designed to evaluate the efficacy, safety, and tolerability of two doses of CT1812 compared to placebo in participants diagnosed with early Alzheimer's disease.
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
11/21/2024
Locations: Central States Research, LLC, Tulsa, Oklahoma
Conditions: Early Alzheimer's Disease
Phase 2b Efficacy and Safety Study of Fixed Dose Drugs Combination Type of Polypill
Recruiting
The goal of this clinical trial is to assess the clinical response to a drug combination type of polypill in patients with AD after 180 days of treatment. The anticipated study population are males and females aged 50-85 years with mild to severe Alzheimer's Disease. The duration of individual patient participation will be approximately 224 Days: up to 14 days for Screening, 180 days for study drug administration, and a final follow-up visit at 210 days. The planned study duration is 12-18 month... Read More
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
11/20/2024
Locations: Tekton Research (Noah Clinical Site 002), Yukon, Oklahoma
Conditions: Alzheimer Disease