There are currently 603 clinical trials in Richmond, Virginia looking for participants to engage in research studies. Trials are conducted at various facilities, including Virginia Commonwealth University, Virginia Commonwealth University/Massey Cancer Center, Virginia Cancer Institute and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Total Neoadjuvant Therapy With mFOLFOX and Short-course Radiation in Resectable Rectal Cancer
NCT04643366
Recruiting
This is phase 2 trial of neoadjuvant therapy and short-course radiotherapy in resectable rectal cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/20/2025
Locations: Virginia Cancer Institute, Richmond, Virginia +1 locations
Conditions: Rectal Cancer
Register for Updates
Treating Heart Dysfunction Related to Cancer Therapy With Sacubitril/Valsartan
NCT05194111
Recruiting
To determine feasibility of recruitment and tolerability of treatment with sacubitril-valsartan among adult age survivors of cancer diagnosed at or before age 39 who have stage B heart failure.
Gender:
ALL
Ages:
Between 18 years and 120 years
Trial Updated:
02/20/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Heart Failure, Heart Dysfunction
Register for Updates
ASHBY: Accelerated Super-Hypofractionated Breast Brachytherapy
NCT06185205
Recruiting
The purpose of this study is to compare any good and bad effects of giving radiation treatment for breast cancer in 3 treatments over about 2 days.
Gender:
FEMALE
Ages:
Between 45 years and 79 years
Trial Updated:
02/20/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Breast Cancer
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Behavioral Exercise TRaining for Men Undergoing Androgen Depr Therapy for Prostate Ca
NCT06250751
Recruiting
To refine a remote behavioral exercise training intervention for testing in a larger randomized trial.
Gender:
MALE
Ages:
Between 41 years and 85 years
Trial Updated:
02/20/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Prostate Cancer
Register for Updates
Immune Registry for BK in Kidney Transplant Recipients
NCT06538961
Recruiting
Kidney transplantation (KT) is the best treatment modality available to date for patients with advanced kidney disease and the success of KT is dependent on maintaining a selective intricate balance between the risk of rejection and infections in KT recipients. BK virus is an important clinical infection affecting the post-transplant outcomes in KT recipients. BK nephropathy can affect 8-15% of patients after KT causing acute kidney injury, increased risk of rejection and fibrosis leading to add... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/20/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: BK Virus Infection, Kidney Transplant; Complications
Register for Updates
GZ17-6.02 in Advanced CRPC After Progression on Anti-Androgen Therapy
NCT06636123
Recruiting
The purpose of this clinical trial is to determine if GZ17-6.02 delays progression of castration-resistant prostate cancer.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
02/20/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Castration-resistant Prostate Cancer
Register for Updates
Research Participation With Transgender and Gender-Diverse Youth
NCT05927350
Recruiting
Research has historically excluded the participation of transgender and gender-diverse people. The purpose of this research study is to find out about what goes into a transgender and gender-diverse youth's decision to participate in research. The results of this study will be used to improve access to research for transgender and gender-diverse youth and therefore, improve the representation of transgender and gender-diverse youth as research participants in research.
Gender:
ALL
Ages:
Between 15 years and 21 years
Trial Updated:
02/17/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Transgender Persons
Register for Updates
Implantation of BioSphincter TM for Treatment of Severe Passive Fecal Incontinence
NCT05616208
Recruiting
This is first-in-human prospective Phase I study of the immediate and long-term safety of an implanted internal anal sphincter (IAS) bioengineered from autologous cells to treat subjects with severe passive FI who have failed standard treatments.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/14/2025
Locations: Virginia Commonwealth University Health Main Hospital (VCU), Richmond, Virginia
Conditions: Fecal Incontinence
Register for Updates
A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
NCT04094610
Recruiting
Phase 1 will evaluate the safety and tolerability at different dose levels of repotrectinib in pediatric and young adult subjects with advanced or metastatic malignancies harboring anaplastic lymphoma kinase (ALK), receptor tyrosine kinase encoded by the gene ROS1 (ROS1), or neurotrophic receptor kinase genes encoding TRK kinase family (NTRK1-3) alterations to estimate the Maximum Tolerated Dose (MTD) or Maximum Administered Dose (MAD) and select the Pediatric Recommended Phase 2 Dose (RP2D). P... Read More
Gender:
ALL
Ages:
25 years and below
Trial Updated:
02/12/2025
Locations: Children's Hospital of Richmond at VCU, Richmond, Virginia
Conditions: Locally Advanced Solid Tumors, Metastatic Solid Tumors, Lymphoma, Primary CNS Tumors
Register for Updates
Left vs Left Randomized Clinical Trial
NCT05650658
Recruiting
The investigators aim to prospectively test the comparative effectiveness of His or Left bundle branch pacing in relation to patient centered outcomes (quality of life, physical activity, heart failure hospitalization, mortality) and comparative safety in relation to device-related complications and re-interventions (e.g., lead dislodgement, infection) relative to standard of care biventricular pacing in patients with heart failure due to left ventricular systolic dysfunction (LVEF≤50%) and with... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/12/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Heart Failure, Heart Failure With Reduced Ejection Fraction, AV Block, LBBB, RBBB, Intraventricular Conduction Delay, Pacing-Induced Cardiomyopathy
Register for Updates
Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of CNP-106 in Subjects with Myasthenia Gravis
NCT06106672
Recruiting
Phase 1b/2a First-in-Human (FIH) clinical trial to assess the safety, tolerability, pharmacodynamics (PD), and efficacy of multiple ascending doses of CNP-106.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/12/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Myasthenia Gravis, Generalized Myasthenia, AChR Myasthenia Gravis, MuSK MG
Register for Updates
Oral Health In Cirrhosis of the Liver (ORACLE)
NCT06052150
Recruiting
The goal of this observational study is to learn about dental evaluation and periodontal cleaning along with scheduled follow -up on the dental health and overall health of patients with cirrhosis and also to determine what barrier(s) if any exist to improve oral health in this population.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/10/2025
Locations: Hunter Holmes McGuire VA Medical Center, Richmond, Virginia +1 locations
Conditions: Cirrhosis, Periodontal Diseases
Register for Updates