Cyclophosphamide Clinical Trials

A collection of 2145 research studies where Cyclophosphamide is the intervention. These studies are located in the United States. Cyclophosphamide is used for conditions such as Breast Cancer, Lymphoma and Leukemia.

Home

All Treatments

Cyclophosphamide

Show Filters

Match to Clinical Trials

Access to cutting-edge treatments

Latest clinical trials

Find trials in your area

Start Matching

Filter by Age

Featured Trial

Paid Clinical Studies Nationwide

Recruiting

Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

Healthy

Healthy Volunteer Study

Learn More

* Compensation for time may be available

Featured Trial

Chronic Cough Study

Recruiting

Are you tired of living with chronic cough? The ASPIRE Study is now looking to enroll people from all backgrounds to help research potential new treatment options for chronic cough. You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you.

Conditions:

Chronic Cough

Refractory or Unexplained Chronic Cough

Cough

Asthma

Allergic Asthma

Learn More

Featured Trial

Studying an Investigational Virus Vaccine

Recruiting

The main objectives of this study are to assess the safety and effectiveness of an investigational vaccine aimed at preventing norovirus, commonly known as the stomach flu. Participants will be randomly assigned to receive either the investigational vaccine or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.

Conditions:

Healthy

Interested in vaccine studies

All Conditions

Preventative Trials

Learn More

Featured Trial

Type 2 Diabetes Clinical Trial

Recruiting

Can changing your breakfast improve your type 2 diabetes? If you have an HbA1C of 7.0% or higher, you are invited to participate in an online study at the University of Michigan.

Conditions:

Type 2 Diabetes

Diabetes Mellitus Type 2 in Obese

Diabetes Type Two

Type 2 Diabetes Mellitus

Diabete Type 2

Learn More

Study Evaluating SC262 in Subjects With r/r Non-Hodgkin's Lymphoma (VIVID)

NCT06285422

Recruiting

SC262-101 is a Phase 1 study to evaluate SC262 safety and tolerability, anti-tumor activity, cellular kinetics, immunogenicity, and exploratory biomarkers.

Gender:

ALL

Ages:

Between 18 years and 80 years

Trial Updated:

04/09/2025

Locations: The University of Kansas Hospital, Kansas City, Kansas +2 locations

Conditions: Non Hodgkin's Lymphoma, Large B-cell Lymphoma

Learn More ›

Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

NCT05327023

Recruiting

Background: People with blood cancers often receive blood or bone marrow transplants. But even with these treatments, the risk of relapse is high. Researchers want to see if giving the transplant recipient an infusion of lymphocytes (a type of white blood cell) from their transplant donor early after the transplant can reduce that risk. Objective: To learn if giving donor lymphocytes early after a transplant will help reduce the risk of relapse for people with certain blood cancers. Eligibil... Read More

Gender:

ALL

Ages:

Between 12 years and 120 years

Trial Updated:

04/09/2025

Locations: National Institutes of Health Clinical Center, Bethesda, Maryland

Conditions: Hematologic Neoplasms

Learn More ›

A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation

NCT06045806

Active Not Recruiting

The purpose of this study is to compare the efficacy, safety, and tolerability of ide-cel with lenalidomide (LEN) maintenance to that of LEN maintenance alone in adult participants with Newly Diagnosed Multiple Myeloma (NDMM) who have achieved a suboptimal response post autologous stem cell transplantation (ASCT).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/09/2025

Locations: Local Institution - 0131, Los Angeles, California +100 locations

Local Institution - 0131, Los Angeles, California

Local Institution - 0126, Orange, California

Local Institution - 0113, Sacramento, California

Colorado Blood Cancer Institute, Denver, Colorado

Yale University School of Medicine, New Haven, Connecticut

AdventHealth Orlando, Orlando, Florida

Local Institution - 0121, Atlanta, Georgia

Local Institution - 0104, Atlanta, Georgia

Local Institution - 0151, Boston, Massachusetts

Ascension Providence Hospital, Southfield, Michigan

M Health Fairview Clinics and Surgery Center, Minneapolis, Minnesota

Washington University School of Medicine, Saint Louis, Missouri

Columbia University Irving Medical Center, New York, New York

Novant Health Cancer Institute - Elizabeth, Charlotte, North Carolina

The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center, Columbus, Ohio

Local Institution - 0132, Philadelphia, Pennsylvania

Local Institution - 0124, Austin, Texas

Local Institution - 0109, Houston, Texas

University of Texas MD Anderson Cancer Center, Houston, Texas

Local Institution - 0007, Camperdown, New South Wales

Local Institution - 0005, Brisbane, Queensland

Local Institution - 0004, Melbourne, Victoria

Local Institution - 0006, Melbourne, Victoria

Local Institution - 0008, Melbourne, Victoria

Local Institution - 0011, Murdoch, Western Australia

Local Institution - 0089, Salzburg, Not set

Local Institution - 0090, Wien, Not set

Local Institution - 0083, Anderlecht, Bruxelles-Capitale, Région De

Local Institution - 0084, Brussels, Bruxelles-Capitale, Région De

Local Institution - 0144, Brussels, Bruxelles-Capitale, Région De

Local Institution - 0133, Edmonton, Alberta

Local Institution - 0001, Hamilton, Ontario

Local Institution - 0134, Montreal, Quebec

Local Institution - 0070, Odense, Syddanmark

Local Institution - 0047, Pessac, Aquitaine

Institut Paoli-Calmettes, Marseille, Bouches-du-Rhône

Hopital Claude Huriez - CHU de Lille, Lille, Nord

Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu, Nantes, Pays-de-la-Loire

Local Institution - 0046, Pierre-Bénite, Rhône

Henri Mondor Hospital, Créteil, Val-de-Marne

Local Institution - 0028, Villejuif, Val-de-Marne

Local Institution - 0029, Poitiers, Vienne

Local Institution - 0082, Paris, Not set

Institut Universitaire du Cancer Toulouse - Oncopole - CHU de TOULOUSE, Toulouse, Not set

Local Institution - 0031, Paris, Île-de-France

Local Institution - 0072, Heidelberg, Baden-Württemberg

Local Institution - 0078, Ulm, Baden-Württemberg

Local Institution - 0077, Nuremberg, Bayern

Local Institution - 0073, Köln, Nordrhein-Westfalen

Local Institution - 0087, Leipzig, Sachsen

Local Institution - 0079, Dresden, Not set

Local Institution - 0115, Essen, Not set

Local Institution - 0076, Hamburg, Not set

Local Institution - 0074, Wuerzburg, Not set

Local Institution - 0063, Patras, Achaḯa

Local Institution - 0061, Athens, Attikí

Local Institution - 0062, Chaidari, Attikí

Local Institution - 0060, Thessaloniki, Thessaloníki

Local Institution - 0055, Be'er Sheva, HaDarom

Local Institution - 0058, Petah-Tikva, HaMerkaz

Local Institution - 0057, Ramat Gan, HaMerkaz

Local Institution - 0088, Tel Aviv, Tell Abīb

Local Institution - 0056, Haifa, Not set

Local Institution - 0059, Jerusalem, Not set

Local Institution - 0064, Rozzano, Milano

Local Institution - 0065, Bologna, Not set

Local Institution - 0066, Roma, Not set

Nagoya City University Hospital, Nagoya, Aichi

Hokkaido University Hospital, Sapporo, Hokkaido

Hyogo Medical University Hospital, Nishinomiya, Hyogo

Kanazawa University Hospital, Kanazawa, Ishikawa

Local Institution - 0085, Isehara, Kanagawa

Japanese Red Cross Medical Center, Shibuya-ku, Tokyo

Chiba University Hospital, Chiba, Not set

Kyushu University Hospital, Fukuoka, Not set

Okayama University Hospital, Okayama, Not set

Local Institution - 0071, Shimotsuke, Not set

Chonnam National University Hwasun Hospital, Hwasun, Jeonranamdo

Seoul National University Hospital, Seoul, Seoul Teugbyeolsi

Local Institution - 0038, Seoul, Seoul Teugbyeolsi

Local Institution - 0043, Seoul, Seoul Teugbyeolsi

Asan Medical Center, Seoul, Seoul-teukbyeolsi

Local Institution - 0069, Oslo, Not set

Local Institution - 0027, Lublin, Lubelskie

Local Institution - 0095, Warsaw, Mazowieckie

Local Institution - 0023, Warsaw, Mazowieckie

Local Institution - 0026, Gdańsk, Not set

Local Institution - 0024, Poznań, Not set

Local Institution - 0022, Gliwice, Śląskie

Local Institution - 0091, Bucharest, Not set

Local Institution - 0020, Badalona, Barcelona [Barcelona]

Local Institution - 0017, L'Hospitalet Del Llobregat, Barcelona [Barcelona]

Hospital Clínic de Barcelona, Barcelona, Catalunya [Cataluña]

Local Institution - 0012, Pamplona, Navarra

Local Institution - 0021, Madrid, Not set

Local Institution - 0013, Salamanca, Not set

Hospital Universitari i Politecnic La Fe, València, Not set

Local Institution - 0093, Birmingham, England

Local Institution - 0080, London, London, City Of

Local Institution - 0094, London, London, City Of

Conditions: Multiple Myeloma

Learn More ›

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

NCT06717347

Recruiting

The purpose of this study is to evaluate if zilovertamab vedotin with standard treatment can help people live longer without the cancer growing or spreading than people who receive standard treatment alone.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/09/2025

Locations: Cancer Blood and Specialty Clinic ( Site 0109), Los Alamitos, California +73 locations

Cancer Blood and Specialty Clinic ( Site 0109), Los Alamitos, California

Fort Wayne Medical Oncology and Hematology ( Site 0149), Fort Wayne, Indiana

Cotton O'Neil Cancer Center ( Site 0108), Topeka, Kansas

Truman Medical Center ( Site 0122), Kansas City, Missouri

OptumCare Cancer Care ( Site 0121), Las Vegas, Nevada

Comprehensive Cancer Centers of Nevada ( Site 0113), Las Vegas, Nevada

New York Oncology Hematology, P.C. ( Site 0129), Albany, New York

University of Virginia Cancer Center ( Site 0138), Charlottesville, Virginia

Virginia Cancer Institute ( Site 0148), Richmond, Virginia

Blue Ridge Cancer Care ( Site 0132), Roanoke, Virginia

Instituto de Investigaciones Clinicas Mar del Plata ( Site 0306), Mar del Plata, Buenos Aires

Fundacion Estudios Clinicos ( Site 0311), Rosario., Santa Fe

ASBL CHU Helora - Hôpital de Mons - Site Kennedy ( Site 1103), Mons, Hainaut

CEPEN - Centro de Pesquisa e Ensino em Oncologia de Santa Catarina ( Site 0403), Florianópolis, Santa Catarina

Beijing Cancer Hospital ( Site 3101), Beijing, Beijing

Chongqing Cancer Hospital ( Site 3113), Chongqing, Chongqing

Fujian Provincial Cancer Hospital. ( Site 3119), Fuzhou, Fujian

Zhujiang Hospital of Southern Medical University ( Site 3122), Guangzhou, Guangdong

Affiliated Cancer Hospital of Guangxi Medical University ( Site 3123), Nanning, Guangxi

The Affiliated Hospital of Guizhou Medical University ( Site 3112), Guiyang, Guizhou

Affiliated Hospital of Nantong University ( Site 3117), Nantong, Jiangsu

Sichuan Cancer Hospital. ( Site 3111), Chengdu, Sichuan

Yunnan Province Cancer Hospital ( Site 3109), Kunming, Yunnan

Oncologos del Occidente ( Site 0601), Pereira., Risaralda

Aalborg University Hospital ( Site 1302), Aalborg, Nordjylland

HIA Sainte Anne ( Site 1506), Toulon, Var

Centre Hospitalier d'Avignon ( Site 1505), Avignon, Vaucluse

CELAN,S.A ( Site 0702), Guatemala., Not set

MEDI-K ( Site 0701), Guatemala, Not set

Cen Integral Onco Gastro y Hemato Onco Guatemala S.A. ( Site 0703), Guatemala, Not set

Queen Mary Hospital ( Site 3201), Hong Kong, Not set

Carmel Hospital ( Site 1903), Haifa, Not set

Hadassah Medical Center ( Site 1901), Jerusalem, Not set

Sourasky Medical Center ( Site 1904), Tel Aviv, Not set

Poria Medical Center ( Site 1902), Tiberias, Not set

Nagoya University Hospital ( Site 3309), Nagoya, Aichi

National Hospital Organization Shikoku Cancer Center ( Site 3321), Matsuyama, Ehime

Kobe City Medical Center General Hospital ( Site 3318), Kobe, Hyogo

Kanazawa University Hospital ( Site 3308), Kanazawa, Ishikawa

Tokai University Hospital ( Site 3302), Isehara, Kanagawa

Saitama Medical University Hospital ( Site 3305), Iruma-gun, Saitama

University of Yamanashi Hospital ( Site 3320), Chuo, Yamanashi

Chiba Cancer Center ( Site 3314), Chiba, Not set

Kyushu University Hospital ( Site 3313), Fukuoka, Not set

Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital ( Site 3322), Hiroshima, Not set

University Hospital,Kyoto Prefectural University of Medicine ( Site 3315), Kyoto, Not set

University of Miyazaki Hospital ( Site 3319), Miyazaki, Not set

Okayama University Hospital ( Site 3311), Okayama, Not set

Yamagata University Hospital ( Site 3312), Yamagata, Not set

National Cancer Center- Center for Hemotologic malignancy ( Site 3806), Goyang-si, Kyonggi-do

Pusan National University Hospital ( Site 3804), Busan, Pusan-Kwangyokshi

Chungnam National University Hospital ( Site 3801), Daejeon, Taejon-Kwangyokshi

Severance Hospital, Yonsei University Health System ( Site 3802), Seoul, Not set

Samsung Medical Center ( Site 3807), Seoul, Not set

Meander Medisch Centrum ( Site 2101), Amersfoort, Utrecht

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 2201), Warszawa, Mazowieckie

Pratia Onkologia Katowice ( Site 2204), Katowice, Slaskie

Szpital Kliniczny Ministerstwa Spraw Wewnętrznych i Administracji z Warmińsko-Mazurskim Centrum Onko, Olsztyn, Warminsko-mazurskie

BRCR Global - Mayaguez ( Site 1003), Mayaguez, Not set

Auxilio Mutuo Cancer Center ( Site 1001), San Juan, Not set

Institutul Oncologic Cluj ( Site 2404), Cluj-Napoca, Cluj

Hospital Universitario Virgen Macarena ( Site 2608), Sevilla, Andalucia

Hospital General Universitario Dr. Balmis ( Site 2604), Alicante, Valenciana, Comunitat

Hospital del Mar ( Site 2610), Barcelona, Not set

Hospital Universitario La Paz ( Site 2611), Madrid, Not set

Hospital Virgen de la Victoria ( Site 2609), Malaga, Not set

Ospedale Regionale Bellinzona e Valli ( Site 2701), Bellinzona, Ticino

National Cheng Kung University Hospital ( Site 3902), Tainan, Not set

MNPE ClinCenter of Oncology,Hematology,Transplantology and Palliative Care of CherkasyRegCouncil ( S, Cherkasy, Cherkaska Oblast

Communal non-profit enterprise "Regional clinical hospital of Ivano-Frankivsk Regional Council" ( Si, Ivano-Frankivsk, Ivano-Frankivska Oblast

Institute of Blood Pathology and Transfusion Medicine AMS Ukraine ( Site 2903), Lviv, Lvivska Oblast

SNPE National Cancer Institute ( Site 2902), Kyiv, Not set

Universal Clinic Oberig ( Site 2908), Kyiv, Not set

Public Non-Profit Enterprise Kyiv City Clinical Hospital #9 under the Executive Body of Kyiv City Co, Kyiv, Not set

Conditions: Diffuse Large B-Cell Lymphoma

Learn More ›

Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer

NCT06782932

Not Yet Recruiting

The purpose of this study is to determine the optimal dose of AGEN2373 that is safe when given in combination with balstilimab and Pancreatic GVAX Whole Cell Vaccine and evaluate the safety and clinical activity of balstilimab and AGEN2373 in combination with GVAX (Arm 1) or mKRASvax (Arm 2) in surgically resectable pancreatic adenocarcinoma.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/09/2025

Locations: Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland

Conditions: Pancreatic Cancer

Learn More ›

FGFR4 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory Rhabdomyosarcoma

NCT06865664

Not Yet Recruiting

Background: Rhabdomyosarcoma (RMS) is a cancer of soft tissues. It is the most common soft tissue sarcoma seen in children. RMS cancer cells have a protein called FGFR4 on their surface. Researchers want to try a new kind of treatment for RMS: They will collect a person s own T cells, a type of immune cell; then they will change the T cells so they are better able to target the FGFR4 protein and attack RMS tumor cells. The modified T cells are chimeric antigen receptor (CAR) T cells. The treatm... Read More

Gender:

ALL

Ages:

Between 3 years and 39 years

Trial Updated:

04/09/2025

Locations: National Institutes of Health Clinical Center, Bethesda, Maryland

Conditions: Rhabdomyosarcoma

Learn More ›

CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children

NCT04510051

Recruiting

This phase I trial investigates the side effects of chemotherapy and cellular immunotherapy in treating children with IL13Ralpha2 positive brain tumors that have come back after a period of improvement (recurrent) or do not respond to treatment (refractory). Cellular immunotherapy (IL13(EQ)BBzeta/CD19t+ T cells) are brain-tumor specific cells that may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as as cyclop... Read More

Gender:

ALL

Ages:

Between 4 years and 25 years

Trial Updated:

04/09/2025

Locations: City of Hope Medical Center, Duarte, California +2 locations

Conditions: Malignant Brain Neoplasm, Recurrent Malignant Brain Neoplasm, Refractory Malignant Brain Neoplasm

Learn More ›

Treatment of Relapsed or Chemotherapy Refractory Chronic Lymphocytic Leukemia or Indolent B Cell Lymphoma Using Autologous T Cells Genetically Targeted to the B Cell Specific Antigen CD19

NCT00466531

Active Not Recruiting

RATIONALE: Using T cells from the patient that have been treated in the laboratory may help the body build an effective immune response to kill cancer cells. Drugs used in chemotherapy, such as cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving laboratory-treated T cells together with cyclophosphamide may kill more cancer cells. PURPOSE: This is a two-stage protocol, consisting of a single-institutio... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/09/2025

Locations: Memorial Sloan Kettering Cancer Center, New York, New York

Conditions: Leukemia

Learn More ›

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

NCT05675410

Recruiting

This phase III trial compares the effect of adding immunotherapy (brentuximab vedotin and nivolumab) to standard treatment (chemotherapy with or without radiation) to the standard treatment alone in improving survival in patients with stage I and II classical Hodgkin lymphoma. Brentuximab vedotin is in a class of medications called antibody-drug conjugates. It is made of a monoclonal antibody called brentuximab that is linked to a cytotoxic agent called vedotin. Brentuximab attaches to CD30 positive lymphoma cells in a targeted way and delivers vedotin to kill them. A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs such as doxorubicin hydrochloride, bleomycin sulfate, vinblastine sulfate, dacarbazine, and procarbazine hydrochloride work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Cyclophosphamide is in a class of medications called alkylating agents. It works by damaging the cell's deoxyribonucleic acid (DNA) and may kill cancer cells. It may also lower the body's immune response. Etoposide is in a class of medications known as podophyllotoxin derivatives. It blocks a certain enzyme needed for cell division and DNA repair and may kill cancer cells. Vincristine is in a class of medications called vinca alkaloids. It works by stopping cancer cells from growing and dividing and may kill them. Prednisone is in a class of medications called corticosteroids. It is used to reduce inflammation and lower the body's immune response to help lessen the side effects of chemotherapy drugs. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Adding immunotherapy to the standard treatment of chemotherapy with or without radiation may increase survival and/or fewer short-term or long-term side effects in patients with classical Hodgkin lymphoma compared to the standard treatment alone. Read Less

Gender:

ALL

Ages:

Between 5 years and 60 years

Trial Updated:

04/09/2025

Locations: USA Health Strada Patient Care Center, Mobile, Alabama +333 locations

USA Health Strada Patient Care Center, Mobile, Alabama

Providence Alaska Medical Center, Anchorage, Alaska

CTCA at Western Regional Medical Center, Goodyear, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

City of Hope Corona, Corona, California

Kaiser Permanente Downey Medical Center, Downey, California

City of Hope Comprehensive Cancer Center, Duarte, California

Kaiser Permanente Dublin, Dublin, California

Kaiser Permanente-Fremont, Fremont, California

Kaiser Permanente-Fresno, Fresno, California

City of Hope Seacliff, Huntington Beach, California

UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine, California

City of Hope at Irvine Lennar, Irvine, California

City of Hope Antelope Valley, Lancaster, California

Loma Linda University Medical Center, Loma Linda, California

Miller Children's and Women's Hospital Long Beach, Long Beach, California

City of Hope at Long Beach Elm, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Cedars Sinai Medical Center, Los Angeles, California

Kaiser Permanente-Modesto, Modesto, California

City of Hope Newport Beach, Newport Beach, California

Kaiser Permanente-Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California

Kaiser Permanente Downtown Commons, Sacramento, California

Kaiser Permanente-South Sacramento, Sacramento, California

Rady Children's Hospital - San Diego, San Diego, California

Kaiser Permanente-San Francisco, San Francisco, California

Kaiser Permanente-Santa Teresa-San Jose, San Jose, California

Kaiser Permanente San Leandro, San Leandro, California

Kaiser San Rafael-Gallinas, San Rafael, California

Kaiser Permanente-Santa Rosa, Santa Rosa, California

City of Hope South Pasadena, South Pasadena, California

Kaiser Permanente-South San Francisco, South San Francisco, California

City of Hope South Bay, Torrance, California

City of Hope Upland, Upland, California

Kaiser Permanente-Vallejo, Vallejo, California

Kaiser Permanente-Walnut Creek, Walnut Creek, California

Children's Hospital Colorado, Aurora, Colorado

Smilow Cancer Hospital-Derby Care Center, Derby, Connecticut

Smilow Cancer Hospital Care Center-Fairfield, Fairfield, Connecticut

Smilow Cancer Hospital Care Center at Glastonbury, Glastonbury, Connecticut

Smilow Cancer Hospital Care Center at Greenwich, Greenwich, Connecticut

Smilow Cancer Hospital Care Center - Guilford, Guilford, Connecticut

Smilow Cancer Hospital Care Center at Saint Francis, Hartford, Connecticut

Connecticut Children's Medical Center, Hartford, Connecticut

Yale University, New Haven, Connecticut

Yale-New Haven Hospital North Haven Medical Center, North Haven, Connecticut

Smilow Cancer Hospital Care Center at Long Ridge, Stamford, Connecticut

Smilow Cancer Hospital-Torrington Care Center, Torrington, Connecticut

Smilow Cancer Hospital Care Center-Trumbull, Trumbull, Connecticut

Smilow Cancer Hospital-Waterbury Care Center, Waterbury, Connecticut

Smilow Cancer Hospital Care Center - Waterford, Waterford, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

MedStar Georgetown University Hospital, Washington, District of Columbia

Children's National Medical Center, Washington, District of Columbia

Broward Health Medical Center, Fort Lauderdale, Florida

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

University of Florida Health Science Center - Gainesville, Gainesville, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

Nicklaus Children's Hospital, Miami, Florida

AdventHealth Orlando, Orlando, Florida

Arnold Palmer Hospital for Children, Orlando, Florida

Nemours Children's Hospital, Orlando, Florida

Sacred Heart Hospital, Pensacola, Florida

Johns Hopkins All Children's Hospital, Saint Petersburg, Florida

Tampa General Hospital, Tampa, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

Saint Mary's Medical Center, West Palm Beach, Florida

Grady Health System, Atlanta, Georgia

Emory Proton Therapy Center, Atlanta, Georgia

Emory University Hospital Midtown, Atlanta, Georgia

Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia

Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia

Emory Saint Joseph's Hospital, Atlanta, Georgia

Augusta University Medical Center, Augusta, Georgia

Kapiolani Medical Center for Women and Children, Honolulu, Hawaii

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho

Saint Luke's Cancer Institute - Meridian, Meridian, Idaho

Saint Luke's Cancer Institute - Nampa, Nampa, Idaho

Saint Luke's Cancer Institute - Twin Falls, Twin Falls, Idaho

Rush - Copley Medical Center, Aurora, Illinois

Advocate Good Shepherd Hospital, Barrington, Illinois

Mount Sinai Hospital Medical Center, Chicago, Illinois

Lurie Children's Hospital-Chicago, Chicago, Illinois

Northwestern University, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Advocate Illinois Masonic Medical Center, Chicago, Illinois

AMG Crystal Lake - Oncology, Crystal Lake, Illinois

Carle at The Riverfront, Danville, Illinois

Decatur Memorial Hospital, Decatur, Illinois

Northwestern Medicine Cancer Center Kishwaukee, DeKalb, Illinois

Advocate Good Samaritan Hospital, Downers Grove, Illinois

Carle Physician Group-Effingham, Effingham, Illinois

Crossroads Cancer Center, Effingham, Illinois

Advocate Sherman Hospital, Elgin, Illinois

Elmhurst Memorial Hospital, Elmhurst, Illinois

Northwestern Medicine Cancer Center Delnor, Geneva, Illinois

Northwestern Medicine Glenview Outpatient Center, Glenview, Illinois

Northwestern Medicine Grayslake Outpatient Center, Grayslake, Illinois

Advocate South Suburban Hospital, Hazel Crest, Illinois

Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois

AMG Libertyville - Oncology, Libertyville, Illinois

Condell Memorial Hospital, Libertyville, Illinois

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois

Loyola University Medical Center, Maywood, Illinois

Edward Hospital/Cancer Center, Naperville, Illinois

HSHS Saint Elizabeth's Hospital, O'Fallon, Illinois

Advocate Christ Medical Center, Oak Lawn, Illinois

Advocate Children's Hospital-Oak Lawn, Oak Lawn, Illinois

Northwestern Medicine Orland Park, Orland Park, Illinois

Advocate Children's Hospital-Park Ridge, Park Ridge, Illinois

Advocate Lutheran General Hospital, Park Ridge, Illinois

Saint Jude Midwest Affiliate, Peoria, Illinois

Edward Hospital/Cancer Center?Plainfield, Plainfield, Illinois

UW Health Carbone Cancer Center Rockford, Rockford, Illinois

Memorial Hospital East, Shiloh, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Carle Cancer Center, Urbana, Illinois

Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois

Rush-Copley Healthcare Center, Yorkville, Illinois

Riley Hospital for Children, Indianapolis, Indiana

Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

Wesley Medical Center, Wichita, Kansas

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Norton Children's Hospital, Louisville, Kentucky

The James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky

UofL Health Medical Center Northeast, Louisville, Kentucky

Children's Hospital New Orleans, New Orleans, Louisiana

Ochsner Medical Center Jefferson, New Orleans, Louisiana

Eastern Maine Medical Center, Bangor, Maine

Maine Children's Cancer Program, Scarborough, Maine

Sinai Hospital of Baltimore, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Dana-Farber Cancer Institute, Boston, Massachusetts

UMass Memorial Medical Center - University Campus, Worcester, Massachusetts

Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan

C S Mott Children's Hospital, Ann Arbor, Michigan

Bronson Battle Creek, Battle Creek, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan

Corewell Health Dearborn Hospital, Dearborn, Michigan

Children's Hospital of Michigan, Detroit, Michigan

Henry Ford Hospital, Detroit, Michigan

Michigan State University Clinical Center, East Lansing, Michigan

Corewell Health Farmington Hills Hospital, Farmington Hills, Michigan

Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids, Michigan

Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan

Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

West Michigan Cancer Center, Kalamazoo, Michigan

Ascension Borgess Cancer Center, Kalamazoo, Michigan

Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan

Trinity Health Muskegon Hospital, Muskegon, Michigan

Cancer and Hematology Centers of Western Michigan - Norton Shores, Norton Shores, Michigan

Henry Ford Medical Center-Columbus, Novi, Michigan

Corewell Health Reed City Hospital, Reed City, Michigan

Corewell Health Children's, Royal Oak, Michigan

Corewell Health William Beaumont University Hospital, Royal Oak, Michigan

Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center, Saint Joseph, Michigan

Munson Medical Center, Traverse City, Michigan

Corewell Health Beaumont Troy Hospital, Troy, Michigan

University of Michigan Health - West, Wyoming, Michigan

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan

Mercy Hospital, Coon Rapids, Minnesota

Fairview Southdale Hospital, Edina, Minnesota

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

Abbott-Northwestern Hospital, Minneapolis, Minnesota

University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota

United Hospital, Saint Paul, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

Saint Luke's Hospital, Chesterfield, Missouri

Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri

Children's Mercy Hospitals and Clinics, Kansas City, Missouri

Cardinal Glennon Children's Medical Center, Saint Louis, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Siteman Cancer Center-South County, Saint Louis, Missouri

Siteman Cancer Center at Christian Hospital, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Siteman Cancer Center at Saint Peters Hospital, Saint Peters, Missouri

Nebraska Medicine-Bellevue, Bellevue, Nebraska

Children's Hospital and Medical Center of Omaha, Omaha, Nebraska

Nebraska Medicine-Village Pointe, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada

Renown Regional Medical Center, Reno, Nevada

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire

Cooper Hospital University Medical Center, Camden, New Jersey

Trinitas Hospital and Comprehensive Cancer Center - Williamson Street Campus, Elizabeth, New Jersey

Hackensack University Medical Center, Hackensack, New Jersey

Jersey City Medical Center, Jersey City, New Jersey

Saint Barnabas Medical Center, Livingston, New Jersey

Monmouth Medical Center, Long Branch, New Jersey

Morristown Medical Center, Morristown, New Jersey

Jersey Shore Medical Center, Neptune, New Jersey

Saint Peter's University Hospital, New Brunswick, New Jersey

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

Community Medical Center, Toms River, New Jersey

Presbyterian Hospital, Albuquerque, New Mexico

University of New Mexico Cancer Center, Albuquerque, New Mexico

Albany Medical Center, Albany, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

Roswell Park Cancer Institute, Buffalo, New York

Hematology Oncology Associates of CNY at Camillus, Camillus, New York

Hematology Oncology Associates of Central New York-East Syracuse, East Syracuse, New York

Glens Falls Hospital, Glens Falls, New York

NYU Langone Hospital - Long Island, Mineola, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

NYP/Weill Cornell Medical Center, New York, New York

University of Rochester, Rochester, New York

Stony Brook University Medical Center, Stony Brook, New York

State University of New York Upstate Medical University, Syracuse, New York

Wilmot Cancer Institute at Webster, Webster, New York

Mission Hospital, Asheville, North Carolina

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Duke University Medical Center, Durham, North Carolina

East Carolina University, Greenville, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Broadway Medical Center, Fargo, North Dakota

Children's Hospital Medical Center of Akron, Akron, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Providence Willamette Falls Medical Center, Oregon City, Oregon

Providence Portland Medical Center, Portland, Oregon

Providence Saint Vincent Medical Center, Portland, Oregon

Legacy Emanuel Children's Hospital, Portland, Oregon

Oregon Health and Science University, Portland, Oregon

Geisinger Medical Center, Danville, Pennsylvania

Penn State Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Smilow Cancer Hospital Care Center - Westerly, Westerly, Rhode Island

Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina

Medical University of South Carolina, Charleston, South Carolina

Prisma Health Richland Hospital, Columbia, South Carolina

Saint Francis Hospital, Greenville, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Saint Francis Cancer Center, Greenville, South Carolina

Prisma Health Cancer Institute - Eastside, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

T C Thompson Children's Hospital, Chattanooga, Tennessee

East Tennessee Childrens Hospital, Knoxville, Tennessee

The Children's Hospital at TriStar Centennial, Nashville, Tennessee

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Dell Children's Medical Center of Central Texas, Austin, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

El Paso Children's Hospital, El Paso, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

M D Anderson Cancer Center, Houston, Texas

Covenant Children's Hospital, Lubbock, Texas

UMC Cancer Center / UMC Health System, Lubbock, Texas

Children's Hospital of San Antonio, San Antonio, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Scott and White Memorial Hospital, Temple, Texas

Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah

Primary Children's Hospital, Salt Lake City, Utah

University of Vermont and State Agricultural College, Burlington, Vermont

University of Virginia Cancer Center, Charlottesville, Virginia

Inova Fairfax Hospital, Falls Church, Virginia

Children's Hospital of The King's Daughters, Norfolk, Virginia

Naval Medical Center - Portsmouth, Portsmouth, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Carilion Children's, Roanoke, Virginia

Valley Medical Center, Renton, Washington

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

West Virginia University Charleston Division, Charleston, West Virginia

Edwards Comprehensive Cancer Center, Huntington, West Virginia

Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin

Aurora Saint Luke's South Shore, Cudahy, Wisconsin

Aurora Health Care Germantown Health Center, Germantown, Wisconsin

Aurora Cancer Care-Grafton, Grafton, Wisconsin

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin

Aurora BayCare Medical Center, Green Bay, Wisconsin

Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin

Gundersen Lutheran Medical Center, La Crosse, Wisconsin

University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison, Wisconsin

University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin

Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Aurora Cancer Care-Milwaukee, Milwaukee, Wisconsin

Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin

Aurora Sinai Medical Center, Milwaukee, Wisconsin

ProHealth D N Greenwald Center, Mukwonago, Wisconsin

ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin

Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin

Aurora Cancer Care-Racine, Racine, Wisconsin

Saint Vincent Hospital Cancer Center at Sheboygan, Sheboygan, Wisconsin

Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin

Saint Vincent Hospital Cancer Center at Sturgeon Bay, Sturgeon Bay, Wisconsin

Aurora Medical Center in Summit, Summit, Wisconsin

Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin

UW Cancer Center at ProHealth Care, Waukesha, Wisconsin

Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin

Aurora West Allis Medical Center, West Allis, Wisconsin

University of Alberta Hospital, Edmonton, Alberta

CancerCare Manitoba, Winnipeg, Manitoba

IWK Health Centre, Halifax, Nova Scotia

Children's Hospital, London, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

Hospital for Sick Children, Toronto, Ontario

The Montreal Children's Hospital of the MUHC, Montreal, Quebec

Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec

Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke, Quebec

Jim Pattison Children's Hospital, Saskatoon, Saskatchewan

CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Quebec, Not set

University Pediatric Hospital, San Juan, Not set

Conditions: Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

Learn More ›

A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

NCT06615050

Recruiting

The purpose of this study is to assess Tacrolimus/Methotrexate/Ruxolitinib versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/09/2025

Locations: Blood and Marrow Transplant Group of Georgia, Atlanta, Georgia +2 locations

Conditions: Graft-versus-host Disease (GVHD)

Learn More ›

Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes

NCT03399773

Recruiting

This phase II trial studies how well donor umbilical cord blood transplant with ex-vivo expanded cord blood progenitor cells (dilanubicel) works in treating patients with blood cancer. Before the transplant, patients will receive chemotherapy (fludarabine, cyclophosphamide and in some cases thiotepa) and radiation therapy. Giving chemotherapy and total-body irradiation before a donor umbilical cord blood transplant helps stop the growth of cells in the bone marrow, including normal blood-forming... Read More

Gender:

ALL

Ages:

Between 10 years and 65 years

Trial Updated:

04/09/2025

Locations: Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington

Conditions: Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Hematopoietic and Lymphoid Cell Neoplasm, Myelodysplastic Syndrome, Myelodysplastic Syndrome With Excess Blasts

Learn More ›

Optimizing PTCy Dose and Timing

NCT03983850

Recruiting

Background: Stem cell or bone marrow transplants can cure or control blood cancers. Sometimes the donor cells see the recipient's body as foreign. This can cause complications. A high dose of the drug cyclophosphamide (PTCy) can help reduce these risks. Researchers want to see if a lower dose of PTCy can have the same benefits. Based on encouraging results from the first part of the study, researchers now are investigating whether a lower dose of PTCy can allow other immunosuppression to be decreased. Objective: To see if a lower dose of PTCy and now also shorter duration of another immunosuppressant called mycophenolate mofetil will help people with blood cancers have a more successful transplant and fewer side effects. Eligibility: People ages 15-65 with leukemia, lymphoma, or multiple myeloma that is not curable with standard therapy and is at high risk of returning without transplant, and their healthy adult relatives Design: Transplant participants will be screened with: Blood, urine, breathing, and heart tests Scans Chest x-ray Bone marrow samples: A needle inserted into the participant s pelvis will remove marrow and a bone fragment. Transplant recipients will stay at the hospital and be prepped with chemotherapy over 6 days for the transplant. They will get stem cells through a catheter in the chest or neck. They will get the cyclophosphamide chemotherapy. They will stay in the hospital about 4 more weeks. They will have blood transfusions. They will have frequent blood tests and 2 bone marrow samples within 1 year after the transplant. Donor participants will be screened with: Blood, urine, and heart tests Chest x-ray Scans Donor participants will have bone marrow taken from their pelvis or stem cells taken from their blood. For the blood donation, blood will be taken from a vein in one arm, move through a machine to remove white blood cells, and be returned through a vein in the other arm. Participation will last up to 5 years.... Read Less

Gender:

ALL

Ages:

Between 12 years and 120 years

Trial Updated:

04/09/2025

Locations: National Institutes of Health Clinical Center, Bethesda, Maryland

Conditions: Graft Versus Host Disease, Hematologic Neoplasms

Learn More ›