ACL Repair and Multimodal Analgesia
Completed
This study will evaluate the effectiveness of an aggressive multimodal regimen versus standard multimodal for Anterior Cruciate Ligament (ACL) repair using hamstring graft for patients having surgery in our outpatient surgicenter.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
03/13/2020
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Pain
Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients
Completed
This study will evaluate the effectiveness of ketamine infusions in the management of acute pain resulting from broken ribs suffered following a blunt trauma. Half of patients will receive the institutional standard of care and a placebo infusion (no active medication). The other half of patients will receive the institutional standard of care and a ketamine infusion. All subjects and staff will be blinded as to whether they are receiving placebo or ketamine.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/27/2020
Locations: Froedtert Memorial Lutheran Hospital, Milwaukee, Wisconsin
Conditions: Wounds and Injuries, Rib Fractures
Ketamine in Colorectal Surgery
Withdrawn
This study will evaluate the effectiveness of ketamine infusions in the management of acute pain following open or laparoscopic colorectal surgery cases. Half of patients will receive the institutional standard of care and a placebo infusion (no active medication). The other half of patients will receive the institutional standard of care and a ketamine infusion. All subjects and staff will be blinded as to whether they are receiving placebo or ketamine.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/24/2017
Locations: Froedtert Memorial Lutheran Hospital, Milwaukee, Wisconsin
Conditions: Acute Pain, Pain, Postoperative, Colorectal Surgery
Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
Completed
RATIONALE: Baclofen-amitriptyline-ketamine (BAK) gel may lessen peripheral neuropathy caused by chemotherapy. It is not yet known whether BAK gel is more effective than a placebo in treating peripheral neuropathy caused by chemotherapy . PURPOSE: This randomized phase III trial is studying BAK gel to see how well it works compared with a placebo in treating peripheral neuropathy caused by chemotherapy in patients with cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2017
Locations: Franciscan Skemp Healthcare - La Crosse Campus, La Crosse, Wisconsin
Conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Lymphoproliferative Disorder, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Neurotoxicity, Pain, Unspecified Adult Solid Tumor, Protocol Specific
Topical Amitriptyline and Ketamine Cream in Treating Peripheral Neuropathy Caused by Chemotherapy in Cancer Patients
Completed
RATIONALE: Topical cream containing amitriptyline and ketamine may help relieve pain, numbness, tingling, and other symptoms of peripheral neuropathy. It is not yet known whether topical amitriptyline and ketamine cream is more effective than a placebo in treating peripheral neuropathy caused by chemotherapy. PURPOSE: This randomized phase III trial is studying the side effects and how well topical amitriptyline and ketamine cream work compared with a placebo in treating peripheral neuropathy c... Read More
Gender:
ALL
Ages:
Between 18 years and 120 years
Trial Updated:
10/13/2015
Locations: CCOP - Marshfield Clinic Research Foundation, Marshfield, Wisconsin
Conditions: Neurotoxicity, Pain, Peripheral Neuropathy, Unspecified Adult Solid Tumor, Protocol Specific