Impact of a Health Technology Intervention on Patient Activation in Multiple Myeloma
NCT05673083
Recruiting
The goal of this pilot study is to evaluate the impact of All4Cure enrollment on patients with multiple myeloma. The main question it aims to answer are: • Does All4Cure effect patient activation as assessed by the PAM-13 survey? Participants will be asked to: * fill out quarterly PAM-13 surveys through the All4Cure website to assess patient activation. * fill out monthly Patient Reported Outcome (PRO) surveys through the All4Cure website. * fill out a baseline and exit All4Cure surveys throu... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Highlands Oncology Group, Fayetteville, Arkansas +6 locations
Conditions: Multiple Myeloma in Relapse, Multiple Myeloma, Multiple Myeloma, Refractory, Multiple Myeloma With Failed Remission
Register for Updates
Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells
NCT05705024
Recruiting
The proposed Conventional Cohort Expansion Study involves the use of Mesenchymal Stromal Cells (MSCs) are derived from the bone marrow. We previously studied the safety of subconjunctival injection of allogeneic bone marrow-derived MSCs in patients with nonhealing epitheliopathy (IRB Protocol 2020-0334). In the present study, we want to study the efficacy of this treatment on chronic epitheliopathies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Department of Ophthalmology and Visual Sciences, Chicago, Illinois +3 locations
Conditions: Corneal Ulcer
Register for Updates
A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
NCT05824975
Recruiting
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and therapeutic activity of GI-102 as a single agent and in combination with conventional anti-cancer drugs, pembrolizumab or trastuzumab deruxtecan(T-DXd) over a range of advanced and/or metastatic solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Mayo Clinic in Arizona, Scottsdale, Arizona +10 locations
Conditions: Advanced Solid Tumor, Metastatic Solid Tumor, Soft Tissue Sarcoma (STS), Platinum-resistant Ovarian Cancer (PROC), Hepatocellular Carcinoma (HCC), Colorectal Cancer (CRC), HER2 Negative Breast Cancer, Cutaneous Melanoma, Renal Cell Carcinoma (RCC)
Register for Updates
Reducing AIR Pollution Exposure to Lower Blood PRESSURE Among New York City Public Housing Residents
NCT05874479
Recruiting
Fine particulate matter \<2.5 µm (PM2.5) air pollution is the fifth leading risk factor for global mortality, with the largest portion of deaths due to cardiovascular disease (CVD). While several mechanisms are responsible, PM2.5-induced elevations in blood pressure (BP) may be relevant. Indoor portable air cleaners (PACs) are a novel approach to reduce exposure to PM2.5 and potentially lower blood pressure. The current study is being conducted to provide evidence that PACs reduce PM2.5 exposure... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
11/21/2024
Locations: NYU Langone Health, New York, New York
Conditions: Blood Pressure
Register for Updates
ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation Vs Control in Redo Ablation Patients
NCT05988411
Recruiting
This is a Prospective, controlled, single-blind, randomized (2:1, Intervention:Control) clinical trial. The purpose of the study is to determine the role of adjunctive renal sympathetic denervation in the prevention of Atrial Fibrillation (AF) recurrence in patients with hypertension scheduled for a redo AF ablation procedure for paroxysmal or persistent AF. Patients will be randomized to either i) AF ablation (Control) or ii) AF ablation + renal sympathetic denervation (Intervention).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Arrhythmia Research Group, Jonesboro, Arkansas +7 locations
Conditions: Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Register for Updates
Empowered Relief for Youth
NCT05998369
Recruiting
The purpose of this pilot study is to examine the feasibility and preliminary efficacy of Empowered Relief for Youth with chronic pain (ER-Y). ER-Y is a single-session pain management class for youth focused on pain science education and teaching self-regulatory skills for pain management based on the evidence-based adult ER class. Feasibility and acceptability of ER-Y will be assessed post-class. Preliminary efficacy will be assessed by administering surveys at baseline, 4-weeks, 8-weeks, and 1... Read More
Gender:
ALL
Ages:
Between 10 years and 18 years
Trial Updated:
11/21/2024
Locations: Stanford University, Palo Alto, California
Conditions: Chronic Pain, Musculoskeletal Pain, Fibromyalgia, Neuropathic Pain, Complex Regional Pain Syndromes, Abdominal Pain
Register for Updates
Dance Program for Youth With Cerebral Palsy
NCT06100562
Recruiting
The goal of this prospective cohort study is to learn about the impact of an adapted dance program in youth with cerebral palsy. The main questions it aims to answer are: 1. Are there clinically significant benefits for children with cerebral palsy who participate in an Adaptive Dance Program? 2. Is it feasible to implement an adaptive dance program using action-observation principles for children diagnosed with Cerebral Palsy (CP)? Participants will complete a pre-dance program assessment, par... Read More
Gender:
ALL
Ages:
Between 4 years and 17 years
Trial Updated:
11/21/2024
Locations: Scottish Rite for Children, Frisco, Texas
Conditions: Cerebral Palsy
Register for Updates
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
NCT06112093
Recruiting
This study aims to examine the long-term effect of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, on chronic headaches following mild traumatic brain injury (mTBI). rTMS has been shown to be effective in reducing chronic headaches without side effects commonly seen in medications, such as sleepiness and addiction. This study uses rTMS to manage chronic headaches to improve post-concussion symptoms and reduce the economic burden due to delayed rec... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
11/21/2024
Locations: SUNY Upstate Medical University, Syracuse, New York
Conditions: Brain Concussion, Mild Traumatic Brain Injury, Headache, Post-Concussion Symptoms
Register for Updates
Characterization and Clinical Trial of a Variable Friction Shoe
NCT06234124
Recruiting
More than one million Americans present with foot drop after stroke. As the aging population grows in the United States and across the world, incidence of stroke will grow as age is a key risk factor, thus there will be a need for low-cost, easy-to-use, and scalable solutions to administer proper therapy to promote recovery. This study will evaluate a Variable Friction shoe (VF shoe), a new low-cost medical device, for foot drop in an at-home setting.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Stroke
Register for Updates
Sequencing Antibody Drug Conjugates in ER+/HER2 LOW MBC
NCT06263543
Recruiting
The purpose of this research study is to see if the medication sacituzumab govitecan (SG) is effective at the currently approved dose and schedule in people who have previously received trastuzumab deruxtecan (T-DXd) for the treatment of metastatic, hormone receptor positive (HR+)/human epidermal growth factor 2 low (HER2 low) breast cancer. Although SG is approved to treat metastatic HR+/HER2 negative breast cancer, the aim of this study is to determine if SG is still effective specifically in... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: UCLA Jonsson Comprehensive Cancer Center, Los Angeles, California +2 locations
Conditions: Breast Cancer, Metastatic Breast Cancer, Advanced Breast Cancer, Hormone-receptor-positive Breast Cancer, Human Epidermal Growth Factor 2 Low Breast Cancer
Register for Updates
Mobile Application to Improve Health-Related Outcomes in Patients With Advanced Lung Cancer
NCT06427954
Recruiting
Multi-site randomized trial of the THRIVE digital health application versus usual care to evaluate the effect of THRIVE on quality of life (QOL), physical and psychological symptoms, coping, and self-efficacy in 250 patients with newly diagnosed advanced lung cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: University of California Los Angeles, Los Angeles, California +2 locations
Conditions: Lung Cancer
Register for Updates
Remote Trial - Tobacco Product Standard (VLNC)
NCT06442384
Recruiting
The goal of this pilot project is to explore the feasibility of a real-world marketplace study design examining the effects of a reduced nicotine product standard for cigarettes on smoking in the context of a flavor restriction vs. no restriction on e-cigarettes in smokers switched to very low nicotine content cigarettes.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
11/21/2024
Locations: Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Tobacco Use
Register for Updates