The city of Dallas, Texas, currently has 14 active clinical trials seeking participants for Alzheimer's Disease research studies.
AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid
NCT04468659
Recruiting
The primary purpose of this study is to determine whether treatment with lecanemab is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Trial) and to determine whether treatment with lecanemab is superior to placebo in reducing brain amyloid accumulation as measured by amyloid positron emission tomography (PET) at 216 weeks of treatment (A3 Trial). This study will also evaluate the long-term safety and tolerabili... Read More
Gender:
All
Ages:
Between 55 years and 80 years
Trial Updated:
02/06/2024
Locations: University of Texas, Southwestern MC at Dallas, Dallas, Texas
Conditions: Preclinical Alzheimer's Disease, Early Preclinical Alzheimer's Disease
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Noninvasive Brain Stimulation in Mild Cognitive Impairment and Dementia
NCT05270408
Recruiting
The research objective of this study is to examine the efficacy of HD-tDCS to the preSMA/DACC region and its influence on verbal episodic memory in patients with MCI or dementia after 10 sessions of HD-tDCS. There will be three treatment arms: two active HD-tDCS (1 mA or 2 mA) and a sham group. A verbal episodic memory task will be completed at baseline, immediately following the last HD-tDCS session, and a 2-month follow-up.
Gender:
All
Ages:
50 years and above
Trial Updated:
09/26/2023
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Alzheimer Disease, Mild Cognitive Impairment, Dementia
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