Delirium Prevention With Ketamine in Ear, Nose, and Throat (ENT) Patients
Terminated
The goal of this prospective randomized double blinded placebo controlled study is to investigate if a single dose of ketamine in addition to standard anesthesia will reduce the risk of delirium in otolaryngeal cancer patients postoperatively. Ketamine's effect on post-operative pain and opioid use will be measured as well. Electroencephalogram (EEG) will be utilized during the surgical procedure to evaluate its potential as a possible predictive device for delirium.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/07/2021
Locations: Emory University Hospital Midtown, Atlanta, Georgia
Conditions: Otolaryngeal Cancer
Intranasal Esketamine to Maintain the Antidepressant Response to IV Racemic Ketamine
Completed
This study aims to assess the efficacy and safety of intranasal esketamine as maintenance antidepressant therapy in patients who have demonstrated clinical improvement with off-label intravenous racemic ketamine for treatment-resistant depression.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/19/2021
Locations: PsychAtlanta, Marietta, Georgia
Conditions: Treatment Resistant Depression
Safety and Efficacy of Repeated Doses of PMI-150 (Intranasal Ketamine) in Acute Post-operative Pain Following Orthopedic Surgery
Completed
The purpose of this research study is to evaluate the safety and analgesic efficacy of PMI-150 (intranasal ketamine) compared to placebo in patients with acute post-operative pain following orthopedic trauma, injury, or surgery.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
01/10/2012
Locations: Southeastern Center for Clinical Research, Atlanta, Georgia
Conditions: Pain, Postoperative