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Testosterone Replacement Therapy (TRT) Treatment Options
A collection of 324 research studies where Testosterone Replacement Therapy (TRT) is the interventional treatment. These studies are located in the United States . Testosterone Replacement Therapy (TRT) is used for conditions such as .
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A Study of the Safety and Tolerability of LPCN 1144 in Subjects Who Completed the LPCN 1144-18-002 Trial
Completed
This is an open-label extension to Study LPCN 1144-18-002. The study is aimed at evaluating the safety and tolerability of LPCN 1144 in adult men with NASH.
Gender:
MALE
Ages:
Between 18 years and 80 years
Trial Updated:
06/25/2024
Locations: Clinical Trials Research, Roseville, California +9 locations
Conditions: NASH - Nonalcoholic Steatohepatitis
Comparing Subcutaneous Testosterone to Intramuscular Testosterone in Gender Affirming Care of Transgender Male Adolescents
Completed
The trial studies the efficacy of subcutaneous (SQ) testosterone compared to intramuscular (IM) testosterone therapy during the first 6 months of pubertal induction in transgender male adolescents. Describes rate of adverse effects, masculinizing effects and quality of life while receiving testosterone. Evaluates clinic utilization required for testosterone therapy.
Gender:
FEMALE
Ages:
Between 14 years and 19 years
Trial Updated:
04/01/2024
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Health Services for Transgender Persons, Transgender Persons
COMbination of Bipolar Androgen Therapy and Nivolumab
Completed
Single arm, multicenter, open-label Phase II study of the effects of parenteral testosterone in combination with nivolumab in men with metastatic castration-resistant prostate cancer who previously progressed on at least one novel androgen-receptor targeted therapy (i.e. Abiraterone acetate, Enzalutamide). Up to one taxane agent is permitted.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
02/15/2024
Locations: UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California +2 locations
A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men
Completed
This is a double-blinded and placebo-controlled study of topical testosterone replacement therapy (TRT) in symptomatic hypogonadal men with pre-existing cardiovascular disease (CVD) or increased risk for CVD.
Gender:
MALE
Ages:
Between 45 years and 80 years
Trial Updated:
02/14/2024
Locations: Wright Clinical Research, LLC /ID# 210864, Alabaster, Alabama +383 locations
Conditions: Hypogonadism, Cardiovascular Diseases
Sex-Mismatched Allogeneic Bone Marrow Transplantation for Men With Metastatic Castration-Resistant Prostate Cancer
Terminated
Men with progressive metastatic Castration-Resistant Prostate Cancer post first-line treatment with either androgen deprivation therapy alone or androgen deprivation therapy plus docetaxel who have an identified related female donor (mother sister, daughter, second degree relative such as granddaughter or niece) will undergo bone marrow transplantation followed by post-transplant Cytoxan (PT/Cy) and testosterone.
Gender:
MALE
Ages:
Between 18 years and 75 years
Trial Updated:
02/09/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Prostate Cancer
Effect of Androgel on Atherogenesis in Type 2 Diabetic Males With Hypogonadotrophic Hypogonadism
Terminated
The purpose of this study is to examine the effects of testosterone deficiency in men with diabetes on atherogenesis, inflammation, cardiovascular Risk factors And adiposity .
Gender:
MALE
Ages:
Between 31 years and 60 years
Trial Updated:
02/03/2024
Locations: Diabetes Endocrinology Research Center of WNY, Buffalo, New York
Conditions: Type 2 Diabetic Male With Hypogonadotrophic Hypogonadism
Effect of Transgender Therapy on Muscle, Fat and Tissue Receptors
Terminated
The purpose of this research is to find out if hormone therapy in transgender subjects' changes hormone receptors in blood, muscle and fat; fat production; muscle production; and inflammation processes.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
01/04/2024
Locations: Saint Louis Univeristy, Saint Louis, Missouri
Conditions: Gender Incongruence, Transgenderism
Mechanisms of Hypertension in Women With Polycystic Ovary Syndrome
Terminated
Women with androgen excess polycystic ovary syndrome (AE-PCOS) leads to hypertension.
Gender:
FEMALE
Ages:
Between 18 years and 35 years
Trial Updated:
01/04/2024
Locations: The John B Pierce Laboratory, New Haven, Connecticut
Conditions: Polycystic Ovary Syndrome, Hypertension
The Efficacy, Safety and Tolerability of Oral LPCN 1144 in Subjects With Nonalcoholic Steatohepatitis
Completed
This is a Phase 2, randomized, double-blind, placebo controlled, three arm study in adult men with biopsy confirmed NASH. The study is aimed at evaluating efficacy and tolerability of LPCN 1144 in adult men with NASH.
Gender:
MALE
Ages:
Between 18 years and 80 years
Trial Updated:
12/12/2023
Locations: TriWest Research Associates, LLC, El Cajon, California +18 locations
Conditions: Nonalcoholic Steatohepatitis (NASH)
A Randomized Study of Testosterone Replacement in Patients With Low Risk Hormone Refractory Prostate Cancer
Completed
The purpose of this study is to see how safe Androderm® (the study drug) is at three different doses in subjects with early hormone refractory prostate cancer. In addition, information about hormonal levels and the effects of testosterone on quality of life including sexual functioning and muscle strength will be collected.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: University of Chicago, Chicago, Illinois
Conditions: Prostate Cancer
Patient Satisfaction After Switching to Oral Testosterone Undecanoate
Completed
The purpose of this research study is to evaluate patient satisfaction with an oral testosterone agent, Jatenzo, compared to other forms of testosterone therapy.
Gender:
MALE
Ages:
Between 18 years and 65 years
Trial Updated:
11/21/2023
Locations: University of Miami, Miami, Florida
Conditions: Testosterone Deficiency
A Comparison of Side Effects in Hypogonadal Men Treated With Natesto Versus Testosterone Injections
Completed
The purpose of this study is to evaluate changes in vascular parameters and the prevalence of side effects in subjects receiving 1 cc (200mg) every 2 weeks intramuscular (IM) of Testosterone Cypionate versus subjects receiving 11mg three times daily (TID) Natesto to participant with clinical hypogonadism.
Gender:
MALE
Ages:
Between 18 years and 75 years
Trial Updated:
11/21/2023
Locations: University of Miami Miller School of Medicine, Miami, Florida
Conditions: Hypogonadism, Male
73 - 84 of 324