The state of Pennsylvania currently has 20 active clinical trials seeking participants for Osteoarthritis research studies. These trials are conducted in various cities, including Philadelphia, Pittsburgh, Hershey and Allentown.
Study of PIPE-791 for Subjects with Chronic Osteoarthritis Pain or Chronic Low Back Pain
NCT06810245
Recruiting
The primary goal of this clinical trial is to learn if PIPE-791 is safe and well-tolerated in adults with chronic osteoarthritis pain (COAP) or chronic low back pain (CLBP). The study will also explore whether PIPE-791 lowers pain in people with COAP or CLBP. Subjects will: * Complete a washout period to stop their current pain medications. * Take a daily dose of PIPE-791 or placebo for 4 weeks, then reverse treatment assignment for another 4 weeks. * Record pain levels and track dosing in a d... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
02/26/2025
Locations: Altoona Center of Clinical Research, Duncansville, Pennsylvania
Conditions: Chronic Osteoarthritis Pain, Chronic Low Back Pain
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Persona Revision Knee System Outcomes
NCT04821154
Recruiting
The study will evaluate the performance, clinical benefits and safety of the Persona Revision Knee System in patients who have received primary or revision total knee arthroplasty (TKA) treatment. This will be done using a multicenter, single-arm, consecutive series, retrospective cohort study with prospective follow-up.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2025
Locations: Penn Medicine/ Lancaster General Health, Lancaster, Pennsylvania
Conditions: Arthroplasty Complications, Infection, Knee Disease, Knee Osteoarthritis
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Evaluation of Structural and Functional Integrity of the Rotator Cuff After Total Shoulder Arthroplasty
NCT03921944
Recruiting
The purpose of this study is to examine the rotator cuff muscles in your shoulder at one and two year post total shoulder replacement surgery.
Gender:
ALL
Ages:
45 years and above
Trial Updated:
01/07/2025
Locations: Penn State Hershey Medical Center, Hershey, Pennsylvania
Conditions: Osteoarthritis of Shoulder
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Oral Nutritional Optimization in Total Joint Arthroplasty
NCT04210284
Recruiting
The purpose of this study is to determine the effect on hematological markers of nutritional intervention on nutritionally deficient patients following total joint replacement surgery.
Gender:
ALL
Ages:
55 years and above
Trial Updated:
10/28/2024
Locations: Rothman Orthopedic Institute, Philadelphia, Pennsylvania
Conditions: Osteoarthritis
Register for Updates
AETOS Shoulder System
NCT06319911
Recruiting
The goal of this study is to confirm the safety and performance of the AETOS Shoulder System for USA adoption. This is a prospective, open, adaptive, non-comparative, multi-centre investigation enrolling a maximum of 220 subjects in 2 cohorts (anatomic and reverse) at up to 15 sites. No intra-study comparator group will be included, and there will be no randomization
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: Rothman Institute, Philadelphia, Pennsylvania
Conditions: Shoulder Osteoarthritis, Shoulder Arthritis
Register for Updates
Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Shoulder
NCT02844738
Recruiting
This is a prospective open-label clinical study of 50 patients to determine safety and treatment potential of autologous cell therapy for pain and inflammation associated with Osteoarthritis of the shoulder. Follow-up will consist of a larger sample including 4,000 patients.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
08/04/2023
Locations: VivaTech International, Inc., Grove City, Pennsylvania
Conditions: Osteoarthritis
Register for Updates
Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Knee
NCT02844751
Recruiting
This is a prospective open-label clinical study of 50 patients to determine safety and treatment potential of autologous cell therapy for pain and inflammation associated with Osteoarthritis of the knee. Follow-up will consist of a larger sample including 4,000 patients.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
08/04/2023
Locations: VivaTech International, Inc., Grove City, Pennsylvania
Conditions: Osteoarthritis
Register for Updates
Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Hip
NCT02844764
Recruiting
This is a prospective open-label clinical study of 50 patients to determine safety and treatment potential of autologous cell therapy for pain and inflammation associated with Osteoarthritis of the hip. Follow-up will consist of a larger sample including 4,000 patients.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
08/04/2023
Locations: VivaTech International, Inc., Grove City, Pennsylvania
Conditions: Osteoarthritis
Register for Updates