All Clinical Trials

A listing of 23118 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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Paid Clinical Studies Nationwide

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Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

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Healthy Volunteer Study

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Recruiting

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Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

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A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130850 in Participants With Advanced Solid and Hematologic Tumors

NCT06188208

Recruiting

A FIH study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of VVD-130850, as single agent and in combination with checkpoint inhibition, in participants with advanced solid and hematologic tumors.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: California Research Institute, Los Angeles, California +19 locations

Conditions: Advanced Solid Tumors, Advanced Hematologic Tumors

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A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

NCT06468228

Recruiting

Hidradenitis suppurativa (HS) is a chronic and often painful inflammatory skin disease which includes the forming of lumps, abscesses and scars in areas of the skin such as under the breasts, under armpits, inner thighs, groin and buttocks. This study will compare lutikizumab versus placebo for the treatment of adult and adolescent participants with the signs and symptoms of moderate to severe HS . Lutikizumab is an investigational drug being developed for the treatment of HS. During Period 1 of the study, participants will placed in 1 of 2 groups called treatment arms. There is a 1 in 2 chance that participants will be assigned to placebo. Around 1280 adult and adolescent participants with moderate to severe HS will be enrolled in the study at approximately 275 sites world wide. During Period 2, participants that were part of the lutikizumab treatment arm in Period 1 will be re-randomized to 1 of 2 lutikizumab treatment arms. Participants that were part of the Placebo arm in Period 1 will start Period 2 with an initiation of lutikizumab followed by a re-randomization to 1 of 2 lutikizumab treatment arms. In Period 1, participants will receive subcutaneous injections of lutikizumab or placebo every week for 16 weeks. In Period 2, participants that were randomized to lutikizumab in Period 1 will receive subcutaneous injections of lutikizumab every week or every other week for 36-weeks. Participants that were randomized to the placebo arm in Period 1 will receive subcutaneous injections of lutikizumab every week for 16 weeks, then either every week or every other week for 20 weeks. Period 3 is the Long Term Extentsion (LTE) and through Week 68, participants will continue to receive lutikizumab SC using the same assigned dosing regimen from the end of Period 2 for 16 weeks followed by open-label lutikizumab EOW for 140 weeks. Participants in the US that complete Periods 1 \& 2 will have the option to enroll in a 156-week open-label Sub-Study that will assess the long term safety and efficacy of lutikizumab in a prefilled pen. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires and diaries. Read Less

Gender:

ALL

Ages:

12 years and above

Trial Updated:

06/17/2025

Locations: Cahaba Dermatology & Skin Health Center /ID# 263795, Birmingham, Alabama +232 locations

Cahaba Dermatology & Skin Health Center /ID# 263795, Birmingham, Alabama

Medical Dermatology Specialists /ID# 263394, Phoenix, Arizona

Dermatology Trial Associates /ID# 264587, Bryant, Arkansas

Arkansas Research Trials /ID# 263901, North Little Rock, Arkansas

Private Practice - Dr. Tooraj Raoof /ID# 263756, Encino, California

Dermatology Research Associates - Los Angeles /ID# 263765, Los Angeles, California

Stanford University School of Medicine - Redwood City /ID# 263711, Redwood City, California

Integrative Skin Science and Research /ID# 264600, Sacramento, California

Clinical Trials Research Institute /ID# 263743, Thousand Oaks, California

Clearlyderm Dermatology - West Boca /ID# 265023, Boca Raton, Florida

Apex Clinical Trials /ID# 263815, Brandon, Florida

TrueBlue Clinical Research /ID# 265041, Brandon, Florida

Skin Care Research - Hollywood /ID# 263805, Hollywood, Florida

GSI Clinical Research, LLC /ID# 263827, Margate, Florida

Sullivan Dermatology /ID# 263511, Miami, Florida

Renstar Medical Research - Ocala - Northeast 1st Avenue /ID# 263842, Ocala, Florida

Skin Care Research - Tampa /ID# 263819, Tampa, Florida

Advanced Clinical Research Institute /ID# 263808, Tampa, Florida

University of South Florida /ID# 269624, Tampa, Florida

Alliance Clinical Research of Tampa /ID# 264594, Tampa, Florida

Centricity Research Columbus Dermatology /ID# 266530, Columbus, Georgia

Cleaver Medical Group Dermatology /ID# 263845, Dawsonville, Georgia

Treasure Valley Medical Research /ID# 263671, Boise, Idaho

Northwestern University Feinberg School of Medicine /ID# 265007, Chicago, Illinois

Arlington Dermatology /ID# 263410, Rolling Meadows, Illinois

Dawes Fretzin, LLC /ID# 264601, Indianapolis, Indiana

Dermatology Partners of Leawood /ID# 263533, Leawood, Kansas

Equity Medical, LLC /ID# 268590, Bowling Green, Kentucky

Dermatology Specialists Research (DS Research) - Kentucky /ID# 263343, Louisville, Kentucky

Tulane University School of Medicine /ID# 263899, New Orleans, Louisiana

Beth Israel Deaconess Medical Center /ID# 263709, Boston, Massachusetts

Hamzavi Dermatology - Canton /ID# 263538, Canton, Michigan

Michigan Center for Medical Research /ID# 263547, Clarkston, Michigan

Dermatology and Skin Center of Lees Summit /ID# 263567, Lee's Summit, Missouri

MediSearch Clinical Trials /ID# 263582, Saint Joseph, Missouri

Vivida Dermatology- Flamingo /ID# 263716, Las Vegas, Nevada

Dartmouth Hitchcock Medical Center - Old Etna Road /ID# 263713, Lebanon, New Hampshire

ActivMed Practice and Research, LLC /ID# 263387, Portsmouth, New Hampshire

Mount Sinai Doctors - Dermatology /ID# 264602, New York, New York

Atrium Health Wake Forest Baptist Medical Center /ID# 264507, Winston-Salem, North Carolina

Dermatology of Greater Columbus /ID# 263497, Bexley, Ohio

University Hospitals Cleveland Medical Center /ID# 263600, Cleveland, Ohio

Ohio State Officenter Gahanna /ID# 263598, Gahanna, Ohio

Dermatologists of Southwest Ohio - Mason /ID# 263588, Mason, Ohio

Apex Clinical Research Center /ID# 272787, Mayfield Heights, Ohio

Dermatology Partners /ID# 264999, Philadelphia, Pennsylvania

University of Pittsburgh Medical Center /ID# 264590, Pittsburgh, Pennsylvania

Clinical Research Center of the Carolinas /ID# 263407, Charleston, South Carolina

Medical University of South Carolina /ID# 263890, Charleston, South Carolina

ADCS - Spartanburg /ID# 267207, Spartanburg, South Carolina

Arlington Research Center, Inc /ID# 263895, Arlington, Texas

Bellaire Dermatology Associates /ID# 263850, Bellaire, Texas

Studies in Dermatology LLC /ID# 263399, Cypress, Texas

Reveal Research Institute, Dallas /ID# 267233, Dallas, Texas

Center for Clinical Studies - Houston - Binz Street /ID# 263378, Houston, Texas

Texas Dermatology Research Center /ID# 264488, Plano, Texas

Texas Dermatology and Laser Specialists /ID# 263778, San Antonio, Texas

Dermatology Associates of Tyler /ID# 265002, Tyler, Texas

University of Utah /ID# 263818, Murray, Utah

Virginia Clinical Research /ID# 264553, Norfolk, Virginia

Dermatology Specialists of Spokane /ID# 264499, Spokane, Washington

Paratus Clinical Research Woden /ID# 263125, Phillip, Australian Capital Territory

Momentum Clinical Research /ID# 263192, Darlinghurst, New South Wales

Premier Dermatology /ID# 263124, Kogarah, New South Wales

Veracity Clinical Research /ID# 263126, Woolloongabba, Queensland

Sinclair Dermatology - Melbourne /ID# 263121, East Melbourne, Victoria

Medizinische Universitaet Graz /ID# 263306, Graz, Steiermark

Medizinische Universitaet Wien /ID# 264043, Wien, Not set

Universite Libre de Bruxelles - Hopital Erasme /ID# 263097, Anderlecht, Bruxelles-Capitale

Cliniques Universitaires UCL Saint-Luc /ID# 263096, Bruxelles, Bruxelles-Capitale

Universitair Ziekenhuis Brussel /ID# 263101, Jette, Bruxelles-Capitale

Grand Hôpital de Charleroi - Les Viviers /ID# 263100, Charleroi, Hainaut

CHU de Liège /ID# 263095, Liège, Liege

UZ Gent /ID# 263099, Gent, Oost-Vlaanderen

Universitair Ziekenhuis Leuven /ID# 263098, Leuven, Vlaams-Brabant

Klinicki centar Banja Luka /ID# 265905, Banja Luka, Republika Srpska

Klinicki centar Banja Luka /ID# 265909, Banja Luka, Republika Srpska

Clinical Center University of Sarajevo - Bolnička /ID# 265908, Sarajevo, Not set

Acibadem City Clinic Tokuda Hospital /ID# 263300, Sofiya, Sofia

ASMC-IPSMC-Skin and Venereal Diseases /ID# 262891, Sofiya, Sofia

Medical Center Hera EOOD /ID# 263010, Sofiya, Sofia

Medical Center Cordis /ID# 262894, Pleven, Not set

Diagnostic consultative center Focus-5 /ID# 262893, Sofiya, Not set

UMHAT Professor Stoyan Kirkovich /ID# 262892, Stara Zagora, Not set

Beacon Dermatology Inc /ID# 264262, Calgary, Alberta

Rejuvenation Dermatology - Edmonton Downtown /ID# 265963, Edmonton, Alberta

Stratica Dermatology /ID# 265856, Edmonton, Alberta

Interior Dermatology Centre - Probity - PPDS /ID# 266202, Kelowna, British Columbia

Brunswick Dermatology Center /ID# 264260, Fredericton, New Brunswick

Karma Clinical Trials /ID# 265962, St. John's, Newfoundland and Labrador

Skin Health /ID# 267735, Cobourg, Ontario

Leader Research /ID# 266114, Hamilton, Ontario

DermEffects /ID# 265262, London, Ontario

Derm Care Clinic /ID# 265261, Mississauga, Ontario

York Dermatology Clinic & Research Centre /ID# 265265, Richmond Hill, Ontario

FACET Dermatology /ID# 265267, Toronto, Ontario

Private Practice - Dr. Kim Papp Clinical Research /ID# 265266, Waterloo, Ontario

Centre de Recherche Saint-Louis /ID# 265855, Québec, Quebec

Private Practice - Dr. Angelique Gagne-Henley /ID# 264263, St-Jérôme, Quebec

SkinSense Dermatology /ID# 265964, Saskatoon, Saskatchewan

Diex Recherche Quebec Inc. /ID# 265263, Quebec, Not set

Klinicki bolnicki centar Osijek /ID# 265916, Osijek, Osjecko-baranjska Zupanija

Klinicki Bolnicki Centar Zagreb /ID# 263989, Grad Zagreb, Not set

Specialty hospital Medico /ID# 263922, Rijeka, Not set

Fakultní nemocnice Ostrava /ID# 264041, Ostrava, Ostrava-mesto

Karlovarska Krajska Nemocnice - Karlovy Vary /ID# 265354, Karlovy Vary, Not set

Herlev and Gentofte Hospital /ID# 265839, Hellerup, Hovedstaden

Aarhus Universitetshospital - Skejby /ID# 265657, Aarhus, Midtjylland

Hopital Edouard Herriot /ID# 263456, Lyon, Auvergne-Rhone-Alpes

Centre Hospitalier Universitaire de Saint Etienne - Hopital Nord /ID# 263459, St-Priest-en-Jarez, Loire

Cabinet medical - Le bateau Blanc /ID# 263465, Martigues, Provence-Alpes-Cote-d Azur

Centre Hospitalier Universitaire de Rouen (CHU)- Hopital Charles Nicolle /ID# 263995, Rouen, Seine-Maritime

Groupe Hospitalier Paris Saint-Joseph /ID# 263996, Paris, Not set

Polyclinique Courlancy /ID# 263313, Reims, Not set

Universitaetsklinikum Freiburg /ID# 263659, Freiburg, Baden-Wuerttemberg

Universitaetsklinikum Tuebingen /ID# 271718, Tübingen, Baden-Wuerttemberg

Universitaetsklinikum Erlangen /ID# 263075, Erlangen, Bayern

Beldio Research GmbH /ID# 263074, Memmingen, Bayern

Rosenpark Research /ID# 269202, Darmstadt, Hessen

Fachklinik Bad Bentheim /ID# 263067, Bad Bentheim, Niedersachsen

Katholisches Klinikum Bochum /ID# 262976, Bochum, Nordrhein-Westfalen

Universitaetsklinikum Muenster /ID# 263068, Muenster, Nordrhein-Westfalen

Hautarztpraxis Mortazawi /ID# 271673, Remscheid, Nordrhein-Westfalen

Hautarztpraxis Dr. Kirschner /ID# 263656, Mainz, Rheinland-Pfalz

Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 263076, Berlin, Not set

University General Hospital Attikon /ID# 263413, Athens, Attiki

General Hospital Andreas Syggros /ID# 263417, Athens, Attiki

Hospital of Skin and Venereal Diseases- Thessaloniki /ID# 263416, Thessaloniki, Not set

Papageorgiou General Hospital /ID# 263415, Thessaloniki, Not set

Dermos S.A. /ID# 265857, Guatemala City, Not set

Prosalud /Id# 266586, Guatemala, Not set

Debreceni Egyetem-Klinikai Kozpont /ID# 263423, Debrecen, Hajdu-Bihar

Somogy Varmegyei Kaposi Mor Oktato Korhaz /ID# 263424, Kaposvár, Somogy

Semmelweis Egyetem /ID# 263451, Budapest, Not set

Pécsi Tudományegyetem /ID# 264120, Pécs, Not set

Our Lady of Lourdes Hospital - Drogheda /ID# 265893, Drogheda, Louth

South Infirmary Victoria University Hospital /ID# 265872, Cork, Not set

University College Dublin /ID# 265875, Dublin, Not set

Mater Misericordiae University Hospital /ID# 265914, Dublin, Not set

HaEmek Medical Center /ID# 267297, Afula, H_efa

Rambam Health Care Campus /ID# 262994, Haifa, H_efa

Rabin Medical Center /ID# 262992, Petah Tikva, HaMerkaz

Galilee Medical Center /ID# 262995, Naharia, HaTsafon

The Chaim Sheba Medical Center /ID# 262993, Ramat Gan, Tel-Aviv

Tel Aviv Sourasky Medical Center /ID# 266581, Tel Aviv, Tel-Aviv

Hadassah Medical Center-Hebrew University /ID# 262884, Jerusalem, Not set

AZIENDA USL TOSCANA CENTRO - Ospedale Piero Palagi /ID# 263454, Florence, Firenze

IRCCS Istituto Clinico Humanitas /ID# 263503, Rozzano, Lombardia

Azienda Ospedaliera Universitaria Federico II /ID# 263539, Naples, Napoli

Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Università Cattolica /ID# 263473, Rome, Roma

AOU Policlinico G. Rodolico - San Marco /ID# 263469, Catania, Not set

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico /ID# 263471, Milano, Not set

Nagoya City University Hospital /ID# 263874, Nagoya, Aichi

Fujita Health University Hospital /ID# 265440, Toyoake, Aichi

Takagi Dermatological Clinic /ID# 264810, Obihiro-Shi, Hokkaido

Iwate Medical University Uchimaru Medical Center /ID# 273799, Morioka, Iwate

University Hospital Kyoto Prefectural University of Medicine /ID# 264291, Kyoto-shi, Kyoto

University of the Ryukyus Hospital /ID# 264605, Ginowan-shi, Okinawa

Kindai University Hospital /ID# 264322, Osaka sayama-shi, Osaka

Osaka Metropolitan University Hospital /ID# 265682, Osaka-shi, Osaka

Dokkyo Medical University Saitama Medical Center /ID# 265400, Koshigaya, Saitama

Fukuoka University Hospital /ID# 263991, Fukuoka, Not set

Nihon University Itabashi Hospital /ID# 264661, Tokyo, Not set

Pusan National University Hospital /ID# 271496, Busan, Busan Gwang Yeogsi

SoonChunHyang University Hospital Cheonan /ID# 271320, Cheonan-si, Chungcheongnamdo

Korea University Ansan Hospital /ID# 264227, Ansan-si, Gyeonggido

CHA Bundang Medical Center /ID# 264225, Seongnam, Gyeonggido

Yonsei University Health System Severance Hospital /ID# 271353, Seoul, Seoul Teugbyeolsi

SoonChunHyang University Seoul Hospital /ID# 264224, Seoul, Seoul Teugbyeolsi

Asan Medical Center /ID# 264228, Seoul, Seoul Teugbyeolsi

Hallym University Kangnam Sacred Heart Hospital /ID# 264226, Seoul, Seoul Teugbyeolsi

Eukarya PharmaSite /ID# 265307, Monterrey, Nuevo Leon

Sociedad de Metabolismo y Corazon S.C. /ID# 265915, Veracruz, Not set

Erasmus Medisch Centrum /ID# 263377, Rotterdam, Zuid-Holland

Clinical Trials New Zealand /ID# 265432, Hamilton, Waikato

Greenlane Clinical Centre /ID# 263191, Auckland, Not set

Stavanger Universitetssykehus /ID# 265997, Stavanger, Rogaland

Universitetssykehuset I Nord-Norge /ID# 265992, Tromsø, Troms

Oslo University Hospital - Rikshospitalet /ID# 265996, Oslo, Not set

Oftalmika sp. z o.o. /ID# 263087, Bydgoszcz, Kujawsko-pomorskie

DERMED Centrum Medyczne Sp. z o.o /ID# 263147, Lodz, Lodzkie

Santa Sp. z o..o. Santa Familia PTG Lodz /ID# 263181, Lodz, Lodzkie

Centrum Nowoczesnych Terapii 'Dobry Lekarz' sp.z.o.o. /ID# 263146, Krakow, Malopolskie

Klinika Ambroziak Dermatologia /ID# 263173, Warszawa, Mazowieckie

Unidade Local de Saude do Alto Ave, EPE /ID# 265158, Guimaraes, Braga

CUF Descobertas Hospital /ID# 263188, Lisbon, Lisboa

Unidade Local de Saude de Sao Jose, EPE /ID# 265155, Lisboa, Not set

Unidade Local de Saude de Santo Antonio, E.P.E. /ID# 265479, Porto, Not set

Private Practice - Dr. Alma Cruz /ID# 263204, Carolina, Not set

Clinical Research Puerto Rico /ID# 263450, San Juan, Not set

Spitalul Clinic Colentina /ID# 263303, Bucharest, Bucuresti

Private Practice - Dr. Orasan Remus /ID# 263305, Cluj Napoca, Cluj

Centrul Medical Euromed /ID# 263304, Bucharest, Not set

King Abdulaziz Medical City /ID# 266121, Jeddah, Makkah

King Saud University Med City /ID# 266120, Riyadh, Not set

Military Medical Academy /ID# 263257, Belgrade, Beograd

University Clinical Center Serbia /ID# 263256, Belgrade, Beograd

University Clinical Center Kragujevac /ID# 264211, Kragujevac, Sumadijski Okrug

University Clinical Center Vojvodina /ID# 263260, Novi Sad, Not set

National University Hospital /ID# 264673, Singapore, Not set

National Skin Centre /ID# 264680, Singapore, Not set

Univerzitna nemocnica L. Pasteura Kosice /ID# 263907, Košice, Kosicky Kraj

Fakultna nemocnica s poliklinikou Nove Zamky /ID# 265944, Nové Zámky, Nitriansky Kraj

Poliklinika Bezrucova (Cliniq s.r.o.) /ID# 263921, Bratislava, Not set

Fakultna nemocnica Trnava /ID# 263905, Trnava, Not set

University Medical Centre Ljubljana /ID# 265720, Ljubljana, Not set

University Medical Centre Maribor /ID# 265827, Maribor, Not set

Global Clinical Trials /ID# 262839, Pretoria, Gauteng

Life Chatsmed Garden Hospital /ID# 270237, Chatsworth, Kwazulu-Natal

Ahmed Al-Kadi Private Hospital /ID# 262837, Durban, Kwazulu-Natal

Dr Ahmed Ismail Manjra /ID# 262838, Westville, Kwazulu-Natal

Hospital Universitari Parc Tauli /ID# 262942, Sabadell, Barcelona

Hospital Universitario Marqués de Valdecilla /ID# 263039, Santander, Cantabria

Hospital Universitario Virgen de la Victoria /ID# 262941, Málaga, Malaga

Hospital de Manises /ID# 262938, Manises, Valencia

Hospital General Universitario Gregorio Marañón /ID# 262940, Madrid, Not set

Consorci Hospital General Universitario de Valencia /ID# 262944, Valencia, Not set

Karolinska University Hospital Solna /ID# 264530, Solna, Stockholms Lan

Universitetssjukhuset Örebro /ID# 265064, Örebro, Not set

Dermatology & Skin Care Clinic /ID# 264030, Buochs, Nidwalden

Kantonsspital St.Gallen /ID# 264238, St. Gallen, Sankt Gallen

University Hospital Zurich /ID# 266142, Zurich, Zuerich

Kaohsiung Chang Gung Memorial Hospital /ID# 264619, Kaohsiung City, Kaohsiung

National Taiwan University Hospital /ID# 264618, Taipei City, Taipei

Taichung Veterans General Hospital /ID# 270741, Taichung, Not set

Mackay Memorial Hospital /ID# 263661, Taipei City, Not set

Taipei Veterans General Hospital /ID# 265879, Taipei City, Not set

Linkou Chang Gung Memorial Hospital /ID# 264620, Taoyuan City, Not set

Queen Margaret Hospital /ID# 264198, Dunfermline, Fife

Gloucestershire Royal Hospital /ID# 265848, Gloucester, Gloucestershire

Disc_Barts Health NHS Trust - The Royal London Hospital /ID# 264121, London, Greater London

Harrogate District Hospital /ID# 265632, Harrogate, North Yorkshire

Bristol Royal Infirmary /ID# 263937, Bristol, Not set

Conditions: Hidradenitis Suppurativa

Learn More ›

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

NCT06661915

Recruiting

This phase II trial compares the effect of ASTX727 in combination with iadademstat to ASTX727 alone in treating patients with accelerated or blast phase Philadelphia chromosome negative myeloproliferative neoplasms (MPNs). ASTX727 is a combination of two drugs, cedazuridine and decitabine. Cedazuridine is in a class of medications called cytidine deaminase inhibitors. It prevents the breakdown of decitabine, making it more available in the body so that decitabine will have a greater effect. Deci... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: City of Hope Comprehensive Cancer Center LAO, Duarte, California +4 locations

Conditions: Accelerated Phase Myeloproliferative Neoplasm, Blast Phase Myeloproliferative Neoplasm, Essential Thrombocythemia, Myelodysplastic/Myeloproliferative Neoplasm, Myeloproliferative Neoplasm, Not Otherwise Specified, Polycythemia Vera, Primary Myelofibrosis, Secondary Myelofibrosis

Learn More ›

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

NCT06749457

Recruiting

The purpose of this study is to evaluate the safety and pharmacokinetics (PK) of AZD7760 when given as an intravenous infusion to healthy participants (Phase I) or participants with end-stage kidney disease receiving hemodialysis through a central venous catheter (Phase IIa).

Gender:

ALL

Ages:

Between 18 years and 55 years

Trial Updated:

06/17/2025

Locations: Research Site, Glendale, California +22 locations

Conditions: Staphylococcus Aureus

Learn More ›

Study of the Esophageal String Test (EST) for the Diagnosis of Helicobacter Pylori

NCT06871579

Recruiting

Background: Helicobacter pylori is a bacterium that infects the lining of the stomach and intestines. It can cause peptic ulcers, cancers, and infections. Current methods of diagnosing H. pylori infections have limitations. Researchers want to test a new method of testing for H. pylori. Objective: To compare the esophageal string test (EST) to standard tests for detecting H. pylori infection. Eligibility: People aged 18 years or older with persistent H. pylori infection. Design: Participa... Read More

Gender:

ALL

Ages:

Between 18 years and 99 years

Trial Updated:

06/17/2025

Locations: National Institutes of Health Clinical Center, Bethesda, Maryland

Conditions: Helicobacter Pylori

Learn More ›

A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis

NCT07003425

Recruiting

This is a multicenter, double-blind, Long-Term Extension (LTE) study to evaluate the long-term safety and efficacy of APG777 in patients with moderate-to-severe AD who have completed treatment in an APG777 Parent Study (NCT06395948). The LTE study will consist of 3 periods: 1) Screening Visit will coincide with the last visit of the Maintenance Period in the Parent Study 2) Extended Treatment Period 3) Post-treatment Follow-up Period. This study will be conducted in participants with atopic de... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: Investigational Site #25, Fountain Valley, California +31 locations

Investigational Site #25, Fountain Valley, California

Investigational Site #1, Coral Gables, Florida

Investigational Site #22, Margate, Florida

Investigational Site #28, Detroit, Michigan

Investigational Site #4, Troy, Michigan

Investigational Site #29, Wilmington, North Carolina

Investigational Site #32, Boardman, Ohio

Investigational Site #27, Mason, Ohio

Investigational Site #31, Portland, Oregon

Investigational Site #23, Nashville, Tennessee

Investigational Site #30, Frisco, Texas

Investigational Site #26, San Antonio, Texas

Investigational Site #6, Calgary, Alberta

Investigational Site #10, Edmonton, Alberta

Investigational Site #7, Fredericton, Brunswick

Investigational Site #3, Markham, Ontario

Investigational Site #5, Mississauga, Ontario

Investigational Site #24, Peterborough, Ontario

Investigational Site #11, Toronto, Ontario

Investigational Site #12, Toronto, Ontario

Investigational Site #9, Toronto, Ontario

Investigational Site #2, Montréal, Quebec

Investigational Site #8, Quebec City, Quebec

Investigational Site #14, Wrocław, Dolnoslaskie

Investigational Site #19, Wrocław, Dolnośląskie

Investigational Site #15, Lublin, Lubelskie

Investigational Site #18, Warszawa, Mazowieckie

Investigational Site #17, Gdańsk, Pomorskie

Investigational Site #13, Katowice, Silesia

Investigational Site #16, Sosnowiec, Silesia

Investigational Site #20, Kraków, Woj. Małopolskie

Investigational Site #21, Łódź, Not set

Conditions: Atopic Dermatitis

Learn More ›

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

NCT04079179

Recruiting

This is a research study of a drug called cobimetinib in children and adults diagnosed with Langerhans cell histiocytosis (LCH), and other histiocytic disorders that has returned or does not respond to treatment. Cobimetinib blocks activation of a protein called Mitogen-activated protein kinase (MEK) that is part of incorrect growth signals in histiocytosis cells. Four different groups of patients will be enrolled.

Gender:

ALL

Ages:

All

Trial Updated:

06/17/2025

Locations: Phoenix Children's Hospital, Phoenix, Arizona +11 locations

Conditions: Langerhan's Cell Histiocytosis, Juvenile Xanthogranuloma, Erdheim-Chester Disease, Rosai Dorfman Disease, Neuro-Degenerative Disease, Histiocytic Sarcoma, Histiocytic Disorders, Malignant

Learn More ›

A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine

NCT04965675

Recruiting

To find out if eptinezumab is better than placebo (normal saline solution) in lowering the number of days with migraine in young people ages 12 to 17 with chronic migraine.

Gender:

ALL

Ages:

Between 12 years and 17 years

Trial Updated:

06/17/2025

Locations: Yale-New Haven Children's Hospital, New Haven, Connecticut +74 locations

Yale-New Haven Children's Hospital, New Haven, Connecticut

Ki Health Partners LLC DBA New England Institute for Clinical Research, Stamford, Connecticut

Children's National Medical Center, Washington, District of Columbia

NW FL Clinical Research Group, LLC, Gulf Breeze, Florida

A G A Clinical Trials - HyperCore - PPDS, Hialeah, Florida

Axcess Medical Research, Loxahatchee Groves, Florida

University of South Florida, Tampa, Florida

University of Kentucky HealthCare (UKHC) Kentucky Clinic, Lexington, Kentucky

University of Maryland, Baltimore, Maryland

Michigan Head Pain and Neurological Institute, Ann Arbor, Michigan

Michigan State University - Department of Neurology, East Lansing, Michigan

Corewell Health Butterworth Hospital, Grand Rapids, Michigan

Dent Neurosciences Research Center Incorporated, Amherst, New York

North Suffolk Neurology-Commack, Commack, New York

OnSite Clinical Solutions, LLC - Randolph Rd - Charlotte - ClinEdge - PPDS, Charlotte, North Carolina

Cincinnati Children's Hospital Medical Center - PIN, Cincinnati, Ohio

The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Road Runner Research Ltd, San Antonio, Texas

Children's Specialty Group, Norfolk, Virginia

Mary Bridge Children's Hospital, Tacoma, Washington

Marshall University Medical Center, Huntington, West Virginia

Hospital Privado de La Comunidad, Mar Del Plata, Buenos Aires

Clínica Privada Independencia, Munro, Buenos Aires

Hospital Italiano de Buenos Aires, Ciudad Autónoma Buenos Aires, Ciudad Autónoma De BuenosAires

Expertia S.A- Mautalén Salud e Investigación, Ciudad Autónoma de Buenos Aires, Ciudad Autónoma De BuenosAires

Hospital Britanico de Buenos Aires, Ciudad Autónoma de Buenos Aires, Ciudad Autónoma De BuenosAires

Sanatorio Allende S.A, Ciudad De Cordoba, Córdoba

Hospital de Niños de La Santisima Trinidad, Córdoba-Barrio Crisol, Córdoba

Instituto Médico Río Cuarto, Río Cuarto, Córdoba

INECO Neurociencias Oroño, Rosario, Santa Fe

Centro de Investigaciones Médicas Tucumán - PPDS, San Miguel de Tucuman, Tucumán

University of Alberta, Edmonton, Alberta

Medical Arts Health Research Group - Penticton, Penticton, British Columbia

Vancouver Island Health Authority, Victoria, British Columbia

The Kids Clinic, Ajax, Ontario

London Health Sciences Centre -800 Commissioners Rd E, London, Ontario

Ospedale Pediatrico Bambino Gesù IRCCS, Roma, Lazio

IRCCS Istituto Giannina Gaslini, Genova, Liguria

Ospedale San Raffaele S.r.l. - INCIPIT - PIN, Milano, Lombardia

Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Lombardia

Fondazione Istituto Neurologico Nazionale Casimiro Mondino IRCCS, Pavia, Lombardia

Azienda Ospedaliero Universitaria Consorziale Policlinico, Bari, Puglia

AO Brotzu - Clinica di Neuropsichiatria dell'Infanzia e dell'Adolescenza - INCIPIT - PIN, Cagliari, Sardegna

Azienda Ospedaliero Universitaria A Meyer - INCIPIT - PIN, Firenze, Toscana

Centro de Investigacion Medico Biologica y de Terapia Avanzada S.C., Guadalajara, Jalisco

Unidad de Investigación en Salud de Chihuahua S.C., Zapopan, Jalisco

Centro de Investigacion Clinica Chapultepec S.A. de C.V. - Morelia, Morelia, Michoacán

ICARO Investigaciones en Medicina, S.A de C.V, Chihuahua, Not set

Neurociencias Estudios Clinicos S.C., Culiacán Sinaloa, Not set

Instituto de Investigationes Clinicas para la Salud A.C., Durango, Not set

Unidad de Investigación en Salud de Chihuahua S.C.-Mexico city, Mexico City, Not set

Clinical Research Institute SC-Mexico, Tepetlacalco, Not set

Centro de Estudios Clinicos Y Especialidades Medicas SC, Vista Hermosa, Not set

ULS de Almada-Seixal, EPE - Hospital Garcia de Orta, Almada, Setúbal

ULS de Coimbra, EPE - Hospital Pediátrico de Coimbra, Coimbra, Not set

ULS de São João, EPE - Hospital de São João, Porto, Not set

Childrens University Hospital, Belgrade, Not set

University Clinical Center Kragujevac, Kragujevac, Not set

Children and Youth Health Care Institute of Vojvodina, Novi Sad, Not set

Clinical Centre of Vojvodina, Novi Sad, Not set

CHUVI - H.U. Alvaro Cunqueiro, Vigo, Pontevedra

Hospital Universitario Vall d'Hebron - PPDS, Barcelona, Not set

Instituto del Sueño, Madrid, Not set

Hospital Clinico San Carlos, Madrid, Not set

Hospital Universitario Virgen del Rocio - PPDS, Sevilla, Not set

Hospital Universitari i Politecnic La Fe de Valencia, Valencia, Not set

Izmir City Hospital, Bayraklı, Izmir

Eskisehir Osmangazi Universitesi Tip Fakultesi Hastanesi, Eskisehir, Not set

Istanbul University Cerrahpasa Medical Faculty Hospital, Fatih/Istanbul, Not set

Mersin University Medical Faculty, Mersin, Not set

Royal Devon and Exeter Hospital NHS Trust, Exeter, Devon

Queen Elizabeth University Hospital - PPDS, Glasgow, Lanarkshire

Great Ormond Street Hospital, London, London, City Of

Royal Hospital for Children and Young People - PIN, Edinburgh, Midlothian

James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, Norfolk

Conditions: Chronic Migraine in Children

Learn More ›

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

NCT05554328

Recruiting

This phase II ComboMATCH treatment trial compares selumetinib plus olaparib to selumetinib alone in women with endometrial or ovarian (fallopian tube and primary peritoneal) cancer that has come back (recurrent) or that remains despite treatment (persistent) and harbors a mutation in the RAS pathway. Selumetinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Olaparib is an inhibitor of PARP, an enzyme that helps repair deoxyribonucleic acid (DNA) when... Read More

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama +269 locations

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama

University of South Alabama Mitchell Cancer Institute, Mobile, Alabama

Alaska Women's Cancer Care, Anchorage, Alaska

CTCA at Western Regional Medical Center, Goodyear, Arizona

Kingman Regional Medical Center, Kingman, Arizona

PCR Oncology, Arroyo Grande, California

Cedars Sinai Medical Center, Los Angeles, California

Saint Joseph Hospital - Orange, Orange, California

Stanford Cancer Institute Palo Alto, Palo Alto, California

Presbyterian Intercommunity Hospital, Whittier, California

UM Sylvester Comprehensive Cancer Center at Aventura, Aventura, Florida

UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables, Florida

UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida

Mayo Clinic in Florida, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

UM Sylvester Comprehensive Cancer Center at Kendall, Miami, Florida

UM Sylvester Comprehensive Cancer Center at Plantation, Plantation, Florida

The Queen's Medical Center - West Oahu, 'Ewa Beach, Hawaii

Queen's Cancer Cenrer - POB I, Honolulu, Hawaii

Queen's Medical Center, Honolulu, Hawaii

University of Hawaii Cancer Center, Honolulu, Hawaii

Queen's Cancer Center - Kuakini, Honolulu, Hawaii

Kapiolani Medical Center for Women and Children, Honolulu, Hawaii

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho

Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho

Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho

Saint Luke's Cancer Institute - Meridian, Meridian, Idaho

Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho

Saint Luke's Cancer Institute - Nampa, Nampa, Idaho

Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho

Kootenai Clinic Cancer Services - Sandpoint, Sandpoint, Idaho

Saint Luke's Cancer Institute - Twin Falls, Twin Falls, Idaho

Advocate Good Shepherd Hospital, Barrington, Illinois

Illinois CancerCare-Bloomington, Bloomington, Illinois

Illinois CancerCare-Canton, Canton, Illinois

Illinois CancerCare-Carthage, Carthage, Illinois

Centralia Oncology Clinic, Centralia, Illinois

John H Stroger Jr Hospital of Cook County, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Advocate Illinois Masonic Medical Center, Chicago, Illinois

AMG Crystal Lake - Oncology, Crystal Lake, Illinois

Carle at The Riverfront, Danville, Illinois

Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois

Decatur Memorial Hospital, Decatur, Illinois

Illinois CancerCare-Dixon, Dixon, Illinois

Advocate Good Samaritan Hospital, Downers Grove, Illinois

Carle Physician Group-Effingham, Effingham, Illinois

Crossroads Cancer Center, Effingham, Illinois

Advocate Sherman Hospital, Elgin, Illinois

Illinois CancerCare-Eureka, Eureka, Illinois

NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois

Illinois CancerCare-Galesburg, Galesburg, Illinois

NorthShore University HealthSystem-Glenbrook Hospital, Glenview, Illinois

Advocate South Suburban Hospital, Hazel Crest, Illinois

NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois

Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois

AMG Libertyville - Oncology, Libertyville, Illinois

Condell Memorial Hospital, Libertyville, Illinois

Illinois CancerCare-Macomb, Macomb, Illinois

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois

UC Comprehensive Cancer Center at Silver Cross, New Lenox, Illinois

Cancer Care Center of O'Fallon, O'Fallon, Illinois

Advocate Christ Medical Center, Oak Lawn, Illinois

University of Chicago Medicine-Orland Park, Orland Park, Illinois

Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois

Advocate Lutheran General Hospital, Park Ridge, Illinois

Illinois CancerCare-Pekin, Pekin, Illinois

Illinois CancerCare-Peoria, Peoria, Illinois

Illinois CancerCare-Peru, Peru, Illinois

Illinois CancerCare-Princeton, Princeton, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Springfield Clinic, Springfield, Illinois

Springfield Memorial Hospital, Springfield, Illinois

Carle Cancer Center, Urbana, Illinois

Illinois CancerCare - Washington, Washington, Illinois

UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny, Iowa

UI Health Care Mission Cancer and Blood - Des Moines Clinic, Des Moines, Iowa

Mercy Medical Center - Des Moines, Des Moines, Iowa

UI Health Care Mission Cancer and Blood - Waukee Clinic, Waukee, Iowa

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Ochsner Baptist Medical Center, New Orleans, Louisiana

Ochsner Medical Center Jefferson, New Orleans, Louisiana

Harold Alfond Center for Cancer Care, Augusta, Maine

Lafayette Family Cancer Center-EMMC, Brewer, Maine

MaineHealth Maine Medical Center- Scarborough, Scarborough, Maine

University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

National Institutes of Health Clinical Center, Bethesda, Maryland

UPMC Western Maryland, Cumberland, Maryland

Tufts Medical Center, Boston, Massachusetts

Baystate Medical Center, Springfield, Massachusetts

Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan

Trinity Health Medical Center - Brighton, Brighton, Michigan

University of Michigan - Brighton Center for Specialty Care, Brighton, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan

Trinity Health Medical Center - Canton, Canton, Michigan

Chelsea Hospital, Chelsea, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan

Corewell Health Dearborn Hospital, Dearborn, Michigan

Corewell Health Farmington Hills Hospital, Farmington Hills, Michigan

Cancer Hematology Centers - Flint, Flint, Michigan

Genesee Hematology Oncology PC, Flint, Michigan

Genesys Hurley Cancer Institute, Flint, Michigan

Hurley Medical Center, Flint, Michigan

University of Michigan Health - Sparrow Lansing, Lansing, Michigan

Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan

Henry Ford Saint John Hospital - Macomb Medical, Macomb, Michigan

Corewell Health William Beaumont University Hospital, Royal Oak, Michigan

Corewell Health Beaumont Troy Hospital, Troy, Michigan

Huron Gastroenterology PC, Ypsilanti, Michigan

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan

Mercy Hospital, Coon Rapids, Minnesota

Essentia Health - Deer River Clinic, Deer River, Minnesota

Essentia Health Cancer Center, Duluth, Minnesota

Fairview Southdale Hospital, Edina, Minnesota

Essentia Health Hibbing Clinic, Hibbing, Minnesota

Fairview Clinics and Surgery Center Maple Grove, Maple Grove, Minnesota

Abbott-Northwestern Hospital, Minneapolis, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota

Regions Hospital, Saint Paul, Minnesota

United Hospital, Saint Paul, Minnesota

Essentia Health Sandstone, Sandstone, Minnesota

Essentia Health Virginia Clinic, Virginia, Minnesota

Saint Francis Medical Center, Cape Girardeau, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Community Hospital of Anaconda, Anaconda, Montana

Billings Clinic Cancer Center, Billings, Montana

Bozeman Health Deaconess Hospital, Bozeman, Montana

Benefis Sletten Cancer Institute, Great Falls, Montana

Logan Health Medical Center, Kalispell, Montana

Community Medical Center, Missoula, Montana

OptumCare Cancer Care at Seven Hills, Henderson, Nevada

OptumCare Cancer Care at Charleston, Las Vegas, Nevada

OptumCare Cancer Care at Fort Apache, Las Vegas, Nevada

Jersey City Medical Center, Jersey City, New Jersey

Monmouth Medical Center Southern Campus, Lakewood, New Jersey

Monmouth Medical Center, Long Branch, New Jersey

Memorial Sloan Kettering Monmouth, Middletown, New Jersey

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

Sidney Kimmel Cancer Center Washington Township, Sewell, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Roswell Park Cancer Institute, Buffalo, New York

Memorial Sloan Kettering Commack, Commack, New York

Memorial Sloan Kettering Westchester, Harrison, New York

Memorial Sloan Kettering Cancer Center, New York, New York

State University of New York Upstate Medical University, Syracuse, New York

Duke University Medical Center, Durham, North Carolina

Duke Women's Cancer Care Raleigh, Raleigh, North Carolina

Sanford Broadway Medical Center, Fargo, North Dakota

Sanford Roger Maris Cancer Center, Fargo, North Dakota

UH Seidman Cancer Center at UH Avon Health Center, Avon, Ohio

UHHS-Chagrin Highlands Medical Center, Beachwood, Ohio

Strecker Cancer Center-Belpre, Belpre, Ohio

Aultman Health Foundation, Canton, Ohio

Miami Valley Hospital South, Centerville, Ohio

Adena Regional Medical Center, Chillicothe, Ohio

Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio

Case Western Reserve University, Cleveland, Ohio

Ohio State University Comprehensive Cancer Center, Columbus, Ohio

Mount Carmel East Hospital, Columbus, Ohio

Riverside Methodist Hospital, Columbus, Ohio

The Mark H Zangmeister Center, Columbus, Ohio

Miami Valley Hospital, Dayton, Ohio

Dayton Physician LLC - Englewood, Dayton, Ohio

Miami Valley Hospital North, Dayton, Ohio

Dublin Methodist Hospital, Dublin, Ohio

Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio

Miami Valley Cancer Care and Infusion, Greenville, Ohio

Kettering Medical Center, Kettering, Ohio

Fairfield Medical Center, Lancaster, Ohio

OhioHealth Mansfield Hospital, Mansfield, Ohio

Marietta Memorial Hospital, Marietta, Ohio

Memorial Hospital, Marysville, Ohio

UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor, Ohio

Knox Community Hospital, Mount Vernon, Ohio

Licking Memorial Hospital, Newark, Ohio

Mercy Health - Perrysburg Hospital, Perrysburg, Ohio

OhioHealth Pickerington Methodist Hospital, Pickerington, Ohio

Southern Ohio Medical Center, Portsmouth, Ohio

Springfield Regional Cancer Center, Springfield, Ohio

Springfield Regional Medical Center, Springfield, Ohio

Mercy Health - Saint Anne Hospital, Toledo, Ohio

Upper Valley Medical Center, Troy, Ohio

Saint Ann's Hospital, Westerville, Ohio

OhioHealth Westerville Medical Campus/Westerville Cancer Center, Westerville, Ohio

UH Seidman Cancer Center at Saint John Medical Center, Westlake, Ohio

Genesis Healthcare System Cancer Care Center, Zanesville, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Providence Newberg Medical Center, Newberg, Oregon

Saint Alphonsus Cancer Care Center-Ontario, Ontario, Oregon

Providence Willamette Falls Medical Center, Oregon City, Oregon

Providence Portland Medical Center, Portland, Oregon

Providence Saint Vincent Medical Center, Portland, Oregon

Oregon Health and Science University, Portland, Oregon

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania

UPMC Altoona, Altoona, Pennsylvania

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania

Bryn Mawr Hospital, Bryn Mawr, Pennsylvania

Pocono Medical Center, East Stroudsburg, Pennsylvania

UPMC Hillman Cancer Center Erie, Erie, Pennsylvania

UPMC Cancer Centers - Arnold Palmer Pavilion, Greensburg, Pennsylvania

UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion, Mechanicsburg, Pennsylvania

Riddle Memorial Hospital, Media, Pennsylvania

UPMC Hillman Cancer Center - Monroeville, Monroeville, Pennsylvania

Paoli Memorial Hospital, Paoli, Pennsylvania

Pennsylvania Hospital, Philadelphia, Pennsylvania

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania

Fox Chase Cancer Center, Philadelphia, Pennsylvania

UPMC-Magee Womens Hospital, Pittsburgh, Pennsylvania

University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania

UPMC-Passavant Hospital, Pittsburgh, Pennsylvania

Asplundh Cancer Pavilion, Willow Grove, Pennsylvania

Lankenau Medical Center, Wynnewood, Pennsylvania

Women and Infants Hospital, Providence, Rhode Island

Rapid City Regional Hospital, Rapid City, South Dakota

Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

MD Anderson in The Woodlands, Conroe, Texas

Lyndon Baines Johnson General Hospital, Houston, Texas

M D Anderson Cancer Center, Houston, Texas

MD Anderson West Houston, Houston, Texas

MD Anderson League City, League City, Texas

MD Anderson in Sugar Land, Sugar Land, Texas

Virginia Cancer Institute, Richmond, Virginia

VCU Massey Cancer Center at Stony Point, Richmond, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Carilion Roanoke Memorial Hospital, Roanoke, Virginia

VCU Community Memorial Health Center, South Hill, Virginia

Swedish Cancer Institute-Edmonds, Edmonds, Washington

Swedish Cancer Institute-Issaquah, Issaquah, Washington

Providence Regional Cancer System-Lacey, Lacey, Washington

Valley Medical Center, Renton, Washington

Swedish Medical Center-First Hill, Seattle, Washington

Providence Saint Mary Regional Cancer Center, Walla Walla, Washington

North Star Lodge Cancer Center at Yakima Valley Memorial Hospital, Yakima, Washington

Edwards Comprehensive Cancer Center, Huntington, West Virginia

West Virginia University Healthcare, Morgantown, West Virginia

Duluth Clinic Ashland, Ashland, Wisconsin

Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin

Aurora Saint Luke's South Shore, Cudahy, Wisconsin

Aurora Health Care Germantown Health Center, Germantown, Wisconsin

Aurora Cancer Care-Grafton, Grafton, Wisconsin

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin

Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin

Aurora BayCare Medical Center, Green Bay, Wisconsin

Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin

Gundersen Lutheran Medical Center, La Crosse, Wisconsin

University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison, Wisconsin

University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin

Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin

Aurora Cancer Care-Milwaukee, Milwaukee, Wisconsin

Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin

Aurora Sinai Medical Center, Milwaukee, Wisconsin

Saint Vincent Hospital Cancer Center at Oconto Falls, Oconto Falls, Wisconsin

Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin

Aurora Cancer Care-Racine, Racine, Wisconsin

Saint Vincent Hospital Cancer Center at Sheboygan, Sheboygan, Wisconsin

Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin

Saint Vincent Hospital Cancer Center at Sturgeon Bay, Sturgeon Bay, Wisconsin

Aurora Medical Center in Summit, Summit, Wisconsin

Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin

Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin

Aurora West Allis Medical Center, West Allis, Wisconsin

Puerto Rico Hematology Oncology Group, Bayamon, Not set

Centro Comprensivo de Cancer de UPR, San Juan, Not set

Conditions: Recurrent Endometrial Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Fallopian Tube Carcinoma, Recurrent Primary Peritoneal Carcinoma

Learn More ›

Evaluating Treatments for Suicidal Veterans With PTSD

NCT05974631

Recruiting

Posttraumatic Stress Disorder (PTSD) is a significant driver of suicide risk among Veterans, but there is a critical knowledge gap about how to treat PTSD among people at elevated risk for suicide. Although evidence-based treatments for PTSD reduce suicide risk, Veterans at high risk for suicidal behavior rarely receive these potentially life-saving treatments. Prior research suggests that a treatment that combines Dialectical Behavior Therapy (DBT) with the DBT Prolonged Exposure protocol (DBT... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis, Minnesota +2 locations

Conditions: Self-directed Violence, Post-traumatic Stress Disorder (PTSD)

Learn More ›

A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation

NCT06200207

Recruiting

The study is being done to see if ziltivekimab can be used to treat participants living with heart failure and inflammation. Participants will either get ziltivekimab (active medicine) or placebo (inactive substance that looks like the study medicine but does not contain any medicine). The treatment participants get is decided by chance. Participant's chance of getting ziltivekimab or placebo is the same. Ziltivekimab is not yet approved in any country or region in the world. It is a new medicin... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: Advanced Cardiovascular, LLC, Alexander City, Alabama +222 locations

Advanced Cardiovascular, LLC, Alexander City, Alabama

Eastern Shore Rsrch Inst, LLC, Fairhope, Alabama

Cardiology & Medicine Clinic, Little Rock, Arkansas

Valley Clinical Trials, Inc., Northridge, California

UCI Health, Orange, California

South California Heart Spc, Pasadena, California

Clearwater Cardiovascular Consultants, Largo, Florida

Ocala Cardiovascular Research, Ocala, Florida

Ormond Beach Clinical Research, Ormond Beach, Florida

St Johns Ctr Clin Rsch-St. Aug, Saint Augustine, Florida

GA Arrhythmia Cons & Rsch Inst, Macon, Georgia

Velocity Clin Rsrch - Savannah, Savannah, Georgia

Chicago Medical Research LLC, Hazel Crest, Illinois

UofL Health Care Outpatient, Louisville, Kentucky

Maryland Cardiovascular Specialists - Baltimore, Baltimore, Maryland

MD Medical Research, Oxon Hill, Maryland

Cardio and Vascular Assoc-CAVA, Bloomfield Hills, Michigan

Millennium Cardiology, Farmington Hills, Michigan

Kansas City VA Medical Center, Kansas City, Missouri

Washington University, Saint Louis, Missouri

Renown Regional Medical Center, Reno, Nevada

Long Island Cardiovascular Consultants PC, Lake Success, New York

Mount Sinai Hosp at NYC, New York, New York

Northwell Health Phys Cardio, Riverhead, New York

University Of North Carolina At Chapel Hill, Chapel Hill, North Carolina

AMS Cardiology, Horsham, Pennsylvania

University of Pennsylvania Hospital, Philadelphia, Pennsylvania

PharmaTex Research, Amarillo, Texas

University of Texas Southwestern Medical Center, Dallas, Texas

David Turbay, MD, PLLC, El Paso, Texas

Private Practice Leadership LLC., Katy, Texas

Clinical Advancement Ctr, PLLC, San Antonio, Texas

Sherman Clinical Research, Sherman, Texas

Northwest Heart Center, Tomball, Texas

Sentara Clinical Research, Norfolk, Virginia

Virginia Commonwealth University, Richmond, Virginia

Centro Médico CIMEL, Lanus Este, Buenos Aires

Instituto de Investigaciones Clinicas Quilmes SRL, Buenos Aires, Not set

CIPREC Pueyrredon, Buenos Aires, Not set

Centro Medico Dra. Laura Maffei e Investigacion Clínica Apli, Buenos Aires, Not set

Centro de Investigación y Prevención Cardiovascular, Caba, Not set

Cardiologia Palermo_LOC#1, City of Buenos Aires, Not set

Sanatorio Esperanza, Esperanza, Santa Fe, Not set

Consultorio Integral de Atención al Diabético, Morón, Not set

Centro Cardiovascular Salta, Salta, Not set

Investigaciones Clinicas Tucuman, San Miguel De Tucumán, Tucumán., Not set

The Canberra Hospital_Garran, Garran, Australian Capital Territory

John Hunter Hospital, New Lambton Heights, New South Wales

Illawarra Heart Health Centre, Wollongong, New South Wales

The Prince Charles Hospital, Brisbane, Queensland

Ballarat Base Hospital, Ballarat, Victoria

The Cardiologists Pty Ltd, Epping, Victoria

Advara HeartCare, Mulgrave, Victoria

Fiona Stanley Hospital Cardiology, Murdoch, Western Australia

MHAT "Puls" AD Cardiology Department, Blagoevgrad, Not set

MHAT Haskovo AD, Haskovo, Not set

MHAT Heart and Brain, Pleven, Not set

"UMHAT "Sveti Georgi" EAD, Plovdiv, Not set

"Medical Center Hera" EOOD - Sofia, Sofia, Not set

Medical center ISUL - Tsaritsa Yoanna EOOD, Sofia, Not set

"UMHATEM N.I. Pirogov" EAD, Sofia, Not set

"UMHAT "Sveta Anna" Sofia" AD, Clinic of Cardiology, Sofia, Not set

Medical Center Synexus Sofia, Sofia, Not set

University of Calgary_Calgary, Calgary, Alberta

Cambridge Cardiac Care Centre, Cambridge, Ontario

Saul Vizel Pro. Med. Corp, Cambridge, Ontario

Corcare Cardiovascular Research, Scarborough, Ontario

Diabetes Heart Research Centre, Toronto, Ontario

CPS Research, Waterloo, Ontario

Clinical Research Solutions Inc., Waterloo, Ontario

Institut de Cardiologie de Montreal, Montreal, Quebec

Montreal General Hospital, Montreal, Quebec

CHU de Quebec-Uni Laval-Hotel, Quebec, Not set

Innera s.r.o., Benešov, Not set

Kardiologicka ambulance Brno s.r.o., Brno, Not set

Vojenská nemocnice Brno p.o., Brno, Not set

Ordinace pro choroby srdce, Chomutov, Not set

MEDICON a.s., Praha 7, Not set

Svitavska nemocnice Kardiologie, Svitavy, Not set

Kardiologie Trutnov Ferkl, Trutnov, Not set

Nemocnice AGEL Třinec-Podlesí a.s., Třinec, Not set

Centre Hospitalier Regional Universitaire de Tours-Hopital Trousseau, Chambray Les Tours, Not set

Centre Hospitalier Universitaire de Poitiers, Poitiers, Not set

Centre Hospitalier Universitaire de Rennes - Hopital Pontchaillou, Rennes, Not set

Centre Hospitalier Universitaire de Rouen-Hopital Charles Nicolle, Rouen cedex, Not set

Centre Hospitalier Intercommunal Toulon La Seine-Sur-Mer - Hopital Sainte Musse, Toulon, Not set

Polyclinique Vauban, Valenciennes, Not set

Chru de Nancy - Hopital Brabois, Vandoeuvre Les Nancy, Not set

Kardiologisch-Angiologische Praxis Herzzentrum Bremen, Bremen, Not set

Herzzentrum Dresden GmbH Universitätsklinik, Dresden, Not set

Zentrum fuer klinische Studien Suedbrandenburg GmbH, Elsterwerda, Not set

Hospitalvereinigung TH-Kath. KH St. Johann Nepomuk-Innere Med. II, Erfurt, Not set

MVZ CCB Frankfurt Und Main-Taunus GbR, Frankfurt, Not set

Medical Center - University Of Freiburg, Freiburg, Not set

MVZ im Altstadt-Carree Fulda GmbH - Zentrum für klinische Studien, Fulda, Not set

UKS - Innere Medizin III, Homburg, Not set

Kardiopraxis Schirmer, Kaiserslautern, Not set

Gesundheitscentrum Mainz (Regner / Schmitt), Mainz, Not set

Alexandra General Hospital, Therapeutic Clinic, Athens, Attiki

Evangelismos Hospital, Athens, Not set

Naval Hospital of Athens, Athens, Not set

"Laiko" General Hospital of Athens, Athens, Not set

'G. Gennimatas' General Hospital of Athens, Athens, Not set

Konstantopouleio G.H. of Athens, "Agia Olga", Athens, Not set

"Hygeia" General Hospital of Athens, Athens, Not set

Metropolitan General Hospital Healthcare Facilities Operation And Management Single Member S.A., Athens, Not set

Naval Hospital of Athens, Athens, Not set

U.G.H of Athens "Attikon", Chaidari, Athens, Not set

General Hospital of Chalkida, Chalkida, Not set

General Hospital of Chios "Skilitsio", Chios, Not set

Univ Gen Hospital Larisa, Cardiology Medicine Clinic, Larissa, Not set

Sismanogleio General Hospital, Marousi, Not set

"AHEPA" University General Hospital of Thessaloniki, Thessaloniki, Not set

'Ippokrateio' General Hospital of Thessaloniki, Thessaloniki, Not set

Gen Hospital of Thessaloniki G.Papanikolaou,Cardiology Dpt, Thessaloniki, Not set

Siddhartha Medical College & Government General Hospital, Vijaywada, Andhra Pradesh

King George Hospital, Visakhapatnam, Andra Pradesh

G B Pant Institute of Postgraduate Medical Education and Research, New Delhi, Delhi

All India Institute of Medical Sciences (AIIMS), New Delhi, Delhi

Vardhaman Mahavir Medical College & Safdarjung Hospital, New Delhi, Delhi

Sir Ganga Ram Hospital, New Delhi, Delhi

Rajiv Gandhi Super Speciality Hospital, New Delhi, Delhi

Rhythm Heart Institute, Vadodara, Gujarat

KLE's Dr. Prabhakar Kore Hospital & Medical Research Centre, Belagavi, Karnataka

St John's Medical College Hospital, Bengaluru, Karnataka

Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bengaluru, Karnataka

Manipal Hospital, Mysuru, Mysuru, Karnataka

Kasturba Medical College and Hospital, Manipal, Udupi, Karnataka

Sengupta Hospital and Research Institute, Nagpur, Maharashtra

All India Institute of Medical Sciences (AIIMS), Nagpur, Nagpur, Maharashtra

Chopda Medicare and Research Centre Pvt. Ltd., Nashik, Maharashtra

Vijan Hospital & Research Centre, Nashik, Maharashtra

Villoo Poonawalla Memorial Hospital, Pune, Maharashtra

All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Bhubaneswar, Odisha

S.P. Medical College & Associated Group of Hospitals, Bikaner, Rajasthan

Guru Nanak CARE Hospitals, Hyderabad, Telangana

Malla Reddy Narayana Multispeciality Hospital, Hyderabad, Telangana

Ganesh Shankar Vidyarthe Memorial (GSVM) Medical College, Kanpur, Uttar Pradesh

Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh

Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh

Jawaharlal Nehru Medical College and Hospital, Aligarh, Utter Pradesh

B M Birla Heart Research Centre, Kolkata, West Bengal

Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, Not set

Hospital Sultanah Aminah, Johor Bahru, Johor

Hospital Sultanah Bahiyah, Alor Setar, Kedah

Hospital Tengku Ampuan Afzan, Kuantan, Pahang

Hospital Raja Permaisuri Bainun Ipoh, Ipoh, Perak

Hospital Serdang, Kajang, Selangor

University Malaya Medical Centre, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur

Hospital Raja Perempuan Zainab II, Kota Bharu, Kelantan, Not set

Pratia S.A., Jelenia Góra, Dolnoslaskie

4 Wojskowy Szpital Kliniczny Z Poliklinika Samodzielny Publiczny Zaklad Opieki Zdrowotnej We Wroclawiu, Wroclaw, Dolnoslaskie

Centrum Medyczne Intercor Sp. z o.o., Bydgoszcz, Kujawsko-Pomorskie

Kardio Life, Włocławek, Kujawsko-pomorskie

Uniwersytecki Szpital Kliniczny nr 2 Uniwersytetu Medycznego w Łodzi, Lodz, Lodzkie

Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika, Lodz, Lodzkie

Samodzielny Publiczny Zaklad Opieki Zdrowotnej W Pulawach, Pulawy, Lubelskie

Cardiomedicum Sp. z o.o., Kraków, Malopolskie

Formed 2 Sp. z o.o., Oswiecim, Malopolskie

Prywatna Praktyka Lekarska Anna Chudoba, Żyrardów, Masovian

Linden sp. z o.o. sp. k., Kraków, Małopolskie

Uniwersytecki Szpital Kliniczny w Bialymstoku, Białystok, Podlaskie

Ind. Prak. Lek. w dziedz. Kardiologii lek. med. K. Cymerman, Gdynia, Pomorskie

Szpitale Pomorskie Sp. z o.o., Gdynia, Pomorskie

American Heart of Poland S.A., Bielsko-Biała, Not set

10 Wojskowy Szpital Kliniczny z Polikliniką - Samodzielny Publiczny Zakład Opieki Zdrowotnej w Bydgoszczy, Bydgoszcz, Not set

Szpitale Pomorskie Sp. z o.o., Gdynia, Not set

Zanamed Medical Clinic Sp. z o.o., Lublin, Not set

Trialmed Sp. z o. o., Piotrków Trybunalski, Not set

Uniwersytecki Szpital Kliniczny W Poznaniu, Poznan, Not set

American Heart of Poland S.A., Tychy, Not set

Panstwowy Instytut Medyczny Ministerstwa Spraw Wewnetrznych I Administracji, Warszawa, Not set

CHTâmega e Sousa - Hospital Padre Américo, Guilhufe - Penafiel, Not set

Hospital da Luz, Lisboa, Not set

Centro Hospitalar Lisboa Norte, Lisboa, Not set

CHLO, EPE - Hospital São Francisco Xavier, Lisbon, Not set

Centro Hospitalar de Setubal, Setubal, Not set

Hospital Vithas Sevilla, Castilleja De La Cuesta. Sevilla, Andalucia

Hospital Universitario de Salamanca, Salamanca, Castilla Y León

Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Madrid

Hospital Gregorio Marañón, Madrid, Not set

Hospital Ramón y Cajal, Madrid, Not set

Hospital Virgen del Camino - Sanlúcar de Barrameda, Sanlúcar de Barrameda, Not set

Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Not set

Clínica Nuevas Tecnologías en Diabetes y Endocrinología, Sevilla, Not set

Fundación para la Investigación del Hospital Clínico de Valencia (INCLIVA), Valencia, Not set

Eskisehir Osmangazi University Sağlık Uygulama ve Arastirma, Eskisehir, Odunpazari

T.C. Saglık Bakanlıgı Adana Sehir Egitim ve Arastirma Hastan, Adana, Not set

Afyonkarahisar Health Sciences University, Afyon, Not set

Ankara Sehir Hastanesi Cardiology, Ankara, Not set

Bursa Sehir Hastanesi Cardiology, Bursa, Not set

Trakya University, Edirne, Not set

Basaksehir Cam ve Sakura Sehir Hastanesi, Istanbul, Not set

Erciyes University Cardiology, Kayseri, Not set

Kocaeli Universitesi Tip Fakultesi Hastanesi, Kocaeli, Not set

Raigmore Hospital, Inverness, Highland

St. Richards Hospital, Chichester, West Sussex

FutureMeds, Birmingham, Not set

Ninewells Hospital, Dundee, Not set

Peterborough City Hospital, Peterborough, Not set

Conditions: Heart Failure, Systemic Inflammation

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Modeling Host-Pathogen Interaction Using Lymphoid Organoids

NCT06479837

Recruiting

Background: Staphylococcus aureus (S. aureus) are bacteria that can make people sick. Sometimes, an S. aureus infection can develop inside the spine; these infections can lead to paralysis and death. Researchers do not know how S. aureus interacts with a person s cells to cause infections in the spine. Objective: To learn how S. aureus interacts with cells in the body using tissues from tonsils discarded after standard surgery to remove them. Eligibility: People aged 2 years and older who a... Read More

Gender:

ALL

Ages:

Between 2 years and 120 years

Trial Updated:

06/17/2025

Locations: National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, Maryland +1 locations

Conditions: Staphylococcal Infections

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