There are currently 4 active clinical trials seeking participants for Huntington Disease research studies. The states with the highest number of trials for Huntington Disease participants are .
Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers
NCT06667414
Recruiting
For participation in this epidemiological study, a single-day visit at the study site is required. Participants will be recruited from Huntington Disease clinics, and they will be asked to answer questions regarding their demographics, including sex, age, race and ethnicity, and their medical and medication history. At the end of the visit, a blood sample will be drawn to allow testing with a sequencing assay that is specifically designed for phasing single nucleotide polymorphisms (SNPs) on the... Read More
Gender:
ALL
Ages:
Between 25 years and 60 years
Trial Updated:
08/12/2025
Locations: Uab Medicine, Birmingham, Alabama +40 locations
Conditions: Huntington Disease
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IMarkHD: in Vivo Longitudinal Imaging of HD Pathology
NCT03434548
Recruiting
iMarkHD is an adaptive, longitudinal positron emission tomography (PET) and magnetic resonance (MR) imaging study in Huntington's disease (HD) that aims to assess abnormal molecular, functional, and structural changes in participants' brains, ranging from several years before symptom onset to the advanced symptom stage. The study will be conducted over a three (3) year period (Baseline, Year-1, and Year-2).
Gender:
ALL
Ages:
Between 21 years and 75 years
Trial Updated:
03/03/2025
Locations: King's College London, London, England
Conditions: Huntington Disease
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A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD
NCT05822908
Recruiting
The goal of this first-in-human clinical trial is to assess the safety and tolerability of four doses of a new study drug called VO659 in people with genetic disorders called spinocerebellar ataxia type 1, type 3 or Huntington's disease. Another aim is to determine the concentrations of the study drug in the cerebral spinal fluid and blood after single and multiple doses. Study drug will be administered by lumbar intrathecal bolus injections.
Gender:
ALL
Ages:
Between 25 years and 60 years
Trial Updated:
04/05/2024
Locations: Rigshospitalet, Kopenhagen, Not set +14 locations
Conditions: Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 3, Huntington Disease
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Benchmarking Integrated Care for People Living With Huntington's Disease in England
NCT05828992
Recruiting
The survey and full study information can be accessed here: https://southampton.qualtrics.com/jfe/form/SV_8iEedDJZy4xaiI6 The goal of this anonymous survey is to benchmark integrated care from the perspective of service users in adults living with Huntington's Disease, including informal caregivers. The main question it aims to answer is: Is standard of care for people living with HD in England person-centred integrated care from the perspective of service users? Participants will complete a o... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/18/2023
Locations: University of Southampton, Southampton, Hampshire
Conditions: Huntington Disease
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