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Paclitaxel Treatment Options in United Kingdom
A collection of 293 research studies where Paclitaxel is the interventional treatment. These studies are located in the United Kingdom . Paclitaxel is used for conditions such as Breast Cancer, Ovarian Cancer and Non-Small Cell Lung Cancer.
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A Study to Compare the Combination of BMS-986504 With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
Not Yet Recruiting
The purpose of this study is to compare the clinical benefit of the combination of BMS-986504 (a selective MTA-cooperative inhibitor of PRMT5) plus pembrolizumab and chemotherapy versus placebo plus pembrolizumab and chemotherapy in first-line metastatic non-small cell lung cancer participants with homozygous MTAP deletion
The purpose of this study is to compare the clinical benefit of the combination of BMS-986504 (a selective MTA-cooperative inhibitor of PRMT5) plus pembrolizumab and chemotherapy versus placebo plus pembrolizumab and chemotherapy in first-line metastatic non-small cell lung cancer participants with homozygous MTAP deletion Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Local Institution - 0119, Anchorage, Alaska +222 locations
Local Institution - 0119, Anchorage, Alaska
Local Institution - 0388, Phoenix, Arizona
Local Institution - 0120, Tucson, Arizona
Local Institution - 0135, Springdale, Arkansas
Local Institution - 0152, Fort Lauderdale, Florida
Local Institution - 0389, Jacksonville, Florida
Local Institution - 0124, Boise, Idaho
Local Institution - 0333, Lexington, Kentucky
Local Institution - 0125, Lexington, Kentucky
Local Institution - 0127, Scarborough, Maine
Local Institution - 0158, Boston, Massachusetts
Local Institution - 0420, Traverse City, Michigan
Local Institution - 0182, Rochester, Minnesota
Local Institution - 0160, Omaha, Nebraska
Local Institution - 0179, Hawthorne, New York
Local Institution - 0128, Rochester, New York
Local Institution - 0163, Cleveland, Ohio
Local Institution - 0129, Columbus, Ohio
Local Institution - 0164, Portland, Oregon
Local Institution - 0348, Portland, Oregon
Local Institution - 0433, Dallas, Texas
Local Institution - 0374, El Paso, Texas
Local Institution - 0132, Houston, Texas
Local Institution - 0377, The Woodlands, Texas
Local Institution - 0354, Salt Lake City, Utah
Local Institution - 0131, Fairfax, Virginia
Local Institution - 0186, Richmond, Virginia
Local Institution - 0145, Seattle, Washington
Local Institution - 0432, Liverpool, New South Wales
Local Institution - 0382, Birtinya, Queensland
Local Institution - 0381, Elizabeth Vale, South Australia
Local Institution - 0367, Ballarat, Victoria
Local Institution - 0207, Wien, Not set
Local Institution - 0227, Edegem, Antwerpen
Local Institution - 0226, Hasselt, Limburg
Local Institution - 0225, Yvoir, Namur
Local Institution - 0277, Roeselare, West-Vlaanderen
Local Institution - 0342, Brussels, Not set
Local Institution - 0340, Liège, Not set
Local Institution - 0088, Vitória, Espírito Santo
Local Institution - 0079, Natal, Rio Grande Do Norte
Local Institution - 0346, Porto Alegre, Rio Grande Do Sul
Local Institution - 0085, Blumenau, Santa Catarina
Local Institution - 0081, Barretos, São Paulo
Local Institution - 0076, Bauru, São Paulo
Local Institution - 0094, Campinas, São Paulo
Local Institution - 0095, Sao Paulo, São Paulo
Local Institution - 0355, São Caetano do Sul, São Paulo
Local Institution - 0351, São José do Rio Preto, São Paulo
Local Institution - 0091, Rio de Janeiro, Not set
Local Institution - 0078, São Paulo, Not set
Local Institution - 0315, Panagyurishte, Pazardzhik
Local Institution - 0309, Haskovo, Not set
Local Institution - 0308, Ruse, Not set
Local Institution - 0307, Stara Zagora, Not set
Local Institution - 0072, Hefei, Anhui
Local Institution - 0074, Beijing, Beijing
Local Institution - 0049, Beijing, Beijing
Local Institution - 0286, Beijing, Beijing
Local Institution - 0046, Fuzhou, Fujian
Local Institution - 0100, Xiamen, Fujian
Local Institution - 0099, Guangzhou, Guangdong
Local Institution - 0061, Guangzhou, Guangdong
Local Institution - 0281, Shenzhen, Guangdong
Local Institution - 0067, Nanning, Guangxi
Local Institution - 0353, Shijiazhuang, Hebei
Local Institution - 0106, Harbin, Heilongjiang
Local Institution - 0107, Zhengzhou, Henan
Local Institution - 0048, Wuhan, Hubei
Local Institution - 0059, Wuhan, Hubei
Local Institution - 0387, Changsha, Hunan
Local Institution - 0050, Changsha, Hunan
Local Institution - 0352, Nanjing, Jiangsu
Local Institution - 0279, Nanjing, Jiangsu
Local Institution - 0110, Nanchang, Jiangxi
Local Institution - 0284, Shenyang, Liaoning
Local Institution - 0104, Shenyang, Liaoning
Local Institution - 0103, Shenyang, Liaoning
Local Institution - 0060, Xi'an, Shaanxi
Local Institution - 0051, Jinan, Shandong
Local Institution - 0066, Linyi, Shandong
Local Institution - 0278, Shanghai, Shanghai
Local Institution - 0343, Shanghai, Shanghai
Local Institution - 0283, Taiyuan, Shanxi
Local Institution - 0109, Cheng Du, Sichuan
Local Institution - 0102, Chengdu, Sichuan
Local Institution - 0280, Hangzhou, Zhejiang
Local Institution - 0069, Hangzhou, Zhejiang
Local Institution - 0054, Hangzhou, Zhejiang
Local Institution - 0386, Nanjing, Not set
Local Institution - 0047, Zhengzhou, Not set
Local Institution - 0305, Bogotá, Cundinamarca
Local Institution - 0306, Montería, Córdoba
Local Institution - 0251, Hradec Kralove, Hradec Králové
Local Institution - 0250, Olomouc, Not set
Local Institution - 0356, Copenhagen, Hovedstaden
Local Institution - 0219, Pessac, Aquitaine
Local Institution - 0217, Caen, Calvados
Local Institution - 0212, Dijon, Côte-d'Or
Local Institution - 0341, Besançon, Doubs
Local Institution - 0221, Brest, Finistère
Local Institution - 0216, Toulouse, Haute-Garonne
Local Institution - 0220, Montpellier, Hérault
Local Institution - 0222, Rennes, Ille-et-Vilaine
Local Institution - 0215, Saint-Herblain, Loire-Atlantique
Local Institution - 0211, Vandoeuvre lès Nancy, Meurthe-et-Moselle
Local Institution - 0224, Marseille, Provence-Alpes-Côte-d'Azur
Local Institution - 0223, Clermont-Ferrand, Puy-de-Dôme
Local Institution - 0214, Pierre-Bénite, Rhône
Local Institution - 0213, Créteil, Val-de-Marne
Local Institution - 0218, Paris, Not set
Local Institution - 0338, Tours, Not set
Local Institution - 0202, München, Bayern
Local Institution - 0209, Regensburg, Bayern
Local Institution - 0008, Patras, Achaḯa
Local Institution - 0005, Athens, Attikí
Local Institution - 0001, Athens, Attikí
Local Institution - 0009, Athens, Attikí
Local Institution - 0006, Thessaloniki, Kentrikí Makedonía
Local Institution - 0003, Larissa, Thessalía
Local Institution - 0285, Hksar, Not set
Local Institution - 0323, Shatin, Not set
Local Institution - 0290, Gyula, Békés
Local Institution - 0291, Gyöngyös, Heves
Local Institution - 0287, Farkasgyepu, Veszprém
Local Institution - 0288, Budapest, Not set
Local Institution - 0267, New Delhi, Delhi
Local Institution - 0263, Bangalore, Karnataka
Local Institution - 0344, Bengaluru, Karnataka
Local Institution - 0345, Mumbai, Maharashtra
Local Institution - 0266, Mumbai, Maharashtra
Local Institution - 0265, Hyderabad, Telangana
Local Institution - 0264, Varanasi, Uttar Pradesh
Local Institution - 0010, Kfar Saba, HaMerkaz
Local Institution - 0011, Ramat Gan, HaMerkaz
Local Institution - 0016, Afula, HaTsafon
Local Institution - 0014, Haifa, HaTsafon
Local Institution - 0017, Jerusalem, Yerushalayim
Local Institution - 0013, Jerusalem, Yerushalayim
Local Institution - 0105, Napoli, Campania
Local Institution - 0042, Aviano, Friuli-Venezia Giulia
Local Institution - 0037, Orbassano, Torino
Local Institution - 0044, Perugia, Umbria
Local Institution - 0098, Bologna, Not set
Local Institution - 0045, Milano, Not set
Local Institution - 0039, Milan, Not set
Local Institution - 0035, Ravenna, Not set
Local Institution - 0243, Nagoya, Aichi
Local Institution - 0236, Kashiwa, Chiba
Local Institution - 0334, Otashi, Gunma
Local Institution - 0233, Sapporo, Hokkaido
Local Institution - 0336, Himeji, Hyogo
Local Institution - 0247, Kobe, Hyogo
Local Institution - 0335, Shiwa-gun Yahaba-cho, Iwate
Local Institution - 0257, Kawasaki, Kanagawa
Local Institution - 0238, Yokohama, Kanagawa
Local Institution - 0241, Nankoku, Kochi
Local Institution - 0237, Matsusaka City, Mie
Local Institution - 0232, Sendai, Miyagi
Local Institution - 0240, Hirakata, Osaka
Local Institution - 0245, Hidaka, Saitama
Local Institution - 0235, Shimotsuga, Tochigi
Local Institution - 0234, Bunkyo-ku, Tokyo
Local Institution - 0242, Ube, Yamaguchi
Local Institution - 0246, Fukuoka, Not set
Local Institution - 0244, Okayama, Not set
Local Institution - 0239, Osaka, Not set
Local Institution - 0272, Cheongju-si, Chungcheongbuk-do [Chungbuk]
Local Institution - 0271, Goyang-si, Kyǒnggi-do
Local Institution - 0273, Seongnam, Kyǒnggi-do
Local Institution - 0270, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0269, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0268, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0274, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0390, Kuching, Sarawak
Local Institution - 0413, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur
Local Institution - 0293, Mexico City, Distrito Federal
Local Institution - 0294, Mexico City, Distrito Federal
Local Institution - 0296, Guadalajara, Jalisco
Local Institution - 0298, Monterrey, Nuevo León
Local Institution - 0297, Oaxaca de Juarez, Oaxaca
Local Institution - 0327, Chihuahua, Not set
Local Institution - 0230, Arnhem, Not set
Local Institution - 0249, Groningen, Not set
Local Institution - 0261, Warsaw, Mazowieckie
Local Institution - 0259, Kraków, Małopolskie
Local Institution - 0258, Prabuty, Pomorskie
Local Institution - 0262, Poznań, Wielkopolskie
Local Institution - 0260, Bydgoszcz, Not set
Local Institution - 0021, Bucharest, București
Local Institution - 0019, Florești, Cluj
Local Institution - 0025, Craiova, Dolj
Local Institution - 0027, Otopeni, Ilfov
Local Institution - 0030, Ploiești, Prahova
Local Institution - 0020, Bucharest, Not set
Local Institution - 0022, Cluj, Not set
Local Institution - 0023, Cluj, Not set
Local Institution - 0031, Iași, Not set
Local Institution - 0026, Iași, Not set
Local Institution - 0116, Barcelona, Barcelona [Barcelona]
Local Institution - 0248, Hospitalet, Barcelona [Barcelona]
Local Institution - 0253, Barcelona, Catalunya [Cataluña]
Local Institution - 0118, Madrid, Madrid, Comunidad De
Local Institution - 0254, Madrid, Madrid, Comunidad De
Local Institution - 0252, Majadahonda, Madrid, Comunidad De
Local Institution - 0117, Málaga, Not set
Local Institution - 0256, Sevilla, Not set
Local Institution - 0255, València, Not set
Local Institution - 0114, Tainan City, Tainan
Local Institution - 0111, Tainan, Not set
Local Institution - 0113, Taipei, Not set
Local Institution - 0115, Taipei, Not set
Local Institution - 0112, Taoyuan, Not set
Local Institution - 0411, Bangkok, Not set
Local Institution - 0412, Bangkok, Not set
Local Institution - 0349, Izmir, Karsiyaka, İzmir
Local Institution - 0318, Adana, Not set
Local Institution - 0317, Adana, Not set
Local Institution - 0321, Ankara, Not set
Local Institution - 0350, Antalya, Not set
Local Institution - 0320, Bursa, Not set
Local Institution - 0319, Edirne, Not set
Local Institution - 0228, London, London, City Of
Conditions: Metastatic Non-small Cell Lung Cancer With MTAP Deletion
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
Recruiting
The purpose of this study is to compare sacituzumab tirumotecan as a single agent, and in combination with pembrolizumab, versus Treatment of Physician's Choice (TPC) in participants with hormone receptor positive/human epidermal growth factor receptor-2 negative (HR+/HER2-) unresectable locally advanced, or metastatic, breast cancer.
The primary hypotheses are that sacituzumab tirumotecan as a single agent and sacituzumab tirumotecan plus pembrolizumab are superior to TPC with respect to progr... Read More
The purpose of this study is to compare sacituzumab tirumotecan as a single agent, and in combination with pembrolizumab, versus Treatment of Physician's Choice (TPC) in participants with hormone receptor positive/human epidermal growth factor receptor-2 negative (HR+/HER2-) unresectable locally advanced, or metastatic, breast cancer.
The primary hypotheses are that sacituzumab tirumotecan as a single agent and sacituzumab tirumotecan plus pembrolizumab are superior to TPC with respect to progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) by blinded independent central review (BICR) in all participants. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Ironwood Cancer & Research Centers ( Site 0066), Chandler, Arizona +241 locations
Ironwood Cancer & Research Centers ( Site 0066), Chandler, Arizona
Banner MD Anderson Cancer Center-Oncology ( Site 0004), Gilbert, Arizona
Providence Medical Foundation-Oncology ( Site 0020), Fullerton, California
Moores Cancer Center ( Site 0059), La Jolla, California
Cancer and Blood Specialty Clinic ( Site 0001), Los Alamitos, California
University of Colorado Anschutz Medical Campus ( Site 0061), Aurora, Colorado
UCHealth Cherry Creek Medical Center ( Site 0094), Denver, Colorado
University of Colorado Health - Highlands Ranch Hospital ( Site 0095), Highlands Ranch, Colorado
Yale Cancer Center ( Site 0060), New Haven, Connecticut
Stamford Hospital ( Site 0049), Stamford, Connecticut
AdventHealth Altamonte Springs ( Site 0021), Altamonte Springs, Florida
University of Florida College of Medicine ( Site 0063), Gainesville, Florida
Orlando Health Cancer Institute ( Site 0011), Orlando, Florida
Archbold Memorial Hospital-Lewis Hall Singletary Oncology Center ( Site 0032), Thomasville, Georgia
University of Chicago Medical Center ( Site 0067), Chicago, Illinois
Saint Elizabeth Medical Center Edgewood-Cancer Care Center ( Site 0053), Edgewood, Kentucky
Mary Bird Perkins Cancer Center-Breast & GYN Pavilion ( Site 0042), Baton Rouge, Louisiana
Greenebaum Comprehensive Cancer Center ( Site 0036), Baltimore, Maryland
Mercy Medical Center - Baltimore-Medical Oncology and Hematology ( Site 0028), Baltimore, Maryland
Holy Cross Hospital ( Site 0073), Silver Spring, Maryland
Dana-Farber Cancer Institute-Breast Oncology Center ( Site 0037), Boston, Massachusetts
Henry Ford Health ( Site 0002), Detroit, Michigan
Saint Luke's Cancer Institute ( Site 0027), Kansas City, Missouri
Washington University School of Medicine ( Site 0076), Saint Louis, Missouri
Laura and Isaac Perlmutter Cancer Center-Hematology and Oncology ( Site 0068), New York, New York
Hematology Oncology Associates of Rockland ( Site 0054), Nyack, New York
Stony Brook University-Cancer Center ( Site 0034), Stony Brook, New York
Levine Cancer Institute ( Site 0014), Charlotte, North Carolina
Zangmeister Cancer Center ( Site 7000), Columbus, Ohio
Providence Portland Medical Center ( Site 0044), Portland, Oregon
Providence St. Vincent Medical Center ( Site 0081), Portland, Oregon
Thomas Jefferson University - Clinical Research Institute ( Site 0056), Philadelphia, Pennsylvania
Texas Oncology-Dallas Presbyterian Hospital ( Site 8000), Dallas, Texas
The Center for Cancer and Blood Disorders ( Site 0041), Fort Worth, Texas
Texas Oncology - San Antonio ( Site 8002), San Antonio, Texas
The University of Texas Health Science Center at Tyler dba UT Health East Texas HOPE Cancer Center ( Site 0057), Tyler, Texas
Inova Schar Cancer Institute ( Site 0025), Fairfax, Virginia
Bon Secours St. Francis Medical Center-Oncology Research ( Site 0015), Midlothian, Virginia
VCU Health Adult Outpatient Pavillion ( Site 0070), Richmond, Virginia
Oncology and Hematology Associates of Southwest Virginia (BRCC) ( Site 8001), Roanoke, Virginia
University Hospital and UW Health Clinics-Carbone Cancer Center ( Site 0040), Madison, Wisconsin
Instituto Alexander Fleming-Alexander Fleming ( Site 0382), Ciudad Autónoma de Buenos Aires, Caba
Fundacion Estudios Clinicos-Oncology ( Site 0384), Rosario, Santa Fe
Hospital Aleman-Oncology ( Site 0386), Buenos Aires, Not set
Centro de Educación Médica e Investigaciones clínicas "Dr. Norberto Quirno" (CEMIC) ( Site 0383), Buenos Aires, Not set
Hospital Italiano de Córdoba ( Site 0385), Cordoba, Not set
Fundación CORI para la Investigación y Prevención del Cáncer ( Site 0387), La Rioja, Not set
Macquarie University-MQ Health Clinical Trials Unit ( Site 2002), Macquarie University, New South Wales
Westmead Hospital ( Site 2000), Westmead, New South Wales
Frankston Hospital-Oncology and Haematology ( Site 2003), Frankston, Victoria
Fiona Stanley Hospital-Medical Oncology ( Site 2004), Murdoch, Western Australia
Institut Jules Bordet-Medicine Oncology ( Site 1104), Anderlecht, Bruxelles-Capitale, Region De
Cliniques universitaires Saint-Luc-Medical Oncology ( Site 1103), Brussels, Bruxelles-Capitale, Region De
Jessa Ziekenhuis-Limburgs Oncologisch Centrum ( Site 1105), Hasselt, Limburg
AZ Maria Middelares-IKG ( Site 1106), Gent, Oost-Vlaanderen
Université Catholique de Louvain-Namur - Centre Hospitalier -Oncology ( Site 1107), Namur, Not set
Oncoclínica Oncologistas Associados-Clinical Research ( Site 0407), Teresina, Piaui
Hospital Moinhos de Vento ( Site 0403), Porto Alegre, Rio Grande Do Sul
Hospital do Câncer Mãe de Deus ( Site 0404), Porto Alegre, Rio Grande Do Sul
Instituto de Oncologia Saint Gallen ( Site 0412), Santa Cruz do Sul, Rio Grande Do Sul
Instituto do Câncer Brasil - Unidade Taubaté ( Site 0408), Taubaté, Sao Paulo
IBCC - Núcleo de Pesquisa e Ensino ( Site 0401), Sao Paulo, Not set
BC Cancer Surrey ( Site 0315), Surrey, British Columbia
Southlake Regional Health Centre ( Site 0311), Newmarket, Ontario
Princess Margaret Cancer Centre ( Site 0310), Toronto, Ontario
CIUSSS de l'Est-de-l'Île-de-Montréal ( Site 0301), Montreal, Quebec
Jewish General Hospital ( Site 0303), Montreal, Quebec
Centre intégré de santé et de services sociaux du Bas Saint-Laurent- Hôpital régional de Rimouski ( Site 0308), Rimouski, Quebec
CHU de Quebec Universite Laval - Hopital du Saint-Sacrement ( Site 0302), Quebec, Not set
Oncovida ( Site 0453), Santiago., Region M. De Santiago
Clínica RedSalud Vitacura ( Site 0455), Santiago., Region M. De Santiago
FALP-UIDO ( Site 0451), Santiago, Region M. De Santiago
Pontificia Universidad Catolica de Chile ( Site 0454), Santiago, Region M. De Santiago
Bradfordhill ( Site 0452), Santiago, Region M. De Santiago
Bradford Hill Norte ( Site 0456), Antofagasta, Not set
Fundacion Colombiana de Cancerología Clinica Vida ( Site 0506), Medellín, Antioquia
Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 0501), Valledupar, Cesar
IMAT S.A.S ( Site 0502), Monteria., Cordoba
FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0507), Bogota, Distrito Capital De Bogota
Fundación Valle del Lili ( Site 0508), Cali, Valle Del Cauca
CIMCA ( Site 0551), San José, San Jose
Hospital Metropolitano - Sede Lindora ( Site 0550), Santa Ana, San Jose
ICIMED ( Site 0552), San Jose, Not set
Nemocnice Ceske Budejovice-Onkologicke oddeleni ( Site 1138), Ceske Budejovice, Jihocesky Kraj
Fakultni nemocnice Ostrava-Klinika onkologicka ( Site 1134), Ostrava-Poruba, Moravskoslezsky Kraj
Fakultni nemocnice Olomouc-Onkologicka klinika ( Site 1132), Olomouc, Olomoucky Kraj
Fakultni nemocnice v Motole-Onkologicka klinika 2. LF UK a FN Motol ( Site 1136), Praha, Praha 5
Fakultni nemocnice Kralovske Vinohrady-Onkologická klinika ( Site 1135), Praha 10, Not set
Rigshospitalet ( Site 1180), Copenhagen, Hovedstaden
Nordsjællands Hospital - Hillerød ( Site 1184), Hillerod, Hovedstaden
Næstved Sygehus ( Site 1182), Naestved, Sjaelland
Odense Universitetshospital ( Site 1181), Odense C, Syddanmark
Vejle Sygehus ( Site 1183), Vejle, Syddanmark
Centre François Baclesse ( Site 1250), Caen, Calvados
Centre de Cancérologie du Grand Montpellier ( Site 1244), Montpellier, Languedoc-Roussillon
Hôpital privé du Confluent SAS-Service d'oncologie médicale ( Site 1242), Nantes, Loire-Atlantique
Pitie Salpetriere University Hospital ( Site 1249), Paris, Orne
Hopital Prive Jean Mermoz-Oncology ( Site 1246), Lyon, Rhone-Alpes
Centre Hospitalier Universitaire de Poitiers-Pôle régional de cancérologie ( Site 1243), Poitiers, Vienne
Institut Curie-Oncology medical Department ( Site 1240), Paris, Not set
SRH Wald-Klinikum Gera-Zentrum für klinische Studien ( Site 1315), Gera, Thuringen
Helios Klinikum Berlin-Buch-Klinik für Gynäkologie und Geburtshilfe ( Site 1314), Berlin, Not set
Errikos Dunant Hospital Center ( Site 1348), Athens, Attiki
Aretaieio Hospital Oncology Unit ( Site 1345), Athens, Attiki
Hygeia Hospital ( Site 1346), Marousi, Attiki
University General Hospital of Larissa ( Site 1343), Larissa, Thessalia
Agios Loukas Clinic ( Site 1347), Thessaloniki, Not set
European Interbalkan Medical Center ( Site 1341), Thessaloniki, Not set
Queen Mary Hospital ( Site 2040), Hksar, Not set
Prince of Wales Hospital ( Site 2041), Shatin, Not set
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Onkoterápiás Klinika ( Site 1379), Szeged, Csongrad
Somogy Vármegyei Kaposi Mór Oktató Kórház-Oncology center ( Site 1371), Kaposvár, Somogy
Zala Vármegyei Szent Rafael Kórház-Onkológiai osztály ( Site 1372), Zalaegerszeg, Zala
Semmelweis Egyetem-Belgyógyászati és Onkológiai Klinika ( Site 1381), Budapest, Not set
Budapesti Uzsoki Utcai Kórház-Onkoradiológiai Osztály ( Site 1373), Budapest, Not set
Debreceni Egyetem Klinikai Kozpont-Onkológiai Klinika ( Site 1375), Debrecen, Not set
All India Institute of Medical Sciences ( Site 2051), New Delhi, Delhi
Rajiv Gandhi Cancer Institute And Research Centre-Department of Clinical Research ( Site 2052), New Delhi, Delhi
Tata Memorial Hospital-Medical Oncology ( Site 2053), Mumbai, Maharashtra
Kokilaben Dhirubhai Ambani Hospital & Medical Research Institute-Centre for cancer ( Site 2056), Mumbai, Maharashtra
Bon Secours Cork Hospital ( Site 1422), Cork, Not set
St. Vincent's University Hospital-Medical Oncology Research Department ( Site 1420), Dublin, Not set
Mater Misericordiae University Hospital-Clinical Trials Research Unit ( Site 1423), Dublin, Not set
Rambam Health Care Campus-Oncology Division ( Site 1452), Haifa, Not set
Hadassah Medical Center ( Site 1451), Jerusalem, Not set
Rabin Medical Center ( Site 1453), Petah Tikva, Not set
Sheba Medical Center ( Site 1450), Ramat Gan, Not set
IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori" ( Site 1480), Meldola, Forli-Cesena
CRO-IRCCS ( Site 1478), Aviano, Friuli-Venezia Giulia
Istituto Europeo di Oncologia IRCCS-Divisione di Senologia Medica ( Site 1475), Milano, Lombardia
Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1472), Milan, Lombardia
Istituto Clinico Humanitas ( Site 1476), Rozzano, Milano
IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola ( Site 1474), Bologna, Not set
Ospedale San Martino ( Site 1479), Genova, Not set
Ospedale San Raffaele-Oncologia Medica ( Site 1471), Milano, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 1477), Roma, Not set
Nagoya City University Hospital ( Site 2474), Nagoya, Aichi
Hokkaido University Hospital ( Site 2460), Sapporo, Hokkaido
Tokai University Hospital ( Site 2473), Isehara, Kanagawa
St. Marianna University Hospital ( Site 2465), Kawasaki, Kanagawa
Kitasato University Hospital ( Site 2471), Sagamihara, Kanagawa
Kanagawa Cancer Center ( Site 2472), Yokohama, Kanagawa
Mie University Hospital ( Site 2483), Tsu, Mie
Tohoku University Hospital ( Site 2482), Sendai, Miyagi
The University of Osaka Hospital ( Site 2476), Suita, Osaka
Saitama Medical University International Medical Center ( Site 2462), Hidaka, Saitama
Juntendo University Hospital ( Site 2468), Bunkyo, Tokyo
Cancer Institute Hospital of JFCR ( Site 2464), Koto, Tokyo
Showa Medical University Hospital ( Site 2466), Shinagawa, Tokyo
Tokyo Medical University Hospital ( Site 2467), Shinjuku, Tokyo
National Center for Global Health and Medicine ( Site 2469), Shinjuku, Tokyo
Fukushima Medical University Hospital ( Site 2461), Fukushima, Not set
Gifu University Hospital ( Site 2486), Gifu, Not set
Hiroshima City Hiroshima Citizens Hospital ( Site 2478), Hiroshima, Not set
Social medical corporation Hakuaikai Sagara Hospital ( Site 2481), Kagoshima, Not set
Kumamoto University Hospital ( Site 2480), Kumamoto, Not set
Kyoto University Hospital ( Site 2475), Kyoto, Not set
Okayama University Hospital ( Site 2485), Okayama, Not set
Osaka International Cancer Institute ( Site 2477), Osaka, Not set
Seoul National University Hospital-Internal Medicine ( Site 2353), Seoul, Not set
Severance Hospital, Yonsei University Health System-Medical oncology ( Site 2350), Seoul, Not set
Asan Medical Center-Department of Oncology ( Site 2352), Seoul, Not set
Samsung Medical Center-Division of Hematology/Oncology ( Site 2351), Seoul, Not set
Hospital Sultan Ismail ( Site 2153), Johor Bahru, Johor
Sarawak General Hospital ( Site 2154), Kuching, Sarawak
Pantai Hospital Kuala Lumpur ( Site 2151), Kuala Lumpur, Not set
Health Pharma Professional Research S.A. de C.V: ( Site 0598), Ciudad de México, Distrito Federal
Grupo Médico ASSET-Clinical Research ( Site 0596), Mexico City, Distrito Federal
CIO - Centro de Inmuno-Oncología de Occidente ( Site 0592), Guadalajara, Jalisco
Hospital Universitario "Dr. Jose Eleuterio Gonzalez"-Servicio de Oncología ( Site 0590), Monterrey, Nuevo Leon
CENTRO MEDICO ZAMBRANO HELLION-Centro de Cáncer de Mama ( Site 0595), San Pedro Garza Garcia, Nuevo Leon
Ziekenhuis Rijnstate-Rijnstate Centrum Oncologisch Onderzoek ( Site 1524), Arnhem, Gelderland
Maastricht UMC+-Medical Oncology ( Site 1522), Maastricht, Limburg
Amphia Ziekenhuis, locatie Breda Molengracht-oncologie ( Site 1523), Breda, Noord-Brabant
Catharina Ziekenhuis ( Site 1526), Eindhoven, Noord-Brabant
Nederlands Kanker Instituut - Antoni van Leeuwenhoek (NKI-AVL)-medical oncology ( Site 1520), Amsterdam, Noord-Holland
Isala, locatie Zwolle ( Site 1525), Zwolle, Overijssel
Meander Medisch Centrum ( Site 1521), Amersfoort, Utrecht
Auckland City Hospital ( Site 2031), Auckland, Not set
Clinica Vallesur - AUNA ( Site 0652), Arequipa, Ariqipa
Hospital Militar Central Luis Arias Schereiber ( Site 0651), Jesús María, Lima
Oncosalud ( Site 0650), Lima, Muni Metro De Lima
IPOR Instituto Peruano de Oncología & Radioterapia ( Site 0653), Lima, Not set
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 1582), Bydgoszcz, Kujawsko-pomorskie
Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 1584), Siedlce, Mazowieckie
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworów Piersi i Chirurgii ( Site 1580), Warszawa, Mazowieckie
Mazowiecki Szpital Onkologiczny ( Site 1581), Wieliszew, Mazowieckie
Mrukmed-Mrukmed ( Site 1592), Rzeszow, Podkarpackie
Bialostockie Centrum Onkologii ( Site 1585), Bialystok, Podlaskie
Szpitale Pomorskie Sp. z o. o.-Oddział Onkologii Klinicznej ( Site 1593), Gdynia, Pomorskie
Narodowy Instytut Onkologii - Oddzial w Gliwicach-Centrum Diagnostyki i Leczenia Chorob Piersi ( Site 1590), Gliwice, Slaskie
Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zakl-Klinika Onkologii Klinicznej, Dzial Ch ( Site 1595), Kielce, Swietokrzyskie
Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie-Oddzial Dzienny Chemioterapii ( Site 1583), Koszalin, Zachodniopomorskie
Zachodniopomorskie Centrum Onkologii ( Site 1588), Szczecin, Zachodniopomorskie
Unidade Local de Saude Amadora/Sintra - Hospital Prof Dr Fernando Fonseca ( Site 1663), Lisbon, Lisboa
Unidade Local de Saude de Santa Maria - Hospital de Santa Maria ( Site 1661), Lisboa, Not set
Instituto Português de Oncologia do Porto Francisco Gentil, EPE ( Site 1662), Porto, Not set
Puerto Rico Medical Research Center LLC ( Site 0675), Hato Rey, Not set
UPR Comprehensive Cancer Center-Comprehensive Cancer Center Hospital ( Site 0677), San Juan, Not set
Spitalul Clinic Filantropia ( Site 1703), București, Bucuresti
SC Radiotherapy Center Cluj SRL-Oncologie Medicala ( Site 1702), Florești, Cluj
Centrul Medical Neolife- Baneasa ( Site 1704), Bucuresti, Not set
Institutul Oncologic Cluj ( Site 1701), Cluj, Not set
National University Hospital ( Site 2250), Singapore, Central Singapore
Mount Alvernia ICON Cancer Center ( Site 2251), Singapore, North East
CANCERCARE LANGENHOVEN DRIVE ONCOLOGY CENTRE ( Site 2905), Port Elizabeth, Eastern Cape
Curo Oncology ( Site 2908), Pretoria, Gauteng
Sandton Oncology Medical Group (Pty) Ltd ( Site 2911), Sandton, Gauteng
Cancercare Rondebosch Oncology-Clinical trials ( Site 2904), Rondebosch, Western Cape
HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID ( Site 1758), Pozuelo de Alarcon, Madrid
HOSPITAL CLINICO DE VALENCIA-Oncology ( Site 1752), Valencia, Valenciana, Comunitat
Hospital Universitari Vall d'Hebron-Oncology ( Site 1750), Barcelona, Not set
Hospital Universitario Reina Sofia-Oncologia Medica ( Site 1754), Cordoba, Not set
Hospital Beata María Ana-oncology ( Site 1755), Madrid, Not set
HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON-ONCOLOGY ( Site 1756), Madrid, Not set
Hospital Universitario Virgen Macarena ( Site 1757), Sevilla, Not set
Karolinska Universitetssjukhuset Solna ( Site 1801), Stockholm, Stockholms Lan
Akademiska sjukhuset ( Site 1802), Uppsala, Uppsala Lan
Södra Älvsborgs Sjukhus Borås ( Site 1803), Borås, Vastra Gotalands Lan
University Hospital Basel-Gynecology & Gynecologic Oncology ( Site 1844), Basel, Basel-Stadt
Spital Thun ( Site 1840), Thun, Berne
Brust-Zentrum ( Site 1841), Zürich, Zurich
Changhua Christian Hospital ( Site 2410), Changhua, Not set
Chang Gung Memorial Hospital at Kaohsiung-Oncology and Hematology ( Site 2413), Kaohsiung, Not set
National Cheng Kung University Hospital-Surgery ( Site 2411), Tainan, Not set
National Taiwan University Hospital-Oncology ( Site 2415), Taipei, Not set
Mackay Memorial Hospital ( Site 2412), Taipei, Not set
Chang Gung Medical Foundation-Linkou Branch-General Surgery ( Site 2414), Taoyuan, Not set
Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi ( Site 1878), Yenimahalle, Ankara
Medipol Mega Universite Hastanesi-oncology ( Site 1875), Stanbul, Istanbul
Adana Medical Park Seyhan Hastanesi-Medikal Onkoloji ( Site 1876), Adana, Not set
Hacettepe Universite Hastaneleri-oncology hospital ( Site 1870), Ankara, Not set
Memorial Ankara Hastanesi-Medical Oncology ( Site 1874), Ankara, Not set
Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 1871), Ankara, Not set
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 1872), Istanbul, Not set
Samsun Medical Park Hastanesi-medical oncology ( Site 1873), Samsun, Not set
North West Cancer Centre ( Site 1944), Londonderry, Derry And Strabane
The Royal Cornwall Hospital ( Site 1943), Truro, England
St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 1940), London, London, City Of
University College London Hospital-Cancer Clinical Trials Unit ( Site 1942), London, London, City Of
Blackpool Victoria Hospital ( Site 1941), Blackpool, Not set
City Hospital, Nottingham University Hospitals NHS Trust ( Site 1945), Nottingham, Not set
Conditions: Breast Neoplasms
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
Recruiting
The goal of this study is to learn if people who receive intismeran autogene and pembrolizumab after surgery are cancer-free longer than people who receive placebo and pembrolizumab. Researchers want to know if giving intismeran autogene and pembrolizumab after surgery can help prevent the cancer from coming back in people with non-small cell lung cancer (NSCLC) whose tumors did not respond completely to treatment before surgery (neoadjuvant treatment).
The goal of this study is to learn if people who receive intismeran autogene and pembrolizumab after surgery are cancer-free longer than people who receive placebo and pembrolizumab. Researchers want to know if giving intismeran autogene and pembrolizumab after surgery can help prevent the cancer from coming back in people with non-small cell lung cancer (NSCLC) whose tumors did not respond completely to treatment before surgery (neoadjuvant treatment). Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/13/2025
Locations: Banner MD Anderson Cancer Center ( Site 0181), Gilbert, Arizona +155 locations
Banner MD Anderson Cancer Center ( Site 0181), Gilbert, Arizona
Providence St. Jude Medical Center ( Site 0106), Fullerton, California
UCSF Medical Center at Mission Bay ( Site 0178), San Francisco, California
UCHealth Memorial Hospital Central ( Site 0125), Colorado Springs, Colorado
Banner MD Anderson Cancer Center at North Colorado Medical Center ( Site 0207), Greeley, Colorado
Beacon Cancer Care ( Site 0127), Post Falls, Idaho
The University of Chicago Medical Center ( Site 0118), Chicago, Illinois
Massachusetts General Hospital ( Site 0136), Boston, Massachusetts
Dana Farber Cancer Hospital ( Site 0155), Boston, Massachusetts
Ellis Fischel Cancer Center ( Site 0133), Columbia, Missouri
Lake Regional Hospital-Cancer Center ( Site 0123), Osage Beach, Missouri
Montefiore Medical Center ( Site 0160), Bronx, New York
Roswell Park Cancer Institute ( Site 0184), Buffalo, New York
Hematology-Oncology Associates of CNY ( Site 0164), East Syracuse, New York
Icahn School of Medicine at Mount Sinai ( Site 0116), New York, New York
Memorial Sloan Kettering Cancer Center ( Site 0137), New York, New York
SUNY Upstate Cancer Center ( Site 0140), Syracuse, New York
Westchester Medical Center ( Site 0196), Valhalla, New York
University of Cincinnati Medical Center ( Site 0119), Cincinnati, Ohio
St. Lukes Hospital and Health Network ( Site 0186), Bethlehem, Pennsylvania
Thompson Cancer Survival Center ( Site 0168), Knoxville, Tennessee
MD Anderson Cancer Center ( Site 0150), Houston, Texas
Memorial Hermann Cancer Center ( Site 0172), Houston, Texas
O'Quinn Medical Tower at McNair Campus ( Site 0131), Houston, Texas
The University of Texas Health Science Center at Tyler dba UT Health East Texas HOPE Cancer Center ( Site 0148), Tyler, Texas
Swedish Cancer Institute ( Site 0143), Seattle, Washington
Virginia Mason Franciscan Health - St. Michael Cancer Center ( Site 0192), Silverdale, Washington
CEMIC ( Site 2454), Caba., Buenos Aires
Fundacion Intecnus ( Site 2456), San Carlos de Bariloche, Rio Negro
Centro Médico IPAM ( Site 2452), Rosario, Santa Fe
Instituto Medico Especializado Alexander Fleming ( Site 2457), Buenos Aires, Not set
Instituto Oncologico de Cordoba -IONC ( Site 2455), Cordoba, Not set
Calvary Mater Newcastle ( Site 2106), Waratah, New South Wales
Tasman Oncology Research ( Site 2104), Southport, Queensland
Princess Alexandra Hospital ( Site 2102), Wooloongabba, Queensland
Grampians Health ( Site 2101), Ballarat, Victoria
One Clinical Research ( Site 2103), Nedlands, Western Australia
Cliniques Universitaires Saint-Luc ( Site 1203), Bruxelles, Bruxelles-Capitale, Region De
Jessa Ziekenhuis ( Site 1204), Hasselt, Limburg
UZ Gent ( Site 1201), Gent, Oost-Vlaanderen
CRIO - CENTRO REGIONAL INTEGRADO DE ONCOLOGIA ( Site 2502), Fortaleza, Ceara
Liga Norte Riograndense Contra o Cancer ( Site 2513), Natal, Rio Grande Do Norte
Hospital Tacchini ( Site 2506), Bento Goncalves, Rio Grande Do Sul
Hospital de Clínicas de Passo Fundo ( Site 2504), Passo Fundo, Rio Grande Do Sul
Hospital Moinhos de Vento ( Site 2510), Porto Alegre, Rio Grande Do Sul
Hospital Nossa Senhora Da Conceicao ( Site 2512), Porto Alegre, Rio Grande Do Sul
Instituto de Oncologia Saint Gallen ( Site 2507), Santa Cruz do Sul, Rio Grande Do Sul
Hospital de Amor - Barretos ( Site 2511), Barretos, Sao Paulo
Instituto Nacional de Câncer - INCA ( Site 2501), Rio de Janeiro, Not set
MBAL Uni Hospital ( Site 1253), Panagyurishte, Pazardzhik
MHAT - Heart and Brain ( Site 1252), Pleven, Not set
Queen Elizabeth II Health Sciences Centre ( Site 1101), Halifax, Nova Scotia
Hamilton Health Sciences - Juravinski Site ( Site 1104), Hamilton, Ontario
Kingston Health Sciences Centre-Kingston General Hospital Site ( Site 1105), Kingston, Ontario
Lakeridge Health ( Site 1107), Oshawa, Ontario
McGill University Health Centre ( Site 1103), Montréal, Quebec
IUCPQ ( Site 1112), Québec, Quebec
FALP ( Site 2551), Santiago., Region M. De Santiago
Orlandi Oncologia ( Site 2555), Santiago, Region M. De Santiago
Clínica RedSalud Vitacura ( Site 2556), Santiago, Region M. De Santiago
Bradfordhill ( Site 2552), Santiago, Region M. De Santiago
ONCOCENTRO APYS ( Site 2554), Viña del Mar, Valparaiso
IMAT S.A.S ( Site 2602), Monteria, Cordoba
FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 2603), Bogota, Distrito Capital De Bogota
Hospital Universitario San Ignacio ( Site 2610), Bogota, Distrito Capital De Bogota
Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia ( Site 2604), Bogota, Distrito Capital De Bogota
Oncologos del Occidente ( Site 2608), Pereira, Risaralda
Fundacion Valle del Lili- CIC ( Site 2601), Cali, Valle Del Cauca
Oulun yliopistollinen sairaala ( Site 1301), Oulu, Pohjois-Pohjanmaa
Turku University Hospital ( Site 1303), Turku, Varsinais-Suomi
CHU Besançon ( Site 1358), Besancon, Franche-Comte
Institut De Cancerologie De L Ouest ( Site 1357), Saint Herblain, Loire-Atlantique
CENTRE LEON BERARD ( Site 1351), Lyon CEDEX 08, Rhone
Marienhaus Klinikum Mainz ( Site 1403), Mainz, Rheinland-Pfalz
UNIVERSITY HOSPITAL OF PATRAS-DIVISION OF ONCOLOGY ( Site 1452), Patras, Achaia
Errikos Dunant Hospital Center ( Site 1457), Athens, Attiki
THORACIC GENERAL HOSPITAL OF ATHENS "I SOTIRIA"-3rd Dept of Internal Medicine and Laboratory, Oncol ( Site 1451), Athens, Attiki
Metropolitan Hospital ( Site 1459), Athens, Attiki
ATTIKON GENERAL UNIVERSITY HOSPITAL ( Site 1460), Chaidari, Attiki
University General Hospital of Herakleion ( Site 1458), Herakleion., Irakleio
University General Hospital of Larissa-Oncology Clinic ( Site 1453), Larissa, Thessalia
Papageorgiou General Hospital of Thessaloniki ( Site 1454), Thessaloniki, Not set
Petz Aladár Megyei Oktató Kórház ( Site 1502), Gyor, Gyor-Moson-Sopron
Debreceni Egyetem Altalanos Orvostudomanyi Kar Tudogyogyaszati Tanszek ( Site 1508), Debrecen, Hajdu-Bihar
Mátrai Gyógyintézet ( Site 1504), Mátraháza, Heves
Reformatus Pulmonologiai Centrum-Onkopulmonologiai Jarobeteg Centrum ( Site 1505), Törökbálint, Pest
Somogy Vármegyei Kaposi Mór Oktató Kórház-Oncology center ( Site 1507), Kaposvár, Somogy
Orszagos Koranyi Pulmonologiai Intezet ( Site 1501), Budapest, Not set
Rambam Health Care Campus ( Site 1603), Haifa, Not set
Shaare Zedek Medical Center ( Site 1601), Jerusalem, Not set
Hadassah Medical Center ( Site 1605), Jerusalem, Not set
Sheba Medical Center ( Site 1602), Ramat Gan, Not set
Hospital of the University of Occupational and Environmental Health, Japan ( Site 1166), Kitakyushu, Fukuoka
St. Marianna University Hospital ( Site 1159), Kawasaki, Kanagawa
Kindai University Hospital ( Site 1162), Osakasayama, Osaka
Shizuoka Cancer Center ( Site 1160), Sunto-gun, Shizuoka
National Cancer Center Hospital ( Site 1156), Chuo, Tokyo
Tokyo Medical University Hospital ( Site 1157), Shinjuku, Tokyo
Chiba University Hospital ( Site 1154), Chiba, Not set
National Hospital Organization Kyushu Cancer Center ( Site 1167), Fukuoka, Not set
Fukushima Medical University Hospital ( Site 1151), Fukushima, Not set
Hiroshima University Hospital ( Site 1165), Hiroshima, Not set
Okayama University Hospital ( Site 1164), Okayama, Not set
Wakayama Medical University Hospital ( Site 1163), Wakayama, Not set
National Cancer Center ( Site 2305), Goyang-si, Kyonggi-do
The Catholic University of Korea St. Vincent s Hospital ( Site 2301), Suwonsi, Kyonggi-do
Ajou University Hospital ( Site 2306), Suwon, Kyonggi-do
Seoul National University Hospital ( Site 2303), Seoul, Not set
Severance Hospital Yonsei University Health System ( Site 2302), Seoul, Not set
Samsung Medical Center ( Site 2304), Seoul, Not set
Seoul St. Mary's Hospital ( Site 2307), Seoul, Not set
Medisch Centrum Leeuwarden ( Site 1702), Leeuwarden, Fryslan
Radboudumc ( Site 1706), Nijmegen, Gelderland
Dunedin Hospital ( Site 2202), Dunedin, Otago
Aliada ( Site 2753), Lima, Not set
Detecta Clínica ( Site 2751), Lima, Not set
Krakowski Szpital Specjalistyczny im. Jana Pawla II ( Site 1756), Krakow, Malopolskie
Instytut Gruźlicy i Chorób Płuc w Warszawie ( Site 1764), Warszawa, Mazowieckie
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 1759), Przemysl, Podkarpackie
Uniwersyteckie Centrum Kliniczne ( Site 1758), Gdansk, Pomorskie
Swietokrzyskie Centrum Onkologii. ( Site 1754), Kielce, Swietokrzyskie
Warmińsko - Mazurskie Centrum Chorób Płuc w Olsztynie ( Site 1760), Olsztyn, Warminsko-mazurskie
Wielkopolskie Centrum Pulmonologii i Torakochirurgii ( Site 1763), Poznan, Wielkopolskie
Centrul Medical Medicover Victoria ( Site 1802), Bucharest, Bucuresti
Institutul Regional de Oncologie ( Site 1804), Iasi, Not set
National Cancer Centre Singapore ( Site 2251), Singapore, Central Singapore
Tan Tock Seng Hospital ( Site 2252), Singapore, Central Singapore
Hospital Clinic de Barcelona ( Site 1919), Barcelona, Cataluna
Complejo Hospitalario Universitario A Coruna ( Site 1916), A Coruña, La Coruna
Hospital Universitario Quiron Madrid ( Site 1913), Pozuelo de Alarcon, Madrid
Hospital Universitari Vall D Hebron ( Site 1910), Barcelona, Not set
Hospital Insular de Gran Canaria ( Site 1911), Canarias, Not set
Hospital General Universitario Gregorio Maranon ( Site 1912), Madrid, Not set
Hospital Quiron Malaga ( Site 1914), Malaga, Not set
Karolinska Universitetssjukhuset Solna ( Site 1951), Stockholm, Stockholms Lan
Chung Shan Medical University Hospital ( Site 2351), Taichung, Not set
China Medical University Hospital ( Site 2358), Taichung, Not set
National Cheng Kung University Hospital ( Site 2354), Tainan, Not set
National Taiwan University Cancer Center (NTUCC) ( Site 2360), Taipei, Not set
Mackay Memorial Hospital ( Site 2355), Taipei, Not set
Taipei Medical University Hospital ( Site 2352), Taipei, Not set
Koo Foundation Sun Yat-Sen Cancer Center ( Site 2359), Taipei, Not set
Taipei Veterans General Hospital ( Site 2357), Taipei, Not set
Chang Gung Memorial Hospital ( Site 2361), Taoyuan, Not set
Hacettepe Universite Hastaneleri ( Site 2001), Sıhhiye, Ankara
Sakarya Universitesi Tip Fakultesi Hastanesi ( Site 2006), Adapazarı, Sakarya
Namık Kemal University Medical Faculty ( Site 2007), Tekirdag, Tekirdas
Ankara Bilkent Sehir Hastanesi ( Site 2002), Ankara, Not set
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi ( Site 2003), Istanbul, Not set
Bristol Haematology and Oncology Centre ( Site 2072), Bristol, Bristol, City Of
St Bartholomews Hospital ( Site 2052), London, London, City Of
Royal Free Hospital ( Site 2074), London, London, City Of
Guys Hospital ( Site 2057), London, London, City Of
Nottingham City Hospital ( Site 2058), Nottingham, Nottinghamshire
St James University Hospital ( Site 2055), Leeds, Not set
The Clatterbridge Cancer Centre ( Site 2069), Wirral, Not set
Conditions: Carcinoma, Non-Small-Cell Lung
Safety, Effectiveness, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
Recruiting
This is a Phase 2/3, multisite, randomized, open-label study in participants with first-line non-small cell lung cancer (NSCLC).
This study includes two substudies (substudy A and substudy B) that will recruit participants according to histological subtypes due to differences in chemotherapy choice for standard-of-care and type of NSCLC.
This is a Phase 2/3, multisite, randomized, open-label study in participants with first-line non-small cell lung cancer (NSCLC).
This study includes two substudies (substudy A and substudy B) that will recruit participants according to histological subtypes due to differences in chemotherapy choice for standard-of-care and type of NSCLC. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/13/2025
Locations: Alaska Oncology and Hematology, LLC, Anchorage, Alaska +98 locations
Alaska Oncology and Hematology, LLC, Anchorage, Alaska
Clermont Oncology Center, Clermont, Florida
Physicians Clinic of Iowa, Cedar Rapids, Iowa
Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, Iowa
Baptist Health, Lexington, Kentucky
SSM Health Cancer Care - St. Clare, Fenton, Missouri
Mary Lanning Healthcare (MLH) - Morrison Cancer Center (MCC), Hastings, Nebraska
Astera Cancer Care, East Brunswick, New Jersey
The Valley Hospital - Valley Health System - The Robert and Audrey Luckow Pavilion, Paramus, New Jersey
White Plains Hospital, White Plains, New York
Fletcher Hospital, Inc. dba AdventHealth Hendersonville, Hendersonville, North Carolina
University of Cincinnati Medical Center, Cincinnati, Ohio
University of Tennessee Medical Center, Knoxville, Tennessee
Baptist Cancer Center, Memphis, Tennessee
Millennium Research and Clinical Development, LLC, Houston, Texas
Royal Adelaide Hospital, Adelaide, Not set
Cairns Hospital, Cairns, Not set
Dubbo Hospital, Dubbo, Not set
Peninsula & South Eastern Haematology and Oncology Group, Frankston, Not set
Icon Cancer Centre Kurralta Park, Kurralta Park, Not set
Western Health Sunshine Hospital, St Albans, Not set
ICON Cancer Care - Townsville, Townsville, Not set
Cancer Care Wollongong Pty Limited, Wollongong, Not set
Universitair Ziekenhuis Leuven, Leuven, Not set
CHU HELORA, Hopital de Mons - Site Kennedy, Mons, Not set
Shandong University - Jinan Central Hospital, Jinan, Not set
Shanghai Chest Hospital, Shanghai, Not set
Cancer Hospital of Shantou University Medical College, Shantou, Not set
Centre Hospitalier Universitaire d'Angers (CHU Angers), Angers, Not set
Institut Bergonie - Centre Regional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest, Bordeaux, Not set
CHU Caen Normandie, Caen, Not set
Centre Francois Baclesse, Caen, Not set
Centre Hospitalier Intercommunal de Creteil (CHIC) - Centre de ressources et de competences pour la mucoviscidose (C.R.C.M.), Créteil, Not set
Institut de Cancerologie de l'Ouest (ICO)- CRLCC Rene Gauducheau, Saint-Herblain, Not set
Centre Hospitalier Intercommunal Toulon La Seyne Sur Mer (C.H.I.T.S) - Hospital Font-Pre, Toulon, Not set
Klinikum Esslingen GmbH, Esslingen, Not set
Asklepios Fachkliniken Muenchen Gauting, Gauting, Not set
Lungenfachklinik Immenhausen - Pneumologische Lehrklinik der Universitaet Goettingen, Immenhausen, Not set
MVZ for oncology and hematology Rhein-Kreis Neuss GmbH, Neuss, Not set
Praxiskooperation Bonn-Euskirchen-Rheinbach-Wesseling, Wesseling, Not set
Azienda Ospedaliera San Giuseppe Moscati, Avellino, Not set
Centro di Riferimento Oncologico, Aviano, Not set
IRCCS Istituto Romagnolo per lo studio dei Tumori Dino Amadori (IRST), Meldola, Not set
Casa Di Cura Polispecialistica Dott Pederzoli, Peschiera del Garda, Not set
Fondazione Policlinico Universitario Campus Bio-Medico, Roma, Not set
Fondazione Ospedale Isola Tiberina - Gemelli Isola, Rome, Not set
Chungbuk National University Hospital, Cheongju-si, Not set
Chungnam National University Hospital (CNUH), Daejeon, Not set
National Cancer Center, Goyang-si, Not set
Gachon University Gil Medical Center, Incheon, Not set
Gyeongsang National University Hospital (GNUH), Jinju-si, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
Asan Medical Center (AMC), Seoul, Not set
Samsung Medical Center, Seoul, Not set
Korea University Guro Hospital, Seoul, Not set
The Catholic University Of Korea, St. Vincent's Hospital, Suwon-si, Not set
Ajou University Hospital, Suwon-si, Not set
NZOZ Medpolonia Sp. Z o.o., Poznan, Not set
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu, Przemyśl, Not set
Instytut MSF Sp. z o.o., Łódź, Not set
Cardiomed, Cluj-Napoca, Not set
S.C. Medisprof S.R.L, Oncologie medicala, Cluj-Napoca, Not set
Radiotherapy Center Cluj, Cluj, Not set
Onco Clinic Consult SA, Craiova, Not set
Centrul de Oncologie Sf. Nectarie S.R.L (Sf Nectarie Oncology Center), Craiova, Not set
Ovidius Clinical Hospital, Ovidiu, Not set
Oncomed, Timisoara, Not set
Hospital Universitario Nuestra Senora De Valme, Sevilla, Not set
Hospital Universitario Virgen del Rocio, Seville, Not set
Adana City Training and Research Hospital, Adana, Not set
Gulhane Training and Research Hospital, Ankara, Not set
Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Not set
Hacettepe University Medicine Faculty, Ankara, Not set
Memorial Ankara Hospital, Ankara, Not set
Liv Hospital Ankara, Ankara, Not set
Ankara Bilkent City Hospital, Ankara, Not set
Akdeniz University Hospital, Antalya, Not set
Gaziantep Sanko University Medical Faculty, Gaziantep, Not set
Bezmialem Foundation University Medical Faculty, Istanbul, Not set
Yeditepe University Kosuyolu Hospital, Istanbul, Not set
Medical Point Izmir Hospital, İzmir, Not set
Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Kadıköy, Not set
Kocaeli Universitesi Tip Fakultesi, Kocaeli, Not set
Medical Park Florya Hospital, Kucukcekmece, Not set
Sakarya University - Faculty of Medicine, Sakarya, Not set
Ondokuz Mayis University Health Practice and Research Hospital, Samsun, Not set
Acibadem Adana Hospital, Seyhan, Not set
Medical Park Seyhan Hospital, Seyhan, Not set
Gazi University Faculty of Medicine, Yenimahalle, Not set
Koc Universitesi Hastanesi (Koc University Hospital), Zeytinburnu, Not set
Royal Sussex County Hospital - University Hospitals Sussex NHS Foundation Trust, Brighton, Not set
Velindre NHS Trust, Velindre Cancer Centre, Cardiff, Not set
Hull University Teaching Hospitals NHS Trust, Cottingham, Not set
University College Hospital, London, Not set
The Christie NHS Foundation Trust, Manchester, Not set
Cancer And Haematology Centre-The Churchill Hospital-Oxford University Hospitals, Oxford, Not set
Royal Preston Hospital - Lancashire Teaching Hospitals NHS Foundation Trust, Preston, Not set
Southampton General Hospital, Southampton, Not set
New Cross Hospital, Wolverhampton, Not set
Conditions: Non-small Cell Lung Cancer
Study of Pembrolizumab With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib in Stage III Non-Small Cell Lung Cancer (NSCLC) (MK-7339-012/KEYLYNK-012)
Active Not Recruiting
The purpose of this study is to assess the efficacy and safety of pembrolizumab in combination with concurrent chemoradiation therapy followed by either pembrolizumab with olaparib placebo (Arm 1) or with olaparib (Arm 2) compared to concurrent chemoradiation therapy followed by durvalumab (Arm 3) in participants with unresectable, locally advanced NSCLC. Arms 1 and 2 will be studied in a double-blind design and Arm 3 will be open-label. The primary hypotheses are:
1. Pembrolizumab with concurr... Read More
The purpose of this study is to assess the efficacy and safety of pembrolizumab in combination with concurrent chemoradiation therapy followed by either pembrolizumab with olaparib placebo (Arm 1) or with olaparib (Arm 2) compared to concurrent chemoradiation therapy followed by durvalumab (Arm 3) in participants with unresectable, locally advanced NSCLC. Arms 1 and 2 will be studied in a double-blind design and Arm 3 will be open-label. The primary hypotheses are:
1. Pembrolizumab with concurrent chemoradiation therapy followed by pembrolizumab with olaparib is superior to concurrent chemoradiation therapy followed by durvalumab with respect to progression-free survival (PFS) and overall survival (OS)
2. Pembrolizumab with concurrent chemoradiation therapy followed by pembrolizumab is superior to concurrent chemoradiation therapy followed by durvalumab with respect to PFS and OS Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/13/2025
Locations: University of South Alabama, Mitchell Cancer Institute ( Site 0003), Mobile, Alabama +204 locations
University of South Alabama, Mitchell Cancer Institute ( Site 0003), Mobile, Alabama
St. Bernards Medical Center ( Site 0089), Jonesboro, Arkansas
St Joseph Heritage Healthcare-Oncology ( Site 0088), Fullerton, California
Long Beach Memorial Medical Center ( Site 0006), Long Beach, California
UCLA Hematology/Oncology - Santa Monica ( Site 0013), Los Angeles, California
St. Joseph Heritage Healthcare Local Lab ( Site 0011), Santa Rosa, California
Torrance Memorial Physician Network / Cancer Center ( Site 0093), Torrance, California
Memorial Regional Hospital-Memorial Cancer Institute ( Site 0095), Hollywood, Florida
Miami VA Healthcare System ( Site 0024), Miami, Florida
Mid Florida Hematology and Oncology Center ( Site 0022), Orange City, Florida
Orlando Health, UF Health Cancer Center Inc ( Site 0092), Orlando, Florida
Fort Wayne Medical Oncology and Hematology ( Site 0094), Fort Wayne, Indiana
Parkview Research Center ( Site 0032), Fort Wayne, Indiana
Franciscan Health Lafayette East ( Site 0031), Lafayette, Indiana
University of Kentucky ( Site 0096), Lexington, Kentucky
Norton Brownsboro Hospital-Norton Cancer Institute - Brownsboro ( Site 0035), Louisville, Kentucky
Pikeville Medical Center ( Site 0036), Pikeville, Kentucky
Massachusetts General Hospital ( Site 0038), Boston, Massachusetts
Henry Ford Hospital ( Site 0045), Detroit, Michigan
VA St. Louis Health Care System ( Site 0047), Saint Louis, Missouri
Washington University Siteman Cancer Center ( Site 0046), Saint Louis, Missouri
CHI Health St. Francis ( Site 0053), Grand Island, Nebraska
Rutgers Cancer Institute of New Jersey ( Site 0054), New Brunswick, New Jersey
Valley Health Systems - Ridgewood Campus ( Site 0056), Paramus, New Jersey
Montefiore Einstein Center ( Site 0083), Bronx, New York
Novant Health Presbyterian ( Site 0081), Charlotte, North Carolina
Duke University Medical Center ( Site 0050), Durham, North Carolina
Piedmont Hematology-Oncology Associates ( Site 0080), Winston-Salem, North Carolina
The Lindner Center for Research and Education at The Christ Hospital ( Site 0060), Cincinnati, Ohio
Fox Chase Cancer Center ( Site 0063), Philadelphia, Pennsylvania
Sanford Cancer Center Oncology Clinic ( Site 0066), Sioux Falls, South Dakota
Veterans Affairs Puget Sound Health Care System [Seattle, WA] ( Site 0075), Seattle, Washington
Cancer Care Northwest ( Site 0074), Spokane Valley, Washington
Clinica Adventista Belgrano-Oncology ( Site 4002), Caba., Buenos Aires
Instituto Médico Río Cuarto ( Site 4003), Rio Cuarto., Cordoba
Queen Elizabeth II Health Sciences Centre ( Site 0100), Halifax, Nova Scotia
Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0102), Montreal, Quebec
CIUSSS Ouest de l Ile - St-Mary s Hospital ( Site 0108), Montreal, Quebec
McGill University Health Center - Research Institute ( Site 0114), Montreal, Quebec
Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0110), Quebec, Not set
Centro Investigación del Cáncer James Lind ( Site 0202), Temuco, Araucania
OrlandiOncologia ( Site 0201), Providencia, Region M. De Santiago
Bradfordhill ( Site 0200), Santiago, Region M. De Santiago
Oncocentro ( Site 0203), Vina del Mar, Valparaiso
Bradford Hill Norte ( Site 0204), Antofagasta, Not set
Peking Union Medical College Hospital ( Site 3201), Beijing, Beijing
Cancer Hospital Chinese Academy of Medical Sciences ( Site 3213), Beijing, Beijing
Beijing Cancer Hospital ( Site 3212), Beijing, Beijing
Beijing Cancer Hospital ( Site 3224), Beijing, Beijing
Daping Hospital,Third Military Medical University ( Site 3235), Chongqing, Chongqing
Fujian Provincial Cancer Hospital ( Site 3226), Fuzhou, Fujian
The First Affiliated Hospital of Xiamen University ( Site 3219), Xiamen, Fujian
Peking University Shenzhen Hospital ( Site 3216), Shenzhen, Guangdong
Cancer Hospital Chinese Academy Of Medical Sciences. Shenzhen Center ( Site 3200), Shenzhen, Guangdong
Henan Cancer Hospital ( Site 3205), Zhengzhou, Henan
Wuhan Union Hospital Cancer Center ( Site 3222), Wuhan, Hubei
Hubei Cancer Hospital ( Site 3218), Wuhan, Hubei
Xiangya Hospital of Central South University ( Site 3637), Changsha, Hunan
Second Xiangya Hospital of Central-South University ( Site 3227), Changsha, Hunan
Hunan Cancer Hospital ( Site 3225), Changsha, Hunan
Hunan Cancer Hospital ( Site 3238), Changsha, Hunan
Jiangsu Cancer Hospital ( Site 3234), Nanjing, Jiangsu
The Second Affiliated Hospital of Nanchang University ( Site 3206), Nanchang, Jiangxi
Jilin Cancer Hospital ( Site 3230), Changchun, Jilin
Shanghai Chest Hospital ( Site 3207), Shangai, Shanghai
Zhongshan Hospital Fudan University ( Site 3220), Shanghai, Shanghai
Shanghai Pulmonary Hospital ( Site 3203), Shanghai, Shanghai
West China Hospital of Sichuan University ( Site 3202), Chengdu, Sichuan
Tianjin Medical University Cancer Institute & Hospital ( Site 3204), Tianjin, Tianjin
The 1st Affil Hosp of College of Medicine, Zhejiang Univ ( Site 3232), Hangzhou, Zhejiang
Masarykuv onkologicky ustav ( Site 2206), Brno, Brno-mesto
Fakultni nemocnice Ostrava ( Site 2201), Ostrava, Ostrava Mesto
Fakultni nemocnice Kralovske Vinohrady-Radioterapeuticka a onkologicka klinika ( Site 2200), PRague, Praha 10
Fakultni nemocnice v Motole ( Site 2210), Praha, Praha 5
Nemocnice Na Plesi s.r.o. ( Site 2202), Nova Ves pod Plesi, Pribram
Krajska nemocnice Liberec, a.s. ( Site 2209), Liberec, Not set
Vseobecna fakultni nemocnice v Praze ( Site 2208), Praha 2, Not set
Nemocnice Na Bulovce ( Site 2205), Praha 8, Not set
North Estonia Medical Centre Foundation ( Site 1601), Tallin, Harjumaa
Tartu University Hospital ( Site 1600), Tartu, Tartumaa
Clinique Clairval ( Site 0802), Marseille, Bouches-du-Rhone
C.H.R.U. de Brest - Hopital Cavale Blanche ( Site 0806), Brest, Bretagne
Centre Hospitalier Annecy Genevois ( Site 0811), Epagny Metz Tessy, Haute-Savoie
Clinique Teissier Groupe ( Site 0808), Valenciennes, Nord
Hopital Avicenne ( Site 0803), Bobigny, Seine-Saint-Denis
Clinique de l'Europe-Service de pneumologie ( Site 0816), Amiens, Somme
H.I.A. Sainte-Anne ( Site 0815), Toulon, Var
CHD Vendee ( Site 0807), La Roche sur Yon, Vendee
Universitätsmedizin Göttingen - Georg-August-Universität ( Site 0917), Göttingen, Niedersachsen
Johannes Wesling Klinikum Minden ( Site 0908), Minden, Nordrhein-Westfalen
GEHO Muenster ( Site 0910), Muenster, Nordrhein-Westfalen
Johanna Etienne Hospital-Klinik für Onkologie ( Site 0916), Neuss, Nordrhein-Westfalen
LungenClinic Grosshansdorf GmbH ( Site 0901), Grosshansdorf, Schleswig-Holstein
Zentralklinik Bad Berka GmbH ( Site 0905), Bad Berka, Thuringen
Universitaetsklinikum Jena ( Site 0911), Jena, Thuringen
Charite-Universitaetsmedizin Berlin Campus Virchow-Klinikum ( Site 0900), Berlin, Not set
Katholisches Marienkrankenhaus gGmbH ( Site 0902), Hamburg, Not set
Bacs-Kiskun Megyei Korhaz-Onkoradiologiai Kozpont ( Site 2302), Kecskemét, Bacs-Kiskun
Bekes Megyei Kozponti Korhaz - Pandy Kalman Tagkorhaza ( Site 2303), Gyula, Bekes
Petz Aladar Megyei Oktato Korhaz ( Site 2306), Gyor, Gyor-Moson-Sopron
Orszagos Koranyi Pulmonologiai Intezet ( Site 2305), Budapest, Not set
Országos Korányi Pulmonológiai Intézet-VI. Tüdöbelosztály és Bronchológia ( Site 2309), Budapest, Not set
Azienda Ospedaliera Umberto I- Torrette ( Site 1009), Torrette, Ancona
Policlinico Agostino Gemelli ( Site 1002), Roma, Lazio
Istituto Clinico Humanitas Research Hospital ( Site 1000), Rozzano, Lombardia
Azienda Ospedaliero Universitaria Careggi ( Site 1001), Firenze, Not set
Azienda Ospedaliera Vito Fazzi ( Site 1003), Lecce, Not set
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 1008), Milano, Not set
Policlinico di Modena ( Site 1007), Modena, Not set
A.O.U. Santa Maria della Misericordia di Udine ( Site 1004), Udine, Not set
Kurume University Hospital ( Site 3112), Kurume, Fukuoka
Kobe Minimally Invasive Cancer Center ( Site 3100), Kobe, Hyogo
Kanagawa Cancer Center ( Site 3101), Yokohama, Kanagawa
Kansai Medical University Hospital ( Site 3103), Hirakata, Osaka
Osaka Medical and Pharmaceutical University Hospital ( Site 3110), Takatsuki, Osaka
National Hospital Organization Kyushu Cancer Center ( Site 3104), Fukuoka, Not set
Niigata Cancer Center Hospital ( Site 3109), Niigata, Not set
Osaka International Cancer Institute ( Site 3106), Osaka, Not set
Juntendo University Hospital ( Site 3111), Tokyo, Not set
Tokyo Metropolitan Komagome Hospital ( Site 3108), Tokyo, Not set
Cancer Institute Hospital of JFCR ( Site 3107), Tokyo, Not set
Showa Medical University Hospital ( Site 3105), Tokyo, Not set
Chungbuk National University Hospital ( Site 2802), Cheongju-si, Chungbuk
National Cancer Center ( Site 2800), Goyang-si, Kyonggi-do
Seoul National University Bundang Hospital ( Site 2801), Seongnam-si, Kyonggi-do
Ajou University Hospital ( Site 2803), Suwon-si, Kyonggi-do
The Catholic University of Korea St. Vincent s Hospital ( Site 2805), Suwonsi, Kyonggi-do
Gyeongsang National University Hospital ( Site 2804), Jinju-si, Kyongsangnam-do
Keimyung University Dongsan Hospital CRC room 1 ( Site 2807), Daegu, Taegu-Kwangyokshi
Kangbuk Samsung Hospital ( Site 2806), Seoul, Not set
Severance Hospital Yonsei University Health System ( Site 2808), Seoul, Not set
Pauls Stradins Clinical University Hospital ( Site 1501), Riga, Not set
Riga East Clinical University Hospital ( Site 1500), Riga, Not set
Hospital of Lithuanian University of Health Sciences Kauno klinikos-Pulmonology ( Site 4201), Kaunas, Kauno Apskritis
National Cancer Institute-Department of Thoracic Surgery and Oncology ( Site 4200), Vilnius, Vilniaus Miestas
Hospital Civil de Guadalajara Fray Antonio Alcalde ( Site 0500), Guadalajara, Jalisco
Hospital Universitario "Dr. Jose Eleuterio Gonzalez" ( Site 0508), Monterrey, Nuevo Leon
CLIMERS Clinical Medical Research ( Site 0506), Orizaba, Veracruz
Instituto Nacional de Cancerologia ( Site 0502), Tlalpan, Not set
Akershus Universitetssykehus HF ( Site 1106), Lorenskog, Akershus
Vestre Viken HF Drammen Sykehus ( Site 1101), Drammen, Buskerud
Sykehuset Oestfold ( Site 1107), Gralum, Ostfold
Helse Stavanger HF Stavanger Universitetssjukehus ( Site 1103), Stavanger, Rogaland
Oslo Universitetssykehus HF. Ulleval ( Site 1100), Oslo, Not set
Hospital Nacional Carlos Alberto Seguin Escobedo ESSALUD ( Site 0604), Arequipa, Ariqipa
Detecta Clínica ( Site 0607), Surquillo, Muni Metro De Lima
IPOR Instituto Peruano de Oncología & Radioterapia ( Site 0606), Lima, Not set
Oncosalud ( Site 0605), Lima, Not set
Clinica San Gabriel ( Site 0601), Lima, Not set
Hospital Nacional Cayetano Heredia ( Site 0602), Lima, Not set
Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 2404), Siedlce, Mazowieckie
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie ( Site 2402), Warszawa, Mazowieckie
Szpital Morski im. PCK. Szpitale Pomorskie Sp. Z o.o ( Site 2400), Gdynia, Pomorskie
SPZOZ MSWIA z Warminsko-Mazurskim Centrum Onkologii w Olsztynie ( Site 2401), Olsztyn, Warminsko-mazurskie
MEMORIAL HEALTHCARE INTERNATIONAL S.R.L. ( Site 2500), Bucharest, Bucuresti
Spitalul Universitar de Urgenta Bucuresti ( Site 2508), Bucharest, Bucuresti
Gral Medical SRL-Medical Oncology ( Site 2511), București, Bucuresti
Institutul Oncologic Prof.Dr. Ion Chiricuta Cluj-Napoca ( Site 2506), Cluj Napoca, Cluj
S.C. Radiotherapy Center Cluj S.R.L ( Site 2503), Comuna Floresti, Cluj
Centrul de Oncologie Sfantul Nectarie-Medical ( Site 2510), Craiova, Dolj
Radiology Therapeutic Center-Oncology ( Site 2502), Otopeni, Ilfov
Policlinica Oncomed SRL ( Site 2504), Timisoara, Timis
S C Oncocenter Oncologie Clinica S R L-Medical Oncology ( Site 2509), Timișoara, Timis
Spitalul Clinic Judetean De Urgenta Constanta ( Site 2501), Constanta, Not set
Institutul Regional de Oncologie Iasi ( Site 2505), Iasi, Not set
Chelyabinsk Regional Clinical Oncological Dispensary ( Site 1913), Chelyabinsk, Chelyabinskaya Oblast
MSROI named after P.A. Hertsen branch of FSBI NMRC Radiology ( Site 1903), Moscow, Moskva
Nizhniy Novgorod Region Oncology Dispensary ( Site 1914), Nizhniy Novgorod, Nizhegorodskaya Oblast
Scientific Research Oncology Institute n.a. N.N.Petrov ( Site 1905), Saint-Petersburg, Sankt-Peterburg
Medical institute named after Berezin Sergey ( Site 1906), St. Petersburg, Sankt-Peterburg
Sverdlovsk Regional Oncology Hospital ( Site 1909), Ekaterinburg, Sverdlovskaya Oblast
Republican Clinical Oncology Dispensary of Tatarstan MoH named after professor M.Z. Sigal ( Site 1911), Kazan, Tatarstan, Respublika
Yaroslavl Regional SBIH Clinical Oncology Hospital ( Site 1910), Yaroslavl, Yaroslavskaya Oblast
Hospital Universitario Puerta de Hierro (Majadahonda) ( Site 1202), Majadahonda, Madrid
Hospital Universitario Quiron Madrid ( Site 1200), Pozuelo de Alarcon, Madrid
H.R.U Malaga - Hospital General ( Site 1206), Málaga, Malaga
H.U. Vall de Hebron ( Site 1201), Barcelona, Not set
Hospital Clinic de Barcelona ( Site 1204), Barcelona, Not set
Hospital Universitario Virgen Macarena ( Site 1205), Sevilla, Not set
Hospital Universitario La Fe ( Site 1203), Valencia, Not set
Chulalongkorn University ( Site 3003), Bangkok, Krung Thep Maha Nakhon
Ramathibodi Hospital. ( Site 3000), Bangkok, Krung Thep Maha Nakhon
Chiang Mai University Maharaj Nakorn Chiang Mai Hospital ( Site 3001), Chiang Mai, Not set
Srinagarind Hospital. Khon Kaen University ( Site 3002), Khon Kaen, Not set
Ankara Bilkent Sehir Hastanesi ( Site 2002), Ankara, Adana
Memorial Ankara Hastanesi ( Site 2006), Ankara, Not set
Istanbul Uni. Cerrahpasa Tip Fakultesi ( Site 2000), Istanbul, Not set
Medipol Universite Hastanesi ( Site 2003), Istanbul, Not set
Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi-oncology ( Site 2001), Istanbul, Not set
Ege University Medical Faculty ( Site 2005), Izmir, Not set
Medical center Medikal Plaza of Ecodnipro LLC ( Site 2107), Dnipro, Dnipropetrovska Oblast
SOGrigoriev Inst for Med Radiolgy and Oncology of NAMS of Ukraine-Clinical oncology and hematology ( Site 2110), Kharkiv, Kharkivska Oblast
Communal nonprofit enterprise "Kherson Regional Oncology Dispensary" of Kherson Regional Council ( Site 2109), Antonivka Village, Khersonska Oblast
LLC Ukrainian Center of Tomotherapy ( Site 2105), Kropyvnytskyi, Kirovohradska Oblast
Medical Center of Yuriy Spizhenko LLC.-Clinical Trial ( Site 2104), Kapitanivka Village, Kyivska Oblast
SNPE National Cancer Institute ( Site 2101), Kyiv, Kyivska Oblast
Medical Center Verum ( Site 2106), Kyiv, Kyivska Oblast
Kyiv City Clinical Oncology Center ( Site 2100), Kyiv, Not set
Weston Park Hospital ( Site 1406), Sheffield, Derbyshire
University College Hospital NHS Foundation Trust ( Site 1403), London-Camden, London, City Of
Guys and St Thomas NHS Foundation Trust ( Site 1410), London, London, City Of
Royal Marsden Hospital (Sutton) ( Site 1407), London, Surrey
Southampton General Hospital ( Site 1400), Southampton, Worcestershire
Leeds Teaching Hospitals NHS Trust ( Site 1401), Leeds, Not set
Christie NHS Foundation Trust ( Site 1409), Manchester, Not set
Conditions: Lung Neoplasms, Carcinoma, Non-Small-Cell Lung
AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2
Recruiting
The purpose of this study is to measure the efficacy and safety of AZD0901 compared to Investigator's choice of therapy as 2L+ treatment for participants with advanced or metastatic gastric or GEJ adenocarcinoma expressing CLDN18.2.
The purpose of this study is to measure the efficacy and safety of AZD0901 compared to Investigator's choice of therapy as 2L+ treatment for participants with advanced or metastatic gastric or GEJ adenocarcinoma expressing CLDN18.2. Read Less
Gender:
ALL
Ages:
Between 18 years and 130 years
Trial Updated:
08/12/2025
Locations: Research Site, Birmingham, Alabama +186 locations
Research Site, Birmingham, Alabama
Research Site, Mobile, Alabama
Research Site, Tucson, Arizona
Research Site, Duarte, California
Research Site, Fullerton, California
Research Site, Irvine, California
Research Site, Los Angeles, California
Research Site, Los Angeles, California
Research Site, Newport Beach, California
Research Site, Santa Rosa, California
Research Site, Washington, District of Columbia
Research Site, Fleming Island, Florida
Research Site, Hollywood, Florida
Research Site, Orlando, Florida
Research Site, Atlanta, Georgia
Research Site, Marietta, Georgia
Research Site, Honolulu, Hawaii
Research Site, Boise, Idaho
Research Site, Lexington, Kentucky
Research Site, Baltimore, Maryland
Research Site, Boston, Massachusetts
Research Site, Ann Arbor, Michigan
Research Site, Ann Arbor, Michigan
Research Site, Kansas City, Missouri
Research Site, Saint Louis, Missouri
Research Site, Saint Louis, Missouri
Research Site, Mineola, New York
Research Site, New York, New York
Research Site, New York, New York
Research Site, New York, New York
Research Site, Cincinnati, Ohio
Research Site, Portland, Oregon
Research Site, Philadelphia, Pennsylvania
Research Site, York, Pennsylvania
Research Site, Charlottesville, Virginia
Research Site, Fredericksburg, Virginia
Research Site, Olympia, Washington
Research Site, Seattle, Washington
Research Site, Porto Alegre, Not set
Research Site, Ribeirao Preto, Not set
Research Site, São Paulo, Not set
Research Site, Vitória, Not set
Research Site, Calgary, Alberta
Research Site, Barrie, Ontario
Research Site, London, Ontario
Research Site, North York, Ontario
Research Site, Ottawa, Ontario
Research Site, Toronto, Ontario
Research Site, Montreal, Quebec
Research Site, Montreal, Quebec
Research Site, Beijing, Not set
Research Site, Changchun, Not set
Research Site, Changsha, Not set
Research Site, Chengdu, Not set
Research Site, Chengdu, Not set
Research Site, Fuzhou, Not set
Research Site, Fuzhou, Not set
Research Site, Guangzhou, Not set
Research Site, Guangzhou, Not set
Research Site, Guangzhou, Not set
Research Site, Guangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Harbin, Not set
Research Site, Hefei, Not set
Research Site, Hefei, Not set
Research Site, Hefei, Not set
Research Site, Jinan, Not set
Research Site, Jining, Not set
Research Site, Lanzhou, Not set
Research Site, Lishui, Not set
Research Site, Luoyang, Not set
Research Site, Nanjing, Not set
Research Site, Nanjing, Not set
Research Site, Qingdao, Not set
Research Site, Shanghai, Not set
Research Site, Shanghai, Not set
Research Site, Shanghai, Not set
Research Site, Shenyang, Not set
Research Site, Shijiazhuang, Not set
Research Site, Suzhou, Not set
Research Site, Tianjin, Not set
Research Site, Urumqi, Not set
Research Site, Wuhan, Not set
Research Site, Wuhan, Not set
Research Site, Xi'an, Not set
Research Site, Yinchuan, Not set
Research Site, Zhengzhou, Not set
Research Site, Besançon Cedex, Not set
Research Site, Brest, Not set
Research Site, Lille, Not set
Research Site, Lyon, Not set
Research Site, Nantes, Not set
Research Site, PARIS Cedex 12, Not set
Research Site, Poitiers, Not set
Research Site, Berlin, Not set
Research Site, Berlin, Not set
Research Site, Dresden, Not set
Research Site, Dresden, Not set
Research Site, Essen, Not set
Research Site, Frankfurt, Not set
Research Site, Göttingen, Not set
Research Site, Hamburg, Not set
Research Site, Heidelberg, Not set
Research Site, Heilbronn, Not set
Research Site, Leipzig, Not set
Research Site, Mainz, Not set
Research Site, Marburg, Not set
Research Site, Moers, Not set
Research Site, München, Not set
Research Site, Hong Kong, Not set
Research Site, Hong Kong, Not set
Research Site, Ahmedabad, Not set
Research Site, Bengaluru, Not set
Research Site, Hyderabad, Not set
Research Site, Mumbai, Not set
Research Site, New Delhi, Not set
Research Site, Florence, Not set
Research Site, Milano, Not set
Research Site, Milan, Not set
Research Site, Modena, Not set
Research Site, Napoli, Not set
Research Site, Padova, Not set
Research Site, Pisa, Not set
Research Site, Vicenza, Not set
Research Site, Fukuoka-shi, Not set
Research Site, Kashiwa, Not set
Research Site, Koto-ku, Not set
Research Site, Nagoya-shi, Not set
Research Site, Ogaki-shi, Not set
Research Site, Osaka-shi, Not set
Research Site, Sunto-gun, Not set
Research Site, Tokyo, Not set
Research Site, Toyoake-shi, Not set
Research Site, Yokohama-shi, Not set
Research Site, Gyeonggi-do, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Bielsko-Biała, Not set
Research Site, Gdańsk, Not set
Research Site, Katowice, Not set
Research Site, Kraków, Not set
Research Site, Lublin, Not set
Research Site, Szczecin, Not set
Research Site, Słupsk, Not set
Research Site, Tomaszów Mazowiecki, Not set
Research Site, Warszawa, Not set
Research Site, Warszawa, Not set
Research Site, Barcelona, Not set
Research Site, Barcelona, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, Orense, Not set
Research Site, Santander, Not set
Research Site, Sevilla, Not set
Research Site, Bern, Not set
Research Site, Genève 14, Not set
Research Site, Lausanne, Not set
Research Site, Zürich, Not set
Research Site, Kaohsiung, Not set
Research Site, Kaohsiung, Not set
Research Site, Taichung, Not set
Research Site, Tainan, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taoyuan, Not set
Research Site, Bangkok, Not set
Research Site, Dusit, Not set
Research Site, Hat Yai, Not set
Research Site, Khon-Kaen, Not set
Research Site, Ankara, Not set
Research Site, Diyarbakir, Not set
Research Site, Erzurum, Not set
Research Site, İstanbul, Not set
Research Site, Cambridge, Not set
Research Site, London, Not set
Research Site, London, Not set
Research Site, Manchester, Not set
Research Site, Oxford, Not set
Research Site, Taunton, Not set
Research Site, Hanoi, Not set
Research Site, Ho Chi Minh City, Not set
Research Site, Ho Chi Minh, Not set
Research Site, Vinh, Not set
Conditions: Gastric Cancer, Gastroesophageal Junction Cancer
Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer
Active Not Recruiting
This phase II/III trial studies how well trametinib works and compares it to standard treatment with either letrozole, tamoxifen, paclitaxel, pegylated liposomal doxorubicin, or topotecan in treating patients with low-grade ovarian cancer or peritoneal cavity cancer that has come back (recurrent), become worse (progressive), or spread to other parts of the body. Trametinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known whether trame... Read More
This phase II/III trial studies how well trametinib works and compares it to standard treatment with either letrozole, tamoxifen, paclitaxel, pegylated liposomal doxorubicin, or topotecan in treating patients with low-grade ovarian cancer or peritoneal cavity cancer that has come back (recurrent), become worse (progressive), or spread to other parts of the body. Trametinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known whether trametinib is more effective than standard therapy in treating patients with ovarian or peritoneal cavity cancer. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
08/12/2025
Locations: Tennessee Valley Gynecologic Oncology, Huntsville, Alabama +500 locations
Tennessee Valley Gynecologic Oncology, Huntsville, Alabama
Anchorage Associates in Radiation Medicine, Anchorage, Alaska
Anchorage Radiation Therapy Center, Anchorage, Alaska
Alaska Breast Care and Surgery LLC, Anchorage, Alaska
Alaska Oncology and Hematology LLC, Anchorage, Alaska
Alaska Women's Cancer Care, Anchorage, Alaska
Anchorage Oncology Centre, Anchorage, Alaska
Katmai Oncology Group, Anchorage, Alaska
Providence Alaska Medical Center, Anchorage, Alaska
Fairbanks Memorial Hospital, Fairbanks, Alaska
Banner University Medical Center - Tucson, Tucson, Arizona
University of Arizona Cancer Center-North Campus, Tucson, Arizona
CHI Saint Vincent Cancer Center Hot Springs, Hot Springs, Arkansas
Sutter Auburn Faith Hospital, Auburn, California
Sutter Cancer Centers Radiation Oncology Services-Auburn, Auburn, California
Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California
Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California
Mills-Peninsula Medical Center, Burlingame, California
Sutter Cancer Centers Radiation Oncology Services-Cameron Park, Cameron Park, California
Eden Hospital Medical Center, Castro Valley, California
Community Cancer Institute, Clovis, California
University Oncology Associates, Clovis, California
Sutter Davis Hospital, Davis, California
Palo Alto Medical Foundation-Fremont, Fremont, California
Memorial Medical Center, Modesto, California
Palo Alto Medical Foundation-Camino Division, Mountain View, California
Palo Alto Medical Foundation-Gynecologic Oncology, Mountain View, California
Sutter Cancer Research Consortium, Novato, California
Palo Alto Medical Foundation Health Care, Palo Alto, California
Stanford Cancer Institute Palo Alto, Palo Alto, California
Sutter Cancer Centers Radiation Oncology Services-Roseville, Roseville, California
Sutter Roseville Medical Center, Roseville, California
Sutter Medical Center Sacramento, Sacramento, California
California Pacific Medical Center-Pacific Campus, San Francisco, California
UCSF Medical Center-Mission Bay, San Francisco, California
Stanford Cancer Center South Bay, San Jose, California
Palo Alto Medical Foundation-Santa Cruz, Santa Cruz, California
Sutter Pacific Medical Foundation, Santa Rosa, California
Palo Alto Medical Foundation-Sunnyvale, Sunnyvale, California
Sutter Solano Medical Center/Cancer Center, Vallejo, California
Rocky Mountain Cancer Centers-Aurora, Aurora, Colorado
The Medical Center of Aurora, Aurora, Colorado
Boulder Community Foothills Hospital, Boulder, Colorado
Rocky Mountain Cancer Centers-Boulder, Boulder, Colorado
Penrose-Saint Francis Healthcare, Colorado Springs, Colorado
Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado
Denver Health Medical Center, Denver, Colorado
National Jewish Health-Main Campus, Denver, Colorado
The Women's Imaging Center, Denver, Colorado
AdventHealth Porter, Denver, Colorado
Colorado Blood Cancer Institute, Denver, Colorado
Presbyterian - Saint Lukes Medical Center - Health One, Denver, Colorado
Rocky Mountain Cancer Centers-Midtown, Denver, Colorado
Saint Joseph Hospital - Cancer Centers of Colorado, Denver, Colorado
Rocky Mountain Cancer Centers-Rose, Denver, Colorado
Rose Medical Center, Denver, Colorado
Western States Cancer Research NCORP, Denver, Colorado
CommonSpirit Cancer Center Mercy, Durango, Colorado
Mercy Medical Center, Durango, Colorado
Mountain Blue Cancer Care Center - Swedish, Englewood, Colorado
Swedish Medical Center, Englewood, Colorado
Mountain Blue Cancer Care Center, Golden, Colorado
National Jewish Health-Western Hematology Oncology, Golden, Colorado
Banner North Colorado Medical Center, Greeley, Colorado
Rocky Mountain Cancer Centers-Greenwood Village, Greenwood Village, Colorado
Rocky Mountain Cancer Centers-Lakewood, Lakewood, Colorado
Saint Anthony Hospital, Lakewood, Colorado
Rocky Mountain Cancer Centers-Littleton, Littleton, Colorado
AdventHealth Littleton, Littleton, Colorado
Rocky Mountain Cancer Centers-Sky Ridge, Lone Tree, Colorado
Sky Ridge Medical Center, Lone Tree, Colorado
Longmont United Hospital, Longmont, Colorado
Rocky Mountain Cancer Centers-Longmont, Longmont, Colorado
Banner McKee Medical Center, Loveland, Colorado
AdventHealth Parker, Parker, Colorado
Rocky Mountain Cancer Centers-Parker, Parker, Colorado
Saint Mary Corwin Medical Center, Pueblo, Colorado
Rocky Mountain Cancer Centers - Pueblo, Pueblo, Colorado
National Jewish Health-Northern Hematology Oncology, Thornton, Colorado
Rocky Mountain Cancer Centers-Thornton, Thornton, Colorado
Intermountain Health Lutheran Hospital, Wheat Ridge, Colorado
Hartford Hospital, Hartford, Connecticut
Smilow Cancer Hospital Care Center at Saint Francis, Hartford, Connecticut
The Hospital of Central Connecticut, New Britain, Connecticut
Sibley Memorial Hospital, Washington, District of Columbia
UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables, Florida
UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida
Jackson Memorial Hospital-Holtz Children's Hospital, Miami, Florida
University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida
UM Sylvester Comprehensive Cancer Center at Plantation, Plantation, Florida
Northside Hospital, Atlanta, Georgia
John B Amos Cancer Center, Columbus, Georgia
Northside Hospital-Forsyth, Cumming, Georgia
Northeast Georgia Medical Center-Gainesville, Gainesville, Georgia
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Savannah, Georgia
Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho
Saint Luke's Cancer Institute - Boise, Boise, Idaho
Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho
Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho
Walter Knox Memorial Hospital, Emmett, Idaho
Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho
Idaho Urologic Institute-Meridian, Meridian, Idaho
Saint Luke's Cancer Institute - Meridian, Meridian, Idaho
Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho
Saint Luke's Cancer Institute - Nampa, Nampa, Idaho
Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho
Kootenai Clinic Cancer Services - Sandpoint, Sandpoint, Idaho
Saint Luke's Cancer Institute - Twin Falls, Twin Falls, Idaho
Rush-Copley Medical Center, Aurora, Illinois
Northwestern University, Chicago, Illinois
Swedish Covenant Hospital, Chicago, Illinois
Carle at The Riverfront, Danville, Illinois
Carle Physician Group-Effingham, Effingham, Illinois
NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois
Saint Francis Hospital, Evanston, Illinois
Northwestern Medicine Cancer Center Delnor, Geneva, Illinois
NorthShore University HealthSystem-Glenbrook Hospital, Glenview, Illinois
NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois
Sudarshan K Sharma MD Limited-Gynecologic Oncology, Hinsdale, Illinois
Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois
SSM Health Good Samaritan, Mount Vernon, Illinois
North Shore Medical Center, Skokie, Illinois
Carle Cancer Center, Urbana, Illinois
The Carle Foundation Hospital, Urbana, Illinois
Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois
Rush-Copley Healthcare Center, Yorkville, Illinois
Michiana Hematology Oncology PC-Crown Point, Crown Point, Indiana
Elkhart Clinic, Elkhart, Indiana
Michiana Hematology Oncology PC-Elkhart, Elkhart, Indiana
Elkhart General Hospital, Elkhart, Indiana
Deaconess Clinic Downtown, Evansville, Indiana
Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana
Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana
Community Howard Regional Health, Kokomo, Indiana
IU Health La Porte Hospital, La Porte, Indiana
Franciscan Saint Anthony Health-Michigan City, Michigan City, Indiana
Woodland Cancer Care Center, Michigan City, Indiana
Memorial Regional Cancer Center Day Road, Mishawaka, Indiana
Michiana Hematology Oncology PC-Mishawaka, Mishawaka, Indiana
Saint Joseph Regional Medical Center-Mishawaka, Mishawaka, Indiana
Chancellor Center for Oncology, Newburgh, Indiana
Michiana Hematology Oncology PC-Plymouth, Plymouth, Indiana
Memorial Hospital of South Bend, South Bend, Indiana
South Bend Clinic, South Bend, Indiana
Michiana Hematology Oncology PC-Westville, Westville, Indiana
Mercy Cancer Center-West Lakes, Clive, Iowa
UI Health Care Mission Cancer and Blood - West Des Moines Clinic, Clive, Iowa
Alegent Health Mercy Hospital, Council Bluffs, Iowa
Greater Regional Medical Center, Creston, Iowa
Iowa Methodist Medical Center, Des Moines, Iowa
UI Health Care Mission Cancer and Blood - Des Moines Clinic, Des Moines, Iowa
Broadlawns Medical Center, Des Moines, Iowa
Mercy Medical Center - Des Moines, Des Moines, Iowa
UI Health Care Mission Cancer and Blood - Laurel Clinic, Des Moines, Iowa
Iowa Lutheran Hospital, Des Moines, Iowa
Methodist West Hospital, West Des Moines, Iowa
Mercy Medical Center-West Lakes, West Des Moines, Iowa
Flaget Memorial Hospital, Bardstown, Kentucky
Commonwealth Cancer Center-Corbin, Corbin, Kentucky
Saint Joseph Radiation Oncology Resource Center, Lexington, Kentucky
Saint Joseph Hospital East, Lexington, Kentucky
Saint Joseph London, London, Kentucky
Jewish Hospital, Louisville, Kentucky
The James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky
Saints Mary and Elizabeth Hospital, Louisville, Kentucky
UofL Health Medical Center Northeast, Louisville, Kentucky
Jewish Hospital Medical Center South, Shepherdsville, Kentucky
Woman's Hospital, Baton Rouge, Louisiana
MaineHealth Maine Medical Center- Scarborough, Scarborough, Maine
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland
Walter Reed National Military Medical Center, Bethesda, Maryland
Baystate Medical Center, Springfield, Massachusetts
Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan
Bronson Battle Creek, Battle Creek, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan
Trinity Health Medical Center - Brighton, Brighton, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan
Trinity Health Medical Center - Canton, Canton, Michigan
Caro Cancer Center, Caro, Michigan
Chelsea Hospital, Chelsea, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan
Hematology Oncology Consultants-Clarkston, Clarkston, Michigan
Newland Medical Associates-Clarkston, Clarkston, Michigan
Corewell Health Dearborn Hospital, Dearborn, Michigan
Henry Ford Health Saint John Hospital, Detroit, Michigan
Henry Ford River District Hospital, East China Township, Michigan
Cancer Hematology Centers - Flint, Flint, Michigan
Genesee Hematology Oncology PC, Flint, Michigan
Genesys Hurley Cancer Institute, Flint, Michigan
Hurley Medical Center, Flint, Michigan
Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids, Michigan
Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan
Henry Ford Saint John Hospital - Academic, Grosse Pointe Woods, Michigan
Henry Ford Saint John Hospital - Breast, Grosse Pointe Woods, Michigan
Henry Ford Saint John Hospital - Van Elslander, Grosse Pointe Woods, Michigan
Allegiance Health, Jackson, Michigan
West Michigan Cancer Center, Kalamazoo, Michigan
Beacon Kalamazoo, Kalamazoo, Michigan
University of Michigan Health - Sparrow Lansing, Lansing, Michigan
Hope Cancer Clinic, Livonia, Michigan
Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan
Henry Ford Saint John Hospital - Macomb Medical, Macomb, Michigan
Henry Ford Warren Hospital - Breast Macomb, Macomb, Michigan
Saint Mary's Oncology/Hematology Associates of Marlette, Marlette, Michigan
Monroe Cancer Center, Monroe, Michigan
Trinity Health Muskegon Hospital, Muskegon, Michigan
Corewell Health Lakeland Hospitals - Niles Hospital, Niles, Michigan
Hope Cancer Center, Pontiac, Michigan
Michigan Healthcare Professionals Pontiac, Pontiac, Michigan
Newland Medical Associates-Pontiac, Pontiac, Michigan
Trinity Health Saint Joseph Mercy Oakland Hospital, Pontiac, Michigan
Lake Huron Medical Center, Port Huron, Michigan
Corewell Health Reed City Hospital, Reed City, Michigan
Henry Ford Rochester Hospital, Rochester Hills, Michigan
MyMichigan Medical Center Saginaw, Saginaw, Michigan
Oncology Hematology Associates of Saginaw Valley PC, Saginaw, Michigan
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center, Saint Joseph, Michigan
Corewell Health Lakeland Hospitals - Saint Joseph Hospital, Saint Joseph, Michigan
Bhadresh Nayak MD PC-Sterling Heights, Sterling Heights, Michigan
MyMichigan Medical Center Tawas, Tawas City, Michigan
Munson Medical Center, Traverse City, Michigan
Advanced Breast Care Center PLLC, Warren, Michigan
Henry Ford Health Warren Hospital, Warren, Michigan
Henry Ford Madison Heights Hospital - Breast, Warren, Michigan
Henry Ford Warren Hospital - GLCMS, Warren, Michigan
Macomb Hematology Oncology PC, Warren, Michigan
Saint Mary's Oncology/Hematology Associates of West Branch, West Branch, Michigan
University of Michigan Health - West, Wyoming, Michigan
Huron Gastroenterology PC, Ypsilanti, Michigan
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan
Sanford Joe Lueken Cancer Center, Bemidji, Minnesota
University of Mississippi Medical Center, Jackson, Mississippi
Central Care Cancer Center - Bolivar, Bolivar, Missouri
Cox Cancer Center Branson, Branson, Missouri
Freeman Health System, Joplin, Missouri
Mercy Hospital Joplin, Joplin, Missouri
Mercy Clinic-Rolla-Cancer and Hematology, Rolla, Missouri
Phelps Health Delbert Day Cancer Institute, Rolla, Missouri
Heartland Regional Medical Center, Saint Joseph, Missouri
Mercy Infusion Center - Chippewa, Saint Louis, Missouri
Barnes-Jewish Hospital, Saint Louis, Missouri
Washington University School of Medicine, Saint Louis, Missouri
Mercy Hospital Saint Louis, Saint Louis, Missouri
Mercy Hospital Springfield, Springfield, Missouri
CoxHealth South Hospital, Springfield, Missouri
Community Hospital of Anaconda, Anaconda, Montana
Billings Clinic Cancer Center, Billings, Montana
Saint Vincent Healthcare, Billings, Montana
Bozeman Health Deaconess Hospital, Bozeman, Montana
Saint James Community Hospital and Cancer Treatment Center, Butte, Montana
Benefis Sletten Cancer Institute, Great Falls, Montana
Great Falls Clinic, Great Falls, Montana
Saint Peter's Community Hospital, Helena, Montana
Logan Health Medical Center, Kalispell, Montana
Saint Patrick Hospital - Community Hospital, Missoula, Montana
Community Medical Center, Missoula, Montana
Nebraska Cancer Specialists/Oncology Hematology West PC, Grand Island, Nebraska
Fred and Pamela Buffett Cancer Center - Kearney, Kearney, Nebraska
CHI Health Good Samaritan, Kearney, Nebraska
Saint Elizabeth Regional Medical Center, Lincoln, Nebraska
Nebraska Methodist Hospital, Omaha, Nebraska
Alegent Health Immanuel Medical Center, Omaha, Nebraska
Hematology and Oncology Consultants PC, Omaha, Nebraska
Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska
Alegent Health Lakeside Hospital, Omaha, Nebraska
Creighton University Medical Center, Omaha, Nebraska
University of Nebraska Medical Center, Omaha, Nebraska
Midlands Community Hospital, Papillion, Nebraska
Women's Cancer Center of Nevada, Las Vegas, Nevada
Center of Hope at Renown Medical Center, Reno, Nevada
Renown Regional Medical Center, Reno, Nevada
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire
Cooper Hospital University Medical Center, Camden, New Jersey
Hackensack University Medical Center, Hackensack, New Jersey
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
Southwest Gynecologic Oncology Associates Inc, Albuquerque, New Mexico
University of New Mexico Cancer Center, Albuquerque, New Mexico
New Mexico Cancer Research Alliance, Albuquerque, New Mexico
Roswell Park Cancer Institute, Buffalo, New York
NYP/Weill Cornell Medical Center, New York, New York
University of Rochester, Rochester, New York
Dickstein Cancer Treatment Center, White Plains, New York
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Novant Health Presbyterian Medical Center, Charlotte, North Carolina
Oncology Specialists of Charlotte, Charlotte, North Carolina
Southern Oncology Specialists-Charlotte, Charlotte, North Carolina
Sampson Radiation Oncology, Clinton, North Carolina
Southeastern Medical Oncology Center-Clinton, Clinton, North Carolina
Duke University Medical Center, Durham, North Carolina
Southeastern Medical Oncology Center-Goldsboro, Goldsboro, North Carolina
Wayne Memorial Hospital, Goldsboro, North Carolina
Wayne Radiation Oncology, Goldsboro, North Carolina
Novant Health Cancer Institute - Huntersville, Huntersville, North Carolina
Southern Oncology Specialists-Huntersville, Huntersville, North Carolina
Onslow Memorial Hospital, Jacksonville, North Carolina
Southeastern Medical Oncology Center-Jacksonville, Jacksonville, North Carolina
Matthews Radiation Oncology Center, Matthews, North Carolina
Novant Health Cancer Institute - Matthews, Matthews, North Carolina
Novant Health Cancer Institute - Mooresville, Mooresville, North Carolina
Duke Women's Cancer Care Raleigh, Raleigh, North Carolina
Duke Cancer Center Raleigh, Raleigh, North Carolina
Sanford Bismarck Medical Center, Bismarck, North Dakota
Sanford Broadway Medical Center, Fargo, North Dakota
Sanford Roger Maris Cancer Center, Fargo, North Dakota
UHHS-Chagrin Highlands Medical Center, Beachwood, Ohio
Strecker Cancer Center-Belpre, Belpre, Ohio
Adena Regional Medical Center, Chillicothe, Ohio
University of Cincinnati Cancer Center-UC Medical Center, Cincinnati, Ohio
Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio
Bethesda North Hospital, Cincinnati, Ohio
TriHealth Cancer Institute-Westside, Cincinnati, Ohio
TriHealth Cancer Institute-Anderson, Cincinnati, Ohio
Case Western Reserve University, Cleveland, Ohio
MetroHealth Medical Center, Cleveland, Ohio
Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland, Ohio
Cleveland Clinic Foundation, Cleveland, Ohio
Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Columbus Oncology and Hematology Associates Inc, Columbus, Ohio
Riverside Methodist Hospital, Columbus, Ohio
Columbus NCI Community Oncology Research Program, Columbus, Ohio
Grant Medical Center, Columbus, Ohio
The Mark H Zangmeister Center, Columbus, Ohio
Mount Carmel Health Center West, Columbus, Ohio
Doctors Hospital, Columbus, Ohio
Grandview Hospital, Dayton, Ohio
Delaware Health Center-Grady Cancer Center, Delaware, Ohio
Delaware Radiation Oncology, Delaware, Ohio
Grady Memorial Hospital, Delaware, Ohio
Fairfield Medical Center, Lancaster, Ohio
Lancaster Radiation Oncology, Lancaster, Ohio
Marietta Memorial Hospital, Marietta, Ohio
Hillcrest Hospital Cancer Center, Mayfield Heights, Ohio
UH Seidman Cancer Center at Landerbrook Health Center, Mayfield Heights, Ohio
UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor, Ohio
Knox Community Hospital, Mount Vernon, Ohio
Licking Memorial Hospital, Newark, Ohio
Newark Radiation Oncology, Newark, Ohio
Southern Ohio Medical Center, Portsmouth, Ohio
Springfield Regional Medical Center, Springfield, Ohio
ProMedica Flower Hospital, Sylvania, Ohio
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio
University Hospitals Sharon Health Center, Wadsworth, Ohio
Saint Ann's Hospital, Westerville, Ohio
UHHS-Westlake Medical Center, Westlake, Ohio
Genesis Healthcare System Cancer Care Center, Zanesville, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Mercy Hospital Oklahoma City, Oklahoma City, Oklahoma
Oklahoma Cancer Specialists and Research Institute-Tulsa, Tulsa, Oklahoma
Saint Alphonsus Cancer Care Center-Baker City, Baker City, Oregon
Saint Charles Health System, Bend, Oregon
Clackamas Radiation Oncology Center, Clackamas, Oregon
Providence Cancer Institute Clackamas Clinic, Clackamas, Oregon
Bay Area Hospital, Coos Bay, Oregon
Legacy Mount Hood Medical Center, Gresham, Oregon
Providence Newberg Medical Center, Newberg, Oregon
Saint Alphonsus Cancer Care Center-Ontario, Ontario, Oregon
Providence Willamette Falls Medical Center, Oregon City, Oregon
Legacy Good Samaritan Hospital and Medical Center, Portland, Oregon
Providence Portland Medical Center, Portland, Oregon
Providence Saint Vincent Medical Center, Portland, Oregon
Jefferson Abington Hospital, Abington, Pennsylvania
Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania
Saint Luke's University Hospital-Bethlehem Campus, Bethlehem, Pennsylvania
Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania
Geisinger Medical Center, Danville, Pennsylvania
Easton Hospital, Easton, Pennsylvania
Geisinger Medical Center-Cancer Center Hazleton, Hazleton, Pennsylvania
Armstrong Center for Medicine and Health, Kittanning, Pennsylvania
Geisinger Medical Oncology-Lewisburg, Lewisburg, Pennsylvania
Lewistown Hospital, Lewistown, Pennsylvania
University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania
West Penn Hospital, Pittsburgh, Pennsylvania
Geisinger Cancer Services-Pottsville, Pottsville, Pennsylvania
Geisinger Medical Group, State College, Pennsylvania
Chester County Hospital, West Chester, Pennsylvania
Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania
Women and Infants Hospital, Providence, Rhode Island
Gibbs Cancer Center-Gaffney, Gaffney, South Carolina
Saint Francis Hospital, Greenville, South Carolina
Saint Francis Cancer Center, Greenville, South Carolina
Gibbs Cancer Center-Pelham, Greer, South Carolina
Spartanburg Medical Center, Spartanburg, South Carolina
SMC Center for Hematology Oncology Union, Union, South Carolina
Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota
Avera Cancer Institute, Sioux Falls, South Dakota
Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota
Memorial Hospital, Chattanooga, Tennessee
Pulmonary Medicine Center of Chattanooga-Hixson, Hixson, Tennessee
Memorial GYN Plus, Ooltewah, Tennessee
Saint Joseph Regional Cancer Center, Bryan, Texas
MD Anderson in The Woodlands, Conroe, Texas
Parkland Memorial Hospital, Dallas, Texas
UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas
Houston Methodist Hospital, Houston, Texas
M D Anderson Cancer Center, Houston, Texas
Memorial Hermann Texas Medical Center, Houston, Texas
MD Anderson West Houston, Houston, Texas
MD Anderson League City, League City, Texas
MD Anderson in Sugar Land, Sugar Land, Texas
Houston Methodist Sugar Land Hospital, Sugar Land, Texas
American Fork Hospital / Huntsman Intermountain Cancer Center, American Fork, Utah
Sandra L Maxwell Cancer Center, Cedar City, Utah
Logan Regional Hospital, Logan, Utah
Intermountain Medical Center, Murray, Utah
McKay-Dee Hospital Center, Ogden, Utah
Utah Valley Regional Medical Center, Provo, Utah
Saint George Regional Medical Center, Saint George, Utah
Utah Cancer Specialists-Salt Lake City, Salt Lake City, Utah
LDS Hospital, Salt Lake City, Utah
Providence Regional Cancer System-Aberdeen, Aberdeen, Washington
Cancer Care Center at Island Hospital, Anacortes, Washington
MultiCare Auburn Medical Center, Auburn, Washington
Virginia Mason Bainbridge Island Medical Center, Bainbridge Island, Washington
Overlake Medical Center, Bellevue, Washington
Swedish Cancer Institute-Eastside Oncology Hematology, Bellevue, Washington
PeaceHealth Saint Joseph Medical Center, Bellingham, Washington
Highline Medical Center-Main Campus, Burien, Washington
Providence Regional Cancer System-Centralia, Centralia, Washington
Swedish Cancer Institute-Edmonds, Edmonds, Washington
Saint Elizabeth Hospital, Enumclaw, Washington
Providence Regional Cancer Partnership, Everett, Washington
Virginia Mason Federal Way Medical Center, Federal Way, Washington
Saint Francis Hospital, Federal Way, Washington
Tacoma/Valley Radiation Oncology Centers-Gig Harbor, Gig Harbor, Washington
MultiCare Gig Harbor Medical Park, Gig Harbor, Washington
Swedish Cancer Institute-Issaquah, Issaquah, Washington
Kadlec Clinic Hematology and Oncology, Kennewick, Washington
Northwest Cancer Clinic, Kennewick, Washington
Providence Regional Cancer System-Lacey, Lacey, Washington
Saint Clare Hospital, Lakewood, Washington
PeaceHealth Saint John Medical Center, Longview, Washington
Virginia Mason Lynnwood Medical Center, Lynnwood, Washington
Jefferson Healthcare, Port Townsend, Washington
Harrison HealthPartners Hematology and Oncology-Poulsbo, Poulsbo, Washington
Peninsula Cancer Center, Poulsbo, Washington
MultiCare Good Samaritan Hospital, Puyallup, Washington
Tacoma/Valley Radiation Oncology Centers-Puyallup, Puyallup, Washington
Virginia Mason Medical Center, Seattle, Washington
Minor and James Medical PLLC, Seattle, Washington
Pacific Gynecology Specialists, Seattle, Washington
Swedish Medical Center-Ballard Campus, Seattle, Washington
Fred Hutchinson Cancer Center, Seattle, Washington
Kaiser Permanente Washington, Seattle, Washington
Swedish Medical Center-Cherry Hill, Seattle, Washington
Swedish Medical Center-First Hill, Seattle, Washington
University of Washington Medical Center - Northwest, Seattle, Washington
Women's Cancer Center of Seattle, Seattle, Washington
University of Washington Medical Center - Montlake, Seattle, Washington
Providence Regional Cancer System-Shelton, Shelton, Washington
Saint Michael Cancer Center, Silverdale, Washington
MultiCare Deaconess Cancer and Blood Specialty Center - Valley, Spokane Valley, Washington
MultiCare Deaconess Cancer and Blood Specialty Center - Downtown, Spokane, Washington
MultiCare Deaconess Cancer and Blood Specialty Center - North, Spokane, Washington
Tacoma/Valley Radiation Oncology Centers-Jackson Hall, Tacoma, Washington
Franciscan Research Center-Northwest Medical Plaza, Tacoma, Washington
MultiCare Tacoma General Hospital, Tacoma, Washington
Northwest Medical Specialties PLLC, Tacoma, Washington
Tacoma/Valley Radiation Oncology Centers-Saint Joe's, Tacoma, Washington
PeaceHealth Southwest Medical Center, Vancouver, Washington
Legacy Salmon Creek Hospital, Vancouver, Washington
Providence Saint Mary Regional Cancer Center, Walla Walla, Washington
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital, Yakima, Washington
Providence Regional Cancer System-Yelm, Yelm, Washington
Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin
Aurora Health Center-Fond du Lac, Fond Du Lac, Wisconsin
Aurora Health Care Germantown Health Center, Germantown, Wisconsin
Aurora Cancer Care-Grafton, Grafton, Wisconsin
Aurora BayCare Medical Center, Green Bay, Wisconsin
Mercyhealth Hospital and Cancer Center - Janesville, Janesville, Wisconsin
Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin
Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin
Aurora Cancer Care-Milwaukee, Milwaukee, Wisconsin
Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin
Medical College of Wisconsin, Milwaukee, Wisconsin
Aurora Sinai Medical Center, Milwaukee, Wisconsin
Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin
Aurora Cancer Care-Racine, Racine, Wisconsin
Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin
Aurora Medical Center in Summit, Summit, Wisconsin
Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin
Aurora Cancer Care-Waukesha, Waukesha, Wisconsin
Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin
Aurora West Allis Medical Center, West Allis, Wisconsin
Cheyenne Regional Medical Center-West, Cheyenne, Wyoming
Big Horn Basin Cancer Center, Cody, Wyoming
Billings Clinic-Cody, Cody, Wyoming
Welch Cancer Center, Sheridan, Wyoming
Bristol Royal Infirmary, Bristol, England
Addenbrookes Hospital-Medical School, Cambridge, England
Saint Bartholomew's Hospital, London, England
Hammersmith Hospital, London, England
University College London Hospital, London, England
Christie Hospital, Manchester, England
Musgrove Park Hospital, Somerset, England
Saint James's University Hospital, West Yorkshire, England
Belfast City Hospital, Belfast, Northern Ireland
Western General Hospital, Edinburgh, Scotland
Beatson Oncology Center, Glasgow, Scotland
The Royal Marsden NHS Foundation Trust-Chelsea, London, Not set
Nottingham City Hospital, Nottingham, Not set
Conditions: Micropapillary Serous Carcinoma, Ovarian Serous Adenocarcinoma, Primary Peritoneal Serous Adenocarcinoma, Recurrent Primary Peritoneal Serous Adenocarcinoma, Borderline Ovarian Serous Tumor, Recurrent Ovarian Low Grade Serous Adenocarcinoma
Study of Efficacy and Safety of Pembrolizumab Plus Platinum-based Doublet Chemotherapy With or Without Canakinumab in Previously Untreated Locally Advanced or Metastatic Non-squamous and Squamous NSCLC Subjects
Active Not Recruiting
This was a Phase III study of pembrolizumab plus platinum-based doublet chemotherapy with or without canakinumab in previously untreated locally advanced or metastatic non-squamous and squamous NSCLC participants.
This was a Phase III study of pembrolizumab plus platinum-based doublet chemotherapy with or without canakinumab in previously untreated locally advanced or metastatic non-squamous and squamous NSCLC participants. Read Less
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
08/12/2025
Locations: Pacific Shores Medical Group, Long Beach, California +152 locations
Pacific Shores Medical Group, Long Beach, California
USC Kenneth Norris Comprehensive Cancer Center, Los Angeles, California
Advent Health Cancer Institute, Orlando, Florida
Dana Farber Cancer Institute, Boston, Massachusetts
Novartis Investigative Site, Caba, Buenos Aires
Novartis Investigative Site, Caba, Not set
Novartis Investigative Site, Westmead, New South Wales
Novartis Investigative Site, Wooloongabba, Queensland
Novartis Investigative Site, Melbourne, Victoria
Novartis Investigative Site, Murdoch, Western Australia
Novartis Investigative Site, Linz, Oberoesterreich
Novartis Investigative Site, Salzburg, Not set
Novartis Investigative Site, Barretos, SP
Novartis Investigative Site, Sao Paulo, SP
Novartis Investigative Site, Sao Paulo, SP
Novartis Investigative Site, Edmonton, Alberta
Novartis Investigative Site, Brampton, Ontario
Novartis Investigative Site, Toronto, Ontario
Novartis Investigative Site, Temuco, Region De La Araucania
Novartis Investigative Site, Santiago, Not set
Novartis Investigative Site, Harbin, Heilongjiang
Novartis Investigative Site, Wuhan, Hubei
Novartis Investigative Site, Wuhan, Hubei
Novartis Investigative Site, Changsha, Hunan
Novartis Investigative Site, Changchun, Jilin
Novartis Investigative Site, XI An, Shanxi
Novartis Investigative Site, Hangzhou, Zhejiang
Novartis Investigative Site, Beijing, Not set
Novartis Investigative Site, Valledupar, Cesar
Novartis Investigative Site, Brno Bohunice, Not set
Novartis Investigative Site, Brno, Not set
Novartis Investigative Site, Ostrava Vitkovice, Not set
Novartis Investigative Site, Praha 2, Not set
Novartis Investigative Site, Herning, Not set
Novartis Investigative Site, Oulu, Not set
Novartis Investigative Site, Marseille, Bouches Du Rhone
Novartis Investigative Site, Lyon, Not set
Novartis Investigative Site, Montpellier, Not set
Novartis Investigative Site, Nantes Cedex 1, Not set
Novartis Investigative Site, Paris, Not set
Novartis Investigative Site, Goettingen, Niedersachsen
Novartis Investigative Site, Koeln, Nordrhein-Westfalen
Novartis Investigative Site, Halle Saale, Sachsen-Anhalt
Novartis Investigative Site, Leipzig, Sachsen
Novartis Investigative Site, Berlin, Not set
Novartis Investigative Site, Dresden, Not set
Novartis Investigative Site, Essen, Not set
Novartis Investigative Site, Georgsmarienhuette, Not set
Novartis Investigative Site, Gerlingen, Not set
Novartis Investigative Site, Heidelberg, Not set
Novartis Investigative Site, Koeln, Not set
Novartis Investigative Site, Muenchen, Not set
Novartis Investigative Site, Athens, GR
Novartis Investigative Site, Athens, Not set
Novartis Investigative Site, Kowloon, Not set
Novartis Investigative Site, Kowloon, Not set
Novartis Investigative Site, Veszprem, Not set
Novartis Investigative Site, Reykjavik, Not set
Novartis Investigative Site, Hyderabad, Andhra Pradesh
Novartis Investigative Site, Gurgaon, Haryana
Novartis Investigative Site, Pune, Maharashtra
Novartis Investigative Site, Jaipur, Rajasthan
Novartis Investigative Site, Hyderabad, Telangana
Novartis Investigative Site, Kolkata, West Bengal
Novartis Investigative Site, Avellino, AV
Novartis Investigative Site, Genova, GE
Novartis Investigative Site, Milano, MI
Novartis Investigative Site, Milano, MI
Novartis Investigative Site, Milano, MI
Novartis Investigative Site, Rozzano, MI
Novartis Investigative Site, Modena, MO
Novartis Investigative Site, Padova, PD
Novartis Investigative Site, Perugia, PG
Novartis Investigative Site, Parma, PR
Novartis Investigative Site, Orbassano, TO
Novartis Investigative Site, Nagoya, Aichi
Novartis Investigative Site, Sapporo city, Hokkaido
Novartis Investigative Site, Himeji, Hyogo
Novartis Investigative Site, Yokohama-city, Kanagawa
Novartis Investigative Site, Sakai, Osaka
Novartis Investigative Site, Sunto Gun, Shizuoka
Novartis Investigative Site, Chuo ku, Tokyo
Novartis Investigative Site, Ube-city, Yamaguchi
Novartis Investigative Site, Osaka, Not set
Novartis Investigative Site, Gyeonggi do, Korea
Novartis Investigative Site, Seoul, Seocho Gu
Novartis Investigative Site, Seoul, Not set
Novartis Investigative Site, Seoul, Not set
Novartis Investigative Site, Seoul, Not set
Novartis Investigative Site, Ashrafieh, Not set
Novartis Investigative Site, Saida, Not set
Novartis Investigative Site, Kuantan, Pahang
Novartis Investigative Site, Kuching, Sarawak
Novartis Investigative Site, Kuala Lumpur, Wilayah Persekutuan
Novartis Investigative Site, Kuala Lumpur, Not set
Novartis Investigative Site, Groningen, Not set
Novartis Investigative Site, Groningen, Not set
Novartis Investigative Site, Drammen, Not set
Novartis Investigative Site, Taguig City, Metro Manila
Novartis Investigative Site, Makati City, Not set
Novartis Investigative Site, Quezon, Not set
Novartis Investigative Site, San Juan City, Not set
Novartis Investigative Site, Gliwice, Not set
Novartis Investigative Site, Poznan, Not set
Novartis Investigative Site, Tomaszw Mazowiecki, Not set
Novartis Investigative Site, Lisboa, Not set
Novartis Investigative Site, Porto, Not set
Novartis Investigative Site, Craiova, Dolj
Novartis Investigative Site, Cluj-Napoca, Not set
Novartis Investigative Site, Arkhangelsk, Not set
Novartis Investigative Site, Omsk, Not set
Novartis Investigative Site, Pushkin Saint Petersburg, Not set
Novartis Investigative Site, Saint Petersburg, Not set
Novartis Investigative Site, St Petersburg, Not set
Novartis Investigative Site, Singapore, Not set
Novartis Investigative Site, Singapore, Not set
Novartis Investigative Site, Singapore, Not set
Novartis Investigative Site, Bratislava, Slovak Republic
Novartis Investigative Site, Partizanske, Not set
Novartis Investigative Site, Granada, Andalucia
Novartis Investigative Site, Badalona, Catalunya
Novartis Investigative Site, Barcelona, Catalunya
Novartis Investigative Site, San Sebastian, Pais Vasco
Novartis Investigative Site, Barcelona, Not set
Novartis Investigative Site, Las Palmas de Gran Canaria, Not set
Novartis Investigative Site, Madrid, Not set
Novartis Investigative Site, Madrid, Not set
Novartis Investigative Site, Madrid, Not set
Novartis Investigative Site, Madrid, Not set
Novartis Investigative Site, Malaga, Not set
Novartis Investigative Site, Valencia, Not set
Novartis Investigative Site, Zaragoza, Not set
Novartis Investigative Site, Stockholm, Not set
Novartis Investigative Site, Basel, Not set
Novartis Investigative Site, Kaohsiung, Not set
Novartis Investigative Site, Tainan, Not set
Novartis Investigative Site, Taipei, Not set
Novartis Investigative Site, Taipei, Not set
Novartis Investigative Site, Taoyuan, Not set
Novartis Investigative Site, Songkhla, Hat Yai
Novartis Investigative Site, Khon Kaen, THA
Novartis Investigative Site, Bangkok, Not set
Novartis Investigative Site, Bangkok, Not set
Novartis Investigative Site, Bangkok, Not set
Novartis Investigative Site, Ankara, Not set
Novartis Investigative Site, Ankara, Not set
Novartis Investigative Site, Edirne, Not set
Novartis Investigative Site, Istanbul, Not set
Novartis Investigative Site, High Heaton, Newcastle Upon Tyne
Novartis Investigative Site, London, Not set
Novartis Investigative Site, Manchester, Not set
Novartis Investigative Site, Plymouth, Not set
Novartis Investigative Site, Hanoi, Not set
Conditions: Non-small Cell Lung Cancer
Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy
Active Not Recruiting
This is a Phase II, multi-site, open-label, parallel group study in participants with untreated extended-stage small-cell lung cancer (ES-SCLC) (Cohort 1) or small-cell lung cancer (SCLC) which has progressed on first- or second-line treatment (Cohort 2 and Cohort 3). This study will assess the safety, efficacy, and pharmacokinetics (PK) of BNT327.
This is a Phase II, multi-site, open-label, parallel group study in participants with untreated extended-stage small-cell lung cancer (ES-SCLC) (Cohort 1) or small-cell lung cancer (SCLC) which has progressed on first- or second-line treatment (Cohort 2 and Cohort 3). This study will assess the safety, efficacy, and pharmacokinetics (PK) of BNT327. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2025
Locations: Alaska Oncology and Hematology, LLC, Anchorage, Alaska +63 locations
Alaska Oncology and Hematology, LLC, Anchorage, Alaska
Valkyrie Clinical Trials, Los Angeles, California
Clermont Oncology Center, Clermont, Florida
Hematology Oncology Associates of Treasure Coast, Port Saint Lucie, Florida
Tallahassee Memorial Physician Partners - Cancer & Hematology Specialists, Tallahassee, Florida
Carle Foundation Hospital d/b/a Carle Cancer Center, Urbana, Illinois
Fort Wayne Medical Oncology and Hematology, Inc, Fort Wayne, Indiana
University of Kentucky Chandler Medical Center (UKCMC) - Markey Cancer Center (Lucille P. Markey Cancer Center), Lexington, Kentucky
Allina Health, Minneapolis, Minnesota
SSM Health Cancer Care - St. Clare, Fenton, Missouri
Nebraska Hematology-Oncology (NHO) - Lincoln, Lincoln, Nebraska
Clinical Research Alliance Inc, Westbury, New York
Haywood Infusion Center, Clyde, North Carolina
FirstHealth Outpatient Cancer Center, Pinehurst, North Carolina
The Christ Hospital Cancer Center, Cincinnati, Ohio
University of Tennessee Medical Center, Knoxville, Tennessee
Millenium Research & Clinical Development, Houston, Texas
SSM Health Cancer Care, Madison, Wisconsin
Lyell McEwin Hospital, Adelaide, Not set
St. Vincent's Hospital, Fitzroy, Not set
Peninsula Oncology Centre, Frankston, Not set
Royal North Shore Hospital, St Leonards, Not set
Westmead Hospital, Westmead, Not set
Chungbuk National University Hospital, Cheongju-si, Not set
Yeungnam University Medical Center, Daegu, Not set
National Cancer Center, Goyang-si, Not set
Gachon University Gil Medical Center, Incheon, Not set
Gyeongsang National University Hospital (GNUH), Jinju-si, Not set
Korea University Anam Hospital, Seoul, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
The Catholic University of Korea Seoul St. Mary's Hospital, Seoul, Not set
Ajou University Hospital, Suwon-si, Not set
Baskent University Hospital Adana Dr Turgut Noyan Research Center, Adana, Not set
Medical Park Seyhan Hospital, Adana, Not set
Adana City Training and Research Hospital, Adana, Not set
Gulhane Egitim ve Arastirma Hastanesi, Ankara, Not set
Ankara Etlik Sehir Hastanesi, Ankara, Not set
Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara, Not set
Hacettepe University Medical Faculty Oncology Hospital, Ankara, Not set
Memorial Ankara Hospital, Ankara, Not set
Liv Hospital, Ankara, Not set
Ankara City Hospital, Ankara, Not set
Gaziantep Sanko University Medical Faculty, Gaziantep, Not set
Koc Universitesi Hastanesi (Koc University Hospital), Istanbul, Not set
Bezmialem Vakif Universitesi Tip Fakultesi Hastanesi, Istanbul, Not set
Acibadem Adana Hastanesi, Istanbul, Not set
Yeditepe University Kosuyolu Hospital, Istanbul, Not set
Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi, Istanbul, Not set
Medical Point Izmir Hospital, İzmir, Not set
Kocaeli Universitesi Tip Fakultesi, Kocaeli, Not set
Sakarya University - Faculty of Medicine, Sakarya, Not set
Namik Kemal University Hospital, Tekirdağ, Not set
Gazi University Medical Faculty, Yenimahalle, Not set
Queen Elizabeth Hospital Birmingham - University Hospitals Birmingham NHS Foundation Trust, Birmingham, Not set
Velindre Hospital - Velindre NHS Trust, Cardiff, Not set
Ninewells Hospital and Medical School - Tayside Health Board, Dundee, Not set
Royal Devon and Exeter Hospital, Wonford - Royal Devon And Exeter NHS Foundation Trust, Exeter, Not set
Huddersfield Royal Infirmary - Calderdale and Huddersfield NHS Foundation Trust, Huddersfield, Not set
St James's University Hospital - Leeds Teaching Hospitals NHS Trust, Leeds, Not set
Sarah Cannon Research Institute, London, Not set
Northern Centre for Cancer Care,The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, Not set
Nottingham University Hospitals NHS Trust, Nottingham, Not set
Royal Preston Hospital - Lancashire Teaching Hospitals NHS Foundation Trust, Preston, Not set
Royal Stoke University Hospital - University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, Not set
Conditions: Extensive-stage Small-cell Lung Cancer, Small-cell Lung Cancer
A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer
Recruiting
This is a Phase III, randomised, open-label, 3-arm, multicentre, international study assessing the efficacy and safety of Dato-DXd with or without durvalumab compared with investigator's choice chemotherapy in combination with pembrolizumab in participants with PD-L1 positive locally recurrent inoperable or metastatic TNBC.
This is a Phase III, randomised, open-label, 3-arm, multicentre, international study assessing the efficacy and safety of Dato-DXd with or without durvalumab compared with investigator's choice chemotherapy in combination with pembrolizumab in participants with PD-L1 positive locally recurrent inoperable or metastatic TNBC. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/11/2025
Locations: Research Site, Daphne, Alabama +307 locations
Research Site, Daphne, Alabama
Research Site, Springdale, Arkansas
Research Site, Duarte, California
Research Site, Glendale, California
Research Site, Sacramento, California
Research Site, Santa Rosa, California
Research Site, Aurora, Colorado
Research Site, New Haven, Connecticut
Research Site, Jacksonville, Florida
Research Site, Miami, Florida
Research Site, Palm Bay, Florida
Research Site, Plantation, Florida
Research Site, Atlanta, Georgia
Research Site, Honolulu, Hawaii
Research Site, Chicago, Illinois
Research Site, Decatur, Illinois
Research Site, Elmhurst, Illinois
Research Site, Naperville, Illinois
Research Site, New Albany, Indiana
Research Site, Des Moines, Iowa
Research Site, Lexington, Kentucky
Research Site, Louisville, Kentucky
Research Site, Louisville, Kentucky
Research Site, Louisville, Kentucky
Research Site, Baton Rouge, Louisiana
Research Site, Baton Rouge, Louisiana
Research Site, Baltimore, Maryland
Research Site, Columbia, Maryland
Research Site, Boston, Massachusetts
Research Site, Worcester, Massachusetts
Research Site, Detroit, Michigan
Research Site, Grand Rapids, Michigan
Research Site, Saint Paul, Minnesota
Research Site, Hattiesburg, Mississippi
Research Site, Saint Louis, Missouri
Research Site, Albuquerque, New Mexico
Research Site, Albany, New York
Research Site, New York, New York
Research Site, Stony Brook, New York
Research Site, Cincinnati, Ohio
Research Site, Cincinnati, Ohio
Research Site, Cleveland, Ohio
Research Site, York, Pennsylvania
Research Site, Providence, Rhode Island
Research Site, Chattanooga, Tennessee
Research Site, Nashville, Tennessee
Research Site, Dallas, Texas
Research Site, Dallas, Texas
Research Site, Dallas, Texas
Research Site, El Paso, Texas
Research Site, Flower Mound, Texas
Research Site, Fort Worth, Texas
Research Site, Houston, Texas
Research Site, Houston, Texas
Research Site, Houston, Texas
Research Site, Kingwood, Texas
Research Site, McKinney, Texas
Research Site, Sugar Land, Texas
Research Site, Charlottesville, Virginia
Research Site, Fairfax, Virginia
Research Site, Midlothian, Virginia
Research Site, Norfolk, Virginia
Research Site, Roanoke, Virginia
Research Site, Tacoma, Washington
Research Site, Madison, Wisconsin
Research Site, Buenos Aires, Not set
Research Site, Caba, Not set
Research Site, Caba, Not set
Research Site, Caba, Not set
Research Site, Ciudad de Buenos Aires, Not set
Research Site, Rosario, Not set
Research Site, San Nicolas de Los Arroyos, Not set
Research Site, Camperdown, Not set
Research Site, Darlinghurst, Not set
Research Site, Heidelberg, Not set
Research Site, Melbourne, Not set
Research Site, Nedlands, Not set
Research Site, Waratah, Not set
Research Site, Barretos, Not set
Research Site, Curitiba, Not set
Research Site, Florianópolis, Not set
Research Site, Goiânia, Not set
Research Site, Itajai, Not set
Research Site, Porto Alegre, Not set
Research Site, Recife, Not set
Research Site, Sao Paulo, Not set
Research Site, São Paulo, Not set
Research Site, Teresina, Not set
Research Site, Barrie, Ontario
Research Site, Hamilton, Ontario
Research Site, Toronto, Ontario
Research Site, Greenfield Park, Quebec
Research Site, Montréal, Quebec
Research Site, Montréal, Quebec
Research Site, Regina, Saskatchewan
Research Site, Saskatoon, Saskatchewan
Research Site, Quebec, Not set
Research Site, Anyang, Not set
Research Site, Beijing, Not set
Research Site, Beijing, Not set
Research Site, Bengbu, Not set
Research Site, Changchun, Not set
Research Site, Changsha, Not set
Research Site, Changsha, Not set
Research Site, Chengdu, Not set
Research Site, Chengdu, Not set
Research Site, Chongqing, Not set
Research Site, Fuzhou, Not set
Research Site, Guangzhou, Not set
Research Site, Guangzhou, Not set
Research Site, Guangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Harbin, Not set
Research Site, Hefei, Not set
Research Site, Ji Nan, Not set
Research Site, Nanchang, Not set
Research Site, Nanjing, Not set
Research Site, Nanjing, Not set
Research Site, Nanning, Not set
Research Site, Shandong, Not set
Research Site, Shanghai, Not set
Research Site, Shanghai, Not set
Research Site, Shenyang, Not set
Research Site, Tianjin, Not set
Research Site, Wenzhou, Not set
Research Site, Wuhan, Not set
Research Site, Wuhan, Not set
Research Site, Xi'an, Not set
Research Site, Xiamen, Not set
Research Site, Xintai, Not set
Research Site, Xuzhou, Not set
Research Site, Zhanjiang, Not set
Research Site, Zhengzhou, Not set
Research Site, Zhengzhou, Not set
Research Site, Lille, Not set
Research Site, Lyon, Not set
Research Site, Montpellier Cedex 5, Not set
Research Site, Paris, Not set
Research Site, Saint Herblain Cedex, Not set
Research Site, Toulouse Cedex 9, Not set
Research Site, Vandoeuvre-lès-nancy, Not set
Research Site, Villejuif, Not set
Research Site, Düsseldorf, Not set
Research Site, Essen, Not set
Research Site, Georgsmarienhütte, Not set
Research Site, Hamburg, Not set
Research Site, Hannover, Not set
Research Site, Heidelberg, Not set
Research Site, Heilbronn, Not set
Research Site, Leipzig, Not set
Research Site, Hong Kong, Not set
Research Site, Hong Kong, Not set
Research Site, Hong Kong, Not set
Research Site, Shatin, Not set
Research Site, Calicut, Not set
Research Site, Chennai, Not set
Research Site, Jaipur, Not set
Research Site, Kochi, Not set
Research Site, Kolkata, Not set
Research Site, Marg Jaipur, Not set
Research Site, Mohali, Not set
Research Site, Mysuru, Not set
Research Site, Nagpur, Not set
Research Site, Nashik, Not set
Research Site, New Delhi, Not set
Research Site, New Delhi, Not set
Research Site, Pondicherry, Not set
Research Site, Surat, Not set
Research Site, Thiruvananthapuram, Not set
Research Site, Vadodara, Not set
Research Site, Vishakapatnam, Not set
Research Site, Bergamo, Not set
Research Site, Empoli, Not set
Research Site, Milano, Not set
Research Site, Milan, Not set
Research Site, Modena, Not set
Research Site, Napoli, Not set
Research Site, Padova, Not set
Research Site, Reggio Emilia, Not set
Research Site, Roma, Not set
Research Site, Rozzano, Not set
Research Site, Akashi-shi, Not set
Research Site, Bunkyo-ku, Not set
Research Site, Bunkyo-ku, Not set
Research Site, Chiba-shi, Not set
Research Site, Chuo-ku, Not set
Research Site, Fukuoka-shi, Not set
Research Site, Fukushima-shi, Not set
Research Site, Gifu-shi, Not set
Research Site, Hidaka-shi, Not set
Research Site, Hiroshima-shi, Not set
Research Site, Hiroshima-shi, Not set
Research Site, Isehara-shi, Not set
Research Site, Kamogawa-shi, Not set
Research Site, Kashiwa, Not set
Research Site, Kitaadachi-gun, Not set
Research Site, Koto-ku, Not set
Research Site, Kumamoto-shi, Not set
Research Site, Kurume-shi, Not set
Research Site, Matsuyama-shi, Not set
Research Site, Nagoya-shi, Not set
Research Site, Nagoya-shi, Not set
Research Site, Niigata-shi, Not set
Research Site, Nishinomiya-shi, Not set
Research Site, Okayama-shi, Not set
Research Site, Osaka-shi, Not set
Research Site, Osakasayama-shi, Not set
Research Site, Ota-shi, Not set
Research Site, Sapporo-shi, Not set
Research Site, Sendai-shi, Not set
Research Site, Shinagawa-ku, Not set
Research Site, Shinjuku-ku, Not set
Research Site, Shinjuku-ku, Not set
Research Site, Tsu-shi, Not set
Research Site, Tsukuba, Not set
Research Site, Yokohama-shi, Not set
Research Site, Busan, Not set
Research Site, Daegu, Not set
Research Site, Goyang-si, Not set
Research Site, Seongnam-si, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, CD Mexico, Not set
Research Site, Guadalajara, Not set
Research Site, Guadalajara, Not set
Research Site, Mexico City, Not set
Research Site, Mexico, Not set
Research Site, México, Not set
Research Site, Tuxtla Gutierrez, Not set
Research Site, Bacolod, Not set
Research Site, Cebu City, Not set
Research Site, Manila, Not set
Research Site, Muntinlupa City, Not set
Research Site, Quezon City, Not set
Research Site, San Juan, Not set
Research Site, Białystok, Not set
Research Site, Bydgoszcz, Not set
Research Site, Gdańsk, Not set
Research Site, Gdynia, Not set
Research Site, Konin, Not set
Research Site, Kraków, Not set
Research Site, Legnica, Not set
Research Site, Lublin, Not set
Research Site, Przemysl, Not set
Research Site, Warszawa, Not set
Research Site, Wroclaw, Not set
Research Site, Łódź, Not set
Research Site, Singapore, Not set
Research Site, Singapore, Not set
Research Site, Singapore, Not set
Research Site, Singapore, Not set
Research Site, Cape Town, Not set
Research Site, Johannesburg, Not set
Research Site, Johannesburg, Not set
Research Site, Johannesburg, Not set
Research Site, Paarl, Not set
Research Site, Pretoria, Not set
Research Site, Barcelona, Not set
Research Site, Barcelona, Not set
Research Site, Granada, Not set
Research Site, Hospitalet deLlobregat, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, Pamplona, Not set
Research Site, Santander, Not set
Research Site, Hsinchu, Not set
Research Site, Kaohsiung, Not set
Research Site, Taichung, Not set
Research Site, Tainan, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taoyuan, Not set
Research Site, Bangkok, Not set
Research Site, Bangkok, Not set
Research Site, Bangkok, Not set
Research Site, Chiang Mai, Not set
Research Site, Dusit, Not set
Research Site, Khon Kaen, Not set
Research Site, Songkhla, Not set
Research Site, Ankara, Not set
Research Site, Ankara, Not set
Research Site, Besevler Ankara, Not set
Research Site, Izmir, Not set
Research Site, Küçükçekmece, Not set
Research Site, Samsun, Not set
Research Site, Cardiff, Not set
Research Site, Chelsea, Not set
Research Site, Leicester, Not set
Research Site, Liverpool, Not set
Research Site, London, Not set
Research Site, London, Not set
Research Site, Oxford, Not set
Research Site, Surrey, Not set
Research Site, Sutton, Not set
Research Site, Taunton, Not set
Research Site, Hanoi, Not set
Research Site, Ho Chi Minh City, Not set
Research Site, Hue, Not set
Research Site, Hồ Chí Minh, Not set
Research Site, Viet Tri, Not set
Research Site, Vinh, Not set
Conditions: Breast Cancer
A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors
Completed
The purpose of this open-label nonrandomized Phase 1/2 study is to evaluate INCB001158 in combination with chemotherapy in participants with advanced/metastatic solid tumors.
The purpose of this open-label nonrandomized Phase 1/2 study is to evaluate INCB001158 in combination with chemotherapy in participants with advanced/metastatic solid tumors. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/08/2025
Locations: University of Alabama, Birmingham, Alabama +9 locations
University of Alabama, Birmingham, Alabama
USA Mitchell Cancer Center, Mobile, Alabama
UC Davis - Comprehensive Cancer Centre, Sacramento, California
Northwest Georgia Oncology Centers, Marietta, Georgia
The University of Texas MD Anderson Cancer Center, Houston, Texas
START San Antonio, San Antonio, Texas
Grand Hopital de Charleroi - Department of Medical Oncology, Brussels, Not set
Institut Jules Bordet - Clinical Trials Conduct Unit, Brussels, Not set
UCL Cancer Institute, London, Not set
The Christie NHS Foundation Trust, Manchester, Not set
Conditions: Biliary Tract Cancer (BTC), Colorectal Cancer (CRC), Endometrial Cancer, Gastroesophageal Cancer (GC), Ovarian Cancer, Solid Tumors
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
Recruiting
This is an umbrella study evaluating the efficacy and safety of multiple treatment combinations in participants with metastatic or inoperable locally advanced breast cancer.
The study will be performed in two stages. During Stage 1, four cohorts will be enrolled in parallel in this study:
Cohort 1 will consist of Programmed death-ligand 1 (PD-L1)-positive participants who have received no prior systemic therapy for metastatic or inoperable locally advanced triple-negative breast cancer (TNBC)... Read More
This is an umbrella study evaluating the efficacy and safety of multiple treatment combinations in participants with metastatic or inoperable locally advanced breast cancer.
The study will be performed in two stages. During Stage 1, four cohorts will be enrolled in parallel in this study:
Cohort 1 will consist of Programmed death-ligand 1 (PD-L1)-positive participants who have received no prior systemic therapy for metastatic or inoperable locally advanced triple-negative breast cancer (TNBC) (first-line \[1L\] PD-L1+ cohort).
Cohort 2 will consist of participants who had disease progression during or following 1L treatment with chemotherapy for metastatic or inoperable locally-advanced TNBC and have not received cancer immunotherapy (CIT) (second-line \[2L\] CIT-naive cohort).
Cohort 3 will consist of participants with locally-advanced or metastatic HR+, HER2-negative disease with PIK3CA mutation who may or may not have had disease progression during or following previous lines of treatment for metastatic disease (HR+cohort).
Cohort 4 will consist of participants with locally-advanced or metastatic HER2+ /HER2-low disease with PIK3CA mutation who had disease progression on standard-of-care therapies (HER2+ /HER2-low cohort).
In each cohort, eligible participants will initially be assigned to one of several treatment arms (Stage 1). In addition, participants in the 2L CIT-naïve cohort who experience disease progression, loss of clinical benefit, or unacceptable toxicity during Stage 1 may be eligible to continue treatment with a different treatment combination (Stage 2), provided Stage 2 is open for enrollment. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/07/2025
Locations: City of Hope, Duarte, California +41 locations
City of Hope, Duarte, California
University of California San Diego Medical Center, La Jolla, California
Stanford Cancer Institute, Stanford, California
Rocky Mountain Cancer Center - Longmont, Longmont, Colorado
H. Lee Moffitt Cancer Center and Research Inst., Tampa, Florida
Hackensack Univ Medical Center, Hackensack, New Jersey
Regional Cancer Care Associates, LLC, Howell, New Jersey
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
NYU Langone Medical Center, New York, New York
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
The West Clinic, Germantown, Tennessee
Vanderbilt University Medical Center, Nashville, Tennessee
Texas Oncology-Plano East, Plano, Texas
Peter MacCallum Cancer Centre-East Melbourne, Melbourne, Victoria
Fiona Stanley Hospital - Medical Oncology, Murdoch, Western Australia
Centre Léon Bérard, Lyon, Not set
Institut régional du Cancer Montpellier, Montpellier, Not set
Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, Not set
Gustave Roussy, Villejuif, Not set
Universitätsklinikum Erlangen, Erlangen, Not set
Universitätsklinikum Essen, Essen, Not set
Rambam Medical Center, Haifa, Not set
Shaare Zedek Medical Center, Jerusalem, Not set
Hadassah University Medical Center, Jerusalem, Not set
Rabin MC, Petach Tikva, Not set
Sheba Medical Center, Ramat Gan, Not set
Tel-Aviv Sourasky Medical Center, Tel Aviv, Not set
Assuta Medical Centers, Tel Aviv, Not set
National Cancer Center Clinical Trials Center / Center for Breast Cancer, Goyang-si, Not set
Seoul National University Hospital, Seoul, Not set
Severance Hospital, Seoul, Not set
University of Ulsan College of Medicine - Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Hospital del Mar, Barcelona, Not set
Vall d?Hebron Institute of Oncology (VHIO), Barcelona, Barcelona, Not set
Hospital Universitario Ramon y Cajal, Madrid, Not set
Centro Integral Oncológico Clara Campal Ensayos Clínicos START, Madrid, Not set
Hospital Universitario Virgen Macarena, Sevilla, Not set
National Cheng Kung University Hospital, Tainan City, Not set
Beatson West of Scotland Cancer Centre, Glasgow, Not set
Barts Health NHS Trust - St Bartholomew's Hospital, London, Not set
Conditions: Metastatic Breast Cancer
13 - 24 of 293