All Clinical Trials in United Kingdom

A listing of 3097 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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Mucopolysaccharidosis I (MPS I) Registry

NCT00144794

Recruiting

The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients receiving enzyme replacement therapy, such as Aldurazyme (Recombinant Human Alpha-L-Iduronidase), or other treatment modalities. The objectives of the Registry are: * To evaluate the lon... Read More

Gender:

ALL

Ages:

All

Trial Updated:

11/19/2024

Locations: Phoenix Children's Hospital- Site Number : 840003, Phoenix, Arizona +179 locations

Phoenix Children's Hospital- Site Number : 840003, Phoenix, Arizona

Arkansas Childrens Hospital- Site Number : 840109, Little Rock, Arkansas

Southern California Permanente Medical Group- Site Number : 840108, Los Angeles, California

USC Health Sciences Center Dept of Genetics- Site Number : 840082, Los Angeles, California

Children's Hospital Oakland- Site Number : 840029, Oakland, California

Children's Hospital of Orange County- Site Number : 840074, Orange, California

Stanford Unviersity MC Dept of Genetics- Site Number : 840022, Palo Alto, California

UC Davis MIND Institute- Site Number : 840010, Sacramento, California

Loma Linda University Children's Hospital- Site Number : 840117, San Bernardino, California

University of California at San Diego- Site Number : 840007, San Diego, California

University of California at San Francisco- Site Number : 840051, San Francisco, California

Children's Hospital IMD Clinic- Site Number : 840069, Aurora, Colorado

University of Colorado at Denver Genetics Site Number : 840068, Aurora, Colorado

Yale - Site Number : 840047, New Haven, Connecticut

Children's National Medical Center- Site Number : 840067, Washington, District of Columbia

University of Florida Dept of Genetics- Site Number : 840083, Gainesville, Florida

University of Florida Pediatrics Genetics- Site Number : 840121, Jacksonville, Florida

The Atwal Clinic- Site Number : 840112, Jacksonville, Florida

University Of Miami SOM- Site Number : 840006, Miami, Florida

Pediatric Endocrine Associates- Site Number : 840017, Tampa, Florida

Emory University School of Medicine- Human Genetics- Site Number : 840060, Decatur, Georgia

Ann and Robert Lurie Children's Hospital- Site Number : 840011, Chicago, Illinois

Rush University Medical Center Genetics- Site Number : 840079, Chicago, Illinois

Indianapolis University School of Medicine- Site Number : 840027, Indianapolis, Indiana

University of Iowa- Site Number : 840032, Iowa City, Iowa

University of Louisville- Genetics- Site Number : 840030, Louisville, Kentucky

Ochsner Medical Center - Site Number : 840120, New Orleans, Louisiana

John Hopkins- Site Number : 840044, Baltimore, Maryland

Massachusetts General Hospital-Genetics- Site Number : 840062, Boston, Massachusetts

Boston Children's Hospital- Site Number : 840093, Boston, Massachusetts

Baystate Health- Site Number : 840002, Springfield, Massachusetts

University of Michigan Pediatrics- Site Number : 840107, Ann Arbor, Michigan

Children's Hospital of Michigan- Site Number : 840066, Detroit, Michigan

Children's Health Care- Site Number : 840114, Minneapolis, Minnesota

University of Minnesota Medical Center Pediatrics- Site Number : 840076, Minneapolis, Minnesota

Washington University of St. Louis- Site Number : 840100, Saint Louis, Missouri

University of Nebraska Medical Center- Pediatrics- Site Number : 840084, Omaha, Nebraska

Children's Specialty Center of Nevada- Site Number : 840008, Las Vegas, Nevada

Joseph M. Sanzari Children's Hospital- Site Number : 840101, Hackensack, New Jersey

Atlantic Health System- Site Number : 840099, Morristown, New Jersey

St. Peter's University Hospital- Site Number : 840016, New Brunswick, New Jersey

St. Joseph's Children's Hospital- Site Number : 840057, Paterson, New Jersey

Northwell Health- Site Number : 840102, Manhasset, New York

New York University School Of Medicine- Site Number : 840040, New York, New York

Metropolitan Hospital Center- Site Number : 840110, New York, New York

University of Rochester Medical Center SOM- Site Number : 840105, Rochester, New York

State University of New York- Site Number : 840052, Syracuse, New York

Duke University Medical Center Genetics Dept- Site Number : 840037, Durham, North Carolina

Cincinnati Children's Hospital-Genetics- Site Number : 840041, Cincinnati, Ohio

UHCMC- Site Number : 840119, Cleveland, Ohio

Nationwide Children's Hospital- Site Number : 840091, Columbus, Ohio

LSD Data Registry Site LLC- Site Number : 840094, Dublin, Ohio

Oregon Health and Science University- Site Number : 840080, Portland, Oregon

Children's Hospital of Philadelphia HUP Medical Genetics- Site Number : 840089, Philadelphia, Pennsylvania

Children's Hospital of Philadelphia- Site Number : 840034, Philadelphia, Pennsylvania

University of Pittsburgh- Site Number : 840023, Pittsburgh, Pennsylvania

Rhode Island Hospital Genetics- Site Number : 840053, Providence, Rhode Island

Greenwood Genetcs- Site Number : 840055, Greenville, South Carolina

Baylor Research Center- Site Number : 840058, Dallas, Texas

University of Utah Health Hospital- Site Number : 840092, Salt Lake City, Utah

University of Virginia School of Medicine-Pediatrics- Site Number : 840078, Charlottesville, Virginia

Children's Hospital of the Kings Daughters- Site Number : 840072, Norfolk, Virginia

Seattle Children's Hospital- Site Number : 840028, Seattle, Washington

University Of Washington Medical Center- Site Number : 840059, Seattle, Washington

Multicare Health System ¿ Mary Bridge Childrens Hospital- Site Number : 840115, Tacoma, Washington

Children's Hospital of Wisconsin-Pediatrics- Site Number : 840054, Milwaukee, Wisconsin

Investigational Site Number : 153032, Ciudad Autónoma de Buenos Aires, Buenos Aires

Investigational Site Number : 153130, Buenos Aires, Not set

Investigational Site Number : 151069, Westmead, New South Wales

Investigational Site Number : 152096, Brisbane, Queensland

Investigational Site Number : 150944, Brussels, Not set

Investigational Site Number : 150517, Brussels, Not set

Investigational Site Number : 151668, Leuven, Not set

Investigational Site Number : 154008, Roeselare, Not set

Centro de Pesquisa Clínica Prédio 21, 2o andar Hospital de Clínicas de Porto Alegre- Site Number : 076001, Porto Alegre, Rio Grande Do Sul

Hospital e Maternidade Celso Pierro - PUC-Campinas- Site Number : 076007, Campinas, São Paulo

Instituto Fernandes Figueira - FIOCRUZ- Site Number : 076004, Rio de Janeiro, Not set

Instituto de Genética e Erros Inatos do Metabolismo - IGEIM- Site Number : 076002, São Paulo, Not set

Investigational Site Number : 124014, Calgary, Alberta

Investigational Site Number : 124002, Edmonton, Alberta

Investigational Site Number : 124011, Vancouver, British Columbia

Investigational Site Number : 124019, Winnipeg, Manitoba

Investigational Site Number : 124022, Moncton, New Brunswick

Investigational Site Number : 124021, London, Ontario

Investigational Site Number : 124006, Toronto, Ontario

Investigational Site Number : 124018, Montreal, Quebec

Investigational Site Number : 124001, Sherbrooke, Quebec

Investigational Site Number : 152003, Los Angeles, Not set

Investigational Site Number : 152001, Talcahuano, Not set

Investigational Site Number : 170001, Bogotá, Not set

Investigational Site Number : 1910001, Zagreb, Not set

Investigational Site Number : 150659, Praha 2, Not set

Investigational Site Number : 151229, København Ø, Not set

Investigational Site Number : 818002, Cairo, Not set

Investigational Site Number : 818001, Cairo, Not set

Investigational Site Number : 250004, Bordeaux, Not set

Investigational Site Number : 250001, BRON Cedex, Not set

Investigational Site Number : 250002, Marseille Cedex 05, Not set

Investigational Site Number : 250005, Paris Cedex 12, Not set

Investigational Site Number : 250003, Paris, Not set

Investigational Site Number : 250006, Vandœuvre-lès-nancy, Not set

Investigational Site Number : 151368, Hamburg, Not set

Investigational Site Number : 150031, Mainz, Not set

Investigational Site Number : 344001, Kowloon, Not set

Investigational Site Number : 3480005, Pécs, Not set

Investigational Site Number : 356003, Ahmedabad, Not set

Investigational Site Number : 356001, Kolkata, Not set

Investigational Site Number : 3560004, Secunderabad, Not set

Investigational Site Number : 356002, Vellore, Not set

Investigational Site Number : 360001, Jakarta, Not set

Investigational Site Number : 154161, Dublin, Not set

Investigational Site Number : 380002, Ancona, Not set

Investigational Site Number : 380004, Cusano Milanino, Not set

Investigational Site Number : 380009, Firenze, Not set

Investigational Site Number : 380003, Genova, Not set

Investigational Site Number : 380007, Milano, Not set

Investigational Site Number : 380005, Napoli, Not set

Investigational Site Number : 380008, Padova, Not set

Investigational Site Number : 380006, Roma, Not set

Investigational Site Number : 380001, Udine, Not set

Investigational Site Number : 392102, Nangoku-shi, Kochi

Investigational Site Number : 392101, Tokyo, Not set

Investigational Site Number : 151149, Seoul, Gyeonggi-do

Investigational Site Number : 154286, Changwon-si, Gyeongsangnam-do

Investigational Site Number : 153178, Yangsan-si, Gyeongsangnam-do

Investigational Site Number : 154148, Yangsan, Gyeongsangnam-do

Investigational Site Number : 153191, Daejeon, Not set

Investigational Site Number : 153225, Jeonnam, Not set

Investigational Site Number : 153180, Seoul, Not set

Investigational Site Number : 153196, Seoul, Not set

Investigational Site Number : 153192, Seoul, Not set

Investigational Site Number : 153212, Seoul, Not set

Investigational Site Number : 153222, Seoul, Not set

Investigational Site Number : 154225, Kuwait, Not set

Investigational Site Number : 4220004, Beirut, Not set

Investigational Site Number : 458001, Jalan Pahang, Not set

Investigational Site Number : 458002, Kuala Lumpur, Not set

Investigational Site Number : 151171, Amsterdam, Not set

Investigational Site Number : 152029, Rotterdam, Not set

Investigational Site Number : 154264, Lahore, Not set

Investigational Site Number : 154266, Lahore, Not set

Investigational Site Number : 608001, Manila, Not set

Investigational Site Number : 150575, Warszawa, Not set

Investigational Site Number : 6200002, Coimbra, Not set

Investigational Site Number : 154177, Cluj Napoca, Not set

Investigational Site Number : 643001, Moscow, Not set

Investigational Site Number : 643002, Moscow, Not set

Investigational Site Number : 682004, Makkah, Not set

Investigational Site Number : 682001, Qatif, Not set

Investigational Site Number : 702001, Singapore, Not set

Investigational Site Number : 703001, Bratislava, Not set

Investigational Site Number : 7520001, Stockholm, Not set

Investigational Site Number : 154093, Chiayi, Not set

Investigational Site Number : 152152, Hualien, Not set

Investigational Site Number : 152246, Kaohsiung City, Not set

Investigational Site Number : 152244, Kaohsiung, Not set

Investigational Site Number : 151534, New Taipei City, Not set

Investigational Site Number : 151500, Putz City, Chia-yi, Not set

Investigational Site Number : 151181, Taichung, Not set

Investigational Site Number : 151179, Taichung, Not set

Investigational Site Number : 153248, Tainan City, Not set

Investigational Site Number : 152153, Tainan City, Not set

Investigational Site Number : 151182, Taipei City, Not set

Investigational Site Number : 152321, Taipei, Not set

Investigational Site Number : 153158, Taoyuan City, Not set

Investigational Site Number : 764002, Bangkok, Not set

Investigational Site Number : 764003, Bangkok, Not set

Investigational Site Number : 764004, Bangkok, Not set

Investigational Site Number : 764001, Bangkok, Not set

Investigational Site Number : 764005, Khon Kaen, Not set

Investigational Site Number : 152287, Birmingham, Not set

Investigational Site Number : 154240, Birmingham, Not set

Investigational Site Number : 152156, Glasgow, Not set

Investigational Site Number : 151646, London, Not set

Investigational Site Number : 151123, London, Not set

Investigational Site Number : 150303, London, Not set

Investigational Site Number : 150455, Manchester, Not set

Investigational Site Number : 152361, Salford, Not set

Investigational Site Number : 154212, Hanoi, Not set

Investigational Site Number : 704002, Ho Chi Minh City, Not set

Conditions: Mucopolysaccharidosis I (MPS I)

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Symptom-specific Effects of Omega-3 Across Neurodevelopmental Symptoms

NCT06698588

Recruiting

Our study aims to determine whether omega-3 fatty acid supplementation can improve sleep, mood, and behavior in children with sleep problems and symptoms of Autism Spectrum Disorder (ASD), Attention-Deficit/Hyperactivity Disorder (ADHD), or both. By using a transdiagnostic approach-focusing on specific symptoms rather than diagnostic labels-we aim to identify which children may benefit most from omega-3 supplementation, thereby enhancing inclusivity. Many previous studies have excluded children... Read More

Gender:

ALL

Ages:

Between 5 years and 12 years

Trial Updated:

11/19/2024

Locations: FHMLS, Swansea, Not set

Conditions: Sleep, Autism or Autistic Traits, ADHD or ADHD Traits

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Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery

NCT04754022

Recruiting

TRICS-IV is an international, multi-centre, open-label randomized controlled trial of two commonly used transfusion strategies in moderate to high risk patients who are 65 years of age or younger undergoing cardiac surgery on cardiopulmonary bypass, using a superiority trial design.

Gender:

ALL

Ages:

Between 18 years and 65 years

Trial Updated:

11/18/2024

Locations: Maine Medical Center, Portland, Maine +53 locations

Maine Medical Center, Portland, Maine

The Cooper Health System, Camden, New Jersey

Columbia University, New York, New York

Thomas Jefferson University, Philadelphia, Pennsylvania

Royal Prince Alfred hospital, Camperdown, New South Wales

Prince of Wales Hospital, Randwick, New South Wales

Westmead Hospital, Westmead, New South Wales

Gold Coast University Hospital, Southport, Queensland

Flinders Medical Centre, Bedford Park, South Australia

Monash Health, Clayton, Victoria

St Vincent's Hospital Melbourne, Fitzroy, Victoria

Austin Health, Heidelberg, Victoria

Royal Adelaide Hospital, Adelaide, Not set

Royal Melbourne Hospital, Melbourne, Not set

Alfred Hospital, Prahran, Not set

University of Alberta Hospital, Edmonton, Alberta

Interior Health Kelowna General Hospital, Kelowna, British Columbia

Vancouver General Hospital, Vancouver, British Columbia

Saint John Regional Hospitall, Saint John, New Brunswick

Hamilton Health Sciences Centre / Hamilton General Hospital, Hamilton, Ontario

Kingston Health Sciences Centre, Kingston, Ontario

Health Sciences North Research Institute, Sudbury, Ontario

Sunnybrook Health Sciences Center, Toronto, Ontario

St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario

Toronto General Hospital, Toronto, Ontario

Montreal Heart Institute, Montreal, Quebec

Jewish General Hospital, Montreal, Quebec

Centre hospitalier de l'Université de Montréal, Montréal, Quebec

Hôpital Sacré-Cœur de Montréal, Montréal, Quebec

Institut universitaire de cardiologie et de pneumology de Québec - université Laval (IUCPQ-UL), Québec, Quebec

Hospital Universitario San Ignacio, Bogota, Not set

Fundacion Abood Shaio, Bogota, Not set

Fundacion Cardioinfantil, Bogota, Not set

Nasr City Health Insurance Hospital, Naşr, Cairo

Democritus University of Thrace, Alexandroupolis, Evros

EPIC Hospital, Ahmedabad, Gujrat

Windhoek Central Hospital, Windhoek, Khomas

Shahid Gangalal National Heart Center, Kathmandu, Not set

Emergency Institute of Cardiovascular Diseases, Bucharest, Not set

Saint-Petersburg State University Hospital, Saint Petersburg, Not set

National Heart Centre, Singapore, Not set

Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, Gauteng

Hospital de la Santa Creu I Sant Pau, Barcelona, Catalonia

Hospital General Universitari de Valencia, Valencia, Not set

Hospital Universitario La Fe Valencia, Valencia, Not set

University Hospital Basel, Basel, Not set

Inselspital, University Hospital Bern, University of Bern, Bern, Not set

University Hospital Leicester, Leicester, East Midlands

Basildon University Hospitals-Mid and South Essex NHS Trust, Basildon, Essex

University Hospital Southampton Foundation Trust, Southampton, Hampshire

University Hospitals Sussex NHS Foundation Trust, Brighton, Not set

University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, Not set

Royal Papworth Hospital NHS Foundation Trust., Cambridge, Not set

Manchester University NHS Foundation Trust, Wythenshawe, Not set

Conditions: Disorder, Heart, Postoperative, Cardiac Surgery

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A Placebo-controlled Trial of Chronic Total Occlusion Percutaneous Coronary Intervention for the Relief of Stable Angina

NCT05142215

Recruiting

ORBITA-CTO Pilot is a double blinded randomised placebo-controlled trial comparing the effects of chronic total occlusion percutaneous coronary intervention versus placebo on symptoms of angina in patients with background optimal medical therapy.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

11/18/2024

Locations: Essex Cardiothoracic Centre, Basildon, Essex +1 locations

Conditions: Stable Angina, Chronic Total Occlusion of Coronary Artery

Learn More ›

Merit WRAPSODY™ Endoprosthesis for Treatment of Stenosis or Occlusion (WRAP)

NCT05062291

Recruiting

The WRAP Study aims to expand and understand the safety and efficacy data on the WRAPSODY Endoprosthesis System in a real-world population.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

11/18/2024

Locations: Monash Health, Clayton, Not set +39 locations

Monash Health, Clayton, Not set

Austin Hospital, Heidelberg, Not set

Liverpool Hospital, Liverpool, Not set

Fiona Stanley Hospital, Murdoch, Not set

Sir Charles Gairdner Hospital, Nedlands, Not set

Princess Alexandra Hospital, Woolloongabba, Not set

Hospital Felicio Rocho, Belo Horizonte, Not set

Afya Hospital, Brasília, Not set

Hospital Santa Lucia, Brasília, Not set

Hospital Vera Cruz, Campinas, Not set

Instituto Pro Renal, Curitiba, Not set

Hospital Evangelico de Londrina, Londrina, Not set

Complexo Hospitalar de Niterói, Niterói, Not set

Parana Medical Research Center, Parnana, Not set

Hospital Mae de Deus, Porto Alegre, Not set

Real Hospital Português de Beneficência em Pernambuco, Recife, Not set

Impar Servicos Hospitalares S/A - Hospital Sao Lucas, Rio De Janeiro, Not set

Instituto Dor De Pesquisa E Ensino Regional Pernambuco, Rio De Janeiro, Not set

Rio de Janeiro State University, Rio de Janeiro, Not set

Hospital Da Bahia, Salvador, Not set

Hospital Santa Rita de Cassia, Sao Paulo, Not set

Centro Internacional de Pesquisa do Hospital Alemão Oswaldo Cruz, São Paulo, Not set

Instituto Dante Pazzanese de Cardiologia, São Paulo, Not set

Protestant Hospital Queen Elisabeth Herzberge, Berlin, Not set

University of Cologne, Cologne, Not set

The General University Hospital of Patras, Río, Not set

Shaare Zedek Medical Center, Jerusalem, Not set

IRCCS Policlinico San Matteo, Pavia, Not set

Maastricht UMC+, Maastricht, Not set

Te Toka Tumai Auckland, Auckland, Not set

Te Whatu Ora Health NZ Waitemata, Auckland, Not set

Te Whatu Ora Health NZ Waitaha Canterbury, Christchurch, Not set

Te Whatu Ora Health New Zealand Waitemata, Hamilton, Not set

CHUC - Centro Hospitalar e Universitário De Coimbra, Coimbra, Not set

Belfast City Hospital, Belfast Health and Social Care Trust, Belfast, Not set

Queen Elizabeth Hospital, University Hospital Birmingham, Birmingham, Not set

King's College Hospital, NHS Foundation Trust, London, Not set

Royal London Hospital, Barts Health NHS Trust, London, Not set

Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Not set

Royal Berkshire NHS Foundation Trust, Reading, Not set

Conditions: Venous Stenosis, Venous Occlusion

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The Use of the CUE1/CUE1+ in People With Parkinson's Disease and Related Disorders

NCT06174948

Recruiting

People with Parkinson's disease (PD) commonly experience a range of both motor (e.g., bradykinesia, rigidity, tremor, and postural instability) and non-motor (e.g., fatigue, psychiatric and behavioural disturbances, autonomic dysfunction, cognitive impairment, sleep dysfunction and olfactory loss) features. Currently, it is challenging to alleviate these symptoms with first-line treatment, the medications such as levodopa. The CUE1 is a non-invasive device, which is approved for sale in the UK m... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

11/18/2024

Locations: Queen Mary University of London, London, Not set

Conditions: Parkinson's Disease and Parkinsonism, Progressive Supranuclear Palsy, Dystonia, Multiple System Atrophy, Corticobasal Degeneration, Vascular Parkinsonism, Different Types of Tremor Including Essential Tremor, Orthostatic Tremor

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Effects of a Second-generation Mindfulness-based Intervention on Quality of Life, Pain Management, and Psycho-spiritual Wellbeing in Cancer Patients: A Randomised Controlled Trial

NCT06695234

Recruiting

Background This study explores the effectiveness of Meditation Awareness Training (MAT), a second-generation mindfulness-based intervention, in enhancing quality of life, pain management, and psycho-spiritual wellbeing among cancer patients. Existing research underscores the benefits of mindfulness-based interventions (MBIs) in alleviating psychological distress and improving overall quality of life for cancer patients. However, first-generation MBIs often exclude traditional Buddhist concepts such as impermanence and emptiness, Consequently, this can result in a superficial application that may not fully engage with the underlying causes of psychological distress or promote long-term spiritual and psychological growth. In contrast, second-generation MBIs like MAT aim to reintegrate these wisdom principles, potentially offering deeper psycho-spiritual benefits. By incorporating concepts like impermanence and emptiness, these interventions encourage a more holistic understanding and acceptance of life's challenges, fostering meaningful perspectives on illness and enhancing both spiritual and psychological wellbeing. This approach seeks to provide a more comprehensive and transformative experience for individuals, particularly those facing serious health challenges such as cancer. Aims The primary aim is to understand the effectiveness of MAT in individuals diagnosed with cancer. The study focuses on: Evaluating the impact of MAT on reducing psychological distress and enhancing pain management and quality of life. Exploring whether practising Buddhist wisdom concepts can foster meaningful perspectives on illness and life, thereby increasing spiritual wellbeing. Determining if MAT participation leads to the establishment of new daily practices and habits among cancer patients. Method The study employs a mixed-methods approach across three phases: Phase 1: A quantitative study using a randomised controlled trial (RCT) design. Participants will be divided into an intervention group (MAT) and a treatment-as-usual (TAU) control group. The effectiveness of MAT will be assessed using psychometric scales at multiple time points (baseline, week 4, week 9 post-intervention, and six-month follow-up). Importantly, participants in the TAU group will be offered the MAT intervention after the completion of the RCT, ensuring that all participants have access to the potential benefits of the intervention. Phase 2: A qualitative exploration using Interpretative Phenomenological Analysis (IPA) to gain insights into participants' lived experiences post-MAT intervention. This phase involves semi-structured interviews conducted at one month and six months post-intervention. Phase 3: A content analysis of diary entries collected from participants during the intervention to capture real-time reflections and experiences. Expected Outputs The study aims to provide empirical evidence on the effectiveness of MAT in improving psychological and spiritual wellbeing among cancer patients. It is expected to offer insights into how Buddhist wisdom can be integrated back into clinical mindfulness practices to enhance their impact. The findings could inform clinical practices and contribute to the development of more holistic mindfulness-based interventions for cancer care. Project Timelines Recruitment: Began in November 2024. Phase 1: The RCT is aimed to begin in the first quarter of 2025, with the intervention lasting 8 weeks, followed by data collection at specified time points. Phase 2: Conduct interviews at one month and six months post-intervention. Phase 3: Collect and analyse diary entries throughout the 8-week intervention. The entire study is structured to ensure comprehensive data collection and analysis, allowing for both quantitative and qualitative insights into the MAT intervention's impact on cancer patients. Read Less

Gender:

ALL

Ages:

18 years and above

Trial Updated:

11/15/2024

Locations: University of Derby, Derby, Derbyshire

Conditions: Cancer, Mindfulness-based Intervention, Meditation, Psychological Well-Being, Spiritual Wellbeing

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Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Cluster Headache

NCT03944876

Recruiting

Cluster headache is a primary headache condition characterized by clusters of one-sided, high-intensity pain attacks. The headache may be episodic or chronic. Treatment options are limited and their effects unsatisfactory. An important nerve pathway involved in the pain attacks has a switching station at the sphenopalatine ganglion (SPG) located in the depth of the facial bones. SPG is a known therapy target for cluster headache. The area can be identified on CT images, but is difficult to acces... Read More

Gender:

ALL

Ages:

Between 18 years and 85 years

Trial Updated:

11/15/2024

Locations: Praxisklinik Ulmenhof, Hamburg, Not set +4 locations

Conditions: Cluster Headache

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Sleep and Motor Learning in Stroke

NCT05746260

Recruiting

This study will explore whether sleep disruption in the sub-acute phase of stroke explains variation in clinical motor outcomes, and whether this relationship is mediated by variation in behavioural measures of overnight consolidation.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

11/15/2024

Locations: Wellcome Centre for Integrative Neuroimaging (WIN), Oxford, Not set

Conditions: Stroke

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Endoscopic Severity Image Recognition to Advance Research and Training in Inflammatory Bowel Disease (EVEREST - IBD)

NCT04867408

Recruiting

To develop and train a convolutional neural network to detect and characterize disease severity of inflammatory bowel disease during endoscopy

Gender:

ALL

Ages:

Between 16 years and 99 years

Trial Updated:

11/14/2024

Locations: Hull Royal Infirmary, Hull, East Yorkshire

Conditions: Inflammatory Bowel Disease 1

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QIST Collaborative - Arthroplasty Research Cohort (ARC) Study

NCT05824845

Recruiting

The ARC Study is a national observational cohort study to investigate patient reported and clinical outcomes after hip and knee replacements. The study has the following objectives: 1. To evaluate outcomes following hip and knee replacements. 2. To determine risk factors for adverse outcomes in primary hip and knee replacements. 3. To identify targets for future research and intervention in patients undergoing primary hip and knee replacements 4. To provide a resource from which to identify pot... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

11/14/2024

Locations: Northumbria Healthcare NHS Foundation Trust, Ashington, Not set

Conditions: Hip Arthritis, Knee Arthritis

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Effect of Chronic Feeding of Inulin And Methylcellulose on Colonic Fermentation

NCT06551961

Recruiting

To determine the effect on tolerance and gas production from chronic feeding of fermentable fibre (inulin) incorporated into a gel forming fibre (methylcellulose) compared with placebo (maltodextrin)

Gender:

ALL

Ages:

Between 18 years and 65 years

Trial Updated:

11/13/2024

Locations: Nottingham Digestive Disease Centre, Nottingham, Nottinghamshire +1 locations

Conditions: Irritable Bowel Syndrome

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