A Phase II Study of Moxidex Ophthalmic Solution for Treatment of Marginal Corneal Infiltrates
NCT00579020
Terminated
The purpose of the study is to determine whether Moxidex ophthalmic solution is safe and effective in treating marginal corneal infiltrates.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
12/03/2012
Locations: Contact Alcon Call Center at 1-888-451-3937, Fort Worth, Texas
Conditions: Corneal Infiltrates
Register for Updates
Treatment of Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplasia
NCT00136084
Completed
The purpose of this study is to compare the effectiveness of two multi-agent chemotherapy regimens using different dosages of cytarabine to eliminate all detectable leukemia.
Gender:
ALL
Ages:
21 years and below
Trial Updated:
11/02/2012
Locations: Stanford University Medical Center, Palo Alto, California +7 locations
Conditions: Leukemia, Myelocytic, Acute
Register for Updates
Phase II Trial of Sequential Chemotherapy and Radiotherapy for AIDS-Related Primary Central Nervous System Lymphoma
NCT00000801
Completed
To estimate the response rate, overall and disease-free survival, toxicities, factors associated with outcome, and effect on quality of life in patients with AIDS-related primary CNS lymphoma treated with CHOD (cyclophosphamide, doxorubicin, vincristine, and dexamethasone) plus filgrastim (granulocyte-colony stimulating factor; G-CSF) and external beam irradiation. To determine other clinical markers present in this patient population. Combined modality therapy may prove of benefit for patients... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
10/31/2012
Locations: San Francisco AIDS Clinic / San Francisco Gen Hosp, San Francisco, California +6 locations
Conditions: Lymphoma, Non-Hodgkin, HIV Infections
Register for Updates
Ozurdex for Combined Pseudophakic Cystoid Macular Edema and Diabetic Macular Edema After Cataract Surgery
NCT01284478
Completed
The purpose of the study is to determine where a sustained steroid delivery system (Ozurdex,Allergan) is safe and effective to treat Cystoid Macular Edema in diabetic patients after Cataract Surgery
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/03/2012
Locations: Northern California Retina Vitreous Associates, Mountain View, California
Conditions: Pseudophakic Cystoid Macular Edema,, Diabetic Macular Edema
Register for Updates
Intravenous And Oral Casopitant (GW679769) For The Prevention Of Chemotherapy Induced Nausea And Vomiting
NCT00366834
Completed
This is a Phase III trial designed to demonstrate that casopitant (GW679769) plus dexamethasone and ondansetron is more effective in the prevention of vomiting than dexamethasone and ondansetron alone following the administration of moderately emetogenic chemotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/06/2012
Locations: GSK Investigational Site, Birmingham, Alabama +222 locations
Conditions: Vomiting, Nausea, Nausea and Vomiting, Chemotherapy-Induced
Register for Updates
Safety and Efficacy of Dexamethasone as Adjunctive Therapy to Ranibizumab in Subjects With Choroidal Neovascularization and Age-Related Macular Degeneration
NCT01122511
Terminated
This study will evaluate the safety and efficacy of dexamethasone (OZURDEX®) as adjunctive therapy to ranibizumab (LUCENTIS®) compared with ranibizumab alone in the treatment of patients with choroidal neovascularization secondary to age-related macular degeneration
Gender:
ALL
Ages:
50 years and above
Trial Updated:
08/01/2012
Locations: Not set, Fort Myers, Florida +1 locations
Conditions: Subfoveal Choroidal Neovascularization, Age-Related Maculopathy
Register for Updates
Safety and Efficacy of a New Therapy as Adjunctive Therapy to Anti-vascular Endothelial Growth Factor (Anti-VEGF) in Subjects With Wet Age-Related Macular Degeneration (AMD)
NCT00775411
Completed
The study will evaluate the safety and efficacy of the intravitreal dexamethasone implant as adjunctive therapy to Anti-VEGF treatment in the study eye of treatment naïve subjects with choroidal neovascularization secondary to age-related macular degeneration. Subjects will be followed for 26 weeks.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
08/01/2012
Locations: Not set, San Antonio, Texas +2 locations
Conditions: Choroidal Neovascularization, Age-Related Maculopathy
Register for Updates
Study of the Effects of Ciclesonide Hydrofluoroalkane (HFA) Nasal Aerosol on Hypothalamic-Pituitary-Adrenal (HPA) Axis
NCT01033825
Completed
To demonstrate the effects of ciclesonide applied as a nasal aerosol and ciclesonide aqueous (AQ) nasal spray on hypothalamic-pituitary-adrenal axis.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
07/17/2012
Locations: Clinical Research Atlanta, Stockbridge, Georgia +5 locations
Conditions: Perennial Allergic Rhinitis
Register for Updates
Phase I Study of Perifosine + Lenalidomide and Dexamethasone for Patients With Multiple Myeloma
NCT00415064
Completed
This is a phase I study of perifosine in combination with lenalidomide and dexamethasone for patients with relapsed or refractory multiple myeloma. The current protocol will enroll patients with relapsed or refractory multiple myeloma requiring second or third line therapy. Six patients each will be treated with at one of 4 dose levels in a phase 1 study. All patients will receive perifosine, lenalidomide and dexamethasone of each 28 day cycle. The doses of perifosine and lenalidomide will be va... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/03/2012
Locations: Not set, Ann Arbor, Michigan
Conditions: Multiple Myeloma
Register for Updates
A Study to Evaluate the Clinical Efficacy and Safety of Tobradex® ST Compared to Azasite® in the Treatment of Subjects With Moderate to Severe Chronic Blepharitis
NCT01102244
Completed
The purpose of this study is to evaluate the clinical efficacy and safety of Tobradex ST compared to AzaSite in the treatment of moderate to severe chronic blepharitis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/07/2012
Locations: Ora, Andover, Massachusetts
Conditions: Blepharitis
Register for Updates
Arsenic Trioxide, Thalidomide, Dexamethasone, and Ascorbic Acid in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT00227682
Terminated
RATIONALE: Drugs used in chemotherapy, such as arsenic trioxide, dexamethasone, and ascorbic acid, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. Sometimes when chemotherapy is given, it does not stop the growth of cancer cells. The cancer is said to be resistant to chemotherapy. Giving arsenic trioxide together with chemotherapy may reduce d... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/24/2012
Locations: OHSU Knight Cancer Institute, Portland, Oregon
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Register for Updates
Corticosteroid Injection for Common Upper Extremity Problems
NCT00438672
Completed
The purpose of the study is to compare the effectiveness of a steroid injection to a placebo (inactive substance) in the treatment of lateral elbow pain, deQuervain's tendonitis, or base of the thumb carpometacarpal (CMC) arthritis. We are also trying to identify which personality factors and mindsets influence perceptions of elbow, wrist and hand pain. We hope to enroll 213 subjects in this study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/25/2012
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Lateral Elbow Pain
Register for Updates