Pain Reduction With Intranasal Medications for Extremity Injuries
NCT02778880
Completed
This study compares the analgesic effect of intranasal sub-dissociative dosing of ketamine and intranasal fentanyl in children presenting to the Emergency Department with acute extremity injuries.
Gender:
ALL
Ages:
Between 8 years and 17 years
Trial Updated:
08/18/2020
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Pain, Traumatic Limb Injury
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Dexmedetomidine and Ketamine in MRI
NCT02652507
Completed
The purpose of this research study is to examine the effects of two commonly used anesthetic drugs, dexmedetomidine and ketamine, have on the shape and muscle tone of the upper airway in children, adolescents, and young adults. The results of this study will help in making the best decisions regarding the anesthesia medications used for sedation outside of the operating room.
Gender:
ALL
Ages:
Between 1 year and 18 years
Trial Updated:
07/23/2019
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Magnetic Resonance Imaging
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Study of Intranasal Ketamine for Social Impairment in Autism Spectrum Disorder
NCT02611921
Completed
The purpose of the study is to determine if intranasal ketamine shows initial evidence of safety, tolerability and efficacy for the treatment of social impairment in individuals with Autism Spectrum Disorder.
Gender:
ALL
Ages:
Between 12 years and 30 years
Trial Updated:
10/10/2018
Locations: Cincinnati Childrens Hospital Medical Center, Cincinnati, Ohio
Conditions: Autism Spectrum Disorder
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Ketamine Patient-Controlled Analgesia for Acute Pain
NCT02062879
Terminated
This study will compare ketamine and hydromorphone as alternative patient-controlled interventions for trauma-related pain. Patients receiving ketamine PCA are expected to require less total and breakthrough opioid and to have similar or improved objective pain scores. Patients receiving ketamine are also expected to have shorter duration of supplemental oxygen requirement, fewer episodes of oxygen desaturation, improved pulmonary toilet, lower use of antiemetics, and shorter times to first bowe... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/21/2017
Locations: University of Cincinnati Medical Center, Cincinnati, Ohio
Conditions: Acute Pain, Multiple Trauma, Fractures
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Emergency Ketamine Treatment of Suicidal Ideation
NCT02183272
Unknown
The objective of the current program of research will be to test whether intranasal ketamine treatment is more effective than placebo in reducing suicidal ideation in suicidal patients presenting for acute treatment in emergency department settings. Secondary objectives will test the effect of genotypic differences in the mu opioid receptor on efficacy of ketamine and the correlation of speech patterns and facial movement patterns with subjective reductions in suicidal ideation after ketamine tr... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/03/2016
Locations: University of Cincinnati, Cincinnati, Ohio
Conditions: Depression, Suicidal Ideation, Suicidal Impulses
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