Dexamethasone Treatment Options

A collection of 1455 research studies where Dexamethasone is the interventional treatment. These studies are located in the United States. Dexamethasone is used for conditions such as Multiple Myeloma, Lymphoma and Postoperative Pain.

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Featured Trial

Paid Clinical Studies Nationwide

Recruiting

Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

Healthy

Healthy Volunteer Study

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* Compensation for time may be available

Featured Trial

Chronic Cough Research Study

Recruiting

Are you tired of living with chronic cough? Our research study is now looking to enroll people from all backgrounds to help research potential new treatment options for chronic cough.
You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you!

Conditions:

Chronic Cough

Refractory or Unexplained Chronic Cough

Cough

Asthma

Sinusitis

Learn More

Featured Offer

Lose Weight with GLP-1 Medications

Recruiting

Policy Lab has partnered with CareGLP to offer trusted access to GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.

GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.

As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.

Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

Learn More

BrECADD Therapy in Stage 2 B-IV Hodgkin Lymphoma

NCT07002216

Not Yet Recruiting

The purpose of this study is to further assess the efficacy and tolerability of a regimen of Brentuximab Vedotin, Etoposide, Cyclophosphamide, Doxorubicin, Dacarbazine, and Dexamethasone (BrECADD) in patients with Stage 2 B-IV Hodgkin Lymphoma (HL) with an exploratory objective to assess the clinical utility of Circulating tumor DNA (ctDNA) as a biomarker for minimal residual disease (MRD) and depth of treatment response.

Gender:

ALL

Ages:

Between 18 years and 60 years

Trial Updated:

05/23/2025

Locations: University of Miami, Miami, Florida

Conditions: Hodgkin Lymphoma, Advanced Hodgkin Lymphoma

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A Study of Daratumumab

NCT05438043

Recruiting

The purpose of this study is to provide ongoing access to study treatments for participants with multiple myeloma or smoldering multiple myeloma benefiting from treatment in certain Janssen Research and Development (R\&D) studies that use daratumumab as part of the study treatment regimen: access for all participants regardless of treatment group in daratumumab studies and access to participants in daratumumab-containing arms in the non-daratumumab studies will be allowed from studies which have... Read More

Gender:

ALL

Ages:

All

Trial Updated:

05/22/2025

Locations: University of Miami Sylvester Cancer Center, Miami, Florida +75 locations

University of Miami Sylvester Cancer Center, Miami, Florida

Emory University, Atlanta, Georgia

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

Barnes-jewish Hospital, Saint Louis, Missouri

Icahn School of Medicine at Mount Sinai - The Derald H. Ruttenberg, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

Baylor University Medical Center, Dallas, Texas

ZNA Stuivenberg, Antwerpen, Not set

Peking Union Medical College Hospital, Beijing, Not set

Beijing Chaoyang Hospital, Beijing, Not set

Peking University First Hospital, Beijing, Not set

Peking University People s Hospital, Beijing, Not set

The First Bethune Hospital of Jilin University, Changchun, Not set

West China Hospital Si Chuan University, Chengdu, Not set

Fujian Medical University, Fuzhou, Not set

Guangdong General Hospital, Guangzhou, Not set

Nanfang Hospital, Guangzhou, Not set

First Affiliated Hospital Medical School of Zhejiang University, Hangzhou, Not set

First affiliated Hospital of Zhejiang University, Hangzhou, Not set

Shanghai Changzheng Hospital, Shanghai, Not set

Ruijin Hospital Shanghai Jiao Tong University, Shanghai, Not set

Renji Hospital, Shanghai Jiaotong University School of Medicine, ShangHai, Not set

First Affiliated Hospital SooChow University, Suzhou, Not set

Tianjin cancer hospital, Tianjin, Not set

Institute of Hematology and Blood Diseases Hospital, Tianjin, Not set

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Not set

Henan Cancer Hospital, Zhengzhou, Not set

Aarhus University Hospital, Aarhus N, Not set

Centre Hospitalier Universitaire (CHU) de Caen, Caen, Not set

CHU Nantes, Nantes Cedex 1, Not set

Hopital Saint Louis, Paris, Not set

Hopital Haut Leveque, Pessac, Not set

Klinikum Chemnitz gGmbH, Chemnitz, Not set

Asklepios Klinik Altona, Hamburg, Not set

Universitaetsklinikum Tuebingen der Eberhard-Karls-Universitaet, Abteilung fuer Innere Medizin II,, Tübingen, Not set

Alexandra General Hospital of Athens, Athens Attica, Not set

Anticancer Hospital of Thessaloniki Theageneio, Thessaloniki, Not set

Universita Degli Studi di Roma Tor Vergata, Roma, Not set

Sapienza University of Rome, Roma, Not set

Pusan National University Hospital, Busan, Not set

National Cancer Center, Goyang si, Not set

Chonnam National University Hwasun Hospital, Hwasun, Not set

Seoul National University Bundang Hospital, Seongnam, Not set

Seoul National University Hospital, Seoul, Not set

Samsung Medical Center, Seoul, Not set

The Catholic University of Korea Seoul St Marys Hospital, Seoul, Not set

Wojewodzki Szpital Specjalistyczny w Legnicy, Legnica, Not set

Uniwersytecki Szpital Kliniczny w Poznaniu, Poznan, Not set

S.P. Botkin Moscow City Clinical Hospital, Moscow, Not set

Nizhniy Novgorod Region Clinical Hospital, Nizhny Novgorod, Not set

Republican Hospital named by V.A.Baranova, Petrozavodsk, Not set

Ryazan Regional Clinical Hospital, Ryazan, Not set

City Hospital No.15, Saint-Petersburg, Not set

Saratov State Medical University, Saratov, Not set

Clinical Research Institute of Hematology and Transfusiology, St-Petersburg, Not set

Oncology Dispensary of Komi Republic, Syktyvkar, Not set

Hosp. Univ. Germans Trias I Pujol, Badalona, Not set

Hosp Clinic de Barcelona, Barcelona, Not set

Inst. Cat. Doncologia-H Duran I Reynals, Hospitalet de Llobregat, Not set

Hosp. Univ. de Canarias, La Laguna, Not set

Hosp. Gral. Univ. Gregorio Maranon, Madrid, Not set

Clinica Univ. de Navarra, Madrid, Not set

Hosp. Univ. Ramon Y Cajal, Madrid, Not set

Hosp. Univ. 12 de Octubre, Madrid, Not set

Centro Integral Oncológico Clara Campal, Madrid, Not set

Hosp. Gral. Univ. J.M. Morales Meseguer, Murcia, Not set

Clinica Univ. de Navarra, Pamplona, Not set

Hosp Clinico Univ de Salamanca, Salamanca, Not set

Hosp. Univ. Dr. Peset, Valencia, Not set

Ege Universitesi Tip Fakultesi, Izmir, Not set

Communal Nonprofit Enterprise 'Cherkasy Regional Oncology Dispensary Of Cherkasy Regional Council', Cherkasy, Not set

Dnepropetrovsk City Clinical Hospital #4, Regional Hematology Center, Dnepropetrovsk, Not set

Kharkov Regional Clinical Oncology Center, Dept. of Hematology, Kharkov, Not set

Vinnytsya Regional Clinical Hospital named after M.I.Pirogov, Vinnitsa, Not set

St James University Hospital, Leeds, Not set

Royal Marsden Hospital, Surrey, Not set

Conditions: Multiple Myeloma

Learn More ›

A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma

NCT04133636

Recruiting

The purpose of this study is to evaluate the overall minimal residual disease (MRD) negative rate of participants who receive JNJ-68284528.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/22/2025

Locations: University Of California San Diego, San Diego, California +46 locations

University Of California San Diego, San Diego, California

University of California San Francisco, San Francisco, California

Yale University School Of Medicine, New Haven, Connecticut

Moffitt Cancer Center, Tampa, Florida

Emory University, Atlanta, Georgia

Northwestern University, Chicago, Illinois

University of Chicago, Chicago, Illinois

Indiana University, Indianapolis, Indiana

University of Iowa Hospitals and Clinics, Iowa City, Iowa

University of Kansas Cancer Center, Westwood, Kansas

Norton Cancer Institute, Louisville, Kentucky

Dana Farber Cancer Institute, Boston, Massachusetts

Barbara Ann Karmanos Cancer Institute, Detroit, Michigan

Mayo Clinic Rochester, Rochester, Minnesota

Washington University School Of Medicine, Saint Louis, Missouri

Hackensack University Medical Center, Hackensack, New Jersey

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

Montefiore Medical Center, Bronx, New York

Roswell Park Cancer Institute, Buffalo, New York

Mount Sinai Medical Center, New York, New York

Memorial Sloan-Kettering Cancer Center, New York, New York

Levine Cancer Institute, Carolinas HealthCare System, Charlotte, North Carolina

Cleveland Clinic, Cleveland, Ohio

Oregon Health And Science University, Portland, Oregon

University of Pennsylvania, Philadelphia, Pennsylvania

Thomas Jefferson University, Philadelphia, Pennsylvania

University of Pittsburgh, Pittsburgh, Pennsylvania

University of Texas Southwestern Medical Center, Dallas, Texas

University of Utah, Salt Lake City, Utah

University of Virginia, Charlottesville, Virginia

Virginia Commonwealth University - Massey Cancer Center, Richmond, Virginia

Fred Hutchinson Cancer Center, Seattle, Washington

University of Wisconsin Carbone Cancer Center, Madison, Wisconsin

UZ Gent, Gent, Not set

UZ Leuven, Leuven, Not set

CHRU de Lille Hopital Claude Huriez, Lille, Not set

C.H.U. Hotel Dieu - France, Nantes, Not set

Hopital Saint Louis, Paris cedex 10, Not set

Universitaetsklinikum Hamburg Eppendorf, Hamburg, Not set

Universitatsklinikum Wurzburg, Wuerzburg, Not set

Sheba Medical Center Tel Hashomer, Ramat Gan, Not set

Tel Aviv Sourasky Medical Center, Tel-Aviv, Not set

VU Medisch Centrum, Amsterdam, Not set

University Medical Center Groningen, Groningen, Not set

King Faisal Specialist Hospital & Research Center, Riyadh, Not set

Clinica Univ. de Navarra, Pamplona, Not set

Hosp Clinico Univ de Salamanca, Salamanca, Not set

Conditions: Multiple Myeloma

Learn More ›

A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma

NCT05083169

Active Not Recruiting

The purpose of this study is to compare the efficacy of teclistamab daratumumab (Tec-Dara) with daratumumab subcutaneously (SC) in combination with pomalidomide and dexamethasone (DPd) or daratumumab SC in combination with bortezomib and dexamethasone (DVd).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/22/2025

Locations: University of Alabama Birmingham, Birmingham, Alabama +173 locations

University of Alabama Birmingham, Birmingham, Alabama

City of Hope, Duarte, California

Stanford University Medical Center, Stanford, California

Yale University, New Haven, Connecticut

Emory University Winship Cancer Institute, Atlanta, Georgia

Tufts Medical Center, Boston, Massachusetts

Henry Ford Hospital, Detroit, Michigan

Ascension Providence Hospital, Southfield, Michigan

Cleveland Clinic, Cleveland, Ohio

West Penn Hospital, Pittsburgh, Pennsylvania

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania

Medical University of South Carolina, Charleston, South Carolina

Baptist Cancer Center, Memphis, Tennessee

Vanderbilt Ingram Cancer Center, Nashville, Tennessee

University of Texas Southwestern Medical Center, Dallas, Texas

Huntsman Cancer Institute, Salt Lake City, Utah

Fred Hutchinson Cancer Center, Seattle, Washington

University of Wisconsin Carbone Cancer Center, Madison, Wisconsin

Hospital Aleman, Buenos Aires, Not set

Hospital Italiano de Buenos Aires, Buenos Aires, Not set

Hospital Privado Centro Medico de Cordoba, Cordoba, Not set

ZNA Cadix, Antwerpen, Not set

AZ St.-Jan Brugge-Oostende AV, Brugge, Not set

UZ Gent, Gent, Not set

Hopital de Jolimont, Haine Saint Paul La Louviere, Not set

Az Groeninge, Kortrijk, Not set

UZ Leuven, Leuven, Not set

Algemeen Ziekenhuis Delta, Roeselare, Not set

Hospitais Integradaos da Gavea S/A - DF Star, Brasilia, Not set

Liga Paranaense de Combate ao Cancer, Curitiba, Not set

Centro de Pesquisa e Ensino em Oncologia de Santa Catarina CEPEN, Florianopolis, Not set

Liga Norte Riograndense Contra O Cancer, Natal, Not set

Irmandade Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Not set

Instituto de Educacao, Pesquisa e Gestao em Saude Instituto Americas (COI), Rio de Janeiro, Not set

Hospital Sao Rafael, Salvador, Not set

Real e Benemerita Associacao Portuguesa de Beneficencia, Sao Paulo, Not set

Hospital Paulistano, Sao Paulo, Not set

Clinica Medica Sao Germano S/S LTDA, Sao Paulo, Not set

Instituto D Or de Pesquisa e Ensino IDOR, São Paulo, Not set

Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta

Cross Cancer Institute, Edmonton, Alberta

BC Cancer Agency - Vancouver BC, Vancouver, British Columbia

QEII Health Sciences, Halifax, Nova Scotia

Princess Margaret Cancer Centre University Health Network, Toronto, Ontario

Peking University First Hospital, Beijing, Not set

Peking University People s Hospital, Beijing, Not set

Peking University Third Hospital, Beijing, Not set

The First Hospital of Jilin University, Changchun, Not set

The Third Xiangya Hospital of Central Sourth University, Changshashi, Not set

Beijing Chaoyang Hospital, Chaoyang District, Not set

West China Hospital Sichuan University, Chengdu, Not set

Fujian Meidical University Union Hospital, Fuzhou, Not set

Sun Yat Sen University Cancer Center, Guangzhou, Not set

First affiliated Hospital of Zhejiang University, Hangzhou, Not set

Zhongda Hospital Southeast University, Nanjing, Not set

First Affiliated Hospital of Guangxi Medical University, Nanning, Not set

Shanghai Zhongshan Hospital, Shanghai, Not set

Shengjing Hospital Of China Medical University, Shenyang, Not set

Peking University Shenzhen Hospital, Shenzhen, Not set

Tianjin Medical University General Hospital, Tianjin, Not set

Tianjin Medical University Cancer Institute and Hospital, Tianjin, Not set

The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Not set

The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Not set

Henan Cancer Hospital, Zhengzhou, Not set

Aalborg University Hospital, Aalborg, Not set

Aarhus University Hospital, Aarhus N, Not set

Rigshospitalet, Copenhagen, Not set

Odense Universitets Hospital, Odense, Not set

Vejle Hospital, Vejle, Not set

CHU Henri Mondor, Creteil, Not set

CHRU de Lille Hopital Claude Huriez, LILLE Cedex, Not set

CHU de Limoges Hopital Dupuytren, Limoges, Not set

C.H.U. Hotel Dieu - France, Nantes, Not set

Centre hospitalier Lyon-Sud, Pierre Benite cedex, Not set

CHU De Poitiers, Poitiers, Not set

Institut de Cancerologie Strasbourg Europe ICANS, Strasbourg, Not set

Pôle IUC Oncopole CHU, Toulouse cedex 9, Not set

CHRU Hôpital Bretonneau, Tours, Not set

Universitätsklinikum Carl-Gustav-Carus Dresden, Dresden, Not set

Heinrich-Heine -Universitaet Duesseldorf, Düsseldorf, Not set

Evang. Krankenhaus Essen-Mitte gGmbH, Essen, Not set

Universitatsklinikum Freiburg, Freiburg, Not set

Universitaetsklinikum Hamburg Eppendorf, Hamburg, Not set

St. Barbara-Klinik Hamm GmbH, Hamm, Not set

Universitaetsklinikum Heidelberg, Heidelberg, Not set

Universitaetsklinikum Schleswig Holstein Campus Kiel, Kiel, Not set

Universitaetsklinikum Leipzig, Leipzig, Not set

Universitaetsklinikum Tuebingen, Tubingen, Not set

Alexandra General Hospital of Athens, Athens Attica, Not set

Anticancer Hospital of Thessaloniki Theageneio, Thessaloniki, Not set

G.Papanikolaou, Thessaloniki, Not set

U.O. Ematologia con Trapianto- AOU Policlinico di Bari, Bari, Not set

ASST Papa Giovanni XXIII Bergamo, Bergamo, Not set

Policlinico Sant'Orsola Malpighi, Bologna, Not set

Azienda Ospedaliera Universitaria Careggi, Firenze, Not set

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, Not set

IRCCS Policlinico San Matteo, Università degli studi di Pavi, Pavia, Not set

Università di Roma 'La Sapienza' - Ospedale Umberto 1°, Roma, Not set

A.O.U. Citta della Salute e della Scienza di Torino - Presidio Molinette, Turin, Not set

Fukuoka University Hospital, Fukuoka, Not set

Ogaki Municipal Hospital, Gifu, Not set

National Hospital Organization Mito Medical Center, Higashiibaraki-gun, Not set

Tokai University Hospital, Isehara, Not set

Shonan Kamakura General Hospital, Kamakura-shi, Not set

National Cancer Center Hospital East, Kashiwa, Not set

Dokkyo Medical University Saitama Medical Center, Koshigaya, Not set

Kumamoto University Hospital, Kumamoto, Not set

Kurume University Hospital, Kurume, Not set

National Hospital Organization Matsumoto Medical Center, Matsumoto, Not set

Nagoya City University Hospital, Nagoya, Not set

Hyogo Medical University Hospital, Nishinomiya shi, Not set

National Hospital Organization Okayama Medical Center, Okayama, Not set

National Hospital Organization Hiroshima-Nishi Medical Center, Otake, Not set

Hokkaido University Hospital, Sapporo-shi, Not set

National Hospital Organization Sendai Medical Center, Sendai-City, Not set

Tohoku University Hospital, Sendai, Not set

Japanese Red Cross Medical Center, Shibuya-ku, Not set

Iwate Medical University Hospital, Shiwa-gun, Not set

Kyungpook National University Hospital, Daegu, Not set

Gachon University Gil Medical Center, Incheon, Not set

Chonnam National University Hwasun Hospital, Jeollanam-do, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital Yonsei University Health System, Seoul, Not set

Samsung Medical Center, Seoul, Not set

The Catholic University of Korea Seoul St Marys Hospital, Seoul, Not set

VU Medisch Centrum, Amsterdam, Not set

Universitair Medisch Centrum Groningen, Groningen, Not set

Sint Antonius Ziekenhuis - Afd.Interne - INT, Nieuwegein, Not set

Radboudumc, Nijmegen, Not set

Isala Kliniek, Zwolle, Not set

Klinika Hematologii i Transplantologii, UCK, Gdansk, Not set

Pratia Onkologia Katowice, Katowice, Not set

Swietokrzyskie Centrum Onkologii SPZOZ w Kielcach, Kielce, Not set

Centrum Onkologii Ziemi Lubelskiej im sw Jana z Dukli, Lublin, Not set

Specjalistyczny Szpital im dra Alfreda Sokolowskiego w Walbrzychu, Walbrzych, Not set

Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy, Warszawa, Not set

Uniwersytecki Szpital Kliniczny im Jana Mikulicza Radeckiego we Wroclawiu, Wroclaw, Not set

S.P. Botkin Moscow City Clinical Hospital, Moscow, Not set

Clinical Research Institute of Hematology and Transfusiology, St-Petersburg, Not set

Inst. Cat. Doncologia-H Duran I Reynals, Barcelona, Not set

Hosp Univ Vall D Hebron, Barcelona, Not set

Hosp. de Cabuenes, Gijón, Not set

Hosp. Univ. de Gran Canaria Dr. Negrin, Las Palmas de Gran Canaria, Not set

Hosp. Gral. Univ. Gregorio Maranon, Madrid, Not set

Hosp. Univ. Ramon Y Cajal, Madrid, Not set

Hosp. Univ. 12 de Octubre, Madrid, Not set

Hosp. Univ. Son Espases, Palma, Not set

Clinica Univ. de Navarra, Pamplona, Not set

Hosp. Quiron Madrid Pozuelo, Pozuelo de Alarcon, Not set

Hosp Clinico Univ de Salamanca, Salamanca, Not set

Hosp. Univ. Marques de Valdecilla, Santander, Not set

Hosp. Clinico Univ. de Santiago, Santiago de Compostela, Not set

Hosp. Virgen Del Rocio, Sevilla, Not set

Hosp. Univ. I Politecni La Fe, Valencia, Not set

Falu Lasarett, Falun, Not set

Sahlgrenska University Hospital, Göteborg, Not set

Helsingborgs lasarett, Helsingborg, Not set

Sunderby Sjukhus, Luleå, Not set

Skanes universitetssjukhus, Lund, Not set

Norrlands Universitetssjukhus, Umea, Not set

Akademiska Sjukhuset, Uppsala, Not set

China Medical University Hospital, Taichung, Not set

National Cheng Kung University Hospital, Tainan, Not set

Chang Gung Memorial Hospital, Taoyuan, Not set

Ankara University Medical Faculty, Ankara, Not set

Ondokuz Mayis University, Atakum, Not set

Medipol University Hospital, Istanbul, Not set

Dokuz Eylul University Medical Faculty, Izmir, Not set

Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool, Not set

Ninewells Hospital & Medical School, Dundee, Not set

Kings College Hospital, London, Not set

Oxford University Hospitals NHS Foundation Trust, Oxford, Not set

University Hospitals Plymouth NHS Trust, Plymouth, Not set

Royal Marsden Hospital, Sutton, Not set

Conditions: Multiple Myeloma

Learn More ›

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

NCT05552222

Recruiting

The purpose of this study is to compare the efficacy of teclistamab in combination with daratumumab and lenalidomide (Tec-DR) and talquetamab in combination with daratumumab and lenalidomide (Tal-DR) versus daratumumab, lenalidomide, dexamethasone (DRd).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/22/2025

Locations: City of Hope Cancer Center, Duarte, California +206 locations

City of Hope Cancer Center, Duarte, California

City of Hope Orange County Lennar Foundation Cancer Center, Irvine, California

Yale New Haven Hospital, New Haven, Connecticut

University of Iowa Health Care, Waukee, Iowa

Norton Cancer Institute, Louisville, Kentucky

Cancer And Hematology Centers of Western Michigan PC, Grand Rapids, Michigan

Nebraska Cancer Specialists, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

Christus St. Vincent Regional Cancer Center, Santa Fe, New Mexico

Durham VAMC, Durham, North Carolina

Royal Prince Alfred Hospital, Camperdown, Not set

Barwon Health - University Hospital Geelong, Geelong, Not set

Liverpool Hospital, Liverpool, Not set

Sir Charles Gairdner Hospital, Nedlands, Not set

Calvary Mater Newcastle Hospital, New South Wales, Not set

Wollongong Hospital, Wollongong, Not set

Princess Alexandra Hospital, Woolloongabba, Not set

Ordensklinikum Linz GmbH Elisabethinen, Linz, Not set

SCRI CCCIT gem GmbH, Salzburg, Not set

Medical University Vienna, Vienna, Not set

Hanusch Krankenhaus, Wien, Not set

Institut Jules Bordet, Anderlecht, Not set

ZAS Cadix, Antwerpen, Not set

Ghent University Hospital, Gent, Not set

Jolimont, Haine Saint Paul La Louviere, Not set

Az Groeninge, Kortrijk, Not set

Universitair Ziekenhuis Leuven, Leuven, Not set

GZA Ziekenhuizen- Campus St Augustinus, Wilrijk, Not set

Fundacao Pio XII, Barretos, Not set

Santa Casa de Misericordia de Belo Horizonte, Belo Horizonte, Not set

Liga Paranaense de Combate ao Cancer, Curitiba, Not set

Instituto Do Cancer Do Ceara, Fortaleza, Not set

Liga Norte Riograndense Contra O Cancer, Natal, Not set

Complexo Hospitalar de Niteroi, Niteroi, Not set

Hospital De Clinicas De Porto Alegre, Porto Alegre, Not set

Hospital Das Clinicas Da Faculdade De Medicina De RPUSP HCRP, Ribeirao Preto, Not set

Hospital Sao Rafael, Salvador, Not set

Hospital Nove de Julho, Sao Paulo, Not set

Clinica Medica Sao Germano S/S LTDA, Sao Paulo, Not set

Hospital Das Clinicas Da Faculdade De Medicina Da USP, Sao Paulo, Not set

Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta

Cross Cancer Institute, Edmonton, Alberta

British Columbia Cancer Agency, Vancouver, British Columbia

CHU de Quebec L Hotel Dieu de Quebec, Quebec, Not set

Peking Union Medical College Hospital, Beijing, Not set

Peking University First Hospital, Beijing, Not set

Beijing Tongren Hospital CMU, Beijing, Not set

Changzhou No 2 Peoples Hospital, Chang Zhou, Not set

The First Hospital of Jilin University, Changchun, Not set

The Second Xiangya Hospital of Central South Hospital, Changsha, Not set

Beijing Chaoyang Hospital, Chaoyang District, Not set

Sichuan Provincial Peoples Hospital, Chengdu, Not set

Chongqing University Cancer Hospital, Chongqing, Not set

Fujian Meidical University Union Hospital, Fu Zhou, Not set

Nanfang Hospital, Guangzhou, Not set

Sun Yat -Sen University Cancer Center, Guangzhou, Not set

The Second Affiliated Hospital of Zhejiang University, Hang Zhou, Not set

No.1 Affiliated Hospital, Medical College of Zhejiang University, Hangzhou, Not set

Harbin medical university cancer hospital, Harbin, Not set

Qilu Hospital of Shandong University, Jinan, Not set

Zhongda Hospital Southeast University, Nan Jing, Not set

The First Affiliated Hospital of Guangxi Medical University, Nan Ning Shi, Not set

The First Affliated Hospital Of Nanchang University, Nanchang, Not set

Nanjing Drum Tower Hospital, Nanjing, Not set

Ruijin Hospital Shanghai Jiao Tong University, Shanghai, Not set

Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, Not set

Shanghai Fourth People s Hospital, Shanghai, Not set

Peking University Shenzhen Hospital, Shen Zhen Shi, Not set

Shengjing Hospital Of China Medical University, Shenyang, Not set

Institute of Hematology and Blood Diseases Hospital, Tian Jin, Not set

Tianjin Medical University Cancer Institute and Hospital, Tianjin, Not set

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Not set

Wuhan Tongji Hospital Tongji Medical College, WuHan, Not set

The Second Affiliated Hospital of Xi'an Jiaotong University, Xi' An, Not set

The first affiliated hospital of xiamen university, Xiamen, Not set

Henan Cancer Hospital, Zhengzhou, Not set

Fakultni nemocnice Brno, Brno - Bohunice, Not set

Fakultni nemocnice Hradec Kralove, Hradec Kralove, Not set

Fakultni nemocnice Olomouc, Olomouc, Not set

Fakultni Nemocnice Ostrava, Ostrava, Not set

Fakultni nemocnice Plzen, Plzen, Not set

VFN v Praze, Praha, Not set

Aalborg University Hospital, Aalborg, Not set

Regionshospitalet Godstrup, Herning, Not set

Zealand University Hospital, Roskilde, Not set

Vejle Sygehus, Vejle, Not set

APHP - Hopital Henri Mondor, Creteil, Not set

Hopital Claude Huriez, Lille, Not set

CHU Nantes, Nantes, Not set

CHU Hopital Saint Antoine, PARIS cedex 12, Not set

CHU de Bordeaux - Hospital Haut-Leveque, Pessac cedex, Not set

CHU Lyon Sud, Pierre-Benite, Not set

CHU Poitiers - Hopital la Miletrie, Poitiers, Not set

CHU de Rennes - Hopital Pontchaillou, Rennes, Not set

Institut de Cancerologie Strasbourg Europe ICANS, Strasbourg, Not set

Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, Not set

Helios Kliniken Berlin Buch Gmbh, Berlin, Not set

Universitaetsklinikum Halle Saale, Halle (Saale), Not set

Universitaetsklinik Hamburg-Eppendorf, Hamburg, Not set

Klinikum Nuernberg Nord, Nuernberg, Not set

Universitaetsklinikum Tuebingen der Eberhard-Karls-Universitaet, Abteilung fuer Innere Medizin II,, Tübingen, Not set

Universitaetsklinikum Wuerzburg, Wurzburg, Not set

Alexandra General Hospital of Athens, Athens Attica, Not set

G Papanikolaou Hospital of Thessaloniki, Thessalonikis, Not set

Anticancer Hospital of Thessaloniki Theageneio, Thessaloniki, Not set

Rambam Medical Center, Haifa, Not set

Shaare Zedek Medical Center, Jerusalem, Not set

Rabin, Petah Tikva, Not set

Sheba Medical Center, Ramat Gan, Not set

Tel Aviv Sourasky Medical Center, Tel Aviv Yafo, Not set

ASST Papa Giovanni XXIII Bergamo, Bergamo, Not set

A O U Sant Orsola Malpighi, Bologna, Not set

Careggi University Hospital, Firenze, Not set

Ospedale San Raffaele, Milan, Not set

Azienda Ospedaliera di Rilievo Nazionale A Cardarelli, Naples, Not set

IRCCS Policlinico San Matteo, Università degli studi di Pavi, Pavia, Not set

Universita Degli Studi di Roma Tor Vergata, Roma, Not set

Istituto Clinico Humanitas, Rozzano, Not set

Azienda Ospedaliera Universitaria Citta della Salute e della Scienza di Torino, Torino, Not set

Juntendo University Hospital, Bunkyo Ku, Not set

Chiba Cancer Center, Chiba, Not set

Kameda Medical Center, Chiba, Not set

National Hospital Organization Mito Medical Center, Higashiibaraki-gun, Not set

Kansai Medical University Hospital, Hirakata, Not set

Hyogo Medical University Hospital, Hyôgo, Not set

Saitama Medical University Hospital, Iruma-gun, Not set

Tokai University Hospital, Kanagawa, Not set

Kanazawa University Hospital, Kanazawa, Not set

Kumamoto University Hospital, Kumamoto-shi, Not set

Matsuyama Red Cross Hospital, Matsuyama-City, Not set

National Hospital Organization Nagasaki Medical Center, Nagasaki, Not set

National Hospital Organization Okayama Medical Center, Okayama, Not set

Osaka Metropolitan University Hospital, Osaka, Not set

National Hospital Organization Hokkaido Cancer Center, Sapporo, Not set

National Hospital Organization Shibukawa Medical Center, Shibukawa, Not set

Japanese Red Cross Medical Center, Shibuya-ku, Not set

Shizuoka Cancer Center, Sunto Gun, Not set

Fujita Health University Hospital, Toyoake, Not set

Yamagata University Hospital, Yamagata, Not set

Yamanashi Prefectural Central Hospital, Yamanashi, Not set

Dong-A University Hospital, Busan, Not set

Pusan National University Hospital, Busan, Not set

Kyungpook National University Hospital, Daegu, Not set

National Cancer Center, Goyang si, Not set

Chonnam National University Hwasun Hospital, Hwasun, Not set

Gachon University Gil Medical Center, Incheon, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital Yonsei University Health System, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

The Catholic University of Korea Seoul St Mary s Hospital, Seoul, Not set

VUMC Amsterdam, Amsterdam, Not set

Gelre Ziekenhuis, Apeldoorn, Not set

Reinier de Graaf Gasthuis, Delft, Not set

St. Antonius Ziekenhuis Nieuwegein, Nieuwegein, Not set

Zuyderland Medical Center, Sittard-Geleen, Not set

Oslo University Hospital HF Ulleval sykehus, Oslo, Not set

St. Olavs Hospital, Trondheim, Not set

Wojewodzki Szpital Kliniczny w Bialej Podlaskiej, Biala Podlaska, Not set

Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologiczny im Ks B Markiewicza, Brzozow, Not set

Szpital Uniwersytecki nr 2 im. Jana Biziela w Bydgoszczy, Bydgoszcz, Not set

Pratia Onkologia Katowice, Katowice, Not set

Swietokrzyskie Centrum Onkologii SPZOZ w Kielcach, Kielce, Not set

Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im M Kopernika w Lodzi, Lodz, Not set

Centrum Onkologii Ziemi Lubelskiej im sw Jana z Dukli, Lublin, Not set

Uniwersytecki Szpital Kliniczny w Poznaniu, Poznan, Not set

Szpital Uniwersytecki im Karola Marcinkowskiego w Zielonej Gorze, Zielona Gora, Not set

Uls Braga - Hosp. Braga, Braga, Not set

Champalimaud Foundation Champalimaud Centre, Lisbon, Not set

Instituto Portugues de Oncologia, Porto, Not set

Uls Hosp Sao Joao, Porto, Not set

Hosp. Univ. Germans Trias I Pujol, Badalona, Not set

Hosp. de La Santa Creu I Sant Pau, Barcelona, Not set

Hosp Univ Vall D Hebron, Barcelona, Not set

Hosp. Univ. Virgen de Las Nieves, Granada, Not set

Hosp. de Jerez de La Frontera, Jerez de la Frontera, Not set

Hosp. Univ. 12 de Octubre, Madrid, Not set

Hosp. Univ. La Paz, Madrid, Not set

Hosp Univ Hm Sanchinarro, Madrid, Not set

Hosp. Univ. Son Espases, Palma de Mallorca, Not set

Hosp. Quiron Madrid Pozuelo, Pozuelo de Alarcon, Not set

Hosp Clinico Univ de Salamanca, Salamanca, Not set

Hosp. Mutua Terrassa, Terrassa, Not set

Hosp. Clinico Univ. de Valencia, Valencia, Not set

Falu Lasarett, Falun, Not set

Skanes universitetssjukhus, Lund, Not set

Karolinska University Hospital Huddinge, Stockholm, Not set

Universitetssjukhuset Orebro, Örebro, Not set

Inselspital Universitatsspital Bern, Bern, Not set

Kantonsspital St Gallen, St. Gallen, Not set

Dr Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara, Not set

Ankara University Medical Faculty, Ankara, Not set

Liv Hospital Ankara, Ankara, Not set

Memorial Antalya Hospital, Antalya, Not set

Pamukkale University Medical Faculty, Denizli, Not set

Medipol University Hospital, Istanbul, Not set

Dokuz Eylul University Medical Faculty, Izmir, Not set

Ondokuz Mayis University, Samsun, Not set

University Hospitals Birmingham NHS Foundation Trust, Birmingham, Not set

Blackpool Victoria Hospital, Blackpool, Not set

University Hospitals Bristol and Weston, Bristol, Not set

Addenbrooke's Hospital, Cambridge, Not set

Kent and Canterbury Hospital, Canterbury, Not set

Western General Hospital, Edinburgh, Not set

University College London Hospitals, London, Not set

Imperial College Healthcare, London, Not set

New Cross Hospital, Wolverhampton, Not set

Conditions: Multiple Myeloma

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A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

NCT06208150

Recruiting

The purpose of this study is to compare the effectiveness of either talquetamab plus pomalidomide (Tal-P) or talquetamab plus teclistamab (Tal-Tec) with elotuzumab, pomalidomide, and dexamethasone (EPd) or pomalidomide, bortezomib, and dexamethasone (PVd).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/22/2025

Locations: UCSF Fresno, Clovis, California +230 locations

UCSF Fresno, Clovis, California

UCLA, Santa Monica, California

Yale University School Of Medicine, New Haven, Connecticut

Medical Oncology Hematology Consultants, PA, Newark, Delaware

Memorial Healthcare System, Hollywood, Florida

Moffitt Cancer Center, Tampa, Florida

Winship Cancer Institute Emory University, Atlanta, Georgia

Kootenai Health, Coeur d'Alene, Idaho

University of Iowa Health Care, Waukee, Iowa

Norton Cancer Institute, Louisville, Kentucky

Luminis Health Center for Cancer and Blood Disorders, Annapolis, Maryland

University of Maryland School of Medicine, Baltimore, Maryland

The Sidney Kimmel Comprehensive Cancer Center at John Hopkins, Baltimore, Maryland

University of Michigan, Ann Arbor, Michigan

Henry Ford Cancer Institute, Detroit, Michigan

Ascension Providence Hospital, Southfield, Michigan

University Of Minnesota, Minneapolis, Minnesota

Regions Hospital, Saint Paul, Minnesota

University of Nebraska, Omaha, Nebraska

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire

Roswell Park Cancer Institute, Buffalo, New York

Weill Cornell Medical College, New York, New York

SUNY Upstate Medical University, Syracuse, New York

Louis Stokes Cleveland VA Med Ctr, Cleveland, Ohio

Cleveland Clinic, Cleveland, Ohio

Oregon Health And Science University, Portland, Oregon

Penn State Milton S Hershey Medical Ctr, Hershey, Pennsylvania

Thomas Jefferson University, Philadelphia, Pennsylvania

West Penn Hospital, Pittsburgh, Pennsylvania

University Of Pittsburgh Medical Center UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania

Bon Secours Saint Francis Cancer Center, Greenville, South Carolina

UT Southwestern, Dallas, Texas

Houston Methodist Neal Cancer Center at Texas Medical Center, Houston, Texas

Huntsman Cancer Institute, Salt Lake City, Utah

University of Virginia, Charlottesville, Virginia

Swedish Cancer Institute, Seattle, Washington

Fred Hutchinson Cancer Research Center, Seattle, Washington

NorthWest Medical Specialties, PLLC, Tacoma, Washington

Gundersen Health System, La Crosse, Wisconsin

Medical College Of Wisconsin, Milwaukee, Wisconsin

Fundaleu, Buenos Aires, Not set

Hospital Aleman, Buenos Aires, Not set

Hospital Britanico de Buenos Aires, Ciudad Autonoma de Buenos Aires, Not set

Royal Adelaide Hospital, Adelaide, Not set

Box Hill Hospital, Box Hill, Not set

St Vincents Hospital, Darlinghurst, Not set

St Vincents Hospital Melbourne, Fitzroy, Not set

Gold Coast University Hospital, Southport, Not set

Perth Blood Institute, West Perth, Not set

Wollongong Hospital, Wollongong, Not set

LKH - Universitätsklinikum der PMU Salzburg, Salzburg, Not set

Klinik Ottakring, Vienna, Not set

Medical University Vienna MUV, Vienna, Not set

Grand Hopital De Charleroi Site Les Viviers, Charleroi, Not set

Ziekenhuis Oost-Limburg, Genk, Not set

Ghent University Hospital, Gent, Not set

AZ Nikolaas - Campus Sint-Niklaas Moerland, Sint-Niklaas, Not set

Cetus Oncologia, Belo Horizonte, Not set

DF Star, Brasilia, Not set

Fundacao Universidade de Caxias do Sul, Caxias do Sul, Not set

Hospital Erasto Gaertner- Liga Paranaense de Combate ao Cancer, Curitiba, Not set

Hospital De Clinicas De Porto Alegre, Porto Alegre, Not set

Instituto D Or de Pesquisa e Ensino IDOR, Recife, Not set

Instituto de Educacao, Pesquisa e Gestao em Saude Instituto Americas (COI), Rio de Janeiro, Not set

Hospital Sao Rafael, Salvador, Not set

Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto Hospital de Base, Sao Jose do Rio Preto, Not set

Real e Benemerita Associacao Portuguesa de Beneficencia, Sao Paulo, Not set

Fundacao Antonio Prudente A C Camargo Cancer Center, Sao Paulo, Not set

Clinica Medica Sao Germano S/S LTDA, Sao Paulo, Not set

Instituto D Or de Pesquisa e Ensino, Sao Paulo, Not set

Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta

British Columbia Cancer Agency, Vancouver, British Columbia

Nova Scotia Health Authority, Halifax, Nova Scotia

Juravinski Cancer Centre, Hamilton, Ontario

Princess Margaret Cancer Centre University Health Network, Toronto, Ontario

CIUSSS de l Est de l Ile de Montreal Installation Hopital Maisonneuve Rosemont, Montreal, Quebec

Saskatoon Cancer Centre, Saskatoon, Saskatchewan

Beijing Chaoyang Hospital, Beijing, Not set

Peking University First Hospital, Beijing, Not set

Peking University People s Hospital, Beijing, Not set

The Second Xiangya Hospital of Central South Hospital, Changsha, Not set

Changzhou No 2 Peoples Hospital, Changzhou, Not set

Sichuan Provincial Peoples Hospital, Chengdu, Not set

Fujian Meidical University Union Hospital, Fuzhou, Not set

Sun Yat Sen University Cancer Center, Guangzhou, Not set

Nanfang Hospital of Southern Medical Hospital, Guangzhou, Not set

First hospital affiliated of Zhejiang Medical university, Hangzhou, Not set

The Second Affiliated Hospital of Zhejiang University College of Medicine, Hangzhou, Not set

The Affiliated Hospital of Inner Mongolia Medical College, Hu He Hao Te Shi, Not set

Qilu Hospital of Shandong University, Jinan, Not set

The First Affiliated Hospital of Guangxi Medical University, Nan Ning Shi, Not set

The First Affiliated Hospital of NanChang University, Nanchang, Not set

Nanjing Drum Tower Hospital, Nanjing, Not set

Ruijing Hospital Affiliated To Shanghai Jiaotong University School Of Medicine, Shanghai, Not set

Tongji Hospital of Tongji University, Shanghai, Not set

Shanghai Fourth People s Hospital, Shanghai, Not set

Shengjing Hospital Of China Medical University, Shenyang, Not set

Peking University Shenzhen Hospital, Shenzhen, Not set

Shanxi Bethune Hospital, Tai Yuan Shi, Not set

Tianjin Medical University Cancer Institute and Hospital, Tianjin, Not set

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Not set

Tongji Hospital, Tongji Medical College of HUST, Wuhan, Not set

The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Not set

Fakultni nemocnice Brno, Brno - Bohunice, Not set

Fakultni nemocnice Hradec Kralove, Hradec Kralove, Not set

University Hospital Olomouc, Olomouc, Not set

Fakultni Nemocnice Ostrava, Ostrava, Not set

Aarhus University Hospital, Aarhus, Not set

Odense University Hospital, Odense C, Not set

Vejle Hospital, Vejle, Not set

Hopital Claude Huriez, Lille, Not set

CHU de Limoges Hopital Dupuytren, Limoges, Not set

Institut Paoli Calmettes, Marseille, Not set

CHU Nantes, Nantes, Not set

Hopital Saint Louis, Paris, Not set

CHU de Bordeaux - Hospital Haut-Leveque, Pessac Cedex, Not set

CHU Lyon Sud, Pierre Benite, Not set

Institut de Cancerologie Strasbourg Europe ICANS, Strasbourg, Not set

Institut Universitaire du Cancer Toulouse Oncopole, Toulouse Cedex 9, Not set

CHRU Tours Hopital Bretonneau, TOURS Cedex 01, Not set

Klinikum Augsburg, Augsburg, Not set

Universitaetsklinikum Halle Saale, Halle (Saale), Not set

Universitaetsklinikum Heidelberg, Heidelberg, Not set

Universitaetsklinikum Magdeburg A.oe.R, Magdeburg, Not set

Klinikum rechts der Isar der TU Muenchen, München, Not set

Universitaetsklinikum Tuebingen, Tuebingen, Not set

Universitaetsklinikum Wuerzburg, Würzburg, Not set

251 Airforces Hospital, Athens, Not set

Alexandra General Hospital of Athens, Athens, Not set

Anticancer Hospital of Thessaloniki Theageneio, Thessaloniki, Not set

Semmelweis Egyetem, Belgyogyaszati es Hematologiai Klinika, Budapest, Not set

Del Pesti Centrumkorhaz Orszagos Hematologiai es Infektologiai Intezet Szent Laszlo Telephely, Budapest, Not set

Debreceni Egyetem Klinikai Kozpont, Debrecen, Not set

Szabolcs Szatmar Bereg Varmegyei Oktatokorhaz, Nyiregyhaza, Not set

Pecsi Tudomanyegyetem Klinikai Kozpont, Pecs, Not set

Fortis Memorial Research Institute, Gurgaon, Not set

Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Not set

Deenanath Mangeshkar Hospital and Research Centre, Pune, Not set

Shamir Medical Center Assaf Harofeh, Be'er Ya'akov, Not set

Carmel Medical Center, Haifa, Not set

Rabin Medical center - Petah-Tikva, Petah-Tikva, Not set

Sheba Medical Center, Ramat Gan, Not set

Tel Aviv Sourasky Medical Center, Tel Aviv-Yafo, Not set

Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo Alessandria, Alessandria, Not set

A O U Sant Orsola Malpighi, Bologna, Not set

oncologia medica - Oncology, Brindisi, Not set

ARNAS Garibaldi P O Nesima, Catania, Not set

Ospedale Policlinico San Martino IRCCS, Genova, Not set

Asst Ovest Milanese - Ospedale Di Legnano, Legnano, Not set

Fondazione IRCCS Ca Granda Ospedale Policlinico Di Milano, Milano, Not set

IRCCS Ospedale San Raffaele, Milano, Not set

Fondazione IRCCS Policlinico San Matteo, Pavia, Not set

Presidio Ospedaliero Pescara, Pescara, Not set

Ospedale S. Maria Delle Croci, Ravenna, Not set

Oncologia Medica-Città Della Salute E Della Scienza Di Torino, Torino, Not set

Azienda Ospedaliera Universitaria Integrata Verona, Verona, Not set

Juntendo University Hospital, Bunkyo Ku, Not set

Fukuoka University Hospital, Fukuoka, Not set

Hamamatsu University Hospital, Hamamatsu, Not set

Kanazawa University Hospital, Kanazawa, Not set

University Hospital Kyoto Prefectural University of Medicine, Kyoto, Not set

National Hospital Organization Nagasaki Medical Center, Nagasaki, Not set

Japanese Red Cross Narita Hospital, Narita, Not set

Niigata Cancer Center Hospital, Niigata, Not set

Hyogo Medical University Hospital, Nishinomiya shi, Not set

Japanese Red Cross Osaka Hospital, Osaka, Not set

Sapporo City General Hospital, Sapporo, Not set

Tohoku University Hospital, Sendai, Not set

Japanese Red Cross Medical Center, Shibuya-ku, Not set

Iwate Medical University Hospital, Shiwa-gun, Not set

The University of Osaka Hospital, Suita City, Not set

Shizuoka Cancer Center, Sunto Gun, Not set

The Cancer Institute Hospital of JFCR, Tokyo, Not set

Tottori University Hospital, Tottori, Not set

University of Tsukuba Hospital, Tsukuba, Not set

Kanagawa Cancer Center, Yokohama City, Not set

Dong-A University Hospital, Busan, Not set

Pusan National University Hospital, Busan, Not set

Chonnam National University Hwasun Hospital, Jeollanam-do, Not set

Seoul National University Hospital, Seoul, Not set

Samsung Medical Center, Seoul, Not set

The Catholic University of Korea Seoul St Mary s Hospital, Seoul, Not set

Ulsan University Hospital, Ulsan, Not set

Centro de Quimioterapia e Investigacion, Guadalajara, Not set

Hematologica Alta Especialidad, Huixquilucan, Not set

Hospital Universitario Dr Jose Eleuterio Gonzalez, Monterrey, Not set

Flevoziekenhuis, Almere, Not set

Haga ziekenhuis, Den Haag, Not set

Catharinaziekenhuis, Eindhoven, Not set

St. Antonius Ziekenhuis Nieuwegein, Nieuwegein, Not set

Isala Kliniek, Zwolle, Not set

Wojewodzki Szpital Specjalistyczny, Biala Podlaska, Not set

Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologiczny im Ks B Markiewicza, Brzozow, Not set

Swietokrzyskie Centrum Onkologii SPZOZ w Kielcach, Kielce, Not set

Centrum Onkologii Ziemii Lubelskiej, Lublin, Not set

Uniwersytecki Szpital Kliniczny Nr 1 PUM im prof Tadeusza Sokolowskiego w Szczecinie, Szczecin, Not set

Uniwersytecki Szpital Kliniczny im Jana Mikulicza Radeckiego we Wroclawiu, Wroclaw, Not set

King Abdullah International Medical Research Center (KAIMRC), Riyadh, Not set

King Faisal Specialist Hospital & Research Center, Riyadh, Not set

King Fahad Medical City, Riyadh, Not set

Hosp. de Cabuenes, Asturias, Not set

Hosp Univ Vall D Hebron, Barcelona, Not set

Hosp. Univ. de Burgos, Burgos, Not set

Hosp. San Pedro de Alcantara, Cáceres, Not set

Hosp. Univ. Virgen de Las Nieves, Granada, Not set

Hosp. Univ. Lucus Augusti, Lugo, Not set

Hosp. Univ. La Paz, Madrid, Not set

Hosp. Univ. Son Espases, Palma de Mallorca, Not set

Clinica Univ. de Navarra, Pamplona, Not set

Complejo Hosp de Navarra - Hosp de Navarra, Pamplona, Not set

Hosp Clinico Univ de Salamanca, Salamanca, Not set

Hosp. Univ. Donostia, San Sebastian, Not set

Hosp. Univ. Marques de Valdecilla, Santander, Not set

Hosp. Clinico Univ. de Santiago, Santiago de Compostela, Not set

Skanes universitetssjukhus, Lund, Not set

Norrlands Universitetssjukhus, Umea, Not set

Akademiska Sjukhuset, Uppsala, Not set

Varberg Hospital, Varberg, Not set

Ankara University Medical Faculty, Ankara, Not set

Liv Hospital Ankara, Ankara, Not set

Pamukkale University Medical Faculty, Denizli, Not set

Medipol University Hospital, Istanbul, Not set

Ondokuz Mayis University, Samsun, Not set

Blackpool Victoria Hospital, Blackpool, Not set

University Hospital of Wales, Cardiff, Not set

Ninewells Hospital, Dundee, Not set

St James University Hospital, Leeds, Not set

Kings College Hospital, London, Not set

Nottingham City Hospital, Nottingham, Not set

University Hospitals Plymouth NHS Trust, Plymouth, Not set

Queen Alexandra Hospital, Portsmouth, Not set

Conditions: Relapsed or Refractory Multiple Myeloma

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A Study of Combination of Daratumumab and Velcade (Bortezomib) Melphalan-Prednisone (DVMP) Compared to Velcade Melphalan-Prednisone (VMP) in Participants With Previously Untreated Multiple Myeloma

NCT02195479

Completed

The purpose of this study is to determine if the addition of daratumumab to velcade (bortezomib) melphalan-prednisone (VMP) will prolong progression-free survival (PFS) compared with VMP alone in participants with previously untreated multiple myeloma who are ineligible for high dose chemotherapy and autologous stem cell transplant (ASCT).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/22/2025

Locations: Not set, California City, California +163 locations

Not set, California City, California

Not set, Corona, California

Not set, Fountain Valley, California

Not set, Los Angeles, California

Not set, Hialeah, Florida

Not set, Orange Park, Florida

Not set, Chicago, Illinois

Not set, Springfield, Missouri

Not set, Cleveland, Ohio

Not set, Fredericksburg, Virginia

Not set, Buenos Aires, Not set

Not set, Ciudad Autonoma Buenos Aires, Not set

Not set, Córdoba, Not set

Not set, Santa Fe, Not set

Not set, Adelaide, Not set

Not set, Bendigo, Not set

Not set, Camperdown N/a, Not set

Not set, Geelong, Not set

Not set, Gosford, Not set

Not set, Greenslopes, Not set

Not set, Hobart, Not set

Not set, North Adelaide, Not set

Not set, Parkville, Not set

Not set, Antwerpen, Not set

Not set, Antwerp, Not set

Not set, Brussel, Not set

Not set, Charleroi, Not set

Not set, Gent, Not set

Not set, Kortrijk, Not set

Not set, Roeselare, Not set

Not set, Turnhout, Not set

Not set, Yvoir, Not set

Not set, Barretos, Not set

Not set, Cuiaba - Mount, Not set

Not set, Fortaleza, Not set

Not set, Goiania, Not set

Not set, Natal, Not set

Not set, Porto Alegre, Not set

Not set, Ribeirao Preto, Not set

Not set, Rio de Janeiro, Not set

Not set, Sao Paulo, Not set

Not set, Pleven, Not set

Not set, Plovdiv, Not set

Not set, Sofia, Not set

Not set, Varna, Not set

Not set, Vratsa, Not set

Not set, Zadar, Not set

Not set, Zagreb, Not set

Not set, Brno, Not set

Not set, Hradec Kralove, Not set

Not set, Olomouc, Not set

Not set, Ostrava-Poruba, Not set

Not set, Praha 10, Not set

Not set, Praha 2, Not set

Not set, Tbilisi, Not set

Not set, Berlin, Not set

Not set, Dortmund, Not set

Not set, Karlsruhe, Not set

Not set, Potsdam, Not set

Not set, Saarbrücken, Not set

Not set, Stuttgart, Not set

Not set, Würzburg, Not set

Not set, Athens Attica, Not set

Not set, Athens, Not set

Not set, Patra, Not set

Not set, Thessaloniki, Not set

Not set, Budapest, Not set

Not set, Debrecen, Not set

Not set, Kaposvar, Not set

Not set, Pecs N/a, Not set

Not set, Chiba, Not set

Not set, Hitachi, Not set

Not set, Kanazawa, Not set

Not set, Kawasaki, Not set

Not set, Kobe, Not set

Not set, Kurume, Not set

Not set, Matsuyama, Not set

Not set, Nagoya, Not set

Not set, Narita, Not set

Not set, Ohgaki, Not set

Not set, Okayama, Not set

Not set, Osaka, Not set

Not set, Sendai-shi, Not set

Not set, Shibukawa, Not set

Not set, Shibuya, Not set

Not set, Tachikawa, Not set

Not set, Toyohashi, Not set

Not set, Busan, Not set

Not set, Gyeonggi-do, Not set

Not set, Hwasun, Not set

Not set, Incheon, Not set

Not set, Seongnam, Not set

Not set, Seoul, Not set

Not set, Skopje, Not set

Not set, Bialystok, Not set

Not set, Bydgoszcz, Not set

Not set, Chorzow, Not set

Not set, Gdansk, Not set

Not set, Legnica, Not set

Not set, Lublin, Not set

Not set, Opole, Not set

Not set, Slupsk, Not set

Not set, Warszawa Ul, Not set

Not set, Warszawa, Not set

Not set, Wroclaw, Not set

Not set, Lisboa, Not set

Not set, Lisbon, Not set

Not set, Porto, Not set

Not set, Brasov, Not set

Not set, Bucharest, Not set

Not set, Iasi, Not set

Not set, Arkhangelsk, Not set

Not set, Dzerzhinsk, Not set

Not set, Ekaterinbourg, Not set

Not set, Nizhny Novgorod, Not set

Not set, Ryazan, Not set

Not set, Saint-Petersburg, Not set

Not set, Saratov, Not set

Not set, Sochi, Not set

Not set, St Petersburg, Not set

Not set, Volgograd, Not set

Not set, Belgrade, Not set

Not set, Nis, Not set

Not set, Novi Sad, Not set

Not set, Sremska Kamenica, Not set

Not set, Zemun, Not set

Not set, Andalucía, Not set

Not set, Badalona, Not set

Not set, Barcelona, Not set

Not set, Córdoba, Not set

Not set, Girona, Not set

Not set, La Laguna, Not set

Not set, Madrid, Not set

Not set, Maranon, Not set

Not set, Murcia N/a, Not set

Not set, Ourense, Not set

Not set, Pamplona, Not set

Not set, Salamanca, Not set

Not set, Sevilla, Not set

Not set, Toledo, Not set

Not set, Valencia, Not set

Not set, Zaragoza, Not set

Not set, Altindag, Not set

Not set, Ankara, Not set

Not set, Aydin, Not set

Not set, Izmir, Not set

Not set, Kayseri, Not set

Not set, Samsun, Not set

Not set, Tekirdag, Not set

Not set, Cherkassy, Not set

Not set, Dnepropetrovsk, Not set

Not set, Ivano-Frankivsk, Not set

Not set, Kharkov, Not set

Not set, Khmelnitskiy, Not set

Not set, Lviv, Not set

Not set, Zaporizhzhia, Not set

Not set, Birmingham, Not set

Not set, Cambridge, Not set

Not set, Colchester, Not set

Not set, Harlow, Not set

Not set, Leicester, Not set

Not set, London, Not set

Not set, Manchester, Not set

Not set, Woolwich, Not set

Conditions: Multiple Myeloma

Learn More ›

A Study to Evaluate the Efficacy and Safety of Daratumumab in Combination With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to CyBorD Alone in Newly Diagnosed Systemic Amyloid Light-chain (AL) Amyloidosis

NCT03201965

Completed

The purpose of this study is to evaluate the efficacy and safety of daratumumab plus cyclophosphamide, bortezomib and dexamethasone (CyBorD) compared with CyBorD alone in treatment of newly diagnosed amyloid light chain (AL) amyloidosis participants.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/22/2025

Locations: Mayo Clinic Arizona, Phoenix, Arizona +139 locations

Mayo Clinic Arizona, Phoenix, Arizona

City of Hope, Duarte, California

University of California San Francisco, San Francisco, California

Stanford University, Stanford, California

University of Colorado, Aurora, Colorado

Colorado Blood Cancer Institute, Denver, Colorado

Mayo Clinic, Jacksonville, Florida

Winship Cancer Institute Emory University, Atlanta, Georgia

University of Maryland, Baltimore, Maryland

Tufts Medical Center, Boston, Massachusetts

Boston University Medical Center, Boston, Massachusetts

Dana Farber Cancer Institute, Boston, Massachusetts

Barbara Ann Karmanos Cancer Institute, Detroit, Michigan

Mayo Clinic Rochester, Rochester, Minnesota

Washington University School Of Medicine, Saint Louis, Missouri

Columbia University Medical Center, New York, New York

Weill Cornell Medical College, New York, New York

University of Rochester Medical Center, Rochester, New York

Levine Cancer Institute, Charlotte, North Carolina

Wake Forest University Health Sciences - Cardiovascular Medicine, Winston-Salem, North Carolina

Cleveland Clinic, Cleveland, Ohio

The Ohio State University, Columbus, Ohio

Oregon Health And Science University, Portland, Oregon

University of Pennsylvania Medical Center, Philadelphia, Pennsylvania

Sarah Cannon Research Institute, Nashville, Tennessee

Vanderbilt University Medical Center, Nashville, Tennessee

University of Texas, MD Anderson Cancer Center, Houston, Texas

Huntsman Cancer Institute, Salt Lake City, Utah

Seattle Cancer Care Alliance, Seattle, Washington

Box Hill Hospital, Box Hill, Not set

Sir Charles Gairdner Hospital, Nedlands, Not set

Westmead Hospital, Westmead, Not set

Princess Alexandra Hospital, Woolloongabba, Not set

Institut Jules Bordet, Anderlecht, Not set

UZ Gent, Gent, Not set

Az Groeninge, Kortrijk, Not set

Universitair Ziekenhuis Leuven, Leuven, Not set

Hospital das Clinicas de Porto Alegre, Porto Alegre, Not set

Sociedade Pernambucana de Combate ao Cancer, Recife, Not set

Instituto de Educacao, Pesquisa e Gestao em Saude Instituto Americas (COI), Rio de Janeiro, Not set

Hospital Sao Rafael, Salvador, Not set

Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto Hospital de Base, Sao Jose do Rio Preto, Not set

Instituto de Assistencia Medica ao Servidor Publico Estadual IAMSPE, Sao Paulo, Not set

Clinica Sao Germano, São Paulo, Not set

Hospital Das Clinicas Da Faculdade De Medicina Da USP, São Paulo, Not set

Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta

Alberta Health Services, Edmonton, Alberta

Vancouver General Hospital, Vancouver, British Columbia

London Health Sciences Center, London, Ontario

University Health Network UHN Princess Margaret Cancer Centre, Toronto, Ontario

McGill University Health Centre, Montreal, Quebec

Peking University First Hospital, Beijing, Not set

Peking University People s Hospital, Beijing, Not set

First affiliated Hospital of Zhejiang University, Hangzhou, Not set

Ruijin Hospital Shanghai Jiao Tong University, Shanghai, Not set

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Not set

Aarhus University Hospital, Aarhus N, Not set

Dep. of Hematology, Rigshospitalet, Copenhagen, Not set

Odense Universitets Hospital, Odense, Not set

CHU Dijon, Dijon, Not set

Hopital Claude Huriez, Lille cedex, Not set

CHU de Limoges - Fédération Hépatologie, Limoges, Not set

Institut Paoli Calmettes, Marseille, Not set

Chu Hotel Dieu, Nantes cedex 01, Not set

Hopital Saint Louis, PARIS cedex 10, Not set

Centre hospitalier Lyon-Sud, Pierre - Bénite cedex, Not set

CHU De Poitiers, Poitiers, Not set

CHU Rangueil, Toulouse, Not set

CHU Bretonneau, Tours cedex, Not set

CHU de Nancy_ Hopital Brabois, Vandoeuvre les Nancy, Not set

Charite Campus Benjamin Franklin, Berlin, Not set

Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Not set

Universitatsklinikum Essen, Essen, Not set

HOPA-Hämatologisch-Onkologische Praxis Altona MVZ GmbH, Hamburg, Not set

Universitaetsklinikum Heidelberg Medizinische Klinik V, Heidelberg, Not set

Universitaetsklinikum Tuebingen der Eberhard-Karls-Universitaet, Abteilung fuer Innere Medizin II,, Tübingen, Not set

Universitätsklinikum Würzburg Med. Klinik U. Poliklinik Ii, Würzburg, Not set

Alexandra General Hospital of Athens, Athens, Not set

University General Hospital of Rio, Patra, Not set

Semmelweis Egyetem I.Belgyogyaszati Klinika, Budapest, Not set

Del Pesti Centrumkorhaz Orszagos Hematologiai es Infektologiai Intezet Szent Laszlo Telephely, Budapest, Not set

Carmel Hospital, Haifa, Not set

Hadassah Medical Center, Jerusalem, Not set

Sheba Medical Center, Ramat-Gan, Not set

Sourasky Medical Center, Tel-Aviv, Not set

Assaf Ha'Rofeh Medical Center, Zerifin, Not set

Policlinico di Bari, Bari, Not set

Istituto di Ematologia Seràgnoli azienda ospedaliera univeristaria Policlinico S.Orsola-Malpighi, Bologna, Not set

Casa di Cura La Maddalena, Palermo, Not set

Amyloidosis Research and Treatment Center, Fondazione IRCCS Policlinico San Matteo, Pavia, Not set

Dipartimento Di Biotecnologie Cellulari Ed Ematologia-Università ''La Sapienza'',Policlinico Umberto I, Roma, Not set

A.O.U. Città della Salute e della Scienza, Torino, Not set

Fukushima Medical University Hospital, Fukushima, Not set

Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital, Hiroshima, Not set

Teine Keijinkai Hospital, Hokkaido, Not set

Kanazawa University Hospital, Kanazawa, Not set

Kumamoto University Hospital, Kumamoto-City, Not set

Kyoto Kuramaguchi Medical Center, Kyoto, Not set

Shinshu University Hospital, Matsumoto, Not set

Matsuyama Red Cross Hospital, Matsuyama, Not set

Nagoya City University Hospital, Nagoya, Not set

National Hospital Organization Okayama Medical Center, Okayama, Not set

Japanese Red Cross Medical Center, Shibuya, Not set

Tokushima University Hospital, Tokushima, Not set

Pusan National University Hospital, Busan, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital Yonsei University Health System, Seoul, Not set

Samsung Medical Center, Seoul, Not set

The Catholic University of Korea Seoul St Marys Hospital, Seoul, Not set

Centro de Investigación Farmacéutica Especializada, Guadalajara, Not set

Hospital Universitario Dr Jose Eleuterio Gonzalez, Monterrey, Not set

Haga ziekenhuis, Den Haag, Not set

UMCG, Groningen, Not set

Erasmus MC, Rotterdam, Not set

UMC Utrecht, Utrecht, Not set

Maxima Medisch Centrum, Veldhoven, Not set

Samodzielny Publiczny Zaklad Opieki Zdrowotnej Zespol Szpitali Miejskich, Chorzow, Not set

SKPP UM w Poznaniu, Poznan, Not set

Instytut Hematologii i Transfuzjologii, Warszawa, Not set

Inst. Cat. D'Oncologia-Badalona, Badalona, Not set

Hosp Univ Vall D Hebron, Barcelona, Not set

Hosp Clinic de Barcelona, Barcelona, Not set

Hosp. Univ. Ramon Y Cajal, Madrid, Not set

Hosp Univ Fund Jimenez Diaz, Madrid, Not set

Hosp. Univ. 12 de Octubre, Madrid, Not set

Clinica Univ. de Navarra, Pamplona, Not set

Hosp Clinico Univ de Salamanca, Salamanca, Not set

Hosp. Univ. de Canarias, San Cristóbal de La Laguna, Not set

Hosp. Univ. Dr. Peset, Valencia, Not set

South Elvsborg Hospital, Boras, Not set

Skanes universitetssjukhus, Lund, Not set

Ankara Universitesi Tip Fakultesi Cebeci Hastanesi, Ankara, Not set

Akdeniz University Medical Faculty, Antalya, Not set

Ondokuz Mayis Universitesi Tip Fakultesiy, Atakum, Not set

Istanbul University Istanbul Medical Faculty, Istanbul, Not set

Dokuz Eylul Universitesi Tip Fakultesi, Izmir, Not set

Erciyes University Medical Faculty, Talas, Not set

University Hospitals Birmingham NHS Trust,, Birmingham, Not set

University College Hospital, London, Not set

Conditions: Amyloidosis

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A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy

NCT04923893

Active Not Recruiting

The purpose of this study is to compare the efficacy of Bortezomib, Lenalidomide and Dexamethasone (VRd) induction followed by a single administration of ciltacabtagene autoleucel (cilta-cel) versus VRd induction followed by Lenalidomide and Dexamethasone (Rd) maintenance in newly diagnosed multiple myeloma participants for whom ASCT is not planned as initial therapy in terms of Progression Free Survival (PFS).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/22/2025

Locations: UCSF, San Francisco, California +135 locations

UCSF, San Francisco, California

Yale Cancer Center, New Haven, Connecticut

University of Miami Health System, Miami, Florida

AdventHealth Cancer Institute, Orlando, Florida

University of Iowa Hospitals and Clinics, Iowa City, Iowa

University of Kentucky, Lexington, Kentucky

Norton Cancer Institute, Louisville, Kentucky

University Of Maryland Medical Center, Baltimore, Maryland

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Barbara Ann Karmanos Cancer Institute, Detroit, Michigan

Henry Ford Cancer Institute, Detroit, Michigan

Columbia University Medical Center, New York, New York

Memorial Sloan-Kettering Cancer Center, New York, New York

New York Presbyterian-Weill Cornell Medical College, New York, New York

Levine Cancer Institute, Charlotte, North Carolina

Thomas Jefferson University, Philadelphia, Pennsylvania

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania

University of Virginia, Charlottesville, Virginia

Medical College Of Wisconsin, Milwaukee, Wisconsin

Hospital Aleman, Buenos Aires, Not set

Hospital Italiano de Buenos Aires, Buenos Aires, Not set

Hospital Privado Universitario De Cordoba, Cordoba, Not set

Royal Prince Alfred Hospital, Camperdown, Not set

St Vincents Hospital Melbourne, Fitzroy, Not set

Austin Health, Heidelberg, Not set

Royal Brisbane and Womens Hospital, Herston, Not set

Alfred Health, Melbourne, Not set

Peter MacCallum Cancer Centre, Melbourne, Not set

Fiona Stanley Hospital, Murdoch, Not set

Calvary Mater Newcastle Hospital, Waratah, Not set

Western Sydney Local Health District, Westmead, Not set

Medizinische Universität Graz, LKH-Univ.Klinikum Graz, Klinische Abteilung für Hämatologie, Graz, Not set

Krankenhaus der Elisabethinen Linz, Linz, Not set

LKH - Universitätsklinikum der PMU Salzburg, Salzburg, Not set

Medical University of Vienna Universitatsklinik fur Innere Medizin I, Vienna, Not set

Universitair Ziekenhuis - Antwerpen, Antwerp, Not set

AZ St.-Jan Brugge-Oostende AV, Brugge, Not set

UZ Gent, Gent, Not set

UZ Leuven, Leuven, Not set

Centre Hospitalier Universitaire de Liege Domaine Universitaire du Sart Tilman, Liege, Not set

Hospital Sao Rafael, Salvador, Not set

Fundacao Antonio Prudente A C Camargo Cancer Center, Sao Paulo, Not set

Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein, Sao Paulo, Not set

Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta

Vancouver General Hospital, Vancouver, British Columbia

Juravinski Cancer Centre, Hamilton, Ontario

Princess Margaret Cancer Centre University Health Network, Toronto, Ontario

Hopital Maisonneuve Rosemont, Montreal, Quebec

Fakultni nemocnice Brno, Brno, Not set

Fakultni nemocnice Hradec Kralove, Hradec Kralove, Not set

Fakultni Nemocnice Ostrava, Ostrava - Poruba, Not set

Vseobecna fakultni nemocnice v Praze, Praha 2, Not set

Aarhus University Hospital, Aarhus C, Not set

Rigshospitalet, Copenhagen, Not set

Odense Universitetshospital, Odense C, Not set

Helsinki University Hospital, Helsinki, Not set

Oulu University Hospital, Oulu, Not set

Turku University Hospital, Turku, Not set

Centre Hospitalier Régional Universitaire de Lille, Hôpital Claude Huriez, Lille Cedex, Not set

C.H.U. Hotel Dieu - France, Nantes, Not set

Hopital Saint Louis, Paris cedex 10, Not set

CHU Poitiers - Hopital la Miletrie, Poitiers, Not set

Institut Universitaire du cancer de Toulouse-Oncopole, Toulouse cedex 9, Not set

Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Not set

Universitaetsklinikum Carl Gustav Carus TU Dresden, Dresden, Not set

Universitatsklinikum Freiburg, Freiburg, Not set

Universitaetsklinikum Hamburg Eppendorf, Hamburg, Not set

Universitaetsklinikum Heidelberg, Heidelberg, Not set

Universitaetsklinikum Leipzig, Leipzig, Not set

Universitatsmedizin der Johannes Gutenberg Universitat Mainz, Mainz, Not set

Klinikum Großhadern der Ludwig-Maximilians-Universität, München, Not set

Universitaetsklinikum Regensburg, Regensburg, Not set

Klinikum der Eberhard Karls Universitaet Abt fur innere Med II Haematologie Onkologie Germany, Tubingen, Not set

Universitatsklinikum Wurzburg, Wuerzburg, Not set

Alexandra General Hospital of Athens, Athens, Not set

Attikon University General Hospital of Attica, Athens, Not set

G.Papanikolaou, Thessaloniki, Not set

Del Pesti Centrumkorhaz Orszagos Hematologiai es Infektologiai Intezet Szent Laszlo Telephely, Budapest, Not set

Debreceni Egyetem Klinikai Kozpont, Debrecen, Not set

St James Hospital, Dublin, Not set

Hadassah University Hospita Ein Kerem, Jerusalem, Not set

Sheba Medical Center Tel Hashomer, Ramat Gan, Not set

Tel Aviv Sourasky Medical Center, Tel Aviv, Not set

Juntendo University Hospital, Bunkyo Ku, Not set

Kyushu University Hospital, Fukuoka, Not set

Hyogo Medical University Hospital, Hyôgo, Not set

Kanazawa University Hospital, Kanazawa, Not set

University Hospital Kyoto Prefectural University of Medicine, Kyoto, Not set

Nagoya City University Hospital, Nagoya, Not set

Okayama University Hospital, Okayama, Not set

Hokkaido University Hospital, Sapporo, Not set

Tohoku University Hospital, Sendai, Not set

Japanese Red Cross Medical Center, Shibuya, Not set

Chonnam National University Hwasun Hospital, Jeollanam-do, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital Yonsei University Health System, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

The Catholic University of Korea Seoul St Marys Hospital, Seoul, Not set

VU Medisch Centrum, Amsterdam, Not set

University Medical Center Groningen, Groningen, Not set

UMC Radboud, Nijmegen, Not set

Erasmus MC, Rotterdam, Not set

Oslo universitetssykehus HF, Rikshospitalet, Oslo, Not set

Uniwersyteckie Centrum Kliniczne, Gdansk, Not set

Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut BadawczyOddz w Gliwicach, Gliwice, Not set

Centrum Onkologii Ziemi Lubelskiej im sw Jana z Dukli, Lublin, Not set

Uniwersytecki Szpital Kliniczny w Poznaniu, Poznan, Not set

Instytut Hematologii i Transfuzjologii, Warszawa, Not set

Uniwersytecki Szpital Kliniczny im Jana Mikulicza Radeckiego we Wroclawiu, Wroclaw, Not set

Instituto Portugues de Oncologia, Lisboa, Not set

Instituto Portugues de Oncologia, Porto, Not set

Hosp. de La Santa Creu I Sant Pau, Barcelona, Not set

Hosp Univ Vall D Hebron, Barcelona, Not set

Instituto Catalan Deoncologia Hospital Duran I Reynals, L'Hospitalet de Llobregat, Not set

Hosp. Gral. Univ. Gregorio Maranon, Madrid, Not set

Hosp. Univ. 12 de Octubre, Madrid, Not set

Hosp. Univ. Virgen de La Arrixaca, Murcia, Not set

Clinica Univ. de Navarra, Pamplona, Not set

Hosp Clinico Univ de Salamanca, Salamanca, Not set

Hosp. Univ. Marques de Valdecilla, Santander, Not set

Hosp. Virgen Del Rocio, Sevilla, Not set

Hosp. Univ. I Politecni La Fe, Valencia, Not set

Sahlgrenska University Hospital, Goteborg, Not set

Universitetssjukhuset, Linköping, Not set

Skane University Hospital, Lund, Not set

Universitatsspital Basel, Basel, Not set

Inselspital Universitatsspital Bern, Bern, Not set

Kantonsspital St Gallen, St. Gallen, Not set

University Hospitals Birmingham NHS Trust,, Birmingham, Not set

Bristol Royal Infirmary, Bristol, Not set

Leeds Teaching Hospitals NHS Trust, Leeds, Not set

University College Hospital, London, Not set

Kings College Hospital, London, Not set

Manchester Royal Infirmary, Manchester, Not set

The Royal Marsden NHS Trust Sutton, Surrey, Not set

Conditions: Multiple Myeloma

Learn More ›

A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis (CARES)

NCT04504825

Active Not Recruiting

AL (or light chain) amyloidosis begins in the bone marrow where abnormal proteins misfold and create free light chains that cannot be broken down. These free light chains bind together to form amyloid fibrils that build up in the extracellular space of organs, affecting the kidneys, heart, liver, spleen, nervous system and digestive tract. The primary purpose of this study is to determine whether CAEL-101, a monoclonal antibody that removes AL amyloid deposits from tissues and organs, improves... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/22/2025

Locations: Research Site, Duarte, California +89 locations

Research Site, Duarte, California

Research Site, Palo Alto, California

Research Site, San Francisco, California

Research Site, Weston, Florida

Research Site, Indianapolis, Indiana

Research Site, New Orleans, Louisiana

Research Site, Boston, Massachusetts

Research Site, Detroit, Michigan

Research Site, Rochester, Minnesota

Research Site, Saint Louis, Missouri

Research Site, New York, New York

Research Site, Rochester, New York

Research Site, Winston-Salem, North Carolina

Research Site, Cleveland, Ohio

Research Site, Columbus, Ohio

Research Site, Portland, Oregon

Research Site, Philadelphia, Pennsylvania

Research Site, Nashville, Tennessee

Research Site, Dallas, Texas

Research Site, Houston, Texas

Research Site, Salt Lake City, Utah

Research Site, Seattle, Washington

Research Site, Milwaukee, Wisconsin

Research Site, Box Hill, Not set

Research Site, Brisbane, Not set

Research Site, Westmead, Not set

Research Site, Linz, Not set

Research Site, Vienna, Not set

Research Site, Anderlecht, Not set

Research Site, Leuven, Not set

Research Site, Porto Alegre, Not set

Research Site, Ribeirão Preto, Not set

Research Site, S.J. Do Rio Preto, Not set

Research Site, Salvador, Not set

Research Site, Calgary, Alberta

Research Site, Edmonton, Alberta

Research Site, Toronto, Ontario

Research Site, Beijing, Not set

Research Site, Guangzhou, Not set

Research Site, Hangzhou, Not set

Research Site, Wenzhou, Not set

Research Site, Wuhan, Not set

Research Site, Ostrava - Poruba, Not set

Research Site, Prague, Not set

Research Site, Caen, Not set

Research Site, Creteil, Not set

Research Site, Limoges, Not set

Research Site, Marseille, Not set

Research Site, Paris, Not set

Research Site, Pessac, Not set

Research Site, Pierre-Benite, Not set

Research Site, Poitiers, Not set

Research Site, Rennes, Not set

Research Site, Toulouse, Not set

Research Site, Tours, Not set

Research Site, Berlin, Not set

Research Site, Duesseldorf, Not set

Research Site, Essen, Not set

Research Site, Hamburg, Not set

Research Site, Heidelberg, Not set

Research Site, Wuerzburg, Not set

Research Site, Athens, Not set

Research Site, Rio, Not set

Research Site, Haifa, Not set

Research Site, Jerusalem, Not set

Research Site, Tel Hashomer, Not set

Research Site, Napoli, Not set

Research Site, Pavia, Not set

Research Site, Pisa, Not set

Research Site, Roma, Not set

Research Site, Fukushima-shi, Not set

Research Site, Nagoya-shi, Not set

Research Site, Shibuya-ku, Not set

Research Site, Seoul, Not set

Research Site, Groningen, Not set

Research Site, Utrecht, Not set

Research Site, Gdańsk, Not set

Research Site, Poznan, Not set

Research Site, Warszawa, Not set

Research Site, Barcelona, Not set

Research Site, Gijón, Not set

Research Site, Majadahonda, Not set

Research Site, Pamplona, Not set

Research Site, Sevilla, Not set

Research Site, London, Not set

Conditions: AL Amyloidosis

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A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma

NCT06577025

Recruiting

The purpose of this study is to evaluate the rate of response (how effectively treatment is working) with signs of potential cure at 5 years after the start of induction treatment. This is defined as a composite of sustained (at least 2 years) minimal residual disease (MRD) negativity with complete response/stringent complete response (CR/sCR) and a positron emission tomography/computed tomography (PET/CT) scan that does not show any signs of cancer at 5 years. MRD negativity and CR/sCR is defin... Read More

Gender:

ALL

Ages:

Between 18 years and 70 years

Trial Updated:

05/22/2025

Locations: City of Hope, Duarte, California +14 locations

Conditions: Multiple Myeloma

Learn More ›

A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis

NCT05250973

Recruiting

The purpose of this study is to characterize cardiac safety of Daratumumab, Cyclophosphamide, Bortezomib, and Dexamethasone (D-VCd) treatment regimens (Arm A: daratumumab + immediate VCd treatment and Arm B: daratumumab + deferred VCd) in newly diagnosed systemic amyloid light chain (AL) amyloidosis with cardiac involvement and to identify potential mitigation strategies for cardiac toxicity (cohort 1); to characterize the pharmacokinetics of subcutaneous (SC) daratumumab, among racial and ethni... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/22/2025

Locations: City of Hope, Duarte, California +45 locations

City of Hope, Duarte, California

Smilow Cancer Hospital/Yale Cancer Center, New Haven, Connecticut

Moffitt Cancer Center, Tampa, Florida

Winship Cancer Institute Emory University, Atlanta, Georgia

Tufts Medical Center, Boston, Massachusetts

Boston University Medical Center, Boston, Massachusetts

Barbara Ann Karmanos Cancer Institute, Detroit, Michigan

Memorial Sloan Kettering, New York, New York

Levine Cancer Institute, Charlotte, North Carolina

Wake Forest University - Baptist Medical Center, Winston-Salem, North Carolina

University Hospital of Cleveland, Cleveland, Ohio

Ohio Health Research Institute, Columbus, Ohio

West Penn Hospital, Pittsburgh, Pennsylvania

UT Southwestern Medical Center, Dallas, Texas

VCU Medical Center, Richmond, Virginia

University of Washington, Seattle, Washington

Tom Baker Cancer Center, Calgary, Alberta

Cross Cancer Institute, Edmonton, Alberta

University Health Network UHN Princess Margaret Cancer Centre, Toronto, Ontario

Peking University First Hospital, Beijing, Not set

Peking University People s Hospital, Beijing, Not set

West China Hospital Si Chuan University, Chengdu, Not set

First affiliated Hospital of Zhejiang University, Hangzhou, Not set

Ruijin Hospital Shanghai Jiao Tong University, Shanghai, Not set

CHU de Limoges, Limoges Cedex, Not set

Centre hospitalier Lyon-Sud, Pierre Benite cedex, Not set

CHU De Poitiers, Poitiers, Not set

CHU Rangueil, Toulouse, Not set

Charite Campus Benjamin Franklin, Berlin, Not set

Universitatsklinikum Essen, Essen, Not set

Universitaetsklinikum Heidelberg Medizinische Klinik V, Heidelberg, Not set

Alexandra General Hospital of Athens, Athens, Not set

Università Degli Studi Di Napoli Federico Ii, Napoli, Not set

Fondazione IRCCS Policlinico San Matteo, Pavia, Not set

DIPARTIMENTO DI BIOTECNOLOGIE CELLULARI ED EMATOLOGIA - UNIVERSITà ''LA SAPIENZA'', Roma, Not set

University Medical Center Groningen, Groningen, Not set

Hospital Maastricht University Medical Center, Maastricht, Not set

UMC Utrecht, Utrecht, Not set

Hosp. Univ. Germans Trias I Pujol, Badalona, Not set

Hosp Univ Vall D Hebron, Barcelona, Not set

Hosp Clinic de Barcelona, Barcelona, Not set

Clinica Univ. de Navarra, Madrid, Not set

Clinica Univ. de Navarra, Pamplona, Not set

Hosp Clinico Univ de Salamanca, Salamanca, Not set

Leicester Royal Infirmary - Haematology, Leicester, Not set

University College Hospital, London, Not set

Conditions: Amyloidosis

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