The city of Austin, Texas, currently has 1 active clinical trials seeking participants for Amyotrophic Lateral Sclerosis research studies.
A Study of BIIB067 (Tofersen) Initiated in Clinically Presymptomatic Adults With a Confirmed Superoxide Dismutase 1 Mutation
The primary objective of this study is to evaluate the efficacy of tofersen in presymptomatic adult carriers of a superoxide dismutase 1 (SOD1) mutation with elevated neurofilament (NF). The secondary objectives of this study are to evaluate the safety and tolerability tofersen and to evaluate the effect of tofersen on pharmacodynamics (PD)/treatment response biomarkers when initiated prior to versus at the time of emergence of clinically manifest amyotrophic lateral sclerosis (ALS).
18 years and above
Trial Updated:
Locations: Austin Neuromuscular Center, Austin, Texas
Conditions: Amyotrophic Lateral Sclerosis Associated With a SOD1 Gene Mutation