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Breast Neoplasms Clinical Trials in United Kingdom
A listing of 9 Breast Neoplasms clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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There are currently 9 active clinical trials seeking participants for Breast Neoplasms research studies. The states with the highest number of trials for Breast Neoplasms participants are .
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
Recruiting
The purpose of this study is to compare sacituzumab tirumotecan as a single agent, and in combination with pembrolizumab, versus Treatment of Physician's Choice (TPC) in participants with hormone receptor positive/human epidermal growth factor receptor-2 negative (HR+/HER2-) unresectable locally advanced, or metastatic, breast cancer.
The primary hypotheses are that sacituzumab tirumotecan as a single agent and sacituzumab tirumotecan plus pembrolizumab are superior to TPC with respect to progr... Read More
The purpose of this study is to compare sacituzumab tirumotecan as a single agent, and in combination with pembrolizumab, versus Treatment of Physician's Choice (TPC) in participants with hormone receptor positive/human epidermal growth factor receptor-2 negative (HR+/HER2-) unresectable locally advanced, or metastatic, breast cancer.
The primary hypotheses are that sacituzumab tirumotecan as a single agent and sacituzumab tirumotecan plus pembrolizumab are superior to TPC with respect to progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) by blinded independent central review (BICR) in all participants. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Ironwood Cancer & Research Centers ( Site 0066), Chandler, Arizona +241 locations
Ironwood Cancer & Research Centers ( Site 0066), Chandler, Arizona
Banner MD Anderson Cancer Center-Oncology ( Site 0004), Gilbert, Arizona
Providence Medical Foundation-Oncology ( Site 0020), Fullerton, California
Moores Cancer Center ( Site 0059), La Jolla, California
Cancer and Blood Specialty Clinic ( Site 0001), Los Alamitos, California
University of Colorado Anschutz Medical Campus ( Site 0061), Aurora, Colorado
UCHealth Cherry Creek Medical Center ( Site 0094), Denver, Colorado
University of Colorado Health - Highlands Ranch Hospital ( Site 0095), Highlands Ranch, Colorado
Yale Cancer Center ( Site 0060), New Haven, Connecticut
Stamford Hospital ( Site 0049), Stamford, Connecticut
AdventHealth Altamonte Springs ( Site 0021), Altamonte Springs, Florida
University of Florida College of Medicine ( Site 0063), Gainesville, Florida
Orlando Health Cancer Institute ( Site 0011), Orlando, Florida
Archbold Memorial Hospital-Lewis Hall Singletary Oncology Center ( Site 0032), Thomasville, Georgia
University of Chicago Medical Center ( Site 0067), Chicago, Illinois
Saint Elizabeth Medical Center Edgewood-Cancer Care Center ( Site 0053), Edgewood, Kentucky
Mary Bird Perkins Cancer Center-Breast & GYN Pavilion ( Site 0042), Baton Rouge, Louisiana
Greenebaum Comprehensive Cancer Center ( Site 0036), Baltimore, Maryland
Mercy Medical Center - Baltimore-Medical Oncology and Hematology ( Site 0028), Baltimore, Maryland
Holy Cross Hospital ( Site 0073), Silver Spring, Maryland
Dana-Farber Cancer Institute-Breast Oncology Center ( Site 0037), Boston, Massachusetts
Henry Ford Health ( Site 0002), Detroit, Michigan
Saint Luke's Cancer Institute ( Site 0027), Kansas City, Missouri
Washington University School of Medicine ( Site 0076), Saint Louis, Missouri
Laura and Isaac Perlmutter Cancer Center-Hematology and Oncology ( Site 0068), New York, New York
Hematology Oncology Associates of Rockland ( Site 0054), Nyack, New York
Stony Brook University-Cancer Center ( Site 0034), Stony Brook, New York
Levine Cancer Institute ( Site 0014), Charlotte, North Carolina
Zangmeister Cancer Center ( Site 7000), Columbus, Ohio
Providence Portland Medical Center ( Site 0044), Portland, Oregon
Providence St. Vincent Medical Center ( Site 0081), Portland, Oregon
Thomas Jefferson University - Clinical Research Institute ( Site 0056), Philadelphia, Pennsylvania
Texas Oncology-Dallas Presbyterian Hospital ( Site 8000), Dallas, Texas
The Center for Cancer and Blood Disorders ( Site 0041), Fort Worth, Texas
Texas Oncology - San Antonio ( Site 8002), San Antonio, Texas
The University of Texas Health Science Center at Tyler dba UT Health East Texas HOPE Cancer Center ( Site 0057), Tyler, Texas
Inova Schar Cancer Institute ( Site 0025), Fairfax, Virginia
Bon Secours St. Francis Medical Center-Oncology Research ( Site 0015), Midlothian, Virginia
VCU Health Adult Outpatient Pavillion ( Site 0070), Richmond, Virginia
Oncology and Hematology Associates of Southwest Virginia (BRCC) ( Site 8001), Roanoke, Virginia
University Hospital and UW Health Clinics-Carbone Cancer Center ( Site 0040), Madison, Wisconsin
Instituto Alexander Fleming-Alexander Fleming ( Site 0382), Ciudad Autónoma de Buenos Aires, Caba
Fundacion Estudios Clinicos-Oncology ( Site 0384), Rosario, Santa Fe
Hospital Aleman-Oncology ( Site 0386), Buenos Aires, Not set
Centro de Educación Médica e Investigaciones clínicas "Dr. Norberto Quirno" (CEMIC) ( Site 0383), Buenos Aires, Not set
Hospital Italiano de Córdoba ( Site 0385), Cordoba, Not set
Fundación CORI para la Investigación y Prevención del Cáncer ( Site 0387), La Rioja, Not set
Macquarie University-MQ Health Clinical Trials Unit ( Site 2002), Macquarie University, New South Wales
Westmead Hospital ( Site 2000), Westmead, New South Wales
Frankston Hospital-Oncology and Haematology ( Site 2003), Frankston, Victoria
Fiona Stanley Hospital-Medical Oncology ( Site 2004), Murdoch, Western Australia
Institut Jules Bordet-Medicine Oncology ( Site 1104), Anderlecht, Bruxelles-Capitale, Region De
Cliniques universitaires Saint-Luc-Medical Oncology ( Site 1103), Brussels, Bruxelles-Capitale, Region De
Jessa Ziekenhuis-Limburgs Oncologisch Centrum ( Site 1105), Hasselt, Limburg
AZ Maria Middelares-IKG ( Site 1106), Gent, Oost-Vlaanderen
Université Catholique de Louvain-Namur - Centre Hospitalier -Oncology ( Site 1107), Namur, Not set
Oncoclínica Oncologistas Associados-Clinical Research ( Site 0407), Teresina, Piaui
Hospital Moinhos de Vento ( Site 0403), Porto Alegre, Rio Grande Do Sul
Hospital do Câncer Mãe de Deus ( Site 0404), Porto Alegre, Rio Grande Do Sul
Instituto de Oncologia Saint Gallen ( Site 0412), Santa Cruz do Sul, Rio Grande Do Sul
Instituto do Câncer Brasil - Unidade Taubaté ( Site 0408), Taubaté, Sao Paulo
IBCC - Núcleo de Pesquisa e Ensino ( Site 0401), Sao Paulo, Not set
BC Cancer Surrey ( Site 0315), Surrey, British Columbia
Southlake Regional Health Centre ( Site 0311), Newmarket, Ontario
Princess Margaret Cancer Centre ( Site 0310), Toronto, Ontario
CIUSSS de l'Est-de-l'Île-de-Montréal ( Site 0301), Montreal, Quebec
Jewish General Hospital ( Site 0303), Montreal, Quebec
Centre intégré de santé et de services sociaux du Bas Saint-Laurent- Hôpital régional de Rimouski ( Site 0308), Rimouski, Quebec
CHU de Quebec Universite Laval - Hopital du Saint-Sacrement ( Site 0302), Quebec, Not set
Oncovida ( Site 0453), Santiago., Region M. De Santiago
Clínica RedSalud Vitacura ( Site 0455), Santiago., Region M. De Santiago
FALP-UIDO ( Site 0451), Santiago, Region M. De Santiago
Pontificia Universidad Catolica de Chile ( Site 0454), Santiago, Region M. De Santiago
Bradfordhill ( Site 0452), Santiago, Region M. De Santiago
Bradford Hill Norte ( Site 0456), Antofagasta, Not set
Fundacion Colombiana de Cancerología Clinica Vida ( Site 0506), Medellín, Antioquia
Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 0501), Valledupar, Cesar
IMAT S.A.S ( Site 0502), Monteria., Cordoba
FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0507), Bogota, Distrito Capital De Bogota
Fundación Valle del Lili ( Site 0508), Cali, Valle Del Cauca
CIMCA ( Site 0551), San José, San Jose
Hospital Metropolitano - Sede Lindora ( Site 0550), Santa Ana, San Jose
ICIMED ( Site 0552), San Jose, Not set
Nemocnice Ceske Budejovice-Onkologicke oddeleni ( Site 1138), Ceske Budejovice, Jihocesky Kraj
Fakultni nemocnice Ostrava-Klinika onkologicka ( Site 1134), Ostrava-Poruba, Moravskoslezsky Kraj
Fakultni nemocnice Olomouc-Onkologicka klinika ( Site 1132), Olomouc, Olomoucky Kraj
Fakultni nemocnice v Motole-Onkologicka klinika 2. LF UK a FN Motol ( Site 1136), Praha, Praha 5
Fakultni nemocnice Kralovske Vinohrady-Onkologická klinika ( Site 1135), Praha 10, Not set
Rigshospitalet ( Site 1180), Copenhagen, Hovedstaden
Nordsjællands Hospital - Hillerød ( Site 1184), Hillerod, Hovedstaden
Næstved Sygehus ( Site 1182), Naestved, Sjaelland
Odense Universitetshospital ( Site 1181), Odense C, Syddanmark
Vejle Sygehus ( Site 1183), Vejle, Syddanmark
Centre François Baclesse ( Site 1250), Caen, Calvados
Centre de Cancérologie du Grand Montpellier ( Site 1244), Montpellier, Languedoc-Roussillon
Hôpital privé du Confluent SAS-Service d'oncologie médicale ( Site 1242), Nantes, Loire-Atlantique
Pitie Salpetriere University Hospital ( Site 1249), Paris, Orne
Hopital Prive Jean Mermoz-Oncology ( Site 1246), Lyon, Rhone-Alpes
Centre Hospitalier Universitaire de Poitiers-Pôle régional de cancérologie ( Site 1243), Poitiers, Vienne
Institut Curie-Oncology medical Department ( Site 1240), Paris, Not set
SRH Wald-Klinikum Gera-Zentrum für klinische Studien ( Site 1315), Gera, Thuringen
Helios Klinikum Berlin-Buch-Klinik für Gynäkologie und Geburtshilfe ( Site 1314), Berlin, Not set
Errikos Dunant Hospital Center ( Site 1348), Athens, Attiki
Aretaieio Hospital Oncology Unit ( Site 1345), Athens, Attiki
Hygeia Hospital ( Site 1346), Marousi, Attiki
University General Hospital of Larissa ( Site 1343), Larissa, Thessalia
Agios Loukas Clinic ( Site 1347), Thessaloniki, Not set
European Interbalkan Medical Center ( Site 1341), Thessaloniki, Not set
Queen Mary Hospital ( Site 2040), Hksar, Not set
Prince of Wales Hospital ( Site 2041), Shatin, Not set
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Onkoterápiás Klinika ( Site 1379), Szeged, Csongrad
Somogy Vármegyei Kaposi Mór Oktató Kórház-Oncology center ( Site 1371), Kaposvár, Somogy
Zala Vármegyei Szent Rafael Kórház-Onkológiai osztály ( Site 1372), Zalaegerszeg, Zala
Semmelweis Egyetem-Belgyógyászati és Onkológiai Klinika ( Site 1381), Budapest, Not set
Budapesti Uzsoki Utcai Kórház-Onkoradiológiai Osztály ( Site 1373), Budapest, Not set
Debreceni Egyetem Klinikai Kozpont-Onkológiai Klinika ( Site 1375), Debrecen, Not set
All India Institute of Medical Sciences ( Site 2051), New Delhi, Delhi
Rajiv Gandhi Cancer Institute And Research Centre-Department of Clinical Research ( Site 2052), New Delhi, Delhi
Tata Memorial Hospital-Medical Oncology ( Site 2053), Mumbai, Maharashtra
Kokilaben Dhirubhai Ambani Hospital & Medical Research Institute-Centre for cancer ( Site 2056), Mumbai, Maharashtra
Bon Secours Cork Hospital ( Site 1422), Cork, Not set
St. Vincent's University Hospital-Medical Oncology Research Department ( Site 1420), Dublin, Not set
Mater Misericordiae University Hospital-Clinical Trials Research Unit ( Site 1423), Dublin, Not set
Rambam Health Care Campus-Oncology Division ( Site 1452), Haifa, Not set
Hadassah Medical Center ( Site 1451), Jerusalem, Not set
Rabin Medical Center ( Site 1453), Petah Tikva, Not set
Sheba Medical Center ( Site 1450), Ramat Gan, Not set
IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori" ( Site 1480), Meldola, Forli-Cesena
CRO-IRCCS ( Site 1478), Aviano, Friuli-Venezia Giulia
Istituto Europeo di Oncologia IRCCS-Divisione di Senologia Medica ( Site 1475), Milano, Lombardia
Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1472), Milan, Lombardia
Istituto Clinico Humanitas ( Site 1476), Rozzano, Milano
IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola ( Site 1474), Bologna, Not set
Ospedale San Martino ( Site 1479), Genova, Not set
Ospedale San Raffaele-Oncologia Medica ( Site 1471), Milano, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 1477), Roma, Not set
Nagoya City University Hospital ( Site 2474), Nagoya, Aichi
Hokkaido University Hospital ( Site 2460), Sapporo, Hokkaido
Tokai University Hospital ( Site 2473), Isehara, Kanagawa
St. Marianna University Hospital ( Site 2465), Kawasaki, Kanagawa
Kitasato University Hospital ( Site 2471), Sagamihara, Kanagawa
Kanagawa Cancer Center ( Site 2472), Yokohama, Kanagawa
Mie University Hospital ( Site 2483), Tsu, Mie
Tohoku University Hospital ( Site 2482), Sendai, Miyagi
The University of Osaka Hospital ( Site 2476), Suita, Osaka
Saitama Medical University International Medical Center ( Site 2462), Hidaka, Saitama
Juntendo University Hospital ( Site 2468), Bunkyo, Tokyo
Cancer Institute Hospital of JFCR ( Site 2464), Koto, Tokyo
Showa Medical University Hospital ( Site 2466), Shinagawa, Tokyo
Tokyo Medical University Hospital ( Site 2467), Shinjuku, Tokyo
National Center for Global Health and Medicine ( Site 2469), Shinjuku, Tokyo
Fukushima Medical University Hospital ( Site 2461), Fukushima, Not set
Gifu University Hospital ( Site 2486), Gifu, Not set
Hiroshima City Hiroshima Citizens Hospital ( Site 2478), Hiroshima, Not set
Social medical corporation Hakuaikai Sagara Hospital ( Site 2481), Kagoshima, Not set
Kumamoto University Hospital ( Site 2480), Kumamoto, Not set
Kyoto University Hospital ( Site 2475), Kyoto, Not set
Okayama University Hospital ( Site 2485), Okayama, Not set
Osaka International Cancer Institute ( Site 2477), Osaka, Not set
Seoul National University Hospital-Internal Medicine ( Site 2353), Seoul, Not set
Severance Hospital, Yonsei University Health System-Medical oncology ( Site 2350), Seoul, Not set
Asan Medical Center-Department of Oncology ( Site 2352), Seoul, Not set
Samsung Medical Center-Division of Hematology/Oncology ( Site 2351), Seoul, Not set
Hospital Sultan Ismail ( Site 2153), Johor Bahru, Johor
Sarawak General Hospital ( Site 2154), Kuching, Sarawak
Pantai Hospital Kuala Lumpur ( Site 2151), Kuala Lumpur, Not set
Health Pharma Professional Research S.A. de C.V: ( Site 0598), Ciudad de México, Distrito Federal
Grupo Médico ASSET-Clinical Research ( Site 0596), Mexico City, Distrito Federal
CIO - Centro de Inmuno-Oncología de Occidente ( Site 0592), Guadalajara, Jalisco
Hospital Universitario "Dr. Jose Eleuterio Gonzalez"-Servicio de Oncología ( Site 0590), Monterrey, Nuevo Leon
CENTRO MEDICO ZAMBRANO HELLION-Centro de Cáncer de Mama ( Site 0595), San Pedro Garza Garcia, Nuevo Leon
Ziekenhuis Rijnstate-Rijnstate Centrum Oncologisch Onderzoek ( Site 1524), Arnhem, Gelderland
Maastricht UMC+-Medical Oncology ( Site 1522), Maastricht, Limburg
Amphia Ziekenhuis, locatie Breda Molengracht-oncologie ( Site 1523), Breda, Noord-Brabant
Catharina Ziekenhuis ( Site 1526), Eindhoven, Noord-Brabant
Nederlands Kanker Instituut - Antoni van Leeuwenhoek (NKI-AVL)-medical oncology ( Site 1520), Amsterdam, Noord-Holland
Isala, locatie Zwolle ( Site 1525), Zwolle, Overijssel
Meander Medisch Centrum ( Site 1521), Amersfoort, Utrecht
Auckland City Hospital ( Site 2031), Auckland, Not set
Clinica Vallesur - AUNA ( Site 0652), Arequipa, Ariqipa
Hospital Militar Central Luis Arias Schereiber ( Site 0651), Jesús María, Lima
Oncosalud ( Site 0650), Lima, Muni Metro De Lima
IPOR Instituto Peruano de Oncología & Radioterapia ( Site 0653), Lima, Not set
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 1582), Bydgoszcz, Kujawsko-pomorskie
Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 1584), Siedlce, Mazowieckie
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworów Piersi i Chirurgii ( Site 1580), Warszawa, Mazowieckie
Mazowiecki Szpital Onkologiczny ( Site 1581), Wieliszew, Mazowieckie
Mrukmed-Mrukmed ( Site 1592), Rzeszow, Podkarpackie
Bialostockie Centrum Onkologii ( Site 1585), Bialystok, Podlaskie
Szpitale Pomorskie Sp. z o. o.-Oddział Onkologii Klinicznej ( Site 1593), Gdynia, Pomorskie
Narodowy Instytut Onkologii - Oddzial w Gliwicach-Centrum Diagnostyki i Leczenia Chorob Piersi ( Site 1590), Gliwice, Slaskie
Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zakl-Klinika Onkologii Klinicznej, Dzial Ch ( Site 1595), Kielce, Swietokrzyskie
Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie-Oddzial Dzienny Chemioterapii ( Site 1583), Koszalin, Zachodniopomorskie
Zachodniopomorskie Centrum Onkologii ( Site 1588), Szczecin, Zachodniopomorskie
Unidade Local de Saude Amadora/Sintra - Hospital Prof Dr Fernando Fonseca ( Site 1663), Lisbon, Lisboa
Unidade Local de Saude de Santa Maria - Hospital de Santa Maria ( Site 1661), Lisboa, Not set
Instituto Português de Oncologia do Porto Francisco Gentil, EPE ( Site 1662), Porto, Not set
Puerto Rico Medical Research Center LLC ( Site 0675), Hato Rey, Not set
UPR Comprehensive Cancer Center-Comprehensive Cancer Center Hospital ( Site 0677), San Juan, Not set
Spitalul Clinic Filantropia ( Site 1703), București, Bucuresti
SC Radiotherapy Center Cluj SRL-Oncologie Medicala ( Site 1702), Florești, Cluj
Centrul Medical Neolife- Baneasa ( Site 1704), Bucuresti, Not set
Institutul Oncologic Cluj ( Site 1701), Cluj, Not set
National University Hospital ( Site 2250), Singapore, Central Singapore
Mount Alvernia ICON Cancer Center ( Site 2251), Singapore, North East
CANCERCARE LANGENHOVEN DRIVE ONCOLOGY CENTRE ( Site 2905), Port Elizabeth, Eastern Cape
Curo Oncology ( Site 2908), Pretoria, Gauteng
Sandton Oncology Medical Group (Pty) Ltd ( Site 2911), Sandton, Gauteng
Cancercare Rondebosch Oncology-Clinical trials ( Site 2904), Rondebosch, Western Cape
HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID ( Site 1758), Pozuelo de Alarcon, Madrid
HOSPITAL CLINICO DE VALENCIA-Oncology ( Site 1752), Valencia, Valenciana, Comunitat
Hospital Universitari Vall d'Hebron-Oncology ( Site 1750), Barcelona, Not set
Hospital Universitario Reina Sofia-Oncologia Medica ( Site 1754), Cordoba, Not set
Hospital Beata María Ana-oncology ( Site 1755), Madrid, Not set
HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON-ONCOLOGY ( Site 1756), Madrid, Not set
Hospital Universitario Virgen Macarena ( Site 1757), Sevilla, Not set
Karolinska Universitetssjukhuset Solna ( Site 1801), Stockholm, Stockholms Lan
Akademiska sjukhuset ( Site 1802), Uppsala, Uppsala Lan
Södra Älvsborgs Sjukhus Borås ( Site 1803), Borås, Vastra Gotalands Lan
University Hospital Basel-Gynecology & Gynecologic Oncology ( Site 1844), Basel, Basel-Stadt
Spital Thun ( Site 1840), Thun, Berne
Brust-Zentrum ( Site 1841), Zürich, Zurich
Changhua Christian Hospital ( Site 2410), Changhua, Not set
Chang Gung Memorial Hospital at Kaohsiung-Oncology and Hematology ( Site 2413), Kaohsiung, Not set
National Cheng Kung University Hospital-Surgery ( Site 2411), Tainan, Not set
National Taiwan University Hospital-Oncology ( Site 2415), Taipei, Not set
Mackay Memorial Hospital ( Site 2412), Taipei, Not set
Chang Gung Medical Foundation-Linkou Branch-General Surgery ( Site 2414), Taoyuan, Not set
Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi ( Site 1878), Yenimahalle, Ankara
Medipol Mega Universite Hastanesi-oncology ( Site 1875), Stanbul, Istanbul
Adana Medical Park Seyhan Hastanesi-Medikal Onkoloji ( Site 1876), Adana, Not set
Hacettepe Universite Hastaneleri-oncology hospital ( Site 1870), Ankara, Not set
Memorial Ankara Hastanesi-Medical Oncology ( Site 1874), Ankara, Not set
Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 1871), Ankara, Not set
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 1872), Istanbul, Not set
Samsun Medical Park Hastanesi-medical oncology ( Site 1873), Samsun, Not set
North West Cancer Centre ( Site 1944), Londonderry, Derry And Strabane
The Royal Cornwall Hospital ( Site 1943), Truro, England
St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 1940), London, London, City Of
University College London Hospital-Cancer Clinical Trials Unit ( Site 1942), London, London, City Of
Blackpool Victoria Hospital ( Site 1941), Blackpool, Not set
City Hospital, Nottingham University Hospitals NHS Trust ( Site 1945), Nottingham, Not set
Conditions: Breast Neoplasms
Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to ER+/HER-2- Breast Cancer
Recruiting
This is a multi-site, global, open-label study that includes a phase 1b evaluation of elacestrant in combination with abemaciclib in women and men with brain metastases from estrogen receptor (ER)-positive, human epidermal growth factor receptor-2 (HER-2) negative breast cancer. Phase 1b was designed to select the recommended phase 2 dose and is followed by an ongoing phase 2 evaluation of elacestrant in combination with abemaciclib in patients with active brain metastases from ER-positive, HER-... Read More
This is a multi-site, global, open-label study that includes a phase 1b evaluation of elacestrant in combination with abemaciclib in women and men with brain metastases from estrogen receptor (ER)-positive, human epidermal growth factor receptor-2 (HER-2) negative breast cancer. Phase 1b was designed to select the recommended phase 2 dose and is followed by an ongoing phase 2 evaluation of elacestrant in combination with abemaciclib in patients with active brain metastases from ER-positive, HER-2 negative breast cancer. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/06/2025
Locations: Providence Medical Foundation, Fullerton, California +83 locations
Providence Medical Foundation, Fullerton, California
California Research Institute, Los Angeles, California
Carle Cancer Center, Urbana, Illinois
Dana-Farber Cancer Institute, Boston, Massachusetts
Henry Ford Hospital, Detroit, Michigan
Miami Valley Hospital South, Centerville, Ohio
Oregon Health & Science University, Portland, Oregon
SCRI Oncology Partners, Nashville, Tennessee
University of Texas MD Anderson Cancer Center, Houston, Texas
UT Health San Antonio University of Texas, San Antonio, Texas
Virginia Cancer Institute, Norfolk, Virginia
Antwerp University Hospital, Edegem, Not set
Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg, Leuven, Not set
Universite Catholique de Louvain (UCL) - Cliniques Universitaires Saint-Luc, Woluwe-Saint-Lambert, Not set
Institut de Cancerologie de l'Ouest site Paul Papin, Angers, Not set
Hôpital Morvan - CHRU de Brest - cancérologie et d'hématologie, Brest, Not set
Centre Francois Baclesse - Oncologie Medicale - Cancerolo, Caen, Not set
Centre Jean Perrin, Clermont-Ferrand, Not set
Centre Léon Bérard - Département Oncologie Médicale, Lyon, Not set
Centre de Cancerologie du Grand Montpellier, Montpellier, Not set
Hôpital de la Pitiê Salpêtriêre, Paris, Not set
Centre Hospitalier Universitaire de Poitiers, Poitiers, Not set
Institut Claudius Regaud, Toulouse, Not set
Klinikum Bayreuth GmbH, Bayreuth, Not set
Uniklinik Koeln - Klinik und Poliklinik fuer Frauenheilkunde, Cologne, Not set
Universitatsklinikum Carl Gustav Carus, Dresden, Not set
Universitaetsklinikum Duesseldorf, Düsseldorf, Not set
Universitätsklinikum Erlangen, Erlangen, Not set
Medizinische Hochschule Hannover, Hannover, Not set
Universitätsklinikum Leipzig, Leipzig, Not set
Klinikum Worms gGmbH, Worms, Not set
Helios Klinikum Wuppertal, Wuppertal, Not set
National and Capodistrian University of Athens - University General Hospital Attikon, Athens, Not set
Metropolitan Hospital [Oncology], Piraeus, Not set
EUROMEDICA General Clinic of Thessaloniki, Thessaloníki, Not set
Interbalkan European Medical Center, Thessaloníki, Not set
AOU Ospedali Riuniti Umberto I-G.M.Lancisi -G.Salesi, Ancona, Not set
Istituto di Candiolo, IRCCS, Candiolo, Not set
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori - IRST IRCCS, Meldola, Not set
A. O. Ospedali Riuniti Parpardo, Piemonte, Messina, Messina, Not set
IEO - Istituto Europeo di Oncologia, IRCCS, Milano, Not set
Azienda Ospedaliero-Universitaria di Modena, Policlinico di Modena, Modena, Not set
Ospedale San Gerardo, ASST di Monza, IRCCS, Monza, Not set
Azienda Ospedaliera Universitaria Federico II, Napoli, Not set
Istituto Nazionale dei Tumori - Fondazione Pascale, IRCCS, Napoli, Not set
Istituto Oncologico Veneto IOV - IRCCS, Padova, Not set
IRCCS Policlinico San Matteo, Università degli studi di Pavia, Pavia Fondazione IRCCS Policlinico San Matteo, Pavia, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Not set
Azienda Ospedaliera Santa Maria di Terni, Terni, Not set
AOU Città della Salute e della Scienza di Torino, Ospedale Molinette, Torino, Not set
Asan Medical Center, Seoul, Not set
Gangnam Severance Hospital, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Ewha Womans University MokDong Hospital, Seoul, Not set
Seoul National University Bundang Hospital, Seoul, Not set
Seoul National University Hospital, Seoul, Not set
University Hospital Reina Sofía, Córdoba, Andalusia
University Hospital Ramón y Cajal, Madrid, Community Of Madrid
University Hospital 12 de Octubre, Madrid, Community Of Madrid
Clara Campal Comprehensive Cancer Center (CIOCC), Madrid, Community Of Madrid
University Clinical Hospital Virgen de la Arrixaca, El Palmar, Murcia
Hospital Clinic De Barcelona, Barcelona, Not set
Hospital Universitari Vall D Hebron, Barcelona, Not set
Clinica Universidad de Navarra, Madrid, Not set
Hospital Clínico San Carlos, Madrid, Not set
Hospital Universitario Quirónsalud Madrid, Madrid, Not set
Clinica Universidad de Navarra, Pamplona, Not set
Complexo Hospitalario Universitario De Santiago, Santiago De Compostela, Not set
Fundación Instituto Valenciano De Oncología, Valencia, Not set
Hospital Universitario Virgen del Rocío, Valencia, Not set
Adana Sehir Hastanesi, Adana, Not set
Ankara Bilkent Sehir Hastanesi Tibbi Onkoloji Klinigi, Ankara, Not set
Ankara University Medical Faculty, Ankara, Not set
Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi, Ankara, Not set
Gulhane Egitim ve Arastirma Hastanesi Tibbi Onkoloji Klinigi, Ankara, Not set
Hacettepe University Medical Faculty, Ankara, Not set
Memorial Ankara Hastanesi Tibbi Onkoloji, Ankara, Not set
Ege University Medical Faculty, Bornova, Not set
Prof. Dr. Suleyman Yalcin Sehir Hastanesi, Istanbul, Not set
University Hosiptals of Leicester NHS Trust -Glenfield Hospital, Leicester, Not set
The Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool, Not set
Guy's and St Thomas' NHS Foundation Trust, London, Not set
University College London Hospitals NHS Foundation Trust - University College Hospital (UCH) - Macmillan Cancer Centre, London, Not set
The Christie NHS Foundation Trust - Medical Oncology, Manchester, Not set
Conditions: Breast Neoplasms, Brain Neoplasms, Neoplasms by Site, Neoplasms, Breast Diseases, Central Nervous System Neoplasms, Brain Diseases, Central Nervous System Diseases
A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors
Recruiting
This clinical trial is studying solid tumor cancers. A solid tumor is one that starts in part of your body like your lungs or liver instead of your blood. Once they've grown bigger in one spot or spread to other parts of the body, they're harder to treat. This is called advanced or metastatic cancer.
Participants in this study must have breast cancer or gastric cancer. Participants must have tumors that have HER2 on them. This allows the cancer to grow more quickly or spread faster. There are f... Read More
This clinical trial is studying solid tumor cancers. A solid tumor is one that starts in part of your body like your lungs or liver instead of your blood. Once they've grown bigger in one spot or spread to other parts of the body, they're harder to treat. This is called advanced or metastatic cancer.
Participants in this study must have breast cancer or gastric cancer. Participants must have tumors that have HER2 on them. This allows the cancer to grow more quickly or spread faster. There are few treatment options for patients with advanced or metastatic solid tumors that express HER2.
This clinical trial uses an experimental drug called disitamab vedotin (DV). Disitamab vedotin is a type of antibody drug conjugate or ADC. ADCs are designed to stick to cancer cells and kill them.
This clinical trial uses a drug called tucatinib, which has been approved to treat cancer in the United States and some other countries. This drug is sold under the brand name TUKYSA®.
This study will test how safe and how well DV with tucatinib works for participants with solid tumors. This study will also test what side effects happen when participants take these drugs. A side effect is anything a drug does to the body besides treating the disease. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/06/2025
Locations: Banner-University Medical Center Tucson Campus, Tucson, Arizona +122 locations
Banner-University Medical Center Tucson Campus, Tucson, Arizona
Banner-University Medical Center Tucson Campus, Tucson, Arizona
Banner-University Medical Center Tucson, Tucson, Arizona
The University of Arizona Cancer Center-North Campus Pharmacy, Attn: Kelly Myrdal, Tucson, Arizona
University of Arizona Cancer Center - North Campus, Tucson, Arizona
The University of Arizona Cancer Center-Main, Tucson, Arizona
UC Irvine Medical Center, Orange, California
University of California, San Francisco | HDFCCC - Hematopoietic Malignancies, San Francisco, California
UCLA Department of Medicine - Hematology & Oncology, Santa Monica, California
Colorado West Healthcare System, dba Community Hospital, Grand Junction, Colorado
Colorado West Healthcare, dba Grand Valley Oncology, Grand Junction, Colorado
Danbury Hospital, Danbury, Connecticut
The Whittingham Cancer Center / Norwalk Hospital, Norwalk, Connecticut
Georgetown University Medical Center, Washington, District of Columbia
MedStar Georgetown University Hospital, Washington, District of Columbia
Moffitt Cancer Center - International Plaza, Tampa, Florida
H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida
Moffitt Cancer Center - McKinley Campus, Tampa, Florida
Moffitt McKinley Hospital, Tampa, Florida
Moffitt Cancer Center at Wesley Chapel, Wesley Chapel, Florida
Georgia Cancer Specialists - Athens, Athens, Georgia
Georgia Cancer Specialists - Annex, Atlanta, Georgia
Atlanta Cancer Care - Atlanta, Atlanta, Georgia
Georgia Cancer Specialists-Northside, Atlanta, Georgia
Northside Hospital, Inc.- Central Research Department, Atlanta, Georgia
Northside Hospital, Atlanta, Georgia
Georgia Cancer Specialists - Blairsville, Blairsville, Georgia
Georgia Cancer Specialists - Canton, Canton, Georgia
Atlanta Cancer Care - Cumming, Cumming, Georgia
Georgia Cancer Specialists - Cumming, Cumming, Georgia
Georgia Cancer Specialists - Decatur, Decatur, Georgia
Suburban Hematology-Oncology Associates - Duluth, Duluth, Georgia
Suburban Hematology-Oncology Associates- Lawrenceville, Lawrenceville, Georgia
Georgia Cancer Specialists - Macon, Macon, Georgia
Georgia Cancer Specialists - Marietta, Marietta, Georgia
Memorial Hospital, Shiloh, Illinois
Siteman Cancer Center - Shiloh, Shiloh, Illinois
Massachusetts General Hospital., Boston, Massachusetts
Brigham and Women's Hospital, Boston, Massachusetts
Dana Farber Cancer Institute, Boston, Massachusetts
Dana Farber Cancer Institute- Chestnut Hill, Newton, Massachusetts
Siteman Cancer Center - West County, Creve Coeur, Missouri
Siteman Cancer Center - North County, Florissant, Missouri
Saint Luke's Cancer Institute LLC, Kansas City, Missouri
Saint Luke's Hospital Investigational Pharmacy, Kansas City, Missouri
St Lukes Hospital, Kansas City, Missouri
Barnes-Jewish Hospital, Saint Louis, Missouri
Washington University in St Louis., Saint Louis, Missouri
Washington University School of Medicine - Siteman Cancer Center, Saint Louis, Missouri
Siteman Cancer Center - South County, Saint Louis, Missouri
Siteman Cancer Center - St Peters, Saint Peters, Missouri
Renown Regional Medical Center, Reno, Nevada
San Juan Oncology Associates, Farmington, New Mexico
Memorial Sloan Kettering Cancer Center - Main Hospital, New York, New York
Zangmeister Cancer Center, Columbus, Ohio
Saint Francis Hospital / Bon Secours - South Carolina, Greenville, South Carolina
Sarah Cannon Research Institute - Pharmacy, Nashville, Tennessee
SCRI Oncology Partners, Nashville, Tennessee
Tennessee Oncology-Nashville/Sarah Cannon Research Institute, Nashville, Tennessee
Parkland Health and Hospital System, Dallas, Texas
University of Texas Southwestern Medical Center - Simmons Cancer Center, Dallas, Texas
University of Texas Southwestern Medical Center-Simmons Cancer Center Pharmacy, Dallas, Texas
University of Texas Southwestern Medical Center Simmons Cancer Center - Redbird, Dallas, Texas
University of Texas Southwestern Medical Center Clinical Lab-Zale Lipshy University Hospital, Dallas, Texas
University of Texas Southwestern Medical Center-William P. Clements Jr. University Hospital, Dallas, Texas
University of Texas Southwestern Medical Center, Dallas, Texas
University of Texas Southwestern Simmons Cancer Center - Fort Worth, Fort Worth, Texas
University of Texas Southwestern Medical Center Simmons Cancer Center - Richardson/Plano, Richardson, Texas
Harborview Medical Center, Seattle, Washington
Fred Hutchinson Cancer Center / Seattle Cancer Care Alliance / University of Washington, Seattle, Washington
University of Washington Medical Center, Seattle, Washington
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison, Wisconsin
Carbone Cancer Center / University of Wisconsin, Madison, Wisconsin
Peninsula & South Eastern Hematology and Oncology Group (PASO), Frankston, Victoria
Slade Pharmacy Frankston, Frankston, Victoria
Slade Health, Mount Waverley, Victoria
Peninsula & South Eastern Hematology and Oncology Group (PASO), Frankston, Not set
BC Cancer Kelowna., Kelowna, British Columbia
Ottawa Hospital Cancer Centre, Ottawa, Ontario
Sunnybrook Health Sciences Centre, Toronto, Ontario
University Health Network, Princess Margaret Hospital, Toronto, Ontario
Universitatsklinikum Essen, Essen, Not set
Universitatsklinikum Heidelberg, Heidelberg, Not set
Klinikums rechts der Isar der TU München, Muenchen, Not set
A.O.U. Federico II, Napoli, Campania
Azienda Ospedaliera Universitaria (AOU) Federico II, Napoli, Campania
Istituto Nazionale Tumori IRCCS Fondazione G. Pascale., Napoli, Campania
Istituto Europeo di Oncologia, Milano, Lombardia
Niguarda Ca' Granda Hospital, Milano, Lombardia
Humanitas Istituto Clinico Catanese, Misterbianco (CT), Sicilia
Azienda Ospedaliera Universitaria Integrata di Verona., Verona, Veneto
A.O.U. Federico II- U.O.C. Diagnostica per lmmagini e Radioterapia, Napoli, Not set
Dong-A University Hospital, Busan, Other
National Cancer Center, Goyang-si, Other
Chungbuk National University Hospital, Cheongju-si, Not set
Gachon University Gil Medical Center, Incheon, Not set
Seoul National University Bundang Hospital, Seongnam-si, Not set
Korea University Anam Hospital, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Seoul National University Hospital, Seoul, Not set
Severance Hospital Yonsei University Health System, Seoul, Not set
St. Vincent's Hospital, The Catholic University of Korea, Suwon-si, Not set
Quirén Salud Barcelona, Barcelona, Not set
Hospital Universitari Vall d´Hebron, Barcelona, Not set
CETIR Grup Medic, Barcelona, Not set
Hospital Universitario de Basurto, Bilbao, Not set
Grupo Hospitalario QuironSalud, Erandio Bizkaia, Not set
L'Institut Catala d'Oncologia., L'Hospitalet de Llobregat, Not set
Farmacia-Ensayos. Planta S - Hospital Universitario HM Sanchinarro-CIOCC-START Madrid, Madrid, Not set
START Madrid-CIOCC_Hospital HM Sanchinarro, Madrid, Not set
Ecg Medica Sl, Valencia, Not set
Hospital Clinico Universitario de Valencia, Valencia, Not set
National Cheng Kung University Hospital, Tainan, Not set
National Cheng Kung University Hospital, Tainan, Not set
National Taiwan University Hospital, Taipei, Not set
National Taiwan University Hospital, Taipei, Not set
National Taiwan University Cancer Center, Taipei, Not set
The Royal Marsden Hospital, Sutton, Surrey
St Bartholomew's Hospital, London, Not set
The Royal Marsden Hospital, London, Not set
The Royal Marsden NHS Foundation Trust (RM), London, Not set
The Christie NHS Foundation Trust, Manchester, Not set
The Royal Marsden NHS Foundation Trust, Sutton, Not set
Conditions: Breast Neoplasms, Gastroesophageal Junction Adenocarcinoma, HER2 Low Breast Neoplasms, HER2 Positive Breast Neoplasms, Stomach Neoplasms, Triple Negative Breast Neoplasms, Metastatic Breast Cancer, Metastatic Gastric Cancer, Advanced Breast Cancer, Advanced Gastric Cancer
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
Recruiting
The purpose of this study is to assess the efficacy and safety of iza-bren, a bi-specific antibody-drug conjugate against EGFR and HER3 with a topoisomerase inhibitor payload versus treatment of physician's choice (TPC) (paclitaxel, nab-paclitaxel, carboplatin plus gemcitabine, and capecitabine) for the treatment of first-line metastatic triple-negative breast cancer (TNBC) or estrogen receptor (ER)-low, human epidermal growth factor receptor 2 (HER2)-negative BC patients who are not candidates... Read More
The purpose of this study is to assess the efficacy and safety of iza-bren, a bi-specific antibody-drug conjugate against EGFR and HER3 with a topoisomerase inhibitor payload versus treatment of physician's choice (TPC) (paclitaxel, nab-paclitaxel, carboplatin plus gemcitabine, and capecitabine) for the treatment of first-line metastatic triple-negative breast cancer (TNBC) or estrogen receptor (ER)-low, human epidermal growth factor receptor 2 (HER2)-negative BC patients who are not candidates for anti-PD(L)1 therapy and endocrine therapies. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/24/2025
Locations: Local Institution - 0303, Hot Springs, Arkansas +241 locations
Local Institution - 0303, Hot Springs, Arkansas
Local Institution - 0307, Cerritos, California
Local Institution - 0308, Cerritos, California
Local Institution - 0309, Cerritos, California
Local Institution - 0311, Long Beach, California
Local Institution - 0290, Los Angeles, California
Local Institution - 0283, Los Angeles, California
Local Institution - 0328, Whittier, California
Local Institution - 0289, Aurora, Colorado
Local Institution - 0304, Newark, Delaware
Local Institution - 0282, Miami, Florida
Local Institution - 0296, Pembroke Pines, Florida
Local Institution - 0294, Atlanta, Georgia
Local Institution - 0278, Chicago, Illinois
Local Institution - 0280, Chicago, Illinois
Decatur Memorial Hospital, Decatur, Illinois
Local Institution - 0324, O'Fallon, Illinois
Local Institution - 0286, Covington, Louisiana
Local Institution - 0288, Boston, Massachusetts
Local Institution - 0287, Boston, Massachusetts
Local Institution - 0313, Minneapolis, Minnesota
Local Institution - 0284, Kansas City, Missouri
Local Institution - 0312, New York, New York
Local Institution - 0279, New York, New York
Clinical Research Alliance, Westbury, New York
Local Institution - 0285, White Plains, New York
Local Institution - 0276, Durham, North Carolina
Local Institution - 0316, Eugene, Oregon
Local Institution - 0310, Philadelphia, Pennsylvania
Local Institution - 0281, Greenville, South Carolina
Local Institution - 0315, Austin, Texas
Local Institution - 0314, Houston, Texas
Local Institution - 0305, Tyler, Texas
Local Institution - 0277, Midlothian, Virginia
Local Institution - 0301, Roanoke, Virginia
Local Institution - 0302, Winchester, Virginia
Local Institution - 0345, Buenas Aires, Buenos Aires
Local Institution - 0011, Ciudad autónoma de Buenos Aires, Buenos Aires
Local Institution - 0214, ABB, Ciudad Autónoma De Buenos Aires
Local Institution - 0143, Cordoba, Córdoba
Local Institution - 0137, Río Cuarto, Córdoba
Local Institution - 0142, Rosario, Santa Fe
Local Institution - 0317, Buenos Aires, Not set
Local Institution - 0346, Buenos Aires, Not set
Local Institution - 0012, Ciudad Autónoma de Buenos Aires, Not set
Local Institution - 0035, Brisbane, Queensland
Local Institution - 0197, Ballarat Central, Victoria
Local Institution - 0031, Heidelberg, Victoria
Local Institution - 0274, Melbourne, Victoria
Local Institution - 0028, Subiaco, Western Australia
Local Institution - 0292, Graz, Steiermark
Local Institution - 0268, Innsbruck, Tirol
Local Institution - 0267, Salzburg, Not set
Local Institution - 0270, St. Polten, Not set
Local Institution - 0269, Wien, Not set
Local Institution - 0187, Manaus, Amazonas
Local Institution - 0147, Fortaleza, Ceará
Local Institution - 0157, Vitória, Espírito Santo
Local Institution - 0199, Porto Alegre, Rio Grande Do Sul
Local Institution - 0164, São José do Rio Preto, São Paulo
Local Institution - 0153, Rio de Janeiro, Not set
Local Institution - 0144, São Paulo, Not set
Local Institution - 0149, São Paulo, Not set
Local Institution - 0218, Kelowna, British Columbia
Local Institution - 0217, Victoria, British Columbia
Local Institution - 0265, Ottawa, Ontario
Local Institution - 0215, Montréal, Quebec
Local Institution - 0219, Montréal, Quebec
Local Institution - 0350, Saint-Jerome, Quebec
Local Institution - 0216, Sherbrooke, Quebec
Local Institution - 0138, Santiago, Región Metropolitana De Santiago
Local Institution - 0021, Santiago, Región Metropolitana De Santiago
Local Institution - 0017, Santiago, Región Metropolitana De Santiago
Local Institution - 0018, Santiago, Región Metropolitana De Santiago
Local Institution - 0016, Viña del Mar, Valparaíso
Local Institution - 0195, Medellín, Antioquia
Local Institution - 0201, Rionegro, Antioquia
Local Institution - 0194, Barranquilla, Atlántico
Local Institution - 0182, Puerto Colombia, Atlántico
Local Institution - 0181, Montería, COR
Local Institution - 0327, Bogota, Cundinamarca
Local Institution - 0183, Cali, Valle Del Cauca
Local Institution - 0349, Medellin, Not set
Local Institution - 0089, Bordeaux, Aquitaine
Local Institution - 0272, Dijon, Côte-d'Or
Local Institution - 0098, Toulouse, Haute-Garonne
Local Institution - 0095, Montpellier, Hérault
Local Institution - 0099, Rennes, Ille-et-Vilaine
Local Institution - 0092, Saint Herblain, Loire-Atlantique
Local Institution - 0091, Reims, Marne
Local Institution - 0097, Villejuif, Paris
Local Institution - 0093, Marseille, Provence-Alpes-Côte-d'Azur
Local Institution - 0096, Clermont-Ferrand, Puy-de-Dôme
Local Institution - 0090, Lyon, Rhône-Alpes
Local Institution - 0094, Lille, Not set
Local Institution - 0088, Paris, Not set
Local Institution - 0320, Esslingen, Baden-Württemberg
Local Institution - 0256, Augsburg, Bayern
Local Institution - 0271, München, Bayern
Local Institution - 0306, Frankfurt, Hessen
Local Institution - 0333, Langen, Hessen
Local Institution - 0257, Hannover, Niedersachsen
Local Institution - 0293, Düsseldorf, Nordrhein-Westfalen
Local Institution - 0263, Essen, Nordrhein-Westfalen
Local Institution - 0254, Leipzig, Sachsen
Local Institution - 0255, Lübeck, Schleswig-Holstein
Local Institution - 0261, Berlin, Not set
Local Institution - 0260, Berlin, Not set
Local Institution - 0259, Bonn, Not set
Local Institution - 0258, Dresden, Not set
Local Institution - 0262, Heidelberg, Not set
Local Institution - 0291, Ulm, Not set
Local Institution - 0042, Athens, Attikí
Local Institution - 0038, Athens, Attikí
Local Institution - 0086, Heraklion, Irakleío
Local Institution - 0043, Athens, Not set
Local Institution - 0266, New Delhi, Delhi
Local Institution - 0206, New Delhi, Delhi
Local Institution - 0131, Mumbai, Maharashtra
Local Institution - 0134, Nagpur, Maharashtra
Local Institution - 0125, Chennai, Tamil Nadu
Local Institution - 0130, Hyderabad, Telangana
Local Institution - 0133, Varanasi, Uttar Pradesh
Local Institution - 0352, New Delhi, Not set
Local Institution - 0186, Petah Tikva, HaMerkaz
Local Institution - 0044, Ramat Gan, HaMerkaz
Local Institution - 0048, Hadera, HaTsafon
Local Institution - 0123, Haifa, HaTsafon
Local Institution - 0047, Jerusalem, Yerushalayim
Local Institution - 0051, Napoli, Campania
Local Institution - 0049, Bologna, Emilia-Romagna
Local Institution - 0057, Aviano, Friuli-Venezia Giulia
Local Institution - 0054, Genova, Liguria
Local Institution - 0053, Pontedera, Pisa
Local Institution - 0055, Prato, Toscana
Local Institution - 0052, Milano, Not set
Local Institution - 0058, Napoli, Not set
Local Institution - 0061, Novara, Not set
Local Institution - 0056, Padova, Not set
Local Institution - 0062, Roma, Not set
Local Institution - 0236, Nagoya, Aichi
Local Institution - 0230, Chiba-shi, Chiba
Local Institution - 0240, Matsuyama, Ehime
Local Institution - 0226, Otashi, Gunma
Local Institution - 0222, Sapporo, Hokkaido
Local Institution - 0232, Kanazawa, Ishikawa
Local Institution - 0234, Isehara, Kanagawa
Local Institution - 0237, Yokohama, Kanagawa
Local Institution - 0246, Tsu, Mie
Local Institution - 0223, Sendai-shi, Miyagi
Local Institution - 0238, Suita, Osaka
Local Institution - 0227, Hidaka, Saitama
Local Institution - 0224, Ina-machi, Saitama
Local Institution - 0231, Bunkyo-ku, Tokyo
Local Institution - 0229, Chuo-ku, Tokyo
Local Institution - 0228, Koto, Tokyo
Local Institution - 0245, Shinagawa, Tokyo
Local Institution - 0233, Shinjuku-ku, Tokyo
Local Institution - 0242, Fukuoka, Not set
Local Institution - 0225, Fukushima, Not set
Local Institution - 0243, Hiroshima, Not set
Local Institution - 0244, Kagoshima, Not set
Local Institution - 0235, Kyoto, Not set
Local Institution - 0241, Okayama, Not set
Local Institution - 0239, Osaka, Not set
Local Institution - 0066, Goyang-si, Kyǒnggi-do
Local Institution - 0067, Seongnam, Kyǒnggi-do
Local Institution - 0068, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0063, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0071, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0064, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0065, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0069, Daegu, Taegu-Kwangyǒkshi
Local Institution - 0264, Tijuana, Baja California
Local Institution - 0177, Mexico City, DIF
Local Institution - 0329, Mexico City, Distrito Federal
Local Institution - 0178, Guadalajara, Jalisco
Local Institution - 0175, Monterrey, Nuevo León
Local Institution - 0176, Monterrey, Nuevo León
Local Institution - 0173, Oaxaca de Juarez, Oaxaca
Local Institution - 0179, Merida, Yucatán
Local Institution - 0174, Chihuahua, Not set
Local Institution - 0074, Biala Podlaska, Lubelskie
Local Institution - 0072, Warszawa, Mazowieckie
Local Institution - 0220, Warszawa, Mazowieckie
Local Institution - 0076, Opole, Opolskie
Local Institution - 0189, Skórzewo, Wielkopolskie
Local Institution - 0221, Łódź, Łódzkie
Local Institution - 0198, Lisbon, Lisboa
Local Institution - 0106, Lisbon, Lisboa
Local Institution - 0109, Lisbon, Lisboa
Local Institution - 0124, Coimbra, Not set
Local Institution - 0141, Lisboa, Not set
Local Institution - 0111, Porto, Not set
Local Institution - 0253, Porto, Not set
Local Institution - 0212, Bistrita, Bistrița-Năsăud
Local Institution - 0213, Bucharest, București
Local Institution - 0079, Florești, Cluj
Local Institution - 0078, Craiova, Dolj
Local Institution - 0084, Ploiești, Prahova
Local Institution - 0211, Dumbravita, Timiș
Local Institution - 0085, Timișoara, Timiș
Local Institution - 0083, București, Not set
Local Institution - 0077, Cluj, Not set
Local Institution - 0081, Iași, Not set
Local Institution - 0080, Iași, Not set
Local Institution - 0351, East London, Eastern Cape
Local Institution - 0342, Parktown, Gauteng
Local Institution - 0336, Pretoria, Gauteng
Local Institution - 0341, Pretoria, Gauteng
Local Institution - 0340, Soweto, Gauteng
Local Institution - 0105, A Coruña, A Coruña [La Coruña]
Local Institution - 0100, Elche, Alicante
Local Institution - 0102, Barcelona, Barcelona [Barcelona]
Local Institution - 0172, Hospitalet, Barcelona [Barcelona]
Local Institution - 0140, Barcelona, Catalunya [Cataluña]
Local Institution - 0139, San Sebastian, Gipuzkoa
Local Institution - 0104, Madrid, Madrid, Comunidad De
Local Institution - 0108, Madrid, Madrid, Comunidad De
Local Institution - 0101, Malaga, Málaga
Local Institution - 0210, Valencia, Valenciana, Comunitat
Local Institution - 0107, Madrid, Not set
Local Institution - 0103, Sevilla, Not set
Local Institution - 0252, Malmö, Skåne Län [se-12]
Local Institution - 0026, Stockholm, Stockholms Län [se-01]
Local Institution - 0025, Uppsala, Uppsala Län [se-03]
Local Institution - 0024, Örebro, Örebro Län [se-18]
Local Institution - 0247, Linköping, Östergötlands Län [se-05]
Local Institution - 0250, st.Gallen, Sankt Gallen
Local Institution - 0249, Lausanne, Vaud
Local Institution - 0251, Zürich, Not set
Local Institution - 0323, Abu Dhabi, Abū Z̧aby
Local Institution - 0318, Abu Dhabi, Abū Z̧aby
Local Institution - 0322, Al Ain, Abū Z̧aby
Local Institution - 0319, Abu Dhabi, Not set
Local Institution - 0208, Truro, England
Local Institution - 0204, London, London, City Of
Local Institution - 0209, London, London, City Of
Local Institution - 0171, Belfast, Not set
Local Institution - 0004, London, Not set
Local Institution - 0001, Manchester, Not set
Local Institution - 0006, Nottingham, Not set
Conditions: Breast Neoplasms
A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer
Recruiting
The main purpose of this study is to measure how well imlunestrant works compared to standard hormone therapy in participants with early breast cancer that is estrogen receptor positive (ER+) and human epidermal receptor 2 negative (HER2-). Participants must have already taken endocrine therapy for two to five years and must have a higher-than-average risk for their cancer to return. Study participation could last up to 10 years.
The main purpose of this study is to measure how well imlunestrant works compared to standard hormone therapy in participants with early breast cancer that is estrogen receptor positive (ER+) and human epidermal receptor 2 negative (HER2-). Participants must have already taken endocrine therapy for two to five years and must have a higher-than-average risk for their cancer to return. Study participation could last up to 10 years. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/22/2025
Locations: USO - Southern Cancer Center, Daphne, Alabama +676 locations
USO - Southern Cancer Center, Daphne, Alabama
Clearview Cancer Institute, Huntsville, Alabama
Infirmary Cancer Care, Mobile, Alabama
Banner MD Anderson Cancer Center, Gilbert, Arizona
USO - Arizona Oncology Associates - HAL, Glendale, Arizona
St. Joseph's Hospital and Medical Center, Phoenix, Arizona
Mayo Clinic in Arizona - Phoenix, Phoenix, Arizona
TMC HealthCare, Tucson, Arizona
The University of Arizona Cancer Center - North Campus, Tucson, Arizona
Highlands Oncology Group, Springdale, Arkansas
UCSF - John Muir Health Cancer Center Berkeley, Berkeley, California
Washington Hospital Healthcare System, Fremont, California
Chao Family Comprehensive Cancer Center and Ambulatory Care (CIACC) - Irvine, Irvine, California
Loma Linda University Cancer Center, Loma Linda, California
Pacific Cancer Care, Monterey, California
St. Joseph Hospital, Orange, California
University of California, Irvine (UCI) Health - UC Irvine Medical Center, Orange, California
University of California Davis (UC Davis) Comprehensive Cancer Center, Sacramento, California
Kaiser Permanente San Diego Mission Road, San Diego, California
Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, California
UCSF Medical Center at Mission Bay, San Francisco, California
Saint Joseph's Medical Center, Stockton, California
Anschutz Cancer Pavilion, Aurora, Colorado
UCHealth Memorial Hospital, Colorado Springs, Colorado
UCHealth Harmony, Fort Collins, Colorado
Banner MD Anderson Cancer Center at North Colorado Medical Center, Greeley, Colorado
USO - Rocky Mountain Cancer Centers, Lakewood, Colorado
Banner MD Anderson Cancer Center at McKee Medical Center, Loveland, Colorado
Yale-New Haven Hospital, New Haven, Connecticut
Georgetown University Medical Center, Washington, District of Columbia
MedStar Washington Hospital Center, Washington, District of Columbia
AdventHealth Altamonte Springs, Altamonte Springs, Florida
Memorial Regional Hospital, Hollywood, Florida
Millennium Oncology Research Clinic, Hollywood, Florida
Mayo Clinic in Florida, Jacksonville, Florida
Miami Cancer Institute at Baptist Health, Inc., Miami, Florida
USO - Cancer Care Centers of Brevard, Palm Bay, Florida
USO - Woodlands Medical Specialists, Pensacola, Florida
Miami Cancer Institute - Plantation, Plantation, Florida
Tampa General Hospital, Tampa, Florida
Winship Cancer Institute, Emory University, Atlanta, Georgia
Northside Hospital, Atlanta, Georgia
Summit Cancer Care, PC, Savannah, Georgia
Kaiser Permanente Moanalua Medical Center, Honolulu, Hawaii
Kapiolani Medical Center for Women and Children, Honolulu, Hawaii
Northwestern Memorial Hospital, Chicago, Illinois
University of Illinois at Chicago, Chicago, Illinois
Illinois Cancer Care, Peoria, Illinois
Simmons Cancer Institute at SIU, Springfield, Illinois
The University of Kansas Cancer Center - Westwood, Westwood, Kansas
Ochsner Clinic Foundation, Covington, Louisiana
Pontchartrain Cancer Center, Hammond, Louisiana
Ochsner Clinic Foundation, New Orleans, Louisiana
York Hospital, York, Maine
Walter Reed National Military Medical Center, Bethesda, Maryland
Massachusetts General Hospital, Boston, Massachusetts
Dana-Farber Cancer Institute, Boston, Massachusetts
Mass General/North Shore Cancer Center, Danvers, Massachusetts
Southcoast Centers for Cancer Care, Fairhaven, Massachusetts
Dana-Farber Cancer Institute - Foxborough, Foxboro, Massachusetts
Dana-Farber Cancer Institute - Merrimack Valley, Methuen, Massachusetts
Dana-Farber/Brigham and Women's Cancer Center at Milford Regional Medical Center, Milford, Massachusetts
Mass General Cancer Center at Newton-Wellesley, Newton, Massachusetts
Dana-Farber/Brigham and Women's Cancer Center - South Shore Hospital, South Weymouth, Massachusetts
University of Massachusetts Medical School, Worcester, Massachusetts
M Health Fairview Cancer Clinic -Edina, Edina, Minnesota
USO - Minnesota Oncology Hematology, Minneapolis, Minnesota
Allina Health Cancer Institute, Minneapolis, Minnesota
Mayo Clinic in Rochester, Minnesota, Rochester, Minnesota
University of Missouri Hospital, Columbia, Missouri
Washington University, Saint Louis, Missouri
Nebraska Methodist Hospital, Omaha, Nebraska
Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Dana-Farber - New Hampshire Oncology/Hematology, Londonderry, New Hampshire
MD Anderson Cancer Center at Cooper, Camden, New Jersey
Astera Cancer Care, East Brunswick, New Jersey
Regional Cancer Care Associates, Little Silver, New Jersey
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
Capital Health Medical Center - Hopewell, Pennington, New Jersey
New Mexico Oncology Hematology Consultants Ltd., Albuquerque, New Mexico
University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico
New York Oncology Hematology Associate, Albany, New York
Maimonides Cancer Center, Brooklyn, New York
NYU Langone Health - Brooklyn, Brooklyn, New York
R.J. Zuckerberg Cancer Center, Lake Success, New York
Perlmutter Cancer Center at NYU Langone Hospital - Long Island, Mineola, New York
Northern Westchester Hospital, Mount Kisco, New York
Laura and Isaac Perlmutter Cancer Center, New York, New York
NYC Health + Hospitals / Bellevue, New York, New York
Memorial Sloan Kettering Cancer Center, New York, New York
Queens Medical Associates, Queens, New York
University of Rochester - Wilmot Cancer Institute, Rochester, New York
Phelps Hospital, Sleepy Hollow, New York
Staten Island University Hospital, Staten Island, New York
Clinical Research Alliance, Westbury, New York
Messino Cancer Center, Asheville, North Carolina
Aultman Hospital, Canton, Ohio
USO - Oncology Hematology Care, Cincinnati, Ohio
Mercy Health - St. Vincent Medical Center, Toledo, Ohio
St. Elizabeth Youngstown Hospital, Youngstown, Ohio
Good Samaritan Regional Medical Center, Corvallis, Oregon
USO - Oncology Associates of Oregon, Eugene, Oregon
Oregon Health and Science University, Portland, Oregon
USO - Compass Oncology, Tigard, Oregon
St. Luke's University Health Network, Bethlehem, Pennsylvania
USO - Alliance Cancer Specialists, PC, Horsham, Pennsylvania
Thomas Jefferson University - Clinical Research Institute, Philadelphia, Pennsylvania
Thomas Jefferson University, Aria Jefferson Health, Philadelphia, Pennsylvania
Asplundh Cancer Pavilion, Willow Grove, Pennsylvania
Lifespan Cancer Institute, Providence, Rhode Island
St Francis Cancer Center, Greenville, South Carolina
The West Clinic, PLLC dba West Cancer Center, Germantown, Tennessee
University of Tennessee Medical Center, Knoxville, Tennessee
Sarah Cannon Research Institute, Nashville, Tennessee
USO - Texas Oncology, Austin, Texas
USO - Texas Oncology, Dallas, Texas
USO - Texas Oncology, Dallas, Texas
USO - Texas Oncology, Denison, Texas
Texas Oncology - West Texas, El Paso, Texas
William Beaumont Army Medical Center, El Paso, Texas
USO - Texas Oncology, Flower Mound, Texas
Brooke Army Medical Center, Fort Sam Houston, Texas
John Peter Smith Hospital, Fort Worth, Texas
The Center for Cancer and Blood Disorders, Fort Worth, Texas
USO - Texas Oncology, Fort Worth, Texas
USO - Texas Oncology, Fredericksburg, Texas
USO - Texas Oncology, McAllen, Texas
USO - Texas Oncology, Plano, Texas
Scott & White Hospital - Round Rock, Round Rock, Texas
Mays Cancer Center, San Antonio, Texas
Baylor Scott & White Medical Center - Temple, Temple, Texas
US Oncology Research Network, The Woodlands, Texas
USO - Texas Oncology, Webster, Texas
University of Virginia Health System, Charlottesville, Virginia
Inova Schar Cancer Institute, Fairfax, Virginia
Fort Belvoir Community Hospital, Fort Belvoir, Virginia
Bon Secours St. Francis Medical Center, Midlothian, Virginia
USO - Virginia Oncology Associates, Norfolk, Virginia
USO - Virginia Cancer Specialists, Reston, Virginia
USO - Oncology & Hematology Associates of Southwest Virginia, Roanoke, Virginia
Centro de Oncología e Investigación de Buenos Aires, Berazategui, Buenos Aires
Instituto Alexander Fleming, Ciudad Autónoma de Buenos Aires, Buenos Aires
Instituto de Investigaciones Clínicas Mar del Plata, Mar del Plata, Buenos Aires
Go Centro Medico San Nicolás, San Nicolas, Buenos Aires
CIPREC, Buenos Aires, Ciudad Autónoma De Buenos Aires
Mautalen Salud e Investigación, Buenos Aires, Ciudad Autónoma De Buenos Aires
Fundación Cenit Para La Investigación En Neurociencias, Caba, Ciudad Autónoma De Buenos Aires
Clinica Adventista Belgrano, Caba, Ciudad Autónoma De Buenos Aires
Centro Medico Privado CEMAIC, Capital, Córdoba
Instituto Médico Río Cuarto, Río Cuarto, Córdoba
Clinica Viedma S. A, Viedma, Río Negro
Fundacion Estudios Clinicos, Rosario, Santa Fe
Centro Medico San Roque, San Miguel de Tucumán, Tucumán
Investigaciones Clinicas Moleculares (ICM), Buenos Aires, Not set
Centro Oncologico Korben, Buenos Aires, Not set
Fundación Respirar, Buenos Aires, Not set
Fundación CORI para la Investigación y Prevención del Cáncer, La Rioja, Not set
Fundacion Scherbovsky, Mendoza, Not set
Centro Polivalente de Asistencia e Investigacion Clinica - CER San Juan, San Juan, Not set
Instituto San Marcos, San Juan, Not set
Coffs Harbour Health Campus, Coffs Harbour, New South Wales
St Vincent's Hospital, Darlinghurst, New South Wales
Gosford Hospital, Gosford, New South Wales
Liverpool Hospital, Liverpool, New South Wales
Lake Macquarie Private Hospital, Newcastle, New South Wales
Mater Hospital Sydney, Sydney, New South Wales
Royal Darwin Hospital, Tiwi, Northern Territory
Mackay Base Hospital, Mackay, Queensland
Gold Coast University Hospital, Southport, Queensland
The Townsville Hospital, Townsville, Queensland
Hervey Bay Hospital, Urraween, Queensland
The Queen Elizabeth Hospital, Woodville, South Australia
Royal Hobart Hospital, Hobart, Tasmania
Launceston General Hospital, Launceston, Tasmania
Ballarat Health Services, Ballarat Central, Victoria
Box Hill Hospital, Box Hill, Victoria
Monash Health, Clayton, Victoria
Barwon Health, Geelong, Victoria
St Vincent's Hospital, Melbourne, Victoria
Northern Hospital, Melbourne, Victoria
Maroondah Hospital, Melbourne, Victoria
Goulburn Valley Health, Shepparton, Victoria
Breast Cancer Research Centre-WA, Nedlands, Western Australia
Medizinische Universität Graz, Graz, Steiermark
Private Practice - Dr. Hubalek, Schwaz, Tirol
Universitaetsklinikum Allgemeines Krankenhaus Wien, Vienna, Wien
Klinik Hietzing, Vienna, Wien
Uniklinikum Salzburg, Salzburg, Not set
Medizinische Universität Wien, Wien, Not set
Institut Jules Bordet, Anderlecht, Bruxelles-Capitale, Région De
CHIREC - site delta, Auderghem, Bruxelles-Capitale, Région De
CHU Saint-Pierre, Brussels, Bruxelles-Capitale, Région De
Centre Hospitalier Universitaire Brugmann, Brussels, Bruxelles-Capitale, Région De
Cliniques universitaires Saint-Luc, Brussels, Bruxelles-Capitale, Région De
Grand Hôpital de Charleroi, Charleroi, Hainaut
Groupe Jolimont, La Louvière, Hainaut
Jessa Ziekenhuis, Hasselt, Limburg
AZ Nikolaas, Sint-Niklaas, Oost-Vlaanderen
UZ Leuven, Leuven, Vlaams-Brabant
AZ Groeninge Campus Kennedylaan, Kortrijk, West-Vlaanderen
AZ Oostende vzw, Oostende, West-Vlaanderen
Jan Yperman ziekenhuis, Ieper, Not set
Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman, Liège, Not set
CHU UCL Namur/Site Sainte Elisabeth, Namur, Not set
Clinique Saint Pierre, Ottignies, Not set
CHR Verviers - La Tourelle, Verviers, Not set
Nucleo de Oncologia da Bahia, Salvador, Bahia
Centro de Pesquisa Clínica do Instituto do Câncer do Ceará, Fortaleza, Ceará
CEDOES, Vitória, Espírito Santo
Hospital Araújo Jorge, Goiânia, Goiás
Oncocentro de Minas Gerais, Belo Horizonte, Minas Gerais
Centro Integrado de Oncologia de Curitiba, Curitiba, Paraná
Hospital de Cancer de Londrina, Londrina, Paraná
CTO - Centro de Tratamento Oncológico, Belem, Pará
Multihemo, Recife, Pernambuco
ONCOSITE - Centro de Pesquisa Clinica em Oncologia, Ijui, Rio Grande Do Sul
Hospital Moinhos de Vento, Porto Alegre, Rio Grande Do Sul
Centro Gaucho Integrado De Oncologia, Hematologia, Ensino E Pesquisa, Porto Alegre, Rio Grande Do Sul
Hospital São Lucas da PUCRS, Porto Alegre, Rio Grande Do Sul
Hospital de Amor Amazônia, Porto Velho, Rondônia
Fundação Pio XII - Hospital de Câncer de Barretos, Barretos, São Paulo
Hospital de Clínicas de Ribeirão Preto, Ribeirão Preto, São Paulo
Faculdade de Medicina do ABC, Santo André, São Paulo
Hospital Sírio Libanês, Sao Paulo, São Paulo
Hospital BP, Sao Paulo, São Paulo
A. C. Camargo Cancer Center, Sao Paulo, São Paulo
Instituto D'Or de Pesquisa e Ensino (IDOR), Sao Paulo, São Paulo
Hospital Santa Paula, Sao Paulo, São Paulo
Fundação Faculdade Regional de Medicina de São José do Rio Preto, São José do Rio Preto, São Paulo
Hospital Sirio Libanes, Brasilia, Not set
Instituto Nacional de Câncer - INCA, Rio de Janeiro, Not set
Hospital São Lucas de Copacabana, Rio de Janeiro, Not set
Centro de Tratamento de Tumores Botafogo para Oncoclinicas Rio de Janeiro SA, Rio de Janeiro, Not set
Instituto de Educação, Pesquisa e Gestão em Saúde, Rio de Janeiro, Not set
IPITEC, São Paulo, Not set
NotreDame Intermedica Saude S.A, São Paulo, Not set
Instituto de Ensino e Pesquisa São Lucas, São Paulo, Not set
Icesp - Instituto Do Câncer Do Estado de São Paulo, São Paulo, Not set
Clínica de Pesquisa e Centro de Estudos em Ginecologia Oncológica e Mamária LTDA, São Paulo, Not set
Hospital Alemao Oswaldo Cruz, São Paulo, Not set
Núcleo de Pesquisa Clínica da Rede São Camilo, São Paulo, Not set
Instituto de Assistência Médica ao Servidor Público Estadual - IAMSPE/HSPE-FMO Conhecer Centro de Oncolog -T, São Paulo, Not set
Arthur J.E. Child Comprehensive Cancer Centre, Calgary, Alberta
BC Cancer Surrey, Surrey, British Columbia
Victoria Hospital & Children's Hospital - London Health Sciences Centre, London, Ontario
Humber River Hospital, Toronto, Ontario
Sunnybrook Research Institute - Odette Cancer Centre, Toronto, Ontario
Jewish General Hospital, Montreal, Quebec
Centre intégré universitaire de santé et de services sociaux du Nord-de-l'Île-de-Montréal (CIUSSS NÎM) - H -T, Montreal, Quebec
Centre Hospitalier de l'Université de Montréal, Montréal, Quebec
CHU de Québec-Université Laval, Hôpital du Saint-Sacrement, Quebec City, Quebec
Wannan Medical College Yijishan Hospital, Wuhu Shi, Anhui
Beijing Hospital, Beijing, Beijing
Cancer Hospital Chinese Academy of Medical Science, Beijing, Beijing
Peking University People's Hospital, Beijing, Beijing
Beijing Friendship Hospital Affiliate of Capital University, Beijing, Beijing
Fujian Medical University Union Hospital-1 Bingfanglou, Fuzhou, Fujian
The 900th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Fuzhou, Fujian
Dongguan People's Hospital, Dongguan, Guangdong
Shunde Hospital of Southern Medical Univesity, Foshan, Guangdong
Sun Yat-sen University Cancer Center, Guangzhou, Guangdong
Guangdong Maternity and Child Health Care Hospital, Guangzhou, Guangdong
Huizhou Municipal Central Hospital, Huizhou, Guangdong
Jiangmen Center Hospital, Jiangmen, Guangdong
Cancer Hospital of Shantou University Medical College, Shantou, Guangdong
ShenZhen People's Hospital, Shenzhen, Guangdong
Shenzhen Second People's Hospital, Shenzhen, Guangdong
Cancer Hospital Chinese Academy of Medical Sciences. Shenzhen Center, Shenzhen, Guangdong
Central Hospital of Guangdong Provincial Agricutural Reclamation, Zhanjiang, Guangdong
Hainan General Hospital, Haikou, Hainan
Affiliated Hospital of Hebei University, Baoding, Hebei
Anyang Cancer Hospital, Anyang, Henan
The First Affiliated Hospital of Henan University of Science &Technology, Luoyang, Henan
Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei
Renmin Hospital of Wuhan University, Wuhan, Hubei
Hubei Cancer Hospital, Wuhan, Hubei
Xiangyang Central Hospital, Xiangyang, Hubei
The First People's Hospital of Changde City, Changde, Hunan
Xiangya Hospital Central South University, Changsha, Hunan
Hunan Cancer Hospital, Changsha, Hunan
The Central Hospital of Yongzhou - North Campus, Yongzhou, Hunan
The First People's Hospital of Yueyang, Yueyang, Hunan
First Huai'an Hospital Affiliated to Nanjing Medical University, Huai'an, Jiangsu
Jiangsu Province Hospital, Nanjing, Jiangsu
The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu
The Third Hospital of Nanchang, Nanchang, Jiangxi
The First Hospital of Jilin University, Changchun, Jilin
The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi
Jinan Central Hospital, Jinan, Shandong
Jining Medical University - Affiliated Hospital, Jining, Shandong
Fudan University Shanghai Cancer Center, Shanghai, Shanghai
Yuncheng Central Hospital - Eastern Hospital, Yuncheng Shi, Shanxi
Sichuan Cancer hospital, Chengdu, Sichuan
Deyang City People's Hospital, Deyang, Sichuan
The Second People's Hospital of Neijiang, Neijiang, Sichuan
Tianjin Medical University Cancer Institute & Hospital, Tianjing, Tianjin
Xinjiang Medical University Cancer Hospital - Urumqi, Urumqi, Xinjiang
The First People's Hospital of Hangzhou, Hangzhou, Zhejiang
Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang
Zhejiang Cancer Hospital, Hangzhou, Zhejiang
Hwa Mei Hospital University of Chinese Academy of Sciences, Ningbo, Zhejiang
Ningbo First Hospital, Ningbo, Zhejiang
Nemocnice Horovice, Horovice, Beroun
Masarykuv onkologicky ustav, Brno, Brno-město
Fakultni nemocnice Hradec Kralove, Hradec Kralove, Hradec Králové
Fakultni nemocnice Ostrava, Ostrava, Moravskoslezský Kraj
Multiscan, Pardubice, Pardubický Kraj
Fakultni Thomayerova nemocnice, Prague, Praha 4
Fakultni nemocnice Motol, Praha, Praha 5
Fakultni nemocnice Bulovka, Prague, Praha 8
Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest, Bordeaux, Aquitaine
Polyclinique De Blois, La Chaussée-Saint-Victor, Centre
Groupe Hospitalier La Rochelle-Ré-Aunis - Hôpital Saint Louis, La Rochelle, Charente-Maritime
CHU Besançon, Besançon, Doubs
CHRU de Brest, Brest, Finistère
Clinique Francois Chenieux, Limoges, Haute-Vienne
Institut Curie - site Saint-Cloud, Saint-Cloud, Hauts-de-Seine
Chu Grenoble Alpes, La Tronche, Isère
Centre Hospitalier Intercommunal de Mont-de-Marsan et du Pays des Sources, Mont-de-Marsan, Landes
Centre de Cancérologie du Grand Montpellier, Montpellier, Languedoc-Roussillon
Institut de Cancérologie de l'Ouest, Saint Herblain, Loire-Atlantique
Institut de Cancérologie de Lorraine Alexis Vautrin, Vandoeuvre-lès-Nancy, Lorraine
Institut Jean Godinot, Reims, Marne
Polyclinique de Gentilly, Nancy, Meurthe-et-Moselle
Centre Hospitalier Régional Metz Thionville - Hôpital de Mercy, Metz, Moselle
Clinique Victor Hugo Le Mans, Le Mans, Pays-de-la-Loire
Centre Hospitalier de la Côte Basque, Bayonne, Pyrénées-Atlantiques
Centre Hospitalier de Pau, Pau, Pyrénées-Atlantiques
Centre Catalan d'Oncologie, Perpignan, Pyrénées-Orientales
Hopital Prive Jean Mermoz, Lyon, Rhône-Alpes
Sainte Catherine Institut du Cancer Avignon Provence, Avignon, Vaucluse
CHD Vendee, La Roche-sur-Yon, Vendée
Centre Hospitalier Universitaire de Poitiers, Poitiers, Vienne
Pole Santé République, Clermont-Ferrand, Not set
Centre Antoine-Lacassagne, Nice, Not set
Hôpital Saint-Louis, Paris, Not set
Hôpital Européen Georges Pompidou, Paris, Not set
Groupe Hospitalier Diaconesses Croix Saint Simon, Paris, Not set
Institut Curie, Paris, Not set
Hôpital Tenon, Paris, Not set
Centre Hospitalier Privé Saint-Grégoire, Saint-Grégoire, Not set
Centre de cancérologie des Dentellières, Valenciennes, Not set
Henri Mondor Hospital, Créteil, Île-de-France
Groupe hospitalier Paris saint Joseph, Paris, Île-de-France
Universitaetsklinikum Freiburg, Freiburg im Breisgau, Baden-Württemberg
Private Practice - Dr. Helmut Oettle und Prof.Dr.med. Frank Mayer, Friedrichshafen, Baden-Württemberg
Universitätsmedizin Mannheim, Mannheim, Baden-Württemberg
Robert-Bosch-Krankenhaus, Stuttgart, Baden-Württemberg
Universitaetsklinikum Tuebingen, Tübingen, Baden-Württemberg
Universitaetsklinikum Ulm, Ulm, Baden-Württemberg
Gemeinschaftspraxis hop-augsburg, Augsburg, Bayern
Universitaetsklinikum Augsburg, Augsburg, Bayern
Onkologiezentrum Donauwörth, Donauwörth, Bayern
Universitaetsklinikum Erlangen, Erlangen, Bayern
Klinikverbund Allgäu gGmbH, Kempten, Bayern
Klinikum der Ludwig-Maximilians-Universitaet Muenchen, München, Bayern
Klinikum Ernst von Bergmann, Potsdam, Brandenburg
Agaplesion Markus Krankenhaus, Frankfurt, Hessen
Helios HSK Wiesbaden, Wiesbaden, Hessen
HELIOS Kliniken Schwerin, Schwerin, Mecklenburg-Vorpommern
Marienhospital Bottrop, Bottrop, Nordrhein-Westfalen
St.-Johannes-Hospital Dortmund, Dortmund, Nordrhein-Westfalen
MVZ Medical Center Düsseldorf GmbH, Düsseldorf, Nordrhein-Westfalen
Kliniken Essen-Mitte, Evangelische Huyssens-Stiftung, Essen, Nordrhein-Westfalen
St. Anna Hospital, Herne, Nordrhein-Westfalen
Zentrum fuer ambulante gynaekologische Onkologie (ZAGO), Krefeld, Nordrhein-Westfalen
Universitaetsklinikum Koeln, Köln, Nordrhein-Westfalen
Onkologisch-hämatologisches Forschungsinstitut am Habsburgring, Mayen, Rheinland-Pfalz
Klinikum Mutterhaus der Borromäerinnen, Trier, Rheinland-Pfalz
Universitaetsklinikum des Saarlandes, Homburg, Saarland
Städtisches Klinikum Dessau, Dessau, Sachsen-Anhalt
Universitaetsklinikum Schleswig-Holstein Campus Kiel, Kiel, Schleswig-Holstein
SRH Wald-Klinikum Gera, Gera, Thüringen
SRH Zentralklinikum Suhl, Suhl, Thüringen
Praxisklinik Krebsheilkunde fur Frauen, Berlin, Not set
Onkologische Schwerpunktpraxis Kurfuerstendamm, Berlin, Not set
Helios Klinikum Berlin-Buch, Berlin, Not set
OSP Göttingen, Goettingen, Not set
Olympion General Clinic, Patras, Achaḯa
University Hospital of Patras, Patras, Achaḯa
Iaso Private General Obstetrics Gynecological & Pediatric Clinic Diagnostic Therapeutic & Research Center -T, Athens, Attikí (Region)
Agios Savvas Regional Cancer Hospital, Athens, Attikí
Alexandra Hospital, Athens, Attikí
IASO Obstetrics - Gynecology Clinic, Athens, Attikí
Attikon General University Hospital, Chaidari, Attikí
General Oncology Hospital of Kifissia "Agioi Anargiroi", Nea Kifissia, Attikí
University Hospital of Ioannina, Ioannina, Ioánnina
University General Hospital of Heraklion, Heraklion, Irakleío
BioClinic Thessaloniki, Thessaloniki, Kentrikí Makedonía
Agios Loukas Clinic, Thessaloniki, Kentrikí Makedonía
Euromedica General Clinic of Thessaloniki, Thessaloniki, Thessaloníki
European Interbalkan Medical Center, Thessaloniki, Thessaloníki
University General Hospital of Larissa, Larissa, Thessalía
Queen Mary Hospital, Hksar, Not set
Bacs-Kiskun Megyei Korhaz, Kecskemét, Bács-Kiskun
Szabolcs Szatmár Bereg Vármegyei Oktatókórház, Nyiregyhaza, Szabolcs-Szatmár-Bereg
Országos Onkológiai Intézet, Budapest, Not set
Uzsoki Utcai Kórház, Budapest, Not set
Debreceni Egyetem Klinikai Kozpont, Debrecen, Not set
Mahatma Gandhi Cancer Hospital and Research Institute, Visakhapatnam, Andhra Pradesh
Delhi State Cancer Institute, New Delhi, Delhi
Hemato Oncology Clinic, Ahmedabad, Gujarat
KD Hospital, Ahmedabad, Gujarat
Medstar Speciality Hospital, Bangalore, Karnataka
KLES Dr. Prabhakar Kore Hospital & M.R.C, Belagavi, Karnataka
Regional Cancer Centre - Thiruvananthapuram, Thiruvananthapuram, Kerala
Krishna Institute of Medical Sciences - Karad, Karad, Maharashtra
Kolhapur Cancer Centre Private Limited, Kolhapur, Maharashtra
Tata Memorial Hospital, Mumbai, Maharashtra
Rashtrasant Tukdoji Regional Cancer Hospital, Nagpur, Maharashtra
Grant Medical Foundation - Ruby Hall Clinic, Pune, Maharashtra
Lifepoint Multispeciality Hospital, Pune, Maharashtra
All India Institute of Medical Sciences, Bhubaneswar, Odisha
Cancer Institute (WIA), Chennai, Tamil Nadu
Nizam's Institute of Medical Sciences, Hyderabad, Telangana
Regency Hospital, Kanpur, Uttar Pradesh
Postgraduate Institute of Medical Education & Research, Chandigarh, Not set
Galway University Hospital, Galway, Connaught
Bon Secours Cork Hospital, Cork, Not set
Cork University Hospital, Cork, Not set
St. Vincent's University Hospital, Dublin, Not set
St. James's Hospital, Dublin, Not set
UCD School of Medicine Beacon Hospital, Dublin, Not set
Beaumont Hospital, Dublin, Dublin, Not set
Sligo General Hospital, Sligo, Not set
Waterford Regional Hospital, Waterford, Not set
Meir Medical Center, Kfar Saba, HaMerkaz
Rabin Medical Center, Petah Tikva, HaMerkaz
Sheba Medical Center, Ramat Gan, HaMerkaz
Yitzhak Shamir Medical Center, Zerifin, HaMerkaz
Sourasky Medical Center, Tel Aviv, Tell Abīb
Shaare Zedek Medical Center, Jerusalem, Yerushalayim
Hadassah Medical Center, Jerusalem, Yerushalayim
Carmel Hospital, Haifa, Ḥeifā
University of Naples Federico II, Naples, Campania
Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania
Humanitas Istituto Clinico Catanese, Misterbianco, Catania
IRCCS - AOU di Bologna, Bologna, Emilia-Romagna
Ospedale San Martino, Genova, Liguria
Ospedale San Gerardo-ASST Monza, Monza, Lombardia
Humanitas, Rozzano, Milano
Istituto Nazionale Tumori Regina Elena, Rome, Roma
Ospedale San Giovanni Moscati, Statte, Taranto
Istituto di Candiolo IRCCS - Fondazione del Piemonte per l'Oncologia, Candiolo, Torino
Azienda Ospedaliera Universitaria Careggi, Firenze, Toscana
Aou Ospedali Riuniti Umberto I, Ancona, Not set
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Not set
Ospedale Antonio Perrino, Brindisi, Not set
Ospedale Generale Provinciale Macerata, Macerata, Not set
Istituto Europeo di Oncologia IRCCS, Milano, Not set
Azienda Ospedaliero Universitaria, Modena, Not set
Istituto Oncologico Veneto IRCCS, Padova, Not set
Azienda Ospedaliero Universitaria di Parma, Parma, Not set
Azienda Ospedaliera Santa Maria Terni, Terni, Not set
Nagoya University Hospital, Nagoya, Aichi
Nagoya City University Hospital, Nagoya, Aichi
Chiba cancer center, Chiba-shi, Chiba
Kameda Clinic, Kamogawa, Chiba
National Hospital Organization Shikoku Cancer Center, Matsuyama, Ehime
Gunma Prefectural Cancer Center, Otashi, Gunma
National Hospital Organization Takasaki General Medical Centar, Takasaki, Gunma
Fukuyama City Hospital, Fukuyama, Hiroshima
National Hospital Organization Hokkaido Cancer Center, Sapporo, Hokkaido
Hokkaido University Hospital, Sapporo, Hokkaido
Hyogo Medical University Hospital, Nishinomiya, Hyogo
Tsukuba University Hospital, Tsukuba, Ibaraki
Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa
Kanazawa Medical University Hospital, Uchinada, Ishikawa
Iwate Medical University Hospital, Yahaba-cho, Shiwa-gun, Iwate
St. Marianna University Hospital, Kawasaki, Kanagawa
Kitasato University Hospital, Sagamihara, Kanagawa
Yokohama City University Medical Center, Yokohama, Kanagawa
Kanagawa cancer center, Yokohama, Kanagawa
Tohoku University Hospital, Sendai-shi, Miyagi
Shinshu University Hospital, Matsumoto, Nagano
Niigata Cancer Center Hospital, Niigata-shi, Niigata
Naha Nishi Clinic, Naha, Okinawa
Kansai Medical University Hospital, Hirakata, Osaka
Shimane University Hospital, Izumo, Shimane
Tochigi Cancer Center, Utsunomiya, Tochigi
Juntendo University Hospital, Bunkyo-ku, Tokyo
St. Luke's International Hospital, Chuo-ku, Tokyo
Tokai University Hachioji Hospital, Hachioji-shi, Tokyo
Japanese Foundation for Cancer Research, Koto, Tokyo
Showa University Hospital, Shinagawa, Tokyo
National Center for Global Health and Medicine, Shinjyuku-ku, Tokyo
Chiba University Hospital, Chiba, Not set
National Hospital Organization Kyushu Cancer Center, Fukuoka, Not set
Fukushima Medical University, Fukushima, Not set
Gifu University Hospital, Gifu, Not set
Hiroshima City Hospital, Hiroshima, Not set
Hiroshima University Hospital, Hiroshima, Not set
Sagara Hospital, Kagoshima, Not set
Kumamoto Breast Surgical Hospital, Kumamoto, Not set
Kumamoto Shinto General Hospital, Kumamoto, Not set
University Hospital,Kyoto Prefectural University of Medicine, Kyoto, Not set
Kyoto University Hospital, Kyoto, Not set
Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Not set
Okayama University Hospital, Okayama, Not set
Nakagami Hospital Okinawa, Okinawa, Not set
National Hospital Organization - Osaka National Hospital - Institute For Clinical Research, Osaka, Not set
Saitama Red Cross Hospital, Saitama, Not set
Shizuoka General Hospital, Shizuoka, Not set
Tokushima University Hospital, Tokushima, Not set
Chungbuk National University Hospital, Cheongju-si, Chungcheongbuk-do [Chungbuk]
Soon Chun Hyang University Cheonan Hospital, Cheonan-si, Chungcheongnam-do [Chungnam]
Inha University Hospital, Incheon, Incheon-gwangyeoksi [Incheon]
Gachon University Gil Medical Center, Namdong-gu, Incheon-gwangyeoksi [Incheon]
Chonnam National University Hwasun Hospital, Hwasun-gun, Jeonranamdo
National Cancer Center, Goyang-si, Kyǒnggi-do
CHA Bundang Medical Center, CHA University, Seongnam-si, Kyǒnggi-do
Seoul National University Bundang Hospital, Seongnam, Kyǒnggi-do
Ajou University Hospital, Suwon-si, Kyǒnggi-do
Yeungnam Univeristy Medical Center, Gyeongsan-si, Kyǒngsangbuk-do
Dongnam Institute of Radiological and Medical Sciences, Busan, Pusan-Kwangyǒkshi
Korea University Anam Hospital, Seoul, Seoul-teukbyeolsi [Seoul]
Seoul National University Hospital, Seoul, Seoul-teukbyeolsi [Seoul]
Severance Hospital, Yonsei University Health System, Seoul, Seoul-teukbyeolsi [Seoul]
Asan Medical Center, Seoul, Seoul-teukbyeolsi [Seoul]
Gangnam Severance Hospital, Seoul, Seoul-teukbyeolsi [Seoul]
Samsung Medical Center, Seoul, Seoul-teukbyeolsi [Seoul]
The Catholic Univ. of Korea Seoul St. Mary's Hospital, Seoul, Seoul-teukbyeolsi [Seoul]
Korea University Guro Hospital, Seoul, Seoul-teukbyeolsi [Seoul]
Kyungpook National University Chilgok Hospital, Daegu, Taegu-Kwangyǒkshi
Ulsan University Hospital, Ulsan, Ulsan-Kwangyǒkshi
Hospital Angeles, Tijuana, Baja California
CENEIT Oncológicos. Centro Especializado en Investigación y Tratamientos Oncológicos, Mexico City, Distrito Federal
Grupo Medico Camino Sc, Mexico City, Distrito Federal
Preparaciones Oncologicas, León, Guanajuato
CIO - Centro de Inmuno-Oncología de Occidente, Guadalajara, Jalisco
Clinica de Investigacion en Reumatologia y Obesidad S. C., Guadalajara, Jalisco
Axis Heilsa S. de R.L. de C.V., Monterrey, Nuevo León
Centro Regiomontano de Investigación, Monterrey, Nuevo León
Filios Alta Medicina, Monterrey, Nuevo León
Centro Medico Zambrano Hellion, San Pedro Garza Garcia, Nuevo León
Oncologico Potosino, S.C., San Luis Potosi, San Luis Potosí
Centro de Estudios de Investigacion Metabolicos y Cardiovasculares, Ciudad Madero, Tamaulipas
Scientia Investigacion Clinica S.C., Chihuahua, Not set
Oaxaca Site Management Organization, Oaxaca, Not set
Centro de Investigacion Clinica de Oaxaca, Oaxaca, Not set
Unidad Médica Onco-hematológica, Puebla, Not set
PanAmerican Clinical Research - Querétaro - Avenida Antea, Querétaro, Not set
Centro Oncologico Estatal ISSEMyM ( COEI ), Toluca, Not set
Wilhelmina Ziekenhuis Assen, Assen, Drenthe
Maastricht UMC+, Maastricht, Limburg
VieCuri Medisch Centrum, locatie Venlo, Venlo, Limburg
Amphia Ziekenhuis, locatie Breda Molengracht, Breda, Noord-Brabant
Spaarne Gasthuis - Hoofddorp, Hoofddorp, Noord-Holland
Zaans Medisch Centrum, Zaandam, Noord-Holland
Deventer Ziekenhuis, Deventer, Overijssel
Ziekenhuisgroep Twente, locatie Almelo, Hengelo, Overijssel
Reinier de Graaf Ziekenhuis, locatie Delft, Delft, Zuid-Holland
Haga Ziekenhuis locatie Leyweg, Den Haag, Zuid-Holland
Albert Schweitzer Ziekenhuis, locatie Dordwijk, Dordrecht, Zuid-Holland
MICS Centrum Medyczne Torun, Torun, Kujawsko-pomorskie
Mazowiecki Szpital Wojewódzki w Siedlcach, Siedlce, Mazowieckie
Luxmed Onkologia sp. z o. o., Warszawa, Mazowieckie
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie, Warszawa, Mazowieckie
FORMED2, Oswiecim, Małopolskie
Opolskie Centrum Onkologii w Opolu im. prof. Tadeusza Koszarowskiego, Opole, Opolskie
Szpitale Pomorskie Sp. z o. o., Gdynia, Pomorskie
Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie, Koszalin, Zachodniopomorskie
Salve Medica, Lodz, Łódzkie
Champalimaud Foundation, Lisbon, Lisboa
Centro Hospitalar Universitário Lisboa Norte, E.P.E. - Hospital de Santa Maria, Lisbon, Lisboa
Centro Hospitalar de Vila Nova de Gaia/Espinho - Unidade I, Vila Nova de Gaia, Porto
Hopital Garcia de Orta, Almada, Setúbal
Hospital da Luz Lisboa, Lisboa, Not set
Hospital Beatriz Ângelo, Lisboa, Not set
C.M.D.T.A. Neomed, Brasov, Brașov
Onco Medint Srl, Bucharest, București
Lotus-Med, Bucharest, București
SC Memorial Healthcare International SRL, Bucharest, București
Institutul Oncologic Cluj, Cluj-Napoca, Cluj
Ovidius Clinical Hospital OCH, Ovidiu, Constanța
Centrul de Oncologie "Sfântul Nectarie", Craiova, Dolj
Radiology Therapeutic Center, Otopeni, Ilfov
S C Oncocenter Oncologie Clinica S R L, Timișoara, Timiș
Spitalul Clinic Colțea, București, Not set
Gral Medical Diagnostic Center, București, Not set
National Cancer Centre Singapore, Singapore, Central Singapore
Raffles Hospital, Singapore, Central Singapore
Onkologicky Ustav sv. Alzbety, Bratislava, Bratislavský Kraj
Narodny onkologicky ustav, Bratislava, Bratislavský Kraj
CHUAC-Hospital Teresa Herrera, A Coruña, A Coruña [La Coruña]
Hospital Universitario Torrecárdenas, Almeria, Andalucía
Hospital Universitari Son Espases, Palma, Balears [Baleares]
Parc de Salut Mar - Hospital del Mar, Barcelona, Barcelona [Barcelona]
Hospital Quiron Barcelona, Barcelona, Barcelona [Barcelona]
Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [Barcelona]
Hospital Universitari General de Catalunya, Sant Cugat del Vallès, Barcelona [Barcelona]
Hospital Universitari Dexeus, Barcelona, Catalunya [Cataluña]
Hospital Clínic de Barcelona, Barcelona, Catalunya [Cataluña]
Hospital de la Santa Creu i Sant Pau, Barcelona, Catalunya [Cataluña]
Hospital San Pedro de Alcántara, Cáceres, Extremadura
Complejo Hospitalario de Jaén, Jaen, Jaén
Hospital San Pedro, Logroño, La Rioja
Hospital Universitario Arnau de Vilanova de Lleida, Lleida, Lleida [Lérida]
Hospital Lucus Augusti, Lugo, Lugo [Lugo]
Hospital Universitario Getafe, Getafe, Madrid, Comunidad De
Hospital General Universitario Gregorio Marañon, Madrid, Madrid, Comunidad De
Hospital Universitario Infanta Leonor, Madrid, Madrid, Comunidad De
Hospital Universitario Ramón y Cajal, Madrid, Madrid, Comunidad De
Hospital Universitario 12 de Octubre, Madrid, Madrid, Comunidad De
Hospital Universitario La Paz, Madrid, Madrid, Comunidad De
Hospital Clínico Universitario Virgen de la Arrixaca, El Palmar, Murcia, Murcia, Región De
H.R.U Málaga - Hospital Materno-infantil, Malaga, Málaga
Complejo Hospitalario de Navarra, Pamplona, Navarra
Osi Bilbao-Basurto, Bilbao, País Vasco
Hospital Universitario de Canarias, La Laguna, Santa Cruz De Tenerife
Hospital Universitari Sant Joan de Reus, Reus, Tarragona [Tarragona]
Hospital Clinico de Valencia, Valencia, Valenciana, Comunitat
Hospital Quirónsalud Valencia, Valencia, València
Hospital General Universitario de Alicante, Alicante, Not set
Hospital Infanta Cristina, Badajoz, Not set
Hospital Universitario de Burgos, Burgos, Not set
Hospital Universitario San Cecilio, Granada, Not set
Hospital La Princesa, Madrid, Not set
Hospital Beata María Ana, Madrid, Not set
Hospital Ruber Internacional, Madrid, Not set
Hospital Clinico San Carlos, Madrid, Not set
Hospital Vithas Málaga, Málaga, Not set
Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Not set
Hospital Universitario Virgen Macarena, Sevilla, Not set
Hospital Universitario Virgen Del Rocio, Sevilla, Not set
Hospital Universitario de Toledo, Toledo, Not set
Hospital Clínico Universitario de Valladolid, Valladolid, Not set
Hospital Clínico Universitario Lozano Blesa, Zaragoza, Not set
Changhua Christian Hospital, Changhua County, Changhua
Chi Mei Hospital - Liouying Branch, Tainan City, Tainan
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Not set
Taipei Tzu Chi General Hospital, New Taipei City, Not set
Taichung Veterans General Hospital, Taichung, Not set
National Cheng Kung University Hospital, Tainan, Not set
National Taiwan University Hospital, Taipei, Not set
Mackay Memorial Hospital, Taipei, Not set
Taipei Veterans General Hospital, Taipei, Not set
Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Not set
Chang Gung Medical Foundation-Linkou Branch, Taoyuan, Not set
Hacettepe Universitesi, Altindağ, Ankara
Marmara Universitesi Pendik Egitim Arastirma Hastanesi, Istanbul, Pendik, İstanbul
Medipol Mega Universite Hastanesi, Stanbul, İstanbul
Izmir Medical Park Hospital, Izmir, Karsiyaka, İzmir
Mugla Sitki Kocman Universitesi Egitim ve Arastirma Hastanesi, Mugla, Muğla
Sakarya Training and Research Hospital, Adapazarı, Sakarya
Adana Medical Park Seyhan Hastanesi, Adana, Not set
Adana City Hospital, Adana, Not set
Ankara Gülhane Eitim ve Aratrma Hastanesi, Ankara, Not set
Ankara Etlik City Hospital, Ankara, Not set
Memorial Ankara Hastanesi, Ankara, Not set
Ankara Bilkent Şehir Hastanesi, Ankara, Not set
Akdeniz Universitesi Hastanesi, Antalya, Not set
Antalya Egitim ve Arastırma Hastanesi, Antalya, Not set
Uludag Universitesi, Bursa, Not set
Dicle Üniversitesi, Diyarbakir, Not set
Trakya University Medical Faculty Hospital, Edirne, Not set
Gaziantep Universitesi Sahinbey Arastirma ve Uygulama Hastanesi, Gaziantep, Not set
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi, Istanbul, Not set
Ege Universitesi Hastanesi, Izmir, Not set
zmir Katip Çelebi Üniversitesi Atatürk Eitim Ve Aratrma Hastanesi, Izmir, Not set
Kocaeli Üniversitesi, Kocaeli, Not set
İnönü Üniversitesi Turgut Özal Tıp Merkezi Eğitim ve Araştırma Hastanesi, Malatya, Not set
Mersin University, Mersin, Not set
Ondokuz Mayıs Universitesi, Samsun, Not set
Derriford Hospital, Plymouth, Devon
Panthera Biopartners - Preston, Preston, England
Colchester General Hospital, Colchester, Essex
Hairmyres Hospital, East Kilbride, Glasgow, Great Britain
Mount Vernon Hospital, Northwood, Hertfordshire
Lister Hospital, Stevenage, Hertfordshire
St Bartholomew's Hospital, London, London, City Of
Panthera Biopartners - Manchester, Rochdale, Manchester
Oncology Research, Wigan, Manchester
Western General Hospital, Edinburgh, Midlothian
Clatterbridge Cancer Centre - Liverpool, Liverpool, Not set
The Christie NHS Foundation Trust, Manchester, Not set
Royal Berkshire Hospital, Reading, Not set
Conditions: Breast Neoplasms
Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)
Recruiting
Researchers want to learn if patritumab deruxtecan (MK-1022) can treat certain breast cancers. The breast cancers being studied are HER2 positive unresectable locally advanced or metastatic (the cancer has spread to other parts of the body). The goals of this study are to learn:
* About the safety and how well people tolerate of patritumab deruxtecan
* How many people have the cancer respond (get smaller or go away) to treatment
Researchers want to learn if patritumab deruxtecan (MK-1022) can treat certain breast cancers. The breast cancers being studied are HER2 positive unresectable locally advanced or metastatic (the cancer has spread to other parts of the body). The goals of this study are to learn:
* About the safety and how well people tolerate of patritumab deruxtecan
* How many people have the cancer respond (get smaller or go away) to treatment Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/18/2025
Locations: Dana-Farber Cancer Institute ( Site 0050), Boston, Massachusetts +10 locations
Dana-Farber Cancer Institute ( Site 0050), Boston, Massachusetts
Rutgers Cancer Institute of New Jersey ( Site 0052), New Brunswick, New Jersey
Prisma Health - Upstate (ITOR)_Edenfield ( Site 0053), Greenville, South Carolina
Rambam Health Care Campus ( Site 0011), Haifa, Not set
Rabin Medical Center ( Site 0012), Petah Tikva, Not set
Sheba Medical Center ( Site 0010), Ramat Gan, Not set
Nagoya City University Hospital ( Site 0020), Nagoya, Aichi
Seoul National University Hospital ( Site 0030), Seoul, Not set
Asan Medical Center ( Site 0031), Seoul, Not set
University College London Hospital ( Site 0041), London, Camden
St Bartholomew s Hospital ( Site 0040), London, London, City Of
Conditions: Breast Neoplasms, Breast Cancer
Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
Recruiting
This is a Phase 1/2A, open label, multicenter, nonrandomized, multiple dose, safety, tolerability, pharmacokinetic and pharmacodynamic study of PF-07220060 administered as a single agent and then in combination with endocrine therapy.
The study consists of two parts and a China and Japan monotherapy cohort. Part 1 includes dose escalation cohorts evaluating PF-07220060 as single agent or in combination with endocrine therapy or enzalutamide, as well as a food effect cohort and a DDI cohort Part... Read More
This is a Phase 1/2A, open label, multicenter, nonrandomized, multiple dose, safety, tolerability, pharmacokinetic and pharmacodynamic study of PF-07220060 administered as a single agent and then in combination with endocrine therapy.
The study consists of two parts and a China and Japan monotherapy cohort. Part 1 includes dose escalation cohorts evaluating PF-07220060 as single agent or in combination with endocrine therapy or enzalutamide, as well as a food effect cohort and a DDI cohort Part 2 includes dose expansion cohorts evaluating PF-07220060 in combination with endocrine therapy or enzalutamide.
In Part 1A, single escalating doses of PF-07220060 alone will be administered to determine the maximum tolerated dose (MTD) and select the recommended dose for expansion In Part 1B and Part 1C, PF-07220060 will be administered in combination with 1 of 2 endocrine therapies (letrozole and fulvestrant, respectively).
In Part 1D, food effect assessment of PF-07220060 at the RP2D dose level from the Part 1A will be conducted In Part 1E, the effect of PF-07220060 on the PK of midazolam will be evaluated (DDI) In Part 1F, escalating dosed of PF-07220060 will be administered in combination with enzalutamide Part 1B and Part 1C may commence at MTD or before reaching the MTD at a dose level in Part 1A.
Part 2A is a dose expansion cohort with fulvestrant and will explore more than one dose of PF-07220060 in participants diagnosed with mBC.
Part 2B and Part 2C are expansion for combination therapy of PF-07220060 with letrozole and fulvestrant, respectively.
Part 2D is the expansion cohort for combination therapy of PF-07220060 with enzalutamide.
Part 2E is an expansion cohort to evaluate PF-07220060 Monotherapy versus PF-07220060 plus fulvestrant combination therapy. The China monotherapy cohort will evaluate safety, tolerability and PK of PF-07220060 administered as single agent in Chinese participants.
The Japan monotherapy cohort will evaluate safety, tolerability and PK of PF-07220060 administered as a single agent in Japanese participants. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/02/2025
Locations: Ellison Institute, Los Angeles, California +37 locations
Ellison Institute, Los Angeles, California
Smilow Cancer Hospital at Yale - New Haven, New Haven, Connecticut
Yale-New Haven Hospital-Yale Cancer Center, New Haven, Connecticut
Smilow Cancer Hospital Phase 1 Unit, New Haven, Connecticut
Brigham & Women's Hospital, Boston, Massachusetts
Dana-Farber Cancer Institute, Boston, Massachusetts
Dana Farber Cancer Institute- Chestnut Hill, Newton, Massachusetts
START Midwest, Grand Rapids, Michigan
Sarah Cannon Research Institute - Pharmacy, Nashville, Tennessee
SCRI Oncology Partners, Nashville, Tennessee
The University of Texas MD Anderson Cancer Center, Houston, Texas
Hospital Británico de Buenos Aires, Ciudad autónoma de Buenos Aires, Buenos Aires
Fundación Cenit Para La Investigación En Neurociencias, Caba, Ciudad Autã³noma DE Buenos Aires
Fundación Respirar, Buenos Aires, Not set
Clínica Universitaria Reina Fabiola, Córdoba, Not set
Fundación CORI para la Investigación y Prevención del Cáncer, La Rioja, Not set
Cancer Hospital Chinese Academy of Medical Science, Beijing, Beijing
Henan Cancer Hospital, Zhengzhou, Henan
Hubei Cancer Hospital, Wuhan, Hubei
The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shanxi
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang
Fakultni nemocnice Olomouc, Olomouc, Not set
Vseobecna fakultni nemocnice v Praze, Praha 2, Not set
National Cancer Center Hospital East, Kashiwa, Chiba
INCAN, Cdmx, Distrito Federal
Hospital MAC Periferico Sur, Ciudad de Mexico, Distrito Federal
COI Centro Oncologico Internacional S.A.P.I. de C.V., Mexico City, Distrito Federal
Hospital Universitario "Dr. Jose Eleuterio Gonzalez", Monterrey, Nuevo LEÓN
Hospital Reforma, Oaxaca de Juárez, Oaxaca
Oaxaca Site Management Organization, Oaxaca, Not set
Onkologicky ustav sv. Alzbety, s.r.o., Interna klinika VSZaSP a OUSA, Bratislava, Not set
Narodny onkologicky ustav, Bratislava, Not set
Fakultna nemocnica s poliklinikou Nove Zamky, Nove Zamky, Not set
POKO Poprad, s.r.o., Poprad, Not set
Cancer Research UK Edinburgh Centre, Edinburgh, Edinburgh, CITY OF
St Bartholomew's Hospital, London, London, CITY OF
Sarah Cannon Research Institute UK, London, Not set
The Christie Hospital NHS Foundation Trust, Manchester, Not set
PARTial BREast RECONstruction With Chest Wall Perforator Flap
Recruiting
The goal of this observational study is to ascertain the outcomes following partial breast reconstruction using chest wall perforator flaps after breast conservation surgery.
The goal of this observational study is to ascertain the outcomes following partial breast reconstruction using chest wall perforator flaps after breast conservation surgery. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/07/2024
Locations: Cambridge University Hospitals NHS Trust, Cambridge, Cambridgeshire
Cambridge University Hospitals NHS Trust, Cambridge, Cambridgeshire
Conditions: Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Carcinoma, Breast Neoplasms, Breast Surgery, Breast Reconstruction Surgery
Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies
Recruiting
This study is a Phase I/II, multicenter, first-in-human, open-label dose-escalation study of BT8009 given as a single agent and in combination with pembrolizumab in participants with advanced solid tumors associated with Nectin-4 expression or in participants with advanced solid tumor malignancies having renal insufficiency. The primary endpoints are: Dose limiting toxicities (Parts A-1 and A-2), Overall response rate per RECIST v1.1 (Parts B1-B7), Safety and tolerability (Parts B-8, B-9 and C),... Read More
This study is a Phase I/II, multicenter, first-in-human, open-label dose-escalation study of BT8009 given as a single agent and in combination with pembrolizumab in participants with advanced solid tumors associated with Nectin-4 expression or in participants with advanced solid tumor malignancies having renal insufficiency. The primary endpoints are: Dose limiting toxicities (Parts A-1 and A-2), Overall response rate per RECIST v1.1 (Parts B1-B7), Safety and tolerability (Parts B-8, B-9 and C), and characterization of the pharmacokinetics (Part D). Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: Sarah Cannon Research Institute at HealthONE, Denver, Colorado +28 locations
Sarah Cannon Research Institute at HealthONE, Denver, Colorado
Ocala Oncology Center, Ocala, Florida
Advent Health, Orlando, Florida
Horizon Oncology Research, Lafayette, Indiana
Norton Cancer Institute, Downtown, Louisville, Kentucky
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada
Icahn School of Medicine at Mount Sinai, New York, New York
University Hospitals Cleveland Medical Center, Cleveland, Ohio
Thomas Jefferson University, Sidney Kimmel Cancer Center, Philadelphia, Pennsylvania
Tennessee Oncology, PLLC, Nashville, Tennessee
Mary Crowley Cancer Research Center, Dallas, Texas
The University of Texas MD Anderson Cancer Center, Houston, Texas
Cross Cancer Institute, Edmonton, Alberta
University Health Network, Princess Margaret Cancer Centre, Toronto, Ontario
Institut Bergonie, Bordeaux, Not set
Centre Leon Berard, Lyon, Not set
Institut Paoli-Calmettes, Marseille, Not set
Centre Eugene Marquis, Rennes, Not set
Institut Gustave Roussy, Villejuif, Not set
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, MI
Ospedale San Raffaele, Milan, Not set
Vall d'Hebron Institute of Oncology, Barcelona, Not set
Hospital Clinic de Barcelona, Barcelona, Not set
START Madrid Fundacion Jimenez Diaz, Madrid, Not set
Hospital Universitario La Paz, Madrid, Not set
Next Oncology - Hospital Quironsalud Madrid, Pozuelo de Alarcon, Not set
Hospital Universitario Marques de Valdecilla, Santander, Not set
Sarah Cannon Research Institute UK, London, Not set
The Christie NHS Foundation Trust, Manchester, Not set
Conditions: Advanced Solid Tumor, Urinary Bladder Neoplasm, Triple Negative Breast Neoplasms, Ovarian Neoplasm, Hormone Receptor Positive, HER2-negative Neoplasms, Hormone Receptor Positive, HER2-low Neoplasms, Breast Neoplasms, Non-Small-Cell Lung Neoplasms
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