United Kingdom based Breast Cancer Clinical Trials & Research Studies Near You (Updated 8/25)

Improving Muslim Women's Uptake of Cancer Screening (IMCAN)

NCT06106165

Recruiting

The goal of this non-randomised trial is to test how a workshop that includes religiously-tailored messages can help increase the uptake of breast, colorectal and cervical cancer screening among Muslim women in North East England and Scotland. The results of this trial will inform the development of a full-scale randomised-controlled trial. Participants in this study will be asked to take part in a two-hour workshop, deliver either online or in-person.

Gender:

FEMALE

Ages:

Between 25 years and 74 years

Trial Updated:

04/11/2025

Locations: University of Glasgow, Glasgow, Scotland +1 locations

Conditions: Breast Cancer, Bowel Cancer, Cervical Cancer

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A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours

NCT04969835

Recruiting

This is a first-in-human (FIH), Phase 1 open-label, multicentre dose escalation study investigating AVA6000 monotherapy administered intravenously in patients with locally advanced (unresectable) or metastatic solid tumours that are likely to be FAP positive. The study consists of an initial Phase 1a dose escalation portion and a subsequent Phase 1b dose expansion portion upon completion of the dose escalation portion.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/10/2025

Locations: Memorial Sloan Kettering Cancer Center, New York, New York +8 locations

Conditions: Breast Cancer, Soft Tissue Sarcoma, Salivary Gland Tumor, Urothelial Carcinoma, Ovarian Carcinoma

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Chemotherapy Induced Cognitive Impairment

NCT05740787

Recruiting

Chemotherapy is toxic and challenges everyone differently. Most chemotherapy side-effects are known and well documented. However, the phenomenon of "chemo fog" also known as "chemobrain" has not been fully investigated and is often based on comments of breast cancer patients attending outpatient clinics during and after their chemotherapy. Changes in thinking ability like lack of concentration, loss of memory and the inability to hold a thought or even a conversation has a significant impact on... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/08/2025

Locations: NHS Grampian, Aberdeen, Not set

Conditions: Breast Cancer

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Biological Matrices Versus Synthetic Meshes

NCT05449691

Recruiting

In this feasibility study, 60 women undergoing reconstruction will be randomly allocated to receive biological or synthetic mesh and followed for 6 months. The findings will tell us if patients and surgeons are comfortable with not being able to choose which mesh is used for the operation. In the larger surgical study, the investigators plan to measure patients' satisfaction with the reconstruction, patients' quality of life, complications from the operation and costs over 5 years.

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

02/03/2025

Locations: University Hospitals of Derby and Burton NHS Foundation Trust, Derby, Not set +4 locations

Conditions: Breast Cancer

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The EMBRACE Study The EMBRACE Study

NCT04467411

Recruiting

Cardiomyopathy is a condition that affects the heart muscle, whereby it becomes enlarged, thick or rigid. When the heart muscle becomes involved, it affects the pumping action of the heart. This condition can affect as many as 10% of all patients after undergoing anthracycline cancer drug therapy and unfortunately carries the worst prognosis of all cardiomyopathies. To date, there is no effective intervention that will prevent a patient from developing this condition. The research conducted will... Read More

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

12/18/2024

Locations: Cardiovascular Research Facility, Aberdeen, Aberdeenshire

Conditions: Breast Cancer

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Breast Cancer Evolution During Neoadjuvant Systemic Therapy

NCT06681064

Recruiting

BELIEVE is a translational research study that aims to collect samples of breast cancer tissue and blood from individuals undergoing breast cancer treatment (such as chemotherapy, targeted therapy and immunotherapy) before surgery. In certain cases, MRI scans and stool samples will also be obtained before and during treatment. The samples collected from this study will be used for molecular and genetic research to understand why some cancers respond very well to anticancer treatments, and some d... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

11/07/2024

Locations: Royal Marsden NHS Foundation Trust, London, Not set

Conditions: Breast Cancer, Triple Negative Breast Cancer, ER+ Breast Cancer, HER2+ Breast Cancer

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Axillary Management in Breast Cancer Patients with Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy

NCT04109079

Recruiting

The aim of this study is to assess whether, omitting further axillary treatment (ALND and ART) for patients with early stage breast cancer and axillary nodal metastases on needle biopsy, who after NACT have no residual cancer in the lymph nodes on sentinel node biopsy, is non-inferior to axillary treatment in terms of disease free survival (DFS) and results in reduced risk of lymphoedema at 5 years.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

10/22/2024

Locations: Galway University Hospitals, Galway, Not set +87 locations

Galway University Hospitals, Galway, Not set

Airedale NHS Foundation Trust, Keighley, Bd20 6td

North Cumbria Integrated Care NHS Foundation Trust, Carlisle, Ca2 7hy

Frimley Health NHS Foundation Trust, Camberley, Gu16 7uj

NHS Highland, Inverness, Iv2 3uj

James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, Nr31 6la

Royal Berkshire NHS Foundation Trust, Reading, Rg1 5an

East Cheshire NHS Trust, Macclesfield, Sk10 3bl.

The Shrewsbury and Telford Hospitals NHS Trust, Shrewsbury, Sy3 8xq

NHS Grampian, Aberdeen, Not set

Ashford and St Peter's Hospitals NHS Foundation Trust, Ashford, Not set

Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-under-Lyne, Not set

NHS Ayrshire and Arran, Ayr, Not set

Belfast Health and Social Care Trust, Belfast, Not set

University Hospitals Birmingham NHS Foundation Trust, Birmingham, Not set

Sandwell and West Birmingham NHS Trust, Birmingham, Not set

Bolton NHS Foundation Trust, Bolton, Not set

Bradford Teaching Hospitals NHS Foundation Trust, Bradford, Not set

University Hospitals Sussex NHS Foundation Trust, Brighton, Not set

North Bristol NHS Trust, Bristol, Not set

East Lancashire Hospitals NHS Trust, Burnley, Not set

Cambridge University Hospitals NHS Foundation Trust, Cambridge, Not set

Gloucestershire General Hospitals NHS Foundation Trust, Cheltenham, Not set

Countess of Chester Hospital NHS Trust, Chester, Not set

Mid Cheshire NHS Foundation Trust, Crewe, Not set

County Durham and Darlington NHS Foundation Trust, Darlington, Not set

University Hospitals of Derby and Burton NHS Foundation Trust, Derby, Not set

Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust, Doncaster, Not set

The Dudley Group NHS Foundation Trust, Dudley, Not set

NHS Dumfries and Galloway, Dumfries, Not set

NHS Fife, Dunfermline, Not set

NHS Lanarkshire, East Kilbride, Not set

NHS Lothian, Edinburgh, Not set

Royal Devon and Exeter NHS Foundation Trust, Exeter, Not set

Gateshead Health NHS Foundation Trust, Gateshead, Not set

Harrogate and District NHS Foundation Trust, Harrogate, Not set

Wye Valley NHS Trust, Hereford, Not set

Buckinghamshire Healthcare NHS Trust, High Wycombe, Not set

Calderdale and Huddersfield NHS Foundation Trust, Huddersfield, Not set

Hull University Teaching Hospitals NHS Trust, Hull, Not set

East Suffolk and North Essex NHS Foundation Trust, Ipswich, Not set

Chelsea and Westminster Hospital NHS Foundation Trust, Isleworth, Not set

University Hospitals of Morecambe Bay NHS Foundation Trust, Lancaster, Not set

NHS Forth Valley, Larbert, Not set

Leeds Teaching Hospitals NHS Trust, Leeds, Not set

University Hospitals of Leicester NHS Trust, Leicester, Not set

United Lincolnshire Hospitals NHS Trust, Lincoln, Not set

Hywel Dda University Health Board, Llanelli, Not set

North Middlesex University Hospital NHS Trust, London, Not set

Whittington Health NHS Trust, London, Not set

University College London Hospitals NHS Foundation Trust, London, Not set

Royal Free London NHS Foundation Trust, London, Not set

King's College Hospital NHS Foundation Trust, London, Not set

The Royal Marsden NHS Foundation Trust, London, Not set

Imperial College Healthcare NHS Trust, London, Not set

Bedfordshire Hospitals NHS Foundation Trust, Luton, Not set

Manchester University NHS Foundation Trust, Manchester, Not set

NHS Borders, Melrose, Not set

South Tees Hospitals NHS Foundation Trust, Middlesbrough, Not set

Milton Keynes University Hospital NHS Trust, Milton Keynes, Not set

Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, Not set

Northumbria Healthcare NHS Foundation Trust, North Shields, Not set

Oxford University Hospitals NHS Foundation Trust, Oxford, Not set

NHS Greater Glasgow and Clyde, Paisley, Not set

University Hospitals Plymouth NHS Trust, Plymouth, Not set

Portsmouth Hospitals University NHS Trust, Portsmouth, Not set

St Helens and Knowsley Teaching Hospitals NHS Trust, Prescot, Not set

Lancashire Teaching Hospitals NHS Foundation Trust, Preston, Not set

Surrey & Sussex Healthcare NHS Trust, Redhill, Not set

The Rotherham NHS Foundation Trust, Rotherham, Not set

Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, Not set

West Hertfordshire Hospitals NHS Trust, St Albans, Not set

East and North Hertfordshire NHS Foundation Trust, Stevenage, Not set

North Tees and Hartlepool NHS Foundation Trust, Stockton-on-Tees, Not set

University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, Not set

Swansea Bay University Health Board, Swansea, Not set

Somerset NHS Foundation Trust, Taunton, Not set

Croydon Health Services NHS Trust, Thornton Heath, Not set

Royal Cornwall Hospitals NHS Trust, Truro, Not set

Mid Yorkshire Hospitals NHS Trust, Wakefield, Not set

Mid and South Essex NHS Foundation Trust, Westcliff-on-Sea, Not set

Wrightington, Wigan and Leigh Teaching Hospitals NHS Foundation Trust, Wigan, Not set

Clatterbridge Cancer Centre NHS Foundation Trust, Wirral, Not set

Wirral University Teaching Hospital NHS Foundation Trust, Wirral, Not set

The Royal Wolverhampton NHS Trust, Wolverhampton, Not set

Worcestershire Acute Hospitals NHS Trust, Worcester, Not set

Yeovil District Hospital NHS Trust, Yeovil, Not set

York and Scarborough Teaching Hospitals NHS Foundation Trust, York, Not set

Conditions: Breast Cancer, Sentinel Lymph Node, Neoplasm, Breast

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Magseed Pro(R)/ Sentimag(R) Gen3

NCT05142787

Recruiting

The purpose of this study is to provide prospective evidence that the Magseed Pro® marker /Sentimag® Gen3 system is safe and effective for marking A. suspicious/biopsy-proven positive axillary lymph nodes; and B. soft tissue lesions including cancer and pre-cancerous change in the breast

Gender:

ALL

Ages:

18 years and above

Trial Updated:

09/10/2024

Locations: Marienhospital Bottrop GmbH, Bottrop, Not set +5 locations

Conditions: Breast Cancer

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HERPET- A Novel PET Imaging Study of HER2 in Breast Cancer

NCT03827317

Recruiting

This mechanistic study will be the first study to assess the efficacy of \[18F\]GE-226 to target HER2 expression in patients with metastatic breast cancer. The study will establish the pharmacokinetics of \[18F\]GE-226 and the optimum time-point for performing static scans in this patient population.

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

08/23/2024

Locations: Imperial College Healthcare NHS Trust, London, Not set

Conditions: Breast Cancer

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Laser Speckle Imaging During Breast Reconstruction

NCT06523452

Recruiting

Around 3500 women a year have surgery to reconstruct a breast/s after cancer. Breast reconstruction can have a positive impact on their lives, but unfortunately 3 or 4 in 10 women have problems with healing after their operation. This is distressing and often leads to more medical care or surgery. These problems are often caused by poor blood flow to the skin and deeper tissues used to reconstruct the breast. The investigators have developed a new device that does not touch the skin and provides... Read More

Around 3500 women a year have surgery to reconstruct a breast/s after cancer. Breast reconstruction can have a positive impact on their lives, but unfortunately 3 or 4 in 10 women have problems with healing after their operation. This is distressing and often leads to more medical care or surgery. These problems are often caused by poor blood flow to the skin and deeper tissues used to reconstruct the breast. The investigators have developed a new device that does not touch the skin and provides immediate, continuous images of skin blood flow (the flow that surgeons cannot see). To test this device the investigators took images of blood flow during breast reconstruction surgery. The investigators found that imaging was good at showing where skin blood flow was poor and led to problems with healing and where flow was good and there were fewer problems after surgery (from minor problems, e.g. delayed healing; to major problems, e.g. loss of new breast). The investigators think this device can help surgeons choose healthy skin during breast reconstruction and so help more patients to heal without surgical problems. The investigators need to test the new imaging device in a large clinical trial to find out how effective it is at improving healing for women after breast reconstruction. Before this, the investigators need to find out if such a trial is possible and acceptable to patients, theatre staff and surgeons. The investigators will recruit 60 women who are having breast surgery and will randomly choose 30 to have surgery without blood flow imaging and 30 to have surgery with blood flow imaging. The investigators will follow up the women whilst in hospital and for the following 6 months to record any problems. In particular the investigators need to find out how many patients will volunteer for the study and the study can collect all the information needed during the 6 months after surgery. The results from this study will be used to plan a much larger clinical trial that will test whether blood flow imaging is effective, improves patient recovery after surgery and provides good value for money for the NHS. Read Less

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

07/23/2024

Locations: Royal Devon University Healthcare NHS Foundation Trust, Exeter, Devon

Conditions: Breast Cancer

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An Investigation Into Dielectric Assessment of Permittivity and Conductivity in Human Using a Novel Electrical Capacitance Tomography Scanner

NCT06264934

Recruiting

The goal of this observational study is to investigate the ability of a the Z-scanner to identify and differentiate cancer and benign lesions from healthy breast tissue based on permittivity. The main questions it aims to answer are: 1. Determine the permittivity values of the Z-scanner associated with healthy, benign, and malignant tissue in human breasts. 2. Determine the repeatability, reproducibility, inter-and intra-operator variability of the Z-scanner.

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

06/05/2024

Locations: Imperial College Healthcare NHS Trust, London, Not set

Conditions: Breast Cancer, Benign Breast Disease

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Oncologic, Cosmetic and Patient Reported Outcomes in Value-Based Breast Surgery (OnCoPRO Value)

NCT06401304

Recruiting

The study aspires to provide outcomes on surgery, quality of life and time-to-event outcomes following the development and validation of a standardised surgical assessment tool in a shared decision-making framework for patients with pre-invasive or invasive breast cancer with breast conservation.

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

05/02/2024

Locations: Westmead Breast Cancer Institute, Sydney, Not set +2 locations

Conditions: Breast Cancer, Breast Carcinoma in Situ, Breast Cancer Invasive, Breast Asymmetry

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Breast Cancer Clinical Trials in United Kingdom

Match to Clinical Trials