The state of Texas currently has 32 active clinical trials seeking participants for Dementia research studies. These trials are conducted in various cities, including Houston, Dallas, San Antonio and Austin.
Cognitive Outcomes of Brain Stimulation As a Later-in-Life Treatment
Recruiting
This is a pilot study being done to attempt to improve episodic memory problems in persons with mild cognitive impairment (MCI) or dementia. The pre-supplemental motor area (preSMA) and dorsal anterior cingulate cortex (dACC) have been shown to play a role in episodic memory and language retrieval. Prior studies have suggested that neurostimulation targeting this region can improve episodic memory and word recall. The purpose of this study is to examine the efficacy of high-definition transcrani... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
08/07/2023
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Mild Cognitive Impairment, Dementia, Amnestic Mild Cognitive Impairment - aMCI
Trial of Parkinson's And Zoledronic Acid
Recruiting
This home-based study is a randomized (1:1) placebo-controlled trial of a single infusion of zoledronic acid-5 mg (ZA) for the prevention of fractures in men and women aged 60 years and older with Parkinson's disease and parkinsonism with at least 2 years of follow-up. A total of 3500 participants will be enrolled and randomized in the United States. Participants, follow-up outcome assessors, and study investigators will be blinded to assigned study treatment. This trial is funded by the Nationa... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
07/24/2023
Locations: University of Texas Southwestern Medical Center, Dallas, Texas +3 locations
Conditions: Parkinson Disease, Osteoporosis, Parkinsonism, Parkinson's Disease and Parkinsonism, Atypical Parkinsonism, Progressive Supranuclear Palsy, Multiple System Atrophy, Vascular Parkinsonism, Dementia With Lewy Bodies
Priorities Aligned Deprescribing for Persons Living With Dementia and Their Caregiver
Recruiting
The purpose of this study is to compare patient priorities care (PPC) and usual care (UC) patients to identify differences in post-encounter medication changes, treatment burden (TBQ), and shared decision making in Older Patient Assessment of Chronic Illness Care (OPACIC), to understand PPC participant's sense-making and communication approaches related to deprescribing decisions in relation to the identified health priorities and to identify and categorize adverse drug withdrawal events (ADWEs)
Gender:
All
Ages:
55 years and above
Trial Updated:
07/24/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Dementia
Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia
Recruiting
Difficulties with speech and language are the first and most notable symptoms of primary progressive aphasia (PPA). While there is evidence that demonstrates positive effects of speech-language treatment for individuals with PPA who only speak one language (monolinguals), there is a significant need for investigating the effects of treatment that is optimized for bilingual speakers with PPA. This stage 2 efficacy clinical trial seeks to establish the effects of culturally and linguistically tail... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
06/28/2023
Locations: University of Texas at Austin, Austin, Texas
Conditions: Primary Progressive Aphasia, Dementia, Dementia, Frontotemporal, Alzheimer Disease, Neurodegenerative Diseases, Frontotemporal Lobar Degeneration, Apraxia, Motor, Dysarthria, Communication Disorders, Language Disorders, Speech Disorders, Neurocognitive Disorders, Aphasia, Bilingual Aphasia
Life Story Questionnaire and Physical Therapy Participation
Recruiting
The goal of this clinical trial is to see the effect of life story questionnaire (LSQ) on physical therapy participation in patients with dementia. The main question[s] it aims to answer are: What is the effect of LSQ usage on physical therapy participation in people with dementia? What is the effect of LSQ usage on depression in people with dementia? What is the effect of LSQ usage on the quality of life in people with dementia? The researcher will compare these effects between the interventio... Read More
Gender:
All
Ages:
Between 60 years and 89 years
Trial Updated:
05/26/2023
Locations: Peachtree Place (Dementia care facility), Weatherford, Texas
Conditions: Dementia Alzheimers
GamePlan4Care: Online Support for Family Caregivers
Recruiting
As the population of older adults grows, almost doubling in size from 2012 to 2040, so too will the need for family caregiving. Caregiving can lead to negative psychosocial outcomes such as depression, anxiety, and burden; social isolation and family conflict: financial strain due to costs of care; and some caregivers also experience negative health consequences. This project will test the value of GamePlan4Care (GP4C) an evidence-based, internet-enabled system capable of providing immediate, ta... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/15/2022
Locations: Alzheimer's Texas, Austin, Texas
Conditions: Dementia
Creating Physical Objects With 3D Printers to Stimulate Reminiscing for Memory Loss [2 R44 AG049548-02A1]
Recruiting
In 2013 an estimated 5 million people age 65 and older had Alzheimer's disease. Longer life spans and aging baby boomers will cause this number to grow rapidly. More than 50% of residents in assisted living and nursing homes have some form of dementia or cognitive impairment and the number is increasing every day. As a form of person-centered, non-pharmacological dementia care, Reminiscence Therapy (RT) holds considerable promise. Improvements in mood, quality of life, social interaction, cogni... Read More
Gender:
All
Ages:
All
Trial Updated:
04/18/2022
Locations: University of Texas Arlington, Arlington, Texas
Conditions: Dementia
On Site Sensors Monitoring Impacts of Cognitive Decline on ADLs
Recruiting
The purpose of this research is to compare the effectiveness of a continuous monitoring system to assess Activities of Daily Living (ADLs) over time compared to the traditional assessments used by medical professionals as Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD) progresses.
Gender:
All
Ages:
65 years and above
Trial Updated:
04/29/2021
Locations: Birkeland Current, Waco, Texas
Conditions: Dementia, Dementia Alzheimers