The state of Texas currently has 6 active clinical trials seeking participants for Narcolepsy research studies. These trials are conducted in various cities, including Houston, Dallas, San Antonio and Austin.
Study of MK-6552 in Participants With Narcolepsy Type 1 (MK-6552-004)
NCT06179407
Recruiting
The purpose of this study is to evaluate the safety, efficacy, pharmacokinetics (PK), and pharmacodynamics (PD) of MK-6552 in participants with Narcolepsy Type 1 (NT1). Part 1 will evaluate safety, tolerability, and PK of MK-6552 after administration of ascending doses in a single day to support a dose level decision for Part 2. Part 2 will investigate the PD of MK-6552 after single-day and multiple-day administration. Participants who complete Part 1 and demonstrate that they are able to tolera... Read More
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
06/20/2024
Locations: FutureSearch Trials of Neurology ( Site 0004), Austin, Texas
Conditions: Narcolepsy
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A Switch Study From High-Sodium Oxybate to XYWAV to Evaluate Changes in Blood Pressure in Participants With Narcolepsy
NCT05869773
Recruiting
The aim of this study is to quantify the change in blood pressure when participants with narcolepsy treated with high-sodium oxybate are transitioned to XYWAV, a low-sodium oxybate. The results of this study may provide health care providers (HCPs), patients, and payers with important new information regarding BP changes related to differences in sodium content between available oxybates for the treatment of narcolepsy.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
06/18/2024
Locations: FutureSearch Trials of Neurology, Austin, Texas +1 locations
Conditions: Narcolepsy
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Child and Adolescent Registry for Participants With Narcolepsy
NCT04899947
Recruiting
CATNAP is a patient registry designed to improve the understanding of the natural history of narcolepsy in pediatric patients. Descriptive statistics on disease characteristics will be performed. The study has 16 active clinical sites and a virtual site that widens participation to anywhere in the United States. For more information about the study or to access the Online Patient Enrollment System, visit the CATNAP website: https://catnap.healthie.net/welcome or email catnap@pulseinfoframe.com.... Read More
Gender:
All
Ages:
17 years and below
Trial Updated:
05/14/2024
Locations: Texas Children's Hospital (Baylor College of Medicine), Houston, Texas
Conditions: Narcolepsy
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A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Narcolepsy Type 1 (ALKS 2680-201)
NCT06358950
Recruiting
The purpose of this research study is to assess the safety and efficacy of ALKS 2680 compared to placebo, including whether participants taking ALKS 2680 experience a greater decrease in sleepiness and a decrease in cataplexy ("sudden loss of muscle control"), compared to participants taking placebo alone.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/07/2024
Locations: Alkermes Investigational Site, San Antonio, Texas
Conditions: Narcolepsy Type 1
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Ph4 PSG Combined JZP258-407
NCT05875974
Recruiting
This study will assess the safety and efficacy of JZP258 (XYWAV) on sleepiness, polysomnography, and functional outcomes in patients with idiopathic hypersomnia (IH) or narcolepsy.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/29/2024
Locations: FutureSearch Trials of Neurology, Austin, Texas +2 locations
Conditions: Idiopathic Hypersomnia, Narcolepsy
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A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
NCT05816382
Recruiting
The main aim is to evaluate the safety and tolerability of TAK-861 on participants with type 1 and type 2 narcolepsy from previous parent studies, TAK-861-2001 (NCT05687903) and TAK-861-2002 (NCT05687916).
Gender:
All
Ages:
Between 16 years and 70 years
Trial Updated:
02/15/2024
Locations: Sleep Therapy and Research Center, San Antonio, Texas
Conditions: Narcolepsy Type 1, Narcolepsy Type 2
Register for Updates