The city of Memphis, Tennessee, currently has 5 active clinical trials seeking participants for Epilepsy research studies.
Dose-Escalation Study of Cenobamate (YKP3089) in Pediatric Subjects With Partial-Onset Seizures
Recruiting
The primary objective of this study is to assess the pharmacokinetics of cenobamate (YKP3089) in pediatric subjects with partial-onset (focal) seizures following single and multiple-dosing.
Gender:
All
Ages:
Between 2 years and 18 years
Trial Updated:
05/28/2024
Locations: Le Bonheur Children's Hospital, Memphis, Tennessee
Conditions: Partial Epilepsy
Randomized, Double-Blind Study to Evaluate Efficacy and Safety of Cenobamate Adjunctive Therapy in PGTC Seizures
Recruiting
This trial is intended to study the safety and effectiveness of an new anti-epileptic drug (AED) on Primary Generalized Tonic-Clonic (PGTC) Seizures. Eligible Subjects, adults and adolescents, will continue to take their usual AEDs and receive either cenobamate or placebo. Subjects will have a 50% chance or receiving cenobamate or placebo (sugar pill). Subjects will initially receive 12.5 mg of cenobamate or placebo (study drug) and increase the dose every two weeks until they reach a target dos... Read More
Gender:
All
Ages:
12 years and above
Trial Updated:
04/03/2024
Locations: LeBonheur Children's Medical Center, Memphis, Tennessee
Conditions: Primary Generalized Epilepsy
RNS System RESPONSE Study
Recruiting
To demonstrate that the RNS System is safe and effective as an adjunctive therapy in individuals age 12 through 17 years with medically refractory partial onset epilepsy.
Gender:
All
Ages:
Between 12 years and 17 years
Trial Updated:
02/06/2024
Locations: Le Bonheur Children's Foundation Research Institute, Memphis, Tennessee
Conditions: Epilepsy, Partial Seizure, Neurostimulator; Complications, Drug Resistant Epilepsy, Focal Epilepsy
Safety and Efficacy Study of Cenobamate in Pediatric Subjects 2-17 Years of Age With Partial-onset (Focal) Seizures
Recruiting
Primary objective: To evaluate the safety and tolerability of cenobamate in pediatric subjects 2-17 years of age with partial-onset (focal) seizures
Gender:
All
Ages:
Between 2 years and 18 years
Trial Updated:
01/30/2024
Locations: Le Bonheur Children's Hospital, Memphis, Tennessee
Conditions: Partial Epilepsy
A Study of Detection of Paroxysmal Events Utilizing Computer Vision and Machine Learning - Nelli
Recruiting
Nelli is a video-based non-EEG physiological seizure monitoring system. This study is a blinded comparison of Nelli's identified events to gold-standard video EEG review in at-rest pediatric subjects with suspected motor seizures.
Gender:
All
Ages:
Between 6 years and 21 years
Trial Updated:
11/08/2023
Locations: The University of Tennessee Health Science Center, Memphis, Tennessee
Conditions: Epilepsy