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Dexamethasone Treatment Options
A collection of 1461 research studies where Dexamethasone is the interventional treatment. These studies are located in the United States . Dexamethasone is used for conditions such as Multiple Myeloma, Postoperative Pain and Lymphoma.
481 - 492 of 1461
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Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.
Recruiting
This will be a placebo controlled, randomized, double-blind, comparative effectiveness study, in which we patients are enrolled during an emergency department (ED) visit for acute radicular low back pain (LBP) and followed by telephone two and seven days later. Patients will be randomized to receive an oral dose of dexamethasone for 2 consecutive days or placebo during an ED visit for acute radicular LBP. Every patient will receive a 7 day supply of ibuprofen and a low back pain education sessio... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
05/14/2024
Locations: Albert Einstein College of Medicine/Montefiore Medical Center - Weiler ED, Bronx, New York +1 locations
Conditions: Radiculopathy, Lumbosacral Region, Back Pain With Radiation, Low Back Pain
Ixazomib (MLN9708) and Dexamethasone in High Risk Smoldering Multiple Myeloma: A Clinical and Correlative Pilot Study
Completed
The purpose of this study is to see what effects, good and/or bad, the combination of ixazomib and dexamethasone has on the patient and the smoldering multiple myeloma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: Memorial Sloan Kettering Cancer Center, Basking Ridge, New Jersey +5 locations
Conditions: Multiple Myeloma, High Risk Smoldering Multiple Myeloma
Dexamethasone vs Ondansetron After Cesarean Delivery
Completed
The goal of this clinical trial is to compare medications in women having a cesarean delivery. The main question it aims to answer are:
• Which medication is better to use as a first-line prevention agent for nausea and vomiting Participants will rate their nausea, pain and other symptoms after surgery Researchers will compare two drugs, ondansetron and dexamethasone to see if the side effects of pain medications are improved after cesarean.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
05/06/2024
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Nausea and Vomiting, Postoperative, Cesarean Section Complications
Perioperative Glucocorticoid Administration in the Treatment of Adult Distal Radius Fractures
Recruiting
The purpose of this investigation is to compare functional outcome measures and range of motion for patients receiving glucocorticoid (GC) injections versus those not receiving GCs for the treatment of distal radius fractures. The investigators hypothesize that patients who receive GC will have improved ROM and functional outcome measures compared to patients who do not receive GC. In addition, this study aims to determine if there is a difference in rates of complications and postoperative pain... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: Geisinger Woodbine, Danville, Pennsylvania
Conditions: Distal Radius Fracture
Multi-center, Open-label, Phase 1b Study in Patients With Relapsed/Refractory Multiple Myeloma (RRMM)
Completed
Primary Objectives:
* To evaluate the safety and tolerability of isatuximab administered subcutaneously (SC) versus intravenously (IV)
* To assess the safety and tolerability (including local injection site tolerability) of isatuximab using the (investigational) isatuximab injector device
* To evaluate the pharmacokinetics (PK) of SC and IV isatuximab
Secondary Objectives:
* To estimate absolute bioavailability of SC and IV isatuximab
* To measure receptor occupancy (RO) after isatuximab SC v... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/26/2024
Locations: ~Banner MD Anderson Cancer Center Site Number : 8400005, Gilbert, Arizona +13 locations
Conditions: Multiple Myeloma
Isatuximab in Combination With Chemotherapy in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia
Terminated
Primary Objective:
Evaluate the anti-leukemic activity of isatuximab in combination with standard chemotherapies in pediatric participants of ages 28 days to less than 18 years with Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Acute Myeloid Leukemia (AML)
Secondary Objectives:
* Safety and tolerability assessments
* Assessment of infusion reactions (IRs)
* Pharmacokinetics (PK) of isatuximab
* Minimal residual disease
* Overall response rate
* Overall survival
* Event free surviv... Read More
Gender:
ALL
Ages:
Between 28 days and 17 years
Trial Updated:
04/22/2024
Locations: Sarah Cannon Research Institute-Site Number:8400001, Nashville, Tennessee +40 locations
Conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Hormonal Mechanisms of Sleep Restriction - Axis Study
Active Not Recruiting
The purpose of this study is to 1) determine how hypothalamic-pituitary-adrenal axis (HPA axis) activation occurs with sleep restriction 2) evaluate how hypothalamic-pituitary-gonadal axis (HPG axis) deactivation occurs with sleep restriction. The investigator will also examine the cognitive function associated with sleep restriction, including food intake and food cravings.
Gender:
MALE
Ages:
Between 22 years and 45 years
Trial Updated:
04/22/2024
Locations: Los Angeles Biomedical Research Institute, Torrance, California
Conditions: Sleep Restriction
Study of Dexamethasone Plus IXAZOMIB (MLN9708) or Physicians Choice of Treatment in Relapsed or Refractory Systemic Light Chain (AL) Amyloidosis
Terminated
The purpose of this study is to provide continued access of ixazomib and/or other study medications and to continue collecting relevant safety data to monitor participant's safety, determine whether dexamethasone plus IXAZOMIB improves hematologic response, 2-year vital organ (that is, heart or kidney) deterioration and mortality rate versus a physician's choice of a chemotherapy regimen in participants diagnosed with relapsed or refractory systemic light chain (AL) amyloidosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/19/2024
Locations: Cedars Sinai Medical Center, Los Angeles, California +65 locations
Conditions: Relapsed or Refractory Systemic Light Chain Amyloidosis
Steroids After Spine Fusion Surgery
Not Yet Recruiting
This trial studies how well low-dose postoperative corticosteroids (FDA approved) affect patient outcomes (patient reported outcomes, pain medication use, length of stay, major complications, and time to first bowel movement) after thoracic and/or lumbar spine fusion surgery.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
04/18/2024
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Spine Fusion
Sotatercept (ACE-011) With Lenalidomide or Pomalidomide and Dexamethasone in Relapsed/Refractory Multiple Myeloma
Active Not Recruiting
It is possible that the combination of lenalidomide, dexamethasone and ACE 011 may reduce or prevent the growth of cancer cells along with improving anemia and bone lesions that sometimes occur in people with multiple myeloma.
This current study is the first study combining ACE 011 with lenalidomide. In this research study, the investigators are looking for the highest dose of ACE 011 that can be given with lenalidomide and dexamethasone. The investigators will also begin to collect information... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: Emory University, Atlanta, Georgia +3 locations
Conditions: Multiple Myeloma
A Study in Adults With Untreated Acute Lymphoblastic Leukemia
Active Not Recruiting
The purpose of this study is to determine the safety and optimal dosing of L-asparaginase in adult patients with acute lymphoblastic leukemia (ALL) between the ages of 18 and 50 years.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
04/16/2024
Locations: Dana-Farber Cancer Institute, Boston, Massachusetts +11 locations
Conditions: Acute Lymphoblastic Leukemia
Study of Venetoclax in Combination With Carfilzomib and Dexamethasone in Participants With Relapsed or Refractory Multiple Myeloma (MM)
Active Not Recruiting
A Phase 2, open-label, dose escalation study to evaluate the safety and efficacy of venetoclax in combination with carfilzomib-dexamethasone (Kd) in participants with relapsed or refractory MM and have received 1 to 3 prior lines of therapy.
Part 4 of this study is currently enrolling.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/15/2024
Locations: University of Alabama at Birmingham - Main /ID# 151405, Birmingham, Alabama +31 locations
Conditions: Multiple Myeloma
481 - 492 of 1461