All Clinical Trials

A listing of 23094 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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Featured Trial

Paid Clinical Studies Nationwide

Recruiting

Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

Healthy

Healthy Volunteer Study

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* Compensation for time may be available

Featured Trial

Chronic Cough Research Study

Recruiting

Are you tired of living with chronic cough? Our research study is now looking to enroll people from all backgrounds to help research potential new treatment options for chronic cough.
You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you!

Conditions:

Chronic Cough

Refractory or Unexplained Chronic Cough

Cough

Asthma

Sinusitis

Learn More

Featured Offer

Lose Weight with GLP-1 Medications

Recruiting

Policy Lab has partnered with CareGLP to offer trusted access to GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.

GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.

As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.

Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

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64Cu-SAR-bisPSMA Positron Emission Tomography: A Phase 3 Study of Participants With Biochemical Recurrence of Prostate Cancer

NCT06970847

Recruiting

The aim for this study is to investigate the ability of 64Cu-SAR-bisPSMA PET/CT to detect recurrence of prostate cancer

Gender:

MALE

Ages:

18 years and above

Trial Updated:

06/09/2025

Locations: XCancer, Omaha, Nebraska

Conditions: Prostate Cancer, Prostate Cancer Patients With Detectable PSA Following Prostatectomy, Prostate Cancer Recurrent, Prostate Cancer Patients Who Have Brachytherapy Seed Implant, Prostate Cancer Patients Treated by Radiotherapy, Cryotherapy

Learn More ›

Buspirone for the Treatment of Traumatic Brain Injury (TBI) Irritability and Aggression

NCT01821690

Recruiting

The purpose of this study is to improve behavior control displayed by persons with traumatic brain injury by assessing effectiveness of treatments for post-TBI irritability and aggression.

Gender:

ALL

Ages:

Between 18 years and 70 years

Trial Updated:

06/09/2025

Locations: Indiana University and Rehabilitation Hospital of Indiana, Indianapolis, Indiana

Conditions: Traumatic Brain Injury

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Alcohol Treatment Outcomes Following Early vs. Standard Liver Transplant for SAH

NCT03845205

Recruiting

Given the severe consequences of alcohol relapse following liver transplantation for alcoholic hepatitis (AH-LT), it is critical to accurately identify alcohol use and implement alcohol interventions early in the post-transplant period to optimize patient outcomes. The proposed randomized clinical trial will examine the implementation and effects of integrated, person- and computer-delivered alcohol treatment compared to standard care on alcohol use (assessed by self-report and biomarker), mood,... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/09/2025

Locations: Johns Hopkins University School of Medicine, Baltimore, Maryland

Conditions: Alcohol Use Disorder, Alcoholic Hepatitis

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Long-term Impact of Infection With Novel Coronavirus (COVID-19)

NCT04362150

Recruiting

LIINC is a study of volunteers who were previously infected with SARS-CoV-2 (also known as novel coronavirus or COVID-19) who have recovered from acute infection. The study is designed to provide a specimen bank of samples with carefully characterized clinical data. LIINC specimens will be used to examine multiple questions involving the virologic, immunologic, and host factors involved in COVID-19, with a focus on understanding variability in the long-term immune response between individuals.

Gender:

ALL

Ages:

Between 18 years and 100 years

Trial Updated:

06/09/2025

Locations: Zuckerberg San Francisco General Hospital (ZSFG), San Francisco, California

Conditions: COVID

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Safety and Efficacy of the Sentinel Cerebral Protection Device in Atrial Fibrillation Ablation

NCT04685317

Recruiting

The purpose of the study is to see if the Sentinel® Cerebral Protection System may prevent occurrence of stroke during an ablation procedure for atrial fibrillation (AF). The secondary purpose of this study is to study if cognitive function after AF ablation differs between those treated with the Sentinel cerebral protection device and those who do not receive the device.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/09/2025

Locations: Mayo Clinic in Rochester, Rochester, Minnesota

Conditions: Arrhythmia, Atrial Fibrillation

Learn More ›

Mindfulness-Based Intervention for Latino Cancer Patients and Their Caregivers

NCT04870788

Recruiting

This clinical trial develops effective and appropriate mindfulness-based interventions that help meet the needs of Latino cancer patients and their family caregivers. Mindfulness-based interventions focus on building awareness of thoughts, emotions/feelings, and the sensations. This study may help improve mental well-being and reduce stress and anxiety associated with having cancer or with a family member's cancer diagnosis.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/09/2025

Locations: M D Anderson Cancer Center, Houston, Texas

Conditions: Advanced Malignant Solid Neoplasm

Learn More ›

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

NCT05125302

Recruiting

Migraine is a common neurological disorder typically characterized by attacks of throbbing, moderate to severe headache, often associated with nausea, vomiting, and sensitivity to light and sound. Migraine is extremely common and disabling in children. The purpose of this study is to evaluate how safe and effective ubrogepant is in the acute treatment of migraine in children and adolescents. Ubrogepant is a drug approved for the acute treatment of migraine in adults. Children and adolescents (aged 6-17 years) with a history of migraine will be enrolled. The study will include 2 cohorts of participants - PK Cohort and Main Study (non-PK cohort). Participants aged 6-11 years in the PK Cohort will receive Dose A or Dose B of Ubrogepant for PK analysis to determine dose selection for the main study. In the main study, after dose selection, children aged 6-11 years will be randomized to receive either low or high dose of Ubrogepant or placebo. There is a 1 in 3 chance that a participant will be assigned to placebo. Adolescents aged 12-17 years will be randomized to receive either low or high dose of Ubrogepant or placebo with a 1 in 3 chance of placebo assignment. For qualifying migraine attacks, participants will receive oral tablets of the double-blind study intervention. There will be an option to take a second dose of double-blind study intervention (identical to initial dose), or rescue medication, at least 2 hours after the initial dose, for headache of moderate/severe intensity. Around 1059 participants will be enrolled in the study in approximately 120 sites in the United States. The study duration will be up to 6 months. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires. Read Less

Gender:

ALL

Ages:

Between 6 years and 17 years

Trial Updated:

06/09/2025

Locations: Rehabilitation & Neurological Services /ID# 229969, Huntsville, Alabama +111 locations

Rehabilitation & Neurological Services /ID# 229969, Huntsville, Alabama

The Center for Clinical Trials - Saraland /ID# 231546, Saraland, Alabama

Preferred Research Partners /ID# 230725, Little Rock, Arkansas

Advanced Research Center /ID# 227962, Anaheim, California

Neuro Pain Medical Center /ID# 227966, Fresno, California

Alliance for Research Alliance for Wellness /ID# 230546, Long Beach, California

Children's Hospital Los Angeles /ID# 230596, Los Angeles, California

Excell Research, Inc /ID# 230899, Oceanside, California

Paradigm Clinical Research - San Diego /ID# 269608, San Diego, California

Lumos Clinical Research Center /ID# 231267, San Jose, California

Pacific Clinical Research Management Group /ID# 231636, Upland, California

Sunwise Clinical Research /ID# 230971, Walnut Creek, California

Children's Hospital Colorado - Aurora /ID# 231879, Aurora, Colorado

IMMUNOe Research Centers /ID# 230879, Centennial, Colorado

MCB Clinical Research Centers /ID# 231625, Colorado Springs, Colorado

New England Institute for Clinical Research /ID# 230635, Stamford, Connecticut

Emerson Clinical Research Inst /ID# 231693, Washington, District of Columbia

Encore Medical Research of Boynton Beach LLC /ID# 246833, Boynton Beach, Florida

Gulf Coast Clinical Research Center /ID# 230020, Fort Myers, Florida

Sarkis Clinical Trials /ID# 227956, Gainesville, Florida

Northwest Florida Clinical Research Group, LLC /ID# 231069, Gulf Breeze, Florida

A.G.A Clinical Trials /ID# 230554, Hialeah, Florida

Encore Medical Research /ID# 245682, Hollywood, Florida

Advanced Research Institute of Miami /ID# 230292, Homestead, Florida

Auzmer Research /ID# 239251, Lakeland, Florida

Columbus Clinical Services, Llc /Id# 230880, Miami, Florida

My Preferred Research LLC /ID# 227886, Miami, Florida

Neurology & Pain Medicine /ID# 240168, Miami, Florida

Medical Research Group of Central Florida /ID# 231632, Orange City, Florida

Clinical Associates of Orlando, LLC /ID# 272619, Orlando, Florida

Suncoast Clinical Research - Palm Harbor /ID# 229337, Palm Harbor, Florida

Asclepes Research Centers - Spring Hill /ID# 229815, Spring Hill, Florida

University of South Florida- Neuroscience Institute /ID# 229324, Tampa, Florida

Encore Medical Research - Weston /ID# 246809, Weston, Florida

Pediatric Neurology and Epilepsy Specialists /ID# 229967, Winter Park, Florida

Treken Primary Care /ID# 240586, Atlanta, Georgia

Rare Disease Research, LLC /ID# 231046, Atlanta, Georgia

Clinical Integrative Research Center of Atlanta (CIRCA) /ID# 231134, Atlanta, Georgia

Coastal Georgia Child Neurology /ID# 231409, Brunswick, Georgia

CenExcel iResearch LLC /ID# 227903, Decatur, Georgia

Velocity Clinical Research - Savannah /ID# 228992, Savannah, Georgia

Sleep Care Research Institute d/b/a Clinical Research Institute /ID# 231738, Stockbridge, Georgia

Velocity Clinical Research - Boise /ID# 231871, Meridian, Idaho

Chicago Headache Center & Research Institute /ID# 248625, Chicago, Illinois

Accellacare - McFarland Clinic /ID# 229789, Ames, Iowa

College Park Family Care Center Overland Park /ID# 231456, Overland Park, Kansas

Psychiatric Associates /ID# 230872, Overland Park, Kansas

Alliance for Multispecialty Research (AMR) - Wichita West /ID# 234126, Wichita, Kansas

University of Kentucky Chandler Medical Center /ID# 230827, Lexington, Kentucky

Pharmasite Research, Inc. /ID# 227908, Baltimore, Maryland

Minneapolis Clinic of Neurology - Burnsville /ID# 232551, Burnsville, Minnesota

MediSync Clinical Research Hattiesburg Clinic /ID# 233326, Petal, Mississippi

Proven Endpoints LLC /ID# 239513, Ridgeland, Mississippi

Sharlin Health Neuroscience Research Center /ID# 229523, Ozark, Missouri

Cognitive Clinical Trials (CCT) - Papillion /ID# 232552, Papillion, Nebraska

Healthy Perspectives - Innovative Mental Health Services, PLLC /ID# 230312, Nashua, New Hampshire

Hunterdon Neurology /ID# 245648, Annandale, New Jersey

Goryeb Children's Hospital /ID# 229507, Morristown, New Jersey

CVS HealthHUB - Runnemede /ID# 234233, Runnemede, New Jersey

Dent Neurologic Institute - Amherst /ID# 231182, Amherst, New York

Bioscience Research /ID# 232159, Mount Kisco, New York

Modern Migraine MD /ID# 258081, New York, New York

North Suffolk Neurology /ID# 230956, Port Jefferson Station, New York

SUNY Upstate Medical University /ID# 239898, Syracuse, New York

CVS HealthHUB - Charlotte /ID# 239530, Charlotte, North Carolina

OnSite Clinical Solutions, LLC - Hickory /ID# 227994, Hickory, North Carolina

Patient Priority Clinical Sites, LLC /ID# 238485, Cincinnati, Ohio

University Of Cincinnati Medical Center /ID# 231199, Cincinnati, Ohio

Cincinnati Childrens Hospital Medical Center /ID# 244689, Cincinnati, Ohio

Headache Center of Hope /ID# 242645, Cincinnati, Ohio

Centricity Research Columbus /ID# 231181, Columbus, Ohio

CincyScience /ID# 230046, West Chester, Ohio

IPS Research Company /ID# 227961, Oklahoma City, Oklahoma

Providence Brain and Spine Institute /ID# 231607, Portland, Oregon

Children's Hospital of Philadelphia - Main /ID# 232487, Philadelphia, Pennsylvania

Frontier Clinical Research, LLC - Scottdale /ID# 231913, Scottdale, Pennsylvania

Frontier Clinical Research - Smithfield /ID# 231912, Smithfield, Pennsylvania

Coastal Pediatric Research /ID# 238616, Charleston, South Carolina

Tribe Clinical Research LLC /ID# 230422, Greenville, South Carolina

Duplicate_Premier Neurology, P.C. /ID# 227999, Greer, South Carolina

Access Clinical Trials, Inc. /ID# 228002, Nashville, Tennessee

UT Health Austin at Dell Children's Neurology Clinic /ID# 244266, Austin, Texas

BioBehavioral Research of Austin /ID# 230529, Austin, Texas

Velocity Clinical Research, Austin /ID# 230557, Austin, Texas

Tekton Research - Beaumont /ID# 231207, Beaumont, Texas

Relaro Medical Trials /ID# 239642, Dallas, Texas

Cedar Health Research /ID# 228003, Dallas, Texas

3A Research - East El Paso /ID# 239193, El Paso, Texas

Earle Research /ID# 231548, Friendswood, Texas

DM Clinical Research /ID# 229826, Houston, Texas

Houston Clinical Research Associates /ID# 244889, Houston, Texas

Sante Clinical Research /ID# 246503, Kerrville, Texas

FMC Science /ID# 231915, Lampasas, Texas

Livingspring Family Medical Center /ID# 249869, Mansfield, Texas

AIM Trials /ID# 230142, Plano, Texas

Road Runner Research /ID# 230527, San Antonio, Texas

Family Psychiatry of The Woodlands /ID# 230163, The Woodlands, Texas

ClinPoint Trials /ID# 230295, Waxahachie, Texas

Pantheon Clinical Research /ID# 250703, Bountiful, Utah

Highland Clinical Research /ID# 239362, Salt Lake City, Utah

University of Utah Health Hospital /ID# 230908, Salt Lake City, Utah

Neuropsychiatric Associates LLC/DBA Woodstock Research Center /ID# 238976, Woodstock, Vermont

Office of Maria Ona /ID# 234232, Franklin, Virginia

Children's Hospital of The King's Daughters - Children's Medical Tower /ID# 230581, Norfolk, Virginia

National Clinical Research /ID# 231320, Richmond, Virginia

Core Clinical Research /ID# 227904, Everett, Washington

Frontier Clinical Research - Kingwood /ID# 231914, Kingwood, West Virginia

Mind+ Neurology /ID# 275529, Mequon, Wisconsin

Clinical Research Investigator Group, LLC /ID# 267454, Bayamon, Not set

Puerto Rico Health Institute /ID# 249162, Dorado, Not set

GCM Medical Group PSC /ID# 249643, San Juan, Not set

Caribbean Medical Research Center /ID# 265301, San Juan, Not set

Conditions: Migraine

Learn More ›

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

NCT05304585

Recruiting

Rhabdomyosarcoma is a type of cancer that occurs in the soft tissues in the body. This phase III trial aims to maintain excellent outcomes in patients with very low risk rhabdomyosarcoma (VLR-RMS) while decreasing the burden of therapy using treatment with 24 weeks of vincristine and dactinomycin (VA) and examines the use of centralized molecular risk stratification in the treatment of rhabdomyosarcoma. Another aim of the study it to find out how well patients with low risk rhabdomyosarcoma (LR-... Read More

Gender:

ALL

Ages:

21 years and below

Trial Updated:

06/09/2025

Locations: Children's Hospital of Alabama, Birmingham, Alabama +170 locations

Children's Hospital of Alabama, Birmingham, Alabama

USA Health Strada Patient Care Center, Mobile, Alabama

Phoenix Childrens Hospital, Phoenix, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

Kaiser Permanente Downey Medical Center, Downey, California

Loma Linda University Medical Center, Loma Linda, California

Miller Children's and Women's Hospital Long Beach, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Cedars Sinai Medical Center, Los Angeles, California

Mattel Children's Hospital UCLA, Los Angeles, California

Valley Children's Hospital, Madera, California

UCSF Benioff Children's Hospital Oakland, Oakland, California

Kaiser Permanente-Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

Lucile Packard Children's Hospital Stanford University, Palo Alto, California

Rady Children's Hospital - San Diego, San Diego, California

Naval Medical Center -San Diego, San Diego, California

UCSF Medical Center-Mission Bay, San Francisco, California

Children's Hospital Colorado, Aurora, Colorado

Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center, Denver, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Yale University, New Haven, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

Children's National Medical Center, Washington, District of Columbia

Broward Health Medical Center, Fort Lauderdale, Florida

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

University of Florida Health Science Center - Gainesville, Gainesville, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Nicklaus Children's Hospital, Miami, Florida

AdventHealth Orlando, Orlando, Florida

Arnold Palmer Hospital for Children, Orlando, Florida

Nemours Children's Hospital, Orlando, Florida

Sacred Heart Hospital, Pensacola, Florida

Johns Hopkins All Children's Hospital, Saint Petersburg, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

Saint Mary's Medical Center, West Palm Beach, Florida

Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia

Memorial Health University Medical Center, Savannah, Georgia

Kapiolani Medical Center for Women and Children, Honolulu, Hawaii

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Lurie Children's Hospital-Chicago, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Loyola University Medical Center, Maywood, Illinois

Advocate Children's Hospital-Oak Lawn, Oak Lawn, Illinois

Advocate Children's Hospital-Park Ridge, Park Ridge, Illinois

Saint Jude Midwest Affiliate, Peoria, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Northwestern Medicine Central DuPage Hospital, Winfield, Illinois

Riley Hospital for Children, Indianapolis, Indiana

Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

Wesley Medical Center, Wichita, Kansas

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Norton Children's Hospital, Louisville, Kentucky

Ochsner Medical Center Jefferson, New Orleans, Louisiana

Maine Children's Cancer Program, Scarborough, Maine

University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland

Sinai Hospital of Baltimore, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Massachusetts General Hospital Cancer Center, Boston, Massachusetts

Dana-Farber Cancer Institute, Boston, Massachusetts

UMass Memorial Medical Center - University Campus, Worcester, Massachusetts

C S Mott Children's Hospital, Ann Arbor, Michigan

Children's Hospital of Michigan, Detroit, Michigan

Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

Corewell Health Children's, Royal Oak, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

Children's Mercy Hospitals and Clinics, Kansas City, Missouri

Cardinal Glennon Children's Medical Center, Saint Louis, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Children's Hospital and Medical Center of Omaha, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada

Summerlin Hospital Medical Center, Las Vegas, Nevada

Renown Regional Medical Center, Reno, Nevada

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire

Hackensack University Medical Center, Hackensack, New Jersey

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Albany Medical Center, Albany, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

Roswell Park Cancer Institute, Buffalo, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

Mount Sinai Hospital, New York, New York

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

University of Rochester, Rochester, New York

State University of New York Upstate Medical University, Syracuse, New York

New York Medical College, Valhalla, New York

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Novant Health Presbyterian Medical Center, Charlotte, North Carolina

Duke University Medical Center, Durham, North Carolina

East Carolina University, Greenville, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Broadway Medical Center, Fargo, North Dakota

Children's Hospital Medical Center of Akron, Akron, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Oregon Health and Science University, Portland, Oregon

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania

Geisinger Medical Center, Danville, Pennsylvania

Penn State Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Prisma Health Richland Hospital, Columbia, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

East Tennessee Childrens Hospital, Knoxville, Tennessee

Saint Jude Children's Research Hospital, Memphis, Tennessee

The Children's Hospital at TriStar Centennial, Nashville, Tennessee

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Dell Children's Medical Center of Central Texas, Austin, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

El Paso Children's Hospital, El Paso, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

M D Anderson Cancer Center, Houston, Texas

Covenant Children's Hospital, Lubbock, Texas

UMC Cancer Center / UMC Health System, Lubbock, Texas

Children's Hospital of San Antonio, San Antonio, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Scott and White Memorial Hospital, Temple, Texas

Primary Children's Hospital, Salt Lake City, Utah

University of Virginia Cancer Center, Charlottesville, Virginia

Inova Fairfax Hospital, Falls Church, Virginia

Children's Hospital of The King's Daughters, Norfolk, Virginia

Carilion Children's, Roanoke, Virginia

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

Madigan Army Medical Center, Tacoma, Washington

West Virginia University Charleston Division, Charleston, West Virginia

University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Children's Hospital of Wisconsin, Milwaukee, Wisconsin

Sydney Children's Hospital, Randwick, New South Wales

The Children's Hospital at Westmead, Westmead, New South Wales

Perth Children's Hospital, Perth, Western Australia

Alberta Children's Hospital, Calgary, Alberta

University of Alberta Hospital, Edmonton, Alberta

British Columbia Children's Hospital, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

IWK Health Centre, Halifax, Nova Scotia

Hospital for Sick Children, Toronto, Ontario

The Montreal Children's Hospital of the MUHC, Montreal, Quebec

Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec

Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke, Quebec

CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Quebec, Not set

Starship Children's Hospital, Grafton, Auckland

Christchurch Hospital, Christchurch, Not set

Conditions: Embryonal Rhabdomyosarcoma, Fusion-Negative Alveolar Rhabdomyosarcoma, Spindle Cell/Sclerosing Rhabdomyosarcoma

Learn More ›

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

NCT05382338

Recruiting

This phase III trial tests two hypotheses in patients with low-risk and average-risk medulloblastoma. Medulloblastoma is a type of cancer that occurs in the back of the brain. The term, risk, refers to the chance of the cancer coming back after treatment. Subjects with low-risk medulloblastoma typically have a lower chance of the cancer coming back than subjects with average-risk medulloblastoma. Although treatment for newly diagnosed average-risk and low-risk medulloblastoma is generally effective at treating the cancer, there are still concerns about the side effects of such treatment. Side effects or unintended health conditions that arise due to treatment include learning difficulties, hearing loss or other issues in performing daily activities. Standard therapy for newly diagnosed average-risk or low-risk medulloblastoma includes surgery, radiation therapy, and chemotherapy (including cisplatin). Cisplatin may cause hearing loss as a side effect. In the average-risk medulloblastoma patients, this trial tests whether the addition of sodium thiosulfate (STS) to standard of care chemotherapy and radiation therapy reduces hearing loss. Previous studies with STS have shown that it may help reduce or prevent hearing loss caused by cisplatin. In the low-risk medulloblastoma patients, the study tests whether a less intense therapy (reduced radiation) can provide the same benefits as the more intense therapy. The less intense therapy may cause fewer side effects. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Cisplatin is in a class of medications known as platinum-containing compounds. It works by killing, stopping or slowing the growth of cancer cells. The overall goals of this study are to see if giving STS along with standard treatment (radiation therapy and chemotherapy) will reduce hearing loss in medulloblastoma patients and to compare the overall outcome of patients with medulloblastoma treated with STS to patients treated without STS on a previous study in order to make sure that survival and recurrence of tumor is not worsened. Read Less

Gender:

ALL

Ages:

Between 4 years and 21 years

Trial Updated:

06/09/2025

Locations: Children's Hospital of Alabama, Birmingham, Alabama +77 locations

Children's Hospital of Alabama, Birmingham, Alabama

USA Health Strada Patient Care Center, Mobile, Alabama

Phoenix Childrens Hospital, Phoenix, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

Loma Linda University Medical Center, Loma Linda, California

Miller Children's and Women's Hospital Long Beach, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Valley Children's Hospital, Madera, California

Kaiser Permanente-Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

Rady Children's Hospital - San Diego, San Diego, California

UCSF Medical Center-Mission Bay, San Francisco, California

Children's Hospital Colorado, Aurora, Colorado

Alfred I duPont Hospital for Children, Wilmington, Delaware

Children's National Medical Center, Washington, District of Columbia

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

Nicklaus Children's Hospital, Miami, Florida

Arnold Palmer Hospital for Children, Orlando, Florida

Nemours Children's Hospital, Orlando, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

University of Illinois, Chicago, Illinois

Riley Hospital for Children, Indianapolis, Indiana

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

Norton Children's Hospital, Louisville, Kentucky

Children's Hospital New Orleans, New Orleans, Louisiana

Sinai Hospital of Baltimore, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

C S Mott Children's Hospital, Ann Arbor, Michigan

Children's Hospital of Michigan, Detroit, Michigan

Corewell Health Children's, Royal Oak, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

Children's Mercy Hospitals and Clinics, Kansas City, Missouri

Cardinal Glennon Children's Medical Center, Saint Louis, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Saint Peter's University Hospital, New Brunswick, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

Albany Medical Center, Albany, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

Roswell Park Cancer Institute, Buffalo, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

Stony Brook University Medical Center, Stony Brook, New York

State University of New York Upstate Medical University, Syracuse, New York

New York Medical College, Valhalla, New York

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Broadway Medical Center, Fargo, North Dakota

Children's Hospital Medical Center of Akron, Akron, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Legacy Emanuel Children's Hospital, Portland, Oregon

Oregon Health and Science University, Portland, Oregon

Geisinger Medical Center, Danville, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Prisma Health Richland Hospital, Columbia, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Dell Children's Medical Center of Central Texas, Austin, Texas

Medical City Dallas Hospital, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

El Paso Children's Hospital, El Paso, Texas

Children's Hospital of San Antonio, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

University of Virginia Cancer Center, Charlottesville, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Children's Hospital of Wisconsin, Milwaukee, Wisconsin

Conditions: Childhood Medulloblastoma

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Improving Exercise Capacity With a Tailored Physical Activity Intervention

NCT05595577

Recruiting

The purpose of this research is to test whether participating in either a physical activity intervention or a series of educational classes will help to preserve exercise capability, heart function, brain-based activities (like memory), and quality of life. Participants will be randomized to 1 of 2 pathways: * First pathway consists of organized health workshops. These workshops are intended to provide information on topics such as proper nutrition, management of stress, sleep practices, and e... Read More

Gender:

ALL

Ages:

Between 18 years and 85 years

Trial Updated:

06/09/2025

Locations: Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina +1 locations

Conditions: Non Hodgkin Lymphoma, Heart; Functional Disturbance, Hodgkin Lymphoma, Quality of Life, Stage I Breast Cancer, Stage II Breast Cancer, Stage III Breast Cancer

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Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)

NCT05743244

Recruiting

A multi-center, placebo-controlled, double blind, 1:1:1 randomized control clinical trial testing two different JAK Inhibitors abrocitnib, ritlecitinib, and placebo in subjects with recent onset Stage 3 Type 1 Diabetes within 100 days of diagnosis.

Gender:

ALL

Ages:

Between 12 years and 35 years

Trial Updated:

06/09/2025

Locations: Children's Hospital Orange County, Orange, California +26 locations

Children's Hospital Orange County, Orange, California

Stanford University, Palo Alto, California

University of California- San Francisco, San Francisco, California

Barbara Davis Center at University of Colorado Anschutz Medical Campus, Aurora, Colorado

Yale University School of Medicine, New Haven, Connecticut

University of Florida, Gainesville, Florida

University of Miami, Miami, Florida

University of South Florida Diabetes Center, Tampa, Florida

Emory Children's Center, Atlanta, Georgia

University of Chicago, Chicago, Illinois

Indiana University, Indianapolis, Indiana

Joslin Diabetes Center, Boston, Massachusetts

University of Minnesota, Minneapolis, Minnesota

The Children's Mercy Hospital, Kansas, Missouri

UBMD Pediatrics, Buffalo, New York

Columbia University-Naomi Berrie Diabetes Center, New York, New York

Joslin Center at SUNY Upsate, Syracuse, New York

University of Pittsburgh, Pittsburgh, Pennsylvania

Vanderbilt University Medical Center, Nashville, Tennessee

University of Texas Southwestern, Dallas, Texas

University of Utah, Salt Lake City, Utah

Benaroya Research Institute, Seattle, Washington

Queensland Children's Hospital, South Brisbane, Queensland

Women and Children's Hospital-Adelaide, Adelaide, South Australia

3. Royal Melbourne Hospital, Parkville, Victoria

Perth Children's Hospital, Nedlands, West Australia

Hospital for Sick Children, Toronto, Ontario

Conditions: Diabetes Mellitus, Type 1

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A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adults With Diabetic Gastroparesis

NCT05832151

Recruiting

The goal of this clinical trial is to evaluate if the study drug CIN-102 (deudomperidone) can help reduce the symptoms associated with diabetic gastroparesis in adult patients. The main questions it aims to answer are: * To evaluate the efficacy of CIN-102 on symptoms of gastroparesis when given to patients with diabetic gastroparesis compared to a placebo * To evaluate the safety and tolerability of CIN-102 when given to patients with diabetic gastroparesis compared to a placebo Participants... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/09/2025

Locations: Digestive Health Specialists of the Southeast, Dothan, Alabama +99 locations

Digestive Health Specialists of the Southeast, Dothan, Alabama

G & L Research, LLC, Foley, Alabama

Clinical Research Associates, LLC, Huntsville, Alabama

Phoenix Medical Research Institute, LLC, Peoria, Arizona

Onyx Clinical Research, Phoenix, Arizona

Del Sol Research Management, LLC, Tucson, Arizona

Preferred Research Partners, Inc., Little Rock, Arkansas

Applied Research Center of Arkansas, Little Rock, Arkansas

Arkansas Gastroenterology - North Little Rock, North Little Rock, Arkansas

Alliance Research Institute - Bell Gardens, Bell Gardens, California

Hope Clinical Research LLC, Canoga Park, California

Alliance Research Institute, LLC, Canoga Park, California

Erick H. Alayo Medical Corporation, Chula Vista, California

GW Research Inc., Chula Vista, California

Kindred Medical Institute for Clinical Trials, LLC, Corona, California

New Hope Research Development, Corona, California

Aurora Care Clinic, Costa Mesa, California

Paragon Rx Clinical, Garden Grove, California

Valley View Wellness and Medical Center - VVCRD, Garden Grove, California

Torrance Clinical Research Institute Inc., Lomita, California

Angel City Research, Los Angeles, California

Facey Medical Research, Mission Hills, California

Millennium Clinical Trials, Thousand Oaks, California

Innovative Research of West Florida, Clearwater, Florida

USA and International Research Inc., Doral, Florida

Advanced Medical Research Group, Hollywood, Florida

Nature Coast Clinical Research, Inverness, Florida

ClinCloud LLC, Maitland, Florida

A+ Research Inc, Miami, Florida

International Research Associates LLC - Breton, Miami, Florida

Advanced Research Institute Inc, New Port Richey, Florida

Gastroenterology of Greater Orlando, Orange City, Florida

Tandem Clinical Research - Viera, Viera, Florida

Summit Clinical Research, LLC, Athens, Georgia

Atlanta Center for Gastroenterology P.C., Decatur, Georgia

Medisphere Medical Research Center, Evansville, Indiana

Lutheran Medical Group, Fort Wayne, Indiana

University of Kansas Medical Center (KUMC), Kansas City, Kansas

DelRicht Clinical Research - Overland Park, Overland Park, Kansas

Kansas Medical Clinic, P.A., Topeka, Kansas

Alliance for Multispecialty Research - Wichita West, Wichita, Kansas

University of Louisville, Louisville, Kentucky

DelRicht Clinical Research - Louisville, Louisville, Kentucky

Delta Research Partners, Bastrop, Louisiana

Tandem Clinical Research GI - Houma, Houma, Louisiana

Tandem Clinical Research, Marrero, Louisiana

Tandem Clinical Research GI - Metairie, Metairie, Louisiana

Clinical Research Institute of Michigan, LLC, Chesterfield, Michigan

Aa Mrc, Llc, Flint, Michigan

Clinical Research Institute of Michigan, LLC - Troy, Troy, Michigan

Gastroenterology Associates of Western Michigan, Wyoming, Michigan

Kansas City Research Institute, Kansas City, Missouri

Washington University School of Medicine, Saint Louis, Missouri

St. Charles Clinical Research, Weldon Spring, Missouri

Montana Medical Research, Inc., Missoula, Montana

American Institute of Medical Research, Las Vegas, Nevada

Digestive Disease Specialists, Las Vegas, Nevada

Allied Health Clinical Research Organization, LLC (AHCRO) - Englewood, Englewood, New Jersey

Allied Health Clinical Research Organization, LLC (AHCRO) - Freehold, Freehold, New Jersey

Allied Health Clinical Research Organization, LLC (AHCRO) - Jackson, Jackson, New Jersey

NY Scientific, Brooklyn, New York

Smart Medical Research, Brooklyn, New York

Velocity Clinical Research - Syracuse, East Syracuse, New York

Tandem Clinical Research GI- New York, New York, New York

A1 Clinical Network, Richmond Hill, New York

OnSite Clinical Solutions, LLC, Charlotte, North Carolina

Atrium Health - Center for Digestive Health, Charlotte, North Carolina

Research Carolina Elite, LLC, Denver, North Carolina

Coastal Research Institute, LLC, Fayetteville, North Carolina

Cross Creek Medical, PA, Fayetteville, North Carolina

Triad Clinical Trials LLC, Greensboro, North Carolina

Peters Medical Research, High Point, North Carolina

Carolina's GI Research, Raleigh, North Carolina

Cleveland Clinic, Cleveland, Ohio

Remington Davis, Inc., Columbus, Ohio

DelRicht Clinical Research - Cincinnati, Mason, Ohio

Northshore Gastroenterology Research, LLC, Westlake, Ohio

Options Health Research, Tulsa, Oklahoma

Velocity Clinical Research, Medford, Oregon

Susquehanna Research Group, LLC, Harrisburg, Pennsylvania

Galen Medical Group - Downtown Gastroenterology Location, Chattanooga, Tennessee

WR ClinSearch, Chattanooga, Tennessee

DelRicht Clinical Research - Nashville, Henderson, Tennessee

North Hills Medical Research Inc. (North Hills Familiy Medicine), Arlington, Texas

Zenos Clinical Research, Dallas, Texas

Texas Gastro Research, LLC, El Paso, Texas

Houston Methodist Research Institute, Houston, Texas

Amir A Hassan, MD, PA, Houston, Texas

Care and Cure Clinic, Houston, Texas

Pioneer Research Solutions Inc., Houston, Texas

Epic Clinical Research, Lewisville, Texas

Texas Tech University Health Sciences Center, Lubbock, Texas

Biopharma Informatic, LLC, McAllen, Texas

DelRicht Clinical Research - McKinney, McKinney, Texas

Gastroenterology Research of San Antonio, San Antonio, Texas

A1 Clinical Network, Spring, Texas

HP Clinical Research (Val R. Hansen), Bountiful, Utah

Velocity Clinical Research - Salt Lake City, West Jordan, Utah

Manassas Clinical Research Center, Manassas, Virginia

Wisconsin Center for Advanced Research, Milwaukee, Wisconsin

Conditions: Diabetic Gastroparesis

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