There are currently 343 clinical trials in Fort Worth, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including Cook Children's Medical Center, GSK Investigational Site, Cook Children's Medical Center - Fort Worth and UT Southwestern/Simmons Cancer Center-Fort Worth. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)
NCT04174157
Recruiting
Spinal muscular atrophy (SMA) is a neurogenetic disorder caused by a loss or mutation in the survival motor neuron 1 gene (SMN1) on chromosome 5q13, which leads to reduced SMN protein levels and a selective dysfunction of motor neurons. SMA is an autosomal recessive, early childhood disease with an incidence of 1:10,000 live births. SMA is the leading cause of infant mortality due to genetic diseases. Until recently, the mainstay of treatment for these patients was supportive medical care. Howe... Read More
Gender:
All
Ages:
All
Trial Updated:
04/18/2023
Locations: Cook Children's, Fort Worth, Texas
Conditions: Spinal Muscular Atrophy (SMA)
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IHT for Mild Cognitive Impairment
NCT05495087
Recruiting
This phase I clinical trial will examine the safety and efficacy of intermittent hypoxia training (IHT) for up to 12 weeks to treat subjects with mild cognitive impairment (MCI).
Gender:
All
Ages:
Between 55 years and 80 years
Trial Updated:
04/03/2023
Locations: University of North Texas Health Science Center, Fort Worth, Texas
Conditions: Mild Cognitive Impairment, Memory Impairment
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A Study Evaluating an Advanced Pneumatic Compression Device Versus Usual Care for Treatment of Head and Neck Lymphedema
NCT04797390
Recruiting
To compare the effectiveness of an APCD to Usual Care in the management of lymphedema and fibrosis (LEF) in head and neck cancer (HNC) survivors.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2023
Locations: Advanced Head & Neck Rehabilitation Center of Texas, Fort Worth, Texas
Conditions: Lymphedema, Lymphedema of Face, Lymphedema, Secondary, Lymphedema Due to Radiation, Lymphedema; Surgical
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Randomized Therapy In Status Epilepticus
NCT04391569
Recruiting
This study will evaluate the effectiveness and safety of an investigational product (IP), intravenous (IV) ganaxolone, to treat participants with status epilepticus (SE).
Gender:
All
Ages:
12 years and above
Trial Updated:
02/22/2023
Locations: Marinus Research Site, Fort Worth, Texas
Conditions: Status Epilepticus
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A Study of Therapeutic Iobenguane (131-I) and Vorinostat for Recurrent or Progressive High-Risk Neuroblastoma Subjects
NCT03561259
Recruiting
The purpose of this study is to evaluate the efficacy and safety of 131I-MIBG in combination with Vorinostat in patients with Recurrent or Progressive neuroblastoma
Gender:
All
Ages:
1 year and above
Trial Updated:
02/15/2023
Locations: Cook Children's Hematology/Oncology Center, Fort Worth, Texas
Conditions: Neuroblastoma, Neuroectodermal Tumors, Neoplasms
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Preventing Opioid Use Among Justice-involved Youth as They Transition to Adulthood Leveraging Safe Adults (LeSA)
NCT04678960
Recruiting
Across the US, substance use is a significant public health concern, with juvenile justice (JJ)-involved youth representing a particularly vulnerable population. The current study proposes to adapt and test an intervention Trust-based Relational Intervention® (TBRI®) for preventing initiation and/or escalation of opioid misuse among older adolescents involved in the JJ system. Successful completion of study aims will provide information on TBRI's utility for older JJ adolescents, barriers and fa... Read More
Gender:
All
Ages:
Between 15 years and 20 years
Trial Updated:
01/20/2023
Locations: Texas Juvenile Justice Department - Willoughby House, Fort Worth, Texas
Conditions: Opioid Use, Substance Use
Register for Updates
GABA Biomarkers in Dravet Syndrome
NCT05651204
Recruiting
This study will non-invasively obtain levels of GABA in the brain of children with SCN1A+DS and neurodeveloping children through evoked and induced cortical responses, correlate them with the BOLD responses, and with the levels of GABA in their blood.
Gender:
All
Ages:
18 years and below
Trial Updated:
12/13/2022
Locations: Cook Children's Medical Center, Fort Worth, Texas
Conditions: Dravet Syndrome
Register for Updates
A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)
NCT02817633
Recruiting
This is a first-in-human study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022. The study will be conducted in 2 parts with Part 1 consisting of dose escalation and Part 2 dose expansion. Part 1 will determine the recommended Phase 2 dose (RP2D) of TSR-022 and Part 2 will evaluate the antitumor activity of TSR-022 in combination with TSR-042 or docetaxel and as monotherapy
Gender:
All
Ages:
18 years and above
Trial Updated:
12/09/2022
Locations: GSK Investigational Site, Fort Worth, Texas
Conditions: Neoplasms
Register for Updates
Fluorodopa F 18 in Congenital Hyperinsulinism and Insulinoma
NCT02021604
Recruiting
Low blood sugars are known to cause brain damage in newborn babies. One of the most common causes of low blood sugars persisting beyond the new born period is a condition called congenital hyperinsulinism (HI). This is a disease whereby the pancreas secretes too much insulin and causes low blood sugars. Twenty to forty percent of these babies will have brain damage. There are two forms of this disease. In one form only a small part of the pancreas makes too much insulin (focal HI) and in the oth... Read More
Gender:
All
Ages:
18 years and below
Trial Updated:
12/08/2022
Locations: Cook Children's Medical Center, Fort Worth, Texas
Conditions: Congenital Hyperinsulinism, Insulinoma
Register for Updates
Prospective Evaluation of Neurocognition in Patients Undergoing Transcatheter Aortic Valve Replacement
NCT05614986
Recruiting
This trail is for patients with mild cognitive impairment (MCI) who are receiving a transcatheter aortic valve replacement (TAVR). We will assess changes in neurocognition following TAVR with the 5 minute Montreal Cognitive Assessment (mini MoCA) when comparing pre procedure with post procedure assessments.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/07/2022
Locations: Baylor Scott & White All Saints at Fort Worth, Fort Worth, Texas
Conditions: Mild Cognitive Impairment, Aortic Stenosis
Register for Updates
2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C
NCT04012996
Recruiting
A multi-center, prospective, randomized, controlled comparison of the prodisc C SK and prodisc C Vivo to the control, a similar, legally marketed total disc replacement device in subjects with symptomatic cervical disc disease (SCDD).
Gender:
All
Ages:
Between 18 years and 69 years
Trial Updated:
10/27/2022
Locations: DFW Center for Spinal Disorders, Fort Worth, Texas
Conditions: Symptomatic Cervical Disc Disease
Register for Updates
A Study to Evaluate LB1148 for Return of Gastrointestinal Function and Adhesions in Subjects Undergoing Bowel Resection
NCT02836470
Recruiting
The purpose of this study is to establish preliminary evidence of the efficacy, safety, and tolerability of LB1148 for the treatment of post-operative ileus and intra-abdominal adhesions in subjects undergoing elective bowel resection.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
10/27/2022
Locations: Site 316, Fort Worth, Texas
Conditions: Ileus, Post-Operative Adhesions
Register for Updates