Community Care for Croup (RCT)
NCT01042145
Completed
This randomized clinical trial was to compare the effectiveness of prednisone 2mg/kg/day for 3 days vs. dexamethasone 0.6mg/kg for 1 day for treatment of children with mild or moderate croup. It was conducted in a practice-based research network of community pediatricians in the St. Louis area. Outcomes included additional health care for croup, duration of symptoms, nights of disturbed sleep, parental stress, missed work days, and adverse events. Our hypothesis was that community-based treatmen... Read More
Gender:
ALL
Ages:
Between 1 year and 8 years
Trial Updated:
09/11/2014
Locations: Washington University School of Medicine, St. Louis, Missouri
Conditions: Croup
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A Study to Assess Treatment With 2 Different Dosing Schedules of Trabectidin Administered to Patients With Advanced Cancer
NCT00060944
Completed
The purpose of this study is to test the safety and effectiveness of an investigational chemotherapy agent in patients with types of advanced cancer referred to as liposarcoma or leiomyosarcoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/28/2014
Locations: Not set, Los Angeles, California +40 locations
Conditions: Liposarcoma, Leiomyosarcoma
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Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphocytic Leukemia
NCT00003671
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating children who have newly diagnosed acute lymphocytic leukemia.
Gender:
ALL
Ages:
18 years and below
Trial Updated:
07/24/2014
Locations: Arizona Cancer Center, Tucson, Arizona +56 locations
Conditions: Leukemia
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Combination Chemotherapy in Treating Children With Very High Risk Acute Lymphocytic Leukemia
NCT00003783
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug and combining drugs in different ways may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of chemotherapy in treating children who have very high risk acute lymphocytic leukemia.
Gender:
ALL
Ages:
17 years and below
Trial Updated:
07/24/2014
Locations: Arizona Cancer Center, Tucson, Arizona +57 locations
Conditions: Leukemia
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Combination Chemotherapy, Bone Marrow Transplantation, and Radiation Therapy in Treating Infants With Acute Lymphoblastic Leukemia
NCT00002785
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. Bone marrow transplantation may allow the doctor to give higher doses of chemotherapy and kill more cancer cells. Radiation therapy uses high-energy x-rays to damage cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy, bone marrow transplantation, and radiation therapy in treatin... Read More
Gender:
ALL
Ages:
1 year and below
Trial Updated:
07/23/2014
Locations: Long Beach Memorial Medical Center, Long Beach, California +32 locations
Conditions: Leukemia
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Combination Chemotherapy in Treating Children With Stage III or Stage IV Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia
NCT00003217
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy consisting of methotrexate and cyclophosphamide in treating children who have stage III or stage IV non-Hodgkin's lymphoma or acute lymphoblastic leukemia.
Gender:
ALL
Ages:
21 years and below
Trial Updated:
07/23/2014
Locations: University of Arkansas for Medical Sciences, Little Rock, Arkansas +13 locations
Conditions: Leukemia, Lymphoma
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A Study of the Safety and Efficacy of a New Treatment for Diabetic Macular Edema
NCT00168337
Completed
This study will evaluate the safety and efficacy of an intravitreal implant of dexamethasone for the treatment of diabetic macular edema.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/10/2014
Locations: Not set, Artesia, California +13 locations
Conditions: Diabetic Macular Edema
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A Study of the Safety and Efficacy of a New Treatment for Diabetic Macular Edema
NCT00168389
Completed
This study will evaluate the safety and efficacy of an intravitreal implant of dexamethasone for the treatment of diabetic macular edema.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/10/2014
Locations: Not set, Inglewood, California +9 locations
Conditions: Diabetic Macular Edema
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Diphenhydramine, Lorazepam, and Dexamethasone in Treating Nausea and Vomiting Caused By Chemotherapy
NCT00429702
Terminated
RATIONALE: Diphenhydramine, lorazepam, and dexamethasone may help lessen or prevent nausea and vomiting in patients treated with chemotherapy. It is not yet known whether diphenhydramine, lorazepam, and dexamethasone are more effective than standard therapy in treating nausea and vomiting caused by chemotherapy. PURPOSE: This randomized phase II trial is studying diphenhydramine, lorazepam, and dexamethasone to see how well they work compared with standard therapy in treating nausea and vomitin... Read More
Gender:
ALL
Ages:
Between 8 years and 18 years
Trial Updated:
06/26/2014
Locations: Children's Hospital of Southwest Florida, Fort Myers, Florida +6 locations
Conditions: Nausea, Vomiting, Unspecified Childhood Solid Tumor, Protocol Specific
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An Efficacy and Safety Study for Yondelis (Trabectedin) in Patients With Advanced Relapsed Ovarian Cancer
NCT00113607
Completed
The purpose of the study is to compare the progression-free survival (PFS) of the combination of trabectedin + DOXIL with DOXIL monotherapy in patients with ovarian cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
06/18/2014
Locations: Not set, Mobile, Alabama +112 locations
Conditions: Ovarian Cancer
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The Effects of Dexamethasone on the Duration of Sciatic Nerve Blocks
NCT00616603
Terminated
Dexamethasone is a commonly used steroid. This medication has been used for many years by physicians for many different indications. Recent articles, multiple case reports, and experience at this institution have indicated that dexamethasone successfully prolongs the effective duration of local anesthetics for regional blocks. This can cause a significant reduction in postoperative pain and the decreased need for postoperative narcotics. Although other adjuncts can be used for prolonging nerve b... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
06/10/2014
Locations: Loma Linda University Medical Center, Loma Linda, California
Conditions: Total Knee Arthroplasty
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Papillary Serous Carcinoma of the Endometrium
NCT00515073
Completed
Primary Objectives: * To evaluate the results of Paclitaxel and pelvic radiation in pelvic confined papillary serous carcinoma of the endometrium for both local control and overall survival. * To evaluate the toxicity of Paclitaxel and pelvic radiation. * To collect and evaluate patients' quality of life/symptom assessment data.
Gender:
FEMALE
Ages:
All
Trial Updated:
05/30/2014
Locations: M. D. Anderson Cancer Center - Orlando, Orlando, Florida +1 locations
Conditions: Endometrial Cancer
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