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Carboplatin Treatment Options
A collection of 1668 research studies where Carboplatin is the interventional treatment. These studies are located in the United States. Carboplatin is used for conditions such as Non-Small Cell Lung Cancer, Ovarian Cancer and Lung Cancer.
1321 - 1332 of 1668
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Trial of Poor Performance Status Patients (ToPPS)
Completed
The purpose of this trial is to evaluate three treatment regimens in patients with stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) with a performance status of 2 and who were not previously treated.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2015
Locations: Mayo Clinic - AZ, Scottsdale, Arizona +26 locations
Conditions: Non Small Cell Lung Cancer
Polyglutamate Paclitaxel and Carboplatin in Treating Patients With Ovarian Epithelial, Peritoneal, or Fallopian Tube Cancer
Completed
This phase I trial is studying the side effects and best dose of polyglutamate paclitaxel when given together with carboplatin in treating patients with ovarian epithelial, peritoneal, or fallopian tube cancer. Drugs used in chemotherapy such as polyglutamate paclitaxel and carboplatin use different ways to stop tumor cells from dividing so they stop growing or die. Polyglutamate paclitaxel may be able to deliver the drug directly to tumor cells while leaving normal cells undamaged. Combining po... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/07/2015
Locations: Gynecologic Oncology Group, Philadelphia, Pennsylvania
Conditions: Fallopian Tube Carcinoma, Malignant Ovarian Mixed Epithelial Tumor, Ovarian Brenner Tumor, Ovarian Clear Cell Cystadenocarcinoma, Ovarian Endometrioid Adenocarcinoma, Ovarian Mucinous Cystadenocarcinoma, Ovarian Serous Cystadenocarcinoma, Primary Peritoneal Carcinoma, Stage III Ovarian Cancer, Stage IV Ovarian Cancer, Undifferentiated Ovarian Carcinoma
High-Dose Chemotherapy Plus Autologous Stem Cell Transplantation Compared With Intermediate-Dose Chemotherapy Plus Autologous Stem Cell Transplantation With or Without Isotretinoin in Treating Young Patients With Recurrent High-Grade Gliomas
Completed
RATIONALE: Drugs used in chemotherapy, such as carboplatin, thiotepa, and etoposide, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with autologous stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. Isotretinoin may be effective in preventing recurrence of glioma. It is not yet known which regimen of chemotherapy plus autologous stem cell transplantation with or without... Read More
Gender:
ALL
Ages:
20 years and below
Trial Updated:
05/06/2015
Locations: Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas +58 locations
Conditions: Brain Tumor, Central Nervous System Tumor
Evaluation of Non-cytotoxic Suramin as a Chemosensitizer in Non-small Cell Lung Cancer
Terminated
The purpose of this study is to evaluate the benefit of adding suramin at a non-cytotoxic dose to carboplatin and docetaxel regimen in the treatment of chemo-naïve patients with non-small cell lung cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/04/2015
Locations: John H Stroger Jr Hospital of Cook County, Chicago, Illinois +1 locations
Conditions: Non-small Cell Lung Cancer
Panitumumab, Gemcitabine and Carboplatin in Triple-Negative Metastatic Breast Cancer
Completed
In this Phase II trial, the investigators will evaluate the combination of gemcitabine, carboplatin, and panitumumab in the treatment of patients with metastatic triple-negative breast cancer. In addition, to assess the efficacy of this combination, tumor tissue will be examined for the presence of various markers, including K-ras and PI3K-activating mutations, EGFR, PTEN, and p53. Correlation of tumor response with marker expression may define a patient subset that is particularly responsive to... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/28/2015
Locations: Los Robles, Thousand Oaks, California +16 locations
Conditions: Metastatic Breast Cancer
Study of Gemcitabine/Carboplatin/Bevacizumab to Treat Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Completed
The purpose of this study is to test the effectiveness, safety and tolerability of the drug combination: gemcitabine, carboplatin and bevacizumab in patients that have been diagnosed with platinum sensitive recurrent ovarian cancer, fallopian tube or primary peritoneal cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/28/2015
Locations: The Ohio State University & James Cancer Hospital, Columbus, Ohio
Abraxane and RT for Non-Small Cell Lung Cancer (NSCLC)
Withdrawn
For patients with stage III Lung Cancer, We propose one cycle chemotherapy using Abraxane and Carboplatin, followed by pulsed low-dose sensitizing Abraxane chemotherapy and daily Radiation. This will be followed by more hi-dose chemotherapy. We anticipate this regimen to target early distant microscopic spread by using one cycle of chemotherapy prior to radiation, and to achieve control of the disease in the lung by combining pulsed low-dose sensitizing Abraxane, with radiation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/24/2015
Locations: University of Rochester, Medical Center, Rochester, New York
Conditions: Non-small Cell Lung Cancer, Stage III
Phase II Docetaxel / Carboplatin / XRT + Surgical Resection in Stage III NSCLC
Terminated
The purpose of this study is to assess how well this particular combination of chemotherapy, radiation and surgery works to help people with locally advanced lung cancer, how well PET scans indicates whether someone has responded to chemotherapy and radiation, and gene expression patterns related to outcomes in patients with locally advanced lung cancer who receive this treatment regimen.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/21/2015
Locations: Stanford University School of Medicine, Stanford, California
Conditions: Lung Cancer, Carcinoma, Non-Small-Cell Lung
First-line Treatment Of Subjects With Extensive Disease Small Cell Lung Cancer With Weekly Hycamtin And Paraplatin
Completed
This study was designed to find the safest and most effective dose of a combination of two chemotherapy drugs, Hycamtin® (topotecan) and Paraplatin® (carboplatin), in people with extensive disease small cell lung cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/20/2015
Locations: GSK Investigational Site, Tucson, Arizona +12 locations
Conditions: Lung Cancer, Small Cell
Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Patients With Metastatic Melanoma
Completed
The purpose of this Phase 2 study is to investigate whether intravenous administration of REOLYSIN therapeutic virus in combination with paclitaxel and carboplatin is effective and safe in the treatment of metastatic melanoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/08/2015
Locations: Cancer Therapy & Research Center at UTHSCSA, San Antonio, Texas
Conditions: Metastatic Melanoma
Trial of Paclitaxel/Carboplatin + PF-3512676 vs Paclitaxel/Carboplatin Alone in Patients With Advanced Non-Small Cell Lung Cancer
Terminated
To assess the efficacy and safety of PF-3512676 administered in combination with paclitaxel/carboplatin chemotherapy as first-line treatment in patients with locally advanced or metastatic Non-Small-Cell Lung Cancer (NSCLC) and to compare it to the efficacy and safety of paclitaxel
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/10/2015
Locations: Pfizer Investigational Site, Little Rock, Alaska +190 locations
Conditions: Carcinoma, Non-Small-Cell Lung
Carboplatin as a Radiosensitizer in Treating Childhood Ependymoma
Terminated
This is a phase II study evaluating the feasibility of concurrent carboplatin given with focal radiation therapy in children age 12 months to \< 21 years with newly diagnosed localized ependymoma who have no or minimal residual disease post-operatively (\< 0.5 cm). The hypothesis is that utilizing carboplatin as a radiosensitizer is feasible and tolerable and may improve event-free survival (EFS) and minimize local recurrences as compared to historic controls. Following a neurosurgical resection... Read More
Gender:
ALL
Ages:
Between 12 months and 21 years
Trial Updated:
02/27/2015
Locations: Children's Memorial Hospital, Chicago, Illinois
Conditions: Ependymoma
1321 - 1332 of 1668