Dallas, TX Clinical Trials

A listing of Dallas, TX Clinical Trials actively recruiting patient volunteers.

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1571 trials found

Prospective Evaluation of Neurocognition in Patients Undergoing Transcatheter Aortic Valve Replacement

NCT05614986

This trail is for patients with mild cognitive impairment (MCI) who are receiving a transcatheter aortic valve replacement (TAVR). We will assess changes in neurocognition following TAVR with the 5 minute Montreal Cognitive Assessment (mini MoCA) when comparing pre procedure with post procedure assessments.

Conditions: Mild Cognitive Impairment, Aortic Stenosis

Atacicept in Subjects With Active Lupus Nephritis (COMPASS)

NCT05609812

The objective of the study is to evaluate the effect of atacicept compared to placebo on changes to renal response in adult subjects with LN.

Conditions: Lupus Nephritis (LN)

Pediatric Cervical Spine Clearance: A Multicenter Prospective Observational Study

NCT05608460

A prospective multicenter observational study, led by Dr. Katie Russell of Intermountain Primary Children's Hospital, that will examine the sensitivity, specificity, negative, and positive predictive values of CT scan and plain films in diagnosing cervical spine injury that requires treatment. This study is funded by the Primary Children's Hospital foundation.

Conditions: Cervical Spine Fracture

Evaluating the Efficacy of Pathways Parent-Mediated Early Autism Intervention on Social Attention and Language

NCT05604326

The goal of this clinical trial is to compare the efficacy of Pathways parent-mediated early autism intervention (Pathways) and a parent education intervention (PEI) delivered to culturally and linguistically diverse families with children 12-42 months of age suspected of or diagnosed with autism. Question 1: Is Pathways more effective than a PEI at (a) fostering the development of social orienting, joint attention, and social communication and language in children with a research diagnosis of ...

Conditions: Autism Spectrum Disorder
Phase: Not Applicable

A Drug Interaction Study of LY3871801 in Healthy Participants

NCT05602675

The main purpose of this study is to determine the effect of LY3871801 when administered orally on the levels of methotrexate (part 1), drug cocktail (warfarin, dextromethorphan, and midazolam) and repaglinide (part 2) in the blood stream when administered orally in healthy participants. The information about any adverse effects experienced will be collected and the tolerability of LY3871801 will also be evaluated. The study may last up to approximately 25 days for each participant.

Conditions: Healthy

Dry Needling and Shoulder Muscle Blood Flow, Motions, and Pain Sensitivity in Individuals With Shoulder Pain

NCT05596240

Shoulder pain is one of the most common reasons people consult with their primary health care provider, and 40-50% of these patients with shoulder pain continued to complain of persistent symptoms after 6 to 12 months. It has been suggested that the presence of myofascial trigger points (MTrPs) may contribute to the chronicity of shoulder symptoms. An MTrP is a hyperirritable taut band of tissue within a muscle that produces pain when stimulated MTrPs are common in patients with shoulder disorde ...

Conditions: Dry Needling, Shoulder Pain
Phase: Not Applicable

Coping, Perceived Meaning, Joy, Horizontal Civility at Work

NCT05595057

The aim of this study is to assess and describe employee characteristics associated with perceived horizontal inter-collegial workplace uncivil behavior within nursing services, and identify any relationships with meaning and joy in work (MJW), and assess job satisfaction.

Conditions: Workplace Incivility, Joy, Self Efficacy

Evaluation of the Clinical Impact of Corticosteroid Duration on SARS-CoV-2 (COVID-19 WHO)

NCT05595031

The purpose of this project is to evaluate the clinical impact of the use of glucocorticoids beyond 10 days for patients with critical COVID-19 at MDMC.

Conditions: Covid 19

Outcomes Using MARS for Patients With ALF

NCT05594953

Retrospective chart review will be conducted on patients at Methodist Dallas Medical Center, meeting the inclusion criteria from January 1, 2019 to December 15, 2020 to determine the transplant free survival and overall survival and other secondary outcome measures.

Conditions: Alcoholic Hepatitis, Acute Liver Failure

Pharmacological Modulation of Brain Oscillations in Memory Processing

NCT05594017

The goal of this study is to learn about the effects of scopolamine (an anticholinergic drug) on areas of the brain involved in memory, and changes it may have on brain activity. The investigators will do this by testing epileptic patients who are already undergoing intracranial surgery for seizure monitoring, and measuring the activity from the brain areas being assessed. The main questions it aims to answer are 1) whether scopolamine changes memory activity solely at encoding (the time when t ...

Conditions: Epilepsy, Seizures, Cognitive Impairment, Mild, Memory Disorders, Memory Loss
Phase: Early Phase 1

Head and Neck Trauma Registry, Protocol ID: 032.MBSI.2021.D

NCT05592899

This is a retrospective registry dataset of all adults who presented with cervical and/or skull base fractures or a subdural hematoma at Methodist Dallas Medical Center (MDMC) and had consults to the neurological surgery department beginning in January of 2016, and continuing until a statistically significant number of cases are obtained.

Conditions: Craniocerebral Trauma

Study of Novel Antiretrovirals in Participants With HIV-1

NCT05585307

Master protocol: The goal of this master (umbrella) clinical trial study is to learn how novel antiretrovirals affect the HIV-1 infection in people living with HIV (PWH). The safety and how well the study drugs are tolerated will be determined by using physical exams, laboratory tests, and any symptoms or problems a participant might experience during the study. Substudy-01 (GS-US-544-5905-01) will evaluate GS-5894 in people with HIV PWH.

Conditions: HIV-1-infection