Surgery With or Without Preoperative Chemotherapy in Treating Patients With Resectable Non-small Cell Lung Cancer
NCT00003159
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if surgery is more effective with or without preoperative chemotherapy in treating non-small cell lung cancer. PURPOSE: This randomized phase III trial is studying surgery and preoperative chemotherapy to see how well they work compared to surgery alone in treating patients with resectable non-small cell lung cancer.
Gender:
ALL
Ages:
All
Trial Updated:
12/03/2013
Locations: Medical Research Council Clinical Trials Unit, London, England +1 locations
Conditions: Lung Cancer
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Surgery Plus Radiation Therapy With or Without Chemotherapy in Treating Children With Primitive Neuroectodermal Tumors of the CNS
NCT00003859
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether undergoing surgery plus radiation therapy is more effective with or without chemotherapy for primitive neuroectodermal tumors of the CNS. PURPOSE: Randomized phase III trial to compare the effectiveness of surgery plus radiation therapy with or without chemotherapy in treating patients... Read More
Gender:
ALL
Ages:
Between 3 years and 16 years
Trial Updated:
12/03/2013
Locations: St. James's Hospital, Leeds, England
Conditions: Brain and Central Nervous System Tumors
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Combination Chemotherapy Before Surgery in Treating Children With Localized Neuroblastoma
NCT00025428
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy drugs before surgery may shrink the tumor so that it can be removed during surgery. PURPOSE: Phase III trial to determine the effectiveness of combination chemotherapy given before surgery in treating children who have localized neuroblastoma.
Gender:
ALL
Ages:
Between 1 year and 18 years
Trial Updated:
12/03/2013
Locations: St. Anna Children's Hospital, Vienna, Not set +11 locations
Conditions: Neuroblastoma
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Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors
NCT00025441
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating children with metastatic rhabdomyosarcoma or other malignant mesenchymal tumors.
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
12/03/2013
Locations: Centre Leon Berard, Lyon, Not set +21 locations
Conditions: Ovarian Cancer, Sarcoma, Small Intestine Cancer
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A Study Of AG-013736 (Axitinib) Or Bevacizumab (Avastin) In Combination With Paclitaxel And Carboplatin In Patients With Advanced Lung Cancer.
NCT00600821
Completed
To determine if the addition of AG-013736 to chemotherapy is beneficial in patients with advanced lung cancer who have not been previously treated.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/16/2013
Locations: Pfizer Investigational Site, Baton Rouge, Louisiana +43 locations
Conditions: Non-Small-Cell Lung Carcinoma, Adenocarcinoma
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Sequential Chemotherapy in Treating Patients With Residual Disease Following Surgery for Stage IIB, Stage III, or Stage IV Ovarian Cancer
NCT00003733
Unknown
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy drugs in different ways may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of sequential chemotherapy in treating patients with residual disease following surgery for stage IIB, stage III, or stage IV ovarian cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
09/19/2013
Locations: Charing Cross Hospital, London, England +1 locations
Conditions: Ovarian Cancer
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Carboplatin and Temozolomide in Treating Patients With Unresectable or Metastatic Melanoma
NCT00003747
Unknown
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combining carboplatin and temozolomide in treating patients who have unresectable or metastatic melanoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/19/2013
Locations: Mount Vernon Hospital, Northwood, England
Conditions: Melanoma (Skin)
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Paclitaxel and Carboplatin Chemotherapy Compared With Standard Chemotherapy in Treating Patients With Stage III or Stage IV Non-small Cell Lung Cancer That Cannot Be Removed During Surgery
NCT00004887
Unknown
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether paclitaxel and carboplatin is more effective than standard chemotherapy for advanced non-small cell lung cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of paclitaxel and carboplatin chemotherapy with that of standard chemotherapy in treating patients who have stage III or stage IV non-small cell lung cancer that cannot be r... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/19/2013
Locations: Christie Hospital N.H.S. Trust, Manchester, England
Conditions: Lung Cancer
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Hospitalization Rates of Patients With Non-Small Cell Lung Cancer Treated With Gemcitabine and Either Cisplatin or Carboplatin
NCT00055965
Unknown
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known if one regimen will require patients to spend more time in the hospital than the other regimen for treatment of chemotherapy-related side effects. PURPOSE: Randomized phase III trial to compare the hospitalization rates of patients who are receiving gemcitabine combined with cisplatin with that of pati... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/19/2013
Locations: Christie Hospital NHS Trust, Manchester, England
Conditions: Lung Cancer
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Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors
NCT00281905
Unknown
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving radiation therapy after chemotherapy may kill any remaining tumor cells. PURPOSE: This phase II trial is studying how well giving combination chemotherapy together with or without radiation... Read More
Gender:
ALL
Ages:
3 years and below
Trial Updated:
09/19/2013
Locations: Our Lady's Hospital for Sick Children, Dublin, Not set +20 locations
Conditions: Brain and Central Nervous System Tumors, Neuroblastoma
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Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy
NCT00683319
Active Not Recruiting
RATIONALE: Gathering information about how young patients with ependymoma respond to standard combination chemotherapy and learning about the long-term effects of this treatment may help doctors plan better treatment. PURPOSE: This phase III trial is observing young patients with ependymoma undergoing standard combination chemotherapy.
Gender:
ALL
Ages:
2 years and below
Trial Updated:
09/19/2013
Locations: Birmingham Children's Hospital, Birmingham, England +9 locations
Conditions: Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Long-term Effects Secondary to Cancer Therapy in Children, Ototoxicity
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High-Dose Chemotherapy Compared With Standard Chemotherapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer That Has Been Removed During Surgery
NCT00004921
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which chemotherapy regimen is most effective for ovarian epithelial cancer. PURPOSE: This randomized phase III trial is studying high-dose chemotherapy to see how well it works compared to standard chemotherapy in treating patients with stage III or stage IV ovarian epithelial cancer that has been remo... Read More
Gender:
FEMALE
Ages:
Between 18 years and 65 years
Trial Updated:
09/16/2013
Locations: Sozialmedizinisches Zentrum Ost - Donauspital, Vienna, Not set +16 locations
Conditions: Ovarian Cancer
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