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                    Carboplatin Treatment Options in Ohio
A collection of 550 research studies where Carboplatin is the interventional treatment. These studies are located in the Ohio, United States. Carboplatin is used for conditions such as Non-Small Cell Lung Cancer, Ovarian Cancer and Lung Cancer.
            481 - 492 of 550
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                Chronic Kidney Disease (CKD) Clinical Study
            
        Recruiting
            
        A clinical study for people that suffer with Chronic Kidney Disease (CKD)
    
    
                            Conditions: 
                                    
        
            
                        Chronic Kidney Disease (CKD)
                    
                                    
                
                                    Carboplatin, Paclitaxel, and Radiation Therapy With or Without Thalidomide in Patients With Stage III Non-small Cell Lung Cancer
                                
            
            
        Terminated
                            
            
                This randomized phase III trial is studying carboplatin, paclitaxel, radiation therapy, and thalidomide to see how well they work compared to carboplatin, paclitaxel, and radiation therapy alone in treating patients with newly diagnosed stage III non-small cell lung cancer. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Thalidomide may stop the growth of non-small cell lung cancer by stopping blood flow to the tumor. It is not yet kno...  Read More             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                05/29/2014
            
            Locations: Akron City Hospital, Akron, Ohio  +36 locations         
        
        
            Conditions: Lung Cancer
        
            
        
    
                
                                    Carboplatin, Paclitaxel, and Bevacizumab With or Without Erlotinib Hydrochloride in Treating Non-Smokers With Advanced Non-Small Cell Lung Cancer
                                
            
            
        Terminated
                            
            
                This randomized phase II trial studies how well carboplatin, paclitaxel, and bevacizumab work with or without erlotinib hydrochloride in treating non-smokers with advanced non-small cell lung cancer. Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tum...  Read More             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                05/23/2014
            
            Locations: Mercy Medical Center, Canton, Ohio  +6 locations         
        
        
            Conditions: Recurrent Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer
        
            
        
    
                
                                    Study of Combretastatin and Paclitaxel/Carboplatin in the Treatment of Anaplastic Thyroid Cancer
                                
            
            
        Terminated
                            
            
                The purpose of the study is to determine the safety and efficacy of combretastatin combined with paclitaxel and carboplatin in the treatment of anaplastic thyroid cancer (ATC).             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                05/12/2014
            
            Locations: Ireland Cancer Center/Division od Hematology, Cleveland, Ohio         
        
        
            Conditions: Anaplastic Thyroid Cancer
        
            
        
    
                
                                    A Study for Participants With Recurrent or Metastatic Squamous Cell Head and Neck Cancer
                                
            
            
        Completed
                            
            
                The purpose of this study is to look for an improvement in progression free survival with the combination of pemetrexed, carboplatin (or cisplatin) and cetuximab in participants with recurrent or metastatic squamous cell carcinoma of the head and neck.             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                04/18/2014
            
            Locations: For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Cincinnati, Ohio         
        
        
            Conditions: Head and Neck Neoplasms
        
            
        
    
                
                                    Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors
                                
            
            
        Completed
                            
            
                RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctors to give higher doses of chemotherapy drugs and kill more tumor cells.
PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy plus peripheral stem cell transplantation in treating infants with malignant brain or spinal cord tumors.             
        
        
    Gender:
                ALL
            Ages:
                2 years and below
            Trial Updated:
                03/27/2014
            
            Locations: Akron Children's Hospital, Akron, Ohio  +6 locations         
        
        
            Conditions: Brain Tumors, Central Nervous System Tumors, Neuroblastoma, Sarcoma
        
            
        
    
                
                                    Radiation Therapy Plus Carboplatin and Lobradimil in Treating Children With Newly Diagnosed Brain Stem Gliomas
                                
            
            
        Completed
                            
            
                RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as carboplatin and lobradimil may make the tumor cells more sensitive to radiation therapy.
PURPOSE: Phase I trial to study the effectiveness of combining radiation therapy with carboplatin and lobradimil in treating children who have newly diagnosed brain stem gliomas.             
        
        
    Gender:
                ALL
            Ages:
                Between 3 years and 21 years
            Trial Updated:
                02/19/2014
            
            Locations: Children's Hospital Medical Center - Cincinnati, Cincinnati, Ohio         
        
        
            Conditions: Brain and Central Nervous System Tumors
        
            
        
    
                
                                    Cetuximab and Carboplatin in Treating Patients With Recurrent Ovarian Epithelial Cancer or Primary Peritoneal Cancer
                                
            
            
        Completed
                            
            
                RATIONALE: Monoclonal antibodies such as cetuximab can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Drugs used in chemotherapy such as carboplatin work in different ways to stop tumor cells from dividing so they stop growing or die. Combining cetuximab with carboplatin may kill more tumor cells.
PURPOSE: This phase II trial is studying how well giving cetuximab together with carboplatin works in treating patients with recurren...  Read More             
        
        
    Gender:
                FEMALE
            Ages:
                18 years and above
            Trial Updated:
                02/12/2014
            
            Locations: Charles M. Barrett Cancer Center at University Hospital, Cincinnati, Ohio  +3 locations         
        
        
            Conditions: Ovarian Cancer, Primary Peritoneal Cavity Cancer
        
            
        
    
                
                                    Vinblastine and Carboplatin in Treating Young Patients With Newly Diagnosed or Recurrent Low-Grade Glioma
                                
            
            
        Completed
                            
            
                RATIONALE: Drugs used in chemotherapy, such as vinblastine and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of vinblastine when given together with carboplatin in treating young patients with newly diagnosed or recurrent low-grade glioma.             
        
        
    Gender:
                ALL
            Ages:
                21 years and below
            Trial Updated:
                02/11/2014
            
            Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio         
        
        
            Conditions: Brain and Central Nervous System Tumors, Neurofibromatosis Type 1
        
            
        
    
                
                                    Study of Everolimus With Paclitaxel and Carboplatin in Patients With Metastatic Melanoma
                                
            
            
        Completed
                            
            
                Based on data demonstrating synergy between paclitaxel and mammalian target of rapamycin (mTOR) inhibition, the investigators propose that the addition of everolimus to paclitaxel with carboplatin should lead to improvements in efficacy as measured by progression-free survival and response rate.             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                02/10/2014
            
            Locations: Oncology Hematology Care, Cincinnati, Ohio         
        
        
            Conditions: Metastatic Melanoma
        
            
        
    
                
                                    Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer
                                
            
            
        Completed
                            
            
                RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more tumor cells
PURPOSE: Randomized phase II trial to compare the effectiveness of three different regimens of combining paclitaxel and carboplatin plus radiation therapy in treating patients who have stage III non-small cell lung cancer that cannot be remov...  Read More             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                01/08/2014
            
            Locations: University Hospitals of Cleveland, Cleveland, Ohio         
        
        
            Conditions: Lung Cancer
        
            
        
    
                
                                    Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer
                                
            
            
        Unknown
                            
            
                RATIONALE: Drugs used in chemotherapy use different ways to stop tumors from dividing so they stop growing or die. Chemoprotective drugs, such as amifostine, may protect normal cells from the side effects of chemotherapy.
PURPOSE: Phase I trial to study the effectiveness of amifostine plus combination chemotherapy in treating patients with advanced cancer.             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                12/18/2013
            
            Locations: Cleveland Clinic Cancer Center, Cleveland, Ohio         
        
        
            Conditions: Chronic Myeloproliferative Disorders, Drug/Agent Toxicity by Tissue/Organ, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Precancerous Condition, Unspecified Adult Solid Tumor, Protocol Specific
        
            
        
    
                
                                    Combination Chemotherapy With or Without Etoposide Followed By an Autologous Stem Cell Transplant in Treating Young Patients With Previously Untreated Malignant Brain Tumors
                                
            
            
        Unknown
                            
            
                RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. A bone marrow or peripheral stem cell transplant using stem cells from the patient may be able to replace blood-forming cells that were destroyed by chemotherapy. This may allow more chemotherapy to be given so that more tumor cells are killed.
PURPOSE: This phase III trial is studying how well giving combination chemotherapy with or with...  Read More             
        
        
    Gender:
                ALL
            Ages:
                10 years and below
            Trial Updated:
                12/17/2013
            
            Locations: Rainbow Babies and Children's Hospital, Cleveland, Ohio  +4 locations         
        
        
            Conditions: Brain and Central Nervous System Tumors
        
            
        
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