A Post Approval Study to Investigate the Efficacy of Daridorexant in Subjects With Insomnia and Comorbid Nocturia
NCT05597020
Recruiting
A post approval study to investigate the efficacy of daridorexant in subjects with insomnia and comorbid nocturia
Gender:
All
Ages:
55 years and above
Locations: Baylor College of Medicine, Houston, Texas +13 locations
Conditions: Insomnia Disorder, Nocturia
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National Adaptive Trial for PTSD Related Insomnia
NCT03668041
Recruiting
Many Veterans with posttraumatic stress disorder (PTSD) have trouble sleeping or have frequent nightmares. So far, no medication has been approved for treatment of insomnia in PTSD. The purpose of this research study is to find out if taking medications called trazodone, eszopiclone, or gabapentin can help decrease symptoms of insomnia in patients with PTSD. PTSD is a form of intense anxiety which sometimes results from severe trauma. Symptoms may include nightmares, flashbacks, troublesome memo... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Locations: VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX, Dallas, Texas +34 locations
Conditions: Insomnia
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404
Recruiting
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.
Gender:
All
Ages:
Between 0 years and 20 years
Locations: Dell Children's Medical Center of Central Texas, Austin, Texas +51 locations
Conditions: Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Hemophilia, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
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Effectiveness of Healthy Habits for Hospitalized Older Adults to Optimize Rehabilitation
NCT04269239
Recruiting
This study aims to evaluate behavioral interventions in conjunction with medical rehabilitation to promote functional health in patients recovering from orthopedic surgery. Half of the subjects in this study will be assigned to an intervention that meets with a study therapist to discuss implementing healthy habits. The other half of subjects will assigned to an intervention group that meets with a study therapists to discuss implementing healthy sleep habits. Both groups will undergo several ph... Read More
Gender:
All
Ages:
40 years and above
Locations: University of Texas Medical Branch, Galveston, Texas +2 locations
Conditions: Insomnia, Pain, Osteoarthritis, Knee, Osteoarthritis, Hip
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