Small Cell Lung Cancer Clinical Trials in United Kingdom

A listing of 4 Small Cell Lung Cancer clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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There are currently 4 active clinical trials seeking participants for Small Cell Lung Cancer research studies. The states with the highest number of trials for Small Cell Lung Cancer participants are .

Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)

NCT06117774

Recruiting

The primary objective of this study is to compare the efficacy of tarlatamab with placebo as assessed by progression free survival (PFS).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/13/2025

Locations: Valkyrie Clinical Trials, Los Angeles, California +202 locations

Valkyrie Clinical Trials, Los Angeles, California

University of California Los Angeles, Santa Monica, California

Yale New Haven Hospital, New Haven, Connecticut

Boca Raton Clinical Research Global South Florida, Plantation, Florida

University of Louisville James Graham Brown Cancer Center, Louisville, Kentucky

Our Lady of the Lake Cancer Institute, Baton Rouge, Louisiana

Morristown Medical Center, Morristown, New Jersey

Montefiore Einstein Center for Cancer Care, Bronx, New York

New York University Grossman School of Medicine and New York University Langone Hospitals, New York, New York

Perlmutter Cancer Center at New York University Langone Hospital - Long Island, New York, New York

FirstHealth Cancer Center, Pinehurst, North Carolina

Lehigh Valley Health Network, Allentown, Pennsylvania

Spokenword Clinical Trials, Easton, Pennsylvania

Renovatio Clinical, The Woodlands, Texas

US Oncology Research Investigational Products Center, The Woodlands, Texas

University of Virginia Health System, Charlottesville, Virginia

Virginia Cancer Specialists, PC, Fairfax, Virginia

West Virginia University Health Sciences Center, Morgantown, West Virginia

Fundacion Respirar, Ciudad Autonoma de Buenos Aires, Buenos Aires

Hospital Italiano de La Plata, La Plata, Buenos Aires

Hospital Universitario Austral, Pilar, Buenos Aires

Instituto Oncologico de Cordoba Ionc Fundacion Richardet Longo, Cordoba, Córdoba

Hospital Aleman Buenos Aires, Caba, Distrito Federal

Clinica Viedma, Viedma, Río Negro

Sanatorio 9 de Julio Cice 9 de Julio, San Miguel de Tucuman, Tucuman

Instituto Argentino de Diagnóstico y Tratamiento, Buenos Aires, Not set

Port Macquarie Base Hospital, Port Macquarie, New South Wales

Westmead Hospital, Westmead, New South Wales

Flinders Medical Centre, Bedford Park, South Australia

Monash Medical Centre, Clayton, Victoria

Fiona Stanley Hospital, Murdoch, Western Australia

Medizinische Universitaet Graz, Graz, Not set

Universitaetsklinikum Allgemeines Krankenhaus Wien, Wien, Not set

Institut Jules Bordet, Brussels, Not set

Universitair Ziekenhuis Gent, Gent, Not set

Oncoclinicas Onco Vida Distrito Federal, Brasilia, Distrito Federal

Hospital Santa Rita, Vitoria, Espírito Santo

Liga Paranaense do Combate ao Cancer - Hospital Erasto Gaertner, Curitba, Paraná

Londrina Cancer Hospital, Londrina, Paraná

Liga Norte-Riograndense Contra O Cancer, Natal, Rio Grande Do Norte

Hospital das Clinicas de Porto Alegre, Porto Alegre, Rio Grande Do Sul

Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul, Porto Alegre, Rio Grande Do Sul

Cipo - Centro Integrado de Pesquisa em Oncologia, Porto Alegre, Rio Grande Do Sul

Centro de pesquisa em oncologia Hospital Ana Nery, Santa Cruz do Sul, Rio Grande Do Sul

Centro Catarinense de Pesquisa LTDA, Blumenau, Santa Catarina

Fundacao Pio 12 Hospital de Amor de Barretos, Barretos, São Paulo

Fundacao Amaral Carvalho, Jau, São Paulo

Cepho, Santo Andre, São Paulo

Instituto Dor de Pesquisa e Ensino, Rio de Janeiro, Not set

Instituto Cancer Sao Paulo Icesp, São Paulo, Not set

Multiprofile Hospital for Active Treatment - Uni Hospital OOD, Panagyurishte, Not set

Complex Oncology Center Plovdiv EOOD, Plovdiv, Not set

Complex Oncology Center Shumen EOOD, Shumen, Not set

University Multiprofile Hospital for Active Treatment Sofiamed OOD, Sofia, Not set

University Multiprofile Hospital for Active Treatment Tsaritsa Yoanna - ISUL EAD, Sofia, Not set

Military Medical Academy Multiprofile Hospital for Active Treatment - Sofia, Sofia, Not set

Multiprofile Hospital for Active Treatment Serdika EOOD, Sofia, Not set

Beijing Cancer Hospital, Beijing, Beijing

Chongqing University Cancer Hospital, Chongqing, Chongqing

Fujian Cancer Hospital, Fuzhou, Fujian

Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, Fujian

Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong

Henan Cancer Hospital, Zhengzhou, Henan

Tongji Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei

Renmin Hospital of Wuhan University, Wuhan, Hubei

Hubei Cancer Hospital, Wuhan, Hubei

Hunan Cancer Hospital, Changsha, Hunan

Northern Jiangsu Peoples hospital, Yangzhou, Jiangsu

Jiangxi Cancer hospital, Nanchang, Jiangxi

The First Bethune Hospital of Jilin University, Changchun, Jilin

Cancer Hospital of Shandong First Medical University, Jinan, Shandong

Qingdao Municipal Hospital, Qingdao, Shandong

Fudan University Shanghai Cancer Center, Shanghai, Shanghai

Shanxi Provincial Cancer Hospital, Taiyuan, Shanxi

Shanxi Bethune Hospital, Taiyuan, Shanxi

Tianjin Cancer Hospital, Tianjin, Tianjin

The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang

The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang

Ningbo Medical Center Lihuili Hospital, Ningbo, Zhejiang

Zhejiang Taizhou Hospital, Taizhou, Zhejiang

Centro de Tratamiento e Investigación sobre Cancer Luis Carlos Sarmiento Angulo Ctic, Bogota, Cundinamarca

Instituto Nacional de Cancerologia, Bogota, Cundinamarca

Instituto Medico de Alta Tecnologia sas - Imat sas, Monteria, Córdoba

Oncologos del Occidente SAS, Pereira, Risaralda

Fundacion cardiovascular de Colombia, Bucaramanga, Santander

Centre Hospitalier Régional Universitaire de Lille - Institut Coeur Poumon, Lille, Not set

Centre Hospitalier Universitaire Nord, Marseille Cedex 20, Not set

Centre Hospitalier Universitaire de Nice - Hopital Pasteur, Nice Cedex 01, Not set

Hopital Bichat Claude Bernard, Paris, Not set

Hopital Nord Ouest Villefranche sur Saone, Villefranche Sur Saone Cedex, Not set

Universitaetsklinikum Essen, Essen, Not set

Universitaetsmedizin Goettingen, Goettingen, Not set

Universitaetsklinikum Wuerzburg, Wuerzburg, Not set

Agios Savvas Anticancer Hospital, Athens, Not set

Henry Dunant Hospital Center, Athens, Not set

Sotiria General Hospital, Athens, Not set

Attikon University Hospital, Athens, Not set

Metropolitan Hospital, Athens, Not set

Saint Lukes Hospital SA, Thessaloniki, Not set

European Interbalkan Medical Center, Thessaloniki, Not set

Queen Mary Hospital, The University of Hong Kong, Hong Kong, Not set

Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories, Not set

Centro di Riferimento Oncologico di Aviano, Aviano PN, Not set

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Not set

IRCCS Istituto Oncologico Europeo, Milano, Not set

Azienda Ospedaliera Universitaria San Luigi Gonzaga, Orbassano, Not set

Istituto Oncologico Veneto IRCCS, Padova, Not set

Azienda Ospedaliera di Perugia Ospedale Santa Maria della Misericordia, Perugia, Not set

Azienda Ospedaliero Universitaria Pisana, Pisa, Not set

Azienda Unita Sanitaria Locale di Reggio Emilia Arcispedale Santa Maria Nuova, Reggio Emilia, Not set

IRCCS Istituto Clinico Humanitas, Rozzano MI, Not set

Ospedale San Giuseppe Moscati, Statte, Not set

National Hospital Organization Nagoya Medical Center, Nagoya-shi, Aichi

National Cancer Center Hospital East, Kashiwa-shi, Chiba

National Hospital Organization Shikoku Cancer Center, Matsuyama-shi, Ehime

Kurume University Hospital, Kurume-shi, Fukuoka

National Hospital Organization Hokkaido Cancer Center, Sapporo-shi, Hokkaido

Kanagawa Prefectural Hospital Organization Kanagawa Cancer Center, Yokohama-shi, Kanagawa

Sendai Kousei Hospital, Sendai-shi, Miyagi

Niigata Cancer Center Hospital, Niigata-shi, Niigata

Okayama University Hospital, Okayama-shi, Okayama

Kansai Medical University Hospital, Hirakata-shi, Osaka

Osaka International Cancer Institute, Osaka-shi, Osaka

Kindai University Hospital, Osakasayama-shi, Osaka

Saitama Medical University International Medical Center, Hidaka-Shi, Saitama

Saitama Cancer Center, Kitaadachi-gun, Saitama

Shizuoka Cancer Center, Sunto-gun, Shizuoka

Dokkyo Medical University Hospital, Shimotsuga-gun, Tochigi

Juntendo University Hospital, Bunkyo-ku, Tokyo

National Cancer Center Hospital, Chuo-ku, Tokyo

The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto-ku, Tokyo

Wakayama Medical University Hospital, Wakayama, Not set

Chungbuk National University Hospital, Cheongju Chungbuk, Not set

National Cancer Center, Goyang-si Gyeonggi-do, Not set

Gachon University Gil Hospital, Incheon, Not set

Gyeongsang National University Hospital, Jinju-si, Not set

Cha Bundang Medical Center, Cha University, Seongnam-si, Gyeonggi-do, Not set

Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Not set

Severance Hospital Yonsei University Health System, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Oncare, Ciudad de México, Distrito Federal

Centro Oncologico Personalizado, Cuauhtemoc, Distrito Federal

Oncocenter Clinica Integral Internacional de Oncologia, Puebla, Not set

Phylasis Clinicas Research Toluca, Toluca, Not set

Uniwersytecki Szpital Kliniczny w Bialymstoku, Bialystok, Not set

Centrum Pulmonologii i Torakochirurgii w Bystrej, Bystra, Not set

Uniwersyteckie Centrum Kliniczne, Gdansk, Not set

Uniwerystecki Szpital Kliniczny Nr 4 w Lublinie, Lublin, Not set

Wielkopolskie Centrum Pulmonologii i Torakochirurgii imienia Eugenii i Janusza Zeylandow, Poznan, Not set

Szpital Specjalistyczny w Prabutach Spolka z Ograniczoną Odpowiedzialnoscia, Prabuty, Not set

Wojewodzki Szpital im Sw Ojca Pio w Przemyslu, Przemysl, Not set

Narodowy Instytut Onkologii im Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy, Warszawa, Not set

Unidade Local de Saude de Braga, EPE, Braga, Not set

Hospital da Luz, SA, Lisboa, Not set

Hospital Cuf porto, Porto, Not set

Spitalul Clinic de Urgenta Prof Dr Agrippa Ionescu, Balotesti, Ilfov, Not set

Institutul Oncologic, Prof Dr Alexandru Trestioreanu, Bucuresti, Not set

Institutul Oncologic Prof Dr Ion Chiricuta Cluj-Napoca, Cluj Napoca, Not set

Centrul de Oncologie Sf Nectarie SRL, Craiova, Not set

Institutul Regional de Oncologie Iasi, Iasi, Not set

Spitalul Municipal Ploiesti, Ploiesti, Not set

SC Oncomed SRL, Timisoara, Not set

National Cancer Centre Singapore, Singapore, Not set

Icon - Mount Alvernia, Singapore, Not set

Hospital Regional Universitario de Malaga, Malaga, Andalucía

Hospital Universitario Virgen del Rocio, Sevilla, Andalucía

Hospital Clinico Universitario Lozano Blesa, Zaragoza, Aragón

Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, Canarias

Institut Catala d Oncologia Badalona Hospital Universitari Germans Trias i Pujol, Badalona, Cataluña

Hospital del Mar, Barcelona, Cataluña

Hospital Universitari Vall d Hebron, Barcelona, Cataluña

Hospital Clinic i Provincial de Barcelona, Barcelona, Cataluña

Hospital de la Santa Creu i Sant Pau, Barcelona, Cataluña

Instituto Valenciano de Oncologia, Valencia, Comunidad Valenciana

Hospital Clinico Universitario de Santiago, Santiago de Compostela, Galicia

Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Madrid

Clinica Universidad de Navarra, Pamplona, Navarra

Hospital General Universitario Gregorio Maranon, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Sahlgrenska Universitetssjukhuset, Goteborg, Not set

Norrlands Universitetssjukhus, Umea, Not set

Kantonsspital Baden, Baden, Not set

Universitaetsspital Basel, Basel, Not set

Ospedale Regionale di Bellinzona e Vali, Mendrisio, Not set

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Not set

National Taiwan University Hospital, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Ankara Etlik Sehir Hastanesi, Ankara, Not set

Memorial Ankara Hastanesi, Ankara, Not set

Gazi Universitesi Saglik Arastirma ve Uygulama Merkezi Gazi Hastanesi, Ankara, Not set

Ankara Bilkent Sehir Hastanesi, Ankara, Not set

Bagcilar Medipol Mega Universite Hastanesi, Istanbul, Not set

Goztepe Prof Dr Suleyman Yalcin Sehir Hastanesi, Istanbul, Not set

Marmara Universitesi Tip Fakultesi Hastanesi, Istanbul, Not set

Dr Suat Seren Gogus Hastaliklari ve Cerrahisi Egitim ve Arastirma Hastanesi, Izmir, Not set

Izmir Ekonomi Universitesi Medical Point Hastanesi, Izmir, Not set

Kocaeli Universitesi Tip Fakultesi Hastanesi, Kocaeli, Not set

Medical Park Seyhan Hastanesi, Mersin, Not set

Ondokuz Mayis Universitesi Tip Fakultesi Hastanesi, Samsun, Not set

Guys Hospital, London, Not set

Christie Hospital, Manchester, Not set

Conditions: Limited Stage Small Cell Lung Cancer, Small Cell Lung Cancer

Learn More ›

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

NCT06203210

Recruiting

This study was designed to compare the efficacy and safety of I-DXd with treatment of physician's choice in participants with relapsed small cell lung cancer (SCLC).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/06/2025

Locations: Highlands Oncology Group, Springdale, Arkansas +229 locations

Highlands Oncology Group, Springdale, Arkansas

Clinical Research Providence Medical Foundation, Fullerton, California

UCLA Hematology-Oncology, Los Angeles, California

UCSF Mission Bay Mission Hall, San Francisco, California

University of Miami Hospital and Clinics Sylvester Comprehensive Cancer Center, Miami, Florida

AdventHealth Orlando, Cancer Institute, Orlando, Florida

H. Lee Moffitt Cancer Center and Research Institute, Inc, Tampa, Florida

Rush University Medical Center, Chicago, Illinois

Baptist Health Lexington, Lexington, Kentucky

University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland

John Hopkins School of Medicine, Baltimore, Maryland

Dana-Farber Cancer Institute, Boston, Massachusetts

Henry Ford Health System, Detroit, Michigan

Mercy Clinic Oncology and Hematology Sindelar Cancer Center, Saint Louis, Missouri

University of Nebraska Medical Center, Omaha, Nebraska

Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

Astera Cancer Care, East Brunswick, New Jersey

Meridian Health Systems, Neptune, New Jersey

Montefiore Medical Center Prime, Bronx, New York

Clinical Research Alliance, Inc, Lake Success, New York

New York University Cancer Center - Laura and Isaac, New York, New York

Cleveland Clinic Mercy Hospital, Canton, Ohio

Oncology/Hematology Care Clinical Trials, Llc, Cincinnati, Ohio

Providence Portland Medical Center, Portland, Oregon

THE WEST CLINIC, PLLC dba West Cancer Center, Germantown, Tennessee

Houston Methodist Cancer Center, Houston, Texas

University of Texas Md Anderson Cancer Center, Houston, Texas

Texas Oncology, P.A. - Tyler, Tyler, Texas

Medical College of Wisconsin, Milwaukee, Wisconsin

Ballarat Base Hospital, Ballarat, Not set

Flinders Medical Centre (Fmc), Bedford Park, Not set

Chris O Brien Lifehouse, Camperdown, Not set

Sunshine Hospital, St Albans, Not set

St John of God Subiaco Hospital, Subiaco, Not set

Townsville Cancer Centre, Townsville, Not set

Princess Alexandra Hospital, Woolloongabba, Not set

Landeskrankenhaus Feldkirch, Feldkirch, Not set

Landesklinikum Krems, Krems, Not set

Kepler University Hospital, Linz, Not set

Wiener Gesundheitsverband Klinik Penzing, Wien, Not set

Klinik Floridsdorf, Wien, Not set

Cliniques Universitaires Saint-Luc, Bruxelles, Not set

UZA, Edegem, Not set

Jessa Ziekenhuis Hospital, Hasselt, Not set

Centre Hospitalier Universitaire de Liege, Liege, Not set

AZ DELTA, Roeselare, Not set

Chu Ucl Namur, Yvoir, Not set

Departmento de Pesquisa Clinica- Hospital de Amor de Barretos, Barretos, Not set

Cepon - Centro de Pesquisas Oncolăgicas de Santa Catarina, FlorianĂłpolis, Not set

Clínica de Neoplasias Litoral, ItajaĂ-, Not set

Hospital São Lucas Da Pucrs, Porto Alegre, Not set

Cepho Centro de Estudos E Pesquisas de Hematologia E Oncologia, Santo Andre, Not set

Fundacao Faculdade Regional de Medicina de Sao Jose Do Rio Preto, Sao Jose Rio Preto, Not set

ICESP Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira, São Paulo, Not set

Hospital Benefică Ncia Portuguesa de Să O Paulo, São Paulo, Not set

Hospital Alemão Oswaldo Cruz, São Paulo, Not set

Hospital Sirio-Libanes, SĂŁo Paulo, Not set

A. C. Camargo Cancer Center, SĂŁo Paulo, Not set

William Osler Health System - Brampton Civic Hospital, Brampton, Not set

Cross Cancer Institute, Edmonton, Not set

Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec City, Not set

Princess Margaret Cancer Center, Toronto, Not set

Cancercare Manitoba, Winnipeg, Not set

China-Japan Friendship Hospital, Beijing, Not set

Beijing Cancer Hospital, Beijing, Not set

Beijing Chest Hospital,Capital Medical University, Beijing, Not set

Jilin Province Tumor Hospital, Changchun, Not set

Hunan Cancer Hospital, Changsha, Not set

West China Hospital, Sichuan University, Chengdu Shi, Not set

Sichuan Cancer Hospital, Chengdu, Not set

Chongqing University Cancer Hospital, Chongqing, Not set

Harbin Medical University Cancer Hospital, Haerbin, Not set

The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Not set

Zhejiang Cancer Hospital, Hangzhou, Not set

The Second Affiliated Hospital of Nanchang University, Jiangxi, Not set

Shandong Cancer Hospital, Jinan, Not set

Linyi Cancer Hospital, Linyi, Not set

The Second Peoples Hospital of Neijiang, Neijiang, Not set

Yantai Yuhuangding Hospital, Shandong, Not set

Fudan University Shanghai Cancer Center, Shanghai, Not set

Liaoning Cancer Hospital & Institute, Shenyang, Not set

Tianjin Medical University Cancer Institute & Hospital, Tianjin, Not set

The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, Not set

Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Not set

Huazhong University of Science and Technology - Tongji Medical College - Tongji Hospital Tjh, Wuhan, Not set

Hubei Cancer Hospital, Wuhan, Not set

The First Affiliated Hospital of Xiân Jiaotong University, Xi'an, Not set

Xiangyang Central Hospital, Xiangyang, Not set

Henan Cancer Hospital, Zhengzhou, Not set

Krajska Nemocnice Liberec A.S., Liberec, Not set

Fakultni Nemocnice Olomouc, Olomouc, Not set

Fakultni Thomayerova Nemocnice, Praha 4, Not set

Institut Sainte Catherine, Avignon, Not set

Chu Bordeaux, Bordeaux cedex, Not set

Centre Hospitalier Intercommunal de Cră Teil, Creteil Cedex, Not set

Institut Cœur Poumon CHU de Lille, Lille, Not set

Chu Limoges - Hopital Du Cluzeau, Limoges cedex, Not set

Centre Léon Bérard, Lyon, Not set

Assistance Publique-Hă"Pitaux de Marseille, Marseille, Not set

Hopital Arnaud de Villeneuve, Montpellier cedex 05, Not set

Institut Régional Du Cancer de Montpellier, Montpellier, Not set

Ch de Mulhouse - Hă"Pital Emile Muller, Mulhouse Cedex, Not set

Institut Curie - Site de Paris, Paris Cedex 05, Not set

Hopital Tenon, Paris, Not set

Chu Rennes - Hopital Pontchaillou, Rennes cedex 09, Not set

Chu Nantes - Hă"Pital Guillaume Et Renă Laă<Nnec, Saint Herblain, Not set

Institut de Cancerologie de La Loire, Saint-Priest-En-Jarez, Not set

Hă"Pital Foch, Suresnes Cedex, Not set

Institut Gustave Roussy, Villejuif, Not set

Evangelische Lungenklinik Berlin, Berlin, Not set

Helios Klinikum Erfurt, Erfurt, Not set

Universtitaetsklinikum Essen, Essen, Not set

Universitaetsklinikum Frankfurt Goethe-Universitaet, Frankfurt am Main, Not set

Krankenhaus Nordwest Gmbh, Frankfurt, Not set

Asklepios Fachkliniken Muenchen-Gauting, Gauting, Not set

Srh Wald-Klinikum Gera Gmbh, Gera, Not set

UNIVERSITATSKLINIKUM GIeBEN UND MARBURG GMBH, Giessen, Not set

Asklepios Klinik Harburg, Hamburg, Not set

Lki Lungenfachklinik Immenhausen, Immenhausen/Krs. Kassel, Not set

Staedtisches Krankenhaus Kiel, Kiel, Not set

Johannes Wesling Klinikum Minden, Minden, Not set

Pius-Hospital Oldenburg, Oldenburg, Not set

Universitaetsklinikum Ulm, Ulm, Not set

'Henry Dynant' Hospital Center, Athens, Not set

General Hospital of Athens of Chest Diseases 'Sotiria', Athens, Not set

General Hospital of Athens Alexandra, Athens, Not set

University General Hospital "Attikon", Chaidari, Not set

University General Hospital of Larissa, Larisa, Not set

General Hospital of Patra Agios Andreas, Patra, Not set

Metropolitan Hospital, Piraeus, Not set

St Luke'S Hospital, Thessaloniki, Not set

Semmelweis Egyetem, Budapest, Not set

Orszagos Koranyi Pulmonologiai Intezet, Budapest, Not set

Orszagos Onkologiai Intezet, Budapest, Not set

Gyor-Moson-Sopron Varmegyei Petz Aladar Egyetemi Oktato Korhaz, Gyor, Not set

Bács-Kiskun Vármegyei Oktatókórház, Kecskemet, Not set

Istituto Tumori Giovanni Paolo Ii Irccs Ospedale Oncologico Bari, Bari, Not set

Humanitas Gavazzeni, Bergamo, Not set

Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia (Presidio Spedali Civili), Brescia, Not set

Azienda Ospedaliera Universitaria Policlinico - Vittorio Emanuele (Presidio Gaspare Rodolico), Catania, Not set

Azienda Ospedaliero Universitaria Renato Dulbecco, Catanzaro, Not set

Istituto Nazionale Per La Ricerca Sul Cancro Di Genova, Genova, Not set

Ospedale San Raffaele, Milano, Not set

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Not set

IEO Istituto Europeo di Oncologia, Milano, Not set

Azienda Socio Sanitaria Territoriale Di Monza (Presidio San Gerardo), Monza, Not set

Azienda Ospedaliera Universitaria- Universită Degli Studi Della Campania Â Luigi Vanvitelliâ, Napoli, Not set

Azienda Ospedaliero Universitaria Di Parma, Parma, Not set

Azienda Ospedaliera Di Perugia Ospedale S. Maria Della Misericordia, Perugia, Not set

Istituto Nazionale Tumori Regina Elena Irccs, Roma, Not set

Istituto Clinico Humanitas, Rozzano, Not set

Centro Ricerche Cliniche Di Verona S.R.L., Verona, Not set

National Cancer Center Hospital, Chuo-ku, Not set

Kyushu University Hospital, Fukuoka, Not set

Kansai Medical University Hospital, Hirakata-shi, Not set

National Cancer Center Hospital East, Kashiwa, Not set

The Cancer Institute Hospital of Jfcr, Koto-ku, Not set

National Hospital Organization Shikoku Cancer Center, Matsuyama, Not set

Okayama University Hospital, Okayama, Not set

Kindai University Hospital, Osaka-Sayama, Not set

Kitasato University Hospital, Sagamihara, Not set

National Hospital Organization Hokkaido Cancer Center, Sapporo, Not set

Shizuoka Cancer Center, Sunto-gun, Not set

Osaka Medical and Pharmaceutical University Hospital, Takatsuki, Not set

Wakayama Medical University Hospital, Wakayama, Not set

Chungbuk National University Hospital, Cheongju, Not set

Kyungpook National University Chilgok Hospital, Daegu, Not set

Seoul National University Bundang Hospital, Seongnam-si, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

The Catholic University of Korea, St. Vincent'S Hospital, Suwon-si, Not set

Ajou University Hospital, Suwon, Not set

Netherlands Cancer Institute, Amsterdam, Not set

Maastricht University Medical Center, Maastricht, Not set

Jeroen Bosch Ziekenhuis, s Hertogenbosch, Not set

Etz Elisabeth, Tilburg, Not set

Centrum Onkologii Im. Prof. F. Lukaszczyka W Bydgoszczy, Bydgoszcz, Not set

Instytut Centrum Zdrowia Matki Polki, Lodz, Not set

Mazowieckie Centrum Leczenia Chorob Pluc I Gruzlicy, Otwock, Not set

Szpital Specjalistyczny W Prabutach, Prabuty, Not set

Provita Prolife, Tomaszow Mazowiecki, Not set

Centro Hospitalar E Universită Rio de Coimbra E.P.E., Coimbra, Not set

Hospital Da Senhora Da Oliveira Guimară Es, Guimarães, Not set

Hospital Da Luz, Lisboa, Not set

Centro Hospitalar de Lisboa Norte, E.P.E. - Hospital Pulido Valente, Lisboa, Not set

Centro Hospitalar Do Porto, E.P.E. - Hospital de Santo António, Porto, Not set

Institutul Oncologic 'Prof. Dr. Ion Chiricuta' Cluj Napoca, Cluj Napoca, Not set

S.C Radiotherapy Center Cluj S.R.L, Comuna Floresti, Not set

S.C Centrul de Oncologie Sfantul Nectarie Craiova, Craiova, Not set

S.C. Sigmedical Services Srl, Suceava, Not set

Hospital Clinic de Barcelona, Barcelona, Not set

Hospital de La Santa Creu I Sant Pau, Barcelona, Not set

Hospital Universitari Vall D'Hebron, Barcelona, Not set

Hospital Universitario Reina Sofia, Cordoba, Not set

Hospital Universitario Ciudad de Jaen, Jaen, Not set

Hospital de Especialidades de Jerez de La Frontera, Jerez De Frontera, Not set

Ico L'Hospitalet - Hospital Duran I Reynals, L'Hospitalet de Llobregat, Not set

Complejo Hospitalario Universitario Insular Materno-Infantil, Las Palmas de Gran Canaria, Not set

Hospital General Universitario Gregorio Marañon, Madrid, Not set

Hospital Universitario Ramon Y Cajal, Madrid, Not set

Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Regional Universitario de Malaga, Malaga, Not set

Hospital Universitario Virgen Macarena, Sevilla, Not set

Hospital Universitario Virgen Del Rocio, Sevilla, Not set

Hospital Universitario Nuestra Señora de Valme, Sevilla, Not set

Inselspital - Universitaetsspital Bern, Bern, Not set

Kantonsspital St. Gallen, St. Gallen, Not set

Hfr Fribourg/Kantonsspital Fribourg, Villars-sur-Glâne, Not set

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City, Not set

China Medical University Hospital, Taichung, Not set

Taichung Veterans General Hospital, Taichung, Not set

National Cheng Kung University Hospitalx, Tainan, Not set

National Taiwan University Cancer Centre, Taipei, Not set

Taipei Medical University Hospital, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Chang Gung Memorial Hospital, Taoyuan County, Not set

Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Not set

Ankara Bilkent City Hospital, Ankara, Not set

Dicle University, Medical Faculty, Diyarbakir, Not set

Goztepe Prof Dr Suleyman Yalcin City Hospital, Istanbul, Not set

Istanbul University Cerrahpasa - Cerrahpasa Medical Faculty, Istanbul, Not set

Medipol University Medical Faculty, Istanbul, Not set

Izmir Medicalpark Hospital, Izmir, Not set

Birmingham Heartlands Hospital, Birmingham, Not set

St James'S University Hospital, Leeds, Not set

Churchill Hospital, Oxford, Not set

Conditions: Small Cell Lung Cancer

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT04585750

Recruiting

The Phase 2 monotherapy portion of this study is currently enrolling and will evaluate the efficacy and safety of PC14586 (INN rezatapopt) in participants with locally advanced or metastatic solid tumors harboring a TP53 Y220C mutation. The Phase 1 portion of the study will assess the safety, tolerability and preliminary efficacy of multiple dose levels of rezatapopt as monotherapy and in Phase 1b in combination with pembrolizumab.

Gender:

ALL

Ages:

12 years and above

Trial Updated:

08/04/2025

Locations: Hoag Cancer Center, Irvine, California +80 locations

Hoag Cancer Center, Irvine, California

University of California Irvine Chao Family Comprehensive Cancer Center, Irvine, California

UCLA Jonsson Comprehensive Cancer Center, Los Angeles, California

USC Norris Comprehensive Cancer Center, Los Angeles, California

University of San Francisco, San Francisco, California

Rocky Mountain Cancer Center, Denver, Colorado

Yale Cancer Center, New Haven, Connecticut

Medical Oncology Hematology Consultants, Newark, Delaware

University of Miami - Sylvester Comprehensive Cancer Center, Miami, Florida

Advent Health, Orlando, Florida

Florida Cancer Specialists South, Port Charlotte, Florida

Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois

Indiana University, Indianapolis, Indiana

Massachusetts General Hospital, Boston, Massachusetts

Dana Farber Cancer Institute, Boston, Massachusetts

Karmanos Cancer Institute, Detroit, Michigan

New York University - Long Island Hospital, Mineola, New York

New York University Perlmutter Cancer Center, New York City, New York

Memorial Sloan Kettering, New York, New York

Duke University, Durham, North Carolina

The Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio

University of Oklahoma, Oklahoma City, Oklahoma

Oregon Health & Science University (OHSU), Portland, Oregon

Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania

WellSpan York Cancer Center, York, Pennsylvania

Medical University of South Carolina, Charleston, South Carolina

Sarah Cannon Research Institute, Nashville, Tennessee

Vanderbilt University Medical Center - Ingram Cancer Center, Nashville, Tennessee

New Experimental Therapeutics - NEXT Oncology, Austin, Texas

UTSW - Moody Outpatient Center - Parkland Health, Dallas, Texas

UT Southwest Simmons Cancer Center, Dallas, Texas

The University of Texas MD Anderson Cancer Center, Houston, Texas

New Experimental Therapeutics of San Antonio - NEXT Oncology, San Antonio, Texas

Virginia Cancer Specialists, Fairfax, Virginia

University of Washington, Fred Hutchinson Cancer Center, Seattle, Washington

Swedish Medical Center, Seattle, Washington

University of Wisconsin Carbone Cancer Center, Madison, Wisconsin

Chris O'Brien Lifehouse Hospital, Camperdown, New South Wales

Mater Cancer Care Centre, South Brisbane, Queensland

Flinders Medical Center, Bedford Park, South Australia

Monash Medical Centre, Clayton, Victoria

Linear Clinical Research, Nedlands, Western Australia

ICANS - Institut de cancérologie Strasbourg Europe, Strasbourg, Bas-Rhin

Institut Bergonie, Bordeaux, Gironde

Institut Claudius Regaud, Toulouse, Haute-Garonne

EDOG Institut de Cancerologie de l'Ouest, Saint-Herblain, Loire-Atlantique

Centre Jean Perrin, Clermont-Ferrand, Puy-de-Dôme

Institut Gustave Roussy, Villejuif, Val-de-Marne

Centre Léon Bérard Centre Régional de Lutte Contre Le Cancer, Lyon, Not set

CHU de Nîmes, Nîmes, Not set

Institute Cancer De Lorraine, Vandœuvre-lès-Nancy, Not set

Nationale Centrum für Tumorerkrankungen (NCT) Heidelberg, Heidelberg, Baden-Württemberg

Universitätsklinikum Augsburg, Augsburg, Bayern

Universitätsklinikum Frankfurt, Frankfurt, Hessen

Universitätsklinikum Essen, Essen, Nordrhein-Westfalen

Asklepios Klinik Altona, Hamburg, Not set

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Lazio

Istituti Fisioterapici Ospitalieri - Istituto Nazionale Tumori Regina Elena, Rome, Lazio

ASST Grande Ospedale Metropolitano Niguarda, Milano, Lombardia

Fondazione IRCCS Istituto Nazionale Dei Tumori, Milano, Lombardia

Istituto Europeo Di Oncologia, Milano, Lombardia

Istituto Clinico Humanitas, Rozzano, Lombardia

Fondazione del Piemonte per l'Oncologia (IRCCS), Candiolo, Torino

IRCCS - lstituto Nazionale Tumori - Fondazione G. Pascale, Napoli, Not set

Asan Medical Center, Seoul, Not set

National Cancer Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Seoul University Hospital, Seoul, Not set

Severance Hospital Yonsei University, Seoul, Not set

National University Hospital, Kent Ridge, Not set

National Cancer Center of Singapore, Singapore, Not set

Instituto de Investigacion Oncologica Vall d'Hebron (VHIO) - EPON, Barcelona, Not set

NEXT Oncology-Hospital Quironsalud Barcelona, Barcelona, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

START MADRID_Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set

START MADRID_Hospital Universitario HM Sanchinarro - CIOCC, Madrid, Not set

START Rioja, Rioja, Not set

Hospital Clinico Universitario de Valencia, Valencia, Not set

Sarah Cannon Research Institute UK, London, Middlesex

Freeman Hospital, Newcastle Upon Tyne, Tyne and Wear

Conditions: Advanced Solid Tumor, Advanced Malignant Neoplasm, Metastatic Cancer, Metastatic Solid Tumor, Lung Cancer, Ovarian Cancer, Endometrial Cancer, Prostate Cancer, Colorectal Cancer, Breast Cancer, Other Cancer, Locally Advanced, Head and Neck Cancer, Gall Bladder Cancer, Small Cell Lung Cancer, Small Cell Lung Cancer ( SCLC ), Small Cell Lung Carcinoma, NSCLC, NSCLC (non-small Cell Lung Cancer), SCLC, Non-Small Cell Lung Carcinoma, Triple Negative Breast Cancer, TNBC, HER2+ Breast Cancer, Non-Small Cell Lung Cancer, ER/PR Positive Breast Cancer, HER2- Breast Cancer, HER2-positive Breast Cancer, HER2-negative Breast Cancer, ER/PR(+), Her2(-) Breast Cancer

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TRAcking Thoracic Cancer Evolution Through Therapy (Rx) EVO

NCT05628376

Recruiting

TRACERx EVO is a programme of work using a prospective observational cohort study of participants with early- and late-stage non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC) and pleural mesothelioma.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

03/27/2025

Locations: University College London Hospitals NHS Foundation Trust, London, Not set

Conditions: Lung Cancer, Non-small Cell, Small Cell Lung Cancer, Pleural Mesothelioma

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