The city of Charleston, South Carolina, currently has 5 active clinical trials seeking participants for Healthy research studies.
tFUS Induced Transient Scotoma for Individual Dosing
Recruiting
The purposes of this research study is to: Develop a technique of transcranial Focused Ultrasound Stimulation (tFUS) where meaningful effects on the brain can be easily measured. Use this technique to measure threshold for effective tFUS in individuals. Determine whether disruption of conscious visual detection, versus non-conscious visually-guided behavior have different thresholds for disruption with tFUS.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
06/04/2024
Locations: Medical University of South Carolina Brain Stimulation Division, Charleston, South Carolina
Conditions: Healthy
RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS
Recruiting
In this research study, the investigators are using examining how brain activity (electrical and blood flow) changes during tests of emotional processing and attention and memory in the magnetic resonance imaging (MRI) scanner. Investigators are also using non-invasive brain stimulation to probe different parts of the brain and measuring brain activity (electrical and blood flow). This study includes healthy participants and researchers hope this will help us develop improved brain-based treatme... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/25/2024
Locations: Medical Univeristy of South Carolina, Charleston, South Carolina
Conditions: Healthy
Safety Assessment of Central Medial Thalamus Stimulation Using Transcranial Focused Ultrasound
Recruiting
The purposes of this research study are to investigate closed-loop and personalized focused ultrasound as a technique to study how the brain works and to evaluate the safety and effectiveness of the Attune ATTN201 device. This study will objectively assess brain parenchyma morphology, and neuropsychiatric and neuropsychological function, following Transcranial Focused Ultrasound (tFUS) exposure. Electroencephalographic recordings during parametric sweeps will be obtained for observation of chang... Read More
Gender:
All
Ages:
Between 22 years and 55 years
Trial Updated:
04/16/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Healthy
Transcranial Focused Ultrasound (tFUS) Modulation of Reward Network
Recruiting
Aim: Evaluate whether sonicating the Nucleus Accumbens (NAc) with transcranial focused ultrasound modifies functional connectivity between the NAc and the prefrontal cortex (PFC). In this single visit, open-label pilot trial, we plan to evaluate whether transcranial focused ultrasound (tFUS), delivered to the nucleus accumbens (NAc) within the magnetic resonance imaging (MRI) scanner will impact resting state functional connectivity between the NAc and functionally connected brain regions like... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
08/09/2023
Locations: Medical University of South Carolina Institute of Psychiatry, Charleston, South Carolina
Conditions: Healthy
Spectral Characteristics of Memory Transformation
Recruiting
Sometimes, it is necessary to re-learn a previously learned movement behavior, for example, a bad posture during the golf drive or while playing the piano. Unlearning or relearning an intensively trained behavior is particularly important if the behavior is hampering recovery, for example, in chronic pain or after a stroke. With this pilot study, the brain mechanisms that control the change of pre-existing stable memories of a motor skill will be tested with electroencephalography (EEG). Non-inv... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/07/2023
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Healthy