The state of Pennsylvania currently has 6 active clinical trials seeking participants for Primary Biliary Cholangitis research studies. These trials are conducted in various cities, including Philadelphia, Pittsburgh, Hershey and Allentown.
IDEAL: Intended to Determine the Effects of Seladelpar on Normalization of Alkaline Phosphatase Levels in Subjects With Primary Biliary Cholangitis (PBC) and an Incomplete Response or Intolerance to Ursodeoxycholic Acid (UDCA)
Recruiting
To Determine the Effects of Seladelpar on Normalization of Alkaline Phosphatase Levels in Subjects with Primary Biliary Cholangitis (PBC) and an Incomplete Response or Intolerance to Ursodeoxycholic Acid (UDCA)
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/18/2025
Locations: Perelman Center for Advanced Medicine, Philadelphia, Pennsylvania +2 locations
Conditions: Primary Biliary Cholangitis
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis
Recruiting
The purpose of this clinical research study is to learn more about the use of the study medicine, volixibat, for the treatment of pruritus (itching) associated with Primary Biliary Cholangitis (PBC), and to assess the possible impact on the disease progression of PBC.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: Einstein Healthcare Network - Einstein Medical Center, Philadelphia, Pennsylvania
Conditions: Primary Biliary Cholangitis, PBC
A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary Cholangitis
Recruiting
The participants of this study will have confirmed Primary Biliary Cholangitis (PBC) and cirrhosis (scarring of the liver). PBC is a slowly progressive disease, characterised by damage to the bile ducts in the liver, leading to a build-up of bile acids which causes further damage. The liver damage in PBC may lead to cirrhosis. PBC may also be associated with multiple symptoms. Many patients with PBC may require liver transplant or may die if the disease progresses and a liver transplant is not... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2025
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Primary Biliary Cholangitis (PBC)
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
Recruiting
To Evaluate the Effect of Seladelpar on Clinical Outcomes in Patients with Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/16/2025
Locations: Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania +3 locations
Conditions: Primary Biliary Cholangitis
Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.
Recruiting
Study to investigate the efficacy and safety of two doses of K-808 (pemafribate) in subjects with PBC.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: Einstein Medical Center, Philadelphia, Pennsylvania
Conditions: Primary Biliary Cholangitis
Open-Label Extension Study of Saroglitazar Magnesium in Participants with Primary Biliary Cholangitis
Recruiting
Open-Label Extension Study of Saroglitazar Magnesium in Participants With Primary Biliary Cholangitis
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/29/2024
Locations: Zydus US015, Philadelphia, Pennsylvania
Conditions: Primary Biliary Cholangitis