There are currently 997 clinical trials in Portland, Oregon looking for participants to engage in research studies. Trials are conducted at various facilities, including Oregon Health & Science University, Oregon Health and Science University /ID# 216891, Providence Portland Medical Center and Providence Saint Vincent Medical Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration
NCT04071457
Recruiting
Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first randomization). Patients are randomized between Lenalidomide for 2 years and Lenalidomide + Daratumumab/rHuPH20. After 2 years of Maintenance, MRD is assessed to guide further therapy. MRD-positive patients will continue with the assigned treatment. MRD-negative patients will be further randomized (Reg Ste... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/21/2024
Locations: Legacy Good Samaritan Hospital and Medical Center, Portland, Oregon +5 locations
Conditions: Multiple Myeloma
Register for Updates
Pediatric Precision Laboratory Advanced Neuroblastoma Therapy
NCT02559778
Recruiting
A prospective open label, multicenter study to evaluate the feasibility and acute toxicity of using molecularly guided therapy in combination with standard therapy followed by a Randomized Controlled Trial of standard immunotherapy with or without DFMO followed by DFMO maintenance for Subjects with Newly Diagnosed High-Risk Neuroblastoma.
Gender:
ALL
Ages:
22 years and below
Trial Updated:
08/21/2024
Locations: Randall Children's Hospital, Portland, Oregon
Conditions: Neuroblastoma
Register for Updates
Intravenous Versus Oral Iron for Treating Iron-Deficiency Anemia in Pregnancy
NCT05462704
Recruiting
Double blind, placebo controlled, multicenter randomized trial in pregnant women in the U.S. (N=746) to test the central hypothesis that IV iron in pregnant women with moderate-to-severe IDA (Hb\<10 g/dL and ferritin\<30 ng/mL) at 13 - 30 weeks will be effective, safe and cost-effective in reducing severe maternal morbidity-as measured by peripartum blood transfusion-and will also improve offspring neurodevelopment.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
08/20/2024
Locations: Oregon Health and Sciences Uiversity Medical Center, Portland, Oregon
Conditions: Iron Deficiency Anemia, Pregnancy
Register for Updates
Catalyst CSR Shoulder System for Semi or Total Shoulder Arthroplasty
NCT04968405
Recruiting
Evaluation of the performance and safety of the Catalyst CSR Shoulder System with clinical and radiographic results at multiple time points through 24 months postoperatively This study will be a prospective multi-center study conducted in the United States.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: Kaiser Permanente Northwest Center for Health Research, Portland, Oregon
Conditions: Osteoarthritis Shoulder, Avascular Necrosis of the Head of Humerus, Rheumatoid Arthritis Shoulder
Register for Updates
IUD Self-Removal Study
NCT05339555
Recruiting
This is a pilot study designed to test the effectiveness of several techniques for intrauterine device (IUD) self-removal and to understand patient preferences regarding IUD self-removal and indicators of success as well as understanding the impacts of IUD self-removal on other clinical care.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
08/19/2024
Locations: Oregon Health & Science Univeristy, Portland, Oregon
Conditions: IUD
Register for Updates
Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis
NCT04380740
Recruiting
This is a multicenter randomized, double blind, Phase 2 trial for patients receiving transplants from 7 of 8 HLA matched donors, in which an extended dosing regimen of abatacept, and a short-term dosing regimen + placebo, when added to standard calcineurin inhibitor + methotrexate-based prophylaxis, will be compared for their ability to improve outcomes in patients with a minimum follow-up of one year post-transplant. All patients will receive 4 doses of abatacept (Days -1, +5, +14, +28). Prior... Read More
Gender:
ALL
Ages:
2 years and above
Trial Updated:
08/19/2024
Locations: Oregon Health and Sciences University, Portland, Oregon
Conditions: Graft Vs Host Disease
Register for Updates
High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers
NCT05011383
Recruiting
This study will determine whether the presence of DNA repair deficiency in the form of alterations in the genes ATM, CDK12 or CHEK2 predicts for a high likelihood of responding to the use of intermittent high dose testosterone. This therapy may result in responses in tumors which are genetically unstable because of DNA repair deficiency and this is a prospective study to test that hypothesis
Gender:
MALE
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: VA Portland Health Care System, Portland, OR, Portland, Oregon
Conditions: Metastatic Prostate Cancer
Register for Updates
The Over The Counter Pill National Study
NCT05988983
Recruiting
This is a prospective cohort study of individuals purchasing the oral contraceptive pill over the counter (OTC) in pharmacies in 32 US states. The comparison group is people receiving a prescription (Rx) for oral contraception. Both groups will be followed for one year to examine contraceptive continuation rates. This study will also identify who is using the pill OTC and why and evaluate differences in pregnancy intention and measures of contraceptive agency between the two groups.
Gender:
FEMALE
Ages:
Between 12 years and 51 years
Trial Updated:
08/16/2024
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Contraception, Contraception Behavior, Contraceptive Usage, Health Care Utilization
Register for Updates
Disparities in Emergency Contraceptive Metabolism Dictate Efficacy
NCT05674513
Recruiting
The purpose of this study is to learn more about why some people are at greater risk for oral emergency contraceptive failure while others are not. The investigators want to learn if genetic differences impact the risk of emergency contraception failure.
Gender:
FEMALE
Ages:
Between 18 years and 40 years
Trial Updated:
08/16/2024
Locations: OHSU, Portland, Oregon
Conditions: Contraceptive Usage
Register for Updates
Center M: Digital Health Innovation Pilot
NCT06000449
Recruiting
Center M is a digital health solution to Perinatal Depression (PD) which provides an alternative to Mindfulness Based Cognitive Therapy - Perinatal Depression (MBCT-PD). Center M shifts treatment to a telehealth model, reduces the number of sessions, and transitions home practice materials to a digital format. This study will include a clinical trial in which participants will be randomized to the Center M treatment with smartphone app delivery of homework compared to treatment as usual (TAU).
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
08/16/2024
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Perinatal Depression
Register for Updates
PAI-1, tPA, TFPI and HEECs in Uterine Hemostasis
NCT05862805
Recruiting
The purpose of the study is to learn more about the role of blood clotting factor proteins and cells in menstrual (period) bleeding. The investigators are hoping to identify differences in these proteins and cells in the menstrual blood of individuals with heavy periods compared to menstruating individuals who do not have heavy periods.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
08/16/2024
Locations: OHSU, Portland, Oregon
Conditions: Menstrual Bleeding, Heavy
Register for Updates
Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial
NCT05991453
Recruiting
The investigators will conduct a 12,500-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (ii) whether TIVA confers no more than a small (0.2 %) increased risk of intraoperative awareness than INVA in patients undergoing both outpatient and inpatient surgeries
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/15/2024
Locations: Oregon Health and Sciences University, Portland, Oregon
Conditions: Surgery-Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia, Surgery, Quality of Life, Pain, Postoperative, Anesthesia Morbidity
Register for Updates