There are currently 12 active clinical trials seeking participants for Acute Coronary Syndrome research studies. The states with the highest number of trials for Acute Coronary Syndrome participants are Florida, California, Texas and Pennsylvania.
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS
NCT05918861
Recruiting
This is a placebo-controlled, randomized, double-blind, parallel group, phase 3 multicenter study in subjects recently hospitalized for ACS and with the appropriate genetic profile. Subjects will provide informed consent before any study-specific procedures are performed. A separate informed consent will be allowed for an initial pre-screening genetic testing. Subjects meeting the AA genotype will then consent to the full study and confirmatory genetic testing as required. Subject enrollment may... Read More
Gender:
All
Ages:
45 years and above
Trial Updated:
06/21/2024
Locations: Research Site, Alexander City, Alabama +153 locations
Conditions: Acute Coronary Syndrome
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A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome
NCT05754957
Recruiting
The purpose of this study is to evaluate that milvexian is superior to placebo, in addition to standard-of-care, in reducing the risk of major adverse cardiovascular event (MACE) (the composite of cardiovascular [CV] death, myocardial infarction [MI], and ischemic stroke).
Gender:
All
Ages:
18 years and above
Trial Updated:
06/18/2024
Locations: Advanced Cardiovascular, LLC, Alexander City, Alabama +821 locations
Conditions: Acute Coronary Syndrome
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Polypill in Acute Coronary Syndrome
NCT05514938
Recruiting
Acute coronary syndromes (ACS) represent a major contributor to mortality, morbidity, and healthcare costs. Effective therapies are widely available; however, adherence is low. This contributes to worse patient outcomes and increased risk of morbidity and mortality. The once-daily polypill leverages a population-based strategy that has previously demonstrated efficacy in improving adherence and access to therapy in low-resource settings, making it an innovative approach for improving post-ACS ca... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/28/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Acute Coronary Syndrome, Lipid Disorder, Coronary Artery Disease
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Healthy Heart Habits-2
NCT06440278
Recruiting
Sixty adults who have experienced acute coronary syndrome within the past 2-12 months from three states (Rhode Island, North Carolina, Minnesota) will be randomized to either (1) a coaching program for depressed mood and health behavior change (Behavioral Activation for Health and Depression; BA-HD), or (2) Enhanced Usual Care. This study will evaluate the feasibility and acceptability of study procedures and BA-HD, and establish protocol and measurement harmonization across three sites in prepa... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/28/2024
Locations: Hennepin Healthcare Research Institute, Minneapolis, Minnesota +2 locations
Conditions: Acute Coronary Syndrome
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Positive Emotions Following Acute Cardiac Events
NCT05412862
Recruiting
The focus of this study is to test the efficacy of a 12-week, remotely delivered, positive-psychology-motivational interviewing (PP-MI) intervention, with additional twice weekly text messages for a total of 24 weeks (with interactive, algorithm-driven, goal-focused text messages in the final 12 weeks), compared to post-acute coronary syndrome (ACS) treatment as usual, in a randomized trial of 280 post-ACS patients with low baseline physical activity.
Gender:
All
Ages:
Between 18 years and 95 years
Trial Updated:
04/16/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Acute Coronary Syndrome, Physical Inactivity
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Multidisciplinary Approach to Reduce Cardiovascular Health Disparities
NCT06168968
Recruiting
The goal of this observational study is to investigate the potential differences in thrombogenicity between black and white patients admitted with atherothrombotic events including acute coronary syndrome, multi-vessel coronary disease, and ischemic stroke. Participants will engage in laboratory testing and health outcome assessments.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/05/2023
Locations: Sinai Hospital of Baltimore, Baltimore, Maryland
Conditions: Acute Coronary Syndrome, Multi Vessel Coronary Artery Disease, Ischemic Stroke
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Identification of Predictors for Coronary Plaque Erosion in Patients With Acute Coronary Syndrome
NCT03479723
Recruiting
The purpose of this study is to perform pooled analysis with data collected from 5 previously published studies and 8 unpublished datasets collected from international sites. The main goal of this study is to identify the predictors of plaque erosion.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/19/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Acute Coronary Syndrome
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Acute Coronary Syndrome KCMC
NCT04563546
Recruiting
The purpose of this study is to develop a quality improvement intervention to address barriers to evidence-based acute coronary syndrome (ACS) care in northern Tanzania. Patients who presented to Kilimanjaro Christian Medical Center (KCMC) will be asked to complete a survey about barriers and facilitators of health care. In addition the survey will be administered to all providers, policymakers, and administrators participating in in-depth interviews. Data from this survey will be used to develo... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/06/2023
Locations: Duke University Hospital, Durham, North Carolina
Conditions: Acute Coronary Syndrome
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Improving Cardiac Rehabilitation Outcomes Through Mobile Case Management (iCARE)
NCT04938661
Recruiting
The purpose of this research is to find out if doing cardiac rehab at home, or a mix of cardiac rehab at home and in the clinic, is as effective as coming in to the clinic for cardiac rehab.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
08/28/2023
Locations: University of Minnesota, Minneapolis, Minnesota +1 locations
Conditions: Acute Myocardial Infarction, Acute Coronary Syndrome, Stable Angina Pectoris, Percutaneous Coronary Intervention, Heart Failure
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AngelMed Guardian® System PMA Post Approval Study
NCT05412927
Recruiting
500 Patients (minimum) will be enrolled following commercial implant. Will be treated by their physicians using the standard of care. Standard of care for the Guardian includes an in-office initial programming visit 7-14 days following implant and every 6 months.
Gender:
All
Ages:
21 years and above
Trial Updated:
08/18/2023
Locations: CardioVascular Associates of Mesa, Mesa, Arizona +13 locations
Conditions: Acute Coronary Syndrome
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Left Ventricular Physiological Effects of Veno-Arterial Extracorporeal Membrane Oxygenation Support During Cardiogenic Shock
NCT05426083
Recruiting
A Clinical Events Committee (CEC) will include Cardiac Surgery Professor and chief of cardiac surgery Rose Kelly MD, Professor of Medicine Ganesh Raveendran MD at the University of Minnesota who is the direction of Interventional Cardiology and Professor of Medicine at the University of Minnesota David Benditt. They will review and adjudicate serious and unexpected adverse events independently from the PI and co investigators.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/16/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Acute Coronary Syndrome, Cardiogenic Shock
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Enhancing Rural Health Via Cardiovascular Telehealth for Rural Patients Implementation (E-VICTORS)
NCT04617834
Recruiting
This pre-post study will evaluate the implementation of a cardiovascular telehealth platform, which will connect experts from the Wake Forest University Health Sciences (WFUHS) tertiary care center with Wilkes County Emergency Medical Services (WC-EMS) system, Wilkes Medical Center Emergency Department (ED), and The Wilkes County Health Department Public Health Community Clinic (PHCC) to improve cardiovascular care in this rural community.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/09/2023
Locations: Wilkes County Emergency Medical Services, Wilkesboro, North Carolina +3 locations
Conditions: Cardiovascular Diseases, Acute Coronary Syndrome
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