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Paclitaxel Treatment Options in United Kingdom
A collection of 293 research studies where Paclitaxel is the interventional treatment. These studies are located in the United Kingdom . Paclitaxel is used for conditions such as Breast Cancer, Ovarian Cancer and Non-Small Cell Lung Cancer.
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Study of Durvalumab + Tremelimumab With Chemotherapy or Durvalumab With Chemotherapy or Chemotherapy Alone for Patients With Lung Cancer (POSEIDON).
Active Not Recruiting
This is a randomized, open-label, multi-center, global, Phase III study to determine the efficacy and safety of durvalumab + tremelimumab combination therapy + Standard of care (SoC) chemotherapy or durvalumab monotherapy + SoC chemotherapy versus SoC chemotherapy alone as first line treatment in patients with metastatic non small-cell lung cancer (NSCLC) with tumors that lack activating epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) fusions.
This is a randomized, open-label, multi-center, global, Phase III study to determine the efficacy and safety of durvalumab + tremelimumab combination therapy + Standard of care (SoC) chemotherapy or durvalumab monotherapy + SoC chemotherapy versus SoC chemotherapy alone as first line treatment in patients with metastatic non small-cell lung cancer (NSCLC) with tumors that lack activating epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) fusions. Read Less
Gender:
ALL
Ages:
Between 18 years and 130 years
Trial Updated:
06/11/2025
Locations: Research Site, Phoenix, Arizona +174 locations
Research Site, Phoenix, Arizona
Research Site, Bakersfield, California
Research Site, Santa Monica, California
Research Site, Fort Myers, Florida
Research Site, Jacksonville, Florida
Research Site, Saint Petersburg, Florida
Research Site, West Palm Beach, Florida
Research Site, Louisville, Kentucky
Research Site, Kansas City, Missouri
Research Site, Canton, Ohio
Research Site, Pittsburgh, Pennsylvania
Research Site, Chattanooga, Tennessee
Research Site, Nashville, Tennessee
Research Site, Fort Worth, Texas
Research Site, Houston, Texas
Research Site, Richmond, Virginia
Research Site, Barretos, Not set
Research Site, Belo Horizonte, Not set
Research Site, Curitiba, Not set
Research Site, Porto Alegre, Not set
Research Site, Porto Alegre, Not set
Research Site, Porto Alegre, Not set
Research Site, Ribeirao Preto, Not set
Research Site, Rio de Janeiro, Not set
Research Site, Santo Andre, Not set
Research Site, Santo André, Not set
Research Site, Sao Paulo, Not set
Research Site, São José do Rio Preto, Not set
Research Site, São Paulo, Not set
Research Site, São Paulo, Not set
Research Site, Plovdiv, Not set
Research Site, Plovdiv, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Varna, Not set
Research Site, Beijing, Not set
Research Site, Beijing, Not set
Research Site, Changchun, Not set
Research Site, Changsha, Not set
Research Site, Fuzhou, Not set
Research Site, Guangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Harbin, Not set
Research Site, Hefei, Not set
Research Site, Kunming, Not set
Research Site, Linyi, Not set
Research Site, Liuzhou, Not set
Research Site, Nanjing, Not set
Research Site, Qingdao, Not set
Research Site, Shanghai, Not set
Research Site, Shanghai, Not set
Research Site, Shanghai, Not set
Research Site, Shantou, Not set
Research Site, Wuhan, Not set
Research Site, Wuhan, Not set
Research Site, Xining, Not set
Research Site, Yangzhou, Not set
Research Site, Zhanjiang, Not set
Research Site, Zhengzhou, Not set
Research Site, Zhengzhou, Not set
Research Site, Berlin, Not set
Research Site, Essen, Not set
Research Site, Freiburg, Not set
Research Site, Gauting, Not set
Research Site, Hamburg, Not set
Research Site, Hamburg, Not set
Research Site, Heidelberg, Not set
Research Site, Immenhausen, Not set
Research Site, Mainz, Not set
Research Site, Oldenburg, Not set
Research Site, Würzburg, Not set
Research Site, Shatin, Not set
Research Site, Budapest, Not set
Research Site, Budapest, Not set
Research Site, Kecskemét, Not set
Research Site, Miskolc, Not set
Research Site, Törökbálint, Not set
Research Site, Bunkyo-ku, Not set
Research Site, Chuo-ku, Not set
Research Site, Fukuoka-shi, Not set
Research Site, Hiroshima-shi, Not set
Research Site, Iwakuni-shi, Not set
Research Site, Kanazawa, Not set
Research Site, Kashiwa, Not set
Research Site, Koto-ku, Not set
Research Site, Kurume-shi, Not set
Research Site, Matsuyama-shi, Not set
Research Site, Okayama-shi, Not set
Research Site, Okayama-shi, Not set
Research Site, Osakasayama, Not set
Research Site, Sapporo-shi, Not set
Research Site, Sunto-gun, Not set
Research Site, Toyoake-shi, Not set
Research Site, Ube-shi, Not set
Research Site, Yokohama-shi, Not set
Research Site, Yokohama-shi, Not set
Research Site, Busan, Not set
Research Site, Chungcheongbuk-do, Not set
Research Site, Daegu, Not set
Research Site, Incheon, Not set
Research Site, Seongnam-si, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Ulsan, Not set
Research Site, Aguascalientes, Not set
Research Site, Cuautitlan Izcalli, Not set
Research Site, Guadalajara, Not set
Research Site, Mexico City, Not set
Research Site, Mexico, Not set
Research Site, Monterrey, Not set
Research Site, Monterrey, Not set
Research Site, México, Not set
Research Site, Tuxtla, Not set
Research Site, Arequipa, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, San Isidro, Not set
Research Site, Olsztyn, Not set
Research Site, Tomaszów Mazowiecki, Not set
Research Site, Warszawa, Not set
Research Site, Wodzisław Śląski, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Omsk, Not set
Research Site, Saint Petersburg, Not set
Research Site, Saint-Petersburg, Not set
Research Site, Sankt-Peterburg, Not set
Research Site, St. Petersburg, Not set
Research Site, Cape Town, Not set
Research Site, Durban, Not set
Research Site, Johannesburg, Not set
Research Site, Parktown, Not set
Research Site, Pretoria, Not set
Research Site, Rondebosch, Not set
Research Site, Vereeniging, Not set
Research Site, Changhua City, Not set
Research Site, Kaohsiung City, Not set
Research Site, Kaohsiung, Not set
Research Site, Taichung, Not set
Research Site, Taichung, Not set
Research Site, Tainan, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Tao-Yuan, Not set
Research Site, Bangkok, Not set
Research Site, Bangkok, Not set
Research Site, Bangkok, Not set
Research Site, Muang, Not set
Research Site, Songkhla, Not set
Research Site, Dnipro, Not set
Research Site, Ivano-Frankivsk, Not set
Research Site, Kirovohrad, Not set
Research Site, Kyiv, Not set
Research Site, Kyiv, Not set
Research Site, Lviv, Not set
Research Site, Odesa, Not set
Research Site, Sumy, Not set
Research Site, Vinnytsia, Not set
Research Site, Zaporizhzhia, Not set
Research Site, Leicester, Not set
Research Site, London, Not set
Research Site, London, Not set
Research Site, London, Not set
Research Site, Manchester, Not set
Research Site, Hanoi, Not set
Research Site, Ho Chi Minh, Not set
Conditions: Non Small Cell Lung Cancer NSCLC
Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer
Active Not Recruiting
This study will evaluate the efficacy, safety and tolerability of trastuzumab deruxtecan compared with investigator's choice chemotherapy in human epidermal growth factor receptor (HER)2-low, hormone receptor (HR) positive breast cancer patients whose disease has progressed on endocrine therapy in the metastatic setting.
This study will evaluate the efficacy, safety and tolerability of trastuzumab deruxtecan compared with investigator's choice chemotherapy in human epidermal growth factor receptor (HER)2-low, hormone receptor (HR) positive breast cancer patients whose disease has progressed on endocrine therapy in the metastatic setting. Read Less
Gender:
ALL
Ages:
Between 18 years and 105 years
Trial Updated:
06/09/2025
Locations: Research Site, Scottsdale, Arizona +293 locations
Research Site, Scottsdale, Arizona
Research Site, Springdale, Arkansas
Research Site, Duarte, California
Research Site, Los Angeles, California
Research Site, Aurora, Colorado
Research Site, Lakewood, Colorado
Research Site, Washington, District of Columbia
Research Site, Jacksonville, Florida
Research Site, Kansas City, Kansas
Research Site, Louisville, Kentucky
Research Site, Bethesda, Maryland
Research Site, Boston, Massachusetts
Research Site, Detroit, Michigan
Research Site, Rochester, Minnesota
Research Site, Saint Louis, Missouri
Research Site, Summit, New Jersey
Research Site, Westbury, New York
Research Site, Columbus, Ohio
Research Site, Pittsburgh, Pennsylvania
Research Site, Nashville, Tennessee
Research Site, Austin, Texas
Research Site, Dallas, Texas
Research Site, Houston, Texas
Research Site, Houston, Texas
Research Site, Norfolk, Virginia
Research Site, Seattle, Washington
Research Site, Madison, Wisconsin
Research Site, Buenos Aires, Not set
Research Site, Caba, Not set
Research Site, Caba, Not set
Research Site, Caba, Not set
Research Site, Ciudad de Buenos Aires, Not set
Research Site, Cordoba, Not set
Research Site, La Plata, Not set
Research Site, Mar del Plata, Not set
Research Site, Rosario, Not set
Research Site, Rosario, Not set
Research Site, Adelaide, Not set
Research Site, Birtinya, Not set
Research Site, Darlinghurst, Not set
Research Site, Murdoch, Not set
Research Site, South Brisbane, Not set
Research Site, St Leonards, Not set
Research Site, Waratah, Not set
Research Site, Graz, Not set
Research Site, Innsbruck, Not set
Research Site, Anderlecht, Not set
Research Site, Bruxelles, Not set
Research Site, Charleroi, Not set
Research Site, Edegem, Not set
Research Site, Gent, Not set
Research Site, Leuven, Not set
Research Site, Liège, Not set
Research Site, Namur, Not set
Research Site, Roeselare, Not set
Research Site, Sint-Niklaas, Not set
Research Site, Barretos, Not set
Research Site, Belo Horizonte, Not set
Research Site, Natal, Not set
Research Site, Porto Alegre, Not set
Research Site, Porto Alegre, Not set
Research Site, Rio de Janeiro, Not set
Research Site, Sao Paulo, Not set
Research Site, Sorocaba, Not set
Research Site, São Paulo, Not set
Research Site, Calgary, Alberta
Research Site, Edmonton, Alberta
Research Site, Vancouver, British Columbia
Research Site, Toronto, CA
Research Site, London, Ontario
Research Site, Toronto, Ontario
Research Site, Toronto, Ontario
Research Site, Montreal, Quebec
Research Site, Montreal, Quebec
Research Site, Sherbrooke, Quebec
Research Site, Baoding, Not set
Research Site, Beijing, Not set
Research Site, Beijing, Not set
Research Site, Changchun, Not set
Research Site, Changsha, Not set
Research Site, Changsha, Not set
Research Site, Dalian, Not set
Research Site, Foshan, Not set
Research Site, Fuzhou, Not set
Research Site, Guangzhou, Not set
Research Site, Guangzhou, Not set
Research Site, Guangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Harbin, Not set
Research Site, Hefei, Not set
Research Site, Jinan, Not set
Research Site, Linyi, Not set
Research Site, Nanchang, Not set
Research Site, Nanchang, Not set
Research Site, Nanjing, Not set
Research Site, Nanjing, Not set
Research Site, Nanning, Not set
Research Site, Shanghai, Not set
Research Site, Shenyang, Not set
Research Site, Tianjin, Not set
Research Site, Urumqi, Not set
Research Site, Wuhan, Not set
Research Site, Xi'an, Not set
Research Site, Xi'an, Not set
Research Site, Zhengzhou, Not set
Research Site, Aalborg, Not set
Research Site, Copenhagen Ø, Not set
Research Site, Odense, Not set
Research Site, Vejle, Not set
Research Site, Avignon Cedex 09, Not set
Research Site, Besançon, Not set
Research Site, Bordeaux, Not set
Research Site, Brest, Not set
Research Site, Caen Cedex 05, Not set
Research Site, Dijon, Not set
Research Site, Le Mans, Not set
Research Site, Marseille, Not set
Research Site, Montpellier, Not set
Research Site, Nice, Not set
Research Site, Paris, Not set
Research Site, Pierre Benite, Not set
Research Site, Plerin SUR MER, Not set
Research Site, Rennes, Not set
Research Site, Saint Herblain Cedex, Not set
Research Site, Saint-cloud, Not set
Research Site, Tours, Not set
Research Site, Villejuif Cedex, Not set
Research Site, Berlin, Not set
Research Site, Dresden, Not set
Research Site, Freiburg, Not set
Research Site, Hannover, Not set
Research Site, München, Not set
Research Site, München, Not set
Research Site, Münster, Not set
Research Site, Velbert, Not set
Research Site, Budapest, Not set
Research Site, Budapest, Not set
Research Site, Budapest, Not set
Research Site, Győr, Not set
Research Site, Kecskemét, Not set
Research Site, Nyíregyháza, Not set
Research Site, Szolnok, Not set
Research Site, Tatabánya, Not set
Research Site, Bengaluru, Not set
Research Site, Calicut, Not set
Research Site, Kolkata, Not set
Research Site, Marg Jaipur, Not set
Research Site, New Delhi, Not set
Research Site, New Delhi, Not set
Research Site, New Delhi, Not set
Research Site, New Delhi, Not set
Research Site, Surat, Not set
Research Site, Thiruvananthapuram, Not set
Research Site, Haifa, Not set
Research Site, Jerusalem, Not set
Research Site, Jerusalem, Not set
Research Site, Kfar-Saba, Not set
Research Site, Petah Tikva, Not set
Research Site, Ramat Gan, Not set
Research Site, Tel-Aviv, Not set
Research Site, Aviano, Not set
Research Site, Bergamo, Not set
Research Site, Candiolo, Not set
Research Site, Cona, Not set
Research Site, Genova, Not set
Research Site, Livorno, Not set
Research Site, Messina, Not set
Research Site, Milano, Not set
Research Site, Milan, Not set
Research Site, Napoli, Not set
Research Site, Padova, Not set
Research Site, Parma, Not set
Research Site, Prato, Not set
Research Site, Tricase, Lecce, Not set
Research Site, Udine, Not set
Research Site, Akashi-shi, Not set
Research Site, Bunkyo-ku, Not set
Research Site, Chiba-shi, Not set
Research Site, Chuo-ku, Not set
Research Site, Fukuoka-shi, Not set
Research Site, Gifu-shi, Not set
Research Site, Hidaka-shi, Not set
Research Site, Hiroshima-shi, Not set
Research Site, Isehara, Not set
Research Site, Kagoshima-shi, Not set
Research Site, Kashiwa, Not set
Research Site, Kawasaki-shi, Not set
Research Site, Kitaadachi-gun, Not set
Research Site, Koto-ku, Not set
Research Site, Matsuyama-shi, Not set
Research Site, Nagoya, Not set
Research Site, Naha-shi, Not set
Research Site, Niigata-shi, Not set
Research Site, Nishinomiya-shi, Not set
Research Site, Okayama-shi, Not set
Research Site, Osaka-shi, Not set
Research Site, Osakasayama-shi, Not set
Research Site, Sagamihara-shi, Not set
Research Site, Sapporo-shi, Not set
Research Site, Shinagawa-ku, Not set
Research Site, Shinjuku-ku, Not set
Research Site, Shizuoka, Not set
Research Site, Tsu-shi, Not set
Research Site, Yokohama-shi, Not set
Research Site, Daegu, Not set
Research Site, Goyang-si, Not set
Research Site, Incheon, Not set
Research Site, Seongnam-si, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Alc. Cuauhtémoc, Not set
Research Site, Guadalajara Jalisco, Not set
Research Site, Guadalajra, Not set
Research Site, Mexico City, Not set
Research Site, Mexico City, Not set
Research Site, Mexico, D.F., Not set
Research Site, Monterrey, Not set
Research Site, México, Not set
Research Site, Nuevo Leon, Not set
Research Site, Amsterdam, Not set
Research Site, Breda, Not set
Research Site, Hengelo, Not set
Research Site, Leeuwarden, Not set
Research Site, Rotterdam, Not set
Research Site, Sittard-Geleen, Not set
Research Site, Bydgoszcz, Not set
Research Site, Koszalin, Not set
Research Site, Kraków, Not set
Research Site, Rzeszów, Not set
Research Site, Warszawa, Not set
Research Site, Wroclaw, Not set
Research Site, Łódź, Not set
Research Site, Lisboa, Not set
Research Site, Lisboa, Not set
Research Site, Lisboa, Not set
Research Site, Krasnodar, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Saint Petersburg, Not set
Research Site, Saint Petersburg, Not set
Research Site, Saint-Petersburg, Not set
Research Site, Sankt-Peterburg, Not set
Research Site, Yaroslavl, Not set
Research Site, Ar Riyāḑ, Not set
Research Site, Dammam, Not set
Research Site, Jeddah, Not set
Research Site, Jeddah, Not set
Research Site, Riyadh, Not set
Research Site, Riyadh, Not set
Research Site, Bukit Merah, Not set
Research Site, Singapore, Not set
Research Site, Singapore, Not set
Research Site, Singapore, Not set
Research Site, Singapore, Not set
Research Site, Barcelona, Not set
Research Site, Barcelona, Not set
Research Site, Barcelona, Not set
Research Site, Cordoba, Not set
Research Site, El Palmar, Not set
Research Site, La Coruña, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, San Sebastián, Not set
Research Site, Sevilla, Not set
Research Site, Valencia, Not set
Research Site, Göteborg, Not set
Research Site, Stockholm, Not set
Research Site, Uppsala, Not set
Research Site, Växjö, Not set
Research Site, Örebro, Not set
Research Site, Taichung, Not set
Research Site, Tainan, Not set
Research Site, Tainan, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Tao-Yuan, Not set
Research Site, Cambridge, Not set
Research Site, Cardiff, Not set
Research Site, Edinburgh, Not set
Research Site, Guildford, Not set
Research Site, Leeds, Not set
Research Site, London, Not set
Research Site, Manchester, Not set
Research Site, Northwood, Not set
Conditions: Advanced or Metastatic Breast Cancer
Study of Durvalumab With Tremelimumab Versus SoC as 1st Line Therapy in Metastatic Non Small-Cell Lung Cancer (NSCLC) (NEPTUNE)
Active Not Recruiting
This is a randomized, open-label, multi-center, global, Phase III study to determine the efficacy and safety of durvalumab + tremelimumab combination therapy versus platinum-based SoC chemotherapy in the first-line treatment of patients with epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) wild-type advanced or metastatic NSCLC.
This is a randomized, open-label, multi-center, global, Phase III study to determine the efficacy and safety of durvalumab + tremelimumab combination therapy versus platinum-based SoC chemotherapy in the first-line treatment of patients with epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) wild-type advanced or metastatic NSCLC. Read Less
Gender:
ALL
Ages:
Between 18 years and 130 years
Trial Updated:
06/06/2025
Locations: Research Site, Anaheim, California +210 locations
Research Site, Anaheim, California
Research Site, San Diego, California
Research Site, Santa Rosa, California
Research Site, Louisville, Kentucky
Research Site, Florham Park, New Jersey
Research Site, Albuquerque, New Mexico
Research Site, East Setauket, New York
Research Site, Fresh Meadows, New York
Research Site, Poughkeepsie, New York
Research Site, Stony Brook, New York
Research Site, Canton, Ohio
Research Site, Columbus, Ohio
Research Site, Zanesville, Ohio
Research Site, Pittsburgh, Pennsylvania
Research Site, Houston, Texas
Research Site, Berazategui, Not set
Research Site, Buenos Aires, Not set
Research Site, Caba, Not set
Research Site, Córdoba, Not set
Research Site, La Rioja, Not set
Research Site, Rosario, Not set
Research Site, San Salvador de Jujuy, Not set
Research Site, Santa Rosa, Not set
Research Site, Barretos, Not set
Research Site, Belo Horizonte, Not set
Research Site, Belo Horizonte, Not set
Research Site, Fortaleza, Not set
Research Site, Ijui, Not set
Research Site, Itajai, Not set
Research Site, Porto Alegre, Not set
Research Site, Porto Alegre, Not set
Research Site, Porto Alegre, Not set
Research Site, Sao Paulo, Not set
Research Site, Sao Paulo, Not set
Research Site, Sao Paulo, Not set
Research Site, São José do Rio Preto, Not set
Research Site, São Paulo, Not set
Research Site, Plovdiv, Not set
Research Site, Shumen, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Varna, Not set
Research Site, Vratza, Not set
Research Site, Santiago, Not set
Research Site, Santiago, Not set
Research Site, Santiago, Not set
Research Site, Santiago, Not set
Research Site, Santiago, Not set
Research Site, Temuco, Not set
Research Site, Viña del Mar, Not set
Research Site, Beijing, Not set
Research Site, Changchun, Not set
Research Site, Chongqing, Not set
Research Site, Guangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Shanghai, Not set
Research Site, Shanghai, Not set
Research Site, Urumqi, Not set
Research Site, Wuhan, Not set
Research Site, Wuhan, Not set
Research Site, Odense C, Not set
Research Site, Oulu, Not set
Research Site, Tampere, Not set
Research Site, Athens, Not set
Research Site, Athens, Not set
Research Site, Athens, Not set
Research Site, Heraklion, Not set
Research Site, Holargos, Athens, Not set
Research Site, Ioannina, Not set
Research Site, Hong Kong, Not set
Research Site, King's Park, Not set
Research Site, Shatin, Not set
Research Site, Ahmedabad, Not set
Research Site, Bangalore, Not set
Research Site, Bangalore, Not set
Research Site, Chennai, Not set
Research Site, Gurgaon, Not set
Research Site, Karamsad, Not set
Research Site, New Delhi, Not set
Research Site, Beer Sheva, Not set
Research Site, Jerusalem, Not set
Research Site, Kfar Saba, Not set
Research Site, Nahariya, Not set
Research Site, Petah Tikva, Not set
Research Site, Ramat Gan, Not set
Research Site, Bunkyo-ku, Not set
Research Site, Fukushima-shi, Not set
Research Site, Habikino-shi, Not set
Research Site, Hirosaki-shi, Not set
Research Site, Iizuka-shi, Not set
Research Site, Iwakuni-shi, Not set
Research Site, Kanazawa, Not set
Research Site, Kishiwada-shi, Not set
Research Site, Kobe-shi, Not set
Research Site, Kurume-shi, Not set
Research Site, Kyoto-shi, Not set
Research Site, Mitaka-shi, Not set
Research Site, Nagaoka-shi, Not set
Research Site, Nagoya-shi, Not set
Research Site, Nagoya-shi, Not set
Research Site, Niigata-shi, Not set
Research Site, Okayama-shi, Not set
Research Site, Osaka-shi, Not set
Research Site, Saga-shi, Not set
Research Site, Sagamihara-shi, Not set
Research Site, Sakai-shi, Not set
Research Site, Sendai-shi, Not set
Research Site, Tokushima-shi, Not set
Research Site, Ube-shi, Not set
Research Site, Wakayama-shi, Not set
Research Site, Yokohama-shi, Not set
Research Site, Yokohama-shi, Not set
Research Site, Daegu, Not set
Research Site, Hwasun-gun, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Kuala Lumpur, Not set
Research Site, Kuantan, Not set
Research Site, Kuching, Not set
Research Site, Acapulco, Not set
Research Site, Aguascalientes, Not set
Research Site, Mexico, Not set
Research Site, Monterrey, Not set
Research Site, Mérida, Not set
Research Site, México, Not set
Research Site, Arequipa, Not set
Research Site, Bellavista, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Baguio City, Not set
Research Site, Cebu, Not set
Research Site, Las Pinas City, Not set
Research Site, Manila, Not set
Research Site, Manila, Not set
Research Site, Quezon City, Not set
Research Site, Bydgoszcz, Not set
Research Site, Kielce, Not set
Research Site, Kraków, Not set
Research Site, Mrozy, Not set
Research Site, Olsztyn, Not set
Research Site, Poznan, Not set
Research Site, Poznań, Not set
Research Site, Warszawa, Not set
Research Site, Warszawa, Not set
Research Site, Wodzisław Śląski, Not set
Research Site, Łódź, Not set
Research Site, Amadora, Not set
Research Site, Lisboa, Not set
Research Site, Porto, Not set
Research Site, Porto, Not set
Research Site, Porto, Not set
Research Site, Doha, Not set
Research Site, Suceava, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Omsk, Not set
Research Site, Saint Petersburg, Not set
Research Site, Saint Petersburg, Not set
Research Site, Saint-Petersburg, Not set
Research Site, Saint-Petersburg, Not set
Research Site, St. Petersburg, Not set
Research Site, Dammam, Not set
Research Site, Riyadh, Not set
Research Site, Riyadh, Not set
Research Site, Singapore, Not set
Research Site, Singapore, Not set
Research Site, Singapore, Not set
Research Site, Singapore, Not set
Research Site, Eskilstuna, Not set
Research Site, Linköping, Not set
Research Site, Stockholm, Not set
Research Site, Uppsala, Not set
Research Site, Adana, Not set
Research Site, Ankara, Not set
Research Site, Ankara, Not set
Research Site, Ankara, Not set
Research Site, Ankara, Not set
Research Site, Istanbul, Not set
Research Site, Istanbul, Not set
Research Site, Istanbul, Not set
Research Site, Izmir, Not set
Research Site, Chernivtsі, Not set
Research Site, Dnipro, Not set
Research Site, Ivano-Frankivsk, Not set
Research Site, Kapitanivka Village, Not set
Research Site, Kharkiv Region, Not set
Research Site, Kirovohrad, Not set
Research Site, Kyiv, Not set
Research Site, Kyiv, Not set
Research Site, Lviv, Not set
Research Site, Lyutizh, Not set
Research Site, Odesa, Not set
Research Site, Sumy, Not set
Research Site, Uzhhorod, Not set
Research Site, Vinnytsia, Not set
Research Site, Guildford, Not set
Research Site, London, Not set
Research Site, London, Not set
Research Site, London, Not set
Research Site, Manchester, Not set
Research Site, Nottingham, Not set
Research Site, Taunton, Not set
Research Site, Wirral, Not set
Research Site, Wolverhampton, Not set
Conditions: Non Small Cell Lung Carcinoma NSCLC
Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)
Active Not Recruiting
The purpose of this study is to compare pembrolizumab + adjuvant chemotherapy with placebo + adjuvant chemotherapy, with or without radiotherapy, with respect to disease-free survival (DFS) as assessed radiographically by the investigator or by histopathologic confirmation of suspected disease recurrence, and with respect to overall survival (OS). The primary hypotheses are that pembrolizumab + adjuvant chemotherapy is superior to placebo + adjuvant chemotherapy, with or without radiotherapy, wi... Read More
The purpose of this study is to compare pembrolizumab + adjuvant chemotherapy with placebo + adjuvant chemotherapy, with or without radiotherapy, with respect to disease-free survival (DFS) as assessed radiographically by the investigator or by histopathologic confirmation of suspected disease recurrence, and with respect to overall survival (OS). The primary hypotheses are that pembrolizumab + adjuvant chemotherapy is superior to placebo + adjuvant chemotherapy, with or without radiotherapy, with respect to DFS as assessed radiographically by the investigator or by histopathologic confirmation of suspected disease recurrence, and with respect to OS. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
06/05/2025
Locations: University of Alabama - Birmingham ( Site 3061), Birmingham, Alabama +230 locations
University of Alabama - Birmingham ( Site 3061), Birmingham, Alabama
University of South Alabama, Mitchell Cancer Institute ( Site 3058), Mobile, Alabama
HonorHealth Research Institute - Biltmore ( Site 3043), Phoenix, Arizona
Arizona Oncology Associates PC- HOPE ( Site 3049), Tucson, Arizona
UCSD Moores Cancer Center ( Site 3053), La Jolla, California
University Of Colorado ( Site 3051), Aurora, Colorado
Smilow Cancer Hospital at Yale New Haven ( Site 3070), New Haven, Connecticut
Mount Sinai Cancer Center ( Site 3081), Miami Beach, Florida
Northside Hospital ( Site 3036), Atlanta, Georgia
Northwestern Memorial Hospital ( Site 3044), Chicago, Illinois
Parkview Cancer Institute ( Site 3067), Fort Wayne, Indiana
Indiana University Melvin and Bren Simon Cancer Center ( Site 3071), Indianapolis, Indiana
University of Iowa Hospital and Clinics ( Site 3046), Iowa City, Iowa
Norton Cancer Institute - St. Matthews ( Site 3056), Louisville, Kentucky
WK Physicians Network/Gynecologic Oncology Associates ( Site 3047), Shreveport, Louisiana
University of Massachusetts Medical School ( Site 3037), Worcester, Massachusetts
Montefiore Medical Center ( Site 3065), Bronx, New York
Perlmutter Cancer Center at NYU Langone Hospital - Long Island ( Site 3076), Mineola, New York
Laura and Isaac Perlmutter Cancer Center at NYU Langone Health ( Site 3042), New York, New York
Duke Cancer Center ( Site 3072), Durham, North Carolina
Sanford Fargo Medical Center-Roger Maris Cancer Center ( Site 3080), Fargo, North Dakota
The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C, Columbus, Ohio
Legacy Good Samaritan Medical Center ( Site 3033), Portland, Oregon
Sidney Kimmel Cancer Center - Jefferson Health ( Site 3078), Philadelphia, Pennsylvania
AHN West Penn Hospital ( Site 3060), Pittsburgh, Pennsylvania
Abington Hospital - Asplundh Cancer Center ( Site 3073), Willow Grove, Pennsylvania
Sanford Gynecology Oncology ( Site 3045), Sioux Falls, South Dakota
UT Southwestern Medical Center ( Site 3063), Dallas, Texas
VCU Massey Cancer Center ( Site 3068), Richmond, Virginia
Centro de Oncología e Investigación de Buenos Aires ( Site 1005), Berazategui, Buenos Aires
IDIM Instituto de Diagnostico e Investigaciones Metabolicas ( Site 1006), Caba, Buenos Aires
Instituto de Investigaciones Clinicas Mar del Plata ( Site 1003), Mar del Plata, Buenos Aires
Hospital Britanico de Buenos Aires ( Site 1002), Buenos Aires, Caba
Instituto de Oncologia de Rosario ( Site 1004), Rosario, Santa Fe
IDIM - Instituto de Diagnóstico e Investigaciones Metabólicas ( Site 1010), Buenos Aires, Not set
Hospital Aleman ( Site 1001), Buenos Aires, Not set
CEMIC ( Site 1009), Buenos Aires, Not set
Centro Oncologico Riojano Integral ( Site 1007), La Rioja, Not set
Medizinische Universitat Graz ( Site 2004), Graz, Steiermark
Medizinische Universitaet Innsbruck ( Site 2001), Innsbruck, Tirol
Saint-Luc UCL ( Site 2042), Bruxelles, Bruxelles-Capitale, Region De
C.I.U. Hopital Ambroise Pare ( Site 2039), Mons, Hainaut
CHR Verviers ( Site 2035), Verviers, Liege
OLV Ziekenhuis ( Site 2038), Aalst, Oost-Vlaanderen
AZ Maria Middelares Gent ( Site 2032), Gent, Oost-Vlaanderen
Universitair Ziekenhuis Gent ( Site 2037), Gent, Oost-Vlaanderen
AZ Nikolaas ( Site 2031), Sint-Niklaas, Oost-Vlaanderen
UZ Leuven ( Site 2040), Leuven, Vlaams-Brabant
AZ Groeninge ( Site 2036), Kortrijk, West-Vlaanderen
CHC - Groupe Sante ( Site 2041), Liege, Not set
CHU Liege Sart-Tilman ( Site 2044), Liege, Not set
Tom Baker Cancer Centre ( Site 3007), Calgary, Alberta
Kingston Health Sciences Centre ( Site 3003), Kingston, Ontario
Centre Hospitalier de l Universite de Montreal - CHUM ( Site 3006), Montreal, Quebec
McGill University Health Centre ( Site 3005), Montreal, Quebec
Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 3, Quebec City, Quebec
Centro Investigación del Cáncer James Lind ( Site 1061), Temuco, Araucania
Fundacion Arturo Lopez Perez FALP ( Site 1062), Santiago, Region M. De Santiago
Centro de Cancer Nuestra Senora de la Esperanza ( Site 1063), Santiago, Region M. De Santiago
Bradfordhill-Clinical Area ( Site 1070), Santiago, Region M. De Santiago
Oncocentro ( Site 1065), Vina del Mar, Valparaiso
Anhui Provincial Hospital-Obstetrics and Gynecology ( Site 4034), Hefei, Anhui
Beijing Cancer Hospital ( Site 4048), Beijing, Beijing
Peking Union Medical College Hospital ( Site 4036), Beijing, Beijing
Chongqing Cancer Hospital ( Site 4040), Chongqing, Chongqing
The First Affiliated Hospital of Xiamen University ( Site 4060), Xiamen, Fujian
The First Affiliated Hospital ( Site 4043), Guangzhou, Guangdong
Guangxi Medical University Affiliated Tumor Hospital ( Site 4049), Nanning, Guangxi
Harbin Medical University Cancer Hospital ( Site 4033), Harbin, Heilongjiang
Hubei Cancer Hospital ( Site 4059), Wuhan, Hubei
Xiangya Hospital Central-South University ( Site 4035), Changsha, Hunan
Hunan Cancer Hospital ( Site 4050), Changsha, Hunan
Nanjing Drum Tower Hospital ( Site 4037), Nanjing, Jiangsu
Jiangxi Maternal and Child Health Hospital ( Site 4051), Nanchang, Jiangxi
The First Bethune Hospital of Jilin University ( Site 4057), Changchun, Jilin
The First Affiliated Hospital of Xi an Jiaotong University ( Site 4045), XI An, Shaanxi
Obstetrics and Gynecology Hosp. Fudan University ( Site 4041), Shanghai, Shanghai
Shanghai Renji Hospital Affiliated to Jiao Tong University ( Site 4053), Shanghai, Shanghai
Shanghai First Maternity and Infant Hospital-Gynecology department ( Site 4001), Shanghai, Shanghai
Sichuan Cancer Hospital ( Site 4039), Chengdu, Sichuan
Tianjin Medical University Cancer Institute & Hospital ( Site 4054), Tianjin, Tianjin
Yunnan Province Cancer Hospital-Gynecology Department ( Site 4055), Kunming, Yunnan
The First Affiliated Hospital, Zhejiang University-Gynecology ( Site 4002), Hangzhou, Zhejiang
Women s Hospital School of Medicine Zhejiang University ( Site 4032), Hangzhou, Zhejiang
The First Affiliated Hospital of Wenzhou Medical University ( Site 4056), Wenzhou, Zhejiang
Clínica Vida Fundación - Sede Poblado ( Site 1096), Medellin, Antioquia
Instituto Nacional de Cancerología E.S.E ( Site 1094), Bogota, Distrito Capital De Bogota
Instituto Cancerologico de Narino Ltda ( Site 1092), San Juan De Pasto, Narino
Fundacion Valle del Lili ( Site 1093), Cali, Valle Del Cauca
Fakultní nemocnice Brno Bohunice-Gynekologicko-porodnicka klinika ( Site 2394), Brno, Brno-mesto
Fakultni nemocnice Kralovske Vinohrady ( Site 2393), Praha, Praha 10
Vseobecna fakultni nemocnice v Praze ( Site 2391), Praha, Praha 2
Fakultni nemocnice Olomouc ( Site 2392), Olomouc, Not set
Rigshospitalet University Hospital ( Site 2515), Copehagen, Hovedstaden
Herlev Hospital ( Site 2514), Herlev, Hovedstaden
Aalborg Universitetshospital ( Site 2511), Aalborg, Nordjylland
Roskilde Sygehus ( Site 2513), Roskilde, Sjaelland
Odense Universitetshospital ( Site 2512), Odense, Syddanmark
Tampere University Hospital ( Site 2541), Tampere, Pirkanmaa
Kuopio University Hospital ( Site 2543), Kuopio, Pohjois-Savo
Turku University Hospital ( Site 2542), Turku, Varsinais-Suomi
Institut De Cancerologie De Lorraine ( Site 2072), Vandoeuvre les Nancy, Ain
Centre Antoine Lacassagne ( Site 2073), Nice, Alpes-Maritimes
Centre Francois Baclesse ( Site 2062), Caen, Calvados
Hôpital Privé Des Côtes d'Armor ( Site 2063), Plérin, Cotes-d Armor
CHU Besancon - Hopital Jean Minjoz ( Site 2068), Besancon, Doubs
Institut Bergonie ( Site 2067), Bordeaux, Gironde
Institut Universitaire du Cancer Toulouse - Oncopole ( Site 2065), Toulouse, Haute-Garonne
Institut Regional du Cancer de Montpellier - ICM ( Site 2069), Montpellier, Herault
Hopital Cochin ( Site 2070), Paris, Ile-de-France
Gustave Roussy ( Site 2071), Villejuif, Ile-de-France
Hopital prive du Confluent ( Site 2061), Nantes, Loire-Atlantique
Centre Hospitalier Lyon Sud ( Site 2064), Pierre Benite, Rhone
SLK-Kliniken Heilbronn GmbH ( Site 2116), Heilbronn, Baden-Wurttemberg
Klinikum Ludwigsburg ( Site 2111), Ludwigsburg, Baden-Wurttemberg
Universitaetsklinikum Tuebingen ( Site 2113), Tübingen, Baden-Wurttemberg
Medizinische Hochschule Hannover-Department of Obstetrics and Gynecology ( Site 2109), Hannover, Niedersachsen
Universitätsklinikum Bonn-Gynaecological oncology ( Site 2103), Bonn, Nordrhein-Westfalen
Kliniken Essen-Mitte, Evangelische Huyssens-Stiftung ( Site 2105), Essen, Nordrhein-Westfalen
Universitaetsklinikum Carl Gustav Carus Dresden-Klinik und Poliklinik für Frauenheilkunde und Gebur, Dresden, Sachsen
Universitätsklinikum Schleswig-Holstein ( Site 2101), Lübeck, Schleswig-Holstein
General Hospital of Patras. St Andrews ( Site 2421), Patras, Achaia
Geniko Panepistimako Nosokomeio ARETEIO ( Site 2423), Athens, Attiki
Perifereiako Geniko Nosokomeio ALEXANDRA ( Site 2425), Athens, Attiki
Athens University Hospital ATTIKON ( Site 2424), Chaidari, Attiki
Hospital Hygeia ( Site 2426), Marousi, Attiki
Euromedica General Clinic of Thessaloniki ( Site 2422), Thessaloniki, Not set
Rambam Medical Center ( Site 2307), Haifa, Not set
Edith Wolfson Medical Center ( Site 2306), Holon, Not set
Hadassah Medical Center. Ein Kerem ( Site 2303), Jerusalem, Not set
Rabin Medical Center ( Site 2305), Petah Tikva, Not set
Chaim Sheba Medical Center ( Site 2301), Ramat Gan, Not set
Istittuto Nazionale dei Tumori Regina Elena IRCCS - IFO ( Site 2121), Roma, Abruzzo
Fondazione Policlinico Universitario Agostino Gemelli ( Site 2124), Roma, Lazio
Istituto di Candiolo - IRCCS ( Site 2125), Candiolo, Piemonte
Azienda Ospedaliera Spedali Civili di Brescia ( Site 2135), Brescia, Not set
IRCCS Ospedale San Raffaele ( Site 2130), Milano, Not set
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 2122), Milano, Not set
Istituto Europeo di Oncologia IRCCS-Divisione di Ginecologia Oncologica ( Site 2132), Milano, Not set
Azienda Ospedaliera Universitaria Federico II ( Site 2123), Napoli, Not set
Istituto Nazionale Tumori IRCCS Fondazione Pascale ( Site 2127), Napoli, Not set
Istituto Oncologico Veneto IRCCS-Oncologia 2 ( Site 2134), Padova, Not set
Aichi Cancer Center Hospital ( Site 4190), Nagoya, Aichi
National Cancer Center Hospital East ( Site 4197), Kashiwa, Chiba
National Hospital Organization Shikoku Cancer Center ( Site 4181), Matsuyama, Ehime
Ehime University Hospital ( Site 4187), Toon, Ehime
Kurume University Hospital ( Site 4186), Kurume, Fukuoka
Gunma Prefectural Cancer Center ( Site 4183), Ota, Gunma
Hokkaido University Hospital ( Site 4194), Sapporo, Hokkaido
Hyogo Cancer Center ( Site 4195), Akashi, Hyogo
Iwate Medical University Hospital ( Site 4189), Shiwa-gun, Iwate
University of the Ryukyus Hospital ( Site 4184), Nakagami-gun, Okinawa
Saitama Medical University International Medical Center ( Site 4182), Hidaka, Saitama
Shizuoka Cancer Center Hospital and Research Institute ( Site 4192), Sunto-gun, Shizuoka
National Hospital Organization Kyushu Cancer Center ( Site 4193), Fukuoka, Not set
Niigata Cancer Center Hospital ( Site 4185), Niigata, Not set
Osaka International Cancer Institute ( Site 4188), Osaka, Not set
The Cancer Institute Hospital of JFCR ( Site 4196), Tokyo, Not set
Keio University Hospital ( Site 4191), Tokyo, Not set
National Cancer Center ( Site 4065), Goyang-si, Kyonggi-do
Seoul National University Bundang Hospital ( Site 4063), Seongnam-si, Kyonggi-do
Severance Hospital Yonsei University Health System ( Site 4062), Seoul, Not set
Asan Medical Center ( Site 4061), Seoul, Not set
Samsung Medical Center ( Site 4064), Seoul, Not set
Investigacion Onco Farmaceutica S de RL de CV ( Site 1127), La Paz, Baja California Sur
Hospital San Lucas Cardiologica del Sureste ( Site 1122), Tuxtla Gutierrez, Chiapas
Instituto Nacional de Cancerologia ( Site 1124), Cdmx, Distrito Federal
Christus Muguerza Clinica Vidriera ( Site 1125), Monterrey, Nuevo Leon
I Can Oncology Center SA de CV ( Site 1126), Monterrey, Nuevo Leon
Hospital Angeles Roma ( Site 1123), Ciudad de Mexico, Not set
Centro Oncologico Internacional. SEDNA ( Site 1121), Mexico City, Not set
University Hospital of North Norway ( Site 2153), Tromso, Troms
Soerlandet sykehus HF Kristiansand ( Site 2152), Kristiansand, Vest-Agder
Oslo Universitetssykehus Radiumhospitalet ( Site 2151), Oslo, Not set
Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 2487), Siedlce, Mazowieckie
Szpital Kliniczny im Ks Anny Mazowieckiej ( Site 2481), Warszawa, Mazowieckie
Bialostockie Centrum Onkologii ( Site 2483), Bialystok, Podlaskie
Narodowy Instytut Onkologii - Oddzial w Gliwicach ( Site 2482), Gliwice, Slaskie
Swietokrzyskie Centrum Onkologii SPZOZ ( Site 2485), Kielce, Swietokrzyskie
SPZOZ MSWIA z Warminsko-Mazurskim Centrum Onkologii w Olsztynie ( Site 2486), Olsztyn, Warminsko-mazurskie
Wielkopolskie Centrum Onkologii im.M.Sklodowskiej-Curie ( Site 2484), Poznan, Wielkopolskie
Arkhangelsk Clinical Oncological Dispensary ( Site 2637), Arkhangelsk, Arkhangel Skaya Oblast
Republican Clinical Oncology Dispensary of Republic of Bashkortostan ( Site 2645), Ufa, Baskortostan, Respublika
Chelyabinsk Regional Clinical Center Oncology and Nuclear Medicine ( Site 2644), Chelyabinsk, Chelyabinskaya Oblast
Krasnoyarsk Regional Clinical oncology dispensary ( Site 2643), Krasnoyarsk, Krasnoyarskiy Kray
National Research Ogarev Mordovia State University ( Site 2648), Saransk, Mordoviya, Respublika
FSBI National Medical Oncology Research Center n.a. N.N. Blokhina ( Site 2634), Moscow, Moskva
Moscow Research Oncology Institute named after P.A. Hertsen ( Site 2631), Moscow, Moskva
Nizhegorodsky Regional Oncology Dispensary-chemotherapy department (Branch№1) ( Site 2639), Nizhniy Novgorod, Nizhegorodskaya Oblast
Samara Regional Clinical Oncology Center-Chemotherapy Dapartment ( Site 2649), Samara, Samarskaya Oblast
Scientific Research Oncology Institute n.a. N.N.Petrov ( Site 2636), Saint-Petersburg, Sankt-Peterburg
Republican Clinical Oncology Dispensary of Tatarstan MoH ( Site 2646), Kazan, Tatarstan, Respublika
Tomsk Scientific Research Institute of Oncology-Chemotherapy ( Site 2638), Tomsk, Tomskaya Oblast
Yaroslavl Regional SBIH Clinical Oncology Hospital ( Site 2641), Yaroslavl, Yaroslavskaya Oblast
Hospital Josep Trueta ( Site 2184), Girona, Gerona
Clinica Universitaria de Navarra ( Site 2181), Madrid, Madrid, Comunidad De
Hospital Vall D Hebron ( Site 2182), Barcelona, Not set
Hospital Clinic i Provincial ( Site 2185), Barcelona, Not set
Hospital Universitario Reina Sofia ( Site 2183), Cordoba, Not set
Hospital Clinico San Carlos ( Site 2187), Madrid, Not set
Hospital Universitario La Paz ( Site 2186), Madrid, Not set
Universitetssjukhuset i Linkoping. ( Site 2222), Linkoping, Ostergotlands Lan
Karolinska Universitetssjukhuset Solna ( Site 2220), Solna, Stockholms Lan
Blod-och Tumorsjukdomar ( Site 2221), Uppsala, Uppsala Lan
Changhua Christian Hospital ( Site 4095), Changhua, Not set
Taichung Veterans General Hospital ( Site 4094), Taichung, Not set
MacKay Memorial Hospital ( Site 4092), Taipei, Not set
Taipei Veterans General Hospital ( Site 4093), Taipei, Not set
Linkou Chang Gung Memorial Hospital ( Site 4091), Taoyuan, Not set
Baskent Adana Dr Turgut Noyan Uygulama ve Arastirma Merkezi ( Site 2355), Adana, Not set
Cukurova Uni. Tip Fakultesi ( Site 2353), Adana, Not set
Baskent Universitesi Ankara Hastanesi ( Site 2354), Ankara, Not set
Ankara Universitesi Tıp Fakultesi Hastanesi ( Site 2350), Ankara, Not set
Medipol Universite Hastanesi ( Site 2352), Istanbul, Not set
Ege University Medical Faculty ( Site 2351), Izmir, Not set
I.E.U. Medical Point Hastanesi ( Site 2356), Izmir, Not set
Chernihiv Medical Center of Modern Oncology ( Site 2368), Chernihiv, Chernihivska Oblast
Municipal Enterprise "Bukovinian сlinical oncology сenter" ( Site 2366), Chernivtsi, Chernivetska Oblast
SO Grigoriev Institute for Medical Radiology and Oncology of NAMS of Ukraine ( Site 2363), Kharkiv, Kharkivska Oblast
MNE "Khmelnytskyi regional antitumor center" ( Site 2365), Khmelnitskyi, Khmelnytska Oblast
LISOD - Israeli Oncological Hospital MedX-ray International Group, LLC ( Site 2364), Kiev, Kyivska Oblast
Lviv State Regional Oncological Center ( Site 2361), Lviv, Lvivska Oblast
The Municipal Enterprise Volyn Regional Medical Oncology Centre ( Site 2362), Lutsk, Volynska Oblast
Bristol Haematology and Oncology Centre ( Site 2244), Bristol, Bristol, City Of
Castle Hill Hospital-Academic Oncology ( Site 2252), Cottingham, East Riding Of Yorkshire
Beatson West of Scotland Cancer Centre ( Site 2247), Glasgow, Glasgow City
UCLH NHS Foundation Trust ( Site 2242), London, London, City Of
Royal Marsden NHS Foundation Trust ( Site 2248), London, London, City Of
Royal Marsden Hospital Sutton-Surrey ( Site 2241), Sutton, London, City Of
Leicester Royal Infirmary. Univ. Hosp. of Leicester NHS Trust ( Site 2249), Leicester, Not set
The Christie Hospital NHS Foundation Trust ( Site 2243), Manchester, Not set
Conditions: Endometrial Neoplasms
Lenvatinib in Combination With Pembrolizumab Versus Treatment of Physician's Choice in Participants With Advanced Endometrial Cancer (MK-3475-775/E7080-G000-309 Per Merck Standard Convention [KEYNOTE-775])
Completed
This is a study of pembrolizumab (MK-3475, KEYTRUDA®) in combination with lenvatinib (E7080) versus treatment of physician's choice (doxorubicin or paclitaxel) for the treatment of advanced endometrial cancer. Participants will be randomly assigned to receive either pembrolizumab and lenvatinib or treatment of physician's choice. The primary study hypothesis is that pembrolizumab in combination with lenvatinib prolongs progression free survival (PFS) and overall survival (OS) when compared to tr... Read More
This is a study of pembrolizumab (MK-3475, KEYTRUDA®) in combination with lenvatinib (E7080) versus treatment of physician's choice (doxorubicin or paclitaxel) for the treatment of advanced endometrial cancer. Participants will be randomly assigned to receive either pembrolizumab and lenvatinib or treatment of physician's choice. The primary study hypothesis is that pembrolizumab in combination with lenvatinib prolongs progression free survival (PFS) and overall survival (OS) when compared to treatment of physician's choice. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
06/05/2025
Locations: Arizona Oncology Associates, PC- HAL, Phoenix, Arizona +168 locations
Arizona Oncology Associates, PC- HAL, Phoenix, Arizona
University of California San Francisco, San Francisco, California
University of California Los Angeles, Santa Monica, California
Smilow Cancer Hospital at Yale New Haven, New Haven, Connecticut
University of Miami Health System, Miami, Florida
Florida Hospital Cancer Institute, Orlando, Florida
Georgia Cancer Center at Augusta University, Augusta, Georgia
North Shore University Health System, Evanston, Illinois
University Medical Center New Orleans, New Orleans, Louisiana
Greater Baltimore Medical Center, Baltimore, Maryland
Maryland Oncology Hematology, P.A., Wheaton, Maryland
John Theurer Cancer Center at Hackensack University Med Ctr, Hackensack, New Jersey
Holy Name Medical Center, Teaneck, New Jersey
Memorial Sloan Kettering Cancer Center, New York, New York
University of Rochester, Rochester, New York
Duke University Medical Center, Durham, North Carolina
Stephenson Cancer Center, Oklahoma City, Oklahoma
Willamette Valley Cancer Institute and Research Center, Eugene, Oregon
Sanford Gynecology Oncology, Sioux Falls, South Dakota
UT West Cancer Center, Germantown, Tennessee
Texas Oncology-South Austin, Austin, Texas
University of Texas Southwestern Medical Center at Dallas, Dallas, Texas
The University of Texas MD Anderson Cancer Center, Houston, Texas
Texas Oncology-San Antonio Medical Center, San Antonio, Texas
Utah Cancer Specialists, Salt Lake City, Utah
Centro de Oncologia e Investigacion Buenos Aires COIBA, Berazategui, Buenos Aires
Hospital Privado de la Comunidad, Mar del Plata, Buenos Aires
Instituto de Investigaciones Metabolicas, Buenos Aires, Not set
Hospital Aleman, Buenos Aires, Not set
Instituto de Oncologia Angel H. Roffo, Buenos Aires, Not set
Instituto Medico Especializado Alexander Fleming, Buenos Aires, Not set
Centro Oncologico Riojano Integral, La Rioja, Not set
Royal North Shore Hospital, Sydney, New South Wales
Royal Brisbane and Women s Hospital, Herston, Queensland
Peter MacCallum Cancer Centre, Melbourne, Victoria
St John of God, Subiaco, Western Australia
Hospital Araujo Jorge, Goiania, GO
Instituto Nacional do Cancer II, Rio de Janeiro, RJ
Hospital de Clinicas de Porto Alegre, Porto Alegre, RS
Uniao Brasileira de Educacao e Assistencia Hospital Sao Lucas da Pucrs, Porto Alegre, RS
Fundacao Dr Amaral Carvalho, Jau, SP
Instituto do Cancer de Sao Paulo - ICESP, Sao Paulo, SP
Clinica de Pesquisas e Ctro de Estudos Onc. Ginecol. e Mamaria Ltda, Sao Paulo, SP
Faculdade de Medicina da Universidade Federal de Minas Gerais, Belo Horizonte, Not set
Tom Baker Cancer Centre, Calgary, Alberta
Cancer Care Manitoba, Winnipeg, Manitoba
London Health Sciences Centre, London, Ontario
Ottawa General Hospital, Ottawa, Ontario
Sunnybrook Health Science Centre, Toronto, Ontario
Princess Margaret Cancer Centre, Toronto, Ontario
CIUSSS de l Est de L Ile de Montreal - Hopital Maisonneuve-Rosemont, Montreal, Quebec
Centre Hospitalier de l Universite de Montreal - CHUM, Montreal, Quebec
Jewish General Hospital, Montreal, Quebec
CIUSSS de l'Estrie-CHUS, Sherbrooke, Quebec
CHU de Quebec-Universite Laval-Hotel Dieu de Quebec, Quebec, Not set
Clinica del Country, Bogota, Cundinamarca
Fundacion Valle del Lili, Cali, Valle Del Cauca
Biomelab S A S, Barranquilla, Not set
Clinica Colsanitas S.A. - Sede Clinica Universitaria Colombia, Bogota, Not set
Rodrigo Botero SAS, Medellin, Not set
Fundacion Colombiana de Cancerologia Clinica Vida, Medellin, Not set
Oncomedica S.A., Monteria, Not set
Institut Bergonie, Bordeaux, Not set
Centre de Lutte Contre le Cancer Francois Baclesse, Caen, Not set
Centre Oscar Lambret, Lille, Not set
Centre Leon Berard, Lyon, Not set
Institut Regional du Cancer de Montpellier - ICM, Montpellier, Not set
Hopital prive du Confluent, Nantes, Not set
Groupe Hospitalier Broca Cochin Hotel Dieu, Paris, Not set
Hopital Diaconesses Croix Saint Simon, Paris, Not set
Centre Hospitalier Lyon Sud, Pierre Benite, Not set
Centre Armoricain de Radiotherapie Imagerie medicale et Oncologie, Plerin, Not set
Centre Eugene Marquis, Rennes, Not set
Institut Gustave Roussy, Villejuif, Not set
EISAI Trial Site 4, Berlin, Not set
EISAI Trial Site 2, Dresden, Not set
EISAI Trial Site 1, Erlangen, Not set
EISAI Trial Site 6, Hamburg, Not set
EISAI Trial Site 3, Rostock, Not set
EISAI Trial Site 5, Tuebingen, Not set
Mater Misericordiae University Hospital, Dublin, Not set
Soroka Medical Center, Beer Sheva, Not set
Rambam Medical Center, Haifa, Not set
Edith Wolfson Medical Center, Holon, Not set
Hadassah Medical Center. Ein Kerem, Jerusalem, Not set
Rabin Medical Center, Petah Tikva, Not set
Chaim Sheba Medical Center, Ramat Gan, Not set
Azienda Ospedaliera per l Emergenza Cannizzaro, Catania, Not set
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, Not set
Ospedale San Raffaele, Milano, Not set
Istituto Europeo di Oncologia, Milano, Not set
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Not set
Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Not set
Policlinico Universitario Agostino Gemelli, Roma, Not set
EISAI Trial Site 9, Nagoya, Aichi
EISAI Trial Site 18, Kashiwa, Chiba
EISAI Trial Site 7, Matsuyama, Ehime
EISAI Trial Site 15, Toon, Ehime
EISAI Trial Site 5, Kurume, Fukoka
EISAI Trial Site 11, Sapporo, Hokkaido
EISAI Trial Site 8, Akashi, Hyogo
EISAI Trial Site 17, Tsukuba, Ibaraki
EISAI Trial Site 4, Morioka, Iwate
EISAI Trial Site 19, Isehara, Kanagawa
EISAI Trial Site 14, Sendai, Miyagi
EISAI Trial Site 1, Hidaka, Saitama
EISAI Trial Site 2, Sunto-gun, Shizuoka
EISAI Trial Site 16, Kagoshima, Not set
EISAI Trial Site 3, Niigata, Not set
EISAI Trial Site 10, Tokyo, Not set
EISAI Trial Site 12, Tokyo, Not set
EISAI Trial Site 13, Tokyo, Not set
EISAI Trial Site 6, Tokyo, Not set
National Cancer Center, Goyang-si, Gyeonggi-do
Seoul National University Hospital, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Investigacion Onco Farmaceutica S de RL de CV, La Paz, Baja California
Alivia Clinica de Alta Especialidad S.A. de C.V., Monterrey, Nuevo Leon
Grupo Medico Camino SC, Mexico City, Not set
Centro Hemato Oncologico Privado, Toluca, Not set
Faicic S de RL de CV, Veracruz, Not set
Auckland City Hospital, Auckland, Not set
Centrum Onkologii Instytut im. Marii Sklodowskiej Curie, Krakow, Malopolskie
Centrum Onkologii. Instytut im. Marii Sklodowskiej-Curie, Warszawa, Mazowieckie
Beskidzkie Centrum Onkologii im. Jana Pawla II, Bielsko-Biala, Not set
Szpital Morski im. PCK Szpitale Wojewodzkie w Gdyni Sp. z o.o., Gdynia, Not set
Centrum Onkologii Instytut im. Marii Sklodowskiej Curie, Gliwice, Not set
Instytut Centrum Zdrowia Matki Polki, Lodz, Not set
Pomorski Uniwersytet Medyczny w Szczecinie, Szczecin, Not set
Szpital Kliniczny im Ks Anny Mazowieckiej, Warszawa, Not set
Altay Regional Oncology Dispensary, Barnaul, Not set
Republican Clinical Oncology Dispensary of Tatarstan MoH, Kazan, Not set
FSBI National Medical Oncology Research Center n.a. N.N. Blokhina, Moscow, Not set
FSBI-FRCC of Special Types Med. Care & Technologies FMBA of Russia, Moscow, Not set
SPb SBHI City Clinical Oncological Dispensary, Saint Petersburg, Not set
Leningrad Regional Oncology Center, Saint-Petersburg, Not set
Mordovia Republican Oncological Dispensary, Saransk, Not set
Tomsk National Research Medical Center of Russian Academy of Sciences, Tomsk, Not set
Republican Clinical Oncology Dispensary of Republic of Bashkortostan, Ufa, Not set
Instituto Catalan de Oncologia ICO - Hospital Duran i Reynals, Hospitalet de Llobregat, Barcelona
Hospital General Universitari Vall d Hebron, Barcelona, Not set
Hospital Universitario Gregorio Maranon, Madrid, Not set
Clinica Universitaria Navarra - Madrid, Madrid, Not set
Hospital Ramon y Cajal, Madrid, Not set
Hospital Clinico San Carlos, Madrid, Not set
Hospital Universitario y Politecnico La Fe de Valencia, Valencia, Not set
Taipei Veterans General Hospital, Taipei, Beitou
Kaohsiung Veterans General Hospital, Kaohsiung, Not set
Kaohsiung Chang Gung Memorial Hospital of the C.G.M.F., Kaohsiung, Not set
Taichung Veterans General Hospital, Taichung, Not set
National Taiwan University Hospital, Taipei, Not set
Chang Gung Medical Foundation. Linkou Branch, Taoyuan, Not set
Basken Adana Dr.Turgut Noyan Uygulama ve Arastirma Merkezi, Adana, Not set
Hacettepe University Medical Faculty, Ankara, Not set
Baskent Universitesi Ankara Hastanesi, Ankara, Not set
Acibadem Bursa Hastanesi, Bursa, Not set
Acibadem Universitesi Atakent Hastanesi, Istanbul, Not set
Florence Nightingale Gayrettepe Hastanesi, Istanbul, Not set
Ege Universitesi Tip Fakultesi, Izmir, Not set
Royal Sussex County Hospital, Brighton, Not set
Addenbrookes Hospital, Cambridge, Not set
Barts Health NHS Trust - St Bartholomew s Hospital, London, Not set
Guy s & St Thomas NHS Foundation Trust, London, Not set
The Royal Marsden Foundation Trust, London, Not set
The Royal Marsden NHS Foundation Trust, London, Not set
Imperial College Healthcare NHS Trust, London, Not set
University College Hospital, London, Not set
University Hospital Southampton NHS Foundation Trust, Southampton, Not set
Conditions: Endometrial Neoplasms
Capivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBC
Active Not Recruiting
Phase III Study of Capivasertib + Paclitaxel versus Placebo + Paclitaxel as First line Treatment for Patients with Locally Advanced or Metastatic Triple-negative Breast Cancer (TNBC)
Phase III Study of Capivasertib + Paclitaxel versus Placebo + Paclitaxel as First line Treatment for Patients with Locally Advanced or Metastatic Triple-negative Breast Cancer (TNBC) Read Less
Gender:
ALL
Ages:
Between 18 years and 130 years
Trial Updated:
05/15/2025
Locations: Research Site, Whittier, California +259 locations
Research Site, Whittier, California
Research Site, Whittier, California
Research Site, Fort Myers, Florida
Research Site, Miami, Florida
Research Site, Saint Petersburg, Florida
Research Site, Tampa, Florida
Research Site, Chicago, Illinois
Research Site, Westwood, Kansas
Research Site, Silver Spring, Maryland
Research Site, Detroit, Michigan
Research Site, Nyack, New York
Research Site, Cincinnati, Ohio
Research Site, Columbus, Ohio
Research Site, Harrisburg, Pennsylvania
Research Site, Philadelphia, Pennsylvania
Research Site, Pittsburgh, Pennsylvania
Research Site, Nashville, Tennessee
Research Site, Austin, Texas
Research Site, Fort Worth, Texas
Research Site, Houston, Texas
Research Site, San Antonio, Texas
Research Site, Fairfax, Virginia
Research Site, Buenos Aires, Not set
Research Site, Caba, Not set
Research Site, Caba, Not set
Research Site, Caba, Not set
Research Site, Caba, Not set
Research Site, Ciudad Autonomade Buenos Aires, Not set
Research Site, La Plata, Not set
Research Site, Mar del Plata, Not set
Research Site, Rosario, Not set
Research Site, Barretos, Not set
Research Site, Florianópolis, Not set
Research Site, Goiania, Not set
Research Site, Londrina, Not set
Research Site, Natal, Not set
Research Site, Porto Alegre, Not set
Research Site, Porto Alegre, Not set
Research Site, Rio de Janeiro, Not set
Research Site, Sao Paulo, Not set
Research Site, Sao Paulo, Not set
Research Site, São José do Rio Preto, Not set
Research Site, São Paulo, Not set
Research Site, Victoria, British Columbia
Research Site, Kitchener, Ontario
Research Site, North York, Ontario
Research Site, Toronto, Ontario
Research Site, Beijing, Not set
Research Site, Beijing, Not set
Research Site, Changchun, Not set
Research Site, Changsha, Not set
Research Site, Changsha, Not set
Research Site, Chengdu, Not set
Research Site, Chengdu, Not set
Research Site, Foshan, Not set
Research Site, Guangzhou, Not set
Research Site, Guiyang, Not set
Research Site, Haikou, Not set
Research Site, Hangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Harbin, Not set
Research Site, Hefei, Not set
Research Site, Jinan, Not set
Research Site, Linyi, Not set
Research Site, Nanchang, Not set
Research Site, Nanjing, Not set
Research Site, Nanyang, Not set
Research Site, Shanghai, Not set
Research Site, Shenyang, Not set
Research Site, Shenyang, Not set
Research Site, Urumqi, Not set
Research Site, Wenzhou, Not set
Research Site, Wuhan, Not set
Research Site, Wuhan, Not set
Research Site, Xi'an, Not set
Research Site, Zhengzhou, Not set
Research Site, Floridablanca, Not set
Research Site, Ibague, Not set
Research Site, Medellin, Not set
Research Site, Monteria, Not set
Research Site, Valledupar, Not set
Research Site, Hradec Kralove, Not set
Research Site, Olomouc, Not set
Research Site, Praha 10, Not set
Research Site, Praha 2, Not set
Research Site, Brest Cedex, Not set
Research Site, Lyon, Not set
Research Site, Marseille, Not set
Research Site, Montpellier, Not set
Research Site, Nice, Not set
Research Site, Paris, Not set
Research Site, Saint Herblain, Not set
Research Site, Villejuif, Not set
Research Site, Athens, Not set
Research Site, Athens, Not set
Research Site, Athens, Not set
Research Site, Heraklion, Not set
Research Site, Thessaloniki, Not set
Research Site, Budapest, Not set
Research Site, Budapest, Not set
Research Site, Budapest, Not set
Research Site, Győr, Not set
Research Site, Nyíregyháza, Not set
Research Site, Szekszárd, Not set
Research Site, Bangalore, Not set
Research Site, Bangalore, Not set
Research Site, Gurgaon, Not set
Research Site, Kolkata, Not set
Research Site, Kolkata, Not set
Research Site, Mumbai, Not set
Research Site, Mysuru, Not set
Research Site, Nagpur, Not set
Research Site, Nagpur, Not set
Research Site, Nashik, Not set
Research Site, New Delhi, Not set
Research Site, New Delhi, Not set
Research Site, Bunkyo-ku, Not set
Research Site, Fukuoka-shi, Not set
Research Site, Hidaka-shi, Not set
Research Site, Hiroshima-shi, Not set
Research Site, Kagoshima-shi, Not set
Research Site, Kitaadachi-gun, Not set
Research Site, Koto-ku, Not set
Research Site, Kumamoto-shi, Not set
Research Site, Matsuyama-shi, Not set
Research Site, Nagoya-shi, Not set
Research Site, Niigata-shi, Not set
Research Site, Osaka-shi, Not set
Research Site, Osaka-shi, Not set
Research Site, Ota-shi, Not set
Research Site, Sapporo-shi, Not set
Research Site, Sendai-shi, Not set
Research Site, Shinagawa-ku, Not set
Research Site, Shinjuku-ku, Not set
Research Site, Sunto-gun, Not set
Research Site, Takasaki-shi, Not set
Research Site, Tsu-shi, Not set
Research Site, Tsukuba-shi, Not set
Research Site, Yokohama-shi, Not set
Research Site, Busan-si, Not set
Research Site, Cheonan-si, Not set
Research Site, Cheongju-si, Not set
Research Site, Daegu, Not set
Research Site, Goyang-si, Not set
Research Site, Incheon, Not set
Research Site, Seongnam-si, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Kuala Lumpur, Not set
Research Site, Kuala Lumpur, Not set
Research Site, Kuching, Not set
Research Site, Selangor, Not set
Research Site, Aguascalientes, Not set
Research Site, Estado de México, Not set
Research Site, Guadalajara, Not set
Research Site, Mexico, Not set
Research Site, Monterrey, Not set
Research Site, Tuxtla Gutierrez, Not set
Research Site, Tuxtla Gutierrez, Not set
Research Site, Arequipa, Not set
Research Site, Callao, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Bacolod, Not set
Research Site, Baguio City, Not set
Research Site, Cagayan De Oro City, Not set
Research Site, Cebu City, Not set
Research Site, Davao City, Not set
Research Site, Iloilo City, Not set
Research Site, Iloilo, Not set
Research Site, Las Pinas, Not set
Research Site, Legazpi City, Not set
Research Site, Manila, Not set
Research Site, Quezon City, Not set
Research Site, San Juan, Not set
Research Site, Bydgoszcz, Not set
Research Site, Konin, Not set
Research Site, Poznan, Not set
Research Site, Racibórz, Not set
Research Site, Radom, Not set
Research Site, Tomaszów Mazowiecki, Not set
Research Site, Warszawa, Not set
Research Site, Wroclaw, Not set
Research Site, Lisboa, Not set
Research Site, Lisboa, Not set
Research Site, Lisboa, Not set
Research Site, Porto, Not set
Research Site, Arkhangelsk, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Saint-Petersburg, Not set
Research Site, Saint-Petersburg, Not set
Research Site, Volgograd, Not set
Research Site, Yaroslavl, Not set
Research Site, Dammam, Not set
Research Site, Jeddah, Not set
Research Site, Makkah, Not set
Research Site, Riyadh, Not set
Research Site, Riyadh, Not set
Research Site, Riyadh, Not set
Research Site, Riyadh, Not set
Research Site, Bratislava, Not set
Research Site, Johannesburg, Not set
Research Site, Johannesburg, Not set
Research Site, Pretoria, Not set
Research Site, Pretoria, Not set
Research Site, Badalona, Not set
Research Site, Barcelona, Not set
Research Site, Barcelona, Not set
Research Site, Hospitalet deLlobregat, Not set
Research Site, Jaén, Not set
Research Site, Madrid, Not set
Research Site, Málaga, Not set
Research Site, Sevilla, Not set
Research Site, Valencia, Not set
Research Site, Zaragoza, Not set
Research Site, Göteborg, Not set
Research Site, Lund, Not set
Research Site, Stockholm, Not set
Research Site, Hsinchu, Not set
Research Site, Hualien City, Not set
Research Site, Kaohsiung, Not set
Research Site, Kaohsiung, Not set
Research Site, Tainan City, Not set
Research Site, Tainan, Not set
Research Site, Taipei City, Not set
Research Site, Taipei City, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Bangkok, Not set
Research Site, Bangkok, Not set
Research Site, Bangkok, Not set
Research Site, Bangkok, Not set
Research Site, Hat Yai, Not set
Research Site, Mueang, Not set
Research Site, Ankara, Not set
Research Site, Ankara, Not set
Research Site, Istanbul, Not set
Research Site, Izmir, Not set
Research Site, Malatya, Not set
Research Site, Mersin, Not set
Research Site, Edinburgh, Not set
Research Site, London, Not set
Research Site, London, Not set
Research Site, London, Not set
Research Site, Sheffield, Not set
Research Site, Surrey, Not set
Research Site, York, Not set
Research Site, Hanoi, Not set
Research Site, Ho Chi Minh city, Not set
Research Site, Ho Chi Minh, Not set
Conditions: Triple Negative Breast Neoplasms
Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Patients With Previously Untreated Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer
Recruiting
The primary objective of this study is to compare the progression-free survival (PFS) between sacituzumab govitecan-hziy (SG) versus treatment of physician's choice (TPC) in participants with previously untreated, locally advanced, inoperable or metastatic triple-negative breast cancer whose tumors do not express programmed cell death ligand 1 (PD-L1) or in participants previously treated with anti-programmed cell death (ligand or protein) 1 (Anti-PD-(L)1) Agents in the early setting whose tumor... Read More
The primary objective of this study is to compare the progression-free survival (PFS) between sacituzumab govitecan-hziy (SG) versus treatment of physician's choice (TPC) in participants with previously untreated, locally advanced, inoperable or metastatic triple-negative breast cancer whose tumors do not express programmed cell death ligand 1 (PD-L1) or in participants previously treated with anti-programmed cell death (ligand or protein) 1 (Anti-PD-(L)1) Agents in the early setting whose tumors do express PD-L1. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/15/2025
Locations: Alaska Oncology and Hematology, Anchorage, Alaska +515 locations
Alaska Oncology and Hematology, Anchorage, Alaska
Arizona Oncology Associates, PC-Hope,1845 W Orange Grove Rd, Tucson, Arizona
Arizona Oncology Associates, PC-Hope,2070 W. Rudasill Rd., Tucson, Arizona
Arizona Oncology Associates, PC-Hope, Tucson, Arizona
Arizona Oncology Associates, PC-Hope,1620 West St. Mary's Road, Tucson, Arizona
Genesis Cancer and Blood Institute,1455 Higdon Ferry Road Suite B., Hot Springs, Arkansas
Genesis Cancer and Blood Institute, Hot Springs, Arkansas
Saint Bernards Medical Center, Jonesboro, Arkansas
Saint Bernards Medical Center,4000 Linwood Drive, Paragould, Arkansas
University of California Los Angeles - Jonsson Comprehensive Cancer Center,201 S. Buena Vista Street, Suite 200, Burbank, California
University of California San Diego Moores Cancer, La Jolla, California
University of California Los Angeles - Jonsson Comprehensive Cancer Center,24302 Paseo de Valencia, Suite 200, Laguna Hills, California
Cancer and Blood Specialty Clinic, Los Alamitos, California
University of California Los Angeles - Jonsson Comprehensive Cancer Center,892 Aerovista Place, Suite 240, San Luis Obispo, California
Sansum Clinic, Santa Barbara, California
University of California Los Angeles - Jonsson Comprehensive Cancer Center,2020 Santa Monica Blvd, Suite 600, Santa Monica, California
University of California Los Angeles - Jonsson Comprehensive Cancer Center,2336 Santa Monica, Suites 302 and 304, Santa Monica, California
University of California Los Angeles - Jonsson Comprehensive Cancer Center, Santa Monica, California
Sansum Clinic,2040 Viborg Road, Solvang, California
Torrance Memorial Physician Network - Cancer Care, Torrance, California
University of California Los Angeles - Jonsson Comprehensive Cancer Center,1250 La Venta Dr, Suite 100, Westlake Village, California
Rocky Mountain Cancer Centers,1700 South Potomac Street, Aurora, Colorado
Rocky Mountain Cancer Centers, Boulder, Colorado
Rocky Mountain Cancer Centers,2312 N. Nevada Avenue, Colorado Springs, Colorado
Rocky Mountain Cancer Centers,6031 E. Woodman Rd., Colorado Springs, Colorado
Rocky Mountain Cancer Centers,4700 E. Hale Parkway, Denver, Colorado
Rocky Mountain Cancer Centers,11750 West 2nd Place, Lakewood, Colorado
Rocky Mountain Cancer Centers,22 West Dry Creek Circle, Littleton, Colorado
Rocky Mountain Cancer Centers,10107 Ridge Gate Parkway, Lone Tree, Colorado
Rocky Mountain Cancer Centers,2030 Mountain View Ave Ste 210, Longmont, Colorado
Rocky Mountain Cancer Centers,3676 Parker Blvd, Pueblo, Colorado
Rocky Mountain Cancer Centers,525 W. 15th Street, Pueblo, Colorado
Rocky Mountain Cancer Centers,8820 Huron Street, Thornton, Colorado
Eastern Connecticut Hematology and Oncology Associates, Norwich, Connecticut
AdventHealth Medical Group, Altamonte Springs, Florida
Florida Cancer Specialists - North Region Research Office,750 Orienta Ave, Altamonte Springs, Florida
Florida Cancer Specialists,9776 Bonita Beach Road Southeast Suite 201 A, Bonita Springs, Florida
Florida Cancer Specialists,3630 Manatee Avenue West, Bradenton, Florida
Florida Cancer Specialists,5985 Silver Falls Run, Bradenton, Florida
Florida Cancer Specialists - North Region Research Office,403 S. Kings Ave., Brandon, Florida
Florida Cancer Specialists,1030 Commerce Creek Blvd, Cape Coral, Florida
Florida Cancer Specialists - North Region Research Office,3280 McMullen Booth Road, Clearwater, Florida
Florida Cancer Specialists - West Palm Beach,224 Memorial Medical Parkway, Suite 300, Daytona Beach, Florida
Holy Cross Hospital, Inc, Fort Lauderdale, Florida
Florida Cancer Specialists, Fort Myers, Florida
Florida Cancer Specialists,8981 Colonial Center Drive, Fort Myers, Florida
Florida Cancer Specialists,8260 Gladiolus Dr, Fort Myers, Florida
Florida Cancer Specialists - North Region Research Office,6420 W. Newberry Road, Gainesville, Florida
Florida Cancer Specialists - North Region Research Office,100 Highland Avenue, Largo, Florida
Florida Cancer Specialists - North Region Research Office,521 North Lecanto Highway, Lecanto, Florida
Florida Cancer Specialists,1100 Goodlette Road, Naples, Florida
Florida Cancer Specialists,681 4th Avenue North, Naples, Florida
Florida Cancer Specialists - North Region Research Office,4945 SW 49th Place, Ocala, Florida
Florida Cancer Specialists - North Region Research Office,2824 Enterprise Rd, Orange City, Florida
AdventHealth Medical Group,2501 North Orange Ave, Orlando, Florida
Florida Cancer Specialists - North Region Research Office,70 W. Gore Street, Orlando, Florida
Sacred Heart Heatlh System, Inc., d/b/a Ascension Sacred Heart, Pensacola, Florida
Florida Cancer Specialists,22395 Edgewater Drive, Port Charlotte, Florida
Florida Cancer Specialists - North Region Research Office,1201 Fifth Avenue North, Saint Petersburg, Florida
Florida Cancer Specialists - North Region Research Office, Saint Petersburg, Florida
Sacred Heart Heatlh System, Inc., d/b/a Ascension Sacred Heart,27 Mack Bayou Loop, Santa Rosa Beach, Florida
Florida Cancer Specialists,600 North Cattlemen Road, Sarasota, Florida
Florida Cancer Specialists,1970 Golf Street, Sarasota, Florida
Florida Cancer Specialists - North Region Research Office,7154 Medical Center Drive, Spring Hill, Florida
Florida Cancer Specialists - West Palm Beach,301 SE Ocean Blvd, Suite 102, Stuart, Florida
Florida Cancer Specialists - North Region Research Office,3402 West Dr. Martin Luther King Jr. Boulevard, Tampa, Florida
Florida Cancer Specialists - North Region Research Office,4100 Waterman Way, Tavares, Florida
Florida Cancer Specialists - North Region Research Office,1400 US Highway 441 N, The Villages, Florida
Florida Cancer Specialists - North Region Research Office,9320 State Road 54, Trinity, Florida
Florida Cancer Specialists,901 South Tamiami Trail, Venice, Florida
Florida Cancer Specialists,836 Sunset Lake Blvd, Venice, Florida
Florida Cancer Specialists - West Palm Beach,3730 7th Terrace, Suite 101, Vero Beach, Florida
Florida Cancer Specialists - West Palm Beach,1037 S. State Road 7, Bldg B, Suite 303, Wellington, Florida
Florida Cancer Specialists - West Palm Beach, West Palm Beach, Florida
Florida Cancer Specialists - North Region Research Office,460 N Orlando Ave, Winter Park, Florida
Northside Hospital,125 King Avenue, Athens, Georgia
Piedmont Cancer Institute - Atlanta,1267 Hwy 54W, Atlanta, Georgia
Piedmont Cancer Institute - Atlanta, Atlanta, Georgia
Northside Hospital,5670 Peachtree Dunwoody Rd., Atlanta, Georgia
Northside Hospital, Atlanta, Georgia
Northside Hospital,308 Deep South Farm Rd, Suite 200, Blairsville, Georgia
Northside Hospital,228 Riverstone Dr., Canton, Georgia
Northwest Georgia Oncology Northwest Georgia Oncology Centers, PCCenters, PC,157 Clinic Avenue, Carrollton, Georgia
Northwest Georgia Oncology Northwest Georgia Oncology Centers, PCCenters, PC,100 Market Place Blvd, Cartersville, Georgia
Northside Hospital,1505 Northside Blvd, Suite 4600, Cumming, Georgia
Northside Hospital,3855 Pleasant Hill Rd., Suite 480, Duluth, Georgia
Northside Hospital,308 Coliseum Dr., Macon, Georgia
Northwest Georgia Oncology Northwest Georgia Oncology Centers, PCCenters, PC, Marietta, Georgia
Piedmont Cancer Institute - Atlanta,775 Poplar Road, Newnan, Georgia
Piedmont Cancer Institute - Atlanta,1240 Eagles Landing Pkwy, Stockbridge, Georgia
Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois
Rush University Medical Center, Chicago, Illinois
University of Illinois Hospital and Health Sciences System (Outpatient Cancer Center), Chicago, Illinois
Orchard Healthcare Research Inc,2845 North Sheridan Road, 1st Floor, Chicago, Illinois
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,1 Kish Hospital Drive, DeKalb, Illinois
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,10 Health Services Drive, DeKalb, Illinois
Orchard Healthcare Research Inc,800 Austin Street, Suite 360, East Tower, Evanston, Illinois
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,300 Randall Road, Geneva, Illinois
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,304 Randall Road, Geneva, Illinois
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,1000 N. Westmoreland Road, Lake Forest, Illinois
Rush University Medical Center,520 South Maple Ave, Oak Park, Illinois
Orchard Healthcare Research Inc, Skokie, Illinois
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,4405 Weaver Parkway, Warrenville, Illinois
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,4455 Weaver Parkway, Warrenville, Illinois
Robert H. Lurie Comprehensive Cancer Center of Northwestern University,25 N Winfield Road, Winfield, Illinois
Fort Wayne Medical Oncology and Hematology - Fort, Fort Wayne, Indiana
University of Iowa Hospitals and Clinics, Iowa City, Iowa
The University of Kansas Cancer Center,2000 Olathe Blvd, Kansas City, Kansas
The University of Kansas Cancer Center,12200 W. 110th Street, Overland Park, Kansas
The University of Kansas Cancer Center,10710 Nall Avenue, Overland Park, Kansas
The University of Kansas Cancer Center,10730 Nall Avenue, Overland Park, Kansas
The University of Kansas Cancer Center, Westwood, Kansas
Norton Cancer Institute - Saint Matthews,234 E. Gray Strret, Louisville, Kentucky
Norton Cancer Institute - Saint Matthews,676 S. Floyd Street, Louisville, Kentucky
Norton Cancer Institute - Saint Matthews, Louisville, Kentucky
Norton Cancer Institute - Saint Matthews,4955 Norton Healthcare Blvd, Louisville, Kentucky
Hematology Oncology Clinic - Baton Rouge, Baton Rouge, Louisiana
Hematology Oncology Clinic - Baton Rouge,1673 E Mount Please Drive, Zachary, Louisiana
Mercy Medical Center, Baltimore, Maryland
Cancer Institute Ascension Saint Agnes, Baltimore, Maryland
Beth Israel Deaconess Medical Center, Boston, Massachusetts
Dana-Farber Cancer Institute, Boston, Massachusetts
Massachusetts General Hospital, Boston, Massachusetts
Massachusetts General Hospital,102 Endicott Street, Danvers, Massachusetts
Massachusetts General Hospital,2014 Washington St, Newton, Massachusetts
University of Michigan, Ann Arbor, Michigan
Ascension St. John Hospital, Grosse Pointe Woods, Michigan
Ascension Providence Hospital, Southfield, Michigan
The West Clinic, PLLC dba West Cancer Center,7668 Airways Blvd, Southaven, Mississippi
The University of Kansas Cancer Center,2750 Clay Edwards Drive, Kansas City, Missouri
The University of Kansas Cancer Center,8700 North Green Hills Road, Kansas City, Missouri
The University of Kansas Cancer Center,4881 N.E. Goodview Circle, Lee's Summit, Missouri
Nebraska Cancer Specialists,2730 W. Faidley Ave, Grand Island, Nebraska
Nebraska Cancer Specialists,8303 Dodge Street, Omaha, Nebraska
Nebraska Cancer Specialists, Omaha, Nebraska
Nebraska Cancer Specialists,611 Fenwick Dr, Papillion, Nebraska
Summit Medical Group Eastside Clinic,1 Diamond Hill Road, Berkeley Heights, New Jersey
Summit Medical Group Eastside Clinic, Florham Park, New Jersey
Rutgers Cancer Institute of New Jersey,414 Grand Street, Jersey City, New Jersey
Rutgers Cancer Institute of New Jersey,600 River Avenue, Lakewood, New Jersey
Rutgers Cancer Institute of New Jersey,94 Old Short Hills Road, Livingston, New Jersey
Rutgers Cancer Institute of New Jersey,300 Second Ave, Long Branch, New Jersey
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
Rutgers Cancer Institute of New Jersey,150 Bergen St., Newark, New Jersey
Rutgers Cancer Institute of New Jersey,201 Lyons Avenue, Newark, New Jersey
Capital Health Medical Center - Hopewell, Pennington, New Jersey
Rutgers Cancer Institute of New Jersey,110 Rehill Ave, Somerville, New Jersey
Rutgers Cancer Institute of New Jersey,99 Highway 37 West, Toms River, New Jersey
Rutgers Cancer Institute of New Jersey,100 State Route 36, West Long Branch, New Jersey
New York Cancer & Blood Specialists - Port Jeffers,72 East Main St., Babylon, New York
New York Cancer & Blood Specialists - Port Jeffers,12 East 86th St, Suite 4, Bronx, New York
Montefiore Medical Center - Montefiore Medical Park, Bronx, New York
New York Cancer & Blood Specialists - Port Jeffers,2330 Eastchester Road, Suite 360, Bronx, New York
Hematology Oncology Associates of Central New York, East Syracuse, New York
Queens Hospital Center, Jamaica, New York
New York Cancer & Blood Specialists - Port Jeffers,1 Delaware Dr., New Hyde Park, New York
NYP/Columbia Univeresity Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York
New York Cancer & Blood Specialists - Port Jeffers,365 East Main St., Patchogue, New York
New York Cancer & Blood Specialists - Port Jeffers,49 Rte. 347, Newconset Hwy, Port Jefferson Station, New York
New York Cancer & Blood Specialists - Port Jeffers, Port Jefferson Station, New York
New York Cancer & Blood Specialists - Port Jeffers,1500 Rte, 112, Building 4, Port Jefferson, New York
New York Cancer & Blood Specialists - Port Jeffers,750 Old County Rd. Suite 4, Riverhead, New York
Novant Health Cancer Institute - Forsyth,125 Queens Road, Suite 650, Charlotte, North Carolina
Novant Health Cancer Institute - Forsyth,2131 S. 17th Street, Wilmington, North Carolina
Novant Health Cancer Institute - Forsyth, Winston-Salem, North Carolina
Zangmeister Cancer Center, Columbus, Ohio
Northwest Cancer Specialists, P.C,5050 NE Hoyt St., Portland, Oregon
Northwest Cancer Specialists, P.C,265 N. Broadway, Portland, Oregon
Northwest Cancer Specialists, P.C, Tigard, Oregon
Magee-Womens Hospital of UPMC,2500 West 12th Street, Erie, Pennsylvania
Magee-Womens Hospital of UPMC,201 State Street, 6 Main, Erie, Pennsylvania
Magee-Womens Hospital of UPMC,4300 Londonberry Road, Harrisburg, Pennsylvania
Magee-Womens Hospital of UPMC,2035 Technology Parkway, Mechanicsburg, Pennsylvania
University of Pennsylvania Abramson Cancer Center, Philadelphia, Pennsylvania
Magee-Womens Hospital of UPMC, Pittsburgh, Pennsylvania
Magee-Womens Hospital of UPMC,5115 Centre Avenue, Pittsburgh, Pennsylvania
Magee-Womens Hospital of UPMC,1703 Innovation Drive, York, Pennsylvania
Tennessee Oncology, PLLC,103 Natchez Park Drive, Dickson, Tennessee
Tennessee Oncology, PLLC,4488 Carothers Parkway, Franklin, Tennessee
Tennessee Oncology, PLLC,225 Big Station Camp Blvd, Gallatin, Tennessee
The West Clinic, PLLC dba West Cancer Center, Germantown, Tennessee
Tennessee Oncology, PLLC,353 New Shackle Island Road, Hendersonville, Tennessee
Tennessee Oncology, PLLC,5653 First Blvd., Hermitage, Tennessee
Tennessee Oncology, PLLC,103 Physicians Way, Lebanon, Tennessee
Tennessee Oncology, PLLC,1840 Medical Center Parkway, Murfreesboro, Tennessee
Tennessee Oncology, PLLC,2004 Hayes Street, Nashville, Tennessee
Tennessee Oncology, PLLC,SCRI Oncology Partners, Nashville, Tennessee
Tennessee Oncology, PLLC, Nashville, Tennessee
Tennessee Oncology, PLLC,4220 Harding Rd, Nashville, Tennessee
Tennessee Oncology, PLLC,3443 Dickerson Road, Nashville, Tennessee
Tennessee Oncology, PLLC,397 Wallace Road, Nashville, Tennessee
Tennessee Oncology, PLLC,120 Frank Martin Road, Shelbyville, Tennessee
Tennessee Oncology, PLLC,300 Stonecrest Blvd, Smyrna, Tennessee
The Center for Cancer & Blood Disorders - Magnolia,515 W. Mayfield Rd., Arlington, Texas
Texas Oncology PA,901 West 38th Street, Austin, Texas
Texas Oncology PA, Austin, Texas
Texas Oncology PA,4101 James Casey, Suite 100, Austin, Texas
The Center for Cancer & Blood Disorders - Magnolia,11805 South Freeway, Burleson, Texas
Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas, Texas
Texas Oncology-Denison, Denison, Texas
The Center for Cancer & Blood Disorders - Magnolia, Fort Worth, Texas
Oncology Consultants,1631 North Loop West, Houston, Texas
Oncology Consultants,925 Gessner, Houston, Texas
Oncology Consultants, Houston, Texas
Mays Cancer Center, San Antonio, Texas
The Center for Cancer & Blood Disorders - Magnolia,920 Santa Fe Drive, Weatherford, Texas
Virginia Oncology Associates,744 N. Battlefield Blvd, Chesapeake, Virginia
Virginia Cancer Specialists, PC,7501 Right Flank Road, Mechanicsville, Virginia
Virginia Oncology Associates,1051 Loftis Blvd Suite 100, Newport News, Virginia
Virginia Oncology Associates, Norfolk, Virginia
Virginia Cancer Specialists, PC,210 Medical Park Boulevard, Petersburg, Virginia
Virginia Cancer Specialists, PC,1401 Johnston-Willis Drive, Richmond, Virginia
Virginia Cancer Specialists, PC, Richmond, Virginia
Virginia Oncology Associates,1950 Glenn Mitchell Drive, Virginia Beach, Virginia
Swedish Cancer Institute-First Hill,21632 Highway 99, Edmonds, Washington
Swedish Cancer Institute-First Hill,751 NE Blakely Drive, Issaquah, Washington
Swedish Cancer Institute-First Hill, Seattle, Washington
Swedish Cancer Institute-First Hill,747 Broadway, Seattle, Washington
Northwest Cancer Specialists, P.C,210 SE 136th Avenue, Vancouver, Washington
Hospital Británico de Buenos Aires, Buenos Aires, Not set
Instituto de Oncologia Angel H.Roffo, Caba, Not set
Fundacion CORI para la Investigacion y Prevencion del Cancer, Capital, Not set
Instituto de Oncología de Rosario, Rosario, Not set
Centro para la Atencion Integral del Paciente Oncologico Centro Médico C.A.I.P.O, San Miguel de Tucumán, Not set
Clinica Viedma, Viedma, Not set
Border Medical Oncology, Albury, New South Wales
Saint George Hospital - Australia, Kogarah, New South Wales
Mater Hospital - North Sydney, North Sydney, New South Wales
GenesisCare - North Shore, St Leonards, New South Wales
Mater Misericordiae Limited and Mater Research Limited, South Brisbane, Queensland
Princess Alexandra Hospital, Woolloongabba, Queensland
Cancer Research SA (CRSA), Adelaide, South Australia
Icon Cancer Centre Hobart, Hobart, Tasmania
Monash Medical Centre, Clayton, Victoria
Austin Hospital, Melbourne, Victoria
Breast Cancer Research Center - Western Australia, Nedlands, Western Australia
Universitätsklinikum Graz, Graz, Not set
Medizinische Universität Innsbruck, Innsbruck, Not set
Ordensklinikum Linz GmbH Barmherzige Schwestern, Linz, Not set
Landeskrankenhaus Salzburg, Salzburg, Not set
Universitätsklinikum Sankt Pölten, Sankt Poelten, Not set
Landesklinikum Wiener Neustadt, Wiener Neustadt, Not set
Medizinische Universität Wien, Wien, Not set
Algemeen Ziekenhuis Klina, Brasschaat, Not set
Cliniques Universitaires Saint-Luc, Brussels, Not set
Universitair Ziekenhuis Brussel, Brussels, Not set
Grand Hopital de Charleroi - Notre Dame, Charleroi, Not set
Universitair Ziekenhuis Gent, Gent, Not set
UZ Leuven, Leuven, Not set
Centre Hospitalier Universitaire Université Cathol, Namur, Not set
Hospital Araújo Jorge - Associação de Combate ao Câncer em Goiás - ACCG, Goiânia, Not set
ONCOSITE - Centro de Pesquisa Clinica em Oncologia, Ijui, Not set
Catarina Pesquisa Clínica, Itajai, Not set
Hospital Moinhos de Vento, Porto Alegre, Not set
Hospital de Clinicas de Porto Alegre - HCPA, Porto Alegre, Not set
Hospital Sao Lucas da PUCRS, Porto Alegre, Not set
Instituto Nacional de Câncer - INCA - HCIII, Rio de Janeiro, Not set
Núcleo de Oncologia da Bahia, Salvador, Not set
CEPHO - Centro de Estudos e PesquisaS de Hematologia e Oncologia, Santo Andre, Not set
Hospital Amaral Carvalho, Sao Paolo, Not set
Real e Portuguesa de Beneficéncia - Hospital Beneficéncia Portuguesa (BP) - Unidade Paulista, São Paulo, Not set
Clinica de Pesquisas e Centro de Estudos em Oncolo, São Paulo, Not set
Fundação Pio XII - Hospital de Amor de Barretos, São Paulo, Not set
Nucleo de Pesquisa Clinica da Rede Sao Camilo, São Paulo, Not set
Cross Cancer Institute, Edmonton, Not set
QEII Health Sciences Centre, Halifax, Not set
Grand River Regional Cancer Centre at Grand River Hospital, Kitchener, Not set
London Health Sciences Centre, London, Not set
McGill University Health Centre, Montreal, Not set
Jewish General Hospital Department of Medical Oncology, Montréal, Not set
Ottawa Hospital - General Campus, Ottawa, Not set
CISSS du Bas-Saint-Laurent - Hôpital régional de Rimouski, Rimouski, Not set
Sunnybrook Research Institute, Toronto, Not set
Mount Sinai Hospital, Toronto, Not set
British Columbia Cancer - Vancouver, Vancouver, Not set
Oncovida - Santiago, Providencia, Not set
Clínica IRAM, Santiago DE CHILE, Not set
Centro de Oncología de Precisión, Santiago Region, Not set
Clínica Alemana, Santiago, Not set
James Lind Centro de Investigacion del Cancer, Temuco, Not set
Cancer Hospital Chinese Academy of Medical Sciences, Beijing, Not set
Peking University People's Hospital, Beijing, Not set
Beijing Cancer Hospital, Beijing, Not set
The First Medical Center of Chinese PLA General Hospital, Beijing, Not set
The Second Xiangya Hospital of Central South University, Changsha, Not set
Sichuan Cancer Hospital, Chengdu, Not set
West China Hospital, Sichuan University, Chengdu, Not set
The First Affiliated Hospital of Chongqing Medical University, Chongqing, Not set
Chongqing University Cancer Hospital, Chongqing, Not set
Deyang People's Hospital, Deyang, Not set
Sun Yat-Sen University Cancer Center, Guangzhou, Not set
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Not set
Harbin Medical University Cancer Hospital, Harbin, Not set
Anhui Provincial Cancer Hospital, Hefei, Not set
The Second Hospital of Anhui Medical University, Hefei, Not set
The Second Hospital of Jilin University, Jilin Sheng, Not set
The Second Hospital of Shandong University, Jinan, Not set
Shandong Cancer Hospital, Jinan, Not set
Nanchang People's hospital, Nanchang, Not set
The First Affiliated Hospital of Guangxi Medical University, Nanning, Not set
Tianjin Medical University Cancer Institute& Hospital, Tianjin, Not set
Weihai Municipal Hospital, Weihai, Not set
Hubei Cancer Hospital, Wuhan, Not set
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Not set
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Not set
The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Not set
The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang, Not set
The First Affiliated Hospital of Wenzhou Medical University, Zhejiang, Not set
Masarykuv onkologicky ustav, klinika komplexni onkologickie pece, Brno, Not set
Fakultní Thomayerova nemocnice, Hradec Kralove, Not set
Fakultni nemocnice Hradec Kravlove, Klinika onkologie a radioterapie, Hradec Králové, Not set
Fakultni nemocnice Olomouc, Onkologicka klinika, Olomouc, Not set
Vseobecna Fakultni Nemocnice v Praze, Prague, Not set
Fakultni nemocnice Karlovske Vinohrady, Radioterapeuticka a onkologicka klinika, Praha, Not set
Sainte Catherine Institut du Cancer Avignon Provence, Avignon, Not set
Centre Hospitalier Régional et Universitaire de Be, Besancon, Not set
Hôpital Morvan, Institut de cancérologie, Brest, Not set
Centre francois Baclesse, Caen, Not set
Centre Jean Perrin, Clermont Ferrand, Not set
Centre de Cancérologie du Grand Montpellier, Montpellier, Not set
Hôpital Privé du Confluent, Nantes, Not set
Hospices Civils de Lyon Hôpital Lyon Sud, Pierre-benite, Not set
Centre Armoricain de Radiothérapie, dImagerie Méd, Plerin, Not set
Centre Eugène Marquis, Rennes Cedex, Not set
Institut Claudius Regaud - IUCT-O, Toulouse, Not set
Institut Gustave Roussy, Villejuif, Not set
Helios Klinikum Berlin-Buch, Berlin, Not set
Gynakologisches Zentrum Bonn, Schwerpunkt Gyn. Onkologie,, Bonn, Not set
Universitätsklinikum Erlangen, Frauen klinik, Erlangen, Not set
Kliniken Essen-Mitte - Evangelische Huyssens-Stift Breast Unit, Essen, Not set
Praxis für interdisziplinäre Onkologie & Hämatolog, Freiburg, Not set
Universitatsklinikum Hamburg-Eppendorf, Hamburg, Not set
Facharztzentrum Eppendorf, Hamburg, Not set
Nationales Centrum für Tumorerkrankungen - Heidelb, Heidelberg, Not set
Klinik Frauenheilkunde, Uniklinik ClO, Studienzentrale, Köln, Not set
Universitätsklinikum Schleswig-Holstein Institut fur Klinische Chermie, Lübeck, Not set
Universitatsklinikum Mannheim GmBH, Frauenklinik, Mannheim, Not set
Universitätsklinikum Münster, Bereich Senologie an der klinik fur Frauenheilkunde und Gerburtschilfe, Munster, Not set
Evangelisches Krankenhaus Bethesda Mönchengladbach, Mönchengladbach, Not set
Rotkreuzklinikum Munchen, München, Not set
Klinik und Poliklinik für Frauenheilkunde, München, Not set
Universitätsklinikum Tübingen, Tübingen, Not set
St. Josefs-Hospital Wiesbaden GmbH , Gynäkologie und Geburtshilfe, Wiesbaden, Not set
Hong Kong Integrated Oncology Centre, Hong Kong, Not set
Queen Mary Hospital, Hong Kong, Not set
Tuen Mun Hospital, Hong Kong, Not set
Prince of Wales Hospital - Hong Kong, New Territories, Not set
Queen Mary Hospital, Pok Fu Lam, Not set
Uzsoki Utcai Kornaz, Onkoradiologiai Osztaly, Budapest, Not set
Debreceni Egyetem Klinikai Központ, Debrecen, Not set
Petz Aladar Egyetemi Oktaté Kérhaz - Osztaly, Gyor, Not set
Soroka Medical Center, Beer-Sheva, Not set
Rambam Health Care Campus, Haifa, Not set
Shaare Zedek Medical Center, Jerusalem, Not set
Hadassah - Hebrew University Medical Center, Jerusalem, Not set
Meir Medical Center, Kfar Saba, Not set
Rabin Medical Center, Petah Tikva, Not set
Kaplan Medical Center, Rehovot, Not set
Sheba Medical Center Hospital - Tel Hashomer, Tel Aviv, Not set
Tel Aviv Sourasky Medical Center, Tel Aviv, Not set
IRCCS Istituto Tumori "G.Paolo II", Bari, Not set
SSD Oncologia Medica Addarii-Zamagni, IRCSS Azienda Ospedaliero-Universitaria di Bologna - Policlinico di Sant'Orsola, Bologna, Not set
UO Oncologia, ASST degli Spedali Civili di Brescia, Brescia, Not set
IRCSS Ospedale Policlinico San Martino, Genova GE, Not set
S.C. Oncologia medica, ASST di Lecco, Lecco, Not set
Presidio Ospedaliero di Lucca, Lucca, Not set
Ospedale Generale Provinciale - Macerata, Macerata, Not set
Fondazione IRCCS - Istituto Nazionale dei Tumori, Milano, Not set
Istituto Europeo di Oncologia, Milan, Not set
Azienda Socio Sanitaria Territoriale, Monza, Not set
Oncologia Medica Senologica Sperimentale - Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Napoli, Not set
Azienda Ospedaliero-Universitaria Maggiore della C, Novara, Not set
Istituto Oncologico Veneto - IRCCS, Padova, Not set
S.O.C Patologia Clinica (Laboratorio Analisi), Nuovo Ospedale di Prato - Santo Stefano, Prato, Not set
AOU Policlinico Umberto I, Roma, Not set
Fondazione Policlinico Universitario Agostino Geme, Rome, Not set
Azienda Ospedaliera Universitaria Senese - Losped, Siena, Not set
Aichi Cancer Center Hospital, Aichi, Not set
Tohoku University Hospital, Aoba-ku, Not set
Juntendo University Hospital, Bunkyo-ku, Not set
Chiba Cancer Center, Chuo-ku, Not set
Osaka Prefectural Hospital Organization - Osaka In, Chuo-ku, Not set
Shikoku Cancer Center, Ehime, Not set
Fukushima Medical University Hospital, Fukushima, Not set
Saitama Cancer Center, Inamachi, Not set
Hakuaikai Sagara Hospital, Kagoshima-shi, Not set
Tokai University Hospital, Kanagawa, Not set
National Cancer Center Hospital East, Kashiwa, Not set
Cancer Institute Hospital of JFCR, Koto-ku, Not set
Kumamoto University Hospital, Kumamoto- shi, Not set
Kure Medical Center And Chugoku Cancer Center, Kure, Not set
Mie University Hospital, Mie, Not set
National Hospital Organization Kyushu Cancer Center, Minami-ku, Not set
Nagoya University Hospital, Nagoya, Not set
Nagoya City University Hospital, Nagoya, Not set
Hiroshima City Hiroshima Citizens Hospital, Naka-ku, Not set
Niigata Cancer Center Hospital, Niigata-shi, Not set
Okayama University Hospital, Okayama, Not set
Gunma Prefectural Cancer Center, Ota, Not set
Kyoto University Hospital, Sakyo-ku, Not set
Hokkaido Cancer Center, Sapporo, Not set
Shizuoka General Hospital, Shizuoka-city, Not set
Shizuoka Cancer Center, Shizuoka, Not set
Osaka University Hospital, Suita, Not set
Showa University Hospital, Tokyo, Not set
Kanagawa Cancer Center, Yokohama, Not set
National Cancer Center, Goyang-si Gyeonggi-do, Not set
Seoul National University Bundang Hospital, Seongnam-si, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Not set
Korea University Anam Hospital, Seoul, Not set
Seoul National University Hospital, Seoul, Not set
Hospital Pulau Pinang, Georgetown, Not set
Hospital Sultan Ismail, Johor Bahru, Not set
Hospital Kuala Lumpur, Kuala Lumpur, Not set
Pantai Hospital Kuala Lumpur, Kuala Lumpur, Not set
University Malaya Medical Centre (UMMC), Kuala Lumpur, Not set
Institut Kanser Negara, Putrajaya, Not set
Hospital Wanita dan Kanak-Kanak Sabah, Sabah, Not set
Sarawak General Hospital, Sarawak, Not set
Icaro Investigaciones en Medicina, Chihuahua, Not set
Cryptex Investigación Clínica, Ciudad de Mexico, Not set
Sinacor - Centro para el Desarrollo de la Medicina, Culiacan, Not set
Panamerican Clinical Research Mexico - Guadalajara, Guadalajara, Not set
Medical Care and Research S.A. de C.V., Merida, Not set
Avix Investigacion Clinica S.C., Monterrey, Not set
Fucam A.C., México, Not set
Oncológico Potosino, San Luis Potosi, Not set
FAICIC Clínical Research, Veracruz, Not set
iBiomed - Investigacion Biomedica para el Desarrol, Zapopan, Not set
Amphia Ziekenhuis - Breda Langendijk, Breda, Not set
Universitair Medisch Centrum Groningen, Groningen, Not set
Medisch Centrum Leeuwarden, Leeuwarden, Not set
Maastricht Universitair Medisch Centrum, Maastricht, Not set
Erasmus Medisch Centrum, Rotterdam, Not set
Uniwersyteckie Centrum Kliniczne, Klinika Onkologii i Radioterapii, Gdansk, Not set
Narodowy Instytut Onkologii im. Marii Sklodowskiej, Gliwice, Not set
SP ZOZ Opolskie Centrum Onkologii im. prof. Tadeusza Koszarowskiego, Opole, Not set
Wielkopolskie Centrum Onkologii im. Marii Sklodowskiej-Curie, Poznan, Not set
Mazowiecki Szpital Wojewódzki im. w. Jana Pawa II, Siedlce, Not set
Wojskowy Instytut Medyczny, Warsaw, Not set
Narodowy Instytut Onkologii im.Marii Marii Sklodowskiej, Warszawa, Not set
Ponce Medical School Foundation Inc., Ponce, Not set
Clinical Research Puerto Rico, San Juan, Not set
Spitalul Clinic Filantropia, Bucharest, Not set
SC Medisprof SRL, Cluj-Napoca, Not set
Institutal Oncologic, Prof. Dr Ion Chiricuta, Cluj-Napoca, Not set
Centrul De Oncologie Sf Nectarie, Craiova, Not set
S.C. Oncomed S.R.L, Timisoara, Not set
National University Hospital, Singapore, Not set
Raffles Hospital, Singapore, Not set
Curie Oncology, Singapore, Not set
Onkologicky Ustav Sv. Alzbety, Bratislava, Not set
Národný onkologický ústav, Bratislava, Not set
Vychodoslovensky onkologicky ustav, a.s., Oddelenie klinickej onkologie, Košice, Not set
Nemocnica Partizánske, Partizánske, Not set
Hopelands Cancer Centre, Hilton, Not set
Wits Clinical Research, Johannesburg, Not set
The Medical Oncology Centre of Rosebank, Johannesburg, Not set
University of Pretoria, Pretoria, Not set
Hospital Teresa Herrera - Materno Infantil, A Coruña, Not set
Hospital Universitari Dexeus, Barcelona, Not set
CEIm Hospital General Universitario Gregorio Maranon, Barcelona, Not set
Hospital Clinic Barcelona, Barcelona, Not set
Hospital Universitari Vall d'Hebrón, Barcelona, Not set
Hospital de la Santa Creu i Sant Pau, Barcelona, Not set
Hospital Universitario de Basurto, Bilbo, Not set
Hospital Universitari Arnau de Vilanova, Lleida, Not set
Hospital General Universitario Gregorio Maranon, Madrid, Not set
MD Anderson Cancer Center Madrid, Madrid, Not set
Hospital Universitario Fundación Jiménez Díaz, Madrid, Not set
Hospital Universitario Virgen de la Victoria, Malaga, Not set
Hospital General Universitario Morales Meseguer, Murcia, Not set
Hospital Unviersitario Virgen del Rocio, Sevilla, Not set
Hospital Universitario Virgen Macarena, Sevilla, Not set
Hospital Universitario de Canarias, Tenerife, Not set
Hospital Clínico Universitario de Valencia, Valencia, Not set
Kantonsspital Baden, Baden, Not set
Kantonsspital Baselland - Standort Liestal, Liestal, Not set
Kantonsspital St.Gallen, St. Gallen, Not set
Kantonsspital Winterthur, Winterthur, Not set
Brust-Zentrum AG, Zürich, Not set
Changhua Christian Hospital, Changhua, Not set
Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien City, Not set
E-DA Cancer Hospital, Kaohsiung City, Not set
Kaohsiung, Kaohsiung City, Not set
Taipei Medical University - Shuang Ho Hospital, Ministry of Health and Welfare, New Taipei City, Not set
Taichung, Taichung, Not set
Taichung Veterans General Hospital, Taichung, Not set
National Cheng Kung University Hospital, Tainan City, Not set
Chi Mei Hospital, Lioying, Tainan City, Not set
National Taiwan University Hospital, Taipei, Not set
MacKay Medical Foundation The Presbyterian Church in Taiwan MacKay Memorial Hospital, Taipei, Not set
Tri-Service General Hospital, Taipei, Not set
Chang Gung Memorial Hospital, Linkou, Taoyuan City, Not set
Baskent Uni. Dr Turgut Noyan Uyg. ve Aras. Merkezi, Adana, Not set
Memorial Ankara Hastanesi, Ankara, Not set
Ankara Il Saglik Mudurlugu SBU Gulhane Egitim Ve A, Ankara, Not set
Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi, Ankara, Not set
Hacettepe Üniversitesi Hastanesi, Ankara, Not set
Trakya Universitesi Tip Fakultesi Hastanesi, Edirne, Not set
Istanbul Il Saglik Mudurlugu Goztepe Prof. Dr. Sul, Istanbul, Not set
Medipol Mega Universite Hastanesi, Istanbul, Not set
Ege Universitesi Hastanesi, Izmir, Not set
Medicana International Izmir Hastanesi, İzmir, Not set
Acibadem Maslak Hastanesi, Sariyer, Not set
VKV Amerikan Hastanesi, Sisli, Not set
Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, Not set
Cancer Research UK Beatson Institute, Glasgow, Not set
Leeds Teaching Hospitals NHS Trust, Leeds, Not set
Barts Health NHS Trust, London, Not set
Royal Free London NHS Foundation Trust, London, Not set
Guy's and Saint Thomas' NHS Foundation Trust, London, Not set
University College London Hospitals NHS Foundation, London, Not set
Conditions: Triple Negative Breast Cancer, PD-L1 Negative
Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma.
Recruiting
Master protocol: The main goal of this master clinical study is to evaluate the efficacy and safety of multiple novel combination therapies in participants with head and neck squamous cell carcinoma (HNSCC) in various substudies.
Master protocol: The main goal of this master clinical study is to evaluate the efficacy and safety of multiple novel combination therapies in participants with head and neck squamous cell carcinoma (HNSCC) in various substudies. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/09/2025
Locations: Siteman Cancer Center, Saint Louis, Missouri +24 locations
Siteman Cancer Center, Saint Louis, Missouri
Tennessee Oncology, PLLC - Greco-Hainsworth Centers for Research, Nashville, Tennessee
The University of Texas, MD Anderson Cancer Center, Houston, Texas
Monash Health, Clayton, Victoria
Alfred Health, Melbourne, Victoria
ICON Cancer Center, Kurralta Park, Not set
Westmead Hospital, Sydney, Not set
Sichuan Cancer Hospital, Chengdu, Not set
Zhejiang Cancer Hospital, Hangzhou, Not set
Guangxi Medical University Cancer Hospital, Nanning, Not set
Shanghai East Hospital, Shanghai, Not set
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Not set
CHU de Bordeaux, Pessac, Not set
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Not set
Istituto Nazionale Tumori Fondazione G. Pascale, Napoli, Not set
Sarawak General Hospital, Sarawak, Not set
Hospital Universitario Virgen del Rocio, Sevilla, Not set
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City, Not set
Chang Gung Medical Foundation Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Not set
China Medical University Hospital, Taichung, Not set
National Taiwan University Hospital, Taipei City, Not set
Taipei Veterans General Hospital, Taipei City, Not set
Chang Gung Memorial Hospital, Linkou, Taoyuan, Not set
Barts Health NHS Foundation Trust, London, Not set
The Royal Marsden NHS Foundation Trust, London, Not set
Conditions: Head and Neck Squamous Cell Carcinoma
Study of Efficacy and Safety of NIS793 (With and Without Spartalizumab) in Combination With SOC Chemotherapy in First-line Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC)
Terminated
The purpose of this Phase II study is to assess the efficacy and safety of NIS793 with and without spartalizumab in combination with gemcitabine/nab-paclitaxel versus gemcitabine/nab-paclitaxel in previously untreated mPDAC.
The purpose of this Phase II study is to assess the efficacy and safety of NIS793 with and without spartalizumab in combination with gemcitabine/nab-paclitaxel versus gemcitabine/nab-paclitaxel in previously untreated mPDAC. Read Less
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
05/08/2025
Locations: Winship Cancer Institute, Atlanta, Georgia +30 locations
Winship Cancer Institute, Atlanta, Georgia
Sidney Kimmel CCC At JH, Baltimore, Maryland
Massachusetts General Hospital, Boston, Massachusetts
Beth Israel Deaconess Medical Cente, Boston, Massachusetts
Univ of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania
Novartis Investigative Site, Westmead, New South Wales
Novartis Investigative Site, Melbourne, Victoria
Novartis Investigative Site, Salzburg, Not set
Novartis Investigative Site, Wien, Not set
Novartis Investigative Site, Liege, Not set
Novartis Investigative Site, Brno, Czech Republic
Novartis Investigative Site, Helsinki, Not set
Novartis Investigative Site, Paris 10, Not set
Novartis Investigative Site, Toulouse 4, Not set
Novartis Investigative Site, Essen, Not set
Novartis Investigative Site, Heidelberg, Not set
Novartis Investigative Site, Ulm, Not set
Novartis Investigative Site, Milano, MI
Novartis Investigative Site, Milano, MI
Novartis Investigative Site, Rozzano, MI
Novartis Investigative Site, Verona, VR
Novartis Investigative Site, Singapore, Not set
Novartis Investigative Site, Singapore, Not set
Novartis Investigative Site, Barcelona, Catalunya
Novartis Investigative Site, Barcelona, Catalunya
Novartis Investigative Site, Madrid, Not set
Novartis Investigative Site, St Gallen, Not set
Novartis Investigative Site, Zuerich, Not set
Novartis Investigative Site, Taichung, Not set
Novartis Investigative Site, Taipei, Not set
Novartis Investigative Site, Oxford, Not set
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Atezolizumab Trial in Endometrial Cancer - AtTEnd
Completed
Atezolizumab is an engineered humanised monoclonal immunoglobulin G1 antibody that binds selectively to PD-L1 and prevents its interaction with PD-1 and B7-1.
In May 2016 atezolizumab was approved by the FDA for patients with locally advanced or metastatic urothelial carcinoma who have disease progression during or following any platinum-containing chemotherapy, or within 12 months of receiving chemotherapy before surgery (neoadjuvant) or after surgery (adjuvant); in October 2016 it was approve... Read More
Atezolizumab is an engineered humanised monoclonal immunoglobulin G1 antibody that binds selectively to PD-L1 and prevents its interaction with PD-1 and B7-1.
In May 2016 atezolizumab was approved by the FDA for patients with locally advanced or metastatic urothelial carcinoma who have disease progression during or following any platinum-containing chemotherapy, or within 12 months of receiving chemotherapy before surgery (neoadjuvant) or after surgery (adjuvant); in October 2016 it was approved by the FDA for patients with metastatic non-small cell lung cancer (NSCLC) who have disease progression during or following platinum-containing chemotherapy, and have progressed on an appropriate FDA-approved targeted therapy if their tumor has EGFR or ALK gene abnormalities. Finally, in April 2017 atezolizumab was granted accelerated approval by FDA for the first-line treatment of patients with locally advanced or metastatic urothelial carcinoma who are not eligible for cisplatin chemotherapy. Combinations of atezolizumab with chemotherapeutic agents and/or targeted therapies were studied in different solid tumors such as melanoma, NSCLC, renal cell carcinoma and colorectal carcinoma. From these studies the AE profile of atezolizumab combinations were consistent with that of the individual agents.
Finally, preliminary results of a Phase Ia study of Atezolizumab (NCT01375842) monotherapy in relapsed endometrial cancer were reported as abstract at ASCO 2017. Fifteen patients were evaluated for safety and efficacy with a minimum follow-up of 11.2 months. No G4-5 related AEs occurred. Regarding efficacy ORR was 13% \[2/15\] by RECIST. Atezolizumab seemed to have a favorable safety profile, with durable clinical benefit in some patients. Further studies with atezolizumab are warranted given its promising results in advanced endometrial cancer and the limited efficacy of current treatment options. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/06/2025
Locations: Royal Adelaide hospital, Adelaide, Not set +92 locations
Royal Adelaide hospital, Adelaide, Not set
Border Medical Oncology Research Unit, Albury, Not set
Icon Cancer Centre, Auchenflower, Not set
Pindara Private Hospital, Benowa, Not set
Box Hill Hospital, Box Hill, Not set
Frankston Hospital, Frankston, Not set
Gosford Hospital, Gosford, Not set
Royal Brisbane and Women's Hospital, Herston, Not set
Royal Hobart Hospital, Hobart, Not set
Liverpool Hospital, Liverpool, Not set
Northern Cancer Institute, Saint Leonards, Not set
Darling Downs Hospital and Health Service - Toowoomba Hospital, Toowoomba, Not set
Calvary Mater Newcastle, Waratah, Not set
Wollongong Hospital, Wollongong, Not set
Medizinische Universitaet Graz - Universitätsklinik für Frauenheilkunde und Geburtshilfe, Graz, Not set
Medical University of Innsbruck, Innsbruck, Not set
Charité Universitätsmedizin Berlin, Berlin, Not set
Kliniken Essen Mitte, Essen, Not set
UniversitätsKlinikum Heidelberg, Mannheim, Not set
Klinikum der Ludwig-Maximilians-Universität München (LMU), Muenchen, Not set
AO SS Antonio e Biagio e Cesare Arrigo, Alessandria, Not set
Policlinico S. Orsola Malpighi, Bologna, Not set
Azienda Sanitaria dell'Alto Adige, Bolzano, Not set
ASST degli Spedali Civili di Brescia, Brescia, Not set
Fondazione Poliambulanza, Brescia, Not set
AOU Cagliari, Policlinico Universitario, Cagliari, Not set
AOU Careggi, Firenze, Not set
ASST di Lecco, Lecco, Not set
Ospedale San Luca, Lucca, Not set
Istituto Europeo di Oncologia, Milan, Not set
Ospedale San Gerardo, Monza, Not set
Istituto Oncologico Veneto (IOV), Padova, Not set
AOU di Parma, Parma, Not set
AOU Pisana, Pisa, Not set
AO Arcispedale Santa Maria Nuova, Reggio Emilia, Not set
Ausl Romagna, Rimini, Not set
Policlinico Umberto I, Università di Roma "La Sapienza", Roma, Not set
Ospedale di Sondrio ASST Valtellina e Alto Lario, Sondrio, Not set
Ospedale SS Trinità, Sora, Not set
AO Ordine Mauriziano, Torino, Not set
AOU Città della Salute e della Scienza di Torino - Ospedale Sant'Anna, Torino, Not set
P.O Sant'Andrea Vercelli, Vercelli, Not set
Hirosaki University Hospital, Aomori, Not set
National Cancer Center Hospital East, Chiba, Not set
Shikoku Cancer Center, Ehime, Not set
Kurume University Hospital, Fukuoka, Not set
Hokkaido University Hospital, Hokkaido, Not set
Tohoku University Hospital, Miyagi, Not set
Niigata University Medical＆Dental Hospital, Niigata, Not set
Osaka University Hospital, Osaka, Not set
Shizuoka Cancer Center, Shizuoka, Not set
Keio University Hospital, Tokyo, Not set
Keimyung University Dongsan Medical Center, Daegu, Not set
Ilsan Cha Medical Center, Gyeonggi-do, Not set
Seoul National University Bundang Hospital, Gyeonggi-do, Not set
Gachon University Gil Medical Center, Incheon, Not set
Asan Medical Center, Seoul, Not set
Gangnam Severance Hospital, Seoul, Not set
Konkuk University Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Seoul St. Mary's Hospital, Seoul, Not set
Severance Hospital, Seoul, Not set
Auckland city Hospital, Auckland, Not set
Hospital De Sant Pau I La Santa Creu, Barcelona, Not set
Hospital Universitario Vall d´Hebron Institute of Oncology (VHIO), Barcelona, Not set
Institut Català d'Oncologia (ICO) Girona, Girona, Not set
Institut Català d'Oncologia (ICO), L'Hospitalet- Hospital Duran I Reynals, Hospitalet de Llobregat, Not set
Hospital 12 de Octubre, Madrid, Not set
Hospital Universitario La Paz, Madrid, Not set
MD Anderson Cancer Center, Madrid, Not set
Hospital Universitario Central de Asturias, Oviedo, Not set
Hospital Clínico Universitario Santiago de Compostela, Santiago De Compostela, Not set
Hospital Universitario Miguel Servet Zaragoza, Zaragoza, Not set
Kantonsspital, Baden, Not set
Universitätsspital, Basel, Not set
IOSI, Bellinzona, Not set
Inselspital, Bern, Not set
Kantonsspital, Luzern, Not set
Frauenfeld, Münsterlingen, Not set
Kantonsspital, Winterthur, Not set
Universitätsspital, Zürich, Not set
Chang Gung Memorial Hospital-Kaohsiung, Kaohsiung City, Not set
Chang Gung Memorial Hospital-Linkou, Taoyuan City, Not set
Royal Derby Hospital, Derby, Not set
Royal Devon & Exeter Hospital, Exeter, Not set
Beatson West of Scotland Cancer Centre, Gartnavel General Hospital, Glasgow, Not set
Velindre Cancer Centre, Glasgow, Not set
Imperial College Healthcare NHS Trust, London, Not set
Royal Marsden Hospital, London, Not set
St Bartholomew's Hospital, London, Not set
The Christie NHS Foundation Trust, Manchester, Not set
NUHT - Nottingham University Hospital NHS Trust, Nottingham, Not set
Derriford Hospital, Plymouth, Not set
Conditions: Endometrial Cancer
Relacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer
Active Not Recruiting
The primary objectives of this study are to evaluate progression-free survival (PFS) by blinded independent central review (BICR) and overall survival (OS) (evaluated independently, as dual primary endpoints) in patients treated with intermittent regimen of Relacorilant in combination with nab-paclitaxel compared with patients treated with nab-paclitaxel monotherapy.
The primary objectives of this study are to evaluate progression-free survival (PFS) by blinded independent central review (BICR) and overall survival (OS) (evaluated independently, as dual primary endpoints) in patients treated with intermittent regimen of Relacorilant in combination with nab-paclitaxel compared with patients treated with nab-paclitaxel monotherapy. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/14/2025
Locations: Site 318, Phoenix, Arizona +116 locations
Site 318, Phoenix, Arizona
Site 277, Tucson, Arizona
Site 350, Irvine, California
Site 364, La Jolla, California
Site 150, Palo Alto, California
Site 278, San Francisco, California
Site 014, San Francisco, California
Site 316, Solvang, California
Site 032, Aurora, Colorado
Site 335, Miami Beach, Florida
Site 042, Weston, Florida
Site 009, Atlanta, Georgia
Site 272, Atlanta, Georgia
Site 372, Gainesville, Georgia
Site 291, Savannah, Georgia
Site 315, Evanston, Illinois
Site 314, Hinsdale, Illinois
Site 346, Urbana, Illinois
Site 339, Indianapolis, Indiana
Site 200, Overland Park, Kansas
Site 334, Overland Park, Kansas
Site 279, Louisville, Kentucky
Site 128, Boston, Massachusetts
Site 288, New Brunswick, New Jersey
Site 292, Albuquerque, New Mexico
Site 275, Flushing, New York
Site 298, Cincinnati, Ohio
Site 304, Cincinnati, Ohio
Site 280, Portland, Oregon
Site 317, Portland, Oregon
Site 049, Portland, Oregon
Site 337, Bethlehem, Pennsylvania
Site 127, Pittsburgh, Pennsylvania
Site 276, Rapid City, South Dakota
Site 368, Germantown, Tennessee
Site 281, Nashville, Tennessee
Site 229, Austin, Texas
Site 312, Bedford, Texas
Site 297, Fort Worth, Texas
Site 392, San Antonio, Texas
Site 301, The Woodlands, Texas
Site 300, Norfolk, Virginia
Site 365, Richmond, Virginia
Site 121, Milwaukee, Wisconsin
Site 393, Caba, Buenos Aires
Site 381, Ciudad Autonoma de Buenos Aire, Buenos Aires
Site 415, Ciudad de Cordoba, Cordoba
Site 401, Ciudad de Cordoba, Cordoba
Site 395, Ciudad de Cordoba, Cordoba
Site 404, Ciudad de Mendoza, Mendoza
Site 391, Rosario, Santa Fe
Site 412, Rosario, Santa Fe
Site 426, St. Leonards, New South Wales
Site 417, Benowa, Queensland
Site 414, Melbourne, Victoria
Site 419, Melbourne, Victoria
Site 328, Aalst, Not set
Site 109, Brussels, Not set
Site 326, Charleroi, Not set
Site 325, Hasselt, Not set
Site 108, Leuven, Not set
Site 327, Liège, Not set
Site 384, Salvador, Bahia
Site 424, Brasília, Brasília - DF
Site 382, Fortaleza, Ceara
Site 383, Belo Horizonte, Minas Gerais
Site 390, Natal, Rio Grande Do Norte
Site 413, São Paulo, SP
Site 421, Porto Alegre, Not set
Site 380, Rio De Janeiro, Not set
Site 376, São Paulo, Not set
Site 389, São Paulo, Not set
Site 413, São Paulo, Not set
Site 374, São Paulo, Not set
Site 001, São Paulo, Not set
Site 117, Toronto, Ontario
Site 273, Montréal, Quebec
Site 306, Lille, Not set
Site 347, Montpellier, Not set
Site 307, Nancy, Not set
Site 310, Nice, Not set
Site 289, Paris, Not set
Site 323, Plérin, Not set
Site 322, Budapest, Not set
Site 290, Debrecen, Not set
Site 348, Győr, Not set
Site 309, Haifa, Not set
Site 080, Jerusalem, Not set
Site 203, Tel Aviv, Not set
Site 321, Catania, Not set
Site 320, Legnago, Not set
Site 122, Milano, Not set
Site 295, Pavia, Not set
Site 161, Roma, Not set
Site 124, Rome, Not set
Site 293, Torino, Not set
Site 319, Treviso, Not set
Site 397, Gyeonggi-do, Not set
Site 399, Seoul, Not set
Site 398, Seoul, Not set
Site 403, Seoul, Not set
Site 400, Seoul, Not set
Site 396, Seoul, Not set
Site 402, Seoul, Not set
Site 409, Seoul, Not set
Site 341, Gdynia, Not set
Site 331, Poznań, Not set
Site 329, Siedlce, Not set
Site 349, Badalona, Not set
Site 311, San Sebastián, Not set
Site 330, Valencia, Not set
Site 367, Brighton, East Sussex
Site 351, Taunton, Somerset
Site 366, Cheltenham, Not set
Site 055, London, Not set
Site 344, Manchester, Not set
Site 345, Northwood, Not set
Conditions: Ovarian Neoplasm, Fallopian Tube Neoplasms, Peritoneal Neoplasms
Study to Assess the Safety and Tolerability of a PARP Inhibitor in Combination With Carboplatin and/or Paclitaxel
Completed
The purpose of this study is to identify a safe and tolerable dose of the drug KU-0059436 that can be given in combination with carboplatin and/or Paclitaxel chemotherapy.
The purpose of this study is to identify a safe and tolerable dose of the drug KU-0059436 that can be given in combination with carboplatin and/or Paclitaxel chemotherapy. Read Less
Gender:
ALL
Ages:
Between 18 years and 130 years
Trial Updated:
04/10/2025
Locations: Research Site, Brussels, Not set +3 locations
Research Site, Brussels, Not set
Research Site, Amsterdam, Not set
Research Site, Rotterdam, Not set
Research Site, London, Not set
Conditions: Triple Negative Metastatic Breast Cancer, Advanced Ovarian Cancer, Carboplatin, Paclitaxel
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