Physiologic Effects of PRMS & Testosterone in the Debilitated Elderly
NCT00018356
Completed
This study's primary objective is to determine the independent and combined effects of progressive resistance muscle strength training and testosterone on the development of sustainable improvements in physical function.
Gender:
MALE
Ages:
65 years and above
Trial Updated:
06/22/2011
Locations: Central Arkansas VHS Eugene J. Towbin Healthcare Ctr, Little Rock, No. Little Rock, Arkansas
Conditions: Muscle Weakness, Muscular Atrophy
Register for Updates
Effect of Dihydrotestosterone (DHT) on Prostate Tissue [Short Title: DHT-3]
NCT00490022
Completed
The purpose of this research study is to understand the effects of a male hormone normally made in the body called Dihydrotestosterone (DHT) on the prostate gland that is located under the bladder. The knowledge gained from this study may be used to help in the future to develop a safe male hormonal contraceptive to prevent pregnancy, in the safe treatment of low male hormone levels in men, and in the treatment and prevention of diseases of the prostate. The investigators will be giving DHT in... Read More
Gender:
MALE
Ages:
Between 35 years and 55 years
Trial Updated:
06/20/2011
Locations: University of Washington, Seattle, Washington
Conditions: Healthy
Register for Updates
A Pharmacokinetic (PK) Study to Compare the Absorption of Two Formulations of Transdermal Testosterone Spray and Intrinsa®
NCT01096329
Terminated
The purpose of this study is to determine if the absorption of the testosterone spray is the same as the Intrinsa® Patch.
Gender:
FEMALE
Ages:
Between 45 years and 65 years
Trial Updated:
06/06/2011
Locations: MDS Pharma Services, Tempe, Arizona
Conditions: Hypoactive Sexual Desire Disorder
Register for Updates
Multi-Site Randomized Clinical Study of Tinnitus Treatment Methods
NCT00235807
Completed
The purpose of this multi-site randomized clinical study was to assess treatment outcomes for three forms of tinnitus treatment: Tinnitus Retraining Therapy (TRT), Tinnitus Masking, and Tinnitus Education (TED). There were four study sites: VAMC Audiology Clinics at Bay Pines, FL; Portland, OR; Seattle, WA; and San Diego, CA. Thirty-six subjects (Veterans) were enrolled into treatment at each site - 12 into each treatment group. Each subject received 18 months of treatment. Treatment appointment... Read More
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
03/23/2011
Locations: VA Medical Center, Portland, Portland, Oregon
Conditions: Tinnitus
Register for Updates
Metabolic Effects of Steroids in Obese Men
NCT00983554
Unknown
Subjects will be randomized into 4 study groups: 1. Placebo; 2. Anastrazole and Testosterone; 3. Dutasteride and Testosterone; and 4. Testosterone only. A 2 step euglycemic clamp, body composition by dual X-ray absorptiometry scan, hormone and lipid assays will be performed to monitor metabolic effects of each treatment group. We hypothesize that increasing testosterone levels would increase lean mass, decrease fat mass and improve insulin sensitivity. We further hypothesize that improvements in... Read More
Gender:
MALE
Ages:
Between 24 years and 51 years
Trial Updated:
03/15/2011
Locations: University of California, San Diego, San Diego, California +1 locations
Conditions: Obesity, Insulin Resistance
Register for Updates
Effect of Lactose, Fructose, Sucrose, Whey Protein, and Soy Protein on Substrate Absorption and Oxidation: a Pilot Study
NCT00942513
Completed
Does the consumption of various combinations of mono and disaccharides (lactose, sucrose and fructose) and protein isolates (whey or soy) result in altered substrate absorption, substrate oxidation, and glucose regulation? This proposed research will provide data to determine the relative contribution of source of protein (whey vs soy) and carbohydrate (mono- and disaccharides) on the observed effects of dairy products on absorption, substrate oxidation and glucoregulation mechanisms that affect... Read More
Gender:
MALE
Ages:
Between 25 years and 65 years
Trial Updated:
02/08/2011
Locations: USDA-ARS, Beltsville Human Nutrition Research Center, Beltsville, Maryland
Conditions: Substrate Absorption, Substrate Oxidation, Glucose Regulation
Register for Updates
A Study of the Pharmacokinetics of Testosterone Metered Dose (MD)-Lotion Formulations
NCT00857961
Completed
Testosterone replacement treatment is the most effective way of treating hypogonadism in men. Acrux has a propriety testosterone replacement product, Testosterone MD-Lotion and this study will evaluate pharmacokinetics of testosterone MD-Lotion formulations.The study will also assess safety of the product.
Gender:
MALE
Ages:
Between 18 years and 70 years
Trial Updated:
01/06/2011
Locations: For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Tuscon, Arizona +3 locations
Conditions: Hypogonadism
Register for Updates
ORAL T-6: Oral Androgens in Man-6
NCT00663793
Completed
We propose a study to determine the single-dose pharmacokinetics of these two novel formulations of testosterone in normal men with experimentally induced hypogonadism.
Gender:
MALE
Ages:
Between 18 years and 50 years
Trial Updated:
12/27/2010
Locations: University of Washington, Seattle, Washington
Conditions: Contraception, Hypogonadism
Register for Updates
A Trial to Evaluate the Ongoing Skin Safety of Testosterone MD-Lotion Formulations
NCT00857454
Completed
Testosterone replacement treatment is the most effective way of treating hypogonadism in men. Acrux has a propriety testosterone replacement product, Testosterone MD-Lotion and this study will assess the occurrence of skin safety events for a further two months of continuous use of the Testosterone MD-Lotion® (cutaneous solution) after completion of the MTE08 (NCT00702650) trial.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
12/15/2010
Locations: For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Birmingham, Alabama +10 locations
Conditions: Hypogonadism
Register for Updates
AndroGel in Men With Major Depression and Incomplete Response to Antidepressant Treatment
NCT00304746
Completed
We hypothesize that AndroGel may offer some relief to subjects with low or borderline testosterone levels who suffer from depression and have failed to respond to a trial of a standard antidepressant. During this nine week, outpatient, double-blind study, male subjects between the ages of 30 and 65 years with treatment-refractory depression and low or borderline low testosterone levels will be treated with either AndroGel or placebo. Following this nine week, double-blind phase, eligible subjec... Read More
Gender:
MALE
Ages:
Between 30 years and 65 years
Trial Updated:
11/17/2010
Locations: McLean Hospital, Belmont, Massachusetts +1 locations
Conditions: Depressive Disorder, Major
Register for Updates
Effect of Testosterone Therapy in Men With Alzheimer's Disease and Low Testosterone
NCT00392912
Completed
Treatment with testosterone can improve performance on tests of spatial ability in men with low testosterone levels and Alzheimer's disease. Improved performance on these tests may mean an improved ability to get around in one's environment without getting lost or injured. This could have a positive impact on both patients and those who care for them. We will investigate what areas of the brain are involved in these improvements in spatial ability. This will be done using a PET scan, which creat... Read More
Gender:
MALE
Ages:
55 years and above
Trial Updated:
08/18/2010
Locations: Michael E. DeBakey VA Medical Center, Houston, Texas
Conditions: Alzheimer's Disease, Hypogonadism
Register for Updates
The Role of 5-alpha Reductase in Mediating Testosterone Actions
NCT00493987
Completed
In normal men, the male hormone testosterone affects a number of things in the body including muscle function and sexual function. An enzyme in the body called 5-alpha reductase converts testosterone into another form called dihydrotestosterone (DHT) which has slightly different effects. The purpose of this study is to find out how different amounts of the two different forms of testosterone affect muscle function and sexual function in healthy young men like you. This will be done by giving the... Read More
Gender:
MALE
Ages:
Between 18 years and 50 years
Trial Updated:
05/12/2010
Locations: Boston University Medical Center, Boston, Massachusetts
Conditions: Healthy
Register for Updates