Urothelial Carcinoma Clinical Trials in United Kingdom

A listing of 3 Urothelial Carcinoma clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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There are currently 3 active clinical trials seeking participants for Urothelial Carcinoma research studies. The states with the highest number of trials for Urothelial Carcinoma participants are .

Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2

NCT05911295

Recruiting

This study will enroll participants with urothelial cancer (UC). UC can include cancer of the bladder, kidney, or the tubes that carry pee through the body (ureter, urethra). This study will try to find out if the drugs disitamab vedotin with pembrolizumab works better than platinum-containing chemotherapy to treat patients with UC. This study will also test what side effects happen when participants take these drugs together. A side effect is anything a drug does to the body besides treating th... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: Banner Gateway Medical Center, Gilbert, Arizona +328 locations

Banner Gateway Medical Center, Gilbert, Arizona

Banner MD Anderson Cancer Center, Gilbert, Arizona

UCLA Hematology/Oncology - Alhambra, Alhambra, California

Foothill Cardioology, Arcadia, California

Beverly Hills Multi-Specialties Practice, Beverly Hills, California

Providence Saint Joseph Medical Center, Burbank, California

UCLA Burbank Cardiology, Burbank, California

UCLA Hematology/Oncology - Burbank, Burbank, California

UCLA Calabasas Specialty Care, Calabasas, California

UCLA Encino Specialty Care (Radiology), Encino, California

UCLA Hematology/Oncology - Encino, Encino, California

Helios Clinical Research, Glendale, California

Foothill Cardiology Glendora, Glendora, California

Helios Clinical Research, Long Beach, California

UCLA Downtown Los Angeles Primary & Specialty Care, Los Angeles, California

Administrative Address: UCLA Hematology/Oncology, Los Angeles, California

UCLA Cardiovascular Center, Los Angeles, California

UCLA Hematology & Oncology Clinic, Los Angeles, California

UCLA Hematology / Oncology, Los Angeles, California

UCLA Westwood Specialty Care, Los Angeles, California

UCLA Montecito Primary & Specialty Care, Montecito, California

Pacific Cancer Care, Monterey, California

Newport Diagnostics, Newport Beach, California

Foothill Cardiology Pasadena, Pasadena, California

Southern California Heart Specialists, Pasadena, California

UCLA Porter Ranch Primary & Specialty Care, Porter Ranch, California

UCSF Center at China Basin Imaging, San Francisco, California

Helen Diller Family Comprehensive Cancer Center - Imaging Divisadero, San Francisco, California

Helen Diller Family Comprehensive Cancer Center - Imaging Post, San Francisco, California

UCSF Cancer Center MZ Phlebotomy, San Francisco, California

UCSF Mount Zion Phlebotomy, San Francisco, California

Helen Diller Family Comprehensive Cancer Center - Imaging Parnassus, San Francisco, California

UCSF Parnassus Phlebotomy, San Francisco, California

UCSF Parnassus-5 Lab, San Francisco, California

Cardiovascular Care and Prevention Center at Mission Bay, San Francisco, California

UCSF Investigational Drugs Pharmacy, San Francisco, California

UCSF Mission Bay Gateway-2 Lab, San Francisco, California

UCSF Mission Bay PCMB-5 Lab, San Francisco, California

UCSF Mission Bay Pediatric Clinical Research Center, San Francisco, California

UCSF Mission Bay Radiology and Nuclear Medicine, San Francisco, California

University of California San Francisco, San Francisco, California

University of California, San Francisco | HDFCCC - Hematopoietic malignancies, San Francisco, California

Diagnostic Medical Group of Southern California, , San Gabriel, CA, San Gabriel, California

Southern California Heart Centers, San Gabriel, California

UCLA Hematology/Oncology - San Luis Obispo, San Luis Obispo, California

Sierra Vista Regional Medical Center, San Luis Obispo, California

Helios Clinical Research, Santa Ana, California

UCLA Hematology/Oncology - Santa Barbara, Santa Barbara, California

UCLA Hematology/Oncology - Santa Monica, Santa Monica, California

UCLA Simi Valley Alamo Specialty Care, Simi Valley, California

Twin Cities Community Hospital, Templeton, California

UCLA Thousand Oaks Primary & Specialty Care, Thousand Oaks, California

UCLA Hematology/Oncology - Torrance, Torrance, California

UCLA Torrance Lomita Specialty Care, Torrance, California

UCLA Santa Clarita Primary & Specialty Care, Valencia, California

UCLA Ventura Cardiology, Ventura, California

UCLA Hematology/Oncology - Westlake, Westlake Village, California

Helios Clinical Research, Whittier, California

Greater Baltimore Medical Center, Baltimore, Maryland

M Health Fairview Ridges Cancer Clinic, Burnsville, Minnesota

M Health Fairview Cancer Clinic-Edina, Edina, Minnesota

Minnesota Oncology Hematology Pa, Edina, Minnesota

Minnesota Oncology Hematology, PA, Fridley, Minnesota

M Health Fairview Maple Grove Cancer Center, Maple Grove, Minnesota

Allina Health Cancer Institute-United(VPCI), Minneapolis, Minnesota

Hennepin Country Medical Center, Minneapolis, Minnesota

M Health Fairview University of Minnesota Investigational Drug Services, Minneapolis, Minnesota

Metro Minnesota Community Oncology Research Consortium(MMCORC), Saint Louis Park, Minnesota

Regions Hospital, Saint Paul, Minnesota

M Health Fairview Lakes Medical Center, Wyoming, Minnesota

Nebraska Medicine- Bellevue Medical Center, Bellevue, Nebraska

Nebraska Medicine -Nebraska Medical Center, Omaha, Nebraska

Nebraska Medicine-Cancer Center at Village Pointe Health Center, Omaha, Nebraska

The University of Nebraska Medical Center, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

Optum Care Cancer Care at Seven Hills, Las Vegas, Nevada

OptumCare Cancer center, Las Vegas, Nevada

OptumCare Cancer Center Care at Fort Apache, Las Vegas, Nevada

Icahn School of Medicine at Mount Sinai, New York, New York

Ship study drug to: Mount Sinai Hospital- Pharmacy Dept, New York, New York

ECU Health Medical Center, Greenville, North Carolina

AHN Saint Vincent Hospital, Erie, Pennsylvania

AHN Jefferson Hospital, Jefferson Hills, Pennsylvania

AHN Forbes Hospital, Monroeville, Pennsylvania

Allegheny Valley Hospital, Natrona Heights, Pennsylvania

AHN Cancer Institute - Allegheny General Hospital, Pittsburgh, Pennsylvania

AHN Cancer Institute Pharmacy, Pittsburgh, Pennsylvania

AHN West Penn Hospital, Pittsburgh, Pennsylvania

UT Southwestern Medical Center - Redbird, Dallas, Texas

University of Texas Southwestern Medical Center - Simmons Cancer Center, Dallas, Texas

University of Texas Southwestern Medical Center-Simmons Cancer Center Pharmacy, Dallas, Texas

University of Texas Southwestern Medical Center, Dallas, Texas

UT Southwestern - Simmons Cancer Center - Fort Worth, Fort Worth, Texas

UT Southwestern - Simmons Cancer Center - Richardson/Plano, Richardson, Texas

Inova Schar Cancer Institue Infusion Pharmacy, Fairfax, Virginia

Inova Schar Cancer Institute, Fairfax, Virginia

Harborview Medical Center, Seattle, Washington

Fred Hutchinson Cancer Center., Seattle, Washington

University of Washington Medical Center, Seattle, Washington

Clinica Viedma, Viedma, RIO Negro

Fundación Dr. Ruben Kowalyszyn, Viedma, RÍO Negro

Comisión Provincial de Evaluación de Proyectos de Investigación en Salud Humana (CEEPISH), Viedma, RÍO Negro

Centro de Oncologia e Investigacion de Buenos Aires (COIBA), Berazategui, Not set

Instituto Médico Especializado Alexander Fleming, Buenos Aires, Not set

Centro Medico Austral, Buenos Aire, Not set

Centro Oncologico Korben, Buenos Aire, Not set

Fundacion Cenit, Caba, Not set

Investigaciones Clinicas Moleculares (ICM), Caba, Not set

CEMAIC - Centro Medico Privado, Cordoba, Not set

Hospital Municipal de Morón. O. B. Lavignolle, Morón, Not set

Centro de Investigacion Pergamino SA, Pergamino, Not set

Comité Provincial de Bioética-Rosario, Rosario, Not set

Sanatorio Parque, Rosario, Not set

Consultorio Dr. Miguel Angel Escudero, Salta, Not set

Oncologia Salta, Salta, Not set

Centro para la Atencion Integral del paciente Oncologico, Tucuman, Not set

Concord Repatriation General Hospital, Concord, New South Wales

Saint Vincents Hospital Sydney - Human Research Ethics Committee, Darlinghurst, New South Wales

St Vincent's Clinic, Darlinghurst, New South Wales

Macquarie University Hospital, Macquarie University, New South Wales

Macquarie University, North Ryde, New South Wales

Prince of Wales Hospital, Randwick, New South Wales

North Shore Private Hospital, St Leonards, New South Wales

Mater Misericordiae - Mater Hospital Brisbane, Brisbane, Queensland

Icon Cancer Centre Chermside, Herston, Queensland

Mater Research, South Bribane, Queensland

Peninsula & South Eastern Hematology and Oncology Group (PASO), Frankston, Victoria

Austin Health, Melbourne, Victoria

South Eastern Sydney Local Health District, Caringbah, Not set

Lyell McEwin Hospital, Elizabeth Vale, Not set

Peninsula And South East Oncology, Frankston, Not set

Cabrini., Malvern, Not set

Mid North Coast Local Health District, NSW, Not set

Port Macquarie Base Hospital, Port Macquarie, Not set

Mater Cancer Care Centre, South Brisbane, Not set

Royal North Shore Hospital, St Leonards, Not set

Algemeen Ziekenhuis Maria Middelares, Gent, Not set

AZ St. Lucas, Ghent, Not set

University Hospital Ghent, Ghent, Not set

CHU de Liege Service Oncologie Medicale, Liege, Not set

CHU UCL Namur-Site de Saint Elisabeth, Namur, Not set

GZA Hospital Sint-Augustinus, Wilrijk, Not set

Centro de Oncologia da Bahia, Salvador, BA

Suporte Nutricional e Quimioterapia - PRONUTRIR, Fortaleza, Ceará

Associacao Mario Penna - Hospital Luxemburgo - NEPI Nucleo de Ensino Pesquisa e Inovacao, Belo Horizonte, MG

Hospital Sao Vicente de Paulo, Passo Fundo, RIO Grande DO SUL

Hospital Mae de Deus, Porto Alegre, RIO Grande DO SUL

Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Porto Alegre, RS

Hospital Nossa Senhora da Conceicao / Grupo Hospitalar Conceicao, Porto Alegre, RS

Fundacao Doutor Amaral Carvalho, Jaú, SÃO Paulo

Hospital de Cancer de Barretos - Fundacao Pio XII, Barretos, Not set

Erasto Gaertner Hospital, CuriBba, Not set

Hospital Alemao Oswaldo Cruz, Sao Paulo, Not set

Arthur J.E. Child Comprehensive Cancer Centre, Calgary, Alberta

University of Alberta / Cross Cancer Institute, Edmonton, Alberta

Lakeridge Health - The R.S. McLaughlin Durham Regional Cancer Centre (MDRCC), Oshawa, Ontario

Princess Margaret Cancer Centre - University Health Network, Toronto, Ontario

Centro de Estudios Clínicos SAGA, Santiago, Not set

Centro de Investigaciones Clinicas Vina del Mar, Vina del mar, Not set

Fakultni nemocnice Hradec Kralove, Hradec Kralove, Hradec Králové

Fakultni Nemocnice Olomouc (Fnol) - Onkologicka Klinika, Olomouc, Not set

University Hospital of Besancon, Besancon, Not set

Institut Bergonié Centre de Lutte Contre le Cancer (CLCC), Bordeaux Cedex, Not set

Centre de Lutte contre le Cancer - François Baclesse, Caen Cedex 5, Not set

Institut Paoli Calmettes, Marseille, Not set

Institut régional du Cancer de Montpellier - ICM Val d'Aurelle, MONTPELLIER Cedex 5, Not set

Pharmacy ICM Val d'Aurelle - Bat A - Rez-de-Jardin, MONTPELLIER Cedex 5, Not set

Centre de Lutte contre le Cancer (CLCC) - Centre Antoine Lacassagne, Nice Cedex 2, Not set

Hopital Europeen Georges Pompidou, Paris, Not set

Hospices Civils de Lyon, Pierre Benite, Not set

Unite de Coordination de la Biologie des Essais Cliniques, Strasbourg, Not set

Institut de Cancerologie Strasbourg Europe, Strasbourg, Not set

Institut Gustave Roussy, Villejuif Cedex, Not set

Athens Medical Center, Maroussi, Attikí

Bioclinic Thessalonikis Private Clinic Single Member S.A., Thessaloniki, Kentrikí Makedonía

Metropolitan General Hospital, Cholargos, Not set

Semmelweis Egyetem Urologiai Klinika, Budapest, Not set

Bacs-Kiskun Varmegyei Oktatokorhaz, Kecskemét, Not set

Rajiv Gandhi Cancer Institute And Research Centre, New Delhi, Delhi

Nirmal Hospital Pvt Ltd, Surat, Gujarat

Cancer Trials Cork, Cork, Not set

Tallaght University Hospital, Tallaght, Not set

Cork University Hospital, Wilton, Not set

Shaare Zedek Medical Center, Jerusalem, Other

Hadassah Medical Center, Jerusalem, Other

Sheba Medical Center., Ramat Gan, Other

Emek Medical Center, Afula, Not set

Soroka Medical Center, Be'er Sheva, Not set

Rambam Health Care Campus, Hafia, Not set

Meir Medical Center, Kefar Sava, Not set

Rabin Medical Center, Petach Tikva, Not set

Kaplan Medical Center, Rehovot, Not set

Tel Aviv Sourasky Medical Center, Tel Aviv, Not set

IRCCS Istituto Tumori Giovanni Paolo II, Bari, Apulia

Azienda Ospedaliera Cardinale Giovanni Panico, Tricase, Apulia

Oncologia Medica, Ospedale Civile S. Maria delle Croci, Ravenna, Emilia-romagna

Ospedale Policlinico San Martino, Genova, Liguria

Ospedale San Raffaele, Milano, Lombardy

Istituto Clinico Humanitas-Humanitas Cancer Center, Rozzano (Milano), Lombardy

IRCCS Istituto Clinico Humanitas, Rozzano, Milano

IRCCS - Ospedale San Raffaele, Milano, Milan

Azienda Sanitaria Locale Napoli 2 Nord, Giugliano in Campania, Naples

Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, Bari, Other

P.O. "S. Maria Delle Grazie" - Pozzuoli - ASL Napoli Nord 2, Pozzuoli (NA), Other

ASL-AT, Ospedale Cardinal Massaia di Asti, Asti, Piemonte

SOSD Farmacia Ospedaliera, Aviano, Pordenone

Centro di Riferimento Oncologico Di Aviano, Aviano, Pordenone

AUSL Romagna - Presidio Ospedale "Umberto I" di Lugo, Lugo, Ravenna

AUSL della Romagna - Ospedale degli infermi, Faenza, RA

Azienda Ospedaliero Universitaria Careggi, Firenze, Tuscany

Azienda Ospedaliera S. Maria di Terni, Terni, Umbria

ASL Asti - Ospedale Cardinal Massaia - S.C. Farmacia Ospedaliera, Asti, Not set

ASST Cremona Farmacia Ospedaliera, Cremona, Not set

U.O. Farmacia Ospedaliera a Politiche del Farmaco Az. Osp. Universitaria Careggi, Firenze, Not set

Ospedale Policlinico San Martino Farmacia, Genova, Not set

Istituto Nazionale Tumori IRCCS Fondazione G.Pascale Napoli Pascale, Napoli, Not set

SC Farmacia Ospedaliera C/O Istituto Nazionale Tumori IRCCS Fondazione G.Pascale Napoli Pascale, Napoli, Not set

Istituto Oncologico Veneto - IRCCS, Padova, Not set

Azienda Ospedaliera Universitaria Pisana Ospedale Santa Chiara, Pisa, Not set

Azienda Ospedaliera Universitaria Pisana, U.O. Farmacia Ospedaliera, Pisa, Not set

Policlinico Universitario Agostino Gemelli, Roma, Not set

Centro Ricerche Cliniche Di Verona Srl, Verona, Not set

Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Not set

Hirosaki University Hospital, Hirosaki, Aomori

Ehime University Hospital, Toon, Ehime

National Hospital Organization Kyushu Cancer Center, Fukuoka-shi, Fukuoka

Gunma Prefectural Cancer Center, Ota-Shi, Gunma

Kobe University Hospital, Kobe-shi, Hyogo

University of Tsukuba Hospital, Tsukuba, Ibaraki

Kagawa University Hospital, Kita-gun, Kagawa

Yokohama City University Medical Center, Yokohama, Kanagawa

Kanagawa Cancer Center, Yokohama, Kanagawa

University of Miyazaki Hospital, Miyazaki City, Miyazaki

Nara Medical University Hospital, Kashihara, Nara

Kindai University Hospital, Osakasayama-Shi, Osaka

Osaka University Hopsital, Suita-city, Osaka

Tokushima University Hospital, Tokushima-Shi, Tokushima

Keio University Hospital, Shinjuku-ku, Tokyo

Wakayama Medical University Hospital, Wakayama-shi, Wakayama

Yamaguchi University Hospital, Ube, Yamaguchi

Chiba Cancer Center, Chiba, Not set

National Hospital Organization Kumamoto Medical Center, Kumamoto, Not set

Osaka Prefectural Hospital Organization - Osaka International Cancer Institute, Osaka, Not set

Yamagata University Hospital, Yamagata, Not set

National Cancer Center, Goyang-si, Gyeonggi-do

CHA Bundang Medical Center, CHA University, Seongnam-si, Gyeonggi-do

The Catholic University of Korea, St. Vincent's Hospital, Suwon-si, Gyeonggi-do

Jeonbuk National University Hospital, Jeonju-si, Jeollabuk-do

Chonnam National University Hwasun Hospital, Hwasun-gun, Jeollanam-do

Wonkwang University Hospital, Iksan-si, Jeonlabuk-do

Inje University Haeundae Paik Hospital, Busan, Not set

Kosin University Gospel Hospital, Busan, Not set

Gachon University Gil Medical Center, Incheon, Not set

Seoul National University Bundang Hospital, Seongnam-si, Not set

Korea University Anam Hospital, Seoul, Not set

Kangbuk Samsung Hospital, Seoul, Not set

Severance Hospital Yonsei University Health System, Seoul, Not set

Asan Medical Center - Oncology, Seoul, Not set

Amphia Ziekenhuis, Breda, Noord-brabant

Haga Ziekenhuis, Den Haag, Zuid-holland

Antoni van Leeuwenhoek Apotheek,I-2, Amsterdam, Not set

Netherlands Cancer Institute/Antoni van Leeuwenhoek, Amsterdam, Not set

Rijnstate Hospital, Arnhem, Not set

Maastricht Universitair Medisch Centrum+, Maastricht, Not set

Radboud University Medical Center, Nijmegen, Not set

Akershus universitetssykehus HF, Lørenskog, Akershus

Avdeling for blod og kreft sykdommer. Stavanger universitetssykehus, Stavanger, Not set

Hospital Militar Central Coronel Luis Arias Schreiber, Lima, Not set

Hospital Maria Auxiliadora, Lima, Not set

Hospital de Braga, Sao Victor, Braga

Hospital de Braga, Braga, Not set

Centro Clinico Champalimaud, Lisboa, Not set

Hospital de Santa Maria - Centro Hospitalar Universitario Lisboa Norte, Lisboa, Not set

Champalimaud Clinical Center, Lisbon, Not set

Centro Hospitalar Universitário de São João, Porto, Not set

National University Hospital, Singapore, Not set

National University Cancer Institute, Singapore, Not set

National Cancer Centre Singapore, Singapore, Not set

Raffles Hospital, Singapore, Not set

Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, A Coruna

Farmacia Oncologica - Unidad de Ensayos Clinicos, Santiago de Compostela, A Coruna

Hospital Universitario Badajoz, Badajoz, A Coruña [LA Coruña]

Institut Catala d' Oncologia de Badalona - Hospital Universitari Germans Trias i Pujos, Badalona, Barcelona

Institut Catala d'Oncologia Badalona (ICO Badalona) - Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona

Institut Catala d'Oncologia - Hospital Duran i Reynals (ICO L'Hospitalet), L'Hospitalet de Llobregat, Barcelona

Hospital de Cruzes, Barakaldo, Bizkaia

Hospital Universitario Marques de Valdecilla, Santander, Cantabria

Hospital Universitario Puerta de Hierro - Majadahonda, Majadahonda, Madrid

Infanta Cristina Hospital, Badajoz, Not set

Hospital Del Mar, Barcelona, Not set

Hospital Universitari Vall D Hebron, Barcelona, Not set

Hospital Universitari Vall d'Hebron, Barcelona, Not set

Hospital Clinic de Barcelona, Barcelona, Not set

Hospital de la Santa Creu i Sant Pau- Pharmacy, Barcelona, Not set

Hospital de La Santa Creu i Sant Pau, Barcelona, Not set

Unitat d'Assajos Clinics Servei de Farmacia, L'Hospitaler De Llobregat, Not set

Complejo Hospitalario Universitario Insular Materno-Infantil, Las Palmas de Gran Canaria, Not set

Hospital General Universitario Gregorio Maranon, Madrid, Not set

MD Anderson Cancer Center Madrid, Madrid, Not set

Hospital Universitario Ramon y Cajal, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario La Paz: Servicio de Farmacia, Madrid, Not set

Hospital Universitario La Paz, Madrid, Not set

HM Centro Integral Oncologico Clara Campal, Madrid, Not set

Hospital Universitario HM Sanchinarro, Madrid, Not set

Complejo Hospitalario Universitario de Ourense (CHOU), Ourense, Not set

Hospital Universitario Virgen Del Rocio, Sevilla, Not set

Consorcio Hospital General Universitario de Valencia (CHGUV), Valencia, Not set

Consorcio Hospital General Universitario de Valencia, Valencia, Not set

Hospital Universitario Miguel Servet, Zaragoza, Not set

Ryhov Hospital, Jonkoping, Not set

Karolinska University Hospital, Stockholm, Not set

Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City, Not set

Chang Gung Memorial Hospital Kaohsiung Branch, Kaohsiung City, Not set

Kaohsiung Medical University Hospital, Kaohsiung, Not set

China Medical University Hospital - Pharmacy, Taichung, Not set

China Medical University Hospital, Taichung, Not set

Taichung Veterans General Hospital Clinical Trials Pharmacy, Taichung, Not set

Taichung Veterans General Hospital, Taichung, Not set

Chi Mei Hospital liouying, Tainan City, Not set

Clinical Trial Pharmacy, Department of Pharmacy, National Cheng Kung University Hospital, Tainan, Not set

National Cheng-Kung University Hospital, Tainan, Not set

National Taiwan University Hospital, Investigational Drug Service, Taipei, Not set

National Taiwan University Hospital, Taipei, Not set

NHS Greater Glasgow and Clyde (NHSGGC) - The Beatson West of Scotland Cancer Centre, Glasgow, Other

Barts Health NHS Trust Saint Bartholomews Hospital, London, Not set

Guy's and St Thomas' NHS Foundation Trust, London, Not set

Guy's and St Thomas' NHS Foundation, London, Not set

Conditions: Urothelial Carcinoma

Learn More ›

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

NCT04879329

Recruiting

This study is being done to see if a drug called disitamab vedotin, alone or with pembrolizumab, works to treat HER2 expressing urothelial cancer. It will also test how safe the drug is for participants. Participants will have cancer that has spread in the body near where it started (locally advanced) and cannot be removed (unresectable) or has spread through the body (metastatic). It will also study what side effects happen when participants get the drug. A side effect is anything a drug does... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/06/2025

Locations: Banner Gateway Medical Center, Gilbert, Arizona +179 locations

Banner Gateway Medical Center, Gilbert, Arizona

Banner MD Anderson Cancer Center, Gilbert, Arizona

Kaiser Permanente Anaheim Kraemer Medical Offices, Anaheim, California

Kaiser Permanente Baldwin Park Medical Center, Baldwin Park, California

Kaiser Permanente Bellflower Medical Offices, Bellflower, California

City of Hope (City of Hope National Medical Center, City of Hope Medical Center), Duarte, California

Kaiser Permanente Fontana Medical Center, Fontana, California

Kaiser Permanente South Bay Medical center, Harbor City, California

Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine, California

Kaiser Permanente Alton/Sand Canyon Medical Offices, Irvine, California

Kaiser Permanente Los Angeles Medical Offices, Los Angeles, California

Kaiser Permanente West Los Angeles Medical Center, Los Angeles, California

Valkyrie Clinical Trials, Los Angeles, California

Ronald Reagan UCLA Medical Center, Drug Information Center, Los Angeles, California

UCLA Hematology Oncology, Los Angeles, California

Kaiser Permanente Ontario Medical Center, Ontario, California

UC Irvine Health, Orange, California

Kaiser Permanente Panorama City Medical Center, Medical Offices 3, Panorama City, California

Kaiser Permanente Riverside Medical Center, Riverside, California

Southern California Permanente Medical Group (SCPMG), Riverside, California

Kaiser Permanente San Diego Mission Road (Regulatory and Lab Supplies), San Diego, California

Kaiser Permanente Zion Medical Center, San Diego, California

UCSF Cancer Center MZ Phlebotomy, San Francisco, California

UCSF Mount Zion Phlebotomy, San Francisco, California

UCSF Parnassus Phlebotomy, San Francisco, California

UCSF Investigational Drugs Pharmacy, San Francisco, California

University of California, San Francisco | HDFCCC - Hematopoietic Malignancies, San Francisco, California

University of California, San Francisco, San Francisco, California

Kaiser Permanente San Marcos Medical Offices, San Marcos, California

UCLA Hematology/Oncology - Santa Monica, Santa Monica, California

Kaiser Permanente Woodland Hills Medical Center, Woodland Hills, California

Medstar Washington Hospital Center, Washington, District of Columbia

Florida Cancer Specialists, Bonita Springs, Florida

Florida Cancer Specialists, Bradenton, Florida

Florida Cancer Specialists, Cape Coral, Florida

Florida Cancer Specialists, Daytona Beach, Florida

Florida Cancer Specialists, Fleming Island, Florida

Florida Cancer Specialists, Fort Myers, Florida

Florida Cancer Specialists, Naples, Florida

Florida Cancer Specialists, Port Charlotte, Florida

Florida Cancer Specialists, Sarasota, Florida

Florida Cancer Specialists, Stuart, Florida

Florida Cancer Specialists, Tallahassee, Florida

Moffitt Cancer Center McKinley Hospital, Tampa, Florida

Florida Cancer Specialists, Venice, Florida

Florida Cancer Specialists, Vero Beach, Florida

Florida Cancer Specialists, Wellington, Florida

Florida Cancer Specialists, West Palm Beach, Florida

Northwest Georgia Oncology Centers, a Service of Tanner Medical Center Villa Rica, Carrollton, Georgia

West Georgia Infusion Center, a Service of Tanner Medical Center Villa Rica, Carrollton, Georgia

Northwest Georgia Oncology Centers, a Service of WellStar Cobb Hospital, Cartersville, Georgia

Northwest Georgia Oncology Centers, a Service of WellStar Cobb Hospital, Douglasville, Georgia

Northwest Georgia Oncology Centers, a Service of WellStar Cobb Hospital, Hiram, Georgia

WellStar Paulding Hospital, Hiram, Georgia

Northwest Georgia Oncology Centers, a Service of WellStar Cobb Hospital, Marietta, Georgia

Northwest Georgia Oncology Centers, Marietta, Georgia

UChicago Medicine - River East, Chicago, Illinois

University of Chicago Medical Center, Chicago, Illinois

Accellacare - Deerfield, Deerfield, Illinois

UChicago Medicine at Ingalls - Flossmoor, Flossmoor, Illinois

UChicago Medicine Ingalls Memorial, Harvey, Illinois

University of Chicago Comprehensive Cancer Center at Silver Cross Hospital, New Lenox, Illinois

The University of Chicago Medicine Center for Advanced Care Orland Park, Orland Park, Illinois

UChicago Medicine at Ingalls - Tinley Park, Tinley Park, Illinois

UMass Memorial Medical Center, Worcester, Massachusetts

University of Massachusetts Chan Medical School, Worcester, Massachusetts

Karmanos Cancer Institute, Detroit, Michigan

Henry Ford Hospital, Detroit, Michigan

Karmanos Cancer Institute Weisberg Cancer Treatment Center, Farmington Hills, Michigan

Cancer & Hematology Centers of Western Michigan, PC, Grand Rapids, Michigan

Cancer & Hematology Centers of Western Michigan, PC- Kit Storage, Grand Rapids, Michigan

Cancer & Hematology Centers of Western Michigan, PC, Holland, Michigan

Karmanos Cancer Institute at McLaren Greater Lansing, Lansing, Michigan

Cancer & Hematology Centers of Western Michigan, PC, Norton Shores, Michigan

MSK Basking Ridge, Basking Ridge, New Jersey

MSK Monmouth, Middletown, New Jersey

MSK Bergen, Montvale, New Jersey

MSK Wesrchester, Harrison, New York

Northwell Health, Lake Success, New York

Memorial Sloan Kattering Cancer Centre- Investigational Drug Service Pharmacy, Long Island City, New York

Ship study drug to: Mount Sinai Hospital- Pharmacy Dept, New York, New York

Evelyn H. Lauder Breast and Imaging Centre (BAIC), New York, New York

Memorial Sloan Kettering Cancer Center - Main Campus, New York, New York

Sidney Kimmel Centre for Prostate and Urological Cancer, New York, New York

SUNY Upstate Medical University, Syracuse, New York

MSK nassau, Uniondale, New York

UNC Hospitals, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

UNC Lineberger Comprehensive Cancer Center / University of North Carolina, Chapel Hill, North Carolina

Carolinas Medical Center (biopsy only), Charlotte, North Carolina

Carolinas Medical Center Investigational Drug Services, Charlotte, North Carolina

Levine Cancer Institute, Charlotte, North Carolina

Atrium Health Mercy (biopsy only), Charlotte, North Carolina

Atrium Health Pineville (biopsy only), Charlotte, North Carolina

Atrium Health University City (biopsy only), Charlotte, North Carolina

Levine Cancer Institute University, Charlotte, North Carolina

Levine Cancer Institute - Ballantyne, Charlotte, North Carolina

Atrium Health Cabarrus (biopsy only), Concord, North Carolina

Levine Cancer Institute Concord, Concord, North Carolina

Atrium Health Union (biopsy only), Monroe, North Carolina

University Hospitals Cleveland Medical Center, Cleveland, Ohio

James Cancer Hospital & Solove Research Institute, Columbus, Ohio

Ohio State University Hospital, Columbus, Ohio

Ohio State University, Columbus, Ohio

OSU Wexner Medical Center & James Cancer Hospital, Columbus, Ohio

OU Health Stephenson Cancer Center, Oklahoma City, Oklahoma

OU Medical Center, Oklahoma City, Oklahoma

University of Tennessee Medical Center, Knoxville, Tennessee

Baylor Scott and White Research Institute, Dallas, Texas

The University of Texas MD Anderson Cancer Center, Houston, Texas

Baylor Scott & White Medical Center - Temple, Temple, Texas

Huntsman Cancer Institute at The University of Utah, Salt Lake City, Utah

Inova Schar Cancer Institute, Fairfax, Virginia

Harborview Medical Center, Seattle, Washington

Fred Hutchinson Cancer Center, Seattle, Washington

University of Washington Medical Center, Seattle, Washington

Froedtert Hospital/Medical College of Wisconsin, Milwaukee, Wisconsin

Clinica Viedma, Viedma, RÍO Negro

Fundacion Cenit, Caba, Not set

Centro Medico Austral, Caba, Not set

Centro Oncologico Korben, Caba, Not set

Hospital Aleman, Ciudad autonoma de Buenos Aires, Not set

Instituto Medico Especializado Alexander Fleming, Ciudad Autonoma de Buenos Aires, Not set

Hospital Sirio Libanes - Buenos Aires, Ciudad Autonoma de Buenos Aires, Not set

Instituto Oncologico de Cordoba, Cordoba, Not set

GenesisCare - North Shore, St Leonards, New South Wales

Macquarie University, Sydney, New South Wales

Mater Cancer Care Centre, Mater Misericordiae Limited, South Brisbane, Queensland

Peninsula & South Eastern Haematology and Oncology Group, Frankston, Victoria

Lyell McEwin Hospital, Elizabeth Vale, Not set

Princess Alexandra Hospital, Woolloongabba, Not set

AZ Maria Middelares, Gent, Not set

CHU UCL Namur-Site de Saint Elisabeth, Namur, Not set

Arthur J.E. Child Comprehensive Cancer Centre, Calgary, Alberta

BC Cancer - Vancouver Fairmont Medical Building, Vancouver, British Columbia

BC Cancer - Vancouver, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

Jewish General Hospital, Montreal, Quebec

Centre Hospitalier Universitaire de Sherbrooke, Fleurimont, Not set

Oncovida SA, Santiago, Providencia

Pontificia Universidad Catolica de Chile, Santiago, Providencia

IC La Serena Research SpA, La Serena, Not set

Rambam Health Care Campus, Haifa, Not set

Rabin medical Center, Petach Tikva, Not set

Sheba Medical Center, Ramat Gan, Not set

The Chaim Sheba Medical Center, Ramat-Gan, Not set

Tel Aviv Sourasky Medical Center, Tel Aviv, Not set

Ospedale San Raffaele, Milano, Lombardy

Centro di Riferimento Oncologico Di Aviano, Aviano, Pordenone

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Rome

Azienda Ospedaliero Universitaria Pisana, Pisa, Toscana

IRCCS Ospedale San Raffaele, U.O. Farmacia Studi Clinici, Milan, Not set

IOV-Istituto Oncologico Veneto IRCCS-U.O. Oncologia Medica 1-SC Farmacia, Padova, Not set

Azienda Ospedaliero Universitaria Pisana, Pisa, Not set

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Not set

Azienda Ospedaliera S. Maria di Terni, Terni, Not set

S.C. Farmacia Interna, Terni, Not set

National Cancer Center Hospital East, Kashiwa-shi, Chiba

Sapporo Medical University Hospital, Sapporo-shi, Hokkaido

Osaka University Hospital, Suita-shi, Osaka

Tokushima University Hospital, Tokushima-Shi, Tokushima

The Cancer Institute Hospital of JFCR, Koto-ku, Tokyo

Osaka Prefectural Hospital Organization - Osaka International Cancer Institute, Osaka, Not set

Hospital Universitario Virgen del Rocío, Sevilla, Andaluca

Hospital Universitari Parc Tauli Sabadell, Sabadell, Barcelona

Hospital Universitari Vall d'Hebrón, Barcelona, Not set

MD Anderson Cancer Center - Madrid, Madrid, Not set

MD Anderson Cancer Center Madrid, Madrid, Not set

Hospital Universitario Virgen del Rocío, Sevilla, Not set

Beatson West of Scotland Cancer Centre, Glasgow, Scotland

Cambridge University Hospitals NHS Foundation Trust, Cambridge, Not set

Barts Health NHS Trust, St Bartholomew's Hospital, London, Not set

Guy's Hospital, London, Not set

Charing Cross Hospital, London, Not set

The Christie NHS Foundation Trust - Christie Hospital, Manchester, Not set

The Christie NHS Foundation Trust, Manchester, Not set

The Clatterbridge Cancer Centre NHS Foundation Trust, The Clatterbridge Cancer Centre - Wirral, Merseyside, Not set

Conditions: Urothelial Carcinoma

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A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours

NCT04969835

Recruiting

This is a first-in-human (FIH), Phase 1 open-label, multicentre dose escalation study investigating AVA6000 monotherapy administered intravenously in patients with locally advanced (unresectable) or metastatic solid tumours that are likely to be FAP positive. The study consists of an initial Phase 1a dose escalation portion and a subsequent Phase 1b dose expansion portion upon completion of the dose escalation portion.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/10/2025

Locations: Memorial Sloan Kettering Cancer Center, New York, New York +8 locations

Conditions: Breast Cancer, Soft Tissue Sarcoma, Salivary Gland Tumor, Urothelial Carcinoma, Ovarian Carcinoma

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