Pulmonary and Cardiac Effects of E-Cigarette Use in Pulmonary Patients Who Smoke Cigarettes
NCT05610514
Recruiting
The purpose of this study is to compare the effects of e-cigarettes and continued smoking on pulmonary and cardiac outcomes in a population with established pulmonary disease.
Gender:
All
Ages:
40 years and above
Trial Updated:
11/27/2023
Locations: Vermont Center on Behavior and Health, Burlington, Vermont
Conditions: Chronic Obstructive Pulmonary Disease, Chronic Bronchitis, Emphysema, Asthma-COPD Overlap Syndrome
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Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (KALOS)
NCT04609878
Recruiting
This is a variable length study to evaluate the efficacy and safety of budesonide/glycopyrronium/formoterol inhaler in adults and adolescents with severe asthma inadequately controlled with standard of care
Gender:
All
Ages:
Between 12 years and 80 years
Trial Updated:
10/26/2023
Locations: Research Site, Burlington, Vermont
Conditions: Asthma
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Self-regulation for Older Adults With Asthma Through Remote Education
NCT05722834
Recruiting
This research is studying whether changing an individual's behaviors may have an impact as a treatment or outcome for asthma. The purpose of this study is to implement and evaluate an asthma self-management intervention through multiple locations in the United States that is tailored to the challenges older adults face and is based on an individual behavioral theory of change. Eligible participants will be enrolled and participate for six weeks in the SOAR intervention.
Gender:
All
Ages:
60 years and above
Trial Updated:
08/01/2023
Locations: University of Vermont, Burlington, Vermont
Conditions: Asthma
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Medication Adherence With Telehealthcare Medication Therapy Management
NCT03978936
Recruiting
Improving Medication Adherence with Telehealthcare Medication Therapy Management to Change Health Outcomes in Adolescents and Young Adults with Asthma (MATCH) is a multi-center, randomized parallel group study targeted to an at-risk population of Adolescents and Young Adults (AYA) with uncontrolled asthma who have poor adherence with prescribed Inhaled corticosteroid (ICS) therapy.
Gender:
All
Ages:
Between 12 years and 35 years
Trial Updated:
06/08/2023
Locations: Vermont Lung Center at The University of Vermont, Colchester, Vermont
Conditions: Uncontrolled Asthma, Young Adults
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Increased Lung Volume as Controller Therapy for Asthma
NCT02953431
Recruiting
This is an early phase clinical trial to test the efficacy of elevating lung volume with positive expiratory pressure (CPAP) as a controller therapy for asthma in patients with a BMI ≥ 30 kg/m2. There will be two phases to this trial. Phase I: In the first phase we will determine the optimal duration of CPAP that is effective as a controller therapy in asthma. Up to 9 participants will complete this this phase. Phase II: The 2nd phase will be a randomized double-blinded controlled trial of... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/17/2023
Locations: Vermont Lung Center, Colchester, Vermont
Conditions: Asthma
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MitoQ for the Treatment of Metabolic Dysfunction in Asthma
NCT04026711
Recruiting
A 14-week, randomized, placebo-controlled, double-masked clinical trial in 40 obese patients with poorly controlled asthma. The intervention is Mitoquinol (MitoQ) versus placebo. The primary aim of this pilot study is to determine if MitoQ improves airway reactivity in obese patients with asthma.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/26/2023
Locations: University of Vermont, Burlington, Vermont
Conditions: Asthma, Obesity
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