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                    Cyclophosphamide Treatment Options in Plano, TX
A collection of 11 research studies where Cyclophosphamide is the interventional treatment. These studies are located in the Plano, TX. Cyclophosphamide is used for conditions such as Breast Cancer, Lymphoma and Leukemia.
            1 - 11 of 11
        
        
    Featured Trial
                
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                            Conditions: 
                                    
        
            
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                        Overweight and Obesity
                    
                                    
                        Obesity
                    
                                    
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                                    Featured Trial
                
                Stroke Clinical Study
            
        Recruiting
            
        A clinical study for people that suffer with Stroke
    
    
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                        Stroke
                    
                                    Featured Trial
                
                Chronic Kidney Disease (CKD) Clinical Study
            
        Recruiting
            
        A clinical study for people that suffer with Chronic Kidney Disease (CKD)
    
    
                            Conditions: 
                                    
        
            
                        Chronic Kidney Disease (CKD)
                    
                                    
                
                                    A Study of Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer
                                
            
            
        Completed
                            
            
                This randomized, double-blind, placebo-controlled, two-arm study will assess the safety and efficacy of pertuzumab in addition to chemotherapy plus trastuzumab as adjuvant therapy in participants with operable HER2-positive primary breast cancer. This study will be carried out in collaboration with the Breast International Group (BIG).             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                07/11/2025
            
            Locations: Texas Oncology-Medical City Dallas, Dallas, Texas  +10 locations         
        
        
            Conditions: Breast Cancer
        
            
        
    
                
                                    Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)
                                
            
            
        Active Not Recruiting
                            
            
                The purpose of this study is to assess the efficacy and safety of pembrolizumab (MK-3475) versus placebo in combination with neoadjuvant (pre-surgery) chemotherapy and adjuvant (post-surgery) endocrine therapy in the treatment of adults who have high-risk early-stage estrogen receptor-positive, human epidermal growth factor receptor 2-negative (ER+/HER2-) breast cancer.
The primary study hypotheses are: 1) pembrolizumab is superior to placebo, both in combination with the protocol-specified neo...  Read More             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                07/08/2025
            
            Locations: Texas Oncology-Austin Central ( Site 8004), Austin, Texas  +6 locations         
        
        
            Conditions: Breast Cancer
        
            
        
    
                
                                    Chemotherapy With or Without Trastuzumab After Surgery in Treating Women With Invasive Breast Cancer
                                
            
            
        Completed
                            
            
                This randomized phase III clinical trial studies chemotherapy with or without trastuzumab after surgery to see how well they work in treating women with invasive breast cancer. Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving more than one drug (combination chemotherapy) and giving chemotherapy after surgery may kill more tumor cells. Monoclonal antibodies,...  Read More             
        
        
    Gender:
                FEMALE
            Ages:
                18 years and above
            Trial Updated:
                06/25/2025
            
            Locations: Hendrick Medical Center, Abilene, Texas  +43 locations         
        
        
            Conditions: HER2/Neu Positive, Progesterone Receptor Positive, Recurrent Breast Carcinoma, Stage IA Breast Cancer AJCC v7, Stage IB Breast Cancer AJCC v7, Stage IIA Breast Cancer AJCC v6 and v7, Stage IIB Breast Cancer AJCC v6 and v7, Stage IIIA Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7
        
            
        
    
                
                                    Study of Safety and Efficacy of Pembrolizumab and Chemotherapy in Participants With Newly Diagnosed Classical Hodgkin Lymphoma (cHL) (MK-3475-C11/KEYNOTE-C11)
                                
            
            
        Completed
                            
            
                The purpose of this study is to evaluate the safety and efficacy of pembrolizumab (MK-3475) monotherapy, followed by chemotherapy, followed by pembrolizumab consolidation. The primary hypothesis of the study is that the complete response (CR) rate at the end of study intervention according to Lugano 2014 response criteria is higher than conventional chemotherapy.             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                05/23/2025
            
            Locations: Texas Oncology-Plano East ( Site 0020), Plano, Texas         
        
        
            Conditions: Classical Hodgkin Lymphoma
        
            
        
    
                
                                    Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors
                                
            
            
        Active Not Recruiting
                            
            
                A study to learn about safety and find out maximum tolerable dose of palbociclib given in combination with chemotherapy (temozolomide with irinotecan or topotecan with cyclophosphamide) in children, adolescents and young adults with recurrent or refractory solid tumors (phase 1). Neuroblastoma tumor specific cohort to further evaluate antitumor activity of palbociclib in combination with topotecan and cyclophosphamide in children, adolescents, and young adults with recurrent or refractory neurob...  Read More             
        
        
    Gender:
                ALL
            Ages:
                Between 2 years and 20 years
            Trial Updated:
                01/13/2025
            
            Locations: Children's Blood and Cancer Center, Austin, Texas  +6 locations         
        
        
            Conditions: Solid Tumors, Ewing Sarcoma, Rhabdoid Tumor, Rhabdomyosarcoma, Neuroblastoma, Medulloblastoma, Diffuse Intrinsic Pontine Glioma
        
            
        
    
                
                                    Study of Pembrolizumab (MK-3475) Plus Chemotherapy vs Placebo Plus Chemotherapy as Neoadjuvant Therapy and Pembrolizumab vs Placebo as Adjuvant Therapy in Participants With Triple Negative Breast Cancer (TNBC) (MK-3475-522/KEYNOTE-522)
                                
            
            
        Active Not Recruiting
                            
            
                The purpose of this study is to evaluate the efficacy and safety of pembrolizumab (MK-3475) plus chemotherapy vs placebo plus chemotherapy as neoadjuvant therapy and pembrolizumab vs placebo as adjuvant therapy in participants who have triple negative breast cancer (TNBC).
After a screening phase of approximately 28 days, each participant will receive neoadjuvant study treatment (Pembrolizumab + Chemotherapy OR Placebo + Chemotherapy) based on the randomization schedule for approximately 24 wee...  Read More             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                01/08/2025
            
            Locations: Texas Oncology-Austin Central ( Site 8005), Austin, Texas  +10 locations         
        
        
            Conditions: Triple Negative Breast Neoplasms
        
            
        
    
                
                                    Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer
                                
            
            
        Active Not Recruiting
                            
            
                This randomized phase III trial studies how well doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carboplatin work in treating patients with triple-negative breast cancer. Drugs used in chemotherapy, such as doxorubicin hydrochloride, cyclophosphamide, paclitaxel, and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whethe...  Read More             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                05/31/2024
            
            Locations: Hendrick Medical Center, Abilene, Texas  +47 locations         
        
        
            Conditions: Breast Adenocarcinoma, Estrogen Receptor Negative, HER2/Neu Negative, Progesterone Receptor Negative, Stage IB Breast Cancer, Stage IIA Breast Cancer, Stage IIB Breast Cancer, Stage IIIA Breast Cancer, Stage IIIC Breast Cancer, Triple-Negative Breast Carcinoma
        
            
        
    
                
                                    A Clinical Trial Comparing the Combination of TC Plus Bevacizumab to TC Alone and to TAC for Women With Node-Positive or High-Risk Node-Negative, HER2-Negative Breast Cancer
                                
            
            
        Completed
                            
            
                The main purpose of this study is to learn if adding bevacizumab to standard treatment with chemotherapy (docetaxel, doxorubicin, and cyclophosphamide) for early stage HER2-negative breast cancer will prevent breast cancer from returning. A second purpose of this study is to learn if adding bevacizumab to treatment with chemotherapy will help women with HER2-negative breast cancer live longer. The researchers also want to learn about the side effects of the combination of drugs used in this stud...  Read More             
        
        
    Gender:
                FEMALE
            Ages:
                Between 18 years and 70 years
            Trial Updated:
                04/13/2022
            
            Locations: Texas Cancer Center - Abilene South, Abilene, Texas  +56 locations         
        
        
            Conditions: Breast Cancer
        
            
        
    
                
                                    Docetaxel and Cyclophosphamide Compared to Anthracycline-Based Chemotherapy in Treating Women With HER2-Negative Breast Cancer
                                
            
            
        Unknown
                            
            
                RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of breast cancer cells, either by killing the cells or by stopping them from dividing. Giving the drugs in different combinations may kill more breast cancer cells. Giving combination chemotherapy after surgery may kill any tumor cells that remain after surgery.
PURPOSE: This randomized phase III trial is studying different combination chemotherapy regimens and their side effects and comparing how well they work in...  Read More             
        
        
    Gender:
                FEMALE
            Ages:
                18 years and above
            Trial Updated:
                04/13/2022
            
            Locations: Texas Cancer Center, Abilene, Texas  +34 locations         
        
        
            Conditions: Breast Cancer
        
            
        
    
                
                                    A Study Evaluating Safety and Efficacy of the Addition of ABT-888 Plus Carboplatin Versus the Addition of Carboplatin to Standard Chemotherapy Versus Standard Chemotherapy in Subjects With Early Stage Triple Negative Breast Cancer
                                
            
            
        Completed
                            
            
                This is a 3 arm Phase 3 study to evaluate the safety and efficacy of the addition of veliparib plus carboplatin versus the addition of carboplatin to standard neoadjuvant chemotherapy versus standard neoadjuvant chemotherapy in subjects with early stage TNBC.             
        
        
    Gender:
                FEMALE
            Ages:
                Between 18 years and 99 years
            Trial Updated:
                01/15/2021
            
            Locations: Texas Oncology - Bedford /ID# 126135, Bedford, Texas  +7 locations         
        
        
            Conditions: Triple Negative Breast Cancer
        
            
        
    
                
                                    BETH Study: Treatment of HER2 Positive Breast Cancer With Chemotherapy Plus Trastuzumab vs Chemotherapy Plus Trastuzumab Plus Bevacizumab
                                
            
            
        Terminated
                            
            
                The trial will determine the value of adding bevacizumab to chemotherapy plus trastuzumab in patients with resected node-positive or high risk node-negative, HER2-positive breast cancer.             
        
        
    Gender:
                FEMALE
            Ages:
                18 years and above
            Trial Updated:
                09/09/2020
            
            Locations: Texas Oncology- Sammons CC, Dallas, Texas  +5 locations         
        
        
            Conditions: Breast Cancer
        
            
        
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