There are currently 587 clinical trials in Richmond, Virginia looking for participants to engage in research studies. Trials are conducted at various facilities, including Virginia Commonwealth University, Virginia Commonwealth University/Massey Cancer Center, GSK Investigational Site and Virginia Cancer Institute. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
The Impact of Oral Ethanol and Vaped Ethanol on the Evaluation of Impairment
NCT04522973
Recruiting
The purpose of this research study is to find out about ethanol-containing e-cigarettes impact ethanol breath tests, field sobriety tests, or other tests of sobriety. Ethanol is a common part of e-cigarette liquids.
Gender:
All
Ages:
Between 21 years and 55 years
Trial Updated:
12/13/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Electronic Cigarette Use
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Feasibility and Acceptability of Using Weighted Blankets to Prevent and /or Mitigate Delirium
NCT06161480
Recruiting
The use of weighted blankets to avert or alleviate Delirium in Adult ICU patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/05/2023
Locations: VCU Health Systems, Richmond, Virginia
Conditions: Delirium
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A Study of Zetomipzomib (KZR-616) in Patients With Autoimmune Hepatitis (PORTOLA)
NCT05569759
Recruiting
This is a Phase 2a, multi-center, placebo-controlled study in which patients with autoimmune hepatitis will receive zetomipzomib or placebo in addition to standard-of-care for 24 weeks; an optional open-label extension period allows patients to receive zetomipzomib (KZR-616) for an additional 24 weeks of treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/04/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Autoimmune Hepatitis
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Sickle Cell Disease and CardiovAscular Risk - Red Cell Exchange Trial (SCD-CARRE)
NCT04084080
Recruiting
The SCD-CARRE trial is a Phase 3, prospective, randomized, multicenter, controlled, parallel two-arm study aimed to determine if automated exchange blood transfusion and standard of care administered to high mortality risk adult SCD patients reduces the total number of episodes of clinical worsening of SCD requiring acute health care encounters (non-elective infusion center/ER/hospital visits) or resulting in death over 12 months as compared with standard of care.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/04/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Sickle Cell Disease
Register for Updates
A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)
NCT04951219
Recruiting
A 52-Week, Multi-center, Open-label, Active Treatment Extension Study to Evaluate Safety and Tolerability of Once Daily, Oral Administration of Resmetirom (MGL-3196)
Gender:
All
Ages:
18 years and above
Trial Updated:
11/28/2023
Locations: Bon Secours Liver Institute of Richmond, Richmond, Virginia +2 locations
Conditions: Non-Alcoholic Fatty Liver Disease
Register for Updates
Children's Bipolar Network Treatment Trial I
NCT05427123
Recruiting
This is a naturalistic treatment and follow-up study of youth with bipolar spectrum disorders (BSDs) across four US sites of The Childhood Bipolar Network (CBN). CBN sites have expertise in diagnosing, assessing, and treating BSDs in youth. The primary aims of this study are to (1) identify and reliably diagnose youth (ages 9 to 19 yrs) with full bipolar disorder (BD) and BSDs, and (2) examine predictors (e.g., mood instability, inflammatory marker C-reactive protein) of clinical outcome over a... Read More
Gender:
All
Ages:
Between 9 years and 19 years
Trial Updated:
11/22/2023
Locations: Virginia Commonwealth University Medical Center, Richmond, Virginia
Conditions: Bipolar Disorder, Bipolar I Disorder, Bipolar II Disorder, Other Specified Bipolar and Related Disorder, Mood Instability, Child Mental Disorder, Adolescent - Emotional Problem
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Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion
NCT05976646
Recruiting
The overall goal of this project is to collect initial human data on the effects of novel compounds on safety (interactions with an opioid drug, e.g., buprenorphine) and early efficacy signals (subjective effects on negative affect, craving, and opioid withdrawal) in OUD subjects currently in MOUD treatment with buprenorphine.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
11/20/2023
Locations: CARI Research Clinic- VCU Institute for Drug and Alcohol Studies, Richmond, Virginia
Conditions: Addiction, Opioid Use, Substance Use Disorders, Opioid Use Disorder
Register for Updates
Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies
NCT04924322
Recruiting
The goal of the CRETE Studies is to investigate the newly identified age-dependent heterogeneity in the efficacy of enoxaparin in reducing the risk of central venous catheter-associated deep venous thrombosis in critically ill children.
Gender:
All
Ages:
17 years and below
Trial Updated:
11/20/2023
Locations: Children's Hospital of Richmond, Richmond, Virginia
Conditions: Deep Venous Thrombosis
Register for Updates
Left vs Left Randomized Clinical Trial
NCT05650658
Recruiting
The investigators aim to prospectively test the comparative effectiveness of His or Left bundle branch pacing in relation to patient centered outcomes (quality of life, physical activity, heart failure hospitalization, mortality) and comparative safety in relation to device-related complications and re-interventions (e.g., lead dislodgement, infection) relative to standard of care biventricular pacing in patients with heart failure due to left ventricular systolic dysfunction (LVEF≤50%) and with... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/19/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Heart Failure, Heart Failure With Reduced Ejection Fraction, AV Block, LBBB, RBBB, Intraventricular Conduction Delay, Pacing-Induced Cardiomyopathy
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Niraparib and Neratinib in Advanced Solid Tumors With Expansion Cohort in Advanced Ovarian Cancer
NCT04502602
Recruiting
To determine the recommended phase 2 dose (RP2D) of niraparib and neratinib in combination in patients with advanced solid tumors during Phase 1. To evaluate clinical benefit (≥4-month progression-free survival [PFS]) of niraparib and neratinib in patients with platinum-resistant ovarian cancer in Phase 1b.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/15/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Advanced Solid Tumor, Ovarian Cancer
Register for Updates
Cryospray Therapy for Benign Airway Stenosis
NCT06085209
Recruiting
This is a clinical evaluation to assess the effectiveness of cryospray therapy used in addition to current standard of care endoscopic therapies in preventing short term recurrent airway stenosis with a multicentric outcome evaluation. The investigators hypothesize that the addition of SCT to standard endoscopic treatment of benign airway stenosis will result in decreased stenosis recurrence at 6 months as estimated by quantitative radiologic assessment of the stenotic volume.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/14/2023
Locations: Virgnia Commonwealth University, Richmond, Virginia
Conditions: Stenosis Trachea
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An Observational Study of Patients With Chronic Hepatitis B (CHB) Infection
NCT03692897
Recruiting
The TARGET-HBV study engages an observational research design to conduct a comprehensive review of outcomes for patients with CHB infection. The initial phase of the study that enrolled patients treated with tenofovir alafenamide (TAF) was successfully completed. The current protocol (Amendment 1) describes the second phase of the study that will engage research activities for patients being managed for CHB in usual clinical practice in the US and Canada. The study addresses important clinical q... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/13/2023
Locations: Bon Secours Liver Institute of Richmond, Richmond, Virginia +1 locations
Conditions: Hepatitis B, Hepatitis, Liver Diseases
Register for Updates