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Pain Clinical Trials in Knoxville, TN
A listing of 4 Pain clinical trials in Knoxville, TN actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 4 of 4
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The city of Knoxville, Tennessee, currently has 4 active clinical trials seeking participants for Pain research studies.
Featured Trial
Healthy Participants Needed (Colonoscopy + Cancer Screening)
Recruiting
Earn $325 - $475 in electronic payment card compensation for your time and effort by participating in a clinical study to develop a blood test that may one day help screen for colon cancer. Take a quick quiz to see if you qualify.
Conditions:
Healthy
Healthy Volunteers
Healthy Subjects
Healthy Volunteer
Healthy Participants
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Conditions:
Healthy
Healthy Volunteer Study
Featured Offer
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Semaglutide and Tirzepatide are advanced GLP-1 medications designed to support weight management and metabolic health. They work by targeting GLP-1 receptors in the body, helping regulate appetite, improve blood sugar control, and support sustainable weight loss (up to 22% of body weight).
Get $50 off your first order using promo code: policy-lab-50
Semaglutide and Tirzepatide are advanced GLP-1 medications designed to support weight management and metabolic health. They work by targeting GLP-1 receptors in the body, helping regulate appetite, improve blood sugar control, and support sustainable weight loss (up to 22% of body weight).
Get $50 off your first order using promo code: policy-lab-50
Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
Featured Trial
Chronic Cough Study
Recruiting
Are you tired of living with chronic cough? The ASPIRE Study is now looking to enroll people from all backgrounds to help research potential new treatment options for chronic cough. You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you.
Conditions:
Chronic Cough
Refractory or Unexplained Chronic Cough
Cough
Asthma
Allergic Asthma
Featured Procedure
Lower Limb Post-Amputation Pain?
Chronic Amputation Pain of the Lower Limb can make everyday movements feel like uphill battles.
In a clinical study, Altius patients reported real progress:
- 44% increase in walking ability
- 45% improvement in overall quality of life
Take the survey to learn more about Altius as a pain relief option for chronic amputation pain of the lower limb.
Consult with a doctor. Risks may include surgical, device, and stimulation-related complications. Results may vary.
In a clinical study, Altius patients reported real progress:
- 44% increase in walking ability
- 45% improvement in overall quality of life
Take the survey to learn more about Altius as a pain relief option for chronic amputation pain of the lower limb.
Consult with a doctor. Risks may include surgical, device, and stimulation-related complications. Results may vary.
Conditions:
Amputation
Lower Limb Amputation
Lower Limb Amputation Above Knee (Injury)
Lower Limb Amputation Below Knee (Injury)
Phantom Limb Pain
Featured Trial
Buy Retatrutide Online Through Celia
Recruiting
Retatrutide (formerly M25) is an investigational peptide being studied for its potential in supporting weight management and metabolic health. It acts on GLP-1, GIP, and glucagon receptors to influence appetite, energy regulation, and fat metabolism.
Conditions:
Healthy
A Single-arm Study Evaluating the Effectiveness and Safety of Suzetrigine (SUZ) for Acute Pain After Selected Surgeries
Recruiting
The purpose of this study is to evaluate the effectiveness, safety, and tolerability of SUZ for acute pain after laparoscopic procedures of the intraperitoneal or retroperitoneal cavities or arthroscopic orthopedic procedures.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2025
Locations: University of Tennessee Medical Center - Anethesiology, Knoxville, Tennessee
Conditions: Acute Pain
Effects of LY3848575 Versus Placebo in Participants With Painful Distal Sensory Polyneuropathy
Recruiting
The purpose of this study is to evaluate how safe and how well a treatment works compared to placebo for people with nerve pain that begins in their feet and moves up the leg to just below the knee.
Participation may last up to 30 weeks including screening.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/22/2025
Locations: New Phase Research and Development, Knoxville, Tennessee
Conditions: Neuropathic Pain, Distal Sensory Polyneuropathy
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain
Recruiting
The main purpose of this study is to evaluate the efficacy and safety of retatrutide in relieving chronic low back pain in participants who have obesity or overweight. Participation in the study will last about 80 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2025
Locations: New Phase Research and Development, Knoxville, Tennessee
Conditions: Obesity, Overweight, Chronic Low Back Pain (CLBP)
No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair
Recruiting
The investigators hypothesize that not prescribing opioids after uncomplicated, outpatient IHR will be non-inferior to prescribing opioids (5 tablets of Oxycodone, 5mg; or surgeon preference for intolerance) with respect to requests for opioid refills. Additionally, the investigators believe there will be no significant difference in postoperative readmission for pain quality of life at 30 days in either group.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/07/2025
Locations: University of Tennessee Medical Center, Knoxville, Tennessee
Conditions: Postoperative Pain, Inguinal Hernia
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