The city of Portland, Oregon, currently has 12 active clinical trials seeking participants for Pain research studies.
Cemented Vs Cementless Persona Keel RCT
Recruiting
The main objective of this study is to evaluate the safety, performance, and clinical benefits of the Persona Keel cementless and cemented knee.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/21/2025
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Knee Pain Chronic, Rheumatoid Arthritis, Osteoarthritis, Traumatic Arthritis, Polyarthritis, Avascular Necrosis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee
Tele-Collaborative Outreach to Rural Patients with Chronic Pain
Recruiting
This is a randomized controlled trial comparing the effectiveness of a remotely delivered collaborative care intervention for chronic pain versus a minimally enhanced control group. The specific aims of the study are: (1) compare the effectiveness of tele-collaborative pain care vs. minimally enhanced usual care to improve pain interference over 12 months of follow-up, and (2) oversample women and rural veterans of minoritized race/ethnicity to test heterogeneity of treatment effects across birt... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/18/2025
Locations: VA Portland Health Care System, Portland, Oregon
Conditions: Chronic Pain
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Recruiting
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.
Gender:
ALL
Ages:
Between 0 years and 20 years
Trial Updated:
03/11/2025
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Hemophilia, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
Patient Retrospective Outcomes (PRO)
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/05/2025
Locations: Summit Spine, Portland, Oregon
Conditions: Chronic Pain
Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response
Recruiting
VETERANS ONLY. Chronic low back pain (cLBP) is common. Most Americans will have at least one episode of low back pain in their lifetimes. Approximately 50% of all US Veterans have chronic pain, and CLBP is the most common type of pain in this population. This study will use a sequential randomized, pragmatic, 2-step comparative effectiveness study design. The main goal is to identify the best approach for treating cLBP using commonly recommended non-surgical and non-pharmacological options. The... Read More
Gender:
ALL
Ages:
All
Trial Updated:
03/04/2025
Locations: VA Portland Health Care System, Portland, OR, Portland, Oregon
Conditions: Chronic Low Back Pain
Anesthetics and Analgesics in Children
Recruiting
The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.
Gender:
ALL
Ages:
Between 0 years and 17 years
Trial Updated:
01/21/2025
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Anesthesia, Pain
Vestibulectomy Surgical Techniques Comparison Study
Recruiting
Vestibulectomy Surgical Techniques Comparison Study
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
09/06/2024
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Vulvar Pain, Vulvodynia
Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial
Recruiting
The investigators will conduct a 12,500-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (ii) whether TIVA confers no more than a small (0.2 %) increased risk of intraoperative awareness than INVA in patients undergoing both outpatient and inpatient surgeries
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/15/2024
Locations: Oregon Health and Sciences University, Portland, Oregon
Conditions: Surgery-Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia, Surgery, Quality of Life, Pain, Postoperative, Anesthesia Morbidity
Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment
Recruiting
This study seeks to improve the treatment of chronic pain in people who are taking buprenorphine (also known as Suboxone, Subutex, Zubsolv). The research study is testing two different interventions along with usual clinical care: 1. Pain Self-Management (PSM): an educational program in which individuals with chronic pain work with a trained pain coach and a pain peer to explore strategies to effectively manage the daily problems that arise from chronic pain. 2. Patient-Oriented Dosing (POD):... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/01/2024
Locations: Central City Concern (CCC), Portland, Oregon +3 locations
Conditions: Opioid Use Disorder, Chronic Pain
COMmunity of Practice And Safety Support for Navigating Pain (COMPASS-NP)
Recruiting
Home care workers (HCWs) are at-risk for chronic pain and associated problems, including emotional distress, opioid use and misuse, and work-related disability. To address these issues, the proposed study will adapt an established peer-led and supportive group program to address the needs of HCWs with chronic pain. The new program, named COMPASS for Navigating Pain (COMPASS-NP), will integrate work-based injury protections with pain education and cognitive-behavioral therapy strategies for pain... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/16/2024
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Pain Management, Ergonomics, Wounds and Injuries
Brown Adipose Tissue Activation by Spinal Cord Stimulation
Recruiting
The objective of this study is to investigate and utilize spinal cord stimulation (SCS) as an effective approach to eliciting weight loss and potentially alleviating Type 2 diabetes mellitus (DM), as evidenced by increasing metabolism of adipose tissue.
Gender:
All
Ages:
Between 21 years and 70 years
Trial Updated:
04/01/2024
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Pain, Back, Obesity, Morbid, Type 2 Diabetes
Pragmatic Trial of WHT vs. PC-GE to Promote Non-Pharmacological Strategies to Treat Chronic Pain in Veterans
Recruiting
The overarching goal of this Pain Management Collaboratory Demonstration project is to test a new Whole Health paradigm for chronic pain care, emphasizing non-pharmacological pain self-management that is hypothesized to reduce pain symptoms and improve overall functioning and quality of life in Veterans. In UH3 Aim 1, the investigators will conduct a 12-month pragmatic effectiveness trial at 5 VA sites across the country to test whether veterans with moderate to severe chronic pain randomized to... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/21/2020
Locations: VAPHCS, Portland, Oregon
Conditions: Chronic Pain