Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone (HOP 5) Testicular Aspiration Addendum
NCT00156650
Completed
This study is being offered to all participants of the ACY-5 study as an optional addition to the male contraceptive study in which they participated. Participation is voluntary. The purpose of this added procedure (Testicular Aspiration-HOP 3) is to determine the amount of testosterone (male hormone) in the testes of men who are on a male contraceptive regimen.
Gender:
MALE
Ages:
Between 18 years and 55 years
Trial Updated:
09/18/2008
Locations: University of Washington, Seattle, Washington
Conditions: Contraception
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Oral Androgens in Man-3 (ORAL T-3) Pharmacokinetics of Oral Testosterone
NCT00161421
Completed
The purpose of this study is to test the how the body absorbs and processes new forms of oral testosterone. Information gained during the study may help develop better forms of testosterone therapy in the future. We will be administering three drugs. Dutasteride is FDA approved to treat prostate enlargement. Lupron is approved for treatment of prostate cancer. Testosterone is approved for treatment of testicular insufficiency. They are being used in this study for "off-label" research purposes.... Read More
Gender:
MALE
Ages:
Between 18 years and 50 years
Trial Updated:
09/18/2008
Locations: University of Washington, Seattle, Washington
Conditions: Contraception, Hypogonadism
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Male Hormonal Contraceptive Development-ACY-5
NCT00161447
Completed
The purpose of this research study is to help in the development of male contraception (birth control).
Gender:
MALE
Ages:
Between 18 years and 55 years
Trial Updated:
09/18/2008
Locations: University of Washington, Seattle, Washington
Conditions: Contraception
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The Effects of Testosterone on Prostate Tissue (ACYP-1)
NCT00161486
Completed
The purpose of this research study is to understand the effects of testosterone on the prostate. This knowledge will be used to help in the development of a safe male hormonal contraceptive and may impact the development of androgen replacement therapy in older men.
Gender:
MALE
Ages:
Between 35 years and 55 years
Trial Updated:
09/18/2008
Locations: University of Washington, Seattle, Washington
Conditions: Hypogonadism, Contraception
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Oral Androgens in Man-4: (Short Title: Oral T-4)
NCT00399165
Completed
The protocol was designed to address the hypothesis that oral testosterone enanthate plus dutasteride can suppress the secretion of LH and FSH after four weeks of administration. In addition, we will compare the gonadotropin suppression mediated by a dose of testosterone enanthate (400 mg twice daily) that would be expected to maintain the serum testosterone in the normal range throughout the day, with the same dose (800 mg once daily) administered once daily. This larger once-daily dose is expe... Read More
Gender:
MALE
Ages:
Between 18 years and 55 years
Trial Updated:
09/18/2008
Locations: University of Washington, Seattle, Washington
Conditions: Contraception
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Comparison of Estrogen and Methyltestosterone Combination Treatments for Postmenopausal Hot Flushes
NCT00160342
Completed
This is a research study to evaluate the effectiveness, safety and side effects of several dose levels of esterified estrogens (EE) and methyltestosterone (MT) given individually and in combination compared to a placebo (a tablet with no active drug in it) as a possible treatment for vasomotor symptoms (such as hot flushes and flushing) of menopause. EE and testosterone are two hormones which are typically deficient in menopausal women
Gender:
FEMALE
Ages:
Between 45 years and 65 years
Trial Updated:
08/14/2008
Locations: Site 37, Montgomery, Alabama +124 locations
Conditions: Hot Flushes, Menopause, Postmenopause
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Pharmacokinetics of Testosterone Lotion in the Treatment of Hypogonadal Males
NCT00372008
Completed
Testosterone replacement treatment is the most effective way of treating hypogonadism in men. Acrux has a proprietry testosterone replacement product - Testosterone-MD Lotion, and this study will evaluate the efficacy and safety of this product.
Gender:
MALE
Ages:
Between 18 years and 70 years
Trial Updated:
06/18/2008
Locations: Birmingham, Birmingham, Alabama +6 locations
Conditions: Hypogonadism
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The Efficacy of ESTRATEST® Tablets in Relieving Menopausal Symptoms in Estrogenized, Non-Hysterectomized Postmenopausal Women
NCT00141544
Terminated
To determine whether treatment with ESTRATEST® Tablets is superior to treatment with esterified estrogens tablets
Gender:
FEMALE
Ages:
Between 35 years and 65 years
Trial Updated:
04/10/2008
Locations: Site 66, Huntsville, Alabama +77 locations
Conditions: Menopause
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The Efficacy of ESTRATEST® Tablets in Relieving Menopausal Symptoms in Estrogenized, Hysterectomized Postmenopausal Women
NCT00141557
Terminated
To determine whether treatment with ESTRATEST® Tablets is superior to treatment with esterified estrogens tablets
Gender:
FEMALE
Ages:
Between 35 years and 65 years
Trial Updated:
04/10/2008
Locations: Site 66, Huntsville, Alabama +77 locations
Conditions: Menopause
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Pharmacokinetic Evaluation of Testosterone Gel (1%)
NCT00193700
Completed
Measure and evaluate the level of testosterone in blood, and determine the safety and tolerability following daily applications of testosterone gel. Subjects who complete this trial may participate in the extension part (UMD-01-080E).
Gender:
MALE
Ages:
Between 13 years and 17 years
Trial Updated:
12/23/2006
Locations: Site 208, Birmingham, Alabama +8 locations
Conditions: Primary or Secondary Hypogonadism, Constitutional Delay in Growth and Puberty (CDGP)
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The Effect of 5-Alpha Reductase on Testosterone in Men
NCT00070733
Unknown
The enzyme 5-alpha reductase is present in small amounts in muscle and converts testosterone to dihydrotestosterone (DHT). Testosterone affects lean body tissue, muscle size, muscle strength, and sexual function in men. This study will evaluate how 5-alpha reductase influences the effects of testosterone in young healthy men.
Gender:
MALE
Ages:
Between 21 years and 40 years
Trial Updated:
11/04/2005
Locations: Charles R. Drew University, Los Angeles, California
Conditions: Sex Disorders
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Randomized Study of Testosterone and Progressive Resistance Exercise in Men With Burn Injury
NCT00006129
Unknown
OBJECTIVES: I. Determine whether testosterone normalization ameliorates muscle protein hypercatabolism by increasing net protein synthesis in men with burn injury. II. Determine whether the effectiveness of testosterone is enhanced by stimulation of inward amino acid transport as a consequence of hyperaminoacidemia in these men. III. Determine whether testosterone normalization during hospitalization minimizes the need for rehabilitation by increasing net protein synthesis and preserving skele... Read More
Gender:
MALE
Ages:
Between 18 years and 50 years
Trial Updated:
06/23/2005
Locations: University of Texas Medical Branch, Galveston, Texas
Conditions: Burns
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