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Paclitaxel Treatment Options in United Kingdom
A collection of 293 research studies where Paclitaxel is the interventional treatment. These studies are located in the United Kingdom . Paclitaxel is used for conditions such as Breast Cancer, Ovarian Cancer and Non-Small Cell Lung Cancer.
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Trastuzumab Deruxtecan (DS-8201a) Versus Investigator's Choice for HER2-low Breast Cancer That Has Spread or Cannot be Surgically Removed [DESTINY-Breast04]
Active Not Recruiting
This study will compare DS-8201a to physician choice standard treatment.
Participants must have HER2-low breast cancer that has been treated before.
Participants' cancer:
* Cannot be removed by an operation
* Has spread to other parts of the body
This study will compare DS-8201a to physician choice standard treatment.
Participants must have HER2-low breast cancer that has been treated before.
Participants' cancer:
* Cannot be removed by an operation
* Has spread to other parts of the body Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/09/2024
Locations: Ironwood Cancer & Research Centers - Chandler II, Chandler, Arizona +207 locations
Ironwood Cancer & Research Centers - Chandler II, Chandler, Arizona
Banner MD Anderson Cancer Center, Gilbert, Arizona
Cancer Treatment Centers of America at Western Regional Medical Center, Goodyear, Arizona
UCLA School of Medicine, Los Angeles, California
Stanford Cancer Institute, Palo Alto, California
Cancer Care Associates Medical Group, Inc. TORI, Redondo Beach, California
University of California at San Francisco (PARENT), San Francisco, California
Eastern Connecticut Hematology/Oncology Assoc., Norwich, Connecticut
Christiana Care Health Services, Inc., Newark, Delaware
Sylvester Comprehensive Cancer Center - Deerfield Beach, Boca Raton, Florida
Florida Cancer Specialists (South Region), Fort Myers, Florida
Memorial Healthcare System MRH Cancer Center, Hollywood, Florida
Orlando Health, Inc., Orlando, Florida
Moffitt Cancer Center -Tampa, Tampa, Florida
Cancer Treatment Centers of America-Georgia, Newnan, Georgia
University of Chicago Medical Center, Chicago, Illinois
Cancer Treatment Centers of America, Zion, Illinois
Cancer Center of Kansas, Wichita, Kansas
Touro Infirmary, New Orleans, Louisiana
Dana-Farber Cancer Institute, Boston, Massachusetts
Henry Ford Hospital, Detroit, Michigan
Saint Luke's Hospital of Kansas City, Kansas City, Missouri
Saint Barnabas Medical Center, Livingston, New Jersey
New York University Medical Center, New York, New York
Memorial Sloan Kettering Hospital, New York, New York
Weill Cornell Medicine Breast Center, New York, New York
The Cleveland Clinic Foundation, Cleveland, Ohio
Oregon Health & Science University, Portland, Oregon
Allegheny General Hospital, Pittsburgh, Pennsylvania
University of Pittsburgh Medical Center Health System, Pittsburgh, Pennsylvania
St Francis Hospital, Greenville, South Carolina
Brig Center for Cancer Care and Survivorship, Knoxville, Tennessee
Baptist Cancer Center, Memphis, Tennessee
Tennessee Oncology - Skyline Satellite, Nashville, Tennessee
BloomTrials Clinical Research, LLC, Dallas, Texas
The Methodist Hospital Research Institute, Houston, Texas
University of Texas M. D. Anderson Cancer Center - Investigational Cancer Therapeutics, Houston, Texas
Virginia Cancer Specialists, Fairfax, Virginia
Medizinische Universität Innsbruck, Innsbruck, Not set
Kepler Universitätsklinikum, Linz, Not set
LKH - Universitätsklinikum der PMU Salzburg, Salzburg, Not set
AKH - Medizinische Universität Wien (4305), Vienna, Not set
Klinikum Wels-Grieskirchen GmbH, Wels, Not set
Institut Jules Bordet, Bruxelles, Not set
Universitair Ziekenhuis Brussel, Bruxelles, Not set
Cliniques Universitaires Saint-Luc, Bruxelles, Not set
UZ Leuven, Leuven, Not set
Grand Hôpital de Charleroi, Loverval, Not set
CHU UCL Namur, Namur, Not set
Centre Hospitalier Wallonie picarde - Site IMC, Tournai, Not set
Tom Baker Cancer Center, Calgary, Alberta
Toronto Sunnybrook Hospital, Toronto, Ontario
McGill University - Dept. Oncology Clinical Research Program, Montréal, Quebec
Anhui Provincial Hospital, Hefei, Anhui
Cancer Hospital Chinese Academy of Medical Sciences, Beijing, Beijing
Chinese PLA General Hospital, Beijing, Beijing
Fuzhou General Hospital of Nanjing Military Area Command of Chinese PLA, Fuzhou, Fujian
Sun Yat-sen Memorial hospital, Sun Yat-sen University, Guangzhou, Guangdong
Harbin Medical University Cancer Hospital, Harbin, Heilongjiang
Hubei Cancer Hospital, Wuhan, Hubei
The Affiliated Drum Tower Hospital of Nanjing University, Nanjing, Jiangsu
The First Hospital of Jilin University, Chang chun, Jilin
Jilin Cancer Hospital, Chang chun, Jilin
Liaoning Cancer Hospital & Institute, Shenyang, Liaoning
General Hospital of Ningxia Medical University, Yinchuan, Ningxia
Linyi Cancer Hospital, Linyi, Shandong
Shanghai General Hospital, Shanghai, Shanghai
Fudan University Shanghai Cancer Center, Shanghai, Shanghai
West China Hospital, Sichuan University, Chengdu, Sichuan
Sir Run Run Shaw Hospital, Zhejiang University, School of Medicine, Hangzhou, Zhejiang
Zhejiang Cancer Hospital, Hangzhou, Zhejiang
Institut Paoli Calmettes, Marseille cedex 9, Bouches-du-Rhône
Centre François Baclesse, Caen, Calvados
CARIO - Centre Armoricain de Radiothérapie, Imagerie médicale et Oncologie, Plérin, Cotes d'Armor
CHU Brest - Hôpital Morvan, Brest Cedex, Finistere
Institut Bergonié, Bordeaux cedex, Gironde
Clinique Clementville, Montpellier, Herault
Institut Régional du Cancer de Montpellier, Montpellier, Herault
CRLCC Eugene Marquis, Rennes-cedex, Ille Et Vilaine
ICO - Site René Gauducheau, Saint-Herblain, Loire Atlantique
Centre Hospitalier Emile Roux, Le Puy-en-Velay, Loiret
ICO - Site Paul Papin, Angers Cedex 2, Maine Et Loire
Centre Hospitalier Valenciennes, Valenciennes, Nord
Hôpital Saint-Louis - Paris, Paris Cedex 10, Paris
Clinique Victor Hugo - Centre Jean Bernard, Le Mans Cedex 02, Sarthe
Institut Sainte Catherine, Avignon Cedex 9, Vaculuse
Hôpital d'Instruction des Armees Begin*, Saint Mande, Val De Marne
Institut Gustave Roussy, Villejuif cedex, Val De Marne
Institut Curie - site de Paris, Paris, Not set
Hopital Tenon, Paris, Not set
Universitaetsklinikum Heidelberg, Heidelberg, Baden Wuerttemberg
Klinikum der Universitaet Muenchen - Campus Grosshardern, Munich, Bayern
General Hospital of Athens "Alexandra", Athens, Not set
General Oncology Hospital of Kifissia " Agioi Anargyroi", Athens, Not set
Athens Medical Center, Athens, Not set
University General Hospital of Heraklion, Heraklion, Not set
University General Hospital of Larissa, Larissa, Not set
Bioclinic Thessaloniki, Thessaloníki, Not set
Euromedica General Clinic Thessaloniki, Thessaloníki, Not set
General Hospital Papageorgiou, Thessaloníki, Not set
Interbalkan Hospital of Thessaloniki, Thessaloníki, Not set
Del-pesti Centrumkorhaz - Orszagos Hematologiai es Infektologiai Intezet, Budapest, Not set
Orszagos Onkologiai Intezet, Budapest, Not set
Debreceni Egyetem, Debrecen, Not set
Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaza, Gyula, Not set
SzSzB Megyei Korhazak es Egyetemi Oktatokorhaz, Nyiregyhaza, Not set
Jasz-Nagykun-Szolnok Megyei Hetenyi Geza Korhaz-Rendelointezet, Szolnok, Not set
Rambam Health Care Center, Haifa, Not set
Shaare Zedek Medical Center, Jerusalem, Not set
Hadassah University Hospital - Ein Kerem, Jerusalem, Not set
Rabin Medical Center-Beilinson Campus, Petah tikva, Not set
Chaim Sheba Medical Center, Ramat Gan, Not set
Kaplan Medical Center, Rechovot, Not set
Ziv Medical Center, Safed, Not set
Tel Aviv Sourasky Medical Center, Tel Aviv, Not set
Azienda Ospedaliera Card. G. Panico, Tricase, Lecce
Azienda Socio Sanitaria Territoriale di Monza (Presidio San Gerardo), Monza, Milano
Istituto Clinico Humanitas, Rozzano, Milano
Ospedale Sacro Cuore Don Calabria, Negrar, Verona
Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi, Bologna, Not set
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (Presidio Spedali Civili), Brescia, Not set
Azienda Ospedaliera Univ. Policlinico Gaspare Rodolico, Catania, Not set
Azienda Ospedaliero Universitaria Mater Domini-Campus Universitario, Catanzaro, Not set
IEO Istituto Europeo di Oncologia, Milano, Not set
Istituto Nazionale Tumori Fondazione G. Pascale, Napoli, Not set
Ospedale degli Infermi, Rimini, Not set
Azienda Ospedaliera Universitaria Policlinico Tor Vergata, Roma, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Not set
Aichi Cancer Center Hospital, Nagoya, Aichi-Ken
National Cancer Center Hospital East, Kashiwa-shi, Chiba-Ken
NHO Shikoku Cancer Center, Matsuyama-shi, Ehime-Ken
NHO Kyushu Cancer Center, Fukuoka-shi, Fukuoka-Ken
Fukushima Medical University Hospital, Fukushima, Fukushima-Ken
Hiroshima City Hiroshima Citizens Hospital, Hiroshima-shi, Hiroshima-Ken
NHO Hokkaido Cancer Center, Sapporo-shi, Hokkaido
Hyogo College of Medicine Hospital, Nishinomiya-shi, Hyogo-Ken
Hakuaikai Sagara Hospital, Kagoshima, Kagoshima-Ken
Tokai University Hospital, Isehara, Kanagawa-Ken
Kanagawa Cancer Center, Yokohama, Kanagawa
NHO Osaka National Hospital, Osaka-shi, Osaka-Fu
Kindai University Hospital, Onohigashi, Osakasayama-shi
Saitama Cancer Center, Kitaadachi-gun, Saitama-Ken
Shizuoka Cancer Center, Sunto-gun, Shizuoka-Ken
Cancer Institute Hospital of JFCR, Koto-Ku, Tokyo-To
Toranomon Hospital, Minato-Ku, Tokyo-To
Showa University Hospital, Shinagawa-Ku, Tokyo-To
Chungbuk National University Hospital, Cheongju-si, Chungcheongbuk-do
National Cancer Center, Goyang-si, Gyeonggi-do
Inha University Hospital, Incheon, Gyeonggi-do
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do
Ajou University Hospital, Suwon, Gyeonggi-do
Kyungpook National University Chilgok Hospital, Daegu, Not set
Seoul National University Hospital, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
Hospital de Braga, Braga, Not set
Centro Hospitalar do Alto do Ave, EPE, Guimarães, Not set
Fundação Champalimaud, Lisboa, Not set
Centro Hospitalar de Lisboa Norte, E.P.E. - Hospital de Santa Maria, Lisboa, Not set
Unidade Local de Saúde de Matosinhos, EPE (Hospital Pedro Hispano), Matosinhos, Not set
Centro Hospitalar do Porto, E.P.E. - Hospital de Santo António, Porto, Not set
Instituto Português de Oncologia do Porto Francisco Gentil, EPE, Porto, Not set
Centro Hospitalar de Entre o Douro e Vouga, E.P.E - Hospital de São Sebastião, Santa Maria Da Feira, Not set
Centro Hospitalar Vila Nova de Gaia/Espinho, E.P.E, Vila Nova De Gaia, Not set
Centro Hospitalar de Trás-os-Montes e Alto Douro, EPE, Vila Real, Not set
FSBSI "Russian Oncological Scientific Center n.a. N.N. Blokhin", Moscow, Not set
SBIH of Moscow City "Moscow City Oncology Hospital №62" of Moscow Healthcare Departement, Moscow, Not set
SBIH of Yaroslavl Region "Regional Clinical Oncological Hospital", Yaroslavl, Not set
ICO l'Hospitalet - Hospital Duran i Reynals, L'Hospitalet De Llobregat, Barcelona
Hospital Universitario Donostia, San Sebastián, Guipuzcoa
Complejo Hospitalario Universitario A Coruña, A Coruña, La Coruña
Hospital Universitario de Canarias, San Cristobal de la Laguna, Tenerife
Hospital de Basurto, Bilbao, Vizcaya
Hospital del Mar, Barcelona, Not set
Hospital Quironsalud Barcelona, Barcelona, Not set
Hospital Universitari Vall d'Hebron, Barcelona, Not set
Hospital Clinic de Barcelona, Barcelona, Not set
MD Anderson Cancer Centre, Madrid, Not set
Hospital Ruber Internacional, Madrid, Not set
Hospital Universitario Ramon y Cajal, Madrid, Not set
Hospital Universitario Clinico San Carlos, Madrid, Not set
Hospital Clinico Universitario Virgen de la Victoria, Málaga, Not set
Hospital Universitario Virgen Macarena, Sevilla, Not set
Hospital Universitario Virgen del Rocio, Sevilla, Not set
Instituto Valenciano de Oncologia IVO, Valencia, Not set
Hospital General Universitario de Valencia, Valencia, Not set
Karolinska universitetssjukhuset - Solna, Solna, Not set
Länssjukhuset Sundsvall-Härnösand, Sundsvall, Not set
Akademiska Sjukhuset, Uppsala, Not set
Hirslanden Medical Center, Aarau, Not set
Universitaetsspital Basel, Basel, Not set
Kantonsspital Graubuenden, Chur, Not set
Centre Hospitalier Universitaire Vaudois, Lausanne, Not set
Kantonsspital St. Gallen, Saint Gallen, Not set
Kantonsspital Winterthur, Winterthur, Not set
Universitaetsspital Zuerich, Zürich, Not set
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Not set
National Cheng Kung University Hospital, Tainan, Not set
National Taiwan University Hospital, Taipei, Not set
Royal Cornwall Hospital, Truro, Cornwall
Queen Mary University of London, London, Greater London
University College London Hospitals, London, Greater London
Royal Free Hospital, London, Greater London
Western General Hospital, Edinburgh, Lothian Region
Nottingham University Hospitals City Campus, Nottingham, Nottinghamshire
Royal Surrey County Hospital, Guildford, Surrey
Conditions: Breast Cancer
Derazantinib Alone or in Combination With Paclitaxel, Ramucirumab or Atezolizumab in Gastric Adenocarcinoma
Terminated
The purpose of this study was to evaluate the efficacy of derazantinib monotherapy or derazantinib in combination with paclitaxel and ramucirumab in patients with gastric adenocarcinoma (GAC) i.e. with human epidermal growth factor receptor 2 (HER2)-negative adenocarcinoma of the stomach or gastro-esophageal junction harboring fibroblast growth factor receptor 2 (FGFR2) genetic aberrations (GA).
The purpose of this study was to evaluate the efficacy of derazantinib monotherapy or derazantinib in combination with paclitaxel and ramucirumab in patients with gastric adenocarcinoma (GAC) i.e. with human epidermal growth factor receptor 2 (HER2)-negative adenocarcinoma of the stomach or gastro-esophageal junction harboring fibroblast growth factor receptor 2 (FGFR2) genetic aberrations (GA). Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/06/2024
Locations: AdventHealth Cancer Institute, Orlando, Florida +80 locations
AdventHealth Cancer Institute, Orlando, Florida
Memorial Sloan Kettering Cancer Center, New York, New York
Hospital de Gastroenterologia Dr. Carlos Bonorino Udaondo, Ciudad Autonoma Buenos Aires, Not set
Fundación Favaloro para la Docencia e Investigación Médica, Ciudad Autonoma de Buenos Aires, Not set
Monash Medical Centre Clayton, Clayton, Not set
Peter MacCallum Cancer Centre, Melbourne, Not set
The Alfred Hospital, Prahran, Not set
UZA, Edegem, Not set
UZ Leuven, Leuven, Not set
AZ Delta, Menen, Not set
Liga Norte-Rio-Grandense Contra o Câncer, Natal, Rio Grande Do Norte
Fundação Doutor Amaral Carvalho, Jaú, Not set
Instituto Nacional de Câncer José Alencar Gomes da Silva, Rio De Janeiro, Not set
CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia, Santo André, Not set
Fundação Faculdade Regional de Medicina de São José do Rio Preto, São José Do Rio Preto, Not set
CeCim Biocinetic, Santiago, Region Met
Centro de Estudios Clínicos SAGA, Santiago, Not set
Instituto Clinico Oncologico, Temuco, Not set
Institut Sainte Catherine, Avignon, Not set
CHU Besançon - Hôpital Jean Minjoz, Besancon, Not set
Centre Georges François Leclerc, Dijon, Not set
Hôpital Saint-Louis, Paris, Not set
Hôpital Saint-Antoine, Paris, Not set
Institut Gustave Roussy, Villejuif, Not set
Universitaetsklinikum Ulm, Ulm, Baden Wuerttemberg
Medizinische Hochschule Hannover, Hannover, Niedersachsen
Universitaetsklinikum Carl Gustav Carus TU Dresden, Dresden, Sachsen
Staedtisches Klinikum Dresden Standort Dresden-Friedrichstadt, Dresden, Not set
Krankenhaus Nordwest GmbH, Frankfurt, Not set
Uniklinik Mainz, Mainz, Not set
Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi, Bologna, Not set
Azienda Ospedaliero Universitaria Mater Domini, Catanzaro, Not set
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Not set
IEO Istituto Europeo di Oncologia, Milano, Not set
Azienda Socio Sanitaria Territoriale Niguarda (Grande Ospedale Metropolitano Niguarda), Milano, Not set
IOV - Istituto Oncologico Veneto IRCCS, Padova, Not set
Istituto Clinico Humanitas, Rozzano, Not set
A.O.U. Senese Policlinico Santa Maria alle Scotte, Siena, Not set
National Cancer Center, Goyang-si, Not set
Chonnam National University Hwasun Hospital, Hwasun, Not set
Seoul National University Bundang Hospital, Seongnam, Not set
Seoul National University Hospital, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Not set
Ajou University Hospital, Suwon, Not set
Examen sp. z o.o., Skórzewo, Not set
Centrum Zdrowia MDM, Warszawa, Not set
Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy, Warszawa, Not set
Centrum Terapii Wspolczesnej J.M. Jasnorzewska sp. komandytowo-akcyjna, Łódź, Not set
SAIH "Republican Clinical Oncological Dispensary of the Ministry of Healthcare of Republic Tatarstan, Kazan, Not set
FSBSI "Russian Oncological Scientific Center n.a. N.N. Blokhin", Moscow, Not set
"VitaMed" LLC, Moscow, Not set
BHI of Omsk region "Clinical Oncology Dispensary", Omsk, Not set
FSBI "Clinical Research and Practical Center for specialized medical care (oncology)", Pesochnyy, Not set
Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Not set
FBI "Scientific Research Institute of Oncology n. a. N. N. Petrov", Saint Petersburg, Not set
Tomsk Research Instutite of Oncology, Tomsk, Not set
SBIH Republican Clinical Oncological Dispensary of the MoH of Republic Bashkortostan, Ufa, Not set
Hospital del Mar, Barcelona, Not set
Hospital Universitari Vall d'Hebron, Barcelona, Not set
Hospital Clinic de Barcelona, Barcelona, Not set
ICO l'Hospitalet - Hospital Duran i Reynals, L'Hospitalet de Llobregat, Not set
MD Anderson Cancer Centre, Madrid, Not set
Hospital Universitario Ramon y Cajal, Madrid, Not set
Centro Integral Oncologico Clara Campal, Madrid, Not set
Clinica Universidad de Navarra, Pamplona, Not set
Baskent University Adana Application and Research Center, Adana, Not set
Hacettepe University Medical Faculty, Ankara, Not set
Dr. Abdurrahman Yurtaslan Oncology Teaching and Research Hospital, Ankara, Not set
Ankara City Hospital, Ankara, Not set
Akdeniz University Medical Faculty, Antalya, Not set
Istanbul University Cerrahpasa - Cerrahpasa Medical Faculty, Istanbul, Not set
Istanbul Medeniyet Uni Goztepe Training&Res Hosp, Istanbul, Not set
Kocaeli Universitesi Tip Fakultesi, Kocaeli, Not set
Addenbrooke's Hospital, Cambridge, Not set
Ninewells Hospital, Dundee, Not set
Beatson West of Scotland Cancer Centre, Glasgow, Not set
University College London Hospitals, London, Not set
The Christie, Manchester, Not set
Royal Marsden Hospital- Sutton, Sutton, Not set
Conditions: Gastric Adenocarcinoma
A Study of Atezolizumab and Paclitaxel Versus Placebo and Paclitaxel in Participants With Previously Untreated Locally Advanced or Metastatic Triple Negative Breast Cancer (TNBC)
Completed
This Phase 3, multicenter, randomized, double-blind, placebo controlled study is designed to evaluate the efficacy and safety of atezolizumab (MPDL3280A, an anti-programmed death-ligand 1 \[PD-L1\] antibody) administered in combination with paclitaxel compared with placebo in combination with paclitaxel in participants with previously untreated, inoperable locally advanced or metastatic, centrally confirmed TNBC. Participants will be randomized in a 2:1 ratio to receive atezolizumab or placebo p... Read More
This Phase 3, multicenter, randomized, double-blind, placebo controlled study is designed to evaluate the efficacy and safety of atezolizumab (MPDL3280A, an anti-programmed death-ligand 1 \[PD-L1\] antibody) administered in combination with paclitaxel compared with placebo in combination with paclitaxel in participants with previously untreated, inoperable locally advanced or metastatic, centrally confirmed TNBC. Participants will be randomized in a 2:1 ratio to receive atezolizumab or placebo plus paclitaxel until disease progression or unacceptable toxicity or end of study, whichever occurs first (maximum up to approximately 40 months). In addition, the Sponsor may decide to terminate the study at any time. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/01/2024
Locations: Stanford Cancer Center, Stanford, California +160 locations
Stanford Cancer Center, Stanford, California
Florida Cancer Specialists; Department of Oncology, Fort Myers, Florida
Florida Cancer Specialist, North Region, Saint Petersburg, Florida
Northwest Georgia Oncology Centers PC - Marietta, Marietta, Georgia
HCA Midwest Health, Kansas City, Missouri
The Valley Hospital, Paramus, New Jersey
Magee-Woman's Hospital, Pittsburgh, Pennsylvania
Tennessee Oncology; Sarah Cannon Research Institute, Nashville, Tennessee
Centro Oncologico Riojano Integral (CORI), La Rioja, Not set
Santa Casa de Misericordia de Salvador, Salvador, BA
Centro de Pesquisas Clinicas em Oncologia - CPCO, Cachoeiro de Itapemirim, ES
Hospital Araujo Jorge; Departamento de Ginecologia E Mama, Goiania, GO
Hospital Nossa Senhora da Conceicao, Porto Alegre, RS
Hospital Sao Lucas - PUCRS, Porto Alegre, RS
Hospital Perola Byington, Sao Paulo, SP
Tom Baker Cancer Centre-Calgary, Calgary, Alberta
Cross Cancer Institute, Edmonton, Alberta
Kingston General Hospital, Kingston, Ontario
Grand River Hospital, Kitchener, Ontario
London Regional Cancer Centre, London, Ontario
Sunnybrook Odette Cancer Centre, Toronto, Ontario
McGill University; Glen Site; Oncology, Montreal, Quebec
Hopital du Saint Sacrement, Quebec City, Quebec
Centre Hospitalier Universitaire de Sherbrooke - Hopital Fleurimont, Sherbrooke, Quebec
Cancer Hospital Chinese Academy of Medical Sciences., Beijing, Not set
Beijing Union Hospital, Beijing, Not set
West China Hospital, Sichuan University; Department of Breast, Chengdu, Not set
Sun Yat-sen Memorial Hospital, Guangzhou, Not set
Harbin Medical University Cancer Hospital, Harbin, Not set
Shandong Cancer Hospital, Jinan, Not set
Jiangsu Province Hospital (the First Affiliated Hospital With Nanjing Medical University), Nanjing City, Not set
Jiangsu Cancer Hospital, Nanjing City, Not set
Fudan University Shanghai Cancer Center, Shanghai City, Not set
Shanghai Jiao Tong University School of Medicine (SJTUSM) - Ruijin Hospital (GuangCi Hospital), Shanghai, Not set
Liaoning cancer Hospital & Institute, Shenyang, Not set
Hebei Medical University Fourth Hospital;(Tumor Hospital of Hebei Province), Shijiazhuang, Not set
Tianjin Medical University Cancer Institute & Hospital, Tianjin, Not set
The Second Affiliated Hospital of Xi'an Jiao Tong University, Xi'an City, Not set
First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an, Not set
Zhejiang Cancer Hospital, Zhejiang, Not set
Henan Cancer Hospital, Zhengzhou, Not set
Clinical Hospital Centre Zagreb, Zagreb, Not set
Fakultni Nemocnice Hradec Kralove; Dept of Radiotherapy & Oncology, Hradec Kralove, Not set
Fakultni nemocnice Olomouc; Onkologicka klinika, Olomouc, Not set
Fakultni nemocnice Ostrava; Klinika onkologicka FNO a LF OU, Ostrava-Poruba, Not set
Fakultni Poliklinika Vseobecne Fakultni Niemocnice; Onkologicka Klinika, Praha 2, Not set
Clinique Sainte Catherine; Hopital De Semaine, Avignon, Not set
HOPITAL JEAN MINJOZ; Oncologie, Besancon, Not set
Polyclinique Bordeaux Nord Aquitaine, Bordeaux, Not set
Hopital Morvan, Brest, Not set
CHD Les Oudairies, La Roche Sur Yon, Not set
Centre Oscar Lambret; Senologie, Lille, Not set
Centre Leon Berard; Departement Oncologie Medicale, Lyon, Not set
Centre D'Oncologie de Gentilly; Oncology, Nancy, Not set
Hopital Caremeau; Hematologie Oncologie, Nimes, Not set
Hopital Tenon, Paris, Not set
Institut Curie; Oncologie Medicale, Paris, Not set
Hopital Saint Louis, Service D Oncologie Medicale, Paris, Not set
Ch Pitie Salpetriere; Oncologie Medicale, Paris, Not set
Centre Eugene Marquis; Service d'oncologie, Rennes, Not set
Centre Paul Strauss; Oncologie Medicale, Strasbourg, Not set
Institut Claudius Regaud; Departement Oncologie Medicale, Toulouse, Not set
Institut Gustave Roussy; Sitep, VILLEJUIF Cedex, Not set
Ambulantes Tumorzentrum Spandau; Dres. Benno Mohr und Uwe Peters, Berlin, Not set
Onkologische Schwerpunktpraxis Bielefeld, Bielefeld, Not set
Klinikum Essen-Mitte Ev. Huyssens-Stiftung / Knappschafts GmbH; Klinik für Senologie / Brustzentrum, Essen, Not set
HOPA im Struensee-Haus, Dres. Erik Engel, Wiebke Hollburg, Hamburg, Not set
Nationales Centrum für Tumorerkrankungen (NCT) ; Gyn. Onk. Frauenklinik; Uniklinikum Heidelberg, Heidelberg, Not set
St. Elisabeth Krankenhaus Köln GmbH; Gynäkologie und Geburtshilfe, Koeln, Not set
Universitätsmedizin Mainz; Klinik u. Poliklinik f. Geburtshilfe u. Frauenheilkunde, Mainz, Not set
OnkoNet Marburg GmbH, Marburg, Not set
Klinik & Poliklinik für Frauenheilkunde und Geburtshilfe, Campus Innenstadt, München, Not set
Gemeinschaftspraxis für Hämatologie und Onkologie, Münster, Not set
Klinikum Ernst von Bergmann; Frauenklinik, Potsdam, Not set
Dres. Helmut Forstbauer, Carsten Ziske und Kollegen; Onkologische Schwerpunktpraxis, Troisdorf, Not set
Universitätsklinik Tübingen; Frauenklinik, Tübingen, Not set
Anticancer Hospital Ag. Savas ; 2Nd Dept. of Oncology - Internal Medicine, Athens, Not set
ARETAIEION UNIVERSITY HOSPITAL; oncology unit, Athens, Not set
Agioi Anargyroi Cancer Hospital; 2Nd Oncology Dept., Kifisia, Not set
Papageorgiou General Hospital; Medical Oncology, Thessaloniki, Not set
Yashoda Hospital, Hyderabad, Andhra Pradesh
Dr. B L Kapur Memorial Hospital; BLK Cancer Centre, New Delhi, Delhi
Indraprastha Apollo Hospitals, New Delhi, Delhi
Rajiv Gandhi Cancer Inst.&Research Center; Medical Oncology, New Delhi, Delhi
Max Super Speciality Hospital; Medical Oncology, North WEST Delhi, Delhi
Manipal Hospital; Department of Oncology, Bangalore, Karnataka
Tata Memorial Hospital; Dept of Medical Oncology, Mumbai, Maharashtra
Jehangir Hospital, Pune, Maharashtra
Apollo Speciality Hospital, Chennai, Tamil NADU
Apollo Gleneagles Hospitals, Kolkata, WEST Bengal
TATA Medical Centre; Medical Oncology, Kolkata, WEST Bengal
MAX Balaji Hospital, Delhi, Not set
Hadassah Ein Karem Hospital; Oncology Dept, Jerusalem, Not set
Rabin MC; Davidof Center - Oncology Institute, Petach Tikva, Not set
Sheba Medical Center, Ramat Gan, Not set
Rambam Health Corporation; Oncology Institute, Rambam, Not set
Kaplan Medical Center, Rehovot, Not set
Tel Aviv Sourasky Medical Ctr; Oncology, Tel Aviv, Not set
Assaf Harofeh; Oncology, Zerifin, Not set
Fondazione Università G. D'Annunzio; Clinical Research Center (CRC); Centro Studi (CESI), Chieti, Abruzzo
Presidio Ospedaliero S. Giovanni Di Dio; U.O. Di Oncologia, Frattamaggiore, Campania
Azienda Ospedaliera Universitaria Federico II, Napoli, Campania
Istituto Nazionale Tumori Fondazione G. Pascale, Napoli, Campania
Azienda Ospedaliero - Universitaria di Modena Policlinico, Modena, Emilia-Romagna
Universita Campus Bio-Medico di Roma (UCBM), Roma, Lazio
IRCCS Istituto Regina Elena (IFO); Oncologia Medica B, Roma, Lazio
Azienda Policlinico Umberto I, Roma, Lazio
A.O. Universitaria S. Martino Di Genova, Genova, Liguria
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII (Presidio Papa Giovanni XXIII), Bergamo, Lombardia
Asst Degli Spedali Civili Di Brescia, Brescia, Lombardia
Hospital San Raffaele, Milano, Lombardia
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Lombardia
IEO Istituto Europeo di Oncologia;Divisione Oncologia Medica, Milano, Lombardia
IRCCS Istituto Clinico Humanitas; Oncologia, Rozzano (MI), Lombardia
Fondazione Del Piemonte Per L'oncologia IRCC Di Candiolo, Candiolo, Piemonte
Ospedale S. Vincenzo; Oncologia Medica, Taormina, Sicilia
Azienda Ospedaliero-Universitaria Careggi; SOD Radioterapia, Firenze, Toscana
Ospedale Civile; Unita Operativa Di Oncologia Medica, Livorno, Toscana
IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II, Padova, Veneto
Gunma Prefectural Cancer Center, Gunma, Not set
Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Not set
Sagara Hospital, Kagoshima, Not set
Kanagawa Cancer Center, Kanagawa, Not set
Tokai University Hospital, Kanagawa, Not set
Niigata Cancer Center Hospital, Niigata, Not set
Naha-nishi Clinic, Okinawa, Not set
Osaka International Cancer Institute, Osaka, Not set
Saitama Cancer Center, Saitama, Not set
The Cancer Institute Hospital of JFCR, Tokyo, Not set
Centre Hospitalier Universitaire Mohamed VI; Oncologie-Hématologie, Marrakech, Not set
Institut National D'oncologie Sidi Mohammed Ben Abdellah; Anatomopathologie, Rabat, Not set
Prof. Dr. I. Chiricuta Institute of Oncology, Cluj Napoca, Not set
Centrul de Oncologie Sfantul Nectarie, Craiova, Not set
Russian Oncology Research Center n.a. N.N. Blokhin, Moscow, Moskovskaja Oblast
Petrov Research Inst. of Oncology, Sankt Petersburg, Not set
King Fahad Specialist Hospital; Oncology, Dammam, Not set
International Medical Center (IMC), Jeddah, Not set
King Fahad Medical City; Gastroentrology, Riyadh, Not set
Narodny Onkologicky Ustav; Oddelenie klinickej onkologie A, Bratislava, Not set
POKO Poprad; Department of Oncology, Poprad, Not set
Wilgers Oncology Centre, Pretoria, Not set
Private Oncology Centre, Pretoria, Not set
Sandton Oncology Medical Group, Sandton, Not set
Complejo Hospitalario Universitario A Coruña (CHUAC); Servicio de Oncologia, A Coruña, LA Coruña
Hospital Clínic i Provincial; Servicio de Hematología y Oncología, Barcelona, Not set
Hospital Universitario de Fuenlabrada; Servicio de Oncologia, Madrid, Not set
Hospital Universitario Virgen Macarena; Servicio de Oncologia, Sevilla, Not set
Hospital Universitario Virgen del Rocio; Servicio de Oncologia, Sevilla, Not set
Adana Baskent University Medical Faculty; Oncology, Adana, Not set
Ankara Bilkent City Hospital, Ankara, Not set
Uludag University Medical Faculty; Internal Medicine, Bursa, Not set
Dicle Uni Medical Faculty; Internal Medicine, Diyarbakir, Not set
Trakya Universitesi Tip Fakultesi, Medikal Onkoloji Bilim Dali, Balkan Yerleskesi, Edirne, Not set
Izmir Ataturk Training and Research Hospital, Izmir, Not set
Kocaeli University Faculty of Medicine; Medical oncology, Izmit, Not set
Goztepe Prof.Dr. Suleyman Yalcin City Hospital; Clinical Oncology, Kadiköy, Not set
Guys and St Thomas NHS Foundation Trust, Guys Hospital, London, Not set
Christie Hospital, Manchester, Not set
Mount Vernon Cancer Centre, Northwood, Not set
K hospital, Hanoi, Not set
Hochiminh city oncology hospital, Hochiminh city, Not set
Conditions: Triple-Negative Breast Cancer
A Study of Trastuzumab Emtansine (T-DM1) Plus Pertuzumab/Pertuzumab Placebo Versus Trastuzumab [Herceptin] Plus a Taxane in Participants With Metastatic Breast Cancer (MARIANNE)
Completed
This randomized, 3-arm, multicenter, phase III study will evaluate the efficacy and safety of trastuzumab emtansine (T-DM1) with pertuzumab or trastuzumab emtansine (T-DM1) with pertuzumab-placebo (blinded for pertuzumab), versus the combination of trastuzumab (Herceptin) plus taxane (docetaxel or paclitaxel) in participants with HER2-positive progressive or recurrent locally advanced or previously untreated metastatic breast cancer. Participants will be randomized to 1 of 3 treatment arms (Arms... Read More
This randomized, 3-arm, multicenter, phase III study will evaluate the efficacy and safety of trastuzumab emtansine (T-DM1) with pertuzumab or trastuzumab emtansine (T-DM1) with pertuzumab-placebo (blinded for pertuzumab), versus the combination of trastuzumab (Herceptin) plus taxane (docetaxel or paclitaxel) in participants with HER2-positive progressive or recurrent locally advanced or previously untreated metastatic breast cancer. Participants will be randomized to 1 of 3 treatment arms (Arms A, B or C). Arm A will be open-label, whereas Arms B and C will be blinded. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/29/2024
Locations: Uni of Arkansas For Medical Sciences; Arkansas Cancer Research Center, Little Rock, Arkansas +256 locations
Uni of Arkansas For Medical Sciences; Arkansas Cancer Research Center, Little Rock, Arkansas
Scripps Cancer Center, La Jolla, California
University of California; Moores Cancer Center, La Jolla, California
Clnc L Trials & Rsch Assoc-Inc, Montebello, California
Southern California Kaiser Permanente, San Diego, California
Breastlink Medical Group Inc, Santa Ana, California
Kaiser Permanente; Oncology Clinical Trials, Vallejo, California
Smilow Cancer Hospital at Yale New Haven, New Haven, Connecticut
Innovative Medical Research of South Florida, Aventura, Florida
Northwest Oncology/ Hematology Assoc., Coral Springs, Florida
Florida Cancer Specialists; SCRI, Fort Myers, Florida
Mayo Clinic-Jacksonville, Jacksonville, Florida
Uni of Miami School of Medicine; Sylvester Comprehensive Cancer Center, Miami, Florida
University Cancer & Blood Center, LLC; Research, Athens, Georgia
Cancer Research Center of Hawaii; Clinical Sciences, Honolulu, Hawaii
Mountain States Tumor Inst., Boise, Idaho
Uni of Chicago, Chicago, Illinois
Decatur Memorial Hospital, Decatur, Illinois
Ingalls Memorial Hospital, Harvey, Illinois
Loyola University Med Center, Maywood, Illinois
Illinois Cancer Care, Peoria, Illinois
Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana
Horizon Oncology Research, Inc., Lafayette, Indiana
James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky
New England Cancer Specialists, Scarborough, Maine
Anne Arundel Health System Research Instit-Annapolis Oncology Ctr, Annapolis, Maryland
Boston Medical Center, Boston, Massachusetts
Spectrum Health Grand Rapids, Grand Rapids, Michigan
University of Minnesota., Minneapolis, Minnesota
Mayo Clinic Rochester, Rochester, Minnesota
St. John'S Mercy Medical Center; David C. Pratt Cancer Center, Saint Louis, Missouri
Mercy Clinic Cancer & Hematology, Springfield, Missouri
Dartmouth Hitchcock Med Center, Lebanon, New Hampshire
Hackensack Uni Medical Center; Northern Nj Cancer Center, Hackensack, New Jersey
Cancer Inst. of New Jersey, New Brunswick, New Jersey
San Juan Oncology Associates, Farmington, New Mexico
Queens Medical Associates, Fresh Meadows, New York
Queens Hospital Center, Jamaica, New York
Arena Oncology Associates, Lake Success, New York
Icahn School of Medicine at Mount Sinai, New York, New York
Weill Medical College of Cornell Uni, New York, New York
Carolinas Hem-Oncology Assoc, Charlotte, North Carolina
Carolina Oncology Specialists, PA - Hickory, Hickory, North Carolina
Marion L. Shepard Cancer Center, Washington, North Carolina
Sanford Roger Maris Cancer Center, Fargo, North Dakota
Oncology Hematology Care - SCRI, Cincinnati, Ohio
Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania
Charleston Oncology, P .A, Charleston, South Carolina
Medical University of SC (MUSC), Charleston, South Carolina
South Carolina Oncology Associates - SCRI, Columbia, South Carolina
Avera Cancer Institute, Sioux Falls, South Dakota
SCRI Tennessee Oncology Chattanooga, Chattanooga, Tennessee
West Clinic, Germantown, Tennessee
Tennessee Onc., PLLC - SCRI, Nashville, Tennessee
Vanderbilt-Ingram Cancer Ctr, Nashville, Tennessee
The Don & Sybil Harrington Cancer Center; Department of Clinical Research, Amarillo, Texas
Uni of Texas Southwestern Medical Center, Dallas, Texas
Uni of Texas - Md Anderson Cancer Center; Dept of Breast Medical Oncology, Houston, Texas
Northern Utah Associates, Ogden, Utah
The Providence Regional Medical Center Everett, Everett, Washington
University of Washington, Seattle, Washington
Northwest Medical Specialties, Tacoma, Washington
Fundación Investigar, Buenos Aires, Not set
Centro Medico San Roque, San Miguel de Tucuman, Not set
Mater Misericordiae Hospital; Chemotherapy Cottage, Sydney, New South Wales
Calvary Mater Newcastle; Medical Oncology, Waratah, New South Wales
Wesley Medical Centre; Clinic For Haematology and Oncology, Auchenflower, Queensland
Royal Adelaide Hospital; Oncology, Adelaide, South Australia
Peter Maccallum Cancer Institute; Medical Oncology, Melbourne, Victoria
Lkh Salzburg - Univ. Klinikum Salzburg; Iii. Medizinische Abt., Salzburg, Not set
Medizinische Universität Wien; Univ.Klinik für Innere Medizin I - Abt. für Onkologie, Wien, Not set
Oncology Consultants Limited, Nassau, Not set
Cliniques Universitaires St-Luc, Bruxelles, Not set
Clinique Ste-Elisabeth, Namur, Not set
Sint Augustinus Wilrijk, Wilrijk, Not set
University Clinical Centre of the Republic of Srpska, Banja Luka, Not set
Clinic of Oncology, University Clinical Center Sarajevo, Sarajevo, Not set
*X*Instituto Nacional do Cancer - INCA, Rio de Janeiro, RJ
Liga Norte Riograndense Contra O Câncer, Natal, RN
Hospital Nossa Senhora da Conceicao, Porto Alegre, RS
Clinica de Oncologia de Porto Alegre - CliniOnco, Porto Alegre, RS
Hospital Sao Lucas - PUCRS, Porto Alegre, RS
Clinica de Neoplasias Litoral, Itajai, SC
Instituto do Cancer do Estado de Sao Paulo - ICESP, Sao Paulo, SP
Hospital Perola Byington, Sao Paulo, SP
Cross Cancer Institute; Clinical Trials, Edmonton, Alberta
North York General Hospital, Toronto, Ontario
Cuse - Centre Universitaire De Sante; Site Fleurimont, Sherbrooke, Quebec
CHU de Québec ? Hôpital du Saint-Sacrement / ONCOLOGY, Quebec, Not set
Clinica del Country, Bogota, Not set
Instituto Colombiano Para El Avance De La Medicina: Icamedic, Bucaramanga, Not set
Centro Medico Imbanaco, Cali, Not set
Instituto Cancerologico de Nariño, Pasto, Not set
Masarykuv onkologicky ustav, Brno, Not set
Fakultni nemocnice Olomouc; Onkologicka klinika, Olomouc, Not set
Fakultni Poliklinika Vseobecne Fakultni Niemocnice; Onkologicka Klinika, Praha 2, Not set
Fakultni Nemocnice Na Bulovce; Ustav Radiacni Onkologie, Praha, Not set
Vejle Sygehus; Onkologisk Afdeling, Vejle, Not set
HOPITAL JEAN MINJOZ; Oncologie, Besancon, Not set
Centre Jean Perrin; Hopital De Jour, Clermont Ferrand, Not set
Centre Oscar Lambret; Senologie, Lille, Not set
Institut Paoli Calmettes; Oncologie Medicale, Marseille, Not set
Institut régional du Cancer Montpellier, Montpellier, Not set
Centre D'Oncologie de Gentilly; Oncology, Nancy, Not set
Institut Curie; Oncologie Medicale, Paris, Not set
Hopital Saint Louis; Service Onco Thoracique, Paris, Not set
HOPITAL TENON; Cancerologie Medicale, Paris, Not set
Chu La Miletrie; Radiotherapie, Poitiers, Not set
Centre Rene Huguenin; ONCOLOGIE GENETIQUE, Saint Cloud, Not set
Institut de Cancerologie de La Loire; Radiotherapie, St Priest En Jarez, Not set
Klinikum Essen-Mitte Ev. Huyssens-Stiftung / Knappschafts GmbH; Klinik für Senologie / Brustzentrum, Essen, Not set
Universitätsklinikum Halle (Saale); Universitätsklinik Und Poliklinik Für Gynäkologie, Halle, Not set
Facharztzentrum Eppendorf, Studien GbR, Hamburg, Not set
MVZ Onko Medical GmbH Hannover, Ralf Lohse (Geschäftsführer), Hannover, Not set
Nationales Centrum für Tumorerkrankungen (NCT) ; Gyn. Onk. Frauenklinik; Uniklinikum Heidelberg, Heidelberg, Not set
Universitätsklinikum Magdeburg; Frauenheilkunde & Geburtshilfe, Magdeburg, Not set
Universitätsmedizin Mainz; Klinik u. Poliklinik f. Geburtshilfe u. Frauenheilkunde, Mainz, Not set
Mühlenkreiskliniken; Johannes Wesling Klinikum Minden; Klinik für Frauenheilkunde und Geburtshilfe, Minden, Not set
Rotkreuzklinikum München; Frauenklinik, Muenchen, Not set
Klinikum Mutterhaus der Borromaeerinnen gGmbH; Haematologie/Onkologie, Trier, Not set
Alexandras General Hospital of Athens; Oncology Department, Athens, Not set
Univ General Hosp Heraklion; Medical Oncology, Heraklion, Not set
University Hospital of Larissa; Oncology, Larissa, Not set
Grupo Angeles, Guatemala City, Not set
Centro Oncológico Sixtino / Centro Oncológico SA, Guatemala, Not set
Szent Margit Hospital; Dept. of Oncology, Budapest, Not set
Semmelweis Egyetem Onkologiai Központ, Budapest, Not set
Semmelweis Egyetem Aok; Iii.Sz. Belgyogyaszati Klinika, Budapest, Not set
Pécsi Tudományegyetem; Klinikai Központ Onkoterápiás Intézet, Pécs, Not set
Campus Universitario S.Venuta; Centro Oncologico T.Campanella, Catanzaro, Calabria
IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola; Oncologia Medica, Meldola, Emilia-Romagna
A.O. Universitaria Policlinico Di Modena; Ematologia, Modena, Emilia-Romagna
Arcispedale Santa Maria Nuova; Oncologia, Reggio Emilia, Emilia-Romagna
Ospedale Degli Infermi; Divisione Di Oncologia, Rimini, Emilia-Romagna
Azienda Ospedaliero-Universitaria Dipartimento Interaziendale Di Oncologia, Udine, Friuli-Venezia Giulia
Istituto Europeo Di Oncologia, Milano, Lombardia
Fondazione Salvatore Maugeri, Pavia, Lombardia
IRCCS Istituto Clinico Humanitas; Oncologia, Rozzano (MI), Lombardia
Centro Catanese Di Oncologia; Oncologia Medica, Catania, Sicilia
Ospedale Papardo- Piemonte;Oncologia Medica, Messina, Sicilia
Ospedale Misericordia E Dolce; Oncologia Medica, Prato, Toscana
Azienda Ospedaliera Di Perugia Ospedale s. Maria Della Misericordia; Oncologia Medica, Perugia, Umbria
Aichi Cancer Center Hospital, Breast Oncology, Aichi, Not set
Natl Hosp Org Shikoku; Cancer Ctr, Surgery, Ehime, Not set
National Hospital Organization Kyushu Cancer Center;Breast Oncology, Fukuoka, Not set
Gifu University Hospital; Digestive Surgery, Gifu, Not set
Hiroshima University Hospital; Breast Surgery, Hiroshima, Not set
National Hospital Organization Hokkaido Cancer Center; Breast Surgery, Hokkaido, Not set
Hyogo College Of Medicine; Breast And Endocrine Surgery, Hyogo, Not set
Hyogo Cancer Center; Breast Surgery, Hyogo, Not set
Kanazawa University Hospital; Breast Oncology, Ishikawa, Not set
Iwate Med Univ School of Med; Surgery, Iwate, Not set
Sagara Hospital; Breast Surgery, Kagoshima, Not set
Tokai University Hospital, Breast Surgery, Kanagawa, Not set
Kumamoto University Hospital; Breast and Endocrine Surgery, Kumamoto, Not set
Kumamoto City Hospital, Breast and Endocrine Surgery, Kumamoto, Not set
Kyoto University Hospital; Breast Surgery, Kyoto, Not set
Tohoku University Hospital; General Surgery, Miyagi, Not set
Niigata Cancer Ctr Hospital; Breast Surgery, Niigata, Not set
Kawasaki Medical School Hospital; Breast and Thyroid Surgery, Okayama, Not set
National Hospital Organization Osaka National Hospital; Breast Surgery, Osaka, Not set
Osaka University Hospital; Breast and Endocrine Surgery, Osaka, Not set
Saitama Medical University International Medical Center; Medical Oncology, Saitama, Not set
Saitama Cancer Center, Breast Oncology, Saitama, Not set
Shizuoka Cancer Center; Breast Surgery, Shizuoka, Not set
Shizuoka General Hospital; Breast Surgery, Shizuoka, Not set
National Cancer Center Hospital; Medical Oncology, Tokyo, Not set
Toranomon Hospital; Breast and Endocrine Surgery, Tokyo, Not set
The Cancer Inst. Hosp. of JFCR; Breast Oncology Center, Tokyo, Not set
Tokyo Medical Uni. Hospital; Breast Oncology, Tokyo, Not set
Seoul National University Bundang Hospital; Hematology Medical Oncology, Gyeonggi-do, Not set
Seoul National Uni Hospital; Dept. of Internal Medicine/Hematology/Oncology, Seoul, Not set
Samsung Medical Centre; Division of Hematology/Oncology, Seoul, Not set
Asan Medical Center, Uni Ulsan Collegemedicine; Dept.Internal Medicine / Divisionhematology/Oncology, Seoul, Not set
Korea University Guro Hospital; Oncology, Seoul, Not set
Pantai Hospital Kuala Lumpur; Dept of Oncology & Radiotherapy, Kuala Lumpur, FED. Territory OF Kuala Lumpur
Beacon International Specialist Centre, Petaling Jaya, Selangor, Selangor
Sunway Medical Centre, Selangor, Not set
Centro de Investigacion; Clinica Del Pacifico, Acapulco, Guerrero
Centro Universitario Contra El Cancer, Monterrey, Nuevo LEON
Oaxaca Site Management Organization, Oaxaca de Juárez, Oaxaca
Hospital Privado San Jose; Oncologia, Obregon, Sonora
Centenario Hospital Miguel Hidalgo, Aguascalientes, Not set
Centro Oncológico Estatal; ISSSEMYM Oncología, Toluca, Not set
Auckland city hospital; Auckland Regional Cancer Centre and Blood Service, Auckland, Not set
Waikato Hospital; Regional Cancer Center, Hamilton, Not set
Private Health Organization Acibadem Sistina Hospital, Skopje, Not set
The Panama Clinic, Panama, Not set
Hospital Nacional Carlos Alberto Seguin Escobedo-Essalud; Oncology & Haemathology, Arequipa, Not set
Hospital Nacional Edgardo Rebagliati Martins; Oncologia, Lima, Not set
Unidad de Investigacion Oncologia Clinica ? Piura; Unidad de Oncología Clínica, Piura, Not set
Cebu Cancer Institute; Perpetual Succour Hospital, Cebu City, Not set
Cardinal Santos Medical Center, San Juan, Not set
Centrum Onkologii;Im. Franciszka Lukaszczyka;Onkologii, Bydgoszcz, Not set
Medical University of Gdansk, Gdansk, Not set
Centrum Onkologii, Instytut, Klinika Chemioterapii; Oddzial Chemoterapii, Krakow, Not set
COZL Oddzial Onkologii Klinicznej z pododdzialem Chemioterapii Dziennej, Lublin, Not set
Cent.Onkologii-Instytut im. M. S-Curie, Klinika Now. Piersi i Chirurgii Rekon, Warszawa, Not set
IPO do Porto; Servico de Oncologia Medica, Porto, Not set
Coltea Hospital; Oncology, Bucharest, Not set
Prof. Dr. I. Chiricuta Institute of Oncology, Cluj Napoca, Not set
Cluj Clinical County Hospital; Oncology Dept, Cluj-Napoca, Not set
Moscow city oncology hospital; #62 of Moscow Healthcare Department, Moscow, Moskovskaja Oblast
Blokhin Cancer Research Center; Combined Treatment, Moskva, Moskovskaja Oblast
Ryazan State Medical University Named after I.P.Pavlov, Ryazan, Rjazan
State Budget Institution of Healthcare of Stavropol region Pyatigorsk Oncology Dispensary, Pyatigorsk, Stavropol
Clinical Oncology Dispensary of Ministry of Health of Tatarstan, Kazan, Tatarstan
Ivanovo Regional Oncology Dispensary, Ivanovo, Not set
SBI of Healthcare Samara Regional Clinical Oncology Dispensary, Samara, Not set
SBI of Healthcare of Stavropol region Stavropol Regional Clinical Oncology Dispensary, Stavropol, Not set
Tula Regional Oncology Dispensary, Tula, Not set
GUZ Vladimir Regional Clinical Oncological Dispensary, Vladimir, Not set
Hospital General Universitario de Elche; Servicio de Oncologia, Elche, Alicante
Hospital Univ Vall d'Hebron; Servicio de Oncologia, Sant Andreu de La Barca, Barcelona
Complejo Hospitalario Universitario de Santiago (CHUS) ; Servicio de Oncologia, Santiago de Compostela, LA Coruña
Hospital del Mar; Servicio de Oncologia, Barcelona, Not set
Complejo Hospitalario de Jaen-Hospital Universitario Medico Quirurgico; Servicio de Oncologia, Jaen, Not set
Complejo Hospitalario Universitario A Coruña (CHUAC, Materno Infantil), Oncología, La Coruña, Not set
Hospital General Universitario Gregorio Marañon; Servicio de Oncologia, Madrid, Not set
Hospital Universitario 12 de Octubre; Servicio de Oncologia, Madrid, Not set
Hospital Universitario La Paz; Servicio de Oncologia, Madrid, Not set
Hospital Clinico Universitario Virgen de la Victoria; Servicio de Oncologia, Malaga, Not set
Hospital Clinico Universitario de Valencia; Servicio de Onco-hematologia, Valencia, Not set
Skånes Universitetssjukhus; Kliniska Forskningsenheten Onkologimottagning medicinsk behandling, Malmö, Not set
Kantonsspital Baden; Medizinische Klinik, Onkologie, Baden, Not set
Universitaetsspital Basel; Onkologie, Basel, Not set
Kantonsspital Graubünden Medizin Onkologie; Onkologie und Hämatologie, Chur, Not set
Changhua Christian Hospital; Hematology-Oncology, Changhua, Not set
Kaohsiung Medical Uni Chung-Ho Hospital; Dept of Surgery, Kaohsiung, Not set
National Taiwan Uni Hospital; Dept of Oncology, Taipei, Not set
Tri-Service General Hospital; Hematology and Oncology, Taipei, Not set
National Cancer Inst., Bangkok, Not set
Rajavithi Hospital; Division of Medical Oncology, Bangkok, Not set
Ramathibodi Hospital; Dept of Med.-Div. of Med. Onc, Bangkok, Not set
Faculty of Med. Siriraj Hosp.; Med.-Div. of Med. Oncology, Bangkok, Not set
Maharaj Nakorn Hospital; Internal Medicine, Chiang Mai, Not set
Songklanagarind Hospital; Department of Oncology, Songkhla, Not set
Baskent University Adana Dr. Turgut Noyan Practice and Research Hospital; Medical Oncology, Adana, Not set
Cukurova Uni Faculty of Medicine; Medical Oncology, Adana, Not set
Gazi Uni Medical Faculty Hospital; Oncology Dept, Ankara, Not set
Ege Uni Medical Faculty Hospital; Oncology Dept, Izmir, Not set
Bristol Haematology and Oncology centre, Bristol, Not set
Cambridge University Hospitals NHS Foundation Trust, Cambridge, Not set
Royal Cornwall Hospital; Dept of Clinical Oncology, Cornwall, Not set
The Beatson West of Scotland Cancer Centre; Cancer Clinical Trials Unit, Glasgow, Not set
Leicester Royal Infirmary; Dept. of Medical Oncology, Leicester, Not set
Royal Free Hospital; Dept of Oncology, London, Not set
Guys Hospital; Management Offices, London, Not set
Royal Marsden Hospital; Dept of Med-Onc, London, Not set
Christie Hospital; Breast Cancer Research Office, Manchester, Not set
Nottingham City Hospital; Oncology, Nottingham, Not set
Peterborough City Hospital; Oncology Ward, Peterborough, Not set
Queen Alexandra Hospital, Portsmouth, Portsmouth, Not set
Weston Park Hospital; Cancer Clinical Trials Centre, Sheffield, Not set
Southampton General Hospital; Somers Cancer Research Building, Southampton, Not set
Uni Hospital of North Staffordshire; Staffordshire Oncology Centre, Stoke-on-Trent, Not set
Royal Marsden Hospital; Dept of Medical Oncology, Sutton, Not set
Conditions: Breast Cancer
A Study of Ipatasertib in Combination With Atezolizumab and Paclitaxel as a Treatment for Participants With Locally Advanced or Metastatic Triple-Negative Breast Cancer
Completed
This study evaluated the efficacy and safety of ipatasertib in combination with atezolizumab and paclitaxel in locally advanced or metastatic Triple-Negative Breast Cancer (TNBC) previously untreated in this setting.
This study evaluated the efficacy and safety of ipatasertib in combination with atezolizumab and paclitaxel in locally advanced or metastatic Triple-Negative Breast Cancer (TNBC) previously untreated in this setting. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: USA Mitchell Cancer Institute, Mobile, Alabama +181 locations
USA Mitchell Cancer Institute, Mobile, Alabama
Highlands Oncology Group, Springdale, Arkansas
UCLA, Los Angeles, California
Kaiser Permanente-SCPMG; Oncology Research, San Diego, California
Stanford Cancer Center, Stanford, California
Kaiser Permanente - Franklin, Denver, Colorado
Stamford Hospital; BCC, MOHR, Stamford, Connecticut
Holy Cross Hospital, Fort Lauderdale, Florida
Memorial Healthcare System - Memorial Regional Hospital, Hollywood, Florida
Memorial Cancer Institute at Memorial West, Pembroke Pines, Florida
Winship Cancer Institute, Atlanta, Georgia
Nancy N. and J.C. Lewis Cancer & Research Pavillion -St. Josephs / Candler Health System-CCD PRIME, Savannah, Georgia
Rush University, Chicago, Illinois
Ochsner Clinic Foundation, Baton Rouge, Louisiana
Ochsner Health System, New Orleans, Louisiana
University of Maryland Medical Center, Baltimore, Maryland
Mercy Medical Center, Baltimore, Maryland
Medstar Franklin Square Medical Center, Baltimore, Maryland
St. Joseph Mercy Hospital; Cancer Care Center., Ann Arbor, Michigan
Henry Ford Health System, Detroit, Michigan
Jackson Oncology Associates, PLLC, Jackson, Mississippi
CHI Health Saint Francis; Oncology, Grand Island, Nebraska
Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire
Hackensack Univ Med Ctr, Hackensack, New Jersey
Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina
Kaiser Permanente - Portland, Portland, Oregon
Oregon Health and Science University, Portland, Oregon
Charleston Oncology, P .A, Charleston, South Carolina
Greenville Health System; Cancer Center, Greenville, South Carolina
The West Clinic; West Cancer Center, Germantown, Tennessee
Vanderbilt Univ Medical Ctr, Nashville, Tennessee
Fundación CENIT para la Investigación en Neurociencias, Buenos Aires, Not set
Inst. Angel Roffo; Haematology, Buenos Aires, Not set
Hospital Britanico, Ciudad Autonoma Bs As, Not set
Instituto Medico Rio Cuarto, Cordoba, Not set
Centro Oncologico Riojano Integral (CORI), La Rioja, Not set
Fundacion Scherbovsky, Mendoza, Not set
Macquarie University Hospital, Macquarie Park, New South Wales
Mid North Coast Cancer Institute, Port Macquarie, New South Wales
Royal North Shore Hospital; Department of Medical Oncology, St Leonards, New South Wales
Calvary Mater Newcastle; Medical Oncology, Waratah, New South Wales
Princess Alexandra Hospital, Woolloongabba, Queensland
Adelaide Cancer Centre, Kurralta Park, South Australia
Monash Health Monash Medical Centre, Clayton, Victoria
Peter MacCallum Cancer Centre; Medical Oncology, Melbourne, Victoria
Sunshine Hospital; Oncology Research, St Albans, Victoria
St John of God Hospital; Bendat Cancer Centre, Subiaco, Western Australia
Tiroler Landeskrankenanstalten Ges.M.B.H.; Abt. Für Gynäkologie, Innsbruck, Not set
Ordensklinikum Linz Barmherzige Schwestern; Interne 1 - Hämato-Onkologie, Linz, Not set
Uniklinikum Salzburg, LKH; Univ.Klinik f. Innere Medizin III der PMU, Salzburg, Not set
Medizinische Universität Wien; Univ.Klinik für Innere Medizin I, Wien, Not set
AZ Maria Middelares, Gent, Not set
Jessa Zkh (Campus Virga Jesse), Hasselt, Not set
Hospital Sao Rafael - HSR, Salvador, BA
Hospital das Clinicas - UFRGS, Porto Alegre, RS
Clinica de Pesquisa e Centro de Estudos em Oncologia Ginecologica e Mamaria Ltda, Sao Paulo, SP
Núcleo de Pesquisa São Camilo; ONCOLOGIA CLINICA / QUIMIOTERAPIA, Sao Paulo, SP
MHAT Nadezhda, Sofia, Not set
Cross Cancer Institute ; Dept of Medical Oncology, Edmonton, Alberta
Fraser Valley Centre British Columbia Cancer Agency, Surrey, British Columbia
Cancer Care Manitoba, Winnipeg, Manitoba
Royal Victoria Hospital, Barrie, Ontario
The Ottawa Hospital Cancer Centre, Ottawa, Ontario
McGill University; Glen Site; Oncology, Montreal, Quebec
Jewish General Hospital; Research Unit, Montréal, Quebec
Hopital du Saint Sacrement, Quebec City, Quebec
Clinica del Country, Bogota, Not set
Oncólogos de Occidente, Pereira, Not set
Clinica CIMCA, San José, Not set
Masaryk?v onkologický ústav; Klinika komplexní onkologické pé?e, Brno, Not set
Fakultni nemocnice Olomouc; Onkologicka klinika, Olomouc, Not set
Herlev Hospital; Afdeling for Kræftbehandling, Herlev, Not set
Odense Universitetshospital, Onkologisk Afdeling R, Odense C, Not set
Docrates Cance Center, Helsinki, Not set
KYS Sadesairaala; Syopatautien poliklinikka, Kuopio, Not set
VAASAN KESKUSSAIRAALA; Onkologian poliklinikka, Vaasa, Not set
Centre Eugene Marquis; Service d'oncologie, Rennes, Not set
Agioi Anargyroi Cancer Hospital; 2Nd Oncology Dept., Kifisia, Not set
Euromedical General Clinic of Thessaloniki; Oncology Department, Thessaloniki, Not set
Queen Mary Hospital; Dept of Medicine, Hong Kong, Not set
Tuen Mun Hospital; Clinical Onc, Hong Kong, Not set
Prince of Wales Hospital; Department of Clinical Onocology, Shatin, Not set
Sahyadri Super Specialty Hospital Hadapsar, Pune, Maharashtra
Shaare Zedek Medical Center, Jerusalem, Not set
Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione G. Pascale, Napoli, Campania
IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola; Oncologia Medica, Meldola, Emilia-Romagna
ASU FC S. M. DELLA MISERICORDIA; Oncologia, Udine, Friuli-Venezia Giulia
ASST DEGLI SPEDALI CIVILI DI BRESCIA; Oncologia Medica, Brescia, Lombardia
ASST DI LECCO; Oncologia Medica, Lecco, Lombardia
IRCCS Istituto Clinico Humanitas; Oncologia, Rozzano (MI), Lombardia
Ospedale Civile; Unita Operativa Di Oncologia Medica, Livorno, Toscana
IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II, Padova, Veneto
Aichi Cancer Center Hospital, Aichi, Not set
Fukushima Medical University Hospital, Fukushima, Not set
Gunma Prefectural Cancer Center, Gunma, Not set
Hiroshima University Hospital, Hiroshima, Not set
Kanagawa Cancer Center, Kanagawa, Not set
Kumamoto Shinto General Hospital, Kumamoto, Not set
Okayama University Hospital, Okayama, Not set
Osaka International Cancer Institute, Osaka, Not set
Kyungpook National University Medical Center, Daegu, Not set
National Cancer Center, Goyang-si, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Seoul St Mary's Hospital, Seoul, Not set
Investigacion Oncofarmaceutica, La Paz, BAJA California SUR
Health Pharma Professional Research, Cdmx, Mexico CITY (federal District)
Christus Muguerza Clinica Vidriera, Monterrey, Nuevo LEON
Auckland City Hospital, Cancer and Blood Research, Auckland, Not set
Tauranga Hospital, Clinical Trials Unit; BOP Clinical School, Tauranga, Not set
Wellington Regional Hospital; Clinical Trials Unit, Wellington, Not set
Centro Medico Monte Carmelo, Arequipa, Not set
Instituto Regional de Enfermedades Neoplasicas, Arequipa, Not set
Unidad de Investigación Oncologica; Hospital Nacional Daniel Alcides Carrion, Lima, Not set
Clínica San Gabriel; Unidad de Investigación Oncológica de la Clínica San Gabriel, Lima, Not set
Hospital Arzobispo Loayza, Lima, Not set
Oncosalud Sac; Oncología, Lima, Not set
Instituto Nacional de Enfermedades Neoplasicas, Lima, Not set
Clinica Ricardo Palma, San Isidro, Not set
Instyt. Centrum Zdrowia Matki Polki; Klinika Chirurgii Onk. Chorób Piersi z Podod. Onko Klinicznej, ?ód?, Not set
Narodowy Inst.Onkol.im.Sklodowskiej-Curie Panstw.Inst.Bad Gliwice; Centr.Diagn.i Lecz.Chor.Piersi, Gliwice, Not set
Szpital Uniwersytecki w Krakowie, Oddzia? Kliniczny Kliniki Onkologii, Kraków, Not set
Wielkopolskie Centrum Onkologii, Poznan, Not set
Narodowy Instytut Onkologii im. M.Sklodowskiej-Curie; Klinika Nowotworow Piersi i Chirurgii Rekonstr, Warszawa, Not set
Hospital da Luz; Departamento de Oncologia Medica, Lisboa, Not set
Hospital de Santa Maria; Servico de Oncologia Medica, Lisboa, Not set
Hospital Beatriz Angelo; Departamento de Oncologia, Loures, Not set
Centro Hospitalar do Porto ? Hospital de Santo António; Oncologia, Porto, Not set
IPO do Porto; Servico de Oncologia Medica, Porto, Not set
Oncology Center Sf. Nectarie, Craiova, Not set
Arkhangelsk Regional Clinical Oncology Dispensary, Arkhangelsk, Arhangelsk
University ?linic of headaches, Moscow, Moskovskaja Oblast
P.A. Gertsen Cancer Research Inst. ; Chemotherapy Dept, Moscow, Moskovskaja Oblast
SBIH "Moscow Clinical Scientific and Practical Center named after A.S. Loginov of DHM", Moskva, Moskovskaja Oblast
Fed State Budgetary Inst "N.N. Blokhin Med Center of Oncology" MHRF, Moskva, Moskovskaja Oblast
FSAI Treatment and rehabilitation Centre Ministry of Health; Clinical research and chemotherapy., Moskva, Moskovskaja Oblast
S-Pb clinical scientific practical center of specialized kinds of medical care (oncological), Saint-Petersburg, Sankt Petersburg
Clinical Oncology Dispensary of Ministry of Health of Tatarstan, Kazan, Tatarstan
Limited Liability Company "RC Medical", Novosibirsk, Not set
National Cancer Centre; Medical Oncology, Singapore, Not set
National Hospital; Oncotherapy Dept, Bloemfontein, Not set
Cancercare, George, Not set
Wits Clinical Research, Johannesberg, Not set
Cancercare, Port Elizabeth, Not set
Wilgers Oncology Centre, Pretoria, Not set
Hospital Univ Vall d'Hebron; Servicio de Oncologia, Sant Andreu de La Barca, Barcelona
Hospital Provincial de Castellon; Servicio de Oncologia, Castellon de La Plana, Castellon
Complejo Hospitalario Universitario A Coruña (CHUAC); Servicio de Oncologia, A Coruña, LA Coruña
Hospital Universitario Puerta de Hierro; Servicio de Oncologia, Majadahonda, Madrid
Hospital Clínic i Provincial; Servicio de Hematología y Oncología, Barcelona, Not set
Hospital General Universitario Gregorio Marañon; Servicio de Oncologia, Madrid, Not set
Hospital Ramon y Cajal; Servicio de Oncologia, Madrid, Not set
Hospital Universitario Clínico San Carlos; Servicio de Oncologia, Madrid, Not set
Centro Integral Oncologico Clara Campal; Servicio de Oncología, Madrid, Not set
Hospital Clinico Universitario Virgen de la Victoria; Servicio de Oncologia, Malaga, Not set
Hospital Clínico Universitario de Valencia; Servicio de Oncología, Valencia, Not set
Universitätsspital Basel, Basel, Not set
Universitätsspital Zürich Gynäkologische Klinik; Klinik für Gynäkologie, Zürich, Not set
China Medical University Hospital; Surgery, Taichung, Not set
VETERANS GENERAL HOSPITAL; Department of General Surgery, Taipei, Not set
National Taiwan Uni Hospital; General Surgery, Taipei, Not set
Chang Gung Memorial Hosipital at Linkou, Taoyuan City, Not set
Chulalongkorn Hospital; Medical Oncology, Bangkok, Not set
Rajavithi Hospital; Division of Medical Oncology, Bangkok, Not set
Faculty of Med. Siriraj Hosp.; Med.-Div. of Med. Oncology, Bangkok, Not set
Maharaj Nakorn Chiang Mai Hospital; Department of Surgery/Head Neck and Breast Unit; Clinical Trial, Chiang Mai, Not set
Khonkaen Hospital, Khonkaen, Not set
Songklanagarind Hospital; Department of Oncology, Songkhla, Not set
Memorial Ankara Hastanesi, Ankara, Not set
Medipol University Medical Faculty; Oncology Department, Istanbul, Not set
Hacettepe Uni Medical Faculty Hospital; Oncology Dept, Sihhiye/Ankara, Not set
SI Institute of general&urgent surgery n/a Zaytseva V.T NAMSU; Purulent Surgery department, Kharkiv, Kharkiv Governorate
Regional Oncology Center; Department of Mammology, Chernigiv, Not set
Chemotherapy SI Dnipropetrovsk MA of MOHU, Dnipropetrovsk, Not set
ME Kryviy Rih Oncology Dispensary of Dnipropetrovs?k Regional Council; Chemotherapy Department, Kryvyi Rih, Not set
MI Kyiv Regional Council Kyiv Regional Oncological Dispensary; Department of Mammology, Kyiv, Not set
Municipal Institution Odesa Regional Clinical Hospital, Odesa, Not set
RCI Sumy Regional Clinical Oncological Dispensary, Sumy, Not set
BEATSON WEST OF SCOTLAND CANCER CENTRE; Clinical Research Unit ? Level 1, Glasgow, Not set
The Royal Marsden Hospital, Fulham, London, Not set
Nottingham University Hospitals NHS Trust, Nottingham, Not set
Conditions: Triple-Negative Breast Cancer
A Study of Ipatasertib in Combination With Paclitaxel as a Treatment for Participants With PIK3CA/AKT1/PTEN-Altered, Locally Advanced or Metastatic, Triple-Negative Breast Cancer or Hormone Receptor-Positive, HER2-Negative Breast Cancer
Completed
This study will evaluate the efficacy of ipatasertib + paclitaxel versus placebo + paclitaxel in participants with histologically confirmed, locally advanced or metastatic triple-negative breast cancer (TNBC) and in participants with locally advanced or metastatic hormone receptor positive (HR+)/ human epidermal growth factor receptor 2 negative (HER2-) breast adenocarcinoma who are not suitable for endocrine therapy.
This study will evaluate the efficacy of ipatasertib + paclitaxel versus placebo + paclitaxel in participants with histologically confirmed, locally advanced or metastatic triple-negative breast cancer (TNBC) and in participants with locally advanced or metastatic hormone receptor positive (HR+)/ human epidermal growth factor receptor 2 negative (HER2-) breast adenocarcinoma who are not suitable for endocrine therapy. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/15/2024
Locations: UCSD Moores Cancer Center, La Jolla, California +175 locations
UCSD Moores Cancer Center, La Jolla, California
USC Norris Cancer Center, Los Angeles, California
USC Norris Cancer Center; USC Oncology Hematology Newport Beach, Newport Beach, California
Kaiser Permanente - Oakland, Oakland, California
Kaiser Permanente - Roseville, Roseville, California
UC Davis; Comprehensive Cancer Center, Sacramento, California
Kaiser Permanente Sacramento Medical Center, Sacramento, California
Kaiser Permanente - San Francisco (2238 Geary), San Francisco, California
UCSF Comprehensive Cancer Ctr, San Francisco, California
K. Permanente - San Jose, San Jose, California
Kaiser Permanente - San Leandro, San Leandro, California
K. Permanente - Santa Clara, Santa Clara, California
Kaiser Permanente - South San Francisco, South San Francisco, California
Kaiser Permanente - Vallejo, Vallejo, California
K. Permanente - Walnut Creek, Walnut Creek, California
Memorial Regional Hospital, Hollywood, Florida
Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida
UF Health Cancer Center at Orlando Health, Orlando, Florida
Memorial Hospital West, Pembroke Pines, Florida
University of Maryland, Baltimore, Maryland
Mercy Medical Center, Baltimore, Maryland
Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
Memorial Sloan Kettering Cancer Center at Westchester, Harrison, New York
Memorial Sloan Kettering, New York, New York
West Clinic, Germantown, Tennessee
Texas Oncology, P.A., Dallas, Texas
UT Southwestern Medical Center; Simmons Comprehensive Cancer Center, Simmons Pharmacy, Dallas, Texas
Oncology Consultants PA, Houston, Texas
Fundación CENIT para la Investigación en Neurociencias, Buenos Aires, Not set
Hosp Provincial D. Centenarios; Oncology Dept, Rosario, Not set
Chris O'Brien Lifehouse, Camperdown, New South Wales
Calvary Mater Newcastle; Medical Oncology, Waratah, New South Wales
Westmead Hospital; Medical Oncology, Wentworthville, New South Wales
Mater Hospital; Cancer Services, South Brisbane, Queensland
Cabrini Medical Centre; Oncology, Malvern, Victoria
Fiona Stanley Hospital; FSH Cancer Centre Clinical Trials Unit, Bull Creek, Western Australia
Cliniques Universitaires St-Luc, Bruxelles, Not set
GHdC Site Notre Dame, Charleroi, Not set
UZ Leuven Gasthuisberg, Leuven, Not set
Santa Casa de Misericordia de Salvador, Salvador, BA
Hospital Araujo Jorge; Departamento de Ginecologia E Mama, Goiania, GO
Hospital do Câncer de Londrina, Londrina, PR
Instituto Nacional de Cancer - INCa; Oncologia, Rio de Janeiro, RJ
Hospital Sao Lucas - PUCRS, Porto Alegre, RS
Hospital Nossa Senhora da Conceicao, Porto Alegre, RS
Faculdade de Medicina do ABC - FMABC, Santo Andre, SP
Hospital Perola Byington, Sao Paulo, SP
British Columbia Cancer Agency (Bcca) - Vancouver Cancer Centre, Vancouver, British Columbia
Jewish General Hospital, Montreal, Quebec
Sociedad de Investigaciones Medicas Ltda (SIM), Temuco, Not set
Clinica CIMCA, San José, Not set
ICIMED Instituto de Investigación en Ciencias Médicas, San José, Not set
Masaryk?v onkologický ústav; Klinika komplexní onkologické pé?e, Brno, Not set
Fakultni nemocnice Olomouc; Onkologicka klinika, Olomouc, Not set
CHU Besançon - Hôpital Jean Minjoz, Besançon Cedex, Not set
Polyclinique Bordeaux Nord Aquitaine, Bordeaux, Not set
Centre Georges Francois Leclerc; Oncologie 3, Dijon, Not set
ICM; Medecine B3, Montpellier cedex 5, Not set
Centre Catherine De Sienne, Nantes, Not set
APHP - Hospital Saint Louis, Paris, Not set
Institut Jean Godinot; Oncologie Medicale, Reims CEDEX, Not set
Onkologische Schwerpunktpraxis Kurfürstendamm, Berlin, Not set
Praxis für Interdisziplinäre Onkologie und Hämatologie GbR, Freiburg, Not set
Universitätsklinikum Hamburg-Eppendorf; Frauenklinik, Hamburg, Not set
Universitätsklinikum des Saarlandes; Klinik f. Frauenheilkunden und Geburtshilfe, Homburg/Saar, Not set
Praxis Dr.med. Katja Ziegler-Löhr, Köln, Not set
Dres. Andreas Köhler und Roswitha Fuchs, Langen, Not set
Mühlenkreiskliniken; Johannes Wesling Klinikum Minden; Klinik für Frauenheilkunde und Geburtshilfe, Minden, Not set
Oncologianova GmbH - Gesellschaft für Innovationen in der Onkologie, Recklinghausen, Not set
Universitätsfrauen- und Poliklinik am Klinikum Suedstadt, Rostock, Not set
Universitätsklinikum Würzburg; Frauenklinik, Würzburg, Not set
Anticancer Hospital Ag Savas; 1St Dept of Internal Medicine, Athens, Not set
Agioi Anargyroi; 3Rd Dept. of Medical Oncology, Athens, Not set
Euromedical General Clinic of Thessaloniki; Oncology Department, Thessaloniki, Not set
Orszagos Onkologial Intezet; Onkologiai Osztaly X, Budapest, Not set
Borsod-Abauj-Zemplen Megyei Korhaz Es Egyetemi Oktato Korhaz; Onkologiai Osztaly, Miskolc, Not set
Szegedi Tudomanyegyetem, AOK, Szent-Gyorgyi Albert Klinikai Kozpont, Onkoterapias Klinika, Szeged, Not set
Hetenyi Geza County Hospital; Onkologiai Kozpont, Szolnok, Not set
Zala County Hospital ICU, Zalaegerszeg, Not set
Indraprastha Apollo Hospitals, New Delhi, Delhi
Rajiv Gandhi Cancer Inst.&Research Center; Medical Oncology, New Delhi, Delhi
Istituto Nazionale Tumori Irccs Fondazione g. PASCALE;U.O.C. Oncologia Medica Senologica, Napoli, Campania
Azienda Ospedaliero-Universitaria S.Orsola-Malpighi; Unità Operativa Oncologia Medica, Bologna, Emilia-Romagna
Irccs Centro Di Riferimento Oncologico (CRO); Dipartimento Di Oncologia Medica, Aviano, Friuli-Venezia Giulia
Ospedale Santa Maria Annunziata; Oncologia, Bagno a Ripoli, Toscana
IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II, Padova, Veneto
Aichi Cancer Center Hospital, Aichi, Not set
National Cancer Center Hospital East, Chiba, Not set
National Hospital Organization Kyushu Cancer Center;Breast Oncology, Fukuoka, Not set
Fukushima Medical University Hospital, Fukushima, Not set
Hyogo Medical University Hospital, Hyogo, Not set
St. Marianna University Hospital, Kanagawa, Not set
Kanagawa Cancer Center, Kanagawa, Not set
Tokai University Hospital, Kanagawa, Not set
Kumamoto Shinto General Hospital, Kumamoto, Not set
Niigata Cancer Center Hospital, Niigata, Not set
Okayama University Hospital, Okayama, Not set
National Hospital Organization Osaka National Hospital, Osaka, Not set
Kinki University Hospital, Faculty of Medicine; Surgery, Osaka, Not set
Saitama Cancer Center, Breast Oncology, Saitama, Not set
Shizuoka Cancer Center, Shizuoka, Not set
National Cancer Center Hospital, Tokyo, Not set
St. Luke's International Hospital, Tokyo, Not set
The Cancer Institute Hospital of JFCR, Tokyo, Not set
Showa University Hospital; Breast Surgery, Tokyo, Not set
National Cancer Center, Goyang-si, Not set
Inha University Hospital, Incheon, Not set
Seoul National University Bundang Hospital, Seongnam-si, Not set
Seoul National University Hospital, Seoul, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Centro Medico Dalinde, Cdmx, Mexico CITY (federal District)
Centro Médico Zambrano Hellion, Monterrey, Nuevo LEON
Merida | Investigacion Clinica, Mérida, Yucatan
CENEIT Oncologicos; DENTRO DE CONDOMINIO SAN FRANCISCO, Mexico City, Not set
Clinical Hospital; Oncology Department, Bitola, Not set
PHI University Clinic of Radiotherapy and Oncology; Breast malignancy, Skopje, Not set
PHI University Clinic of Radiotherapy and Oncology; Malignant diseases of thorax, Skopje, Not set
Centro Medico Monte Carmelo, Arequipa, Not set
Hospital Daniel Alcides Carrion, Callao, Not set
Clínica San Gabriel; Unidad de Investigación Oncológica de la Clínica San Gabriel, Lima, Not set
Hospital Nacional Cayetano Heredia; Ocología; Servicio de Hematología Oncología Médica, Lima, Not set
Oncosalud Sac; Oncología, Lima, Not set
Instituto Nacional de Enfermedades Neoplasicas, Lima, Not set
Clinica Ricardo Palma, San Isidro, Not set
Instituto Regional de Enfermedades Neoplasicas - IREN Norte, Trujillo, Not set
Instyt. Centrum Zdrowia Matki Polki; Klinika Chirurgii Onk. Chorób Piersi z Podod. Onko Klinicznej, ?ód?, Not set
Narodowy Inst.Onkol.im.Sklodowskiej-Curie Panstw.Inst.Bad Gliwice; III Klin. Radioter. i Chemioter., Gliwice, Not set
Narodowy Instytut Onkologii im. M.Sklodowskiej-Curie; Klinika Nowotworow Piersi i Chirurgii Rekonstr, Warszawa, Not set
Arkhangelsk Regional Clinical Oncology Dispensary, Arkhangelsk, Arhangelsk
Moscow City Oncology Hospital #62, Moscovskaya Oblast, Moskovskaja Oblast
Federal State Institution, Moscow Research Oncology Institute n.a. P.A. Hertzen; Oncourology, Moscow, Moskovskaja Oblast
Blokhin Cancer Research Center; Combined Treatment, Moskva, Moskovskaja Oblast
FSI Rostov research oncological institute of MoH and SD of RF; PAD, Rostov-on-Don, Rostov
S-Pb clinical scientific practical center of specialized kinds of medical care (oncological), Saint-Petersburg, Sankt Petersburg
Clinical Oncology Dispensary of Ministry of Health of Tatarstan, Kazan, Tatarstan
Ivanovo Regional Oncology Dispensary, Ivanovo, Not set
SBIH Kaluga Region Clinical Oncology Dispensary, Kaluga, Not set
National University Hospital; National University Cancer Institute, Singapore (NCIS), Singapore, Not set
National Cancer Centre; Medical Oncology, Singapore, Not set
Institute of Oncology Ljubljana, Ljubljana, Not set
Medical Oncology Centre of Rosebank; Oncology, Johannesburg, Not set
Hospital Provincial de Castellon; Servicio de Oncologia, Castellon de La Plana, Castellon
Hospital Universitario Reina Sofia; Servicio de Oncologia, Córdoba, Cordoba
Complejo Hospitalario Universitario de Santiago (CHUS) ; Servicio de Oncologia, Santiago de Compostela, LA Coruña
Hospital Universitario Puerta de Hierro; Servicio de Oncologia, Majadahonda, Madrid
Hospital del Mar; Servicio de Oncologia, Barcelona, Not set
Vall d?Hebron Institute of Oncology (VHIO), Barcelona, Barcelona, Not set
Hospital Clinic Barcelona; Servicio de oncologia, Barcelona, Not set
Hospital de Donostia; Servicio de Oncologia, Guipuzcoa, Not set
Hospital Ramon y Cajal; Servicio de Oncologia, Madrid, Not set
HOSPITAL DE MADRID NORTE SANCHINARRO- CENTRO INTEGRAL ONCOLOGICO CLARA CAMPAL; Servicio de Oncologia, Madrid, Not set
Hospital Universitario Virgen del Rocio; Servicio de Oncologia, Sevilla, Not set
Hospital Clinico Universitario; Oncologia, Valencia, Not set
Chi Mei Medical Center Liou Ying Campus, Liuying Township, Not set
Koo Foundation Sun Yat-Sen Cancer Center; Hemato-Oncology, Taipei City, Not set
VETERANS GENERAL HOSPITAL; Department of General Surgery, Taipei, Not set
National Taiwan Uni Hospital; General Surgery, Taipei, Not set
Ankara Bilkent City Hospital, Ankara, Not set
Dicle Uni Medical Faculty; Internal Medicine, Diyarbakir, Not set
Medipol University Medical Faculty; Oncology Department, Istanbul, Not set
Prof. Dr. Cemil Tascioglu City Hospital; Med Onc, Istanbul, Not set
Katip Celebi University Ataturk Training and Research Hospital; Oncology, Izmir, Not set
Sakarya University Medical School; Medical Oncology, Sakarya, Not set
Chemotherapy SI Dnipropetrovsk MA of MOHU, Dnipropetrovsk, Not set
Kyiv City Clinical Oncological Center, Day Hospital Department for Oncological patients, Kiev, Not set
National Cancer Institute MOH of Ukraine, Kiev, Not set
Lviv State Oncological Regional Treatment and Diagnostic Center, Lviv, Not set
Velindre Cancer Centre, Cardiff, Not set
University Hospital coventry; Oncology Department, Coventry, Not set
The Beatson West of Scotland Cancer Centre; Cancer Clinical Trials Unit, Glasgow, Not set
Royal Marsden Hospital - London, London, Not set
Derriford Hospital, Plymouth, Not set
Royal Stoke University Hospital, Stoke-on-Trent, Not set
Royal Marsden Hospital; Dept of Medical Oncology, Sutton, Not set
Conditions: Breast Cancer
Basket Study of Neratinib in Participants With Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations
Terminated
This is an open-label, multicenter, multinational, Phase 2 basket study exploring the efficacy and safety of neratinib as monotherapy or in combination with other therapies in participants with HER (EGFR, HER2) mutation-positive solid tumors.
This is an open-label, multicenter, multinational, Phase 2 basket study exploring the efficacy and safety of neratinib as monotherapy or in combination with other therapies in participants with HER (EGFR, HER2) mutation-positive solid tumors. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/12/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +59 locations
University of Alabama at Birmingham, Birmingham, Alabama
Mayo Clinic Arizona, Phoenix, Arizona
City of Hope, Duarte, California
University of California, San Diego, La Jolla, California
University of Southern California, Los Angeles, California
University of California, Los Angeles, Los Angeles, California
Stanford Cancer Center, Palo Alto, California
UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California
Kaiser Permanente NoCal (STRATA), Vallejo, California
Mayo Clinic Florida, Jacksonville, Florida
University of Miami, Miami, Florida
Winship Cancer Institute, Emory University, Atlanta, Georgia
Northwestern University, Chicago, Illinois
Ochsner Clinic Foundation, New Orleans, Louisiana
Dana Farber Cancer Institute, Boston, Massachusetts
University of Michigan, Ann Arbor, Michigan
Mayo Clinic, Rochester, Minnesota
Metro Minnesota Community Oncology Research Consortium, Saint Louis Park, Minnesota
Washington University, Saint Louis, Missouri
Roswell Park Comprehensive Cancer Center, Buffalo, New York
Memorial Sloan-Kettering Cancer Center, New York, New York
UPMC Magee-Woman's Hospital, Women's Cancer Center, Pittsburgh, Pennsylvania
Saint Francis Cancer Center-Bon Secours, Greenville, South Carolina
The West Clinic, Germantown, Tennessee
Vanderbilt-Ingram Cancer Center, Nashville, Tennessee
UT Southwestern Medical Center, Dallas, Texas
MD Anderson Cancer Center, Houston, Texas
Seattle Cancer Care Alliance, Seattle, Washington
Gundersen Center for Cancer and Blood Disorders, La Crosse, Wisconsin
University of Wisconsin Carbone Cancer Center, Madison, Wisconsin
Peter MacCallum Cancer Centre, East Melbourne, Victoria
UZ Leuven, Leuven, Not set
British Columbia Cancer Center, Vancouver, British Columbia
University Hospital, Rigshospitalet, Kopenhagen, Not set
Institut Curie - Hopital Rene Huguenin, Saint-Cloud, Ile De France
Institut Gustave Roussy, Villejuif, Paris
Institut Bergonié, Bordeaux, Not set
Centre Leon Berard, Lyon, Not set
St. Vincent's University Hospital, Dublin, Leinster
Hadassah Medical Center, Jerusalem, Not set
Davidoff Cancer Center, Rabin Medical Center, Petah Tikva, Not set
Sheba Medical Center, Ramat Gan, Not set
Kaplan Medical Center, Rehovot, Not set
Sourasky Medical Center, Tel Aviv, Not set
Azienda Socio Sanitaria Territoriale di Cremona, Cremona, Not set
Istituto Europeo di Oncologia (IEO) I.R.C.C.S., Milano, Not set
Fondazione Policlinico Universitario Gemelli I.R.C.C.S., Roma, Not set
AOU Citta della Salute e della Scienza di Torino, Torino, Not set
Yonsei University Health System, Serverance Hospital, Seodaemun-Gu, Seoul
Institute for Oncology and Radiology of Serbia, Belgrade, Not set
Hospital Universitario Quiron Dexeus, Barcelona, Not set
Hospital Universitario Vall d'Hebron, Barcelona, Not set
Hospital Universitari Clinic Barcelona, Barcelona, Not set
Hospital Clinico Universitario San Carlos, Madrid, Not set
Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set
Hospital Universitario Madrid Sanchinarro (START Madrid), Madrid, Not set
Hospital Universitario Quiron Madrid, Madrid, Not set
Instituto Valenciano de Oncologia, Valencia, Not set
Hospital Clinico Universitario de Valencia, Valencia, Not set
Royal Free Hospital, London, Not set
Conditions: Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations
PRIMUS 001: A Study Looking at Two Different Chemotherapy Regimens in Patients With Metastatic Pancreatic Cancer
Recruiting
This study is comparing two combinations of chemotherapy treatments in patients with metastatic pancreatic cancer. Half the participants will receive FOLFOX-A and the other half will receive AG. Treatment will continue until progression or patient/clinican decision or intolerable toxicity.
This study is comparing two combinations of chemotherapy treatments in patients with metastatic pancreatic cancer. Half the participants will receive FOLFOX-A and the other half will receive AG. Treatment will continue until progression or patient/clinican decision or intolerable toxicity. Read Less
Gender:
ALL
Ages:
16 years and above
Trial Updated:
02/07/2024
Locations: Aberdeen Royal Infirmary, Aberdeen, Not set +29 locations
Aberdeen Royal Infirmary, Aberdeen, Not set
Northern Ireland Cancer Centre, Belfast, Not set
Queen Elizabeth Hospital, Birmingham, Not set
Royal Bournemouth Hospital, Bournemouth, Not set
Bristol Oncology Centre, Bristol, Not set
Addenbrooke's Hospital, Cambridge, Not set
Castle Hill Hospital, Cottingham, Not set
Ninewells Hospital, Dundee, Not set
Western General, Edinburgh, Not set
Beatson West of Scotland Cancer Centre, Glasgow, Not set
Huddersfield Royal Infirmary, Huddersfield, Not set
Raigmore Hospital, Inverness, Not set
St James's University Hospital, Leeds, Not set
The Clatterbridge Cancer Centre, Liverpool, Not set
Guy's Hospital, London, Not set
Imperial College Healthcare Trust, London, Not set
Royal Free London Hospital, London, Not set
Royal Marsden Hospital, London, Not set
St Bart's Hospital, London, Not set
St George's Hospital, London, Not set
University College London Hospital, London, Not set
The Christie, Manchester, Manchester, Not set
Milton Keynes General Hospital, Milton Keynes, Not set
Freeman Hospital, Newcastle, Not set
Nottingham University Hospital, Nottingham, Not set
Churchill Hospital, Oxford, Not set
Poole Hospital, Poole, Not set
Weston Park, Sheffield, Not set
University of Southampton Hospital, Southampton, Not set
Singleton Hospital, Swansea, Not set
Conditions: Neoplasms Pancreatic
European Study of POBA Versus Cotavance(R) Paclitaxel Coated Balloon for the Treatment of Infrapopliteal Lesions in Critical Limb Ischemia (EURO CANAL)
Terminated
To evaluate the procedural safety and to identify and characterize therapeutic and functional endpoint assessments in subjects with documented critical limb ischemia who received treatment with the Cotavance Paclitaxel-Coated Balloon vs. those who received POBA only.
To evaluate the procedural safety and to identify and characterize therapeutic and functional endpoint assessments in subjects with documented critical limb ischemia who received treatment with the Cotavance Paclitaxel-Coated Balloon vs. those who received POBA only. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: Medical University, Graz, Not set +5 locations
Medical University, Graz, Not set
AZ St.-Blasius Hospital, Dendermonde, Not set
University Hospital, Gent, Not set
University Hospital, Bern, Not set
University Hospital, Zurich, Not set
St. George's Hospital, London, Not set
Conditions: PAD, Infrapopliteal Lesions
Adjuvant Palbociclib in Elderly Patients With Breast Cancer
Active Not Recruiting
Phase II study to assess the efficacy of the combination of at least 5 year endocrine therapy and 2 year-palbociclib as adjuvant systemic treatment instead of adjuvant chemotherapy followed by endocrine therapy in older patients with stage II-III ER+/HER2- early breast cancer.
Phase II study to assess the efficacy of the combination of at least 5 year endocrine therapy and 2 year-palbociclib as adjuvant systemic treatment instead of adjuvant chemotherapy followed by endocrine therapy in older patients with stage II-III ER+/HER2- early breast cancer. Read Less
Gender:
ALL
Ages:
70 years and above
Trial Updated:
01/23/2024
Locations: Cliniques Universitaires Saint-Luc, Brussels, Not set +72 locations
Cliniques Universitaires Saint-Luc, Brussels, Not set
Institut Jules Bordet-Hopital Universitaire ULB, Brussels, Not set
AZ Maria Middelares, Gent, Not set
U.Z. Leuven - Campus Gasthuisberg, Leuven, Not set
Heilig Hartziekenhuis Lier, Lier, Not set
C.H.U. Sart-Tilman, Liège, Not set
AZ Nikolaas - Campus SL, Sint-Niklaas, Not set
AZ Turnhout - Campus Sint Elisabeth, Turnhout, Not set
Institut Bergonie, Bordeaux, Not set
CHU-Lyon - Hopital Femme Mere Enfant, Brou, Not set
Centre Francois Baclesse (CLCC), Caen, Not set
Centre Jean Perrin, Clermont Ferrand, Not set
Centre Hospitalier Departemental Vendée, La Roche-sur-Yon, Not set
Centre Oscar Lambret, Lille, Not set
CHU de Limoges - Hopital Dupuytren, Limoges, Not set
Centre Leon Berard, Lyon, Not set
CHU de Lyon - Hopital De La Croix Rousse, Lyon, Not set
Hospital prive du Confluent - Centre Catherine de Sienne, Nantes, Not set
CHU de Lyon - Hopital Lyon Sud, Pierre-Bénite, Not set
Centre Henri Becquerel, Rouen, Not set
Institut Curie - l' Hopital de St Cloud, Saint-Cloud, Not set
Institut Claudius Regaud, Toulouse, Not set
Kliniken Essen-Mitte, Essen, Not set
Klinikum Frankfurt Hoechst GmbH, Frankfurt Am Main, Not set
Universitaetskliniken Des Saarlandes, Homburg / Saar, Not set
ORTENAU KLINIKUM Offenburg-Gengenbach - Klinikum Offenburg Ebertplatz, Offenburg, Not set
Onkologie Haematologie Gemeinschaftspraxis - Studienzentrum Onkologie Ravensburg, Ravensburg, Not set
Marienkrankenhaus Schwerte, Schwerte, Not set
Marienhospital Stuttgart, Stuttgart, Not set
Kreiskrankenhaus Torgau, Torgau, Not set
Schwarzwald-Baar Klinikum, Villingen-Schwenningen, Not set
Marienhospital Witten, Witten, Not set
Ospedale Degli Infermi, Biella, Not set
Ospedale Generale Regionale, Bolzano, Not set
Ospedale B. Ramazzini, Carpi, Not set
Riccione Hospital Unit - Ospedale Cervesi di Cattolica, Cattolica, Not set
Faenza Hospital Unit - Ospedale degli Infermi, Faenza, Not set
IRCCS Azienda Ospedaliera Universitaria San Martino "IST" - IRCCS - AUO San Martino - IST, Genova, Not set
Ospedale Civile Guastalla, Guastalla, Not set
AULSS 9 - Azienda Unita Locale Socio-Sanitaria N. 9-Mater Salutis Hospital, Legnago, Not set
Lugo Hospital Unit -Ospedale Umberto I, Lugo, Not set
Azienda Ospedaliero - Universitaria Policlinico di Modena, Modena, Not set
Ospedale San Gerardo, Monza, Not set
Rimini Hospital Unit - Ospedale Sacra Famiglia, Novafeltria, Not set
Casa di Cura La Maddalena S.P.A., Palermo, Not set
Ospedale Santa Maria delle Croci, Ravenna, Not set
AUSL Romagna - Rimini Hospital Unit - Infermi Hospital, Rimini, Not set
Azienda Ospedaliera Citta della Salute e della Scienza di Torino - Azienda Ospedaliera Città della Salute e della Scienza di Torino - Ospedale Sant'Anna, Torino, Not set
Azienda Ospedaliero Universitaria - Ospedali Riuniti, Torrette, Not set
King Hussein Cancer Center, Amman, Not set
Medical University Of Gdansk, Gdansk, Not set
Maria Sklodowska-Curie Memorial Cancer Centre - Maria Sklodowska - Curie's National Institute of Oncology - National Research Institute, Warsaw, Not set
Champalimaud Clinical Center, Lisboa, Not set
Centro Hospitalar do Porto-- Hospital de Santo Antonio, Porto, Not set
Instituto Portugues De Oncologia - Instituto Portugues de Oncologia do Porto, Porto, Not set
Hospital Clinic Universitari de Barcelona, Barcelona, Not set
Hospital Universitari Vall d'Hebron, Barcelona, Not set
Institut Catala d'Oncologia - ICO Badalona - Hospital De Mataro, Barcelona, Not set
Hospital Universitari Arnau De Vilanova, Lleida, Not set
Centro Oncológico MD Anderson, Madrid, Not set
Hospital Severo Ochoa, Madrid, Not set
Hospital Universitario 12 De Octubre, Madrid, Not set
Hospital Universitario QuironSalud, Madrid, Not set
Hospitales HM Sanchinarro-CIOCC, Madrid, Not set
Hospital Sant Joan de Reus, Reus, Not set
Hospital Universitario Virgen de Valme, Sevilla, Not set
Virgen del Rocio University Hospital, Sevilla, Not set
Fundacion Instituto Valenciano De Oncologia, Valencia, Not set
Hospital Clinico Universitario De Valencia, Valencia, Not set
Blackpool Teaching Hospitals NHS Foundation Trust - Blackpool Victoria Hospital-NHS Fundation Trust, Blackpool, Not set
NHS Lothian - Western General Hospital, Edinburgh, Not set
Barts Health NHS Trust - St. Bartholomew'S Hospital, London, Not set
NHS Borders - Borders General Hospital Melrose By-pass, Melrose, Not set
Conditions: Breast Cancer Stage II, Breast Cancer Stage III
Olaparib +/- Cediranib or Chemotherapy in Patients With Platinum-resistant Ovarian Cancer
Completed
The trial will compare the drugs olaparib and cediranib with standard chemotherapy in platinum resistant ovarian cancer. Patients will be randomised to one of three treatment groups: olaparib only, olaparib and cediranib and the control group paclitaxel. The aim is to compare efficacy of the 3 treatments and also how well each treatment is tolerated including the participants quality of life.
The trial will compare the drugs olaparib and cediranib with standard chemotherapy in platinum resistant ovarian cancer. Patients will be randomised to one of three treatment groups: olaparib only, olaparib and cediranib and the control group paclitaxel. The aim is to compare efficacy of the 3 treatments and also how well each treatment is tolerated including the participants quality of life. Read Less
Gender:
FEMALE
Ages:
16 years and above
Trial Updated:
01/22/2024
Locations: Belfast City Hospital, Belfast, County Antrim +13 locations
Belfast City Hospital, Belfast, County Antrim
Mount Vernon Cancer Centre, Northwood, Middlesex
City Hospital Nottingham, Nottingham, Nottinghamshire
Royal Surrey County Hospital, Guildford, Surrey
Royal United Hospital, Bath, Not set
Velindre, Cardiff, Not set
Beatson West of Scotland Cancer Centre, Glasgow, Not set
Clatterbridge Cancer Centre, Liverpool, Not set
St Bartholomew's, London, Not set
Hammersmith Hospital, London, Not set
Royal Marsden Chelsea & Sutton, London, Not set
University College London, London, Not set
The Christie, Manchester, Not set
Churchill Hospital, Oxford, Not set
Conditions: Ovarian Cancer
Study to Evaluate Ibrutinib Combination Therapy in Patients With Selected Gastrointestinal and Genitourinary Tumors
Completed
The purpose of this study is to evaluate the safety, tolerability, and efficacy of single agent ibrutinib or the combination treatments of ibrutinib with everolimus, paclitaxel, docetaxel, pembrolizumab or cetuximab in selected advance gastrointestinal and genitourinary tumors.
The purpose of this study is to evaluate the safety, tolerability, and efficacy of single agent ibrutinib or the combination treatments of ibrutinib with everolimus, paclitaxel, docetaxel, pembrolizumab or cetuximab in selected advance gastrointestinal and genitourinary tumors. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/14/2023
Locations: Clearview Cancer Institute /ID# 1128-0965, Huntsville, Alabama +64 locations
Clearview Cancer Institute /ID# 1128-0965, Huntsville, Alabama
Banner MD Anderson Cancer Center /ID# 1128-0802, Gilbert, Arizona
University of Arizona Cancer Center - Tucson /ID# 1128-1546, Tucson, Arizona
Alta Bates Comprehensive Cancer Center /ID# 1128-0135, Berkeley, California
St Marys Medical Center /ID# 1128-0969, Daly City, California
Duplicate_University of California San Diego/ Moores Cancer Center /ID# 1128-0241, La Jolla, California
VA Long Beach Healthcare System /ID# 1128-0480, Long Beach, California
USC Norris Cancer Center /ID# 1128-0209, Los Angeles, California
UC Irvine Medical Center - Chao Family Comprehensive Cancer Center /ID# 1128-0008, Orange, California
Gregory Smith, MD (Private Practice) /ID# 1128-0419, Saint Helena, California
Salinas Valley Memorial Hosp /ID# 1128-0482, Salinas, California
Premiere Oncology, A Medical Corporation /ID# 1128-1085, Santa Monica, California
St. Joseph Health /ID# 1128-1462, Santa Rosa, California
Whittingham Cancer Center at Norwalk Hospital /ID# 1128-0411, Norwalk, Connecticut
Georgetown University Hospital /ID# 1128-0824, Washington, District of Columbia
Duplicate_Cancer Specialist of North Florida (CSNF) ( R ) /ID# 1128-1093, Jacksonville, Florida
IACT Health-Columbus /ID# 1128-1389, Columbus, Georgia
Northshore Kellogg Cancer Center /ID# 1128-0484, Evanston, Illinois
Franciscan Health Indianapolis /ID# 1128-1125, Indianapolis, Indiana
Horizon Oncology Research Center /ID# 1128-0337, Lafayette, Indiana
University of Iowa Hospitals and Clinics /ID# 1128-0766, Iowa City, Iowa
The University of Kansas Cancer Center /ID# 1128-0706, Fairway, Kansas
East Jefferson General Hospital /ID# 1128-1084, Metairie, Louisiana
Duplicate_Tufts Medical Center /ID# 1128-0016, Boston, Massachusetts
Barbara Ann Karmanos Cancer In /ID# 1128-0130, Detroit, Michigan
Henry Ford Hospital /ID# 1128-0195, Detroit, Michigan
Central Care Cancer Center /ID# 1128-1596, Bolivar, Missouri
Capital Region Medical Center /ID# 1128-1412, Jefferson City, Missouri
Nebraska Methodist Hospital /ID# 1128-0229, Omaha, Nebraska
New Jersey Center for Cancer Research /ID# 1128-0493, Brick, New Jersey
Duplicate_New Mexico Cancer Care Alliance /ID# 1128-0938, Albuquerque, New Mexico
San Juan Oncology Associates /ID# 1128-1020, Farmington, New Mexico
Memorial Sloan Kettering Cancer Center-Koch Center /ID# 1128-0091, New York, New York
Wake Forest Univ HS /ID# 1128-0975, Winston-Salem, North Carolina
Oregon Health & Science University /ID# 1128-0251, Portland, Oregon
Penn State Hershey Medical Ctr /ID# 1128-0220, Hershey, Pennsylvania
Abramson Cancer Center of the Univ. of Pennsylvania /ID# 1128-0402, Philadelphia, Pennsylvania
Vanderbilt Infectious Disease Clinic /ID# 1128-0024, Nashville, Tennessee
The University of Texas Medical Branch (UTMB) - Cancer Center - Galves /ID# 1128-0974, Galveston, Texas
Duplicate_Scott & White Mem Hosp & Clin /ID# 1128-0046, Temple, Texas
Duplicate_Virginia Cancer Specialists - Fairfax Office /ID# 1128-0972, Fairfax, Virginia
Virginia Mason Medical Center /ID# 1128-0005, Seattle, Washington
University of Washington /ID# 1128-1382, Seattle, Washington
Confluence Health /ID# 1128-0894, Wenatchee, Washington
Seoul National University Bundang Hospital /ID# 1128-0982, Seongnam, Gyeonggido
Yonsei University Health System Severance Hospital /ID# 1128-0927, Seoul, Seoul Teugbyeolsi
Chonnam National University Hwasun Hospital /ID# 1128-0916, Jeonnam, Not set
Seoul National University Hospital /ID# 1128-0926, Seoul, Not set
Asan Medical Center /ID# 1128-0963, Seoul, Not set
Samsung Medical Center /ID# 1128-0925, Seoul, Not set
The Catholic University of Korea, Seoul St. Mary's Hospital /ID# 1128-0928, Seoul, Not set
Korea University Guro Hospital /ID# 1128-0924, Seoul, Not set
Instituto Catalan de Oncologia (ICO) Badalona /ID# 1128-0984, Badalona, Barcelona
Hospital Unversitario Marques de Valdecilla /ID# 1128-0973, Santander, Cantabria
Hospital Universitario Vall d'Hebron /ID# 1128-0534, Barcelona, Not set
Hospital Clinic de Barcelona /ID# 1128-0533, Barcelona, Not set
Hospital Universitario Ramon y Cajal /ID# 1128-0874, Madrid, Not set
Hospital Universitario 12 de Octubre /ID# 1128-0864, Madrid, Not set
Hospital Universitario La Paz /ID# 1128-0921, Madrid, Not set
Hospital Universitario Virgen del Rocio /ID# 1128-0863, Sevilla, Not set
Sarah Cannon Research Institute /ID# 1128-1079, London, England
Duplicate_Beatson west of scotland cancer center /ID# 1128-0652, Glasgow, Scotland
The Royal Marsden NHS Foundation Trust /ID# 1128-0543, London, Not set
The Christie Hospital /ID# 1128-0030, Manchester, Not set
Duplicate_Oxford University Hospitals NHS Trust /ID# 1128-0814, Oxford, Not set
Conditions: Metastatic Renal Cell Carcinoma, Advanced Urothelial Carcinoma, Advanced Gastric Adenocarcinoma, Metastatic Colorectal Adenocarcinoma
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