All Clinical Trials in United Kingdom

A listing of 3097 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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RCT of Implantable Defibrillators in Patients with Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure

NCT05568069

Recruiting

BRITISH is a UK multicentre trial of patients who have been diagnosed with heart failure due to Non-Ischemic Cardiomyopathy (NICM, or heart failure that is not caused by blocked heart arteries. Participants will be randomised into two groups. Half the participants will receive an Implantable Cardioverter-Defibrillator (ICD) and the other half will not. The aim of the study will be to compare all-cause mortality (death from any cause) between these two groups at 36 months, and longer-term to 10 y... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

01/23/2025

Locations: Wycombe Hospital, High Wycombe, Buckinghamshire +46 locations

Wycombe Hospital, High Wycombe, Buckinghamshire

Derriford Hospital, Plymouth, Devon

Royal Bournemouth Hospital, Bournemouth, Dorset

Durham & Darlington NHS Foundation Trust, Darlington, Durham

Royal Sussex County Hospital, Brighton, East Sussex

Essex Cardiothoracic Centre, Basildon, Essex

James Paget University Hospitals NHS FT, Gorleston-on-Sea, Great Yarmouth

Portsmouth Hospitals University NHS Trust, Portsmouth, Hampshire

Southampton Clinical Trials Unit, Southampton, Hampshire

University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire

Kent & Canterbury Hospital, Canterbury, Kent

Maidstone Hospital, Maidstone & Tunbridge Wells NHS Trust, Maidstone, Kent

Blackpool Victoria Hospiatal, Blackpool, Lancashire

Liverpool Heart & Chest, Liverpool, Lancashire

Glenfield Hospital, Leicester, Leicestershire

St George's Hospital, Tooting, London

Newcastle Freeman Hospital, Newcastle, Newcastle upon Tyne

The James Cook University Hospital, Middlesbrough, North Yorkshire

Wansbeck General Hospital, Ashington, Northumbria

Scarborough Hospital, Scarborough, Nortrh Yorkshire

Nottingham City Hospital, Nottingham, Nottinghamshire

The John Radcliffe Hospital, Oxford, Oxfordshire

Aberdeen Royal Infirmary, Aberdeen, Scotland

Royal Infirmary of Edinburgh, Edinburgh, Scotland

Musgrove Park Hospital, Taunton, Somerset

Northern General Hospital, Sheffield, South Yorkshire

University Hospital of North Tees, Hardwick, Stockton-on-Tees

Frimley Park Hospital, Camberley, Surrey

Surrey & Sussex Healthcare NHS Trust, Redhill, Surrey

University Hospital of Wales, Cardiff, Wales

University Hospital Coventry, Coventry, Warwickshire

New Cross Hospital, Wolverhampton, West Midlands

St Richards Hospital, Chichester, West Sussex

Leeds General Infirmary, Leeds, West Yorkshire

Pinderfields Hospital, Wakefield, West Yorkshire

Worcestershire Royal Hospital, Worcester, Worcestershire

Wythenshaw Hospital, Manchester, Wythenshaw

Castle Hill Hospital, Hull, Yorkshire

Royal Devon & Exeter Hospital, Exeter, Not set

St Bartholomew's Hospital, London, Not set

Royal Free Hospital, London, Not set

Guy's Hospital, London, Not set

King's College Hospital, London, Not set

Royal Brompton Hospital, London, Not set

Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, Not set

Fairfield General Hospital, Northern Care Alliance NHS FT, Manchester, Not set

Morriston Hospital, Swansea, Not set

Conditions: Heart Failure

Learn More ›

A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

NCT04961567

Recruiting

In this study, researchers will learn more about a study drug called litifilimab (BIIB059) in participants with systemic lupus erythematosus (SLE). The study will focus on participants who have active disease and are already taking standard of care medications. These may include antimalarials, steroids, and immunosuppressants. The main objective of the study is to learn about the effect litifilimab has on lowering the activity of the disease. The main question researchers want to answer is: -... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

01/23/2025

Locations: University of Alabama at Birmingham, Birmingham, Alabama +178 locations

University of Alabama at Birmingham, Birmingham, Alabama

Arizona Arthritis & Rheumatology Associates, P.C., Glendale, Arizona

Care Access Research - Huntington BeachCare Access Research - Huntington Beach, Huntington Beach, California

Valerius Medical Group, Los Alamitos, California

The Practice of Medicine, Los Angeles, California

R. Srinivasan, M.D., Inc. dba Monterey Park Medical Center, Monterey Park, California

Neurovations, Napa, California

Joo-Hyung Lee MD, Orange, California

Medvin Clinical Research, Whittier, California

RASF - Clinical Research Center, Boca Raton, Florida

University of Florida, Gainesville, Florida

Vida Clinical Research, Kissimmee, Florida

University of Miami Miller School of Medicine, Miami, Florida

HMD Research, LLC, Orlando, Florida

Clinical Research of West Florida, Inc., Tampa, Florida

The Emory Clinic Emory University, Atlanta, Georgia

Jefrey Lieberman, M.D., P.C., Decatur, Georgia

Southeastern Rheumatology Alliance dba Arthritis Center of North Georgia, Gainesville, Georgia

RNA America Health Sciences, Gainesville, Georgia

EBGS Clinical Trials, Snellville, Georgia

Rush University Medical Center, Chicago, Illinois

Boston University School of Medicine, Boston, Massachusetts

DM Clinical Research - Boston, Brookline, Massachusetts

University of Massachusetts, Worcester, Massachusetts

Saint Louis Rheumatology, Saint Louis, Missouri

Arthritis & Osteoporosis Associates, PA, Freehold, New Jersey

Arthritis and Osteoporosis Associates of New Mexico, Las Cruces, New Mexico

DJL Clinical Research, PLLC, Charlotte, North Carolina

Carolina Arthritis Associates, Wilmington, North Carolina

University of Cincinnati, Cincinnati, Ohio

STAT Research, Dayton, Ohio

Piedmont Arthritis Clinic, P.A., Greenville, South Carolina

Low Country Rheumatology, PA, Summerville, South Carolina

West Tennessee Research Institute, Jackson, Tennessee

Arthritis & Rheumatology Institute, Allen, Texas

Office of John P. Lavery M.D., PA, Allen, Texas

Tekton Research, Austin, Texas

Precision Comprehensive Clinical Research Solutions, Colleyville, Texas

R and H Clinical Research, Katy, Texas

Prime Clinical Research, Mansfield, Texas

SouthWest Rheumatology Research, LLC, Mesquite, Texas

Sun Research Institute, LLC, San Antonio, Texas

The University of Texas Health Science Center at San Antonio, San Antonio, Texas

Swedish Medical Center, Seattle, Washington

Hospital General de Agudos Dr. J. M. Ramos Mejia, Ciudad Autonoma Buenos Aires, Buenos Aires

Centro de Investigaciones Medicas Mar del Plata, Mar del Plata, Buenos Aires

Policlìnica Red Omip S.A - Ensayos Clinicos GC, Mar del Plata, Buenos Aires

Centro Dermatologico Schejtman, San Miguel, Buenos Aires

APRILLUS Asistencia e Investigacion, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma Buenos Aires

Instituto de Investigaciones Clinicas Quilmes, Buenos Aires, Provincia De Buenos Aires

Hospital Italiano de La Plata, Buenos Aires, Provincia De Buenos Aires

Instituto CAICI, Rosario, Santa Fe

Clinica Mayo de Urgencias Medicas Cruz Blanca SRL, San Miguel de Tucuman, Tucuman

Centro de Investigaciones Medicas Tucuman, San Miguel de Tucuman, Tucuman

Investigaciones Clinicas Tucuman, San Miguel de Tucumán, Tucuman

Centro Medico Dra Laura Maffei Investigacion Clinica Aplicada, Ciudad Autonoma Buenos Aires, Not set

STAT Research S.A., Ciudad Autonoma Buenos Aires, Not set

Organizacion Medica de Investigacion (OMI), Ciudad Autonoma Buenos Aires, Not set

Hospital Britanico de Buenos Aires, Ciudad Autonoma Buenos Aires, Not set

Centro Privado de Medicina Familiar - Mind Out Research, Ciudad Autonoma Buenos Aires, Not set

Centro Medico Barrio Parque, Ciudad Autonoma de Buenos Aires, Not set

Sanatorio Allende, Cordoba, Not set

Instituto de Reumatologia, Mendoza, Not set

CER San Juan Centro Polivalente de Asistencia e Inv. Clinica, San Juan, Not set

UZ Leuven, Leuven, Not set

Centre Hospitalier Universitaire de Liege, Liege, Not set

The Waterside Clinic, Barrie, Ontario

Hamilton Health Sciences Corporation, Hamilton, Ontario

The Ottawa Hospital - General Campus, Ottawa, Ontario

Peking Union Medical College Hospital, Beijing, Beijing

Dongguan People's Hospital, Dongguan, Guangdong

Guangdong Second Provincial General Hospital, Guangzhou, Guangdong

Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong

Shenzhen People's Hospital, Shenzhen, Guangdong

Hainan General Hospital, Haikou, Hainan

EC of Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei

The second Xiangya Hospital of Central South University, Changsha, Hunan

ZhuZhou Central Hospital, ZhuZhou, Hunan

The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi

Jiangxi Pingxiang People's Hospital, Pingxiang, Jiangxi

Jilin Province People's Hospital, Changchun, Jilin

Yanbian University Hospital (Yanbian Hospital), Yanji, Jilin

Jiujiang No.1 People's Hospital, Jiujiang, Jiujiang

Binzhou Medical University Hospital, Binzhou, Shandong

Renji Hospital Shanghai Jiaotong University School of Medicine - West Branch, Shanghai, Shanghai

Ruijin Hospital of Shanghai Jiaotong University School of Medicine, Shanghai, Shanghai

The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan

Tianjin Medical University General Hospital, Tianjin, Tianjin

The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang

Wenzhou People's Hospital, Wenzhou, Zhejiang

Beijing Chaoyang Hospital, Capital Medical University, Beijing, Not set

Xuanwu Hospital Capital Medical University, Beijing, Not set

The First Hospital of Jilin University, Changchun City, Not set

Xiangya Hospital, Central South University, Changsha, Not set

Centro de Investigacion Medico Asistencial S.A.S, Barranquilla, Not set

Clínica de la Costa Ltda., Barranquilla, Not set

Centro de Investigacion en Reumatologia y Especialidades Medicas CIREEM S.A.S., Bogotá, Not set

Servimed S.A.S., Bucaramanga, Not set

IPS Centro Medico Julián Coronel S.A., Cali, Not set

Preventive Care Ltda, Chia, Not set

Healthy Medical Center, Zipaquirá, Not set

Revmatologie s.r.o., Brno, Not set

Fakultni nemocnice Olomouc, Olomouc, Not set

Universitaetsmedizin Goettingen, Gottingen, Niedersachsen

Medizinische Hochschule Hannover, Hannover, Niedersachsen

Universitaetsklinikum Koeln, Koeln, Nordrhein Westfalen

Universitaetsklinikum Muenster, Muenster, Nordrhein Westfalen

Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz, Mainz, Rheinland Pfalz

Obudai Egeszsegugyi Centrum Kft., Budapest, Not set

Del-pesti Centrumkorhaz - Orszagos Hematologiai es Infektologiai Intezet, Budapest, Not set

Bekes Varmegyei Kozponti Korhaz, Gyula, Not set

Vita Verum Medical Egeszsegugyi Szolgaltato Bt., Szekesfehervar, Not set

Vital Medical Center, Veszprem, Not set

Rambam Health Care Center, Haifa, Not set

Meir Medical Center, Kfar- Sava, Not set

Rabin Medical Center-Beilinson Campus, Petach-Tikva, Not set

Chaim Sheba Medical Center, Ramat Gan, Not set

Tel Aviv Sourasky Medical Center, Tel Aviv, Not set

Istituto Clinico Humanitas, Rozzano, Milano

Ospedale M. Scarlato, Scafati, Salerno

Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (Presidio Spedali Civili), Brescia, Not set

Azienda Ospedale-Università di Padova, Padova, Not set

Azienda Ospedaliero Universitaria Pisana, Pisa, Not set

Azienda Ospedaliera San Camillo Forlanini, Roma, Not set

Università Campus Bio-Medico di Roma, Roma, Not set

Azienda Ospedaliera Universitaria Policlinico Umberto I - Università di Roma La Sapienza, Roma, Not set

JCHO Chukyo Hospital, Nagoya-shi, Aichi-Ken

Fujita Health University Hospital, Toyoake-shi, Aichi-Ken

Chiba University Hospital, Chiba-shi, Chiba-Ken

NHO Chibahigashi National Hospital, Chiba-shi, Chiba-Ken

Chibaken Saiseikai Narashino Hospital, Narashino-shi, Chiba-Ken

KKR Hamanomachi Hospital, Fukuoka-shi, Fukuoka-Ken

NHO Kyushu Medical Center, Fukuoka-shi, Fukuoka-Ken

Hospital of the University of Occupational and Environmental Health, Japan, Kitakyushu-shi, Fukuoka-Ken

Hiroshima University Hospital, Hiroshima-shi, Hiroshima-Ken

Tonan Hospital, Sapporo-shi, Hokkaido

Japanese Red Cross Society Himeji Hospital, Himeji-shi, Hyogo-Ken

Kobe University Hospital, Kobe-shi, Hyogo-Ken

Kobe City Hospital Organization Kobe City Medical Center General Hospital, Kobe-shi, Hyogo-Ken

Kagawa University Hospital, Kita-gun, Kagawa-ken

St. Marianna University Hospital, Kawasaki-shi, Kanagawa-ken

Kitasato University Hospital, Sagamihara-shi, Kanagawa-Ken

Yokohama City University Medical Center, Yokohama-shi, Kanagawa-Ken

NHO Yokohama Medical Center, Yokohama-shi, Kanagawa-Ken

Japanese Red Cross Kumamoto Hospital, Kumamoto-shi, Kumamoto-Ken

Tohoku University Hospital, Sendai-shi, Miyagi-Ken

Nagasaki University Hospital, Nagasaki-shi, Nagasaki-Ken

NHO Osaka Minami Medical Center, Kawachinagano-shi, Osaka-Fu

Tazuke-kofukai Medical Research Institute Kitano Hospital, Osaka-shi, Osaka-Fu

Kindai University Hospital, Osakasayama-shi, Osaka-Fu

Osaka Medical and Pharmaceutical University Hospital, Takatsuki-shi, Osaka-Fu

Saitama Medical University Hospital, Iruma-gun, Saitama-Ken

Tokyo Medical and Dental University Hospital, Bunkyo-ku, Tokyo-To

St. Luke's International Hospital, Chuo-ku, Tokyo-To

Nihon University Itabashi Hospital, Itabashi-ku, Tokyo-To

Toho University Ohashi Medical Center, Meguro-ku, Tokyo-To

Toho University Omori Medical Center, Ota-ku, Tokyo-To

Keio University Hospital, Shinjuku-ku, Tokyo-To

Center Hospital of the National Center for Global Health and Medicine, Shinjuku-ku, Tokyo-To

Amsterdam UMC, Locatie VUMC, Amsterdam, Not set

Universitair Medisch Centrum Groningen, Groningen, Not set

UMC Utrecht, Utrecht, Not set

Centro Reumatologico, Caguas, Not set

S.C Centrul Medical de Diagnostic si Tratament Ambulator Neomed S.R.L, Brasov, Not set

S C Delta Health Care SRL, Bucuresti, Not set

Spitalul Clinic Judetean de Urgenta Cluj Napoca, Cluj-Napoca, Not set

S.C.Centrul Medical Unirea SRL, Iasi, Not set

Spitalul Judetean de Urgenta 'Sf. Ioan cel Nou' Suceava, Suceava, Not set

S.C Centrul Medical Unirea SRL, Targu Mures, Not set

Institute of Rheumatology, Belgrade, Not set

University Clinical Center of Serbia, Belgrade, Not set

Clinical Hospital Center Bezanijska kosa, Belgrade, Not set

Institute of Treatment and Rehabilitation 'Niska Banja', Niska Banja, Not set

Whipps Cross University Hospital, London, Greater London

Guy's Hospital, London, Greater London

Doncaster Royal Infirmary, Doncaster, South Yorkshire

Cannock Chase Hospital, Cannock, Staffordshire

Conditions: Lupus Erythematosus, Systemic

Learn More ›

Study to Evaluate KER-050 as a Monotherapy or in Combination With Ruxolitinib in Myelofibrosis

NCT05037760

Recruiting

This is a Phase 2, multicenter, open-label study to evaluate the safety and efficacy of KER-050 as monotherapy or in combination with ruxolitinib in participants with Myelofibrosis.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

01/23/2025

Locations: Fred Hutchinson Cancer Center, Seattle, Washington +46 locations

Fred Hutchinson Cancer Center, Seattle, Washington

Concord Hospital, Concord, New South Wales

The Tweed Hospital, Tweed Heads, New South Wales

Flinders Medical Centre, Woodville South, South Australia

St. Vincent's Hospital Melbourne, Fitzroy, Victoria

Royal Melbourne Hospital, Melbourne, Victoria

Ballarat Oncology & Hematology Service, Wendouree, Victoria

Hospital de Clinicas de Porto Alegre, Porto Alegre, Not set

IMV Pesquisa Cardiologica Sociedade Simples, Porto Alegre, Not set

Albert Einstein Sociedade Beneficente Israelita Brasiliera, São Paulo, Not set

Hospital Beneficencia Portuguesa de Sao Paulo, São Paulo, Not set

Hospital das Clínicas FMUSP: HC, São Paulo, Not set

Instituto de Ensino e Pesquisas Sao Lucas, São Paulo, Not set

CHU Amiens - Hopital Sud, Amiens, Not set

Hôpital Morvan, Brest, Not set

Hopital Prive Sevigne, Cesson-Sévigné, Not set

Centre Hospitalier Lyon Sud, Lyon, Not set

Institut de Cancerologie du Gard, Nîmes, Not set

Hopital de la Source - CHR Orleans, Orléans, Not set

Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari, Bari, Not set

Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi, Bologna, Not set

Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia, Not set

Azienda Ospedaliera Universitaria Careggi, Firenze, Not set

Ospedale Policlinico San Martino, Genova, Not set

ASST Grande Ospedale Metropolitano Niguarda, Milano, Not set

Fondazione IRCCS CA' Granda Ospedale Maggiore Policlinico, Milano, Not set

Arcispedale S. Maria Nuova Azienda Ospedaliera di Reggio Emilia, Reggio Emilia, Not set

Azienda Ospedaliera Universitaria Policlinico Umberto I, Roma, Not set

Policlinico Universitario Fondazione Agostino Gemelli, Roma, Not set

Azienda Socio Sanitaria Territoriale Sette Laghi, Varese, Not set

Azienda Ospedaliera Universitaria Integrata Verona, Verona, Not set

Gachon University Gil Medical Center, Incheon, Not set

Samsung Medical Center, Seoul, Not set

Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Not set

Soonchunhyang University Seoul Hospital, Seoul, Not set

Hospital Universitari Vall d'Hebron, Barcelona, Not set

Institut Català d'Oncologia Badalona - Hospital Universitari Germans Trias i Pujol, Barcelona, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Universitario La Princesa, Madrid, Not set

Hospital Universitario de Salamanca, Salamanca, Not set

Hospital Clinico Universitario de Valencia, Valencia, Not set

Hospital QuironSalud de Zaragoza, Zaragoza, Not set

Pilgrim Hospital, Boston, Not set

St. James Hospital, Leeds, Not set

Guy's Hospital, London, Not set

Hammersmith Hospital, London, Not set

University College London, London, Not set

Conditions: Myelofibrosis

Learn More ›

Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma

NCT05727020

Recruiting

Patients with early pancreatic cancer often have symptoms that could also be caused by many common benign conditions, or no symptoms at all. Jaundice, weight loss and pain are 'red flag' symptoms of pancreatic cancer that are linked to incurable disease. At the moment only patients with 'red flag' symptoms are urgently referred for diagnostic testing to find out if they have the cancer. As a result, late diagnosis is a common feature of pancreatic cancer. This leads to limited treatment options... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

01/23/2025

Locations: Imperial College Healthcare NHS Trust, London, Not set

Conditions: PDAC - Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer

Learn More ›

Imperial Prostate 9 - ATLAS (Approaches To Long-Term Active Surveillance)

NCT06280781

Recruiting

The goal of this intervention study is for patients on active surveillance for prostate cancer, to demonstrate that use of regular MRI scans is better able to detect cancer progression over 5 years compared to the current NICE defined strategy. Research Question P - In patients who are on active surveillance for low to medium risk prostate cancer, I - is the use of regular MRI scans C - compared to current NICE defined standard of care, O - better at detecting cancer progression with less cost... Read More

Gender:

MALE

Ages:

18 years and above

Trial Updated:

01/22/2025

Locations: Heatherwood Hospital, Ascot, Berkshire +2 locations

Conditions: Prostate Cancer

Learn More ›

Study of RP1 Monotherapy and RP1 in Combination With Nivolumab

NCT03767348

Recruiting

RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects with advanced and/or refractory solid tumors, to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D), as well as to evaluate preliminary efficacy.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

01/22/2025

Locations: University of Birmingham Alabama, Birmingham, Alabama +52 locations

University of Birmingham Alabama, Birmingham, Alabama

Banner MD Anderson Cancer Center, Gilbert, Arizona

Mayo Clinic, Phoenix, Arizona

Carti Cancer Center, Little Rock, Arkansas

UC San Diego, La Jolla, California

University of Southern California, Los Angeles, California

UCLA, Los Angeles, California

University of California, Irvine, Orange, California

University of California- San Francisco, San Francisco, California

Sylvester Comprehensive Cancer Center- University of Miami, Miami, Florida

University of Iowa-Cancer Center Research, Iowa City, Iowa

James Graham Brown Cancer Center- University of Louisville, Louisville, Kentucky

Mayo Clinic, Rochester, Minnesota

Atlantic Health System, Morristown, New Jersey

New York University Clinical Cancer Center, New York, New York

Weill Cornell Medical College, New York, New York

University of Rochester Medical Center, Rochester, New York

Duke Cancer Center, Durham, North Carolina

University of Cincinnati Medical Center, Cincinnati, Ohio

Providence Portland Medical Center, Portland, Oregon

MUSC Health, Charleston, South Carolina

West Cancer Center, Germantown, Tennessee

The University of Texas MD Anderson Cancer Center, Houston, Texas

Eccles Outpatient Care Center- Oncology Clinical Trials, Murray, Utah

Intermountain Cancer Center- Saint George Cancer Center, Saint George, Utah

Seattle Cancer Care Alliance- University of Washington, Seattle, Washington

University of Wisconsin-Carbone Cancer Center, Madison, Wisconsin

CHU Besancon - Hopital Jean Minjoz, Besançon, Not set

Institut Bergonié, Bordeaux, Not set

CHU Dijon, Dijon, Not set

Centre Léon Bérard Lyon, Lyon, Not set

Service de Dermatologie et Cancerologie Cutanee Hopital de la Timone, Marseille, Not set

CHU de Nice Hôpital l'Archet, Nice, Not set

Hôpital Saint Louis APHP, Paris, Not set

Institut Gustave Roussy, Villejuif, Not set

Charité (Campus Benjamin Franklin), Berlin, Not set

University Hospital Essen, Klinik für Dermatologie, Essen, Not set

University of Kiel (UKSH), Dep. of Dermatology, Kiel, Not set

Uniklinik Marburg, Marburg, Not set

Hospital Universitari Vall d'Hebron, Barcelona, Not set

Hospital Clinic Barcelona, Barcelona, Not set

Institut Catala D'Oncologia - Hospital Duran I, Barcelona, Not set

Clínica Universidad de Navarra (Madrid), Madrid, Not set

Hospital Universitario Virgen de la Arrixaca, Murcia, Not set

Clinica Universitaria de Navarra, Pamplona, Not set

Hospital Universitario Virgen del Rocio, Sevilla, Not set

Hospital General Universitario de Valencia, Valencia, Not set

University of Leeds- Teaching Hospital, Leeds, England

Oxford University Hospitals NHS Trust, Oxford, Oxfordshire

Beatson West of Scotland Cancer Center, Glasgow, Scotland

The Clatterbridge Cancer Centre NHS Foundation Trust, Bebington, Wirral

Royal Marsden Hospital, London, Not set

Southampton General Hospital, Southampton, Not set

Conditions: Cancer, Melanoma (Skin), Mismatch Repair Deficiency, Microsatellite Instability, Non-melanoma Skin Cancer, Cutaneous Melanoma, NSCLC

Learn More ›

Is Online Patient EducatioN Feasible in People with Patellofemoral Pain Whilst They Wait for Physiotherapy

NCT06744257

Recruiting

The primary aim is to determine if online patient education is a feasible intervention for people with PFP awaiting physiotherapy. The secondary aim is to provide outcome data to inform a future substantiative trial.

Gender:

ALL

Ages:

Between 18 years and 44 years

Trial Updated:

01/22/2025

Locations: East Suffolk and North Essex NHS Foundation Trust, Colchester, Not set

Conditions: Patello Femoral Syndrome

Learn More ›

Return to Golf After Orthopaedic Surgery

NCT05675618

Recruiting

The GOLF study is a multicenter, prospective study with the goal to investigate golfers' return to the sport following hip, knee or shoulder arthroplasty. The prevalence of return to golf, by level of returning to golf will be assessed at 6 weeks, 3 months, 6 months, and 12 months postoperatively. Patients who are active golfers undergoing joint replacement will be identified from outpatient clinics and pre-assessment clinics and given information about the study at least two weeks prior to surg... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

01/22/2025

Locations: Hospital for Special Surgery, New York, New York +1 locations

Conditions: Hip Osteoarthritis, Knee Osteoarthritis, Shoulder Osteoarthritis

Learn More ›

Observational Study of Venus P-Valve

NCT05835349

Recruiting

Real-world evidence, retrospective and prospective, non-randomized, multicenter observational study of VenusP-ValveTM System in treating moderate or greater pulmonary regurgitation with/without pulmonary stenosis in patients with native right ventricular outflow tract (RVOT).

Gender:

ALL

Ages:

Between 12 years and 70 years

Trial Updated:

01/21/2025

Locations: CHU Bordeaux, Pessac, Nouvelle-Aquitaine +9 locations

Conditions: Right Ventricular Outflow Tract Dysfunction

Learn More ›

Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs

NCT02493478

Recruiting

Advanced airway interventions are common high risk, high stakes events for children in intensive care units (ICU) and emergency departments (ED), with risk for life and health threatening consequences.

Gender:

ALL

Ages:

All

Trial Updated:

01/21/2025

Locations: Children's of Alabama at Birmingham, Birmingham, Alabama +86 locations

Children's of Alabama at Birmingham, Birmingham, Alabama

Phoenix Children's Hospital, Phoenix, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

Children's Hospital of Central California, Madera, California

University of Colorado Hospital, Aurora, Colorado

Yale New Haven Children's Hospital, New Haven, Connecticut

Yale-New Haven Children's Hospital, New Haven, Connecticut

Nemours Children's Health, Delaware, Wilmington, Delaware

Miami Children's Hospital, Miami, Florida

Emory University, Atlanta, Georgia

Children's Hospital of Atlanta - Scottish Rite, Atlanta, Georgia

Children's Hospital of Georgia, Augusta, Georgia

Northwestern Medicine Prentice Women's Hospital, Chicago, Illinois

Riley Hospital for Children, Indianapolis, Indiana

Beacon Children's Hospital, South Bend, Indiana

Kentucky Children's Hospital, Lexington, Kentucky

Norton Children's Hospital - University of Louisville, Louisville, Kentucky

Johns Hopkins Medicine, Baltimore, Maryland

University of Maryland, Baltimore, Maryland

Boston Children's Hospital, Boston, Massachusetts

Baystate Medical Center, Springfield, Massachusetts

Gillette Children's Specialty Health, Saint Paul, Minnesota

Children's Hospitals and Clinics of Minnesota, Saint Paul, Minnesota

Children's Hospital and Medical Center, Omaha, Nebraska

Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

Morristown Medical Center, Morristown, New Jersey

Albany Medical College, Albany, New York

The Children's Hospital at Montefiore, Bronx, New York

Oishei Children's Hospital, Buffalo, New York

Cohen Children's Medical Center, New Hyde Park, New York

New York Presbyterian Hospital Weill Cornell Medical College, New York, New York

University of Rochester at Golisano Children's Hospital, Rochester, New York

Stony Brook Children's Hospital, Stony Brook, New York

Maria Fareri Children's Hospital (West Chester Medical), Valhalla, New York

Duke Children's Hospital, Durham, North Carolina

WakeMed Health & Hospitals, Raleigh, North Carolina

WakeMed, Raleigh, North Carolina

Akron Children's Hospital, Akron, Ohio

Cincinnati Hospital Medical Center, Cincinnati, Ohio

Cleveland Clinic Childrens Hospital, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Oregon Health and Science University, Portland, Oregon

Children's Hospital - Penn State Hershey, Hershey, Pennsylvania

Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania

Hasbro Children's Hospital, Providence, Rhode Island

Le Bonheur Children's Hospital, Memphis, Tennessee

Dell Children's Medical Center - Ascension, Austin, Texas

Medical City Children's Hospital, Dallas, Texas

Baylor - Christus Children's - Main Hospital, Irving, Texas

Baylor - Christus Children's - Westover Hills, San Antonio, Texas

Baylor - Christus Children's - Stone Oak, San Antonio, Texas

The University of Vermont Children's Hospital, Burlington, Vermont

UVA Children's Hospital, Charlottesville, Virginia

Children's Hospital of Richmond at VCU, Richmond, Virginia

Seattle Children's Hospital, Seattle, Washington

University of Washington Medical Center, Seattle, Washington

University of Wisconsin - UnityPoint Meriter, Madison, Wisconsin

American Family Children's Hospital - University of Wisconsin, Madison, Wisconsin

Medical College of Wisconsin, Milwaukee, Wisconsin

University of Wisconsin - American Family Children's Hospital, Shorewood Hills, Wisconsin

Royal Brisbane and Women's Hospital, Herston, Not set

The Royal Children's Hospital Melbourne, Parkville, Not set

Medical University of Vienna (Medizinische Universität Wien), Vienna, Not set

Foothills Medical Centre, Calgary, Alberta

Alberta Children's Hospital, Calgary, Alberta

British Columbia Children's Hospital, Vancouver, British Columbia

CHU Sainte-Justine, Montreal, Quebec

CHU Sainte-Justine, Montréal, Quebec

The University of Manitoba, Winnipeg, Not set

University Hospital Schleswig-Holstein, Campus Luebeck, Children's Hospital, Luebeck, Not set

Aster Hospitals - India, Bengaluru, Karnataka

Rainbow Children's Hospital, Bangalore, Not set

Bambino Gesu, Roma, Not set

National Center for Child Health and Development, Setagaya-Ku, Tokyo

Hiroshima University, Hiroshima, Not set

Hyogo Prefectural Kobe Children's Hospital, Kobe, Not set

Aichi Children's Health and Medical Center, Obu, Not set

Saitama Children's Medical Center, Saitama, Not set

Jichi Medical University Hospital, Shimotsuke, Not set

Tokyo Metropolitan, Tokyo, Not set

Starship Children's Hospital, Auckland, Not set

KK Women's and Children's Hospital, Singapore, Not set

KK Women's & Children's Hospital, Singapore, Singapore, Not set

Cardiff & Vale University Health Board, Cardiff, Wales

Conditions: Failed or Difficult Intubation, Sequela, Intubation; Difficult, Intubation Complication

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Dermoscopy vs Standard Marking for the Completeness of Excision of Keratinocyte Skin Cancers: The ClearMark Trial

NCT06627036

Recruiting

What is the study about? This study aims to improve the success rate of removal surgery for a common type of skin cancer. We will compare two different methods of marking (drawing where to remove) the skin before removing the lump: the normal method using magnifying glasses and theatre lights, and our proposed method using a handheld magnifying device called a dermatoscope. Why is this study important? Skin cancer is the most common cancer in the UK. Currently, up to 10-11% of surgeries do not remove all of the cancer, which means patients may need more treatment. We do not know whether using a dermatoscope can help surgeons remove all of the cancer more often or not. If it does, it could prevent patients needing more surgery or time in hospital. What will happen during the study? A computer will randomly allocate each participant to marking using the normal method, or using a dermatoscope. The surgery will then proceed as usual. After the surgery, patients will be asked to fill in a simple questionnaire about their thoughts. We will collect data from patients' notes to monitor the success of the surgery and any more treatments needed. What will we measure? We will check participants records to see if the cancer was entirely removed. This is reported by a pathologist whenever a skin lump or bump is removed. In time, we will also look at 5-year recurrence of cancer, the need for additional treatments, any problems from the marking process, how happy patients are with the process, and the time it takes to perform the marking. What is the pilot for? The study will need many hundreds of patients to pick up a meaningful result. Before we commit to recruiting this many people, we want to make sure that the way we run the study is acceptable. This means looking at the number of people we recruit each week, how easy it is to collect their data after their operation, and whether there are any areas that we can't use a dermatoscope, such as the curves around the eye, nose and ears. We will run the study in a smaller number of people (around 200) before deciding whether we can commit to recruiting everyone. This will also give us the chance to see whether we can run the study in more than one hospital. Read Less

Gender:

ALL

Ages:

18 years and above

Trial Updated:

01/21/2025

Locations: Castle Hill Hospital, Hull, Not set

Conditions: Keratinocyte Skin Cancer

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The Effect of Ketone Esters on Forearm Glucose Metabolism

NCT06685913

Recruiting

Ketones are naturally produced by our body and can affect our blood sugar levels. Ketones could be important tool for treating disease or recovering from exercise. The purpose of this research is to determine if a ketone drink can increase sugar uptake in our muscles. This research will provide new knowledge about the regulation of blood sugar.

Gender:

ALL

Ages:

Between 18 years and 40 years

Trial Updated:

01/20/2025

Locations: Nutritional Physiology Research Unit, University of Exeter, Exeter, Devon

Conditions: Healthy

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